Powdery mildew, which called Sphaerotheca phaseoli in Latin, is one of the major diseases of mungbean （Vigna radiata L.） worldwide, causing up to 50% yield losses. Most mungbean varieties grown in Thailand are susce...Powdery mildew, which called Sphaerotheca phaseoli in Latin, is one of the major diseases of mungbean （Vigna radiata L.） worldwide, causing up to 50% yield losses. Most mungbean varieties grown in Thailand are susceptible to the disease, therefore, new resistant varieties are highly desirable. Three resistant mungbean lines, V4718, V4758 and V4785, were identified from the AVRDC collection. In this study, the authors compared the resistance levels among these 3 lines and tested the allelic relationship among these resistance genes. Three crosses, V4718 × V4758, V4718 × V4785 and V4758 × V4785, were made and the F1 hybrids were selfed to generate the F2 populations and crossed to a susceptible variety, CN72 to generate the F1 × S populations. In the F1 × S and F2 populations, the resistance segregated in a ratio of 3 Resistant （R）：I Susceptible （S） and 15R：IS, respectively for all three crosses. These results indicate that a single dominant gene confers resistance to powdery mildew in each resistant line and these resistance genes are non-allelic. The authors are currently transferring these resistance genes into commercial varieties to provide durable resistance to powdery mildew.展开更多
目的:观察麻黄连翘赤小豆汤加减治疗湿热咳嗽的临床疗效及其对患者临床症状评分及炎症反应的影响。方法:将136例湿热咳嗽患者按照随机数字表法分为对照组和观察组,每组各68例。对照组给予常规治疗,观察组在对照组治疗的基础上加用麻黄...目的:观察麻黄连翘赤小豆汤加减治疗湿热咳嗽的临床疗效及其对患者临床症状评分及炎症反应的影响。方法:将136例湿热咳嗽患者按照随机数字表法分为对照组和观察组,每组各68例。对照组给予常规治疗,观察组在对照组治疗的基础上加用麻黄连翘赤小豆汤加减。比较两组患者的临床疗效及治疗前后临床症状评分、生活质量综合评定问卷-74(generic quality of life inventory-74,GQOLI-74)评分变化情况,采用酶联免疫法检测两组患者治疗前后肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-6(interleukin-6,IL-6)、超敏C反应蛋白(hs-C reactive protein, hs-CRP)及白细胞介素-8(interleukin-8,IL-8)。结果:观察组有效率为95.59%,对照组有效率为83.82%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后咳嗽、咳痰、饮食、大便、小便、睡眠等临床症状评分低于本组治疗前,且观察组低于对照组(P<0.05)。两组患者治疗后TNF-α、IL-6、IL-8、hs-CRP水平低于本组治疗前,且治疗后观察组低于对照组(P<0.05)。两组患者治疗后GQOLI-74评分高于本组治疗前,且治疗后观察组高于对照组(P<0.05)。结论:麻黄连翘赤小豆汤加减治疗湿热咳嗽,可缓解患者的临床症状,减轻炎症反应,提高生活质量。展开更多
文摘Powdery mildew, which called Sphaerotheca phaseoli in Latin, is one of the major diseases of mungbean （Vigna radiata L.） worldwide, causing up to 50% yield losses. Most mungbean varieties grown in Thailand are susceptible to the disease, therefore, new resistant varieties are highly desirable. Three resistant mungbean lines, V4718, V4758 and V4785, were identified from the AVRDC collection. In this study, the authors compared the resistance levels among these 3 lines and tested the allelic relationship among these resistance genes. Three crosses, V4718 × V4758, V4718 × V4785 and V4758 × V4785, were made and the F1 hybrids were selfed to generate the F2 populations and crossed to a susceptible variety, CN72 to generate the F1 × S populations. In the F1 × S and F2 populations, the resistance segregated in a ratio of 3 Resistant （R）：I Susceptible （S） and 15R：IS, respectively for all three crosses. These results indicate that a single dominant gene confers resistance to powdery mildew in each resistant line and these resistance genes are non-allelic. The authors are currently transferring these resistance genes into commercial varieties to provide durable resistance to powdery mildew.
文摘目的:观察麻黄连翘赤小豆汤加减治疗湿热咳嗽的临床疗效及其对患者临床症状评分及炎症反应的影响。方法:将136例湿热咳嗽患者按照随机数字表法分为对照组和观察组,每组各68例。对照组给予常规治疗,观察组在对照组治疗的基础上加用麻黄连翘赤小豆汤加减。比较两组患者的临床疗效及治疗前后临床症状评分、生活质量综合评定问卷-74(generic quality of life inventory-74,GQOLI-74)评分变化情况,采用酶联免疫法检测两组患者治疗前后肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-6(interleukin-6,IL-6)、超敏C反应蛋白(hs-C reactive protein, hs-CRP)及白细胞介素-8(interleukin-8,IL-8)。结果:观察组有效率为95.59%,对照组有效率为83.82%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后咳嗽、咳痰、饮食、大便、小便、睡眠等临床症状评分低于本组治疗前,且观察组低于对照组(P<0.05)。两组患者治疗后TNF-α、IL-6、IL-8、hs-CRP水平低于本组治疗前,且治疗后观察组低于对照组(P<0.05)。两组患者治疗后GQOLI-74评分高于本组治疗前,且治疗后观察组高于对照组(P<0.05)。结论:麻黄连翘赤小豆汤加减治疗湿热咳嗽,可缓解患者的临床症状,减轻炎症反应,提高生活质量。
