中国糖尿病患病率不断攀升,患者超2.33亿,然而,针对心血管疾病和癌症等糖尿病并发症的本土研究缺失。中国心血管代谢与恶性肿瘤队列研究[China Cardiometabolic Disease and Cancer Cohort(4C)Study](基线调查于2011—2012年开展,最新...中国糖尿病患病率不断攀升,患者超2.33亿,然而,针对心血管疾病和癌症等糖尿病并发症的本土研究缺失。中国心血管代谢与恶性肿瘤队列研究[China Cardiometabolic Disease and Cancer Cohort(4C)Study](基线调查于2011—2012年开展,最新随访至2024年)首次系统揭示中国糖尿病患者多种糖尿病并发症结局规律,填补循证空白。本文综述了4C研究的背景、研究方法、研究结果、学术影响和争议,指出了未来的挑战和策略。展开更多
The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solutio...The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solution were used to regulate the microstructure,mechanical properties,and corrosion properties of B_(4)C/TC4 composite.Results show that with the increase in temperature from 500℃to 800°C,partial lamellarα-Ti in the as-deposited sample is gradually transformed into equiaxedα-Ti,accompanied by the disappearance of basketweave microstructure.At 1100°C,a small portion of TiC phase suffers fusion.This composite exhibits the optimal combination of strength and plasticity after annealing at 500℃for 4 h followed by furnace cooling,which is attributed to the stress release effect and the refined basketweave microstructure.However,this composite shows a decline in corrosion resistance after various heat treatments due to grain coarsening and micro-galvanic corrosion.展开更多
文摘中国糖尿病患病率不断攀升,患者超2.33亿,然而,针对心血管疾病和癌症等糖尿病并发症的本土研究缺失。中国心血管代谢与恶性肿瘤队列研究[China Cardiometabolic Disease and Cancer Cohort(4C)Study](基线调查于2011—2012年开展,最新随访至2024年)首次系统揭示中国糖尿病患者多种糖尿病并发症结局规律,填补循证空白。本文综述了4C研究的背景、研究方法、研究结果、学术影响和争议,指出了未来的挑战和策略。
基金Tianjin Municipal Natural Science Foundation(23JCYBJC00040)National Natural Science Foundation of China(52175369)。
文摘The TiB+TiC dual-reinforced B_(4)C/TC4 composite was in-situ fabricated via incorporating 0.5wt%B_(4)C reinforcement during the laser melting deposition process.Different heat treatments of annealing and solid solution were used to regulate the microstructure,mechanical properties,and corrosion properties of B_(4)C/TC4 composite.Results show that with the increase in temperature from 500℃to 800°C,partial lamellarα-Ti in the as-deposited sample is gradually transformed into equiaxedα-Ti,accompanied by the disappearance of basketweave microstructure.At 1100°C,a small portion of TiC phase suffers fusion.This composite exhibits the optimal combination of strength and plasticity after annealing at 500℃for 4 h followed by furnace cooling,which is attributed to the stress release effect and the refined basketweave microstructure.However,this composite shows a decline in corrosion resistance after various heat treatments due to grain coarsening and micro-galvanic corrosion.
