1 EXTREME DROUGHT AND HYDROGEODESY TECHNOLOGIES The World Meteorological Organization has officially declared 2023 as the hottest year on record,with the average global temperature surpassing pre-industrial(1850-1900)...1 EXTREME DROUGHT AND HYDROGEODESY TECHNOLOGIES The World Meteorological Organization has officially declared 2023 as the hottest year on record,with the average global temperature surpassing pre-industrial(1850-1900)average by 1.45℃.While temperature is not the only climate observable from the complex processes for the geneses of droughts,recent hottest years have witnessed numerous instances of extreme droughts.展开更多
Background: Wrist pain is prevalent. Activities such as dexterous sports, prolonged use of personal handheld devices, and extensive desktop keyboard usage are common contributors to wrist pain. Intersection syndrome, ...Background: Wrist pain is prevalent. Activities such as dexterous sports, prolonged use of personal handheld devices, and extensive desktop keyboard usage are common contributors to wrist pain. Intersection syndrome, a form of inflammatory tenosynovitis, occurs at the intersection of the first and second dorsal compartments of the wrist. The first dorsal compartment is comprised of the tendons of abductor pollicis longus and extensor pollicis brevis, while the second dorsal compartment contains the tendons of extensor carpi radialis longus and extensor carpi radialis brevis. Intersection syndrome is diagnosed by pain localized to the dorsoradial forearm, approximately five cm proximal to the wrist joint, which worsens with resisted wrist and thumb extension. To date, the use of hydro dissection with 5% dextrose under ultrasound guidance as a treatment for Intersection syndrome has not been reported. This case report presents the first report on ultrasound-guided hydro dissection as a therapeutic approach for intersection syndrome. Methods: A case report, with informed consent, involving a 32-year-old male athlete. The patient, a hurling player, presented with chronic right wrist pain diagnosed as intersection syndrome. The condition significantly affected his work, sporting activities, and daily living activities. Previous conservative management and physiotherapy had failed to alleviate his symptoms. To confirm the diagnosis, relevant imaging was performed, supplemented by dynamic ultrasound assessment. The procedure was performed aseptically. Continuous ultrasound guidance was employed to ensure accurate needle placement. Once the needle tip position was confirmed, an initial injection of 5 mL of 0.25% chirocaine was administered. 10 mL of 5% dextrose was injected under ultrasound guidance for hydro dissection, with good visualization of the solution’s distribution. Conclusion: Ultrasound-guided hydro dissection has not previously been documented as a treatment option for intersection syndrome. In this case, it proved to be an effective pain-relieving therapy with sustained effect at three-month clinical follow-up. Further studies are required.展开更多
The first total synthesis of marine sesquiterpene(hydro)quinone meroterpenoids dysideanones A and E–G(1 and 4–6)has been accomplished in an enantioselective and divergent way.The sesquiterpene fragment and the aroma...The first total synthesis of marine sesquiterpene(hydro)quinone meroterpenoids dysideanones A and E–G(1 and 4–6)has been accomplished in an enantioselective and divergent way.The sesquiterpene fragment and the aromatic moiety were efficiently connected via a site-selective and diastereoselective intermolecular alkylation of Wieland–Miescher ketone derivative 9 and benzyl bromide 10.The core 6/6/6/6-fused backbone of dysideanones was efficiently constructed through an intramolecular radical cyclization reaction.Dysideanone G(6)was easily prepared on a gram-scale and dysideanones A,E,and F(1,4,and 5)were divergently transformed from dysideanone G(6)in one or two steps.展开更多
在人类活动加重气候变暖的背景下,极端水文气象事件发生概率增加。数值模式作为研究水循环和极端水文事件的有效工具,已在全球范围内得到广泛应用。为深入理解气候变化背景下全球陆地水循环时空演变规律,揭示大气-陆面-水文互馈机制,大...在人类活动加重气候变暖的背景下,极端水文气象事件发生概率增加。数值模式作为研究水循环和极端水文事件的有效工具,已在全球范围内得到广泛应用。为深入理解气候变化背景下全球陆地水循环时空演变规律,揭示大气-陆面-水文互馈机制,大气-陆面-水文耦合过程模拟研究已成为国际大气、水文等学科研究的热点之一。本文首先回顾和梳理了大气-陆面-水文耦合模式的发展历程,阐明了大气-陆面-水文耦合模式WRF-Hydro(Weather Research and Forecasting Model Hydrological modeling system)的优势,并系统总结了WRF-Hydro模式的主要敏感性参数分析及模式在对地表径流、土壤湿度、能量水分循环以及相关大气和水文过程等方面的应用。最后探讨WRF-Hydro大气-陆面-水文耦合模式未来发展趋势,提出应着眼于发展有效的尺度转换方案、完善参数化方案以及开展流域内大气、水文变量时空分布高分辨率模拟等方面,以期系统提升耦合模式对大气、陆面过程及水文过程的刻画能力。展开更多
黄河源区是黄河流域主要的产流区和水源涵养区,研究和探索该区域陆面水文过程对理解陆面过程及水文循环特征,揭示陆面—水文耦合过程具有重要的科学意义。本研究基于2009~2018年中国区域高时空分辨率地面气象要素驱动数据(China Meteoro...黄河源区是黄河流域主要的产流区和水源涵养区,研究和探索该区域陆面水文过程对理解陆面过程及水文循环特征,揭示陆面—水文耦合过程具有重要的科学意义。本研究基于2009~2018年中国区域高时空分辨率地面气象要素驱动数据(China Meteorological Forcing Dataset,简称CMFD)、全球高分辨率降水数据集(Climate Prediction Center Morphing Technique,简称CMORPH)、热带降雨测量卫星(Tropical Rainfall Measuring Mission,简称TRMM)及全球陆地数据同化系统(Global Land Data Assimilation System,简称GLDAS)降水,评估了四类降水产品在黄河源区的降水精度,在此基础上,利用最优降水数据驱动独立运行的天气研究预报及水文耦合模型系统(Weather Research and Forecasting Model Hydrological modeling system,简称WRF-Hydro),探究该模式在黄河源区径流模拟的适用性。结果表明:四类降水产品均能够反映出降水的分布特征,但在量值及细节捕捉上存在显著差异。CMFD在不同时空尺度上都能很好地捕捉到降水的演变特征,其与日观测降水的相关系数达到0.99,均方根误差仅为0.25 mm。在表征降水能力方面,四类降水产品总体表现为CMFD>CMORPH>TRMM>GLDAS,CMFD的平均探测成功率(Critical Success Index,简称CSI)在0.93以上。经参数率定后的WRF-Hydro模式在黄河源区月径流模拟方面表现较好,率定期纳什系数(Nash-Sutcliffe efficiency coefficient,简称NSE)均在0.92以上,而验证期丰水年模拟结果明显好于枯水年(NSE=0.15),这与降水和径流的非线性程度有关。本研究方案和结果为亚寒带半干旱气候区大尺度流域水文模拟及径流预测提供了一定的参考价值。展开更多
The article discusses engineering approaches to solving the problem of oil vapours in generators. Due to the design characteristics of each power plant, it is difficult to find a typical solution. Nevertheless, the ar...The article discusses engineering approaches to solving the problem of oil vapours in generators. Due to the design characteristics of each power plant, it is difficult to find a typical solution. Nevertheless, the article suggests ways to reduce the amount of oil mist. For their implementation, a calculation methodology based on the substitution scheme of the hydraulic path of the bearing support unit is created which takes into account the design features of the bearing and the parameters of the environment around the oil bath. The methodology employed is presented. The numerical method of modelling the aerodynamic fields of the entire hydro generator is used to estimate the air flows and pressures in the oil bath zone of the thrust bearing. Additionally, the method made it possible to track suspected oil particles that could get from the thrust-bearing bath into the surrounding area of the generator. Measures are proposed to reduce the level of oil mist through the competent design of the oil vapour removal system from the bearing bath.展开更多
Poor design of ground water evacuation mechanisms is often blocked and leads to the rise of ground water behind the wall. As a result, free water behind the wall that is not quickly evacuated, increases the lateral pr...Poor design of ground water evacuation mechanisms is often blocked and leads to the rise of ground water behind the wall. As a result, free water behind the wall that is not quickly evacuated, increases the lateral pressure and thus favors overturning failure. The resolution of the overturning problem in cantilever retaining walls caused by hydro-mechanical interaction was studied. An analytical and numerical method was used to study this type of wall-floor interaction. Then Coulomb’s design criterion against overturning to develop a mathematical model that compute analytical factor of safety against overturning in different water conditions and heel lengths was used. The modeling and simulation of this system in the Cast3m software which took into account a wide variety of floor and wall properties were performed. The numerical factor of safety against rollover was obtained, and the graphs for the factor of safety versus heel length and immersion depth for both methods were plotted. From (0 ≤ Hw ≤ H/3), water effect is not dangerous to wall stability against overturning and from (H/3 Hw ≤ H), water effect is very dangerous to wall stability against overturning. For analytical and numerical methods, the heel can be predimensioned against overturning as: Lc: [0.27H 0.38H], [0.29H 0.43H] for 0 ≤Hw ≤ H/3;[0.33H 0.45H], [0.39H 0.53H] for H/3 Hw ≤ 2H/3;[0.5H 0.6H], [0.50H 0.67H] for 2H/3 Hw≤ H. The numerical method guaranteeing more safety than the analytical method, Cantilever retaining walls can thus be pre-dimensioned considering Clayey-Sand soil in hydro-mechanical conditions.展开更多
基金funded by the National Natural Science Fund of China(Nos.42442015,42274111)。
文摘1 EXTREME DROUGHT AND HYDROGEODESY TECHNOLOGIES The World Meteorological Organization has officially declared 2023 as the hottest year on record,with the average global temperature surpassing pre-industrial(1850-1900)average by 1.45℃.While temperature is not the only climate observable from the complex processes for the geneses of droughts,recent hottest years have witnessed numerous instances of extreme droughts.
文摘Background: Wrist pain is prevalent. Activities such as dexterous sports, prolonged use of personal handheld devices, and extensive desktop keyboard usage are common contributors to wrist pain. Intersection syndrome, a form of inflammatory tenosynovitis, occurs at the intersection of the first and second dorsal compartments of the wrist. The first dorsal compartment is comprised of the tendons of abductor pollicis longus and extensor pollicis brevis, while the second dorsal compartment contains the tendons of extensor carpi radialis longus and extensor carpi radialis brevis. Intersection syndrome is diagnosed by pain localized to the dorsoradial forearm, approximately five cm proximal to the wrist joint, which worsens with resisted wrist and thumb extension. To date, the use of hydro dissection with 5% dextrose under ultrasound guidance as a treatment for Intersection syndrome has not been reported. This case report presents the first report on ultrasound-guided hydro dissection as a therapeutic approach for intersection syndrome. Methods: A case report, with informed consent, involving a 32-year-old male athlete. The patient, a hurling player, presented with chronic right wrist pain diagnosed as intersection syndrome. The condition significantly affected his work, sporting activities, and daily living activities. Previous conservative management and physiotherapy had failed to alleviate his symptoms. To confirm the diagnosis, relevant imaging was performed, supplemented by dynamic ultrasound assessment. The procedure was performed aseptically. Continuous ultrasound guidance was employed to ensure accurate needle placement. Once the needle tip position was confirmed, an initial injection of 5 mL of 0.25% chirocaine was administered. 10 mL of 5% dextrose was injected under ultrasound guidance for hydro dissection, with good visualization of the solution’s distribution. Conclusion: Ultrasound-guided hydro dissection has not previously been documented as a treatment option for intersection syndrome. In this case, it proved to be an effective pain-relieving therapy with sustained effect at three-month clinical follow-up. Further studies are required.
基金Financial support for this work was provided by the National Natural Science Foundation of China(Nos.22171146,21971121,and 22188101)the Fundamental Research Funds for the Central Universities,Nankai University(No.63231199)the State Key Laboratory of Medicinal Chemical Biology。
文摘The first total synthesis of marine sesquiterpene(hydro)quinone meroterpenoids dysideanones A and E–G(1 and 4–6)has been accomplished in an enantioselective and divergent way.The sesquiterpene fragment and the aromatic moiety were efficiently connected via a site-selective and diastereoselective intermolecular alkylation of Wieland–Miescher ketone derivative 9 and benzyl bromide 10.The core 6/6/6/6-fused backbone of dysideanones was efficiently constructed through an intramolecular radical cyclization reaction.Dysideanone G(6)was easily prepared on a gram-scale and dysideanones A,E,and F(1,4,and 5)were divergently transformed from dysideanone G(6)in one or two steps.
文摘在人类活动加重气候变暖的背景下,极端水文气象事件发生概率增加。数值模式作为研究水循环和极端水文事件的有效工具,已在全球范围内得到广泛应用。为深入理解气候变化背景下全球陆地水循环时空演变规律,揭示大气-陆面-水文互馈机制,大气-陆面-水文耦合过程模拟研究已成为国际大气、水文等学科研究的热点之一。本文首先回顾和梳理了大气-陆面-水文耦合模式的发展历程,阐明了大气-陆面-水文耦合模式WRF-Hydro(Weather Research and Forecasting Model Hydrological modeling system)的优势,并系统总结了WRF-Hydro模式的主要敏感性参数分析及模式在对地表径流、土壤湿度、能量水分循环以及相关大气和水文过程等方面的应用。最后探讨WRF-Hydro大气-陆面-水文耦合模式未来发展趋势,提出应着眼于发展有效的尺度转换方案、完善参数化方案以及开展流域内大气、水文变量时空分布高分辨率模拟等方面,以期系统提升耦合模式对大气、陆面过程及水文过程的刻画能力。
文摘黄河源区是黄河流域主要的产流区和水源涵养区,研究和探索该区域陆面水文过程对理解陆面过程及水文循环特征,揭示陆面—水文耦合过程具有重要的科学意义。本研究基于2009~2018年中国区域高时空分辨率地面气象要素驱动数据(China Meteorological Forcing Dataset,简称CMFD)、全球高分辨率降水数据集(Climate Prediction Center Morphing Technique,简称CMORPH)、热带降雨测量卫星(Tropical Rainfall Measuring Mission,简称TRMM)及全球陆地数据同化系统(Global Land Data Assimilation System,简称GLDAS)降水,评估了四类降水产品在黄河源区的降水精度,在此基础上,利用最优降水数据驱动独立运行的天气研究预报及水文耦合模型系统(Weather Research and Forecasting Model Hydrological modeling system,简称WRF-Hydro),探究该模式在黄河源区径流模拟的适用性。结果表明:四类降水产品均能够反映出降水的分布特征,但在量值及细节捕捉上存在显著差异。CMFD在不同时空尺度上都能很好地捕捉到降水的演变特征,其与日观测降水的相关系数达到0.99,均方根误差仅为0.25 mm。在表征降水能力方面,四类降水产品总体表现为CMFD>CMORPH>TRMM>GLDAS,CMFD的平均探测成功率(Critical Success Index,简称CSI)在0.93以上。经参数率定后的WRF-Hydro模式在黄河源区月径流模拟方面表现较好,率定期纳什系数(Nash-Sutcliffe efficiency coefficient,简称NSE)均在0.92以上,而验证期丰水年模拟结果明显好于枯水年(NSE=0.15),这与降水和径流的非线性程度有关。本研究方案和结果为亚寒带半干旱气候区大尺度流域水文模拟及径流预测提供了一定的参考价值。
文摘The article discusses engineering approaches to solving the problem of oil vapours in generators. Due to the design characteristics of each power plant, it is difficult to find a typical solution. Nevertheless, the article suggests ways to reduce the amount of oil mist. For their implementation, a calculation methodology based on the substitution scheme of the hydraulic path of the bearing support unit is created which takes into account the design features of the bearing and the parameters of the environment around the oil bath. The methodology employed is presented. The numerical method of modelling the aerodynamic fields of the entire hydro generator is used to estimate the air flows and pressures in the oil bath zone of the thrust bearing. Additionally, the method made it possible to track suspected oil particles that could get from the thrust-bearing bath into the surrounding area of the generator. Measures are proposed to reduce the level of oil mist through the competent design of the oil vapour removal system from the bearing bath.
文摘Poor design of ground water evacuation mechanisms is often blocked and leads to the rise of ground water behind the wall. As a result, free water behind the wall that is not quickly evacuated, increases the lateral pressure and thus favors overturning failure. The resolution of the overturning problem in cantilever retaining walls caused by hydro-mechanical interaction was studied. An analytical and numerical method was used to study this type of wall-floor interaction. Then Coulomb’s design criterion against overturning to develop a mathematical model that compute analytical factor of safety against overturning in different water conditions and heel lengths was used. The modeling and simulation of this system in the Cast3m software which took into account a wide variety of floor and wall properties were performed. The numerical factor of safety against rollover was obtained, and the graphs for the factor of safety versus heel length and immersion depth for both methods were plotted. From (0 ≤ Hw ≤ H/3), water effect is not dangerous to wall stability against overturning and from (H/3 Hw ≤ H), water effect is very dangerous to wall stability against overturning. For analytical and numerical methods, the heel can be predimensioned against overturning as: Lc: [0.27H 0.38H], [0.29H 0.43H] for 0 ≤Hw ≤ H/3;[0.33H 0.45H], [0.39H 0.53H] for H/3 Hw ≤ 2H/3;[0.5H 0.6H], [0.50H 0.67H] for 2H/3 Hw≤ H. The numerical method guaranteeing more safety than the analytical method, Cantilever retaining walls can thus be pre-dimensioned considering Clayey-Sand soil in hydro-mechanical conditions.
