Based on the remote sensing images of algae, the present work analyzes the horizontal distribution characteristics of algal blooms in Chaohu Lake, China, which also reveals the frequency of algal blooms under differen...Based on the remote sensing images of algae, the present work analyzes the horizontal distribution characteristics of algal blooms in Chaohu Lake, China, which also reveals the frequency of algal blooms under different wind directions. Further, an unstructured-grid, three-dimensional finite-volume coastal ocean model （FVCOM） is applied to investigate the wind-induced currents and the transport pro- cess to explain the reason why algal blooms occur at the detected places. We first deduce the primary distribution of biomass from overlaid satellite images, and explain the formation mechanism by analyzing the pollution sources, and simulating the flow field and transportation process under prevailing wind over Chaohu Lake. And then, we consider the adjustment action of the wind on the corresponding day and develop a two-time scale approach to describe the whole formation process of algae horizontal distribution in Chaohu Lake. That is, on the longer time scale, i.e., during bloom season, prevailing wind determines the primary distribution of biomass by inducing the characteristic flow field; on the shorter time scale, i.e., on the day when bloom occurs, the wind force adjusts the primary distribution of biomass to form the final distribution of algal bloom.展开更多
Alarm flood is one of the main problems in the alarm systems of industrial process. Alarm root-cause analysis and alarm prioritization are good for alarm flood reduction. This paper proposes a systematic rationalizati...Alarm flood is one of the main problems in the alarm systems of industrial process. Alarm root-cause analysis and alarm prioritization are good for alarm flood reduction. This paper proposes a systematic rationalization method for multivariate correlated alarms to realize the root cause analysis and alarm prioritization. An information fusion based interpretive structural model is constructed according to the data-driven partial correlation coefficient calculation and process knowledge modification. This hierarchical multi-layer model is helpful in abnormality propagation path identification and root-cause analysis. Revised Likert scale method is adopted to determine the alarm priority and reduce the blindness of alarm handling. As a case study, the Tennessee Eastman process is utilized to show the effectiveness and validity of proposed approach. Alarm system performance comparison shows that our rationalization methodology can reduce the alarm flood to some extent and improve the performance.展开更多
The recent GMP （good medical practice） rules actualisation and its requirements introduction widened the GMP guidelines for every life cycle of medicinal products, including the stage of processes scaling and techno...The recent GMP （good medical practice） rules actualisation and its requirements introduction widened the GMP guidelines for every life cycle of medicinal products, including the stage of processes scaling and technology transfer. This requires the technology transfer process to be regulated as the part of pharmaceutical quality system and the following development of corresponding written procedures. The following publication is dedicated to the development of TTP （technology transfer process） and its accessible graphic formalisation alongside the definition of main stages and possible procedures limited by the offered model. According to the actualized GMP rules, the technology transfer is an essential part of pharmaceutical quality system at a modem pharmaceutical company.展开更多
Nanometallic materials have attracted wide research attention in the fabrication of functional devices,including flexible electronics circuits and high-sensitive sensors.Sintering of nanometallic materials is generall...Nanometallic materials have attracted wide research attention in the fabrication of functional devices,including flexible electronics circuits and high-sensitive sensors.Sintering of nanometallic materials is generally thought as an effective technology for the functional manufacturing,and the controllable sintering of nanometallic materials and its major mechanisms have long been a challenge.Here,an ultrafast laser processing strategy for Ag nanoparticles(NPs)is achieved by modulating plasmonic.The excitation mode of plasmon can be designed by laser parameters,including polarization with a specific crystal size.The atomic-scale ultrafast dynamics are revealed for understanding the sintering process and design of the sintered structures.The non-equilibrium energy transfer between electron and lattice and dynamic evolution of pressure are proved to be the foremost driving forces on the motion of atomic structures.Through research of plasmonic-induced electric field enhancement and non-uniform deposition of heat and in-situ observation of relative transmittance,mapping from atomic-scale structure to micro behavior is established.Based on plasmonic modulation and processing of Ag NPs,a machine learning combined flexible gesture sensor with high recognition accuracy is displayed.This work expands the knowledge of interactions between lasers and nanometallic materials and provides a method for designing functional devices for a wide range of applications.展开更多
近年来,碳捕集、利用与封存(carbon capture utilization and storage,CCUS)技术在减少CO_(2)排放方面取得了显著进展,但其高能耗和复杂的工艺流程限制了大规模推广应用。为提升能源利用效率,集成二氧化碳捕集与利用(integrated CO_(2)c...近年来,碳捕集、利用与封存(carbon capture utilization and storage,CCUS)技术在减少CO_(2)排放方面取得了显著进展,但其高能耗和复杂的工艺流程限制了大规模推广应用。为提升能源利用效率,集成二氧化碳捕集与利用(integrated CO_(2)capture and utilization,ICCU)技术逐渐成为研究的重点方向,该技术通过双功能材料(dual-functional materials,DFM)实现CO_(2)的捕集与原位转化,直接将捕集的CO_(2)高效转化为具有经济价值的化学品。与传统CCU技术相比,ICCU技术大幅简化了CO_(2)解吸、压缩和运输等步骤,具有广阔的应用潜力。围绕ICCU-甲烷化(ICCU-Methanation,ICCU-Met)技术,首先系统介绍了ICCU-Met过程并从热力学角度分析了该技术实现CO_(2)捕集与转化的可行性;随后重点探讨了应用于该过程的双功能材料,分析了其在CO_(2)捕集能力、催化活性、稳定性等方面的表现;并针对ICCU-Met技术面临的过程放大挑战,分析了实际工业烟气条件、反应器设计及技术经济性等方面的问题;最后总结了该技术的发展瓶颈,并提出了未来可能的研究方向。展开更多
Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00197-w In the original article,the author name‘Emmanuel Olusola Oke’was given incorrectly as'Olushola E.Oke'.The origi...Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00197-w In the original article,the author name‘Emmanuel Olusola Oke’was given incorrectly as'Olushola E.Oke'.The origi-nal article has been corrected.展开更多
基金supported by the Hundred Talents Program of Chinese Academy of Sciencesthe National Natural Science Fundation of China for Distinguished Young Scholar(10825211)
文摘Based on the remote sensing images of algae, the present work analyzes the horizontal distribution characteristics of algal blooms in Chaohu Lake, China, which also reveals the frequency of algal blooms under different wind directions. Further, an unstructured-grid, three-dimensional finite-volume coastal ocean model （FVCOM） is applied to investigate the wind-induced currents and the transport pro- cess to explain the reason why algal blooms occur at the detected places. We first deduce the primary distribution of biomass from overlaid satellite images, and explain the formation mechanism by analyzing the pollution sources, and simulating the flow field and transportation process under prevailing wind over Chaohu Lake. And then, we consider the adjustment action of the wind on the corresponding day and develop a two-time scale approach to describe the whole formation process of algae horizontal distribution in Chaohu Lake. That is, on the longer time scale, i.e., during bloom season, prevailing wind determines the primary distribution of biomass by inducing the characteristic flow field; on the shorter time scale, i.e., on the day when bloom occurs, the wind force adjusts the primary distribution of biomass to form the final distribution of algal bloom.
基金Supported by the National Natural Science Foundation of China(61473026,61104131)the Fundamental Research Funds for the Central Universities(JD1413)
文摘Alarm flood is one of the main problems in the alarm systems of industrial process. Alarm root-cause analysis and alarm prioritization are good for alarm flood reduction. This paper proposes a systematic rationalization method for multivariate correlated alarms to realize the root cause analysis and alarm prioritization. An information fusion based interpretive structural model is constructed according to the data-driven partial correlation coefficient calculation and process knowledge modification. This hierarchical multi-layer model is helpful in abnormality propagation path identification and root-cause analysis. Revised Likert scale method is adopted to determine the alarm priority and reduce the blindness of alarm handling. As a case study, the Tennessee Eastman process is utilized to show the effectiveness and validity of proposed approach. Alarm system performance comparison shows that our rationalization methodology can reduce the alarm flood to some extent and improve the performance.
文摘The recent GMP （good medical practice） rules actualisation and its requirements introduction widened the GMP guidelines for every life cycle of medicinal products, including the stage of processes scaling and technology transfer. This requires the technology transfer process to be regulated as the part of pharmaceutical quality system and the following development of corresponding written procedures. The following publication is dedicated to the development of TTP （technology transfer process） and its accessible graphic formalisation alongside the definition of main stages and possible procedures limited by the offered model. According to the actualized GMP rules, the technology transfer is an essential part of pharmaceutical quality system at a modem pharmaceutical company.
基金supported by the National Natural Science Foundation of China(52575510)the National Key R&D Program of China(2024YFB4609801).
文摘Nanometallic materials have attracted wide research attention in the fabrication of functional devices,including flexible electronics circuits and high-sensitive sensors.Sintering of nanometallic materials is generally thought as an effective technology for the functional manufacturing,and the controllable sintering of nanometallic materials and its major mechanisms have long been a challenge.Here,an ultrafast laser processing strategy for Ag nanoparticles(NPs)is achieved by modulating plasmonic.The excitation mode of plasmon can be designed by laser parameters,including polarization with a specific crystal size.The atomic-scale ultrafast dynamics are revealed for understanding the sintering process and design of the sintered structures.The non-equilibrium energy transfer between electron and lattice and dynamic evolution of pressure are proved to be the foremost driving forces on the motion of atomic structures.Through research of plasmonic-induced electric field enhancement and non-uniform deposition of heat and in-situ observation of relative transmittance,mapping from atomic-scale structure to micro behavior is established.Based on plasmonic modulation and processing of Ag NPs,a machine learning combined flexible gesture sensor with high recognition accuracy is displayed.This work expands the knowledge of interactions between lasers and nanometallic materials and provides a method for designing functional devices for a wide range of applications.
文摘近年来,碳捕集、利用与封存(carbon capture utilization and storage,CCUS)技术在减少CO_(2)排放方面取得了显著进展,但其高能耗和复杂的工艺流程限制了大规模推广应用。为提升能源利用效率,集成二氧化碳捕集与利用(integrated CO_(2)capture and utilization,ICCU)技术逐渐成为研究的重点方向,该技术通过双功能材料(dual-functional materials,DFM)实现CO_(2)的捕集与原位转化,直接将捕集的CO_(2)高效转化为具有经济价值的化学品。与传统CCU技术相比,ICCU技术大幅简化了CO_(2)解吸、压缩和运输等步骤,具有广阔的应用潜力。围绕ICCU-甲烷化(ICCU-Methanation,ICCU-Met)技术,首先系统介绍了ICCU-Met过程并从热力学角度分析了该技术实现CO_(2)捕集与转化的可行性;随后重点探讨了应用于该过程的双功能材料,分析了其在CO_(2)捕集能力、催化活性、稳定性等方面的表现;并针对ICCU-Met技术面临的过程放大挑战,分析了实际工业烟气条件、反应器设计及技术经济性等方面的问题;最后总结了该技术的发展瓶颈,并提出了未来可能的研究方向。
文摘Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00197-w In the original article,the author name‘Emmanuel Olusola Oke’was given incorrectly as'Olushola E.Oke'.The origi-nal article has been corrected.
