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Using SVM to construct a Chinese dependency parser 被引量:1
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作者 许云 张锋 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2006年第2期199-203,共5页
In Chinese, dependency analysis has been shown to be a powerful syntactic parser because the order of phrases in a sentence is relatively free compared with English. Conventional dependency parsers require a number of... In Chinese, dependency analysis has been shown to be a powerful syntactic parser because the order of phrases in a sentence is relatively free compared with English. Conventional dependency parsers require a number of sophisticated rules that have to be handcrafted by linguists, and are too cumbersome to maintain. To solve the problem, a parser using SVM (Support Vector Machine) is introduced. First, a new strategy of dependency analysis is proposed. Then some chosen feature types are used for learning and for creating the modification matrix using SVM. Finally, the dependency of phrases in the sentence is generated. Experiments conducted to analyze how each type of feature affects parsing accuracy, showed that the model can increase accuracy of the dependency parser by 9.2%. 展开更多
关键词 Syntactic parsing DEPENDENCY Support Vector Machine (SVM)
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An Efficient Way to Parse Logs Automatically for Multiline Events
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作者 Mingguang Yu Xia Zhang 《Computer Systems Science & Engineering》 SCIE EI 2023年第9期2975-2994,共20页
In order to obtain information or discover knowledge from system logs,the first step is to performlog parsing,whereby unstructured raw logs can be transformed into a sequence of structured events.Although comprehensiv... In order to obtain information or discover knowledge from system logs,the first step is to performlog parsing,whereby unstructured raw logs can be transformed into a sequence of structured events.Although comprehensive studies on log parsing have been conducted in recent years,most assume that one event object corresponds to a single-line message.However,in a growing number of scenarios,one event object spans multiple lines in the log,for which parsing methods toward single-line events are not applicable.In order to address this problem,this paper proposes an automated log parsing method for multiline events(LPME).LPME finds multiline event objects via iterative scanning,driven by a set of heuristic rules derived from practice.The advantage of LPME is that it proposes a cohesion-based evaluation method for multiline events and a bottom-up search approach that eliminates the process of enumerating all combinations.We analyze the algorithmic complexity of LPME and validate it on four datasets from different backgrounds.Evaluations show that the actual time complexity of LPME parsing for multiline events is close to the constant time,which enables it to handle large-scale sample inputs.On the experimental datasets,the performance of LPME achieves 1.0 for recall,and the precision is generally higher than 0.9,which demonstrates the effectiveness of the proposed LPME. 展开更多
关键词 Log parsing log management log analysis system maintenance
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Linear algorithm for lexicographic enumeration of CFG parse trees 被引量:2
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作者 DONG YunMei 《Science in China(Series F)》 2009年第7期1177-1202,共26页
We study CFG parse tree enumeration in this paper. By dividing the set of all parse trees into infinite hierarchies according to height of parse tree, the hierarchical lexicographic order on the set of parse trees is ... We study CFG parse tree enumeration in this paper. By dividing the set of all parse trees into infinite hierarchies according to height of parse tree, the hierarchical lexicographic order on the set of parse trees is established. Then grammar-based algorithms for counting and enumerating CFG parse trees in this order are presented. To generate a parse tree of height n, the time complexity is O(n). If τ is a lowest parse tree for its yield, then O(n) =O(||τ|| + 1), where ||τ|| is the length of the sentence (yield) generated by τ. The sentence can be obtained as a by-product of the parse tree. To compute sentence from its parse tree (needn't be lowest one), the time complexity is O(node)+O(||τ|| + 1), where node is the number of non-leaf nodes of parse tree τ. To generate both a complete lowest parse tree and its yield at the same time, the time complexity is O(||τ|| + 1). 展开更多
关键词 hierarchical construction of set of parse trees lexicographic enumeration of parse trees counting of parse trees
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Kernel-Based Semantic Relation Detection and Classification via Enriched Parse Tree Structure 被引量:7
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作者 周国栋 朱巧明 《Journal of Computer Science & Technology》 SCIE EI CSCD 2011年第1期45-56,共12页
This paper proposes a tree kernel method of semantic relation detection and classification (RDC) between named entities. It resolves two critical problems in previous tree kernel methods of RDC. First, a new tree ke... This paper proposes a tree kernel method of semantic relation detection and classification (RDC) between named entities. It resolves two critical problems in previous tree kernel methods of RDC. First, a new tree kernel is presented to better capture the inherent structural information in a parse tree by enabling the standard convolution tree kernel with context-sensitiveness and approximate matching of sub-trees. Second, an enriched parse tree structure is proposed to well derive necessary structural information, e.g., proper latent annotations, from a parse tree. Evaluation on the ACE RDC corpora shows that both the new tree kernel and the enriched parse tree structure contribute significantly to RDC and our tree kernel method much outperforms the state-of-the-art ones. 展开更多
关键词 semantic relation detection and classification convolution tree kernel approximate matching context sensitiveness enriched parse tree structure
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Semantic Role Labeling of Chinese Nominal Predicates with Dependency-Driven Constituent Parse Tree Structure 被引量:2
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作者 王红玲 周国栋 《Journal of Computer Science & Technology》 SCIE EI CSCD 2013年第6期1117-1126,共10页
This paper explores a tree kernel based method for semantic role labeling (SRL) of Chinese nominal predicates via a convolution tree kernel. In particular, a new parse tree representation structure, called dependenc... This paper explores a tree kernel based method for semantic role labeling (SRL) of Chinese nominal predicates via a convolution tree kernel. In particular, a new parse tree representation structure, called dependency-driven constituent parse tree (D-CPT), is proposed to combine the advantages of both constituent and dependence parse trees. This is achieved by directly representing various kinds of dependency relations in a CPT-style structure, which employs dependency relation types instead of phrase labels in CPT (Constituent Parse Tree). In this way, D-CPT not only keeps the dependency relationship information in the dependency parse tree (DPT) structure but also retains the basic hierarchical structure of CPT style. Moreover, several schemes are designed to extract various kinds of necessary information, such as the shortest path between the nominal predicate and the argument candidate, the support verb of the nominal predicate and the head argument modified by the argument candidate, from D-CPT. This largely reduces the noisy information inherent in D-CPT. Finally, a convolution tree kernel is employed to compute the similarity between two parse trees. Besides, we also implement a feature-based method based on D-CPT. Evaluation on Chinese NomBank corpus shows that our tree kernel based method on D-CPT performs significantly better than other tree kernel-based ones and achieves comparable performance with the state-of-the-art feature-based ones. This indicates the effectiveness of the novel D-CPT structure in representing various kinds of dependency relations in a CPT-style structure and our tree kernel based method in exploring the novel D-CPT structure. This also illustrates that the kernel-based methods are competitive and they are complementary with the feature- based methods on SRL. 展开更多
关键词 semantic role labeling Chinese nominal predicate dependency-driven constituent parse tree tree kernel
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Neural Parse Combination
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作者 Lin-Er Yang Mao-Song Sun +4 位作者 Yong Cheng Jia-Cheng Zhang Zheng-Hao Liu Huan-Bo Luan Yang Liu 《Journal of Computer Science & Technology》 SCIE EI CSCD 2017年第4期749-757,共9页
Analyzing the syntactic structure of natural languages by parsing is an important task in artificial intelligence. Due to the complexity of natural languages, individual parsers tend to make different yet complementar... Analyzing the syntactic structure of natural languages by parsing is an important task in artificial intelligence. Due to the complexity of natural languages, individual parsers tend to make different yet complementary errors. We propose a neural network based approach to combine parses from different parsers to yield a more accurate parse than individual ones. Unlike conventional approaches, our method directly transforms linearized candidate parses into the ground-truth parse. Experiments on the Penn English Treebank show that the proposed method improves over a state-of-the-art parser combination approach significantly. 展开更多
关键词 neural network PARSING parse combination
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ML-Parser:An Eficient and Accurate Online Log Parser 被引量:1
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作者 Yu-Qian Zhu Jia-Ying Deng +3 位作者 Jia-Chen Pu Peng Wang Shen Liang Wei Wang 《Journal of Computer Science & Technology》 SCIE EI CSCD 2022年第6期1412-1426,共15页
A log is a text message that is generated in various services,frameworks,and programs.The majority of log data mining tasks rely on log parsing as the first step,which transforms raw logs into formatted log templates.... A log is a text message that is generated in various services,frameworks,and programs.The majority of log data mining tasks rely on log parsing as the first step,which transforms raw logs into formatted log templates.Existing log parsing approaches often fail to effectively handle the trade-off between parsing quality and performance.In view of this,in this paper,we present Multi-Layer Parser(ML-Parser),an online log parser that runs in a streaming manner.Specifically,we present a multi-layer structure in log parsing to strike a balance between efficiency and effectiveness.Coarse-grained tokenization and a fast similarity measure are applied for efficiency while fine-grained tokenization and an accurate similarity measure are used for effectiveness.In experiments,we compare ML-Parser with two existing online log parsing approaches,Drain and Spell,on ten real-world datasets,five labeled and five unlabeled.On the five labeled datasets,we use the proportion of correctly parsed logs to measure the accuracy,and ML-Parser achieves the highest accuracy on four datasets.On the whole ten datasets,we use Loss metric to measure the parsing quality.ML-Parse achieves the highest quality on seven out of the ten datasets while maintaining relatively high efficiency. 展开更多
关键词 log parsing online approach structure extraction similarity measure
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PostgreSQL分析器的研究 被引量:4
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作者 郭龙江 李金宝 《黑龙江大学自然科学学报》 CAS 2001年第4期49-52,共4页
介绍了对象关系数据库系统 PostgreSQL的内部结构、查询处理的过程及 PostgreSQL语法/词法分析器的实现,并通过一个 SQL语句实例,分析了 PostgreSQL语法/词法分析器的内部结构,最后给出Quer... 介绍了对象关系数据库系统 PostgreSQL的内部结构、查询处理的过程及 PostgreSQL语法/词法分析器的实现,并通过一个 SQL语句实例,分析了 PostgreSQL语法/词法分析器的内部结构,最后给出Query树的详细数据结构图示. 展开更多
关键词 POSTGRESQL 分析器 parse Query树 对象关系数据库管理系统 系统结构 查询处理
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Risk prediction model for cataract after vitrectomy surgery:a 2-year study on primary rhegmatogenous retinal detachment
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作者 Di Gong Da-Hui Ma +3 位作者 Qing Zhang Kuan-Rong Dang Wei-Hua Yang Jian-Tao Wang 《International Journal of Ophthalmology(English edition)》 2025年第11期2106-2115,共10页
AIM:To establish a risk prediction model for secondary cataract within 2y after pars plana vitrectomy(PPV)in patients with primary rhegmatogenous retinal detachment(RRD).METHODS:Clinical data of patients with primary ... AIM:To establish a risk prediction model for secondary cataract within 2y after pars plana vitrectomy(PPV)in patients with primary rhegmatogenous retinal detachment(RRD).METHODS:Clinical data of patients with primary RRD treated at the Shenzhen Eye Hospital were retrospectively collected.Twenty-four potential influencing factors,including patient characteristics and surgical factors,were selected for analysis.Independent risk factors for secondary cataract were identified through univariate comparisons and multivariate logistic regression analysis.A risk prediction model was constructed and evaluated using receiver operating characteristic(ROC)curves,area under the ROC curve(AUC),calibration plots,and decision curve analysis(DCA)curves.RESULTS:The 386 cases(389 eyes)of patients who underwent PPV and had complete surgical records were ultimately included.Within a 2-year longitudinal observation,41.39%of patients developed cataract secondary to PPV.Logistic regression results identified a history of hypertension[odds ratio(OR)=1.78,95%CI:1.002–3.163,P=0.049],silicone oil tamponade(OR=3.667,95%CI:2.373–5.667,P=0.000),and lens thickness(OR=1.978,95%CI:1.129–3.464,P=0.017)as independent risk factors for cataract secondary to PPV.The constructed nomogram achieved AUC=0.6974.Calibration plots indicated good agreement between predicted and observed outcomes,while DCA curves demonstrated the model’s clinical utility.CONCLUSION:By incorporating a history of hypertension,vitreous substitute type,and lens thickness,this study constructs a prediction model with moderate discriminative ability.This model offers a valuable tool for clinicians to identify high-risk patients early,potentially allowing for more timely interventions and improved patient outcomes. 展开更多
关键词 rhegmatogenous retinal detachment pars plana vitrectomy CATARACT prediction model longitudinal study
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Safety and immunogenicity of RAZI Cov Pars(RCP)vaccine in children and adolescents aged 5-17 years:An open-label,single arm trial
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作者 Mohammad Hossein Fallah Mehrabadi Mojtaba Noofeli +19 位作者 Saeed Kalantari Masoud Solaymani Dodaran Mohammad Hasan Rabiee Ali Eshaghi Ali Rezaei Mokarram Seyed Hossein Razaz Monireh Hajimoradi Fariba Sadeghi Fazel Ladan Mokhberalsafa Maryam Taghdiri Mohsen Bagheri Rezvan Golmoradizadeh Elahe Bahari Roya Mostafaie Maryam Raghami Derakhshani Elaheh Ghalehnovi Safdar Masoumi NiloufarGharavi Vahideh Mohseni Seyed Reza Banihashemi 《Asian Pacific Journal of Tropical Medicine》 2025年第7期302-312,共11页
Objective:To investigate the safety and immunogenicity of the RAZI Cov Pars(RCP)vaccine in children and adolescents aged 5-17 years.Methods:In this open-label,single arm trial,26 of the 68 registered volunteers met th... Objective:To investigate the safety and immunogenicity of the RAZI Cov Pars(RCP)vaccine in children and adolescents aged 5-17 years.Methods:In this open-label,single arm trial,26 of the 68 registered volunteers met the inclusion criteria.The participants reccived RCP vaccinc twice intramuscularly(on days 0 and 21)and intranasally on day 51.Safety was assessed up to 6 months after the second dose.Immunogenicity was assessed on days 35,90,and 180 by measuring ncutralizing antibody levels as well as anti-RBD and anti-S,IgG antibodies.Results:Among the 26 volunteers,22 were in the age group of 5-11 years,and 4 were in the agc group of 12-17 years.No grade 3 or higher local or systemic adverse reactions were reported one weck after vaccination.Sixabnormal laboratory findings were observed after both vaccine doses,none of which were classified as grade 3 or higher.During a total follow-up period of 3875 person-years,31 adverse events were recorded(incidence rate:0.008).The scroconversion rates for VNT,anti-RBD and anti-S:IgGantibodies two wecks after recciving the second dose were 72.7%,76.2%and 80.9%,respectively.In the 5-11 year agc group,the scroconversion rates for VNT,anti-RBDand anti-S_(1) were 78.9%,83.3%and 88.9%,respectively.Conclusions:Intramuscular and intranasal administration of the RCPvaccine did not lead to scrious adverse events in any of the children or adolescents.The vaccine clicited a robust response in the 5-11 year age group two wecks after the second dose.Considering that this group reccived half of the adult vaccine dose,these results support the suitability of this dose for the study group. 展开更多
关键词 RAZI Cov Pars vaccine TRIAL Children Adolescent
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Chinese relation extraction for constructing satellite frequency and orbit knowledge graph:A survey
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作者 Yuanzhi He Zhiqiang Li Zheng Dou 《Digital Communications and Networks》 2025年第5期1305-1317,共13页
As Satellite Frequency and Orbit(SFO)constitute scarce natural resources,constructing a Satellite Frequency and Orbit Knowledge Graph(SFO-KG)becomes crucial for optimizing their utilization.In the process of building ... As Satellite Frequency and Orbit(SFO)constitute scarce natural resources,constructing a Satellite Frequency and Orbit Knowledge Graph(SFO-KG)becomes crucial for optimizing their utilization.In the process of building the SFO-KG from Chinese unstructured data,extracting Chinese entity relations is the fundamental step.Although Relation Extraction(RE)methods in the English field have been extensively studied and developed earlier than their Chinese counterparts,their direct application to Chinese texts faces significant challenges due to linguistic distinctions such as unique grammar,pictographic characters,and prevalent polysemy.The absence of comprehensive reviews on Chinese RE research progress necessitates a systematic investigation.A thorough review of Chinese RE has been conducted from four methodological approaches:pipeline RE,joint entityrelation extraction,open domain RE,and multimodal RE techniques.In addition,we further analyze the essential research infrastructure,including specialized datasets,evaluation benchmarks,and competitions within Chinese RE research.Finally,the current research challenges and development trends in the field of Chinese RE were summarized and analyzed from the perspectives of ecological construction methods for datasets,open domain RE,N-ary RE,and RE based on large language models.This comprehensive review aims to facilitate SFO-KG construction and its practical applications in SFO resource management. 展开更多
关键词 Relation extraction Information extraction Distant supervision Parsing tree Joint entity-relation extraction
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Macular epiretinal membrane in high myopia:timing and prognosis of pars plana vitrectomy surgery
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作者 Yu-Tong Xia Jia-Yun Ge +5 位作者 Zong-Chan Zhang Li-Yue Zhang Ying-Ying Wen Ying Xie Ye Shen Jian-Ping Tong 《International Journal of Ophthalmology(English edition)》 2025年第9期1689-1696,共8页
AIM:To investigate the outcomes and prognosis of macular epiretinal membrane(ERM)after pars plana vitrectomy(PPV)in patients with high myopia(HM),focusing on the optimal timing of surgery and its impact on prognosis.M... AIM:To investigate the outcomes and prognosis of macular epiretinal membrane(ERM)after pars plana vitrectomy(PPV)in patients with high myopia(HM),focusing on the optimal timing of surgery and its impact on prognosis.METHODS:The clinical data of 50 eyes from 49 patients diagnosed with ERM,who were highly myopic and underwent PPV were retrospectively analyzed.The patients with ERM were classified into five groups based on the characteristics associated with different levels of myopic traction maculopathy.Group 1:Simple ERM without complex vertical and tangential direction traction on retina on optical coherence tomography(OCT)image;Group 2:ERM with obvious macular foveal schisis,without macular hole(MH);Group 3:ERM with inner lamellar MH,with or without macular foveal schisis;Group 4:ERM with outer lamellar MH,with or without foveal retinal detachment(RD);Group 5:ERM with full-thickness MH.Baseline characteristics,changes in best corrected visual acuity(BCVA)before and after surgery,and anatomical characteristics through spectral domain OCT were compared.RESULTS:The 50 eyes were followed for 6mo,with an average age of 58.66y and an average axial length(AL)of 28.69 mm.Among the five groups,postoperative logMAR BCVA improved(P<0.05).Group 1 had better mean BCVA at baseline(0.59±0.36)and at 6mo postoperatively(0.16±0.22)compared to the other groups,while Group 5 had worse mean BCVA at baseline(1.68±0.45)and at 6mo postoperatively(1.27±0.64).There were no statistically significant differences in sex,age or AL between the groups(P>0.05).OCT showed that Groups 4 and 5 exhibited poorer macular anatomy compared to the other three groups,as evidenced by lower rates of central retinal reattachment(64.3%in Group 4,86.7%in Group 5)and integrity of the inner segment/outer segment of photoreceptor junction(28.6%in Group 4,26.7%in Group 5).CONCLUSION:PPV is an effective treatment for ERM in patients with HM.All groups showed postoperative improvement in BCVA compared to preoperative levels,demonstrating the necessity of surgical intervention.Early intervention,particularly before the fourth stage of the disease,may lead to better visual outcomes. 展开更多
关键词 epiretinal membrane myopic traction maculopathy pars plana vitrectomy high myopia visual acuity
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Ten surgical pearls adapted from ancient Chinese allusions in managing severe proliferative diabetic retinopathy
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作者 Chen Zhe Wu Chan +3 位作者 Zhou Yan Lin Shiqun Xiao Xingyu Dai Rongping 《国际眼科杂志》 2025年第5期698-705,共8页
AIM:To summarize 10 surgical pearls for managing proliferative diabetic retinopathy(PDR)adapted from the ancient Chinese allusions and analyze the application of these pearls in a real-world fashion.METHODS:Retrospect... AIM:To summarize 10 surgical pearls for managing proliferative diabetic retinopathy(PDR)adapted from the ancient Chinese allusions and analyze the application of these pearls in a real-world fashion.METHODS:Retrospective,noncomparative,interventional study.Ten surgical pearls were summarized and adapted from the ancient Chinese philosophy.Totally 346 cases(443 eyes)that underwent pars plana vitrectomy(PPV)at our hospial from January 2016 to February 2024 were selected.Flexible combinations of these pearls were applied according to the specific condition of each patient during surgeries.The efficacy and safety were analyzed,as well as the application frequencies according to the existence of tractional retinal detachment or not.RESULTS:A total of 473 times of surgeries were performed on all the patients.According to ancient Chinese allusions,ten surgical pearls were summarized from these surgeries.All PPVs went smoothly with the application of different combinations.Finally,almost all proliferative membranes were successfully peeled except for 10 patients(11 eyes),who went through strategy No.10(minimal membranectomy)that,only necessary relaxation incisions were made with most of the proliferative membranes left on purpose.The final visual acuities were mostly improved or stable(1.92±0.83 LogMAR preoperatively vs 1.16±0.85 LogMAR postoperatively,P<0.01).Postoperative complications mainly included early inflammatory responses in the anterior chamber and nuclear sclerosis.Recurrent vitreous hemorrhage,retinal detachment,and hyphema or neovascular glaucoma occurred in 1.9%(9/473),3.2%(15/473),0.4%(2/473)and 0.4%(2/473)times of PPVs,respectively.After 12/473(2.5%)times of PPVs,retinal detachment at the macular area still existed,and multiple times of subsequent PPVs were conducted.Final retinal attachment at the macular area was realized in 98.9%eyes.Those 5 unattached eyes were with heavily reproliferated membranes and subsequent tractional retinal detachment recurrence under the oil,and three of them were scleral buckled additionally.CONCLUSION:These 10 surgical strategies and technique pearls were mostly effective and safe in the management of severe PDR patients.They were relatively easy to be memorized and applicated once the meaning of each Chinese idiom was understood.One can use different combinations flexibly according to a patient’s specific condition. 展开更多
关键词 surgical pearls ancient Chinese allusions Chinese idioms proliferative diabetic retinopathy pars plana vitrectomy
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KD-SegNet: Efficient Semantic Segmentation Network with Knowledge Distillation Based on Monocular Camera
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作者 Thai-Viet Dang Nhu-Nghia Bui Phan Xuan Tan 《Computers, Materials & Continua》 2025年第2期2001-2026,共26页
Due to the necessity for lightweight and efficient network models, deploying semantic segmentation models on mobile robots (MRs) is a formidable task. The fundamental limitation of the problem lies in the training per... Due to the necessity for lightweight and efficient network models, deploying semantic segmentation models on mobile robots (MRs) is a formidable task. The fundamental limitation of the problem lies in the training performance, the ability to effectively exploit the dataset, and the ability to adapt to complex environments when deploying the model. By utilizing the knowledge distillation techniques, the article strives to overcome the above challenges with the inheritance of the advantages of both the teacher model and the student model. More precisely, the ResNet152-PSP-Net model’s characteristics are utilized to train the ResNet18-PSP-Net model. Pyramid pooling blocks are utilized to decode multi-scale feature maps, creating a complete semantic map inference. The student model not only preserves the strong segmentation performance from the teacher model but also improves the inference speed of the prediction results. The proposed method exhibits a clear advantage over conventional convolutional neural network (CNN) models, as evident from the conducted experiments. Furthermore, the proposed model also shows remarkable improvement in processing speed when compared with light-weight models such as MobileNetV2 and EfficientNet based on latency and throughput parameters. The proposed KD-SegNet model obtains an accuracy of 96.3% and a mIoU (mean Intersection over Union) of 77%, outperforming the performance of existing models by more than 15% on the same training dataset. The suggested method has an average training time that is only 0.51 times less than same field models, while still achieving comparable segmentation performance. Hence, the semantic segmentation frames are collected, forming the motion trajectory for the system in the environment. Overall, this architecture shows great promise for the development of knowledge-based systems for MR’s navigation. 展开更多
关键词 Mobile robot navigation semantic segmentation knowledge distillation pyramid scene parsing fully convolutional networks
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Rapid-onset neovascular glaucoma following cataract surgery in diabetes:outcomes of pars plana vitrectomy combined with Ahmed glaucoma valve implantation
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作者 Hui-Ping Yao Ya-Nuo Wang +3 位作者 Yan-Wei Chen Sha Gao Yi-Sheng Zhong Xi Shen 《International Journal of Ophthalmology(English edition)》 2025年第9期1665-1672,共8页
AIM:To present a case series of rapid-onset neovascular glaucoma(NVG)accompanied by vitreous haemorrhage(VH)following cataract surgery in diabetic patients,and to evaluate the efficacy of pars plana vitrectomy(PPV)com... AIM:To present a case series of rapid-onset neovascular glaucoma(NVG)accompanied by vitreous haemorrhage(VH)following cataract surgery in diabetic patients,and to evaluate the efficacy of pars plana vitrectomy(PPV)combined with Ahmed glaucoma valve(AGV)implantation.METHODS:This is a retrospective,single-center,consecutive case series.All patients underwent 23-gauge PPV with AGV implantation 2–3d after intravitreal ranibizumab injection(IVR).The minimum postoperative follow-up period lasted 12mo.The primary outcome measures included bestcorrected visual acuity(BCVA),intraocular pressure(IOP),and topical hypotensive medications.RESULTS:Fifteen diabetic patients(age,46–81y)with rapid-onset NVG and VH following uncomplicated phacoemulsification were included.The median time to the initial NVG diagnosis following cataract surgery was within 4wk.After PPV combined with AGV implantation,the mean BCVA(logMAR)improved from 1.9(range:1.0 to 2.6)preoperatively to 1.2(range:0.2 to 2.6)at the final follow-up.Baseline BCVA and the presence of diabetic nephropathy(DN)were significantly associated with the final BCVA in the multiple regression model.The mean postoperative IOP at all follow-up visits was significantly reduced compared to baseline.At the final follow-up,9 patients required one or two topical ocular hypotensive medications,while the other 6 needed not.Success was achieved in 87%,and the reoperation rate was 20%.The majority of NVG cases(9/15)were primarily attributed to the rapid progression of proliferative diabetic retinopathy.However,a notable subset(6 eyes)was complicated retinal vein occlusion or carotid artery occlusion.CONCLUSION:PPV combined with AGV implantation after adjuvant IVR for rapid-onset NVG with VH following diabetic cataract surgery is one of the safe and effective treatments.Baseline BCVA and preexisting DN may be potential indicators for visual outcomes. 展开更多
关键词 diabetic retinopathy neovascular glaucoma pars plana vitrectomy Ahmed glaucoma valve implantation
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Vitrectomy combined with internal limiting membrane peeling for refractory macular telangiectasia type 1
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作者 Dan Liao Xiao-Li Yang Rong Li 《International Journal of Ophthalmology(English edition)》 2025年第6期1169-1172,共4页
Dear Editor,I diopathic macular telangiectasia(MacTel)type 1 is a retinal vascular disease characterized by abnormal dilation of macular capillaries,leading to metamorphopsia,progressive vision loss,and temporal scoto... Dear Editor,I diopathic macular telangiectasia(MacTel)type 1 is a retinal vascular disease characterized by abnormal dilation of macular capillaries,leading to metamorphopsia,progressive vision loss,and temporal scotoma enlargement.Currently,there is no standardized treatment protocol for MacTel type 1[1-2].Treatment outcomes can vary significantly among individuals,highlighting the ongoing need for further exploration of new and more effective treatment options.This paper presents a case of refractory macular edema associated with MacTel type 1,which showed a favorable response to pars plana vitrectomy(PPV)and internal limiting membrane(ILM)peeling. 展开更多
关键词 vitreoretinal surgery treatment protocol pars plana vitrectomy retinal vascular disease refractory macular edema abnormal dilation macular capillariesleading macular telangiectasia mactel type refractory macula
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PARS评分法在麻醉恢复室的应用 被引量:9
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作者 吕凯 陈肖敏 祁海鸥 《护士进修杂志》 北大核心 2008年第10期882-883,共2页
目的探讨PARS评分法在麻醉恢复室(PACU)中的应用价值。方法将收入PACU的2 562例全麻术后患者分成老年组、中年组和青年组三组,运用PARS评分法分别对患者进行出室和入室评分,同时观察、记录患者在PACU期间的相关生命指征和留室时间。结... 目的探讨PARS评分法在麻醉恢复室(PACU)中的应用价值。方法将收入PACU的2 562例全麻术后患者分成老年组、中年组和青年组三组,运用PARS评分法分别对患者进行出室和入室评分,同时观察、记录患者在PACU期间的相关生命指征和留室时间。结果老、中、青三组入室时的评分分别为2.1±1.5、3.2±1.6和4.1±1.4,出室时的评分则分别提高至7.3±1.3、8.4±0.8和8.6±0.5,差异有显著意义(t1=6.28,t2=6.16,t3=5.75,P<0.01)。老年组留室时间最长。指标的相关性分析显示,出室评分与入室评分呈显著正相关(r=0.446,P<0.01),与留室时间呈负相关(r=-0.392,P<0.05)。ASA评级分别与入室、出室评分呈显著负相关(r=-0.362,P<0.01和r=-0.413,P<0.01),与留室时间呈正相关(r=0.370,P<0.05)。结论PARS评分法可以定量地判断患者的恢复情况,提高PACU护理工作的预见性,对于指导治疗、保障全麻术后病人的安全具有十分重要的意义,是一种科学、有效的评估方法。 展开更多
关键词 PARS评分法 麻醉恢复室 护理管理
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利用RNAi抑制PARs防治脑缺血性损伤的实验研究 被引量:2
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作者 王莹 祝萍 +4 位作者 王昆祥 姜海智 王旭东 姜宏佺 郑永慧 《现代生物医学进展》 CAS 2011年第22期4256-4259,共4页
目的:利用RNA干扰技术,通过重组腺病毒导入,抑制脑组织中PARs基因的表达,观察神经功能缺陷评分、缺血脑组织梗死体积的变化,为缺血性脑血管疾病的基因治疗提供实验依据。方法:雄性Wistar大鼠随机分组,以重组腺病毒介导的无序PARs基因sh... 目的:利用RNA干扰技术,通过重组腺病毒导入,抑制脑组织中PARs基因的表达,观察神经功能缺陷评分、缺血脑组织梗死体积的变化,为缺血性脑血管疾病的基因治疗提供实验依据。方法:雄性Wistar大鼠随机分组,以重组腺病毒介导的无序PARs基因shRNA片段、生理盐水进行干预,干预3天后以线栓法建立Wistar大鼠大脑中动脉永久闭塞模型,各组分别于线栓后24h、72h进行神经功能缺陷评分并断头取脑,应用4%TTC染色测脑梗死体积。结果:1.缺血后24h、72h同一时间点:①实验组分别与对照组、生理盐水组对比,神经功能缺陷评分明显降低(P<0.05),脑梗死体积明显减小(P<0.05);②对照组与生理盐水组对比,神经功能缺陷评分、脑梗死体积无明显差异(P>0.05)。2.各组组内缺血后24h、72h对比,神经功能缺陷评分、脑梗死体积各组均有明显差异(P<0.05)。结论:重组腺病毒介导的RNAi能有效抑制脑组织中PARs基因的表达,缩小脑梗死体积,改善神经功能缺陷评分。 展开更多
关键词 RNAI PARS 重组腺病毒 脑缺血
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IL-29对胰蛋白酶诱导的肥大细胞PARs表达的调节作用 被引量:5
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作者 隋丽 陈冬 +1 位作者 张慧云 何韶衡 《中国免疫学杂志》 CAS CSCD 北大核心 2014年第5期609-612,622,共5页
目的:检测白细胞介素29(Interleukin-29,IL-29)对胰蛋白酶引起的肥大细胞蛋白酶激活受体(Protease activated receptor,PAR)-1,2,3,4表达的调节作用。方法:P815肥大细胞培养后,用不同浓度的IL-29、胰蛋白酶单独或联合激发肥大细胞,在不... 目的:检测白细胞介素29(Interleukin-29,IL-29)对胰蛋白酶引起的肥大细胞蛋白酶激活受体(Protease activated receptor,PAR)-1,2,3,4表达的调节作用。方法:P815肥大细胞培养后,用不同浓度的IL-29、胰蛋白酶单独或联合激发肥大细胞,在不同时间点收集激发细胞,用流式细胞术(FCM)及实时定量PCR检测P815肥大细胞蛋白酶激活受体的表达。结果:IL-29单独作用能够下调肥大细胞PAR-1蛋白及mRNA水平的表达,上调PAR-3、PAR-4 mRNA的表达,与对照组相比差异有统计学意义(P<0.05);以IL-29预处理肥大细胞后,IL-29对胰蛋白酶诱导的肥大细胞PAR-2、PAR-3、PAR-4表达起促进作用,与对照组相比差异具有统计学意义(P<0.05)。结论:IL-29能够调节胰蛋白酶引起的肥大细胞PARs表达,从而参与肥大细胞相关的炎症反应。 展开更多
关键词 肥大细胞 白细胞介素29(IL-29) 胰蛋白酶 蛋白酶激活受体(PARs) 流式细胞术
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百万千瓦级压水堆严重事故下氢气源项及氢气控制有效性分析 被引量:4
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作者 邹杰 佟立丽 +6 位作者 曹学武 顾健 薛峻峰 江宇 郝禄禄 仇苏辰 刘力 《核动力工程》 EI CAS CSCD 北大核心 2013年第S1期47-50,共4页
针对百万千瓦级压水堆核电厂大型干式安全壳在严重事故情况下的氢气风险控制,建立了一体化事故分析模型,分别对大破口失水事故(LB-LOCA)、中破口失水事故(MB-LOCA)、小破口失水事故(SB-LOCA)、全厂断电事故(SBO)、蒸汽发生器(SG)传热管... 针对百万千瓦级压水堆核电厂大型干式安全壳在严重事故情况下的氢气风险控制,建立了一体化事故分析模型,分别对大破口失水事故(LB-LOCA)、中破口失水事故(MB-LOCA)、小破口失水事故(SB-LOCA)、全厂断电事故(SBO)、蒸汽发生器(SG)传热管破裂事故(SGTR)以及主蒸汽管道破裂事故(MSLB)进行事故进程计算以及氢气源项分析。相对于其他事故序列,LB-LOCA下堆芯快速熔化,锆-水反应产生氢气的速率快,可以作为安全壳内氢气风险控制有效性分析的代表性事故序列。分析表明,严重事故情况下在安全壳中安装一定数量的非能动氢气复合器(PARs)能够有效去除安全壳中的氢气,消除氢气燃烧或爆炸的风险,保持安全壳的完整性。 展开更多
关键词 严重事故 氢气风险 大型干式安全壳 氢气复合器(PARs)
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