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Optimum Design for Shrink-fit Multi-layer Vessels under Ultrahigh Pressure Using Different Materials 被引量:6
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作者 YUAN Gexia LIU Hongzhao WANG Zhongrnin 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2010年第5期582-589,共8页
Multi-layer pressure vessels are widely used in every field of high pressure technology.For the purpose of enhancing a vessels' load bearing capacity,a beneficial process like shrink-fit is usually employed.However,f... Multi-layer pressure vessels are widely used in every field of high pressure technology.For the purpose of enhancing a vessels' load bearing capacity,a beneficial process like shrink-fit is usually employed.However,few documents on optimum design for multi-layer shrink-fit vessels made of different strength materials can be found,available data are mainly on two-layer vessels.In this paper,an optimum design approach is developed for shrink-fit multi-layer vessels under ultrahigh pressure by using different materials.Maximum shear stress theory is applied as design criteria.The inner and outer radii of a multi-layer vessel,as well as the material of each layer,are assumed to be known.The optimization mathematical model is,thereby,built.Lagrange multipliers method is required to obtain the optimal design formula of wall ratio(ratio of outer to inner radii) of each layer,from which the optimum formulas of shrinkage pressure and radial interference are derived with the superposition principle employed.These formulas are applicable for the optimization design of all multi-layer vessels made of different materials,or same materials.The formulas of the limit working pressure and the contact pressure show that the optimum wall ratio of each layer and limit working pressure are only related to all selected material strength and unrelated to the position of the layer placement in the vessel.However,shrinkage pressure is related to the position of the layer placement in the vessel.Optimization design of an open ended shrink-fit three-layer vessel using different materials and comparisons proved that the optimized multi-layer vessels have outstanding characteristics of small radial interference and are easier for assembly.When the stress of each layer is distributed more evenly and appropriately,the load bearing capability and safety of vessels are enhanced.Therefore,this design is material-saving and cost-effective,and has prospect of engineering application. 展开更多
关键词 multi-layer vessels Lagrange multiplier shrink-fit optimum interference maximum shear stress theory
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Intelligent Parameter Decision-Making and Multi-objective Prediction for Multi-layer and Multi-pass LDED Process
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作者 Li Yaguan Nie Zhenguo +2 位作者 Li Huilin Wang Tao Huang Qingxue 《稀有金属材料与工程》 北大核心 2026年第1期47-58,共12页
The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical m... The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical model height.The Taguchi method was employed to establish the correlations between process parameter combinations and multi-objective characterization of metal deposition morphology(height error and roughness).Results show that using the signal-to-noise ratio and grey relational analysis,the optimal parameter combination for multi-layer and multi-pass deposition is determined as follows:laser power of 800 W,powder feeding rate of 0.3 r/min,step distance of 1.6 mm,and scanning speed of 20 mm/s.Subsequently,a Genetic Bayesian-back propagation(GB-BP)network is constructed to predict multi-objective responses.Compared with the traditional back propagation network,the GB-back propagation network improves the prediction accuracy of height error and surface roughness by 43.14%and 71.43%,respectively.This network can accurately predict the multi-objective characterization of morphological quality of multi-layer and multi-pass metal deposited parts. 展开更多
关键词 multi-layer and multi-pass laser cladding Taguchi method grey relational analysis GB-BP network
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Multi-layer multi-pass friction rolling additive manufacturing of Al alloy:Toward complex large-scale high-performance components 被引量:1
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作者 Haibin Liu Run Hou +2 位作者 Chenghao Wu Ruishan Xie Shujun Chen 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第2期425-438,共14页
At present,the emerging solid-phase friction-based additive manufacturing technology,including friction rolling additive man-ufacturing(FRAM),can only manufacture simple single-pass components.In this study,multi-laye... At present,the emerging solid-phase friction-based additive manufacturing technology,including friction rolling additive man-ufacturing(FRAM),can only manufacture simple single-pass components.In this study,multi-layer multi-pass FRAM-deposited alumin-um alloy samples were successfully prepared using a non-shoulder tool head.The material flow behavior and microstructure of the over-lapped zone between adjacent layers and passes during multi-layer multi-pass FRAM deposition were studied using the hybrid 6061 and 5052 aluminum alloys.The results showed that a mechanical interlocking structure was formed between the adjacent layers and the adja-cent passes in the overlapped center area.Repeated friction and rolling of the tool head led to different degrees of lateral flow and plastic deformation of the materials in the overlapped zone,which made the recrystallization degree in the left and right edge zones of the over-lapped zone the highest,followed by the overlapped center zone and the non-overlapped zone.The tensile strength of the overlapped zone exceeded 90%of that of the single-pass deposition sample.It is proved that although there are uneven grooves on the surface of the over-lapping area during multi-layer and multi-pass deposition,they can be filled by the flow of materials during the deposition of the next lay-er,thus ensuring the dense microstructure and excellent mechanical properties of the overlapping area.The multi-layer multi-pass FRAM deposition overcomes the limitation of deposition width and lays the foundation for the future deposition of large-scale high-performance components. 展开更多
关键词 aluminum alloy additive manufacturing SOLID-STATE friction stir welding multi-layer multi-pass
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Advances in artificial blood vessels:Exploring materials,preparation,and functionality 被引量:1
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作者 Feng Wang Mengdi Liang +5 位作者 Bei Zhang Weiqiang Li Xianchen Huang Xicheng Zhang Kaili Chen Gang Li 《Journal of Materials Science & Technology》 2025年第16期225-256,共32页
Cardiovascular disease(CVD)is a major global health challenge,which causes significant illness and death worldwide.These include a range of conditions that affect the heart and blood vessels,including coro-nary artery... Cardiovascular disease(CVD)is a major global health challenge,which causes significant illness and death worldwide.These include a range of conditions that affect the heart and blood vessels,including coro-nary artery disease,stroke,peripheral artery disease,and heart failure.Despite advances in medicine and healthcare delivery,CVD continues to have a serious impact on individuals,families,and the healthcare system.This review begins by delineating the merits and demerits of commonly employed synthetic and natural materials for artificial blood vessels.It delves into various techniques commonly employed in the fabrication of artificial blood vessels,encompassing advanced textile technologies,electrospinning,ther-mally induced phase separation,and 3D printing.The review critically analyzes the attributes of different preparation methodologies alongside the latest advancements in research.The review also outlines the requisite performance requirements for artificial blood vessels,which encompass robust mechanical prop-erties,appropriate porosity,exceptional compatibility,and antibacterial attributes.It provides a succinct overview of ongoing effort s in vascular functionalization,particularly emphasizing thrombus mitigation,promotion of endothelialization,and enhancement of nitric oxide production.The review finally encap-sulates the primary challenges confronting vascular grafts and prospective avenues for future research. 展开更多
关键词 Artificial blood vessels Materials choice Preparation techniques Performance requirements FUNCTIONALIZATION
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A Multi-Layer Progressive Analysis Method for Collision Energy Flow in Rail Trains
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作者 Jingke Zhang Tao Zhu +4 位作者 Xiaorui Wang Bing Yang Shoune Xiao Guangwu Yang Yuru Li 《Chinese Journal of Mechanical Engineering》 2025年第5期425-439,共15页
The huge impact kinetic energy cannot be quickly dissipated by the energy-absorbing structure and transferred to the other vehicle through the car body structure,which will cause structural damage and threaten the liv... The huge impact kinetic energy cannot be quickly dissipated by the energy-absorbing structure and transferred to the other vehicle through the car body structure,which will cause structural damage and threaten the lives of the occupants.Therefore,it is necessary to understand the laws of energy conversion,dissipation and transfer during train collisions.This study proposes a multi-layer progressive analysis method of energy flow during train collisions,considering the characteristics of the train.In this method,the train collision system is divided into conversion,dissipation,and transfer layers from the perspective of the train,collision interface,and car body structure to analyze the energy conversion,dissipation and transfer characteristics.Taking the collision process of a rail train as an example,a train collision energy transfer path analysis model was established based on power flow theory.The results show that when the maximum mean acceleration of the vehicle meets the standard requirements,the jerk may exceed the allowable limit of the human body,and there is a risk of injury to the occupants of a secondary collision.The decay rate of the collision energy along the direction of train operation reaches 79%.As the collision progresses,the collision energy gradually converges in the structure with holes,and the structure deforms when the gathered energy is greater than the maximum energy the structure can withstand.The proposed method helps to understand the train collision energy flow law and provides theoretical support for the train crashworthiness design in the future. 展开更多
关键词 Train Cllision multi-layer Progression Energy Flow Energy Conversion Energy Dissipation Energy Transfer
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Intrusion Detection Model on Network Data with Deep Adaptive Multi-Layer Attention Network(DAMLAN)
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作者 Fatma S.Alrayes Syed Umar Amin +2 位作者 Nada Ali Hakami Mohammed K.Alzaylaee Tariq Kashmeery 《Computer Modeling in Engineering & Sciences》 2025年第7期581-614,共34页
The growing incidence of cyberattacks necessitates a robust and effective Intrusion Detection Systems(IDS)for enhanced network security.While conventional IDSs can be unsuitable for detecting different and emerging at... The growing incidence of cyberattacks necessitates a robust and effective Intrusion Detection Systems(IDS)for enhanced network security.While conventional IDSs can be unsuitable for detecting different and emerging attacks,there is a demand for better techniques to improve detection reliability.This study introduces a new method,the Deep Adaptive Multi-Layer Attention Network(DAMLAN),to boost the result of intrusion detection on network data.Due to its multi-scale attention mechanisms and graph features,DAMLAN aims to address both known and unknown intrusions.The real-world NSL-KDD dataset,a popular choice among IDS researchers,is used to assess the proposed model.There are 67,343 normal samples and 58,630 intrusion attacks in the training set,12,833 normal samples,and 9711 intrusion attacks in the test set.Thus,the proposed DAMLAN method is more effective than the standard models due to the consideration of patterns by the attention layers.The experimental performance of the proposed model demonstrates that it achieves 99.26%training accuracy and 90.68%testing accuracy,with precision reaching 98.54%on the training set and 96.64%on the testing set.The recall and F1 scores again support the model with training set values of 99.90%and 99.21%and testing set values of 86.65%and 91.37%.These results provide a strong basis for the claims made regarding the model’s potential to identify intrusion attacks and affirm its relatively strong overall performance,irrespective of type.Future work would employ more attempts to extend the scalability and applicability of DAMLAN for real-time use in intrusion detection systems. 展开更多
关键词 Intrusion detection deep adaptive networks multi-layer attention DAMLAN network security anomaly detection
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Application of Bundle Nursing Strategy in the Maintenance of Difficult Blood Vessels for Long-term Hemodialysis Patients
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作者 Yelin Wang Liangmei Fei 《Journal of Clinical and Nursing Research》 2025年第5期297-303,共7页
Objective:To study the application effect of bundle nursing strategy in the maintenance of difficult blood vessels for long-term hemodialysis patients.Methods:A prospective study was conducted on 40 long-term hemodial... Objective:To study the application effect of bundle nursing strategy in the maintenance of difficult blood vessels for long-term hemodialysis patients.Methods:A prospective study was conducted on 40 long-term hemodialysis patients admitted from January 2024 to January 2025.The patients were randomly divided into a control group(20 cases)and an observation group(20 cases)using computer random sampling.The control group received routine nursing for difficult blood vessels,while the observation group received a bundle nursing strategy for difficult blood vessels.The self-care ability,complication rate,and nursing satisfaction were compared between the two groups.Results:After nursing,the self-care ability score of the observation group was higher than that of the control group(P<0.05).The complication rate in the observation group was lower than that in the control group(P<0.05).The nursing satisfaction in the observation group was higher than that in the control group(P<0.05).Conclusion:The application of the bundle nursing strategy in the maintenance of difficult blood vessels for long-term hemodialysis patients is beneficial for improving self-care ability,reducing complications,and increasing patient satisfaction with nursing services. 展开更多
关键词 Long-term hemodialysis Difficult blood vessels Routine nursing Bundle nursing strategy
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General analytical solutions for one-dimensional diffusion of degradable organic contaminant in the multi-layered media containing geomembranes
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作者 JIANG Wen-hao GE Shang-qi LI Jiang-shan 《Journal of Central South University》 2025年第10期3895-3910,共16页
In practical engineering construction,multi-layered barriers containing geomembranes are extensively applied to retard the migration of pollutants.However,the associated analytical theory on pollutants diffusion still... In practical engineering construction,multi-layered barriers containing geomembranes are extensively applied to retard the migration of pollutants.However,the associated analytical theory on pollutants diffusion still needs to be further improved.In this work,general analytical solutions are derived for one-dimensional diffusion of degradable organic contaminant(DOC)in the multi-layered media containing geomembranes under a time-varying concentration boundary condition,where the variable substitution and separated variable approaches are employed.These analytical solutions with clear expressions can be used not only to study the diffusion behaviors of DOC in bottom and vertical composite barrier systems,but also to verify other complex numerical models.The proposed general analytical solutions are then fully validated via three comparative analyses,including comparisons with the experimental measurements,an existing analytical solution,and a finite-difference solution.Ultimately,the influences of different factors on the composite cutoff wall’s(CCW,which consists of two soil-bentonite layers and a geomembrane)service performance are investigated through a composite vertical barrier system as the application example.The findings obtained from this investigation can provide scientific guidance for the barrier performance evaluation and the engineering design of CCWs.This application example also exhibits the necessity and effectiveness of the developed analytical solutions. 展开更多
关键词 general analytical solutions degradable organic contaminant diffusion behavior multi-layered media containing geomembranes composite barrier system
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Effect of tempering temperature on microstructure and mechanical properties of flange forgings for high-pressure hydrogen storage vessels
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作者 Xin-jun Sun Kang-feng Zhu +5 位作者 Hai-dong Jia Bo Zhang Ba Li Wan-bo Dou Xiao-kai Liang Cai-fu Yang 《Journal of Iron and Steel Research International》 2025年第9期2893-2906,共14页
The mechanical properties,microstructure and second phase precipitation behavior of flange forgings for high-pressure hydrogen storage vessels at different tempering temperatures(620–700℃)were studied.The results sh... The mechanical properties,microstructure and second phase precipitation behavior of flange forgings for high-pressure hydrogen storage vessels at different tempering temperatures(620–700℃)were studied.The results showed that when tempered at 620–680°C,the main microstructure of the test steel was tempered sorbite,and the main microstructure of tempered steel changed to martensite at 700℃.At 700℃,the dislocation density increased and some retained austenite existed.With the tempering temperature increasing,the yield strength showed a decreasing trend,the formation of fresh martensite made the tensile strength first decrease and then increase slightly,the impact energy at−40℃increased first and then decreased,and the impact energy at 660℃had the maximum value.The precipitates of MC type were mainly(Mo,V,Ti)C.The test steel had excellent strength and toughness matching at 660℃tempering,the tensile strength at different cross section locations was above 750 MPa,the impact energy was above 200 J at−40℃,and the relative percentage reduction of area(ZH2/ZN2)was above 75%at hydrogen environment of 6.3 MPa. 展开更多
关键词 FORGING Hydrogen storage pressure vessel Tempering temperature MICROSTRUCTURE Mechanical property
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An improved model for predicting thermal contact resistance at multi-layered rock interface
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作者 WEN Min-jie XIE Jia-hao +4 位作者 LI Li-chen TIAN Yi EL NAGGAR M.Hesham MEI Guo-xiong WU Wen-bing 《Journal of Central South University》 2025年第1期229-243,共15页
This study proposes a general imperfect thermal contact model to predict the thermal contact resistance at the interface among multi-layered composite structures.Based on the Green-Lindsay(GL)thermoelastic theory,semi... This study proposes a general imperfect thermal contact model to predict the thermal contact resistance at the interface among multi-layered composite structures.Based on the Green-Lindsay(GL)thermoelastic theory,semi analytical solutions of temperature increment and displacement of multi-layered composite structures are obtained by using the Laplace transform method,upon which the effects of thermal resistance coefficient,partition coefficient,thermal conductivity ratio and heat capacity ratio on the responses are studied.The results show that the generalized imperfect thermal contact model can realistically describe the imperfect thermal contact problem.Accordingly,it may degenerate into other thermal contact models by adjusting the thermal resistance coefficient and partition coefficient. 展开更多
关键词 multi-layered structures general thermal contact model thermal contact resistance GL thermoelastic theory Laplace transform
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Numerical Exploration on Load Transfer Characteristics and Optimization of Multi-Layer Composite Pavement Structures Based on Improved Transfer Matrix Method
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作者 Guo-Zhi Li Hua-Ping Wang +2 位作者 Si-Kai Wang Jing-Cheng Zhou Ping Xiang 《Computer Modeling in Engineering & Sciences》 2025年第12期3165-3195,共31页
Transportation structures such as composite pavements and railway foundations typically consist of multi-layered media designed to withstand high bearing capacity.A theoretical understanding of load transfer mechanism... Transportation structures such as composite pavements and railway foundations typically consist of multi-layered media designed to withstand high bearing capacity.A theoretical understanding of load transfer mechanisms in these multi-layer composites is essential,as it offers intuitive insights into parametric influences and facilitates enhanced structural performance.This paper employs an improved transfer matrix method to address the limitations of existing theoretical approaches for analyzing multi-layer composite structures.By establishing a twodimensional composite pavement model,it investigates load transfer characteristics and validates the accuracy through finite element simulation.The proposed method offers a straightforward analytical approach for examining internal interactions between structural layers.Case studies indicate that the concrete surface layer is the main load-bearing layer for most vertical normal and shear stresses.The soil base layer reduces the overall mechanical response of the substructure,while horizontal actions increase the risk of interfacial slip and cracking.Structural optimization analysis demonstrates that increasing the thickness of the concrete surface layer,enhancing the thickness and stiffness of the soil base layer,or incorporating gradient layers can significantly mitigate these risks of interfacial slip and cracking.The findings of this study can guide the optimization design,parameter analysis,and damage prevention of multi-layer composite structures. 展开更多
关键词 multi-layer composite pavement improved theoretical analysis transfer matrix method structural optimization damage prevention
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Routing cost-integrated intelligent handover strategy for multi-layer LEO mega-constellation networks
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作者 Zhenglong YIN Quan CHEN +2 位作者 Lei YANG Yong ZHAO Xiaoqian CHEN 《Chinese Journal of Aeronautics》 2025年第6期487-500,共14页
Low Earth Orbit(LEO)mega-constellation networks,exemplified by Starlink,are poised to play a pivotal role in future mobile communication networks,due to their low latency and high capacity.With the massively deployed ... Low Earth Orbit(LEO)mega-constellation networks,exemplified by Starlink,are poised to play a pivotal role in future mobile communication networks,due to their low latency and high capacity.With the massively deployed satellites,ground users now can be covered by multiple visible satellites,but also face complex handover issues with such massive high-mobility satellites in multi-layer.The end-to-end routing is also affected by the handover behavior.In this paper,we propose an intelligent handover strategy dedicated to multi-layer LEO mega-constellation networks.Firstly,an analytic model is utilized to rapidly estimate the end-to-end propagation latency as a key handover factor to construct a multi-objective optimization model.Subsequently,an intelligent handover strategy is proposed by employing the Dueling Double Deep Q Network(D3QN)-based deep reinforcement learning algorithm for single-layer constellations.Moreover,an optimal crosslayer handover scheme is proposed by predicting the latency-jitter and minimizing the cross-layer overhead.Simulation results demonstrate the superior performance of the proposed method in the multi-layer LEO mega-constellation,showcasing reductions of up to 8.2%and 59.5%in end-to-end latency and jitter respectively,when compared to the existing handover strategies. 展开更多
关键词 multi-layer LEO mega-constellation networks HANDOVER Routing cost Dueling Double Deep Q Network(D3QN)
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CT-MFENet:Context Transformer and Multi-Scale Feature Extraction Network via Global-Local Features Fusion for Retinal Vessels Segmentation
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作者 SHAO Dangguo YANG Yuanbiao +1 位作者 MA Lei YI Sanli 《Journal of Shanghai Jiaotong university(Science)》 2025年第4期668-682,共15页
Segmentation of the retinal vessels in the fundus is crucial for diagnosing ocular diseases.Retinal vessel images often suffer from category imbalance and large scale variations.This ultimately results in incomplete v... Segmentation of the retinal vessels in the fundus is crucial for diagnosing ocular diseases.Retinal vessel images often suffer from category imbalance and large scale variations.This ultimately results in incomplete vessel segmentation and poor continuity.In this study,we propose CT-MFENet to address the aforementioned issues.First,the use of context transformer(CT)allows for the integration of contextual feature information,which helps establish the connection between pixels and solve the problem of incomplete vessel continuity.Second,multi-scale dense residual networks are used instead of traditional CNN to address the issue of inadequate local feature extraction when the model encounters vessels at multiple scales.In the decoding stage,we introduce a local-global fusion module.It enhances the localization of vascular information and reduces the semantic gap between high-and low-level features.To address the class imbalance in retinal images,we propose a hybrid loss function that enhances the segmentation ability of the model for topological structures.We conducted experiments on the publicly available DRIVE,CHASEDB1,STARE,and IOSTAR datasets.The experimental results show that our CT-MFENet performs better than most existing methods,including the baseline U-Net. 展开更多
关键词 retinal vessel segmentation context transformer(CT) multi-scale dense residual hybrid loss function global-local fusion
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Experimental investigation on dynamic stab resistance of highperformance multi-layer textile materials
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作者 Mulat Alubel Abtew François Boussu +1 位作者 Irina Cristian Bekinew Kitaw Dejene 《Defence Technology(防务技术)》 2025年第5期1-14,共14页
Stab-resistant textiles play a critical role in personal protection,necessitating a deeper understanding of how structural and layering factors influence their performance.The current study experimentally examines the... Stab-resistant textiles play a critical role in personal protection,necessitating a deeper understanding of how structural and layering factors influence their performance.The current study experimentally examines the effects of textile structure,layering,and ply orientation on the stab resistance of multi-layer textiles.Three 3D warp interlock(3DWI)structures({f1},{f2},{f3})and a 2D woven fabric({f4}),all made of high-performance p-aramid yarns,were engineered and manufactured.Multi-layer specimens were prepared and subjected to drop-weight stabbing tests following HOSBD standards.Stabbing performance metrics,including Depth of Trauma(DoT),Depth of Penetration(DoP),and trauma deformation(Ymax,Xmax),were investigated and analyzed.Statistical analyses(Two-and One-Way ANOVA)indicated that fabric type and layer number significantly impacted DoP(P<0.05),while ply orientation significantly affected DoP(P<0.05)but not DoT(P>0.05).Further detailed analysis revealed that 2D woven fabrics exhibited greater trauma deformation than 3D WIF structures.Increasing the number of layers reduced both DoP and DoT across all fabric structures,with f3 demonstrating the best performance in multi-layer configurations.Aligned ply orientations also enhanced stab resistance,underscoring the importance of alignment in dissipating impact energy. 展开更多
关键词 2D/3D woven fabrics High-performance fibers Protective textiles multi-layer panels Impact ply orientation Dynamic stab resistance
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Path Planning for Emergency Response and Rescue Vessels in Inland Rivers by Improved Artificial Potential Field Algorithms
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作者 Jingyu Yu Qingyu Shi +2 位作者 Wei Lin Jingfeng Wang Yuxue Pu 《哈尔滨工程大学学报(英文版)》 2025年第6期1291-1303,共13页
Frequent flood disasters caused by climate change may lead to tremendous economic and human losses along inland waterways.Emergency response and rescue vessels(ERRVs)play an essential role in minimizing losses and pro... Frequent flood disasters caused by climate change may lead to tremendous economic and human losses along inland waterways.Emergency response and rescue vessels(ERRVs)play an essential role in minimizing losses and protecting lives and property.However,the path planning of ERRVs has mainly depended on expert experiences instead of rational decision making.This paper proposes an improved artificial potential field(APF)algorithm to optimize the shortest path for ERRVs in the rescue process.To verify the feasibility of the proposed model,eight tests were carried out in two water areas of the Yangtze River.The results showed that the improved APF algorithm was efficient with fewer iterations and that the response time of path planning was reduced to around eight seconds.The improved APF algorithm performed better in the ERRV’s goal achievement,compared with the traditional algorithm.The path planning method for ERRVs proposed in this paper has theoretical and practical value in flood relief.It can be applied in the emergency management of ERRVs to accelerate flood management efficiency and improve capacity to prevent,mitigate,and relieve flood disasters. 展开更多
关键词 Emergency response and rescue vessels(ERRVs) Artificial potential field(APF)algorithm Path planning Emergency management Inland rivers
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Targeting the brain’s glymphatic pathway:A novel therapeutic approach for cerebral small vessel disease 被引量:1
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作者 Yuhui Ma Yan Han 《Neural Regeneration Research》 2026年第2期433-442,共10页
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels,often leading to stroke and dementia.Due to its diverse etiologies and complex pathological me... Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels,often leading to stroke and dementia.Due to its diverse etiologies and complex pathological mechanisms,preventing and treating cerebral small vessel vasculopathy is challenging.Recent studies have shown that the glymphatic system plays a crucial role in interstitial solute clearance and the maintenance of brain homeostasis.Increasing evidence also suggests that dysfunction in glymphatic clearance is a key factor in the progression of cerebral small vessel disease.This review begins with a comprehensive introduction to the structure,function,and driving factors of the glymphatic system,highlighting its essential role in brain waste clearance.Afterwards,cerebral small vessel disease was reviewed from the perspective of the glymphatic system,after which the mechanisms underlying their correlation were summarized.Glymphatic dysfunction may lead to the accumulation of metabolic waste in the brain,thereby exacerbating the pathological processes associated with cerebral small vessel disease.The review also discussed the direct evidence of glymphatic dysfunction in patients and animal models exhibiting two subtypes of cerebral small vessel disease:arteriolosclerosis-related cerebral small vessel disease and amyloid-related cerebral small vessel disease.Diffusion tensor image analysis along the perivascular space is an important non-invasive tool for assessing the clearance function of the glymphatic system.However,the effectiveness of its parameters needs to be enhanced.Among various nervous system diseases,including cerebral small vessel disease,glymphatic failure may be a common final pathway toward dementia.Overall,this review summarizes prevention and treatment strategies that target glymphatic drainage and will offer valuable insight for developing novel treatments for cerebral small vessel disease. 展开更多
关键词 AQUAPORIN-4 ASTROCYTES cerebral amyloid angiopathy cerebral small vessel disease cerebrospinal fluid diffusion tensor image analysis along the perivascular space glymphatic system interstitial fluid perivascular space therapeutic strategies
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Carbon Footprint and Economic Analysis of LNG-fueled Fishing Vessel Using Real Engine Performance Simulation
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作者 Momir Sjerić Maja Perčić +1 位作者 Ivana Jovanović Nikola Vladimir 《哈尔滨工程大学学报(英文版)》 2026年第1期259-276,共18页
Analysis of the environmental and economic performance of fishing vessels has received limited attention compared with other ship types despite their notable contribution to global greenhouse gas(GHG)emissions.This st... Analysis of the environmental and economic performance of fishing vessels has received limited attention compared with other ship types despite their notable contribution to global greenhouse gas(GHG)emissions.This study evaluates the carbon footprint(CF)and economic viability of a liquefied natural gas(LNG)-fueled fishing vessel,using real engine operation simulations to provide precise and dynamic evaluation of fuel consumption and GHG emissions.Operational profiles are obtained through the utilization of onboard monitoring systems,whereas engine performance is simulated using the 1D/0D AVL Boost^(TM)model.Life cycle assessment(LCA)is conducted to quantify the environmental impact,whereas life cycle cost assessment(LCCA)is performed to analyze the profitability of LNG as an alternative fuel.The potential impact of the future fuel price uncertainties is addressed using Monte Carlo simulations.The LCA findings indicate that LNG has the potential to reduce the CF of the vessel by 14%to 16%,in comparison to a diesel power system configuration that serves as the baseline scenario.The LCCA results further indicate that the total cost of an LNG-powered ship is lower by 9.5%-13.8%,depending on the share of LNG and pilot fuels.This finding highlights the potential of LNG to produce considerable environmental benefits while addressing economic challenges under diverse operational and fuel price conditions. 展开更多
关键词 1D/0D simulation Carbon footprint Fishing vessels Life cycle assessment Life cycle cost assessment Liquefied natural gas
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Studies on the Molecular Structure of Vessels in Secondary Xylem of Stem from Three Carambola Varieties 被引量:2
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作者 陈燕 袁长春 陈小婷 《Agricultural Science & Technology》 CAS 2008年第4期99-103,156,共6页
[Objective] The aim of this study was to provide the theoretical basis for variety identification of carambola and pomiculture.[Method] The molecular structure of vessels in stem secondary xylem from three carambola v... [Objective] The aim of this study was to provide the theoretical basis for variety identification of carambola and pomiculture.[Method] The molecular structure of vessels in stem secondary xylem from three carambola varieties of Malaysia 8,Misi and Malaysia B17 were studied by cell image analysis system and microphotography.[Result] The molecular structure of vessels in stem secondary xylem from carambola was as follows:the first type had tails in two ends,the second type had tail in one end,and the third type had no tails in two ends.The average length of vessel elements was from 328.88 to 366.09 μm,while its average width was from 44.61 to 52.43 μm.Most of the end wall was simple perforation plates,while the alternate-opposite pitting was the major forms of pitting.[Conclusion] Most characteristics of vessel elements from carambola were evolutionary characters of vessel elements in the process of phylogeny,but there were more primitive characters,for example,both two ends of vessel had tails or just one end had tail,and end wall was inclined.The molecular structure of vessel from carambola was in accordance with its ecological adaptability,and the growth characteristics of different varieties were also in accordance with the difference of molecular structure of vessel. 展开更多
关键词 CARAMBOLA vessel elements Microstructure
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穿支皮瓣choke vessels新生的研究进展 被引量:7
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作者 李红 陈世新 +1 位作者 唐茂林 毛以华 《中国临床解剖学杂志》 CSCD 北大核心 2016年第6期711-712,715,共3页
大量研究资料显示:每一皮肤穿支均有一个明确的供血范围,并与周围其它穿支的分支相互吻合形成血管网,即choke vessels。作为血管体间桥梁结构的choke vessels在跨区皮瓣的设计和切取方面起到十分重要的作用。近年来,有关穿支皮瓣跨区... 大量研究资料显示:每一皮肤穿支均有一个明确的供血范围,并与周围其它穿支的分支相互吻合形成血管网,即choke vessels。作为血管体间桥梁结构的choke vessels在跨区皮瓣的设计和切取方面起到十分重要的作用。近年来,有关穿支皮瓣跨区供血的基础研究-[1-3]和临床报道-[4-6]屡见不鲜,而本文就其中与choke vessels新生相关的研究综述如下。 展开更多
关键词 穿支皮瓣 CHOKE vessels 血管网 血管发生 桥梁结构 供区 动脉灌注 静脉回流 血管内皮细胞 血缺氧
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Choke Vessels扩展的研究进展 被引量:1
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作者 蒙旭昌 昝涛 李青峰 《组织工程与重建外科杂志》 2017年第1期48-50,共3页
穿支皮瓣是创伤修复的研究热点,穿支皮瓣研究的重点和难点则在于choke vessels。我们对近年来choke vessels扩展研究的相关文献进行综述,目前的研究主要聚焦于形态学的描述,其扩张机制很可能是剪切力变化,激活TRPV4,通过NF-kb通路而导致... 穿支皮瓣是创伤修复的研究热点,穿支皮瓣研究的重点和难点则在于choke vessels。我们对近年来choke vessels扩展研究的相关文献进行综述,目前的研究主要聚焦于形态学的描述,其扩张机制很可能是剪切力变化,激活TRPV4,通过NF-kb通路而导致choke vessels扩张。 展开更多
关键词 CHOKE vessels 穿支皮瓣 动脉生成 扩展
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