This paper deals with the studies on the changes of serum specific IgM andIgG,and relationship between the antibody level and infected worm stage of Brugiamalayi.The jirds (Meriones unguiculatus)and BALB/cCR mice were...This paper deals with the studies on the changes of serum specific IgM andIgG,and relationship between the antibody level and infected worm stage of Brugiamalayi.The jirds (Meriones unguiculatus)and BALB/cCR mice were infected with threedifferent stages of Brugia malayi by different routes and serum specific IgM and IgGwere detected by ELISA mcthod.The IgM of infected jirds and mice occurred earlierthan IgG,reached peak at 4～8th weeks,and maintained at a certain level during 30weeks.The responses and toles of IgM and IgG might probably be considered as animmunological characferistic of parasitic helminthic infection.The antibody levels inBALB/cCR mice after infection were higher than those in jirds.展开更多
剖腹后,将多栖培养的溶组织内阿米巴滋养体接种到长爪沙鼠盲肠内。接种后7～20 d 检查受试动物的肠内容物及肠、肝、脾、肠系膜淋巴结的病理组织学变化。16只受试动物有12只受染,其中7只出现盲肠病变,主要表现为粘膜表面縻烂,肠壁各层...剖腹后,将多栖培养的溶组织内阿米巴滋养体接种到长爪沙鼠盲肠内。接种后7～20 d 检查受试动物的肠内容物及肠、肝、脾、肠系膜淋巴结的病理组织学变化。16只受试动物有12只受染,其中7只出现盲肠病变,主要表现为粘膜表面縻烂,肠壁各层均有巨噬细胞和淋巴细胞浸润。其中1鼠的肠系膜淋巴结出现小灶状坏死,肝脏出现多发性小阿米巴脓肿。展开更多
文摘This paper deals with the studies on the changes of serum specific IgM andIgG,and relationship between the antibody level and infected worm stage of Brugiamalayi.The jirds (Meriones unguiculatus)and BALB/cCR mice were infected with threedifferent stages of Brugia malayi by different routes and serum specific IgM and IgGwere detected by ELISA mcthod.The IgM of infected jirds and mice occurred earlierthan IgG,reached peak at 4～8th weeks,and maintained at a certain level during 30weeks.The responses and toles of IgM and IgG might probably be considered as animmunological characferistic of parasitic helminthic infection.The antibody levels inBALB/cCR mice after infection were higher than those in jirds.
文摘剖腹后,将多栖培养的溶组织内阿米巴滋养体接种到长爪沙鼠盲肠内。接种后7～20 d 检查受试动物的肠内容物及肠、肝、脾、肠系膜淋巴结的病理组织学变化。16只受试动物有12只受染,其中7只出现盲肠病变,主要表现为粘膜表面縻烂,肠壁各层均有巨噬细胞和淋巴细胞浸润。其中1鼠的肠系膜淋巴结出现小灶状坏死,肝脏出现多发性小阿米巴脓肿。
