Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. How...Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. However, standalone PVRs are limited by their individual storage capacities, restricting the number of programs they can store. While online catch-up TV services such as Hulu and Netflix mitigate this limitation by offering on-demand access to broadcast programs shortly after their initial broadcast, they require substantial storage and network resources, leading to significant infrastructural costs for service providers. To address these challenges, we propose a collaborative TV content recording system that leverages distributed PVRs, combining their storage into a virtual shared pool without additional costs. Our system aims to support all concurrent playback requests without service interruption while ensuring program availability comparable to that of local devices. The main contributions of our proposed system are fourfold. First, by sharing storage and upload bandwidth among PVRs, our system significantly expands the overall recording capacity and enables simultaneous recording of multiple programs without the physical constraints of standalone devices. Second, by utilizing erasure coding efficiently, our system reduces the storage space required for each program, allowing more programs to be recorded compared to traditional replication. Third, we propose an adaptive redundancy scheme to control the degree of redundancy of each program based on its evolving playback demand, ensuring high-quality playback by providing sufficient bandwidth for popular programs. Finally, we introduce a contribution-based incentive policy that encourages PVRs to actively participate by contributing resources, while discouraging excessive consumption of the combined storage pool. Through extensive experiments, we demonstrate the effectiveness of our proposed collaborative TV program recording system in terms of storage efficiency and performance.展开更多
This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(...This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(SAR ADC) is shared among all 20 channels. A charge-sharing multiplexer(MUX) is proposed to transmit the output signals from the respective channels to the ADC. By separately pre sampling the output of each channel, the sampling time of each channel is greatly extended and additional active buffers are avoided. The AFE is fabricated in a 65-nm CMOS process, and the whole system consumes 28.2 μW under 1 V supply. Each analog acquisition channel consumes 1.25 μW and occupies a chip area of 0.14 mm2. Measurement results show that the AFE achieves an input referred noise of 1.8 μV·rms in a 350 Hz bandwidth and a noise efficiency factor(NEF) of 4.1. The 12-bit SAR ADC achieves an ENOB of 9.8 bit operating at 25 k S/s. The AFE is experimented on real-world applications by measuring human ECG and a clear ECG waveform is captured.展开更多
The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “o...The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “onozuka” R\|10, 0\^01% pectolyase Y\|23,0\^15% macerozyme R\|10 and 0\^1% hemicellulase at 25℃. Outward and inward single channels in plasma membrane were observed using cell\|attached recording of patch\|clamp technique. In this study, single channel records showed that more than one species of channel were obtained. These attempts in protoplast isolation and ion channel recording offers the opportunity to characterize cellular mechanisms of salt tolerance in tree species.展开更多
A microelectrode array(MEA) is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair ...A microelectrode array(MEA) is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair consists of one stimulating electrode and one recording electrode. Supported by the peripheral circuits, four electrode states to study the bioelectrical signal of biological tissue or slice cultured in-vitro on the surface of the electrodes can be realized through each pair of electrodes. The four electrode states are stimulation, recording, stimulation and recording simultaneously, and isolation. The state of each pair of working electrodes can be arbitrarily controlled according to actual needs. The MEAs are fabricated in printed circuit board (PCB) technology. The total area of the PCB-based MEA is 49 mm × 49 mm. The impedance measurement of MEA is carried out in 0.9% sodium chloride solution at room temperature by means of 2-point measurements with an Agilent LCR meter, and the test signal for the impedance measurement is sinusoidal (AC voltage 50 mV, sweeping frequency 20 Hz to 10 kHz). The electrode impedance is between 200 and 3 kΩ while the frequency is between 500 and 1 000 Hz. The electrode impedance magnitude is inversely proportional to the frequency. Experiments of toad sciatic nerve in-vitro stimulation and recording and signal regeneration between isolated toad sciatic nerves are carried out on the PCB-based MEA. The results show that the MEA can be used for bioelectrical signal stimulation, recording, stimulation and recording simultaneously, and isolation of biological tissues or slices in-vitro.展开更多
In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location ...In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location method for extra high voltage and long distance transmission lines.展开更多
Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a (hASIC1a) current in HEK293 cells with a modified perfusion methods...Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a (hASIC1a) current in HEK293 cells with a modified perfusion methods. Methods With cell floating method, which is separating the cultured cell from coverslip and putting the cell in front of perfusion tubing, whole cell patch clamp technique was used to record hASICla currents evoked by low pH external solution. Results Using cell floating method, the amplitude of hASICla currents activated by pH 5.0 in HEK293 cells is twice as large as that by the conventional method where the cells remain attached to coverslip. The time to reach peak at two different recording conditions is (21±5) ms and (270±25) ms, respectively. Inactivation time constants are (496±23) ms and (2284±120) ms, respectively. The cell floating method significantly increases the amiloride potency of block on hASIC 1 a [IC50 is (3.4± 1.1 ) μmol/L and (2.4± 0.9) μmol/L, respectively]. Both recording methods have similar pH activation ECs0 (6.6±0.6, 6.6±0.7, respectively). Conclusion ASICs channel activation requires fast exchange of extracellular solution with the different pH values. With cell floating method, the presence of hASIC la current was re-confirmed and the biophysical and pharmacological properties of hASIC la channel in HEK293 cells was precisely characterized. This method could be used to study all ASICs and other ligand-gated channels that require fast extracellular solution exchange.展开更多
Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission ...Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission are associated with pathophysiological and neurodegenerative disorders,whereas glucagon-like peptide-1 has demonstrated neuroprotective effects.However,it is not yet clear whether diabetes causes alterations in inhibitory input to retinal ganglion cells and whether and how glucagon-like peptide-1 protects against neurodegeneration in the diabetic retina through regulating inhibitory synaptic transmission to retinal ganglion cells.In the present study,we used the patch-clamp technique to recordγ-aminobutyric acid subtype A receptor-mediated miniature inhibitory postsynaptic currents in retinal ganglion cells from streptozotocin-induced diabetes model rats.We found that early diabetes(4 weeks of hyperglycemia)decreased the frequency of GABAergic miniature inhibitory postsynaptic currents in retinal ganglion cells without altering their amplitude,suggesting a reduction in the spontaneous release ofγ-aminobutyric acid to retinal ganglion cells.Topical administration of glucagon-like peptide-1 eyedrops over a period of 2 weeks effectively countered the hyperglycemia-induced downregulation of GABAergic mIPSC frequency,subsequently enhancing the survival of retinal ganglion cells.Concurrently,the protective effects of glucagon-like peptide-1 on retinal ganglion cells in diabetic rats were eliminated by topical administration of exendin-9-39,a specific glucagon-like peptide-1 receptor antagonist,or SR95531,a specific antagonist of theγ-aminobutyric acid subtype A receptor.Furthermore,extracellular perfusion of glucagon-like peptide-1 was found to elevate the frequencies of GABAergic miniature inhibitory postsynaptic currents in both ON-and OFF-type retinal ganglion cells.This elevation was shown to be mediated by activation of the phosphatidylinositol-phospholipase C/inositol 1,4,5-trisphosphate receptor/Ca2+/protein kinase C signaling pathway downstream of glucagon-like peptide-1 receptor activation.Moreover,multielectrode array recordings revealed that glucagon-like peptide-1 functionally augmented the photoresponses of ON-type retinal ganglion cells.Optomotor response tests demonstrated that diabetic rats exhibited reductions in visual acuity and contrast sensitivity that were significantly ameliorated by topical administration of glucagon-like peptide-1.These results suggest that glucagon-like peptide-1 facilitates the release ofγ-aminobutyric acid onto retinal ganglion cells through the activation of glucagon-like peptide-1 receptor,leading to the de-excitation of retinal ganglion cell circuits and the inhibition of excitotoxic processes associated with diabetic retinopathy.Collectively,our findings indicate that theγ-aminobutyric acid system has potential as a therapeutic target for mitigating early-stage diabetic retinopathy.Furthermore,the topical administration of glucagon-like peptide-1 eyedrops represents a non-invasive and effective treatment approach for managing early-stage diabetic retinopathy.展开更多
目的分析一体式蜗内耳蜗电图在人工耳蜗植入(CI)术中的应用情况,讨论其优势及局限,总结该技术的标准化流程。方法收集2023年3月~2025年8月于本团队实施人工耳蜗术中一体式蜗内耳蜗电图的全部临床资料及术中监测数据,对监测成功率、监测...目的分析一体式蜗内耳蜗电图在人工耳蜗植入(CI)术中的应用情况,讨论其优势及局限,总结该技术的标准化流程。方法收集2023年3月~2025年8月于本团队实施人工耳蜗术中一体式蜗内耳蜗电图的全部临床资料及术中监测数据,对监测成功率、监测指标变化规律等进行分析,建立术中监测三阶段分型(植入早期、中期和晚期;上升型、下降型、稳定型、波动型)。结果共有44例(45耳)患者应用该技术(男24,女20),平均年龄27.3±19.2岁,术前低频平均听力为86.6±21.1 dB HL,无明显的耳蜗畸形,均完成全部电极植入。15耳成功在术中引出CM波形,9耳于术毕或术后第2天引出波形,21耳未引出波形(其中9耳术中干扰严重,2耳术中耳机脱落)。在去除术中干扰严重的9耳和术中耳机脱落的2耳后,34耳的术中CM波形引出率与术前低频平均听力之间无统计学意义(n=34,χ^(2)=1.145,P=0.451),且该34耳以及术中成功引出15耳耳蜗微音电位(cochlear microphonics,CM)波形最大幅值与术前低频平均听力无明显相关(n=34,r=-0.015,P=0.931;n=15,r=0.237,P=0.395)。15耳中,植入早期最常见为波动型[7耳(46.7%)],其中4耳依据波形变化采用优化植入干预方案;在中期为稳定型和波动型居多[均为5耳(33.3%)];在晚期,各类型比例相近,且波形下降趋势难以通过干预方案得到恢复。在本院完成术后开机随访且具有术前可测听力的12例(12耳)患者,术后低频听力完全保留率为75%,部分保留率为25%。术毕/术中最高幅值比与术后低频听力阈移呈显著负相关(r=-0.707,P=0.01)。结论术中应用ECochG技术可实时反馈电极植入对内耳的创伤,及时在损伤可逆期内进行微创化调整,有助于术后残余听力的保留。术中标准化流程的建立有助于提升该技术的术中引出率。术中监测三阶段分型的建立有助于电极植入对内耳创伤的机制分析。术中CM波形引出率、引出幅值与术前低频平均听力的关系仍待进一步探讨分析。展开更多
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(Nos.2019R1A2C1002221 and RS-2023-00252186)Institute of Information&Communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(Nos.2021-0-00590,RS-2021-II210590Decentralized High Performance Consensus for Large-Scale Blockchains).
文摘Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. However, standalone PVRs are limited by their individual storage capacities, restricting the number of programs they can store. While online catch-up TV services such as Hulu and Netflix mitigate this limitation by offering on-demand access to broadcast programs shortly after their initial broadcast, they require substantial storage and network resources, leading to significant infrastructural costs for service providers. To address these challenges, we propose a collaborative TV content recording system that leverages distributed PVRs, combining their storage into a virtual shared pool without additional costs. Our system aims to support all concurrent playback requests without service interruption while ensuring program availability comparable to that of local devices. The main contributions of our proposed system are fourfold. First, by sharing storage and upload bandwidth among PVRs, our system significantly expands the overall recording capacity and enables simultaneous recording of multiple programs without the physical constraints of standalone devices. Second, by utilizing erasure coding efficiently, our system reduces the storage space required for each program, allowing more programs to be recorded compared to traditional replication. Third, we propose an adaptive redundancy scheme to control the degree of redundancy of each program based on its evolving playback demand, ensuring high-quality playback by providing sufficient bandwidth for popular programs. Finally, we introduce a contribution-based incentive policy that encourages PVRs to actively participate by contributing resources, while discouraging excessive consumption of the combined storage pool. Through extensive experiments, we demonstrate the effectiveness of our proposed collaborative TV program recording system in terms of storage efficiency and performance.
基金supported by the National Key R&D Program of China under Grant 2018YFA0701400 and 2018YFA0701401.
文摘This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(SAR ADC) is shared among all 20 channels. A charge-sharing multiplexer(MUX) is proposed to transmit the output signals from the respective channels to the ADC. By separately pre sampling the output of each channel, the sampling time of each channel is greatly extended and additional active buffers are avoided. The AFE is fabricated in a 65-nm CMOS process, and the whole system consumes 28.2 μW under 1 V supply. Each analog acquisition channel consumes 1.25 μW and occupies a chip area of 0.14 mm2. Measurement results show that the AFE achieves an input referred noise of 1.8 μV·rms in a 350 Hz bandwidth and a noise efficiency factor(NEF) of 4.1. The 12-bit SAR ADC achieves an ENOB of 9.8 bit operating at 25 k S/s. The AFE is experimented on real-world applications by measuring human ECG and a clear ECG waveform is captured.
文摘通过野外调查、标本鉴定及文献查阅,发现陕西省被子植物分布新记录8种,分别为神农架铁线莲(Clematis shenlungchiaensis M.Y.Fang)、南川景天(Sedum rosthornianum Diels)、皱叶雀梅藤(Sageretia rugosa Hance)、盐芥〔Eutrema salsugineum(Pall.)Al-Shehbaz et Warwick〕、神农架蓼(Koenigia hedbergii Bo Li et W.Du)、薄叶新耳草〔Neanotis hirsuta(Linn.f.)W.H.Lewis〕、水蓑衣〔Hygrophila ringens(Linn.)R.Brown ex Spreng.〕、水蜡烛〔Pogostemon yatabeanus(Makino)Press〕。此外,新耳草属(Neanotis W.H.Lewis)、水蓑衣属(Hygrophila R.Br.)和刺蕊草属(Pogostemon Desf.)为陕西省新记录属。
文摘The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “onozuka” R\|10, 0\^01% pectolyase Y\|23,0\^15% macerozyme R\|10 and 0\^1% hemicellulase at 25℃. Outward and inward single channels in plasma membrane were observed using cell\|attached recording of patch\|clamp technique. In this study, single channel records showed that more than one species of channel were obtained. These attempts in protoplast isolation and ion channel recording offers the opportunity to characterize cellular mechanisms of salt tolerance in tree species.
基金The National Natural Science Foundation of China(No. 61076118, 90307013, 90707005)the Natural Science Foundation of Jiangsu Province (No. BK2008032)Special Foundation and Open Foundation of the State Key Laboratory of Bioelectronics of Southeast University
文摘A microelectrode array(MEA) is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair consists of one stimulating electrode and one recording electrode. Supported by the peripheral circuits, four electrode states to study the bioelectrical signal of biological tissue or slice cultured in-vitro on the surface of the electrodes can be realized through each pair of electrodes. The four electrode states are stimulation, recording, stimulation and recording simultaneously, and isolation. The state of each pair of working electrodes can be arbitrarily controlled according to actual needs. The MEAs are fabricated in printed circuit board (PCB) technology. The total area of the PCB-based MEA is 49 mm × 49 mm. The impedance measurement of MEA is carried out in 0.9% sodium chloride solution at room temperature by means of 2-point measurements with an Agilent LCR meter, and the test signal for the impedance measurement is sinusoidal (AC voltage 50 mV, sweeping frequency 20 Hz to 10 kHz). The electrode impedance is between 200 and 3 kΩ while the frequency is between 500 and 1 000 Hz. The electrode impedance magnitude is inversely proportional to the frequency. Experiments of toad sciatic nerve in-vitro stimulation and recording and signal regeneration between isolated toad sciatic nerves are carried out on the PCB-based MEA. The results show that the MEA can be used for bioelectrical signal stimulation, recording, stimulation and recording simultaneously, and isolation of biological tissues or slices in-vitro.
文摘In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location method for extra high voltage and long distance transmission lines.
文摘Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a (hASIC1a) current in HEK293 cells with a modified perfusion methods. Methods With cell floating method, which is separating the cultured cell from coverslip and putting the cell in front of perfusion tubing, whole cell patch clamp technique was used to record hASICla currents evoked by low pH external solution. Results Using cell floating method, the amplitude of hASICla currents activated by pH 5.0 in HEK293 cells is twice as large as that by the conventional method where the cells remain attached to coverslip. The time to reach peak at two different recording conditions is (21±5) ms and (270±25) ms, respectively. Inactivation time constants are (496±23) ms and (2284±120) ms, respectively. The cell floating method significantly increases the amiloride potency of block on hASIC 1 a [IC50 is (3.4± 1.1 ) μmol/L and (2.4± 0.9) μmol/L, respectively]. Both recording methods have similar pH activation ECs0 (6.6±0.6, 6.6±0.7, respectively). Conclusion ASICs channel activation requires fast exchange of extracellular solution with the different pH values. With cell floating method, the presence of hASIC la current was re-confirmed and the biophysical and pharmacological properties of hASIC la channel in HEK293 cells was precisely characterized. This method could be used to study all ASICs and other ligand-gated channels that require fast extracellular solution exchange.
基金supported by the National Natural Science Foundation of China,Nos.32070989(to YMZ),31872766(to YMZ),81790640(to XLY),and 82070993(to SJW)the grant from Sanming Project of Medicine in Shenzhen,No.SZSM202011015(to XLY)。
文摘Diabetic retinopathy is a prominent cause of blindness in adults,with early retinal ganglion cell loss contributing to visual dysfunction or blindness.In the brain,defects inγ-aminobutyric acid synaptic transmission are associated with pathophysiological and neurodegenerative disorders,whereas glucagon-like peptide-1 has demonstrated neuroprotective effects.However,it is not yet clear whether diabetes causes alterations in inhibitory input to retinal ganglion cells and whether and how glucagon-like peptide-1 protects against neurodegeneration in the diabetic retina through regulating inhibitory synaptic transmission to retinal ganglion cells.In the present study,we used the patch-clamp technique to recordγ-aminobutyric acid subtype A receptor-mediated miniature inhibitory postsynaptic currents in retinal ganglion cells from streptozotocin-induced diabetes model rats.We found that early diabetes(4 weeks of hyperglycemia)decreased the frequency of GABAergic miniature inhibitory postsynaptic currents in retinal ganglion cells without altering their amplitude,suggesting a reduction in the spontaneous release ofγ-aminobutyric acid to retinal ganglion cells.Topical administration of glucagon-like peptide-1 eyedrops over a period of 2 weeks effectively countered the hyperglycemia-induced downregulation of GABAergic mIPSC frequency,subsequently enhancing the survival of retinal ganglion cells.Concurrently,the protective effects of glucagon-like peptide-1 on retinal ganglion cells in diabetic rats were eliminated by topical administration of exendin-9-39,a specific glucagon-like peptide-1 receptor antagonist,or SR95531,a specific antagonist of theγ-aminobutyric acid subtype A receptor.Furthermore,extracellular perfusion of glucagon-like peptide-1 was found to elevate the frequencies of GABAergic miniature inhibitory postsynaptic currents in both ON-and OFF-type retinal ganglion cells.This elevation was shown to be mediated by activation of the phosphatidylinositol-phospholipase C/inositol 1,4,5-trisphosphate receptor/Ca2+/protein kinase C signaling pathway downstream of glucagon-like peptide-1 receptor activation.Moreover,multielectrode array recordings revealed that glucagon-like peptide-1 functionally augmented the photoresponses of ON-type retinal ganglion cells.Optomotor response tests demonstrated that diabetic rats exhibited reductions in visual acuity and contrast sensitivity that were significantly ameliorated by topical administration of glucagon-like peptide-1.These results suggest that glucagon-like peptide-1 facilitates the release ofγ-aminobutyric acid onto retinal ganglion cells through the activation of glucagon-like peptide-1 receptor,leading to the de-excitation of retinal ganglion cell circuits and the inhibition of excitotoxic processes associated with diabetic retinopathy.Collectively,our findings indicate that theγ-aminobutyric acid system has potential as a therapeutic target for mitigating early-stage diabetic retinopathy.Furthermore,the topical administration of glucagon-like peptide-1 eyedrops represents a non-invasive and effective treatment approach for managing early-stage diabetic retinopathy.
文摘目的分析一体式蜗内耳蜗电图在人工耳蜗植入(CI)术中的应用情况,讨论其优势及局限,总结该技术的标准化流程。方法收集2023年3月~2025年8月于本团队实施人工耳蜗术中一体式蜗内耳蜗电图的全部临床资料及术中监测数据,对监测成功率、监测指标变化规律等进行分析,建立术中监测三阶段分型(植入早期、中期和晚期;上升型、下降型、稳定型、波动型)。结果共有44例(45耳)患者应用该技术(男24,女20),平均年龄27.3±19.2岁,术前低频平均听力为86.6±21.1 dB HL,无明显的耳蜗畸形,均完成全部电极植入。15耳成功在术中引出CM波形,9耳于术毕或术后第2天引出波形,21耳未引出波形(其中9耳术中干扰严重,2耳术中耳机脱落)。在去除术中干扰严重的9耳和术中耳机脱落的2耳后,34耳的术中CM波形引出率与术前低频平均听力之间无统计学意义(n=34,χ^(2)=1.145,P=0.451),且该34耳以及术中成功引出15耳耳蜗微音电位(cochlear microphonics,CM)波形最大幅值与术前低频平均听力无明显相关(n=34,r=-0.015,P=0.931;n=15,r=0.237,P=0.395)。15耳中,植入早期最常见为波动型[7耳(46.7%)],其中4耳依据波形变化采用优化植入干预方案;在中期为稳定型和波动型居多[均为5耳(33.3%)];在晚期,各类型比例相近,且波形下降趋势难以通过干预方案得到恢复。在本院完成术后开机随访且具有术前可测听力的12例(12耳)患者,术后低频听力完全保留率为75%,部分保留率为25%。术毕/术中最高幅值比与术后低频听力阈移呈显著负相关(r=-0.707,P=0.01)。结论术中应用ECochG技术可实时反馈电极植入对内耳的创伤,及时在损伤可逆期内进行微创化调整,有助于术后残余听力的保留。术中标准化流程的建立有助于提升该技术的术中引出率。术中监测三阶段分型的建立有助于电极植入对内耳创伤的机制分析。术中CM波形引出率、引出幅值与术前低频平均听力的关系仍待进一步探讨分析。