Hand function impairment after stroke has become a key and difficult issue in clinical rehabilitation due to complex neural innervation and a long recovery cycle.Biofeedback technology combined with occupational thera...Hand function impairment after stroke has become a key and difficult issue in clinical rehabilitation due to complex neural innervation and a long recovery cycle.Biofeedback technology combined with occupational therapy can make up for the limitations of single therapy and provide a new solution for hand function rehabilitation after stroke.This paper systematically sorts out the theoretical basis and clinical research progress of biofeedback technology combined with occupational therapy in hand function rehabilitation after stroke,and looks forward to the future development direction,aiming to provide reference for clinical rehabilitation practice and scientific research.展开更多
Objective:This study is conducted to investigate the effects of occupational therapy(OT) with or without combined acupuncture for upper limb pain and hand functions among children with spastic hemiplegic cerebral pals...Objective:This study is conducted to investigate the effects of occupational therapy(OT) with or without combined acupuncture for upper limb pain and hand functions among children with spastic hemiplegic cerebral palsy.Methods:A total of 90 patients who met the inclusion criteria were enrolled in a three-arm randomized,placebo-controlled trial,and were allocated to mono-occupational therapy(OT) group(patients=30),OT combined with real-acupuncture(ORA) group(patients=30),and OT combined with placeboacupuncture(OPA) group(patients=30),respectively.In addition to receiving the conventional OT program as the basic treatment for total 8 weeks,patients in ORA and OPA group also received corresponding acupuncture treatment 5 days per week for the first two weeks,3 days per week for the next two weeks,2 days per week for another two weeks,and 1 day per week for the last two weeks.Non-communicating children’s pain checklist-revised scale(NCCPC-R) was used for assessing the upper limb pain among patients.Squeeze dynamometry,modified Ashworth scale(MAS),manual muscle testing(MMT),JebsenTaylor hand function test(JTHFT) and box and block test(BBT) were used for assessing various aspects of upper limb and hand functions among patients.Meanwhile,adverse effects were monitored and recorded.Results:After 8-week treatment,NCCPC-R global scores witnessed a dramatic decline in ORA group(P<0.05),but not in either OPA(P> 0.05) or OT group(P> 0.05).Dramatic increases were identified in both squeeze dynamometry scores and MMT scores in all three groups(all P <0.05).Furthermore,the increases of ORA group were more significant than those of another two groups(both P <0.05).There were no significant changes in MAS global scores in each group(all P> 0.05).The BBT global scores of all three groups significantly increased(all P <0.05) after treatment.Among them,the increase of the ORA group was more than that of the other two groups(P <0.05).The 8-week treatment also had a significant impact on several sub-tests of JTFHT in each group.No significant adverse event was reported.Conclusion:ORA is a potential and promising alternative therapy for mitigating upper limb pain as well as improving both upper limb and hand functions among children with spastic hemiplegic cerebral palsy.展开更多
This paper proposes an immersive training system for patients with hand dysfunction who can perform rehabilitation training independently. The system uses Leap Motion binocular vision sensors to collect human hand inf...This paper proposes an immersive training system for patients with hand dysfunction who can perform rehabilitation training independently. The system uses Leap Motion binocular vision sensors to collect human hand information, and uses the improved PCA<sub><img src="Edit_d6662636-9073-4fbd-855f-9a36e871d5a4.png" width="10" height="15" alt="" /></sub> (Principal Component Analysis) to perform data fusion on the real-time data collected by the sensor to obtain more hands with fewer principal components, and improve the stability and accuracy of the data. Immediately, the use of improved SVM<sub><img src="Edit_10c78725-e09e-4dcf-ae05-e21205df4acc.png" width="10" height="15" alt="" /></sub> (Support Vector Machine) and KNN<sub><img src="Edit_0ee97f55-2773-4b48-93b3-93f61aa25577.png" width="10" height="15" alt="" /></sub> (K-Nearest Neighbor Algorithm) for gesture recognition and classification is proposed to enable patients to perform rehabilitation training more effectively. Finally, the effective evaluation results of the rehabilitation effect of patients by the idea of AHP<sub><img src="Edit_70dd1964-28be-4137-afa5-9a184704f08e.png" width="10" height="15" alt="" /></sub> (Analytic Hierarchy Process) are taken as necessary reference factors for doctors to follow up treatment. Various experimental results show that the system has achieved the expected results and has a good application prospect.展开更多
Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for th...Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for the recovery of hand function.The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury.In this study,we explored the activation mode of the supplementary motor area during a motor imagery task.We investigated the plasticity of the central nervous system after brachial plexus injury,using the motor imagery task.Results from functional magnetic resonance imaging showed that after brachial plexus injury,the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas.This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task,thereby impacting brain remodeling.Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing,initiating and executing certain movements,which may be partly responsible for the unsatisfactory clinical recovery of hand function.展开更多
Background: Carpal Tunnel Syndrome (CTS) is the compression of the median nerve in carpal tunnel of wrist which leads to the typical symptoms of numbness, paresthesia and sometimes pain in the patient’s hand. The sym...Background: Carpal Tunnel Syndrome (CTS) is the compression of the median nerve in carpal tunnel of wrist which leads to the typical symptoms of numbness, paresthesia and sometimes pain in the patient’s hand. The symptoms are usually sensed in the first three radial fingers and the lateral side of the ring finger because these areas are innervated by the median nerve. Objective: To assess hand function among patient with Carpal Tunnel Syndrome (CTS). Methods: This was a descriptive study in which 41 subjects (27 females and 14 males) were included from Ghurki trust teaching hospital, Lahore and Shalamar hospital, Lahore (from August 2018 to October 2018) according to inclusion criteria. Samples were collected according to WHO (World Health Organization) calculator. Hand function was measured with Boston Carpal Tunnel Questionnaire (BCTQ). Results: Majority of the patients with CTS fell into mild functional severity and mild symptom severity. The mean score for functional severity was 2.34 and for symptom severity it was 2.97. Conclusion: Activities of daily living such as grasping, writing, gripping and carrying objects were affected by the symptoms of pain, numbness, tingling and weakness in the patients suffering from CTS.展开更多
Motor function changes in the unaffected hand of stroke patients with hemiplegia. These changes are often ignored by clinicians owing to the extent of motor disability of the affected hand. Finger tapping frequency an...Motor function changes in the unaffected hand of stroke patients with hemiplegia. These changes are often ignored by clinicians owing to the extent of motor disability of the affected hand. Finger tapping frequency and Lind-mark hand function score showed that the motor function of unaffected hands in stroke patients was poorer than that of a healthy control hand. After 2 weeks of rehabilitation treatment, motor function of the unaffected hand of stroke patients was obviously improved. Therefore, attention should also be paid to motor function in the unaffected hand of stroke patients with hemiplegia during rehabilitation.展开更多
There have been no studies reported on the difference in cortical activation during use of volar and dorsal hand splints.We attempted to investigate the difference in cortical activation in the somatosensory cortical ...There have been no studies reported on the difference in cortical activation during use of volar and dorsal hand splints.We attempted to investigate the difference in cortical activation in the somatosensory cortical area during use of volar and dorsal hand splints by functional magnetic resonance imaging（f MRI）.We recruited eight healthy volunteers.f MRI was performed while subjects who were fitted with volar or dorsal hand splints performed grasp-release movements.Regions of interest were placed on the primary motor cortex（M1）,primary somatosensory cortex（S1）,posterior parietal cortex（PPC）,and secondary somatosensory cortex（S2）.Results of group analysis of f MRI data showed that the total numbers of activated voxels in all ROIs were significantly higher during use of volar hand splint（3,376） compared with that（1,416） during use of dorsal hand splint.In each ROI,use of volar hand splint induced greater activation in all ROIs（M1：1,748,S1 ：1,455,PPC：23,and S2：150） compared with use of dorsal hand splint（M1：783,S1：625,PPC：0,and S2：8）.The peak activated value was also higher during use of volar hand splint（t-value：17.29） compared with that during use of dorsal hand splint（t-value：13.11）.Taken together,use of volar hand splint induced greater cortical activation relevant to somatosensory function than use of dorsal hand splint.This result would be important for the physiatrist and therapist to apply appropriate somatosensory input in patients with brain injury.展开更多
Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with isc...Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with ischemic stroke were divided into the treatment group and the control group(n=38 in each). Based on the Brunnstrom's stage of Xingnao Kaiqiao acupuncture combined with rehabilitation training was used in the treatment group, and the control group was given rehabilitation training. FuglMeyer Assessment of the upper extremity(FMA-UE), Action Research Arm Test(ARAT) and Simple Test for Evaluating hand Function(STEF) were adopted separately to compare scores before treatment and 8 weeks after treatment. Results: The difference was not statistically significant in the two groups of patients for comparison of FMA-UE, ARAT and STEF scores before treatment(P>0.05). The difference was statistically significant in the two groups of score comparison of FMA-UE, ARAT and STEF after treatment(P<0.05). Conclusion: The Xingnao Kaiqiao acupuncture has its unique advantages in improving recovery of motor function of upper limb and hand in recovery period after stroke.展开更多
Embodied semantics theory asserts that the meaning of action-related words is neurally represented through networks that overlap with or are identical to networks involved in sensory-motor processing. While some studi...Embodied semantics theory asserts that the meaning of action-related words is neurally represented through networks that overlap with or are identical to networks involved in sensory-motor processing. While some studies supporting this theory have focused on Chinese characters, less attention has been paid to their semantic radicals. Indeed, there is still disagreement about whether these radicals are processed independently. The present study investigated whether radicals are processed separately and, if so, whether this processing occurs in sensory-motor regions. Materials consisted of 72 high-frequency Chinese characters, with 18 in each of four categories： hand-action verbs with and without hand-radicals, and verbs not related to hand actions, with and without hand-radicals. Twenty-eight participants underwent functional MRI scans while reading the characters. Compared to characters without hand-radicals, reading characters with hand-radicals activated the right medial frontal gyrus. Verbs involving hand-action activated the left inferior parietal lobule, possibly reflecting integration of information in the radical with the semantic meaning of the verb. The findings may be consistent with embodied semantics theory and suggest that neural representation of radicals is indispensable in processing Chinese characters.展开更多
Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment w...Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment were randomly divided into an observation group and a control group, 30 cases in each one. The conventional medication, physical therapy, occupational therapy and other rehabilitation trainings were applied in both groups. In observation group, Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） were punctured. The assessment was performed with neurologie deficit scoring of the National Institutes of Health Stroke Scale （NIHSS）, hand motor function, walking ability and the modified Barthel index scale of the Activities of Daily Living （ADL） in both groups before and after treatment. Results After treatment, the scores of hand function, walking ability, ADL and NIHSS were improved in both groups as compared with those before treatment （all P〈0.01）. The improvements of hand function, walking ability and ADL ：in observation group were superior to those in control group （all P〈0.05）. Conclusion The conventional medication and rehabilitation trainings combined with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） ean obviously improve hand motor function, walking ability, the activities of daily living and rehabilitation efficacy in the patients with post-stroke hand motor impairment.展开更多
目的:腕手矫形器是一种常见的上肢功能障碍康复辅具,对脑卒中后手功能障碍患者的疗效存在争议。该文系统评价腕手矫形器对脑卒中患者手功能障碍的康复效果。方法:系统检索中国知网、万方、维普、SinoMed、PubMed、Embase、Web of Scienc...目的:腕手矫形器是一种常见的上肢功能障碍康复辅具,对脑卒中后手功能障碍患者的疗效存在争议。该文系统评价腕手矫形器对脑卒中患者手功能障碍的康复效果。方法:系统检索中国知网、万方、维普、SinoMed、PubMed、Embase、Web of Science、Cochrane Library等数据库公开发表的腕手矫形器在脑卒中患者手功能康复中应用的随机对照试验,其中试验组采用腕手矫形器和常规康复治疗,对照组采用常规康复治疗,检索时限为各数据库建库到2024年7月。由2位研究者独立开展文献筛选、提取资料,并依据Cochrane风险偏倚评估工具评价文献质量,使用RevMan 5.4软件进行Meta分析。结果:最终纳入8篇文献,共305例患者。Meta分析结果显示:试验组改良Ashworth评分低于对照组[MD=-0.24,95%CI(-0.36,-0.12),P<0.0001],Fugl-Meyer上肢运动功能评分和改良Barthel评分[SMD=0.97,95%CI(0.51,1.43),P<0.0001;SMD=1.00,95%CI(0.05,1.94),P=0.04]均高于对照组,两组握力比较差异无显著性意义[MD=-0.89,95%CI(-5.37,3.58),P=0.70]。结论:腕手矫形器能够降低脑卒中患者腕手关节肌张力,提高患者手运动功能与日常生活活动能力,但对患者握力无明显改善。需注意的是,研究总样本量仅305例,且部分指标(如握力)仅纳入2篇文献,统计效力不足,未来需更多大样本、高质量的随机对照试验进行验证。展开更多
目的:探讨透明质酸和脂肪胶填充对断指再植术后指体萎缩患者手功能及生活质量的影响。方法:选取2020年1月-2024年1月笔者科室收治的102例断指再植术后出现指体萎缩的患者作为研究对象,采用随机数字表法分为脂肪移植组和透明质酸组,每组5...目的:探讨透明质酸和脂肪胶填充对断指再植术后指体萎缩患者手功能及生活质量的影响。方法:选取2020年1月-2024年1月笔者科室收治的102例断指再植术后出现指体萎缩的患者作为研究对象,采用随机数字表法分为脂肪移植组和透明质酸组,每组51例,两组萎缩指体皮下分别填充脂肪胶和透明质酸。填充后随访1个月,对两组患者手功能[密歇根州手功能评估量表(Michigan Hand Outcomes Questionnaire,MHQ)]、两点辨别觉、生活质量(Barthel指数)、手功能优良率(中华医学会外科学会断指再植功能评定标准)及并发症进行评定,并进行统计比较。结果:填充1个月后,脂肪移植组患者疼痛评分低于透明质酸组,但外观、日常活动、工作情况、手功能满意度以及手整体功能评分均高于透明质酸组(P<0.05);脂肪移植组患者Barthel指数高于透明质酸组(P<0.05),两点辨别觉距离短于透明质酸组(P<0.05);两组患者手功能恢复优良率及并发症发生情况比较差异无统计学意义(P>0.05)。结论:脂肪胶填充对断指再植术后指体萎缩患者手功能和生活质量的改善作用优于透明质酸,且安全性好,值得临床推荐。展开更多
Sensory function is the most significant criterion when evaluating the prognosis of replanted fingers. Current clinical research has focused on surgical techniques and indications for finger replantation; however, few...Sensory function is the most significant criterion when evaluating the prognosis of replanted fingers. Current clinical research has focused on surgical techniques and indications for finger replantation; however, few studies have focused on recovery of finger sensory function af- ter replantation. This study retrospectively assessed data of eight patients who had undergone nine Zone I replantations of the fingertips in the First Affiliated Hospital of Sun Yat-sen University of China from July 2014 to January 2016. Variations in the extent of damage, with the residual vessels or nerves in some fingers being too short or even missing, prevented tension-free suture repair in some patients. Thus, re- pair of four of the nine fingertips included arteriovenous anastomosis, the remaining five undergoing arterial anastomosis during replanta- tion of the amputated fingers. Three patients underwent nerve repair, whereas the remaining six cases did not. Fingertip replantations were successful in all eight patients. Compared with the patients without vascular anastomosis, no obvious atrophy was visible in the fingertips of patients who did undergo vascular anastomosis during replantation and their sensory function did recover. Fingertip replantation pro- vides good sensory function and cosmetic outcomes when good artery and vein anastomoses have been created, even when digital nerves have not been repaired.展开更多
When watching someone performs an action, mirror neurons are activated in a way that is very similar to the activation that occurs when actually performing that action. Previous single-sample case studies indicate tha...When watching someone performs an action, mirror neurons are activated in a way that is very similar to the activation that occurs when actually performing that action. Previous single-sample case studies indicate that hand-action observation training may lead to activation and remodeling of mirror neuron systems, which include important language centers, and may improve language function in aphasia patients. In this randomized-block-design experiment, we recruited 24 aphasia patients from, Zhongda Hospital, Southeast University, China. The patients were divided into three groups where they underwent hand-action observation and repetition, dynamic-object observation and repetition, or conventional speech therapy. Training took place 5 days per week, 35 minutes per day, for 2 weeks. We assessed language function via picture naming tests for objects and actions and the Western Aphasia Battery. Among the participants, one patient, his wife and four healthy student volunteers underwent functional magnetic resonance imaging to analyze changes in brain activation during hand-action observation and dynamic-object observation. Results demonstrated that, compared with dynamic-object observation, hand-action observation led to greater performance with respect to the aphasia quotient and affiliated naming sub-tests and a greater Western Aphasia Battery test score. The overall effect was similar to that of conventional aphasia training, yet hand-action observation had advantages compared with conventional training in terms of vocabulary extraction and spontaneous speech. Thus, hand-action observation appears to more strongly activate the mirror neuron system compared with dynamic-object observation. The activated areas included Broca's area, Wernicke's area, and the supramarginal gyrus. These results suggest that hand-action observation combined with repetition might better improve language function in aphasia patients compared with dynamic-object observation combined with repetition. The therapeutic mechanism of this intervention may be associated with activation of additional mirror neuron systems, and may have implications for the possible repair and remodeling of damaged nerve networks. The study protocol was approved by the Ethical Committee of Nanjing Medical University, China(approval number: 2011-SRFA-086) on March 11, 2011. This trial has been registered in the ISRCTN Registry(ISRCTN84827527).展开更多
In order to solve fuzzy mathematical programming with soft constraints,the initial models must first be converted into crisp models.Membership functions are employed to describe the fuzzy right-hand side parameters ne...In order to solve fuzzy mathematical programming with soft constraints,the initial models must first be converted into crisp models.Membership functions are employed to describe the fuzzy right-hand side parameters needed to achieve this conversion.In some cases,echelon form membership functions(EFMFs)are required to depict the actual fuzzy situation.However,due to their discrete properties,fuzzy programming problems with such membership functions cannot be modeled by traditional methods.Motivated by these challenges,this paper introduces a novel absolute value representation modeling approach to formulate fuzzy programming using EFMFs.This approach can translate a discrete model to a continuous one which can then be easily solved.Finally,by means of a numerical example,the effectiveness of our new approach is demonstrated.展开更多
This paper presents a real-time Kinect- based hand pose estimation method. Different from model-based and appearance-based approaches, our approach retrieves continuous hand motion parameters in real time. First, the ...This paper presents a real-time Kinect- based hand pose estimation method. Different from model-based and appearance-based approaches, our approach retrieves continuous hand motion parameters in real time. First, the hand region is segmented from the depth image. Then, some specific feature points on the hand are located by the random forest classifier, and the relative displacements of these feature points are transformed to a rotation invariant feature vector. Finally, the system retrieves the hand joint parameters by applying the regression functions on the feature vectors. Experimental results are compared with the ground truth dataset obtained by a data glove to show the effectiveness of our approach. The effects of different distances and different rotation angles for the estimation accuracy are also evaluated.展开更多
文摘Hand function impairment after stroke has become a key and difficult issue in clinical rehabilitation due to complex neural innervation and a long recovery cycle.Biofeedback technology combined with occupational therapy can make up for the limitations of single therapy and provide a new solution for hand function rehabilitation after stroke.This paper systematically sorts out the theoretical basis and clinical research progress of biofeedback technology combined with occupational therapy in hand function rehabilitation after stroke,and looks forward to the future development direction,aiming to provide reference for clinical rehabilitation practice and scientific research.
基金Supported by University’s Scientific Research ProjectShanghai Sanda University:No.2021zz02-yj+1 种基金Special Project for Clinical ResearchShanghai Municipal Health Commission:No.20174Y0009.
文摘Objective:This study is conducted to investigate the effects of occupational therapy(OT) with or without combined acupuncture for upper limb pain and hand functions among children with spastic hemiplegic cerebral palsy.Methods:A total of 90 patients who met the inclusion criteria were enrolled in a three-arm randomized,placebo-controlled trial,and were allocated to mono-occupational therapy(OT) group(patients=30),OT combined with real-acupuncture(ORA) group(patients=30),and OT combined with placeboacupuncture(OPA) group(patients=30),respectively.In addition to receiving the conventional OT program as the basic treatment for total 8 weeks,patients in ORA and OPA group also received corresponding acupuncture treatment 5 days per week for the first two weeks,3 days per week for the next two weeks,2 days per week for another two weeks,and 1 day per week for the last two weeks.Non-communicating children’s pain checklist-revised scale(NCCPC-R) was used for assessing the upper limb pain among patients.Squeeze dynamometry,modified Ashworth scale(MAS),manual muscle testing(MMT),JebsenTaylor hand function test(JTHFT) and box and block test(BBT) were used for assessing various aspects of upper limb and hand functions among patients.Meanwhile,adverse effects were monitored and recorded.Results:After 8-week treatment,NCCPC-R global scores witnessed a dramatic decline in ORA group(P<0.05),but not in either OPA(P> 0.05) or OT group(P> 0.05).Dramatic increases were identified in both squeeze dynamometry scores and MMT scores in all three groups(all P <0.05).Furthermore,the increases of ORA group were more significant than those of another two groups(both P <0.05).There were no significant changes in MAS global scores in each group(all P> 0.05).The BBT global scores of all three groups significantly increased(all P <0.05) after treatment.Among them,the increase of the ORA group was more than that of the other two groups(P <0.05).The 8-week treatment also had a significant impact on several sub-tests of JTFHT in each group.No significant adverse event was reported.Conclusion:ORA is a potential and promising alternative therapy for mitigating upper limb pain as well as improving both upper limb and hand functions among children with spastic hemiplegic cerebral palsy.
文摘This paper proposes an immersive training system for patients with hand dysfunction who can perform rehabilitation training independently. The system uses Leap Motion binocular vision sensors to collect human hand information, and uses the improved PCA<sub><img src="Edit_d6662636-9073-4fbd-855f-9a36e871d5a4.png" width="10" height="15" alt="" /></sub> (Principal Component Analysis) to perform data fusion on the real-time data collected by the sensor to obtain more hands with fewer principal components, and improve the stability and accuracy of the data. Immediately, the use of improved SVM<sub><img src="Edit_10c78725-e09e-4dcf-ae05-e21205df4acc.png" width="10" height="15" alt="" /></sub> (Support Vector Machine) and KNN<sub><img src="Edit_0ee97f55-2773-4b48-93b3-93f61aa25577.png" width="10" height="15" alt="" /></sub> (K-Nearest Neighbor Algorithm) for gesture recognition and classification is proposed to enable patients to perform rehabilitation training more effectively. Finally, the effective evaluation results of the rehabilitation effect of patients by the idea of AHP<sub><img src="Edit_70dd1964-28be-4137-afa5-9a184704f08e.png" width="10" height="15" alt="" /></sub> (Analytic Hierarchy Process) are taken as necessary reference factors for doctors to follow up treatment. Various experimental results show that the system has achieved the expected results and has a good application prospect.
基金supported by the Youth Researcher Foundation of Shanghai Health Development Planning Commission,No.20124319
文摘Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for the recovery of hand function.The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury.In this study,we explored the activation mode of the supplementary motor area during a motor imagery task.We investigated the plasticity of the central nervous system after brachial plexus injury,using the motor imagery task.Results from functional magnetic resonance imaging showed that after brachial plexus injury,the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas.This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task,thereby impacting brain remodeling.Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing,initiating and executing certain movements,which may be partly responsible for the unsatisfactory clinical recovery of hand function.
文摘Background: Carpal Tunnel Syndrome (CTS) is the compression of the median nerve in carpal tunnel of wrist which leads to the typical symptoms of numbness, paresthesia and sometimes pain in the patient’s hand. The symptoms are usually sensed in the first three radial fingers and the lateral side of the ring finger because these areas are innervated by the median nerve. Objective: To assess hand function among patient with Carpal Tunnel Syndrome (CTS). Methods: This was a descriptive study in which 41 subjects (27 females and 14 males) were included from Ghurki trust teaching hospital, Lahore and Shalamar hospital, Lahore (from August 2018 to October 2018) according to inclusion criteria. Samples were collected according to WHO (World Health Organization) calculator. Hand function was measured with Boston Carpal Tunnel Questionnaire (BCTQ). Results: Majority of the patients with CTS fell into mild functional severity and mild symptom severity. The mean score for functional severity was 2.34 and for symptom severity it was 2.97. Conclusion: Activities of daily living such as grasping, writing, gripping and carrying objects were affected by the symptoms of pain, numbness, tingling and weakness in the patients suffering from CTS.
文摘Motor function changes in the unaffected hand of stroke patients with hemiplegia. These changes are often ignored by clinicians owing to the extent of motor disability of the affected hand. Finger tapping frequency and Lind-mark hand function score showed that the motor function of unaffected hands in stroke patients was poorer than that of a healthy control hand. After 2 weeks of rehabilitation treatment, motor function of the unaffected hand of stroke patients was obviously improved. Therefore, attention should also be paid to motor function in the unaffected hand of stroke patients with hemiplegia during rehabilitation.
基金supported by the National Research Foundation(NRF) of Korea Grant funded by the Korean Government(MSIP),No.2015R1A2A2A01004073
文摘There have been no studies reported on the difference in cortical activation during use of volar and dorsal hand splints.We attempted to investigate the difference in cortical activation in the somatosensory cortical area during use of volar and dorsal hand splints by functional magnetic resonance imaging（f MRI）.We recruited eight healthy volunteers.f MRI was performed while subjects who were fitted with volar or dorsal hand splints performed grasp-release movements.Regions of interest were placed on the primary motor cortex（M1）,primary somatosensory cortex（S1）,posterior parietal cortex（PPC）,and secondary somatosensory cortex（S2）.Results of group analysis of f MRI data showed that the total numbers of activated voxels in all ROIs were significantly higher during use of volar hand splint（3,376） compared with that（1,416） during use of dorsal hand splint.In each ROI,use of volar hand splint induced greater activation in all ROIs（M1：1,748,S1 ：1,455,PPC：23,and S2：150） compared with use of dorsal hand splint（M1：783,S1：625,PPC：0,and S2：8）.The peak activated value was also higher during use of volar hand splint（t-value：17.29） compared with that during use of dorsal hand splint（t-value：13.11）.Taken together,use of volar hand splint induced greater cortical activation relevant to somatosensory function than use of dorsal hand splint.This result would be important for the physiatrist and therapist to apply appropriate somatosensory input in patients with brain injury.
基金Shandong Province Traditional Chinese Medicine Technology Development Program。
文摘Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with ischemic stroke were divided into the treatment group and the control group(n=38 in each). Based on the Brunnstrom's stage of Xingnao Kaiqiao acupuncture combined with rehabilitation training was used in the treatment group, and the control group was given rehabilitation training. FuglMeyer Assessment of the upper extremity(FMA-UE), Action Research Arm Test(ARAT) and Simple Test for Evaluating hand Function(STEF) were adopted separately to compare scores before treatment and 8 weeks after treatment. Results: The difference was not statistically significant in the two groups of patients for comparison of FMA-UE, ARAT and STEF scores before treatment(P>0.05). The difference was statistically significant in the two groups of score comparison of FMA-UE, ARAT and STEF after treatment(P<0.05). Conclusion: The Xingnao Kaiqiao acupuncture has its unique advantages in improving recovery of motor function of upper limb and hand in recovery period after stroke.
基金supported by a grant from Ministry of Education,Taiwan,China under the Aiming for the Top University Plan at Taiwan Normal University,China
文摘Embodied semantics theory asserts that the meaning of action-related words is neurally represented through networks that overlap with or are identical to networks involved in sensory-motor processing. While some studies supporting this theory have focused on Chinese characters, less attention has been paid to their semantic radicals. Indeed, there is still disagreement about whether these radicals are processed independently. The present study investigated whether radicals are processed separately and, if so, whether this processing occurs in sensory-motor regions. Materials consisted of 72 high-frequency Chinese characters, with 18 in each of four categories： hand-action verbs with and without hand-radicals, and verbs not related to hand actions, with and without hand-radicals. Twenty-eight participants underwent functional MRI scans while reading the characters. Compared to characters without hand-radicals, reading characters with hand-radicals activated the right medial frontal gyrus. Verbs involving hand-action activated the left inferior parietal lobule, possibly reflecting integration of information in the radical with the semantic meaning of the verb. The findings may be consistent with embodied semantics theory and suggest that neural representation of radicals is indispensable in processing Chinese characters.
文摘Objective To observe the therapeutic effects of post-stroke hand motor impairment treated with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5）. Methods Sixty cases of post-stroke hand motor impairment were randomly divided into an observation group and a control group, 30 cases in each one. The conventional medication, physical therapy, occupational therapy and other rehabilitation trainings were applied in both groups. In observation group, Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） were punctured. The assessment was performed with neurologie deficit scoring of the National Institutes of Health Stroke Scale （NIHSS）, hand motor function, walking ability and the modified Barthel index scale of the Activities of Daily Living （ADL） in both groups before and after treatment. Results After treatment, the scores of hand function, walking ability, ADL and NIHSS were improved in both groups as compared with those before treatment （all P〈0.01）. The improvements of hand function, walking ability and ADL ：in observation group were superior to those in control group （all P〈0.05）. Conclusion The conventional medication and rehabilitation trainings combined with acupuncture at Zhongzhu （中渚 TE 3） and Waiguan （外关TE 5） ean obviously improve hand motor function, walking ability, the activities of daily living and rehabilitation efficacy in the patients with post-stroke hand motor impairment.
文摘目的:腕手矫形器是一种常见的上肢功能障碍康复辅具,对脑卒中后手功能障碍患者的疗效存在争议。该文系统评价腕手矫形器对脑卒中患者手功能障碍的康复效果。方法:系统检索中国知网、万方、维普、SinoMed、PubMed、Embase、Web of Science、Cochrane Library等数据库公开发表的腕手矫形器在脑卒中患者手功能康复中应用的随机对照试验,其中试验组采用腕手矫形器和常规康复治疗,对照组采用常规康复治疗,检索时限为各数据库建库到2024年7月。由2位研究者独立开展文献筛选、提取资料,并依据Cochrane风险偏倚评估工具评价文献质量,使用RevMan 5.4软件进行Meta分析。结果:最终纳入8篇文献,共305例患者。Meta分析结果显示:试验组改良Ashworth评分低于对照组[MD=-0.24,95%CI(-0.36,-0.12),P<0.0001],Fugl-Meyer上肢运动功能评分和改良Barthel评分[SMD=0.97,95%CI(0.51,1.43),P<0.0001;SMD=1.00,95%CI(0.05,1.94),P=0.04]均高于对照组,两组握力比较差异无显著性意义[MD=-0.89,95%CI(-5.37,3.58),P=0.70]。结论:腕手矫形器能够降低脑卒中患者腕手关节肌张力,提高患者手运动功能与日常生活活动能力,但对患者握力无明显改善。需注意的是,研究总样本量仅305例,且部分指标(如握力)仅纳入2篇文献,统计效力不足,未来需更多大样本、高质量的随机对照试验进行验证。
文摘目的:探讨透明质酸和脂肪胶填充对断指再植术后指体萎缩患者手功能及生活质量的影响。方法:选取2020年1月-2024年1月笔者科室收治的102例断指再植术后出现指体萎缩的患者作为研究对象,采用随机数字表法分为脂肪移植组和透明质酸组,每组51例,两组萎缩指体皮下分别填充脂肪胶和透明质酸。填充后随访1个月,对两组患者手功能[密歇根州手功能评估量表(Michigan Hand Outcomes Questionnaire,MHQ)]、两点辨别觉、生活质量(Barthel指数)、手功能优良率(中华医学会外科学会断指再植功能评定标准)及并发症进行评定,并进行统计比较。结果:填充1个月后,脂肪移植组患者疼痛评分低于透明质酸组,但外观、日常活动、工作情况、手功能满意度以及手整体功能评分均高于透明质酸组(P<0.05);脂肪移植组患者Barthel指数高于透明质酸组(P<0.05),两点辨别觉距离短于透明质酸组(P<0.05);两组患者手功能恢复优良率及并发症发生情况比较差异无统计学意义(P>0.05)。结论:脂肪胶填充对断指再植术后指体萎缩患者手功能和生活质量的改善作用优于透明质酸,且安全性好,值得临床推荐。
基金supported by a grant from the Department of Health of Guangdong Province of China,No.A2016018the Specialized Research Fund for the Doctoral Program of Higher Education,No.20120171120075+3 种基金a grant from the Science and Technology Project of Guangdong Province of China,No.2014A020212479a grant from the Science and Technology Project of Guangdong Province of China,No.2016A010103012a grant from the Science and Technology Program of Guangzhou City of China,No.201300000174a grant from the Doctoral Start-up Project of the Natural Science Foundation of Guangdong Province of China,No.2017A030310302
文摘Sensory function is the most significant criterion when evaluating the prognosis of replanted fingers. Current clinical research has focused on surgical techniques and indications for finger replantation; however, few studies have focused on recovery of finger sensory function af- ter replantation. This study retrospectively assessed data of eight patients who had undergone nine Zone I replantations of the fingertips in the First Affiliated Hospital of Sun Yat-sen University of China from July 2014 to January 2016. Variations in the extent of damage, with the residual vessels or nerves in some fingers being too short or even missing, prevented tension-free suture repair in some patients. Thus, re- pair of four of the nine fingertips included arteriovenous anastomosis, the remaining five undergoing arterial anastomosis during replanta- tion of the amputated fingers. Three patients underwent nerve repair, whereas the remaining six cases did not. Fingertip replantations were successful in all eight patients. Compared with the patients without vascular anastomosis, no obvious atrophy was visible in the fingertips of patients who did undergo vascular anastomosis during replantation and their sensory function did recover. Fingertip replantation pro- vides good sensory function and cosmetic outcomes when good artery and vein anastomoses have been created, even when digital nerves have not been repaired.
基金supported by the National Natural Science Foundation of China,No.81472163,81874035(to CLS)the General Project of University Philosophy and Social Science Research of China,No.2016SJB740015(to QY)+1 种基金the Science and Technology Plan Project of Zhangjiagang city of China in 2016,No.ZKS1615(to WLC)the Youth Science and Technology Project of Suzhou Health Development through Scientific Research and Education in 2018,No.KJXW2018059(to WLC)
文摘When watching someone performs an action, mirror neurons are activated in a way that is very similar to the activation that occurs when actually performing that action. Previous single-sample case studies indicate that hand-action observation training may lead to activation and remodeling of mirror neuron systems, which include important language centers, and may improve language function in aphasia patients. In this randomized-block-design experiment, we recruited 24 aphasia patients from, Zhongda Hospital, Southeast University, China. The patients were divided into three groups where they underwent hand-action observation and repetition, dynamic-object observation and repetition, or conventional speech therapy. Training took place 5 days per week, 35 minutes per day, for 2 weeks. We assessed language function via picture naming tests for objects and actions and the Western Aphasia Battery. Among the participants, one patient, his wife and four healthy student volunteers underwent functional magnetic resonance imaging to analyze changes in brain activation during hand-action observation and dynamic-object observation. Results demonstrated that, compared with dynamic-object observation, hand-action observation led to greater performance with respect to the aphasia quotient and affiliated naming sub-tests and a greater Western Aphasia Battery test score. The overall effect was similar to that of conventional aphasia training, yet hand-action observation had advantages compared with conventional training in terms of vocabulary extraction and spontaneous speech. Thus, hand-action observation appears to more strongly activate the mirror neuron system compared with dynamic-object observation. The activated areas included Broca's area, Wernicke's area, and the supramarginal gyrus. These results suggest that hand-action observation combined with repetition might better improve language function in aphasia patients compared with dynamic-object observation combined with repetition. The therapeutic mechanism of this intervention may be associated with activation of additional mirror neuron systems, and may have implications for the possible repair and remodeling of damaged nerve networks. The study protocol was approved by the Ethical Committee of Nanjing Medical University, China(approval number: 2011-SRFA-086) on March 11, 2011. This trial has been registered in the ISRCTN Registry(ISRCTN84827527).
文摘In order to solve fuzzy mathematical programming with soft constraints,the initial models must first be converted into crisp models.Membership functions are employed to describe the fuzzy right-hand side parameters needed to achieve this conversion.In some cases,echelon form membership functions(EFMFs)are required to depict the actual fuzzy situation.However,due to their discrete properties,fuzzy programming problems with such membership functions cannot be modeled by traditional methods.Motivated by these challenges,this paper introduces a novel absolute value representation modeling approach to formulate fuzzy programming using EFMFs.This approach can translate a discrete model to a continuous one which can then be easily solved.Finally,by means of a numerical example,the effectiveness of our new approach is demonstrated.
基金supported by NSC under Grand No.101-2221-E-468-030
文摘This paper presents a real-time Kinect- based hand pose estimation method. Different from model-based and appearance-based approaches, our approach retrieves continuous hand motion parameters in real time. First, the hand region is segmented from the depth image. Then, some specific feature points on the hand are located by the random forest classifier, and the relative displacements of these feature points are transformed to a rotation invariant feature vector. Finally, the system retrieves the hand joint parameters by applying the regression functions on the feature vectors. Experimental results are compared with the ground truth dataset obtained by a data glove to show the effectiveness of our approach. The effects of different distances and different rotation angles for the estimation accuracy are also evaluated.
