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Multidisciplinary and multi-fidelity coupling methods in aircraft engine simulations
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作者 YANG Xin XIE Pengfu +2 位作者 DONG Xuezhi HE Ai TAN Chunqing 《推进技术》 北大核心 2025年第5期1-12,共12页
To address the limitations of existing coupling methods in aero-engine system simulation,which fail to adaptively adjust iterative parameters and coupling relationships,which can result in low efficiency and in⁃stabil... To address the limitations of existing coupling methods in aero-engine system simulation,which fail to adaptively adjust iterative parameters and coupling relationships,which can result in low efficiency and in⁃stability,this study introduces a‘Dynamic Event-Driven Co-Simulation’algorithm integrated with decision tree algorithms.This algorithm separates the overall coupling relationships and the main solver from the primary mod⁃el,utilizing a dynamic event monitoring module to adaptively adjust simulation strategies,including iteration pa⁃rameters,coupling relationships,and convergence criteria.This facilitates efficient adaptive simulations of dy⁃namic events while balancing solution accuracy and computational efficiency.The research focuses on a twinshaft turbofan engine,establishing six system-level models that encompass overall performance and various sub⁃systems based on three coupling methods,along with a multidisciplinary multi-fidelity simulation framework in⁃corporating a 3D CFD nozzle model.The study tests both model exchange and coupled simulation methods under a 14 s transient acceleration and deceleration scenario.In a 100%throttle condition,a high-fidelity nozzle model is used to analyze the sensitivity of different convergence criteria on computational efficiency and accuracy.Re⁃sults indicate that the accuracy and efficiency achieved with this method are comparable to those of PROOSIS soft⁃ware(18 s and 35 s,respectively),while being 71%more efficient than Simulink software(62 s and 120 s,re⁃spectively).Furthermore,appropriately relaxing the convergence criteria for the 0D model(from 10-6 to 10-4)while enhancing those for the 3D model(from 3000 steps to 6000 steps)can effectively balance computational accuracy and efficiency. 展开更多
关键词 AERO-ENGINE multi-fidelity simulation Overall performance CO-SIMULATION Integrated model Zooming strategy
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A relay-based probabilistic prediction model for multi-fidelity scenarios in total pressure loss of a compressor cascade with micro-textured surfaces
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作者 Liyue WANG Cong WANG +2 位作者 Xinyue LAN Haochen ZHANG Gang SUN 《Chinese Journal of Aeronautics》 2026年第1期55-65,共11页
The micro-riblet structures have been demonstrated effective in controlling the Total Pressure Loss(TPL)of aero-engine blades.However,due to the considerable scale gap between micro-texture and an actual aero-engine b... The micro-riblet structures have been demonstrated effective in controlling the Total Pressure Loss(TPL)of aero-engine blades.However,due to the considerable scale gap between micro-texture and an actual aero-engine blade,wind tunnel tests and numerical simulations with massive grids directly describing the global flow field are costly for aerodynamic evaluation.Furthermore,the fine micro surface structure brings unavoidable manufacturing errors,and the probability prediction contributes to gaining the confidence interval of the results.Therefore,a novel relay-based probabilistic model for multi-fidelity scenarios in the TPL prediction of a compressor cascade with micro-riblet surfaces is proposed to trade off accuracy and efficiency.Combined with the low-fidelity flow data generated by an aerodynamic solution strategy using the boundary surrogate model and the high-fidelity flow data from the experiment,the relay-based modeling has been achieved through knowledge transferring,and the confidence interval can be provided by the Gaussian Process Regression(GPR)model.The TPL of compressor cascades with micro-riblet surfaces under different surface structures at March number Ma=0.64,0.74,0.84 have been evaluated using the Relay-Based Probabilistic(RBP)model.The results illustrate that the RBP model could provide higher accuracy than the Single-Fidelity-Data-Driven(SFDD)prediction model,which show the promising potential of multi-fidelity scenarios data fusion in the aerodynamic evaluation of multi-scale configurations. 展开更多
关键词 Knowledge transfer Micro-riblet multi-fidelity surrogate Probability prediction model Total pressure loss
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A Cost-Effective Approach to Precisely Estimate Singlet-Triplet Energy Gaps in MR-TADF Molecules:Combining Delta Self-Consistent Field and Time-Dependent Density Functional Theory Methods
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作者 Qian Jina Dong Wang 《Chinese Journal of Chemical Physics》 2026年第1期41-50,I0021-I0032,I0042,共23页
As a novel class of purely organic fluores-cent materials,multiple resonance thermal-ly activated delayed fluorescence(MR-TADF)compounds hold significant promise for next-generation display technologies.The efficiency... As a novel class of purely organic fluores-cent materials,multiple resonance thermal-ly activated delayed fluorescence(MR-TADF)compounds hold significant promise for next-generation display technologies.The efficiency of exciton utilization and the overall performance of organic light-emit-ting devices are closely linked to the singlet-triplet energy gap(ΔE_(ST))of MR-TADF emitters.Identifying an economic and accu-rate theoretical approach to predictΔE_(ST)would be beneficial for high-throughput screening and facilitate the inverse design of MR-TADF molecules.In this study,we evaluated the S_(1)state energy(E(S_(1))),T_(1)state ener-gy(E(T_(1))),andΔE_(ST)using three different physical interpretations:adiabatic excitation ener-gy,vertical absorption energy,and vertical emission energy.We employed the time-depen-dent density functional theory(TDDFT)and delta self-consistent field(ΔSCF)methods to calculate E(S_(1)),E(T_(1)),andΔE_(ST)for 20 MR-TADF molecules reported in the literature.We compared these calculated values with experimental data obtained from fluorescence spec-troscopy at room-temperature(or 77 K)and phosphorescence spectroscopy conducted at 77 K.Our findings indicate that the vertical absorption energy at the S0 state minimum,deter-mined by theΔSCF method,accurately predicts the S_(1)state energy.Similarly,the vertical absorption energy at the S0 state minimum,calculated using the TDDFT method,effectively predicts the T_(1)state energy.TheΔE_(ST)derived from the difference between these two excita-tion energies exhibited the smallest mean absolute error of only 0.039 eV compared to the ex-perimental values.This combination represents the most accurate and cost-effective method reported to date for predicting theΔE_(ST)of MR-TADF molecules,and can be integrated into AI-driven inverse design workflows for new emitters. 展开更多
关键词 Organic light-emitting diode Multiple resonance thermally activated delayed fluorescence emitter Single-triplet energy gap Delta self-consistent field method Time-de-pendent density functional theory method
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Healthcare professionals’perspectives on disclosure of diagnosis and related issues in childhood cancer:A mixed methods systematic review
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作者 Run Xie Xiaoyan Huang +4 位作者 Yiran Du Ying Gu Qiongfang Kang Hongsheng Wang Daqian Zhu 《International Journal of Nursing Sciences》 2026年第1期96-104,I0006,共10页
Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of... Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process. 展开更多
关键词 Communication CANCER DISCLOSURE Healthcare professionals Mixed methods PEDIATRIC Systematic review
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Subtitle Translation Methods of The Good Wife From Functional Equivalence Perspective
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作者 WANG Ya-kun BAO De-wang 《Journal of Literature and Art Studies》 2026年第1期26-30,共5页
The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to... The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to analyze the methods of its English-to-Chinese subtitle translation by considering social,cultural,and historic backgrounds between China and America.After data collection and case analysis,the study found that:(1)Five major translation methods are adopted in the subtitle translation of The Good Wife.They are free translation,variation,literal translation,addition,and omission.Among them,free translation is the most frequently used,while omission is used least.(2)The subtitle translation of films and TV series is limited by time and space restrictions,social-cultural differences,and other factors.When translating,translators should try to use humorous words,euphemism,intonation,and other ways,and combine different methods such as literal translation,free translation,variation,addition,omission,and other methods to seek equivalence both in the meaning and function of subtitles under the guidance of Functional Equivalence Theory. 展开更多
关键词 subtitle translation Functional Equivalence Theory The Good Wife translation methods
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Fourth Order Compact Finite Volume Methods for 1D Elliptic and Parabolic Equations on Non-uniform Meshes
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作者 ZHOU Lei WANG Feng WANG Tongke 《应用数学》 北大核心 2026年第2期342-359,共18页
This paper studies high order compact finite volume methods on non-uniform meshes for one-dimensional elliptic and parabolic differential equations with the Robin boundary conditions.An explicit scheme and an implicit... This paper studies high order compact finite volume methods on non-uniform meshes for one-dimensional elliptic and parabolic differential equations with the Robin boundary conditions.An explicit scheme and an implicit scheme are obtained by discretizing the equivalent integral form of the equation.For the explicit scheme with nodal values,the algebraic system can be solved by the Thomas method.For the implicit scheme with both nodal values and their derivatives,the system can be implemented by a prediction-correction procedure,where in the correction stage,an implicit formula for recovering the nodal derivatives is introduced.Taking two point boundary value problem as an example,we prove that both the explicit and implicit schemes are convergent with fourth order accuracy with respect to some standard discrete norms using the energy method.Two numerical examples demonstrate the correctness and effectiveness of the schemes,as well as the indispensability of using non-uniform meshes. 展开更多
关键词 Two point boundary value problem Parabolic equation Robin boundary condition Non-uniform mesh Fourth order compact finite volume scheme Predictioncorrection method Error estimate
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Analysis of the Effectiveness and Teaching Satisfaction of Diversified Teaching Methods in Clinical Instruction for Operating Room Nursing Interns
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作者 Jie Gao Yuanrong Luo 《Journal of Clinical and Nursing Research》 2026年第2期40-46,共7页
Objective: To analyze the advantages of diversified teaching methods in the clinical instruction of operating room nursing interns. Methods: Twenty-one nursing interns who underwent internships in the operating room f... Objective: To analyze the advantages of diversified teaching methods in the clinical instruction of operating room nursing interns. Methods: Twenty-one nursing interns who underwent internships in the operating room from March 2023 to March 2024 were selected as the control group and received conventional teaching methods. Another twenty-one nursing interns who underwent internships in the operating room from April 2024 to April 2025 were selected as the experimental group and received diversified teaching methods. The teaching effects of the two groups were compared. Results: The experimental group scored higher than the control group in assessments, teaching satisfaction, and teaching quality evaluations, as well as in post-instruction professional identity scores (p < 0.05). Conclusion: Diversified teaching methods can enhance the professional competence of operating room nursing interns, cultivate their professional identity, and yield high teaching satisfaction, thereby improving teaching quality. 展开更多
关键词 Diversified teaching methods Operating room nursing interns Clinical instruction Teaching satisfaction
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Four Major Diseases Affecting Pear Trees and Their Prevention and Control Methods
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作者 Longfei LI Jintao XU +5 位作者 Minghui JI Huan LIU Lijuan GAO Yue YAO Gang NIU Baofeng HAO 《Plant Diseases and Pests》 2026年第1期1-3,13,共4页
This paper presents an overview of the pathogens, symptoms of damage, patterns of occurrence, and chemical control methods associated with four major pear tree diseases: pear scab, pear ring rot, pear anthracnose, and... This paper presents an overview of the pathogens, symptoms of damage, patterns of occurrence, and chemical control methods associated with four major pear tree diseases: pear scab, pear ring rot, pear anthracnose, and pear speckle. The objective is to provide valuable references for the scientific and precise prevention and management of diseases in pear orchards, thereby contributing to the production of high-quality and high-yield pear fruits. 展开更多
关键词 PEAR Disease PATHOGEN Symptoms of damage Patterns of occurrence Prevention and control methods
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Research on multi-fidelity aerodynamic optimization methods 被引量:14
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作者 Huang Likeng Gao Zhenghong Zhang Dehu 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2013年第2期279-286,共8页
Constructing high approximation accuracy surrogate model with lower computational cost has great engineering significance.In this paper,using co-Kriging method,an efficient multi-fidelity surrogate model is constructe... Constructing high approximation accuracy surrogate model with lower computational cost has great engineering significance.In this paper,using co-Kriging method,an efficient multi-fidelity surrogate model is constructed based on two independent high and low fidelity samples.Co-Kriging method can use a greater quantity of low-fidelity information to enhance the accuracy of a surrogate of the high-fidelity model by modeling the correlation between high and low fidelity model,thus computational cost of building surrogate model can be greatly reduced.A wing-body problem is taken as an example to compare characteristics of co-Kriging multi-fidelity(CKMF)model with traditional Kriging based multi-fidelity(KMF)model.A sampling convergence of the CKMF model and the KMF model is conducted,and an appropriate sampling design is selected through the sampling convergence analysis.The results indicate that CKMF model has higher approximation accuracy with the same high-fidelity samples,and converges at less high-fidelity samples.A wing-body drag reduction optimization design using genetic algorithm is implemented.Satisfying design results are obtained,which validate the feasibility of CKMF model in engineering design. 展开更多
关键词 AERODYNAMICS CO-KRIGING multi-fidelity OPTIMIZATION Surrogate model
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Tunnel ahead prospecting methods and intelligent interpretation of adverse geology:A review
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作者 Shucai Li Bin Liu +4 位作者 Lei Chen Huaifeng Sun Lichao Nie Zhengyu Liu Yuxiao Ren 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期1-19,共19页
Geological prospecting and the identification of adverse geological features are essential in tunnel construction,providing critical information to ensure safety and guide engineering decisions.As tunnel projects exte... Geological prospecting and the identification of adverse geological features are essential in tunnel construction,providing critical information to ensure safety and guide engineering decisions.As tunnel projects extend into deeper and more mountainous terrains,engineers face increasingly complex geological conditions,including high water pressure,intense geo-stress,elevated geothermal gradients,and active fault zones.These conditions pose substantial risks such as high-pressure water inrush,largescale collapses,and tunnel boring machine(TBM)blockages.Addressing these challenges requires advanced detection technologies capable of long-distance,high-precision,and intelligent assessments of adverse geology.This paper presents a comprehensive review of recent advancements in tunnel geological ahead prospecting methods.It summarizes the fundamental principles,technical maturity,key challenges,development trends,and real-world applications of various detection techniques.Airborne and semi-airborne geophysical methods enable large-scale reconnaissance for initial surveys in complex terrain.Tunnel-and borehole-based approaches offer high-resolution detection during excavation,including seismic ahead prospecting(SAP),TBM rock-breaking source seismic methods,fulltime-domain tunnel induced polarization(TIP),borehole electrical resistivity,and ground penetrating radar(GPR).To address scenarios involving multiple,coexisting adverse geologies,intelligent inversion and geological identification methods have been developed based on multi-source data fusion and artificial intelligence(AI)techniques.Overall,these advances significantly improve detection range,resolution,and geological characterization capabilities.The methods demonstrate strong adaptability to complex environments and provide reliable subsurface information,supporting safer and more efficient tunnel construction. 展开更多
关键词 Tunnel geological ahead prospecting Complex geological and environmental conditions Airborne geophysical methods Tunnel geophysical detection Borehole geophysical prospecting Intelligent geological interpretation
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Structural Modal Parameter Recognition and Related Damage Identification Methods under Environmental Excitations:A Review 被引量:7
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作者 Chao Zhang Shang-Xi Lai Hua-Ping Wang 《Structural Durability & Health Monitoring》 EI 2025年第1期25-54,共30页
Modal parameters can accurately characterize the structural dynamic properties and assess the physical state of the structure.Therefore,it is particularly significant to identify the structural modal parameters accordi... Modal parameters can accurately characterize the structural dynamic properties and assess the physical state of the structure.Therefore,it is particularly significant to identify the structural modal parameters according to the monitoring data information in the structural health monitoring(SHM)system,so as to provide a scientific basis for structural damage identification and dynamic model modification.In view of this,this paper reviews methods for identifying structural modal parameters under environmental excitation and briefly describes how to identify structural damages based on the derived modal parameters.The paper primarily introduces data-driven modal parameter recognition methods(e.g.,time-domain,frequency-domain,and time-frequency-domain methods,etc.),briefly describes damage identification methods based on the variations of modal parameters(e.g.,natural frequency,modal shapes,and curvature modal shapes,etc.)and modal validation methods(e.g.,Stability Diagram and Modal Assurance Criterion,etc.).The current status of the application of artificial intelligence(AI)methods in the direction of modal parameter recognition and damage identification is further discussed.Based on the pre-vious analysis,the main development trends of structural modal parameter recognition and damage identification methods are given to provide scientific references for the optimized design and functional upgrading of SHM systems. 展开更多
关键词 Structural health monitoring data information modal parameters damage identification AI method
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A multi-fidelity simulation method research on front variable area bypass injector of an adaptive cycle engine 被引量:12
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作者 Zhewen XU Ming LI +1 位作者 Hailong TANG Min CHEN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第4期202-219,共18页
Front Variable Area Bypass Injector(Front-VABI) is a component of the Adaptive Cycle Engine(ACE) with important variable-cycle features. The performance of Front-VABI has a direct impact on the performance and stabili... Front Variable Area Bypass Injector(Front-VABI) is a component of the Adaptive Cycle Engine(ACE) with important variable-cycle features. The performance of Front-VABI has a direct impact on the performance and stability of ACE, but the current ACE performance model uses approximate models for Front-VABI performance calculation. In this work, a multi-fidelity simulation based on a de-coupled method is developed which delivers a more accurate calculation of the Front-VABI performance based on Computational Fluid Dynamics(CFD) simulation. This simulation method proposes a form of Front-VABI characteristic and its matching calculation method between it and the ACE performance model, constructs a coupling method between the(2-D) Front-VABI model and the(0-D) ACE performance model. The result shows, when ACE works in triple bypass mode, the approximate model cannot account for the effect of FrontVABI pressure loss on Core Driven Fan Stage(CDFS) design pressure ratio, and the calculated error of high-pressure turbine inlet total temperature is more than 40 K in mode transition condition(the transition operating condition between triple bypass mode and double bypass mode). In double bypass mode, the approximate model can better simulate the performance of FrontVABI by considering the local loss of area expansion. This method can be applied to the performance-optimized design of Front-VABI and the ACE control law design during mode transition. 展开更多
关键词 Adaptive cycle engine Computational fluid dynamics Front variable area bypass injector multi-fidelity simulation Performance model
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Data-Model Fusion Methods and Applications Toward Smart Manufacturing and Digital Engineering 被引量:1
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作者 Fei Tao Yilin Li +2 位作者 Yupeng Wei Chenyuan Zhang Ying Zuo 《Engineering》 2025年第12期36-50,共15页
As pivotal supporting technologies for smart manufacturing and digital engineering,model-based and data-driven methods have been widely applied in many industrial fields,such as product design,process monitoring,and s... As pivotal supporting technologies for smart manufacturing and digital engineering,model-based and data-driven methods have been widely applied in many industrial fields,such as product design,process monitoring,and smart maintenance.While promising,both methods have issues that need to be addressed.For example,model-based methods are limited by low computational accuracy and a high computational burden,and data-driven methods always suffer from poor interpretability and redundant features.To address these issues,the concept of data-model fusion(DMF)emerges as a promising solution.DMF involves integrating model-based methods with data-driven methods by incorporating big data into model-based methods or embedding relevant domain knowledge into data-driven methods.Despite growing efforts in the field of DMF,a unanimous definition of DMF remains elusive,and a general framework of DMF has been rarely discussed.This paper aims to address this gap by providing a thorough overview and categorization of both data-driven methods and model-based methods.Subsequently,this paper also presents the definition and categorization of DMF and discusses the general framework of DMF.Moreover,the primary seven applications of DMF are reviewed within the context of smart manufacturing and digital engineering.Finally,this paper directs the future directions of DMF. 展开更多
关键词 Data-model fusion Model-based methods Data-driven methods Smart manufacturing Digital engineering
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Improved methods,properties,applications and prospects of microbial induced carbonate precipitation(MICP)treated soil:A review 被引量:3
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作者 Xuanshuo Zhang Hongyu Wang +3 位作者 Ya Wang Jinghui Wang Jing Cao Gang Zhang 《Biogeotechnics》 2025年第1期34-54,共21页
Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vi... Soil improvement is one of the most important issues in geotechnical engineering practice.The wide application of traditional improvement techniques(cement/chemical materials)are limited due to damage ecological en-vironment and intensify carbon emissions.However,the use of microbially induced calcium carbonate pre-cipitation(MICP)to obtain bio-cement is a novel technique with the potential to induce soil stability,providing a low-carbon,environment-friendly,and sustainable integrated solution for some geotechnical engineering pro-blems in the environment.This paper presents a comprehensive review of the latest progress in soil improvement based on the MICP strategy.It systematically summarizes and overviews the mineralization mechanism,influ-encing factors,improved methods,engineering characteristics,and current field application status of the MICP.Additionally,it also explores the limitations and correspondingly proposes prospective applications via the MICP approach for soil improvement.This review indicates that the utilization of different environmental calcium-based wastes in MICP and combination of materials and MICP are conducive to meeting engineering and market demand.Furthermore,we recommend and encourage global collaborative study and practice with a view to commercializing MICP technique in the future.The current review purports to provide insights for engineers and interdisciplinary researchers,and guidance for future engineering applications. 展开更多
关键词 Soil improvement Bio-cement MICP Improved methods Field application cases
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Insight Into the Separation-of-Variable Methods for the Closed-Form Solutions of Free Vibration of Rectangular Thin Plates
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作者 Yufeng Xing Ye Yuan Gen Li 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期329-355,共27页
The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytica... The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical shells.By taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue equations.Besides,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are investigated.It is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well. 展开更多
关键词 Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method
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A review of research methods for elucidating the microstructure of pharmaceutical preparations 被引量:1
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作者 Peng Yan Zhiyuan Hou Jinsong Ding 《Journal of Pharmaceutical Analysis》 2025年第5期901-915,共15页
The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and e... The microstructures of pharmaceutical preparations play a pivotal role in determining their critical quality attributes(CQAs),such as drug release,content uniformity,and stability,which greatly impact the safety and efficacy of drugs.Unlike the inherent molecular structures of active pharmaceutical ingredients(APIs)and excipients,the microstructures of pharmaceutical preparations are developed during the formulation process,presenting unique analytical challenges.In this review,we primarily focus on presenting the research methods used to elucidate the microstructures of pharmaceutical preparations,including X-ray imaging(XRI),scanning electron microscopy(SEM),atomic force microscopy(AFM),Raman spectroscopy,infrared(IR)spectroscopy,and rheometer technology.Subsequently,we highlight the applications,advantages,and limitations of these methods.Finally,we discuss the current challenges and future perspectives in this field.This review aims to provide a comprehensive reference for understanding the microstructures of pharmaceutical preparations,offering new insights and potential advancements in their development. 展开更多
关键词 MICROSTRUCTURE Pharmaceutical preparation Critical quality attributes Research methods
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A review of current studies on the unmanned aerial vehicle-based moving target tracking methods 被引量:3
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作者 Binbin Yan Yuxin Wei +3 位作者 Shuangxi Liu Wei Huang Ruizhe Feng Xiaoqian Chen 《Defence Technology(防务技术)》 2025年第9期201-219,共19页
Unmanned aerial vehicles(UAVs)have become crucial tools in moving target tracking due to their agility and ability to operate in complex,dynamic environments.UAVs must meet several requirements to achieve stable track... Unmanned aerial vehicles(UAVs)have become crucial tools in moving target tracking due to their agility and ability to operate in complex,dynamic environments.UAVs must meet several requirements to achieve stable tracking,including maintaining continuous target visibility amidst occlusions,ensuring flight safety,and achieving smooth trajectory planning.This paper reviews the latest advancements in UAV-based target tracking,highlighting information prediction,tracking strategies,and swarm cooperation.To address challenges including target visibility and occlusion,real-time prediction and tracking in dynamic environments,flight safety and coordination,resource management and energy efficiency,the paper identifies future research directions aimed at improving the performance,reliability,and scalability of UAV tracking system. 展开更多
关键词 Unmanned aerial vehicle(UAV) Tracking methods Moving targets Information prediction Tracking strategies Swarm cooperation
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Review on internal flow mechanism and control methods of axial flow compressor at low Reynolds number 被引量:1
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作者 Xuyang REN Xingen LU +6 位作者 Mingyang WANG Ge HAN Chengwu YANG Xu DONG Lipan YAO Yanfeng ZHANG Shengfeng ZHAO 《Chinese Journal of Aeronautics》 2025年第5期7-27,共21页
With the continuous increase of aeroengine flight ceiling(>20 km),the thin atmosphere at high altitudes and the size effect all cause the compressor component inlet Reynolds number to decrease rapidly to a critical... With the continuous increase of aeroengine flight ceiling(>20 km),the thin atmosphere at high altitudes and the size effect all cause the compressor component inlet Reynolds number to decrease rapidly to a critical value(approximately 2.0×10^(5)),and the significant transition process on the blade/endwall surface leads to the sharp degradation of compressor performance,which seriously affects the engine fuel consumption and working stability at high altitudes.In this paper,the research progress on the internal flow mechanism and flow control methods of axial compressors at low Reynolds numbers is reviewed from the aspects of quantification and prediction of performance variation,flow loss mechanism related to separation and transition,efficient transition control and flow field organization.The development trend of the low-Reynolds-number effect of axial flow compressors is noted,and the difficulties and application prospects of aerodynamic design and efficient flow control methods for compressors under low Reynolds numbers at high altitudes are discussed. 展开更多
关键词 LowReynolds number Axial compressor Flow mechanism Flow control methods AEROENGINE
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A novel multi-fidelity coupled simulation method for flow systems 被引量:1
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作者 Wang Peng Zheng Yun +2 位作者 Zou Zhengping Qi Lei Zhou Zhixiang 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2013年第4期868-875,共8页
For the numerical simulation of flow systems with various complex components, the traditional one-dimensional (1D) network method has its comparative advantage in time consuming and the CFD method has its absolute a... For the numerical simulation of flow systems with various complex components, the traditional one-dimensional (1D) network method has its comparative advantage in time consuming and the CFD method has its absolute advantage in the detailed flow capturing. The proper coupling of the advantages of different dimensional methods can strike balance well between time cost and accuracy and then significantly decrease the whole design cycle for the flow systems in modern machines. A novel multi-fidelity coupled simulation method with numerical zooming is developed for flow systems. This method focuses on the integration of one-, two-and three-dimensional codes for various components. Coupled iterative process for the different dimensional simulation cycles of sub-systems is performed until the concerned flow variables of the whole system achieve convergence. Numerical zooming is employed to update boundary data of components with different dimen-sionalities. Based on this method, a highly automatic, multi-discipline computing environment with integrated zooming is developed. The numerical results of Y-Junction and the air system of a jet engine are presented to verify the solution method. They indicate that this type of multi-fidelity simulationmethod can greatly improve the prediction capability for the flow systems. 展开更多
关键词 Complex flow system Coupling Jet engine multi-fidelity Zooming
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Numerical Methods for Boundary Value Problems in Variable Coefficient Ordinary Differential Equations 被引量:1
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作者 ZHAO Ting-ting CAI Wei-yun 《Chinese Quarterly Journal of Mathematics》 2025年第3期295-303,共9页
In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error... In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error between the numerical solution and the exact solution is obtained,and then compared with the error formed by the difference method,it is concluded that the Lagrange interpolation method is more effective in solving the variable coefficient ordinary differential equation. 展开更多
关键词 Variable coefficient ordinary differential equations Lagrange interpolation Difference methods
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