Objective To draw on the experience of the construction and development of drug traceability system in the USA and to provide reference for improving China’s drug traceability system.Methods Literature research and c...Objective To draw on the experience of the construction and development of drug traceability system in the USA and to provide reference for improving China’s drug traceability system.Methods Literature research and comparative study were used to sort out the background and development of drug traceability system in the USA,including drug traceability code,drug traceability model,drug traceability platform and the application of blockchain technology.On this basis,some suggestions on the construction of drug traceability system in China were put forward.Results and Conclusion The United States has a perfect system of laws and regulations on drug traceability,which encourages the construction of third-party traceability platforms to avoid the formation of monopolies.Besides,the application of blockchain technology in the construction of drug traceability system is also relatively mature.It is suggested that China strengthen the construction of drug traceability system,give play to the advantages of third-party traceability platforms,and improve the application of blockchain technology in drug traceability.展开更多
Carbonaceous aerosol,including organic carbon(OC)and elemental carbon(EC),has significant influence on human health,air quality and climate change.Accurate measurement of carbonaceous aerosol is essential to reduce th...Carbonaceous aerosol,including organic carbon(OC)and elemental carbon(EC),has significant influence on human health,air quality and climate change.Accurate measurement of carbonaceous aerosol is essential to reduce the uncertainty of radiative forcing estimation and source apportionment.The accurate separation of OC and EC is controversial due to the charring of OC.Therefore,the development of reference materials(RM)for the validation of OC/EC separation is an important basis for further study.Previous RMs were mainly based on ambient air sampling,which could not provide traceability of OC and EC concentration.To develop traceable RMs with known OC/EC contents,our study applied an improved aerosol generation and mixing technique,providing uniform deposition of particles on quartz filters.To generate OC aerosol with similar pyrolytic property of ambient aerosol,both water soluble organic carbon(WSOC)and water insoluble organic carbon(WIOC)were used,and amorphous carbon was selected for EC surrogate.The RMs were analyzed using different protocols.The homogeneity within the filter was validated,reaching below 2%.The long-term stability of RMs has been validated with RSD ranged from 1.7%–3.2%.Good correlationwas observed between nominal concentration of RMswithmeasured concentration by two protocols,while the difference of EC concentration was within 20%.The results indicated that the newly developed RMs were acceptable for the calibration of OC and EC,which could improve the accuracy of carbonaceous aerosol measurement.Moreover,the laboratory-generated EC-RMs could be suitable for the calibration of equivalent BC concentration by Aethalometers.展开更多
Almond is widely cultivated in the world thanks to the quality and healthy features of the kernel.Almond kernel is consumed fresh or employed in the food industry.Hundreds of almond cultivars were selected throughout ...Almond is widely cultivated in the world thanks to the quality and healthy features of the kernel.Almond kernel is consumed fresh or employed in the food industry.Hundreds of almond cultivars were selected throughout the long history of cultivation;in this context,an efficient method for varietal identification is essential to ensure cultivar traceability along the chain.This study surveyed the widely employed commercial kits and protocols for DNA extraction from several almond matrices including leaves,kernels(fresh and roasted)and several processed products.Commercial kits(though with minor modification)outperformed the other extraction methods for the isolation of DNA suitable for molecular analysis from all the tested matrices.In parallel,a germplasm collection composed of 140 accessions(123 Sicilian genotypes complemented with widely known national and international cultivars)was genotyped with the Axiom^(TM)60K almond SNP Array enabling the detection of 6374 unique SNPs that can be readily used for varietal traceability.A subset of unique SNPs was further validated employing a high-resolution melting(HRM)assay on a discovery panel encompassing ten of the most widely cultivated accessions.The DNA extracted from leaves and kernels of five cultivars was genotyped with eight SSRs allowing the identification of the maternal origin of each kernel.The paper integrates the survey of the widely employed protocols for DNA extraction with the high-throughput genotyping of 140 almond accessions.In this context,unique SNPs validated and optimized for an HRM assay and the availability of SSR markers demonstrated their efficacy in traceability analysis along the chain.展开更多
With the popularity of the Internet of Vehicles(IoV),a large amount of data is being generated every day.How to securely share data between the IoV operator and various value-added service providers becomes one of the...With the popularity of the Internet of Vehicles(IoV),a large amount of data is being generated every day.How to securely share data between the IoV operator and various value-added service providers becomes one of the critical issues.Due to its flexible and efficient fine-grained access control feature,Ciphertext-Policy Attribute-Based Encryption(CP-ABE)is suitable for data sharing in IoV.However,there are many flaws in most existing CP-ABE schemes,such as attribute privacy leakage and key misuse.This paper proposes a Traceable and Revocable CP-ABE-based Data Sharing with Partially hidden policy for IoV(TRE-DSP).A partially hidden access structure is adopted to hide sensitive user attribute values,and attribute categories are sent along with the ciphertext to effectively avoid privacy exposure.In addition,key tracking and malicious user revocation are introduced with broadcast encryption to prevent key misuse.Since the main computation task is outsourced to the cloud,the burden of the user side is relatively low.Analysis of security and performance demonstrates that TRE-DSP is more secure and practical for data sharing in IoV.展开更多
As the cornerstone of sterile instrument maintenance in endoscopy centers,the quality of endoscope cleaning directly impacts hospital infection control effectiveness.The traceability system for endoscopy centers utili...As the cornerstone of sterile instrument maintenance in endoscopy centers,the quality of endoscope cleaning directly impacts hospital infection control effectiveness.The traceability system for endoscopy centers utilizes digital means to document the entire cleaning process,enabling real-time monitoring and precise quality control.This paper analyzes current quality control practices in endoscope cleaning and addresses existing challenges.It explores how traceability systems standardize procedures,enhance monitoring,and improve management efficiency.The study proposes optimization strategies for traceability system implementation,clarifying its core value in endoscope cleaning quality control.These findings provide theoretical foundations and practical guidance for hospitals to refine management of endoscopy centers,ensure diagnostic safety,and reduce infection risks,ultimately advancing endoscope cleaning quality control toward standardized and informatized development.展开更多
[Objective] To establish the traceability mechanism of agricultural products safety, and the application of promote domestic based software in the supervision area of agricultural products quality and safety. [Method]...[Objective] To establish the traceability mechanism of agricultural products safety, and the application of promote domestic based software in the supervision area of agricultural products quality and safety. [Method] Through the analysis on the circulation characteristics of agricultural products, like fruits, vegetables, livestock and poultry, the agricultural products quality safety management and traceability query business component libraries were designed. Based on the run-time-supporting environment provided by domestic based software, traceability management system of agricultural products quality and safety was constructed. [Result] The traceability management system provided the information interaction and comprehensive management platform of agricultural product quality and safety based on domestic based software for the government, enterprises and consumers. [Conclusion] Through the application demonstration, the quality control and information traceability of full circulation of agricultural products was achieved effective and reliably, and the management level of agricultural products quality and safety was improved.展开更多
It is the key to construct the traceability mechanism of quality responsibility for ensuring the quality and safety of animal products. In this study, after defining the concept of traceability system and analyzing it...It is the key to construct the traceability mechanism of quality responsibility for ensuring the quality and safety of animal products. In this study, after defining the concept of traceability system and analyzing its function mechanism, the design ideas of pork quality and safety traceability system based on bar code and Internet were put forward, including network structure, system process, business process and information identifica- tion. Then the relevant management systems were proposed.展开更多
[Objective] In response to pig breeding stage characteristics,the research aimed to design the traceability system to realize the pig product marking which based on RFID technology. [Method] The antenna＇s design meth...[Objective] In response to pig breeding stage characteristics,the research aimed to design the traceability system to realize the pig product marking which based on RFID technology. [Method] The antenna＇s design method of electronic tag and reader antenna were expounded and different antennas were used for testing communication test of RFID system. [Result] When the parameter setup such as data transportation ratio was same,the communication distance of external antenna was farther than RCB antenna; compare with three external antennas,the communication distance of coaxial antenna and wall-hanged antenna were farther. In 500 kbps transfer rate,communication distance was within 28 meters,and in 250 kbps transfer rate,communication distance was within 40 meters. Considered the cost of hardware,the price of wall-hanged antenna was higher than coaxial antenna,so in the same communication distance request,system selected coaxial antenna. [Conclusion] During the pig breeding stage,by dint of electronic tag and reader designed by the research could improve the safety of the pork and fully realize the track of source of food and provide technology support for the transparent management of food safety.展开更多
文摘Objective To draw on the experience of the construction and development of drug traceability system in the USA and to provide reference for improving China’s drug traceability system.Methods Literature research and comparative study were used to sort out the background and development of drug traceability system in the USA,including drug traceability code,drug traceability model,drug traceability platform and the application of blockchain technology.On this basis,some suggestions on the construction of drug traceability system in China were put forward.Results and Conclusion The United States has a perfect system of laws and regulations on drug traceability,which encourages the construction of third-party traceability platforms to avoid the formation of monopolies.Besides,the application of blockchain technology in the construction of drug traceability system is also relatively mature.It is suggested that China strengthen the construction of drug traceability system,give play to the advantages of third-party traceability platforms,and improve the application of blockchain technology in drug traceability.
基金supported by the National Natural Science Foundation of China(No.22206180)the funds for establishing basic quality and technology capabilities(No.ANL2203)the special fund for basic scientific research business of central public research institutes(No.AKYZD2207-4)。
文摘Carbonaceous aerosol,including organic carbon(OC)and elemental carbon(EC),has significant influence on human health,air quality and climate change.Accurate measurement of carbonaceous aerosol is essential to reduce the uncertainty of radiative forcing estimation and source apportionment.The accurate separation of OC and EC is controversial due to the charring of OC.Therefore,the development of reference materials(RM)for the validation of OC/EC separation is an important basis for further study.Previous RMs were mainly based on ambient air sampling,which could not provide traceability of OC and EC concentration.To develop traceable RMs with known OC/EC contents,our study applied an improved aerosol generation and mixing technique,providing uniform deposition of particles on quartz filters.To generate OC aerosol with similar pyrolytic property of ambient aerosol,both water soluble organic carbon(WSOC)and water insoluble organic carbon(WIOC)were used,and amorphous carbon was selected for EC surrogate.The RMs were analyzed using different protocols.The homogeneity within the filter was validated,reaching below 2%.The long-term stability of RMs has been validated with RSD ranged from 1.7%–3.2%.Good correlationwas observed between nominal concentration of RMswithmeasured concentration by two protocols,while the difference of EC concentration was within 20%.The results indicated that the newly developed RMs were acceptable for the calibration of OC and EC,which could improve the accuracy of carbonaceous aerosol measurement.Moreover,the laboratory-generated EC-RMs could be suitable for the calibration of equivalent BC concentration by Aethalometers.
基金the PRIMA project:MEDPOMESTONE(Grant No.23A01284).
文摘Almond is widely cultivated in the world thanks to the quality and healthy features of the kernel.Almond kernel is consumed fresh or employed in the food industry.Hundreds of almond cultivars were selected throughout the long history of cultivation;in this context,an efficient method for varietal identification is essential to ensure cultivar traceability along the chain.This study surveyed the widely employed commercial kits and protocols for DNA extraction from several almond matrices including leaves,kernels(fresh and roasted)and several processed products.Commercial kits(though with minor modification)outperformed the other extraction methods for the isolation of DNA suitable for molecular analysis from all the tested matrices.In parallel,a germplasm collection composed of 140 accessions(123 Sicilian genotypes complemented with widely known national and international cultivars)was genotyped with the Axiom^(TM)60K almond SNP Array enabling the detection of 6374 unique SNPs that can be readily used for varietal traceability.A subset of unique SNPs was further validated employing a high-resolution melting(HRM)assay on a discovery panel encompassing ten of the most widely cultivated accessions.The DNA extracted from leaves and kernels of five cultivars was genotyped with eight SSRs allowing the identification of the maternal origin of each kernel.The paper integrates the survey of the widely employed protocols for DNA extraction with the high-throughput genotyping of 140 almond accessions.In this context,unique SNPs validated and optimized for an HRM assay and the availability of SSR markers demonstrated their efficacy in traceability analysis along the chain.
基金supported by the National Natural Science Foundation of China(No.62272076)。
文摘With the popularity of the Internet of Vehicles(IoV),a large amount of data is being generated every day.How to securely share data between the IoV operator and various value-added service providers becomes one of the critical issues.Due to its flexible and efficient fine-grained access control feature,Ciphertext-Policy Attribute-Based Encryption(CP-ABE)is suitable for data sharing in IoV.However,there are many flaws in most existing CP-ABE schemes,such as attribute privacy leakage and key misuse.This paper proposes a Traceable and Revocable CP-ABE-based Data Sharing with Partially hidden policy for IoV(TRE-DSP).A partially hidden access structure is adopted to hide sensitive user attribute values,and attribute categories are sent along with the ciphertext to effectively avoid privacy exposure.In addition,key tracking and malicious user revocation are introduced with broadcast encryption to prevent key misuse.Since the main computation task is outsourced to the cloud,the burden of the user side is relatively low.Analysis of security and performance demonstrates that TRE-DSP is more secure and practical for data sharing in IoV.
文摘As the cornerstone of sterile instrument maintenance in endoscopy centers,the quality of endoscope cleaning directly impacts hospital infection control effectiveness.The traceability system for endoscopy centers utilizes digital means to document the entire cleaning process,enabling real-time monitoring and precise quality control.This paper analyzes current quality control practices in endoscope cleaning and addresses existing challenges.It explores how traceability systems standardize procedures,enhance monitoring,and improve management efficiency.The study proposes optimization strategies for traceability system implementation,clarifying its core value in endoscope cleaning quality control.These findings provide theoretical foundations and practical guidance for hospitals to refine management of endoscopy centers,ensure diagnostic safety,and reduce infection risks,ultimately advancing endoscope cleaning quality control toward standardized and informatized development.
基金Supported by Common Chips and Basic Software Products(2010ZX01045-001-004-3)~~
文摘[Objective] To establish the traceability mechanism of agricultural products safety, and the application of promote domestic based software in the supervision area of agricultural products quality and safety. [Method] Through the analysis on the circulation characteristics of agricultural products, like fruits, vegetables, livestock and poultry, the agricultural products quality safety management and traceability query business component libraries were designed. Based on the run-time-supporting environment provided by domestic based software, traceability management system of agricultural products quality and safety was constructed. [Result] The traceability management system provided the information interaction and comprehensive management platform of agricultural product quality and safety based on domestic based software for the government, enterprises and consumers. [Conclusion] Through the application demonstration, the quality control and information traceability of full circulation of agricultural products was achieved effective and reliably, and the management level of agricultural products quality and safety was improved.
文摘It is the key to construct the traceability mechanism of quality responsibility for ensuring the quality and safety of animal products. In this study, after defining the concept of traceability system and analyzing its function mechanism, the design ideas of pork quality and safety traceability system based on bar code and Internet were put forward, including network structure, system process, business process and information identifica- tion. Then the relevant management systems were proposed.
基金Supported by National Science and Technology Support Plan Subtopic (No. 2006BAD14B04)Yunnan Province Agriculture Science and Technology Innovation Project (2008LA020)~~
文摘[Objective] In response to pig breeding stage characteristics,the research aimed to design the traceability system to realize the pig product marking which based on RFID technology. [Method] The antenna＇s design method of electronic tag and reader antenna were expounded and different antennas were used for testing communication test of RFID system. [Result] When the parameter setup such as data transportation ratio was same,the communication distance of external antenna was farther than RCB antenna; compare with three external antennas,the communication distance of coaxial antenna and wall-hanged antenna were farther. In 500 kbps transfer rate,communication distance was within 28 meters,and in 250 kbps transfer rate,communication distance was within 40 meters. Considered the cost of hardware,the price of wall-hanged antenna was higher than coaxial antenna,so in the same communication distance request,system selected coaxial antenna. [Conclusion] During the pig breeding stage,by dint of electronic tag and reader designed by the research could improve the safety of the pork and fully realize the track of source of food and provide technology support for the transparent management of food safety.
