目的：研究核糖体蛋白S15a（ribosomal protein S15a RPS15a）基因在胃癌及癌旁组织中表达差异，为进一步了解胃癌发生、发展的分子机制提供帮助。方法应用荧光定量PCR等方法进一步验证该基因在胃癌及癌旁组织中的表达差异，并在多种肿...目的：研究核糖体蛋白S15a（ribosomal protein S15a RPS15a）基因在胃癌及癌旁组织中表达差异，为进一步了解胃癌发生、发展的分子机制提供帮助。方法应用荧光定量PCR等方法进一步验证该基因在胃癌及癌旁组织中的表达差异，并在多种肿瘤细胞中的表达量进行比较。结果该基因在胃癌组织中的表达量高于其对应的癌旁组织，但在多种肿瘤细胞中的表达量无显著差异。结论 RPS15a基因在胃癌中呈高表达，说明其可能与细胞恶性生物学行为相关。在多种肿瘤细胞中表达量无显著差异，推测其可能在恶性肿瘤中的高表达具有普遍性。展开更多
We give some theorems of strong law of large numbers and complete convergence for sequences of φ-mixing random variables. In particular, Wittmann＇s strong law of large numbers and Teicher＇s strong law of large nnum...We give some theorems of strong law of large numbers and complete convergence for sequences of φ-mixing random variables. In particular, Wittmann＇s strong law of large numbers and Teicher＇s strong law of large nnumbers for independent random variables are generalized to the case of φ -minxing random variables.展开更多
For two integers k and d with （k, d） = 1 and k≥2d, let G^dk be the graph with vertex set {0,1,…k - 1 } in which ij is an edge if and only if d≤｜ i -j I｜≤k - d. The circular chromatic number χc（G） of a graph...For two integers k and d with （k, d） = 1 and k≥2d, let G^dk be the graph with vertex set {0,1,…k - 1 } in which ij is an edge if and only if d≤｜ i -j I｜≤k - d. The circular chromatic number χc（G） of a graph G is the minimum of k/d for which G admits a homomorphism to G^dk. The relationship between χc（ G- v） and χc （G）is investigated. In particular, the circular chromatic number of G^dk - v for any vertex v is determined. Some graphs withx χc（G - v） =χc（G） - 1 for any vertex v and with certain properties are presented. Some lower bounds for the circular chromatic number of a graph are studied, and a necessary and sufficient condition under which the circular chromatic number of a graph attains the lower bound χ- 1 ＋ 1/α is proved, where χ is the chromatic number of G and a is its independence number.展开更多
If Goldbach’s conjecture is true, then for each prime number p there is at least one pair of primes symmetric with respect to p and whose sum is 2p. In the multiplicative number theory, covering the positive integers...If Goldbach’s conjecture is true, then for each prime number p there is at least one pair of primes symmetric with respect to p and whose sum is 2p. In the multiplicative number theory, covering the positive integers with primes, during the prime factorization, may be viewed as being the outcome of a parallel system which functions properly if and only if Euler’s formula of the product of the reciprocals of the primes is true. An exact formula for the number of primes less than or equal to an arbitrary bound is given. This formula may be implemented using Wolfram’s computer package Mathematica.展开更多
On the basis of the studies on the high unsteady aerodynamic mechanisms of the fruit fly hovering the aerodynamic advantages and disadvantages of the fruit fly flapping motion were analyzed. A new bionic flapping moti...On the basis of the studies on the high unsteady aerodynamic mechanisms of the fruit fly hovering the aerodynamic advantages and disadvantages of the fruit fly flapping motion were analyzed. A new bionic flapping motion was proposed to weaken the disadvantages and maintain the advantages, it may be used in the designing and manufacturing of the micro air vehicles （MAV＇s）. The translation of the new bionic flapping motion is the same as that of fruit fly flapping motion. However, the rotation of the new bionic flapping motion is different. It is not a pitching-up rotation as the fruit fly flapping motion, but a pitching-down rota- tion at the beginning and the end of a stroke. The numerical method of 3rd-order Roe scheme developed by Rogers was used to study these questions. The correctness of the numerical method and the computational program was justified by comparing the present CFD results of the fruit fly flapping motion in three modes, i.e., the advanced mode, the symmetrical mode and the delayed mode, with Dickinson＇s experimental results. They agreed with each other very well. Subsequently, the aerodynamic characteristics of the new bionic flapping motion in three modes were also numerically simulated, and were compared with those of the fruit fly flap- ping. The conclusions could be drawn that the high unsteady lift mechanism of the fruit fly hovering is also effectively utilized by this new bionic flapping. Compared with the fruit fly flapping, the unsteady drag of the new flapping decreases very much and the ratio of lift to drag increases greatly. And the great discrepancies among the mean lifts of three flapping modes of the fruit fly hovering are effectively smoothed in the new flapping. On the other hand, this new bionic flapping motion should be realized more easily. Finally, it must be pointed out that the above conclusions were just drawn for the hovering flapping motion. And the aerodynamic characteristics of the new bionic flapping motion in forward flight are going to be studied in the next step.展开更多
This article presents very original and relatively brief or very brief proofs about of two famous problems: 1) Are there any odd perfect numbers? and 2) “Fermat’s last theorem: A new proof of theorem and its general...This article presents very original and relatively brief or very brief proofs about of two famous problems: 1) Are there any odd perfect numbers? and 2) “Fermat’s last theorem: A new proof of theorem and its generalization”. They are achieved with elementary mathematics. This is why these proofs can be easily understood by any mathematician or anyone who knows basic mathematics. Note that, in both problems, proof by contradiction was used as a method of proof. The first of the two problems to date has not been resolved. Its proof is completely original and was not based on the work of other researchers. On the contrary, it was based on a simple observation that all natural divisors of a positive integer appear in pairs. The aim of the first work is to solve one of the unsolved, for many years, problems of the mathematics which belong to the field of number theory. I believe that if the present proof is recognized by the mathematical community, it may signal a different way of solving unsolved problems. For the second problem, it is very important the fact that it is generalized to an arbitrarily large number of variables. This generalization is essentially a new theorem in the field of the number theory. To the classical problem, two solutions are given, which are presented in the chronological order in which they were achieved. Note that the second solution is very short and does not exceed one and a half pages. This leads me to believe that Fermat, as a great mathematician was not lying and that he had probably solved the problem, as he stated in his historic its letter, with a correspondingly brief solution. To win the bet on the question of whether Fermat was telling truth or lying, go immediately to the end of this article before the General Conclusions.展开更多
In fairly good agreement with the consensus range of dark energy to matter this ratio of the critical density is suggested to be connected with the golden mean φ=0.6180339887, yielding for dark energy to matte...In fairly good agreement with the consensus range of dark energy to matter this ratio of the critical density is suggested to be connected with the golden mean φ=0.6180339887, yielding for dark energy to matter mass fractions .?Assuming the baryonic matter to be only 4.432%, the ratio of matter to baryonic matter would be , and further the ratio of dark matter to baryonic one . If one subtracts from the dark matter a contribution of antimatter with the same mass of baryonic matter, according to the antigravity theories of Villata respectively Hajdukovic, the remaining mass ratio would yield . Replacing the “Madelung” constant α of Villata’s “lattice universe” by φ, one reaches again 1 + φas the ratio of the repulsive mass contribution to the attractive one. Assuming instead of a 3D lattice a flat 2D one of rocksalt type, the numerical similarity between the Madelung constant and φ−1 could not be just coincidence. The proposed scaling of the cosmological mass fractions with the square of the most irrational universal number φmay indicate that the chaotic cosmological processes have reached a quite stable equilibrium. This may be confirmed by another, but similar representation of the mass constituents by the Archimedes’ constant π, giving for respectively for the dark components . However, the intimate connection of φ with its reciprocal may ignite the discussion whether our universe is intertwined with another universe or even part of a multiverse with the dark constituents contributed from there.展开更多
文摘目的：研究核糖体蛋白S15a（ribosomal protein S15a RPS15a）基因在胃癌及癌旁组织中表达差异，为进一步了解胃癌发生、发展的分子机制提供帮助。方法应用荧光定量PCR等方法进一步验证该基因在胃癌及癌旁组织中的表达差异，并在多种肿瘤细胞中的表达量进行比较。结果该基因在胃癌组织中的表达量高于其对应的癌旁组织，但在多种肿瘤细胞中的表达量无显著差异。结论 RPS15a基因在胃癌中呈高表达，说明其可能与细胞恶性生物学行为相关。在多种肿瘤细胞中表达量无显著差异，推测其可能在恶性肿瘤中的高表达具有普遍性。
基金Supported by the National Natural Science Foundation of China (10671149)
文摘We give some theorems of strong law of large numbers and complete convergence for sequences of φ-mixing random variables. In particular, Wittmann＇s strong law of large numbers and Teicher＇s strong law of large nnumbers for independent random variables are generalized to the case of φ -minxing random variables.
基金The National Natural Science Foundation of China(No.10671033)
文摘For two integers k and d with （k, d） = 1 and k≥2d, let G^dk be the graph with vertex set {0,1,…k - 1 } in which ij is an edge if and only if d≤｜ i -j I｜≤k - d. The circular chromatic number χc（G） of a graph G is the minimum of k/d for which G admits a homomorphism to G^dk. The relationship between χc（ G- v） and χc （G）is investigated. In particular, the circular chromatic number of G^dk - v for any vertex v is determined. Some graphs withx χc（G - v） =χc（G） - 1 for any vertex v and with certain properties are presented. Some lower bounds for the circular chromatic number of a graph are studied, and a necessary and sufficient condition under which the circular chromatic number of a graph attains the lower bound χ- 1 ＋ 1/α is proved, where χ is the chromatic number of G and a is its independence number.
文摘If Goldbach’s conjecture is true, then for each prime number p there is at least one pair of primes symmetric with respect to p and whose sum is 2p. In the multiplicative number theory, covering the positive integers with primes, during the prime factorization, may be viewed as being the outcome of a parallel system which functions properly if and only if Euler’s formula of the product of the reciprocals of the primes is true. An exact formula for the number of primes less than or equal to an arbitrary bound is given. This formula may be implemented using Wolfram’s computer package Mathematica.
基金The project supported by the National Natural Science Foundation of China10232010The project supported by the National Natural Science Foundation of China10032060The project supported by the National Natural Science Foundation of China90605005
文摘On the basis of the studies on the high unsteady aerodynamic mechanisms of the fruit fly hovering the aerodynamic advantages and disadvantages of the fruit fly flapping motion were analyzed. A new bionic flapping motion was proposed to weaken the disadvantages and maintain the advantages, it may be used in the designing and manufacturing of the micro air vehicles （MAV＇s）. The translation of the new bionic flapping motion is the same as that of fruit fly flapping motion. However, the rotation of the new bionic flapping motion is different. It is not a pitching-up rotation as the fruit fly flapping motion, but a pitching-down rota- tion at the beginning and the end of a stroke. The numerical method of 3rd-order Roe scheme developed by Rogers was used to study these questions. The correctness of the numerical method and the computational program was justified by comparing the present CFD results of the fruit fly flapping motion in three modes, i.e., the advanced mode, the symmetrical mode and the delayed mode, with Dickinson＇s experimental results. They agreed with each other very well. Subsequently, the aerodynamic characteristics of the new bionic flapping motion in three modes were also numerically simulated, and were compared with those of the fruit fly flap- ping. The conclusions could be drawn that the high unsteady lift mechanism of the fruit fly hovering is also effectively utilized by this new bionic flapping. Compared with the fruit fly flapping, the unsteady drag of the new flapping decreases very much and the ratio of lift to drag increases greatly. And the great discrepancies among the mean lifts of three flapping modes of the fruit fly hovering are effectively smoothed in the new flapping. On the other hand, this new bionic flapping motion should be realized more easily. Finally, it must be pointed out that the above conclusions were just drawn for the hovering flapping motion. And the aerodynamic characteristics of the new bionic flapping motion in forward flight are going to be studied in the next step.
文摘This article presents very original and relatively brief or very brief proofs about of two famous problems: 1) Are there any odd perfect numbers? and 2) “Fermat’s last theorem: A new proof of theorem and its generalization”. They are achieved with elementary mathematics. This is why these proofs can be easily understood by any mathematician or anyone who knows basic mathematics. Note that, in both problems, proof by contradiction was used as a method of proof. The first of the two problems to date has not been resolved. Its proof is completely original and was not based on the work of other researchers. On the contrary, it was based on a simple observation that all natural divisors of a positive integer appear in pairs. The aim of the first work is to solve one of the unsolved, for many years, problems of the mathematics which belong to the field of number theory. I believe that if the present proof is recognized by the mathematical community, it may signal a different way of solving unsolved problems. For the second problem, it is very important the fact that it is generalized to an arbitrarily large number of variables. This generalization is essentially a new theorem in the field of the number theory. To the classical problem, two solutions are given, which are presented in the chronological order in which they were achieved. Note that the second solution is very short and does not exceed one and a half pages. This leads me to believe that Fermat, as a great mathematician was not lying and that he had probably solved the problem, as he stated in his historic its letter, with a correspondingly brief solution. To win the bet on the question of whether Fermat was telling truth or lying, go immediately to the end of this article before the General Conclusions.
文摘In fairly good agreement with the consensus range of dark energy to matter this ratio of the critical density is suggested to be connected with the golden mean φ=0.6180339887, yielding for dark energy to matter mass fractions .?Assuming the baryonic matter to be only 4.432%, the ratio of matter to baryonic matter would be , and further the ratio of dark matter to baryonic one . If one subtracts from the dark matter a contribution of antimatter with the same mass of baryonic matter, according to the antigravity theories of Villata respectively Hajdukovic, the remaining mass ratio would yield . Replacing the “Madelung” constant α of Villata’s “lattice universe” by φ, one reaches again 1 + φas the ratio of the repulsive mass contribution to the attractive one. Assuming instead of a 3D lattice a flat 2D one of rocksalt type, the numerical similarity between the Madelung constant and φ−1 could not be just coincidence. The proposed scaling of the cosmological mass fractions with the square of the most irrational universal number φmay indicate that the chaotic cosmological processes have reached a quite stable equilibrium. This may be confirmed by another, but similar representation of the mass constituents by the Archimedes’ constant π, giving for respectively for the dark components . However, the intimate connection of φ with its reciprocal may ignite the discussion whether our universe is intertwined with another universe or even part of a multiverse with the dark constituents contributed from there.
