Mathematical models in seismo-geochemical monitoring offer powerful tools for the study and exploration of complex dynamics associated with discharge of radon as the indicator of change of intense-deformed conditions ...Mathematical models in seismo-geochemical monitoring offer powerful tools for the study and exploration of complex dynamics associated with discharge of radon as the indicator of change of intense-deformed conditions of seismogenic layers or blocks within the lithosphere. Seismic precursory model of radon gas emanation in the process of earthquake prediction research aims to find out the distinct anomaly variation necessary to correlate radon gas with processes of preparation and realization of tectonic earthquakes in long-term and short-term forecasts tectonic earthquakes. The study involves a radon gas volume analytic model to find the correlation of radon fluctuations to stress drop under compression and dilatation strain condition. Here, we present a mathematical inference by observing radon gas emanation prior to the occurrence of earthquake that may reduce the uncertainties in models and updating their probability distributions in a Bayesian deterministic model. Using Bayesian melding theorem, we implement an inferential framework to understand the process of preparation of tectonic earthquake and concurrent occurrence of radon discharge during a tectonic earthquake phenomena. Bayesian melding for deterministic simulation models was augmented to make use of prior knowledge on correlations between model inputs. The background porosity is used as a priori information for analyzing the block subjected to inelastic strain. It can be inferred that use of probabilistic framework involving exhalation of radon may provide a scenario of earthquake occurrences on recession of the curve that represents a qualitative pattern of radon activity concentration drop, indicating associated stress change within the causative seismogenic fault. Using evidence analysis, we propose a joint conditional probability framework model simulation to understand how a single fracture may be affected in response to an external load and radon anomaly change that can be used to detect the slip, a predictable nature of the causative fault in the subsurface rock.展开更多
目的:探讨肝移植患者终末期肝病模型(MELD)与术后营养状态的关系,以期为临床提供更精确的评估工具和管理策略。方法:收集2019年1月至2023年7月于本中心接受肝移植术的99例患者的临床资料,使用腰大肌身高指数对患者术后生存及营养状态进...目的:探讨肝移植患者终末期肝病模型(MELD)与术后营养状态的关系,以期为临床提供更精确的评估工具和管理策略。方法:收集2019年1月至2023年7月于本中心接受肝移植术的99例患者的临床资料,使用腰大肌身高指数对患者术后生存及营养状态进行预测;依据病因、MELD评分进行亚组分析。结果:少肌症组和无少肌症组在年龄、白蛋白水平、L3-PMI以及生存时间上有统计学意义(p 3-PMI为A组3.51 ± 0.75、B组2.47 ± 0.76、C组2.76 ± 0.96,酒精性肝硬化患者L3-PMI为A组3.13 ± 0.45、B组2.25 ± 0.28、C组3.01 ± 1.92,A与B组之间比较差异有统计学意义(p 3-PMI为A组3.74 ± 0.83、B组2.88 ± 0.53、C组2.09 ± 0.36,三组组间比较均有统计学意义(p 3-PMI可以有效评价患者营养状况和术后生存状态;MELD评分与术后营养状况存在显著的相关性,高MELD评分的患者往往术后营养状况较低,容易发生营养障碍。Objective: To explore the relationship between end-stage liver disease (MELD) model and postoperative nutritional status in liver transplant patients, in order to provide more accurate assessment tools and management strategies for clinical practice. Method: Clinical data of 99 patients who underwent liver transplantation at our center from January 2019 to July 2023 were collected, and the lumbar muscle height index was used to predict the postoperative survival and nutritional status of the patients;Perform subgroup analysis based on etiology and MELD score. Result: There were statistically significant differences (p 3-PMI, and survival time between the sarcopenia group and the non sarcopenia group. In the MELD scoring subgroups, the L3-PMI of patients with liver malignant tumors was 3.51 ± 0.75 in group A, 2.47 ± 0.76 in group B, and 2.76 ± 0.96 in group C. The L3-PMI of patients with alcoholic cirrhosis was 3.13 ± 0.45 in group A, 2.25 ± 0.28 in group B, and 3.01 ± 1.92 in group C. There was a statistically significant difference between group A and group B (p 3-PMI of decompensated patients with hepatitis B cirrhosis was 3.74 ± 0.83 in group A, 2.88 ± 0.53 in group B, and 2.09 ± 0.36 in group C. The comparison among the three groups was statistically significant (p 3-PMI can effectively evaluate the nutritional status and postoperative survival status of patients;There is a significant correlation between MELD score and postoperative nutritional status. Patients with high MELD scores often have lower postoperative nutritional status and are prone to nutritional disorders.展开更多
文摘Mathematical models in seismo-geochemical monitoring offer powerful tools for the study and exploration of complex dynamics associated with discharge of radon as the indicator of change of intense-deformed conditions of seismogenic layers or blocks within the lithosphere. Seismic precursory model of radon gas emanation in the process of earthquake prediction research aims to find out the distinct anomaly variation necessary to correlate radon gas with processes of preparation and realization of tectonic earthquakes in long-term and short-term forecasts tectonic earthquakes. The study involves a radon gas volume analytic model to find the correlation of radon fluctuations to stress drop under compression and dilatation strain condition. Here, we present a mathematical inference by observing radon gas emanation prior to the occurrence of earthquake that may reduce the uncertainties in models and updating their probability distributions in a Bayesian deterministic model. Using Bayesian melding theorem, we implement an inferential framework to understand the process of preparation of tectonic earthquake and concurrent occurrence of radon discharge during a tectonic earthquake phenomena. Bayesian melding for deterministic simulation models was augmented to make use of prior knowledge on correlations between model inputs. The background porosity is used as a priori information for analyzing the block subjected to inelastic strain. It can be inferred that use of probabilistic framework involving exhalation of radon may provide a scenario of earthquake occurrences on recession of the curve that represents a qualitative pattern of radon activity concentration drop, indicating associated stress change within the causative seismogenic fault. Using evidence analysis, we propose a joint conditional probability framework model simulation to understand how a single fracture may be affected in response to an external load and radon anomaly change that can be used to detect the slip, a predictable nature of the causative fault in the subsurface rock.
文摘目的:探讨肝移植患者终末期肝病模型(MELD)与术后营养状态的关系,以期为临床提供更精确的评估工具和管理策略。方法:收集2019年1月至2023年7月于本中心接受肝移植术的99例患者的临床资料,使用腰大肌身高指数对患者术后生存及营养状态进行预测;依据病因、MELD评分进行亚组分析。结果:少肌症组和无少肌症组在年龄、白蛋白水平、L3-PMI以及生存时间上有统计学意义(p 3-PMI为A组3.51 ± 0.75、B组2.47 ± 0.76、C组2.76 ± 0.96,酒精性肝硬化患者L3-PMI为A组3.13 ± 0.45、B组2.25 ± 0.28、C组3.01 ± 1.92,A与B组之间比较差异有统计学意义(p 3-PMI为A组3.74 ± 0.83、B组2.88 ± 0.53、C组2.09 ± 0.36,三组组间比较均有统计学意义(p 3-PMI可以有效评价患者营养状况和术后生存状态;MELD评分与术后营养状况存在显著的相关性,高MELD评分的患者往往术后营养状况较低,容易发生营养障碍。Objective: To explore the relationship between end-stage liver disease (MELD) model and postoperative nutritional status in liver transplant patients, in order to provide more accurate assessment tools and management strategies for clinical practice. Method: Clinical data of 99 patients who underwent liver transplantation at our center from January 2019 to July 2023 were collected, and the lumbar muscle height index was used to predict the postoperative survival and nutritional status of the patients;Perform subgroup analysis based on etiology and MELD score. Result: There were statistically significant differences (p 3-PMI, and survival time between the sarcopenia group and the non sarcopenia group. In the MELD scoring subgroups, the L3-PMI of patients with liver malignant tumors was 3.51 ± 0.75 in group A, 2.47 ± 0.76 in group B, and 2.76 ± 0.96 in group C. The L3-PMI of patients with alcoholic cirrhosis was 3.13 ± 0.45 in group A, 2.25 ± 0.28 in group B, and 3.01 ± 1.92 in group C. There was a statistically significant difference between group A and group B (p 3-PMI of decompensated patients with hepatitis B cirrhosis was 3.74 ± 0.83 in group A, 2.88 ± 0.53 in group B, and 2.09 ± 0.36 in group C. The comparison among the three groups was statistically significant (p 3-PMI can effectively evaluate the nutritional status and postoperative survival status of patients;There is a significant correlation between MELD score and postoperative nutritional status. Patients with high MELD scores often have lower postoperative nutritional status and are prone to nutritional disorders.
