Dear Editor,Hypoxic microenvironment is clinically associated with metastasis and poor prognosis of numerous cancers.Previous studies have shown that many protein-coding genes and microRNAs are regulated upon hypoxia ...Dear Editor,Hypoxic microenvironment is clinically associated with metastasis and poor prognosis of numerous cancers.Previous studies have shown that many protein-coding genes and microRNAs are regulated upon hypoxia and involved in the progression of cancer.However,the roles of lncRNAs in the hypoxia-responsive gene networks and how lncRNA-related signaling network regulates hypoxia induced tumor metastasis is still not clear.展开更多
基金supported by the National Natural Science Foundation of China(81672376,81972714,and 81602102)the State Key Project on Infection Diseases of China(2018ZX10723204)+2 种基金Joint Funds of Fujian Provincial Health and Education Research(2019-WJ-19)the Startup Fund for scientific research,Fujian Medical University(2018QH1201,2018QH1199)the Scientific Foundation of Fujian Province(2019D003).
文摘Dear Editor,Hypoxic microenvironment is clinically associated with metastasis and poor prognosis of numerous cancers.Previous studies have shown that many protein-coding genes and microRNAs are regulated upon hypoxia and involved in the progression of cancer.However,the roles of lncRNAs in the hypoxia-responsive gene networks and how lncRNA-related signaling network regulates hypoxia induced tumor metastasis is still not clear.
