AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:...AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.展开更多
With the miniaturization of devices and the development of modern heating technologies,the generalization of heat conduction and thermoelastic coupling has become crucial,effectively emulating the thermodynamic behavi...With the miniaturization of devices and the development of modern heating technologies,the generalization of heat conduction and thermoelastic coupling has become crucial,effectively emulating the thermodynamic behavior of materials in ultrashort time scales.Theoretically,generalized heat conductive models are considered in this work.By analogy with mechanical viscoelastic models,this paper further enriches the heat conduction models and gives their one-dimensional physical expression.Numerically,the transient thermoelastic response of the slim strip material under thermal shock is investigated by applying the proposed models.First,the analytical solution in the Laplace domain is obtained by the Laplace transform.Then,the numerical results of the transient responses are obtained by the numerical inverse Laplace transform.Finally,the transient responses of different models are analyzed and compared,and the effects of material parameters are discussed.This work not only opens up new research perspectives on generalized heat conductive and thermoelastic coupling theories,but also is expected to be beneficial for the deeper understanding of the heat wave theory.展开更多
Let X be a real uniformly convex and uniformly smooth Banach space and C a nonempty closed and convex subset of X.Let Π_(C):X→C denote the generalized metric projection operator introduced by Alber in[1].In this pap...Let X be a real uniformly convex and uniformly smooth Banach space and C a nonempty closed and convex subset of X.Let Π_(C):X→C denote the generalized metric projection operator introduced by Alber in[1].In this paper,we define the Gâteaux directional differentiability of Π_(C).We investigate some properties of the Gâteaux directional differentiability of Π_(C).In particular,if C is a closed ball,or a closed and convex cone(including proper closed subspaces),or a closed and convex cylinder,then,we give the exact representations of the directional derivatives of Π_(C).By comparing the results in[12]and this paper,we see the significant difference between the directional derivatives of the generalized metric projection operator Π_(C) and the Gâteaux directional derivatives of the standard metric projection operator PC.展开更多
This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a dis...This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a distinctive phenomenon that while a majority of Chinese respondents trust the medical profession as a whole,significant distrust exists toward doctors'skills and ethics,particularly among older,urban,and higher income populations.Qualtatively,we employ Generalized Argumentation Theory to analyze Chinese clinical dialogues,identifying three kinds of prototypical argumentative patterns in situations of patient distrust.Methodologically,this article shows the value of combining statistical analysis with goal-oriented Generalized Argumentation research to reconcile the tricky trust phenomenon of Chinese doctor-patient communication.展开更多
This paper considers compactness of the commutator[b,I_(α)]i(i=1,2),where I_(α)is a bilinear fractional integral operator,and b is a function in generalized Campanato spaces with variable growth condition.The author...This paper considers compactness of the commutator[b,I_(α)]i(i=1,2),where I_(α)is a bilinear fractional integral operator,and b is a function in generalized Campanato spaces with variable growth condition.The author gives sufficient conditions for the compactness of[b,I_(α)],(i=1,2)from the product of generalized Morrey spaces to generalized Morrey spaces.展开更多
To study the Poisson theory of the generalized Birkhoff systems, the Lie algebra and the Poisson brackets were used to establish the Poisson theorem. The generalized Poisson condition for the first integral and the ge...To study the Poisson theory of the generalized Birkhoff systems, the Lie algebra and the Poisson brackets were used to establish the Poisson theorem. The generalized Poisson condition for the first integral and the generalized Poisson theorem of the generalized Birkhoff systems are obtained. An example is given to illustrate the application of the result.展开更多
Among all statements of Second Law, the existence and uniqueness of stable equilibrium, for each given value of energy content and composition of constituents of any system, have been adopted to define thermodynamic e...Among all statements of Second Law, the existence and uniqueness of stable equilibrium, for each given value of energy content and composition of constituents of any system, have been adopted to define thermodynamic entropy by means of the impossibility of Perpetual Motion Machine of the Second Kind (PMM2) which is a consequence of the Second Law. Equality of temperature, chemical potential and pressure in many-particle systems are proved to be necessary conditions for the stable equilibrium. The proofs assume the stable equilibrium and derive, by means of the Highest-Entropy Principle, equality of temperature, chemical potential and pressure as a consequence. A first novelty of the present research is to demonstrate that equality is also a sufficient condition, in addition to necessity, for stable equilibrium implying that stable equilibrium is a condition also necessary, in addition to sufficiency, for equality of temperature potential and pressure addressed to as generalized potential. The second novelty is that the proof of sufficiency of equality, or necessity of stable equilibrium, is achieved by means of a generalization of entropy property, derived from a generalized definition of exergy, both being state and additive properties accounting for heat, mass and work interactions of the system underpinning the definition of Highest-Generalized-Entropy Principle adopted in the proof.展开更多
The liquid cooling system(LCS)of fuel cells is challenged by significant time delays,model uncertainties,pump and fan coupling,and frequent disturbances,leading to overshoot and control oscillations that degrade tempe...The liquid cooling system(LCS)of fuel cells is challenged by significant time delays,model uncertainties,pump and fan coupling,and frequent disturbances,leading to overshoot and control oscillations that degrade temperature regulation performance.To address these challenges,we propose a composite control scheme combining fuzzy logic and a variable-gain generalized supertwisting algorithm(VG-GSTA).Firstly,a one-dimensional(1D)fuzzy logic controler(FLC)for the pump ensures stable coolant flow,while a two-dimensional(2D)FLC for the fan regulates the stack temperature near the reference value.The VG-GSTA is then introduced to eliminate steady-state errors,offering resistance to disturbances and minimizing control oscillations.The equilibrium optimizer is used to fine-tune VG-GSTA parameters.Co-simulation verifies the effectiveness of our method,demonstrating its advantages in terms of disturbance immunity,overshoot suppression,tracking accuracy and response speed.展开更多
Given two graphs G and H,the Ramsey number R(G,H)is the smallest positive integer N such that every 2-coloring of the edges of K_(N)contains either a red G or a blue H.Let K_(N-1)■K_(1,k)be the graph obtained from K_...Given two graphs G and H,the Ramsey number R(G,H)is the smallest positive integer N such that every 2-coloring of the edges of K_(N)contains either a red G or a blue H.Let K_(N-1)■K_(1,k)be the graph obtained from K_(N-1)by adding anew vertexνconnecting k vertices of K_(N-1).A graph G withχ(G)=k+1 is called edge-critical if G contains an edge e such thatχ(G-e)=k.A considerable amount of research has been conducted by previous scholars on Ramsey numbers ofgraphs.In this study,we show that for an edge-critical graph G with x(G)=k+1,when k≥2,1≥2,and n is sufficiently large,R(G,K_(1)+nK_(t))=knt+1 and r,(G,K_(1)+nK_(t))=(k-1)nt+1.展开更多
This paper introduced the concept of generalized quasidiagonal extension of C^(*)-algebras and gave some basic properties.We show that the extension algebra preserves quasidiagonality and finitary in generalized quasi...This paper introduced the concept of generalized quasidiagonal extension of C^(*)-algebras and gave some basic properties.We show that the extension algebra preserves quasidiagonality and finitary in generalized quasidiagonal extension.We give also an example of generalized quasidiagonal extension,which is not quasidiagonal extension.展开更多
A dominating induced matching(DIM)of G is an induced matching that dominates every edge of G.In this note,we completely determine the number of DIMs in the generalized Petersen graph P(n,k).We prove that if P(n,k)is a...A dominating induced matching(DIM)of G is an induced matching that dominates every edge of G.In this note,we completely determine the number of DIMs in the generalized Petersen graph P(n,k).We prove that if P(n,k)is a generalized Petersen graph with n=0(mod 5)and k=2,3(mod 5),then E(P(n,k))can be partitioned into five DIMs.Meanwhile,in the left cases k=0,1,4(mod 5),we build some counterexamples to show that there exist some P(n,k)'s which are DIM-free.展开更多
For nonlinear state estimation driven by non-Gaussian noise,the estimator is required to be updated iteratively.Since the iterative update approximates a linear process,it fails to capture the nonlinearity of observat...For nonlinear state estimation driven by non-Gaussian noise,the estimator is required to be updated iteratively.Since the iterative update approximates a linear process,it fails to capture the nonlinearity of observation models,and this further degrades filtering accuracy and consistency.Given the flaws of nonlinear iteration,this work incorporates a recursive strategy into generalized M-estimation rather than the iterative strategy.The proposed algorithm extends nonlinear recursion to nonlinear systems using the statistical linear regression method.The recursion allows for the gradual release of observation information and consequently enables the update to proceed along the nonlinear direction.Considering the correlated state and observation noise induced by recursions,a separately reweighting strategy is adopted to build a robust nonlinear system.Analogous to the nonlinear recursion,a robust nonlinear recursive update strategy is proposed,where the associated covariances and the observation noise statistics are updated recursively to ensure the consistency of observation noise statistics,thereby completing the nonlinear solution of the robust system.Compared with the iterative update strategies under non-Gaussian observation noise,the recursive update strategy can facilitate the estimator to achieve higher filtering accuracy,stronger robustness,and better consistency.Therefore,the proposed strategy is more suitable for the robust nonlinear filtering framework.展开更多
BACKGROUND Cervical spondylosis(CS)frequently co-occurs with generalized anxiety disorder(GAD),presenting a complex clinical challenge.Managing CS-related pain in patients with GAD is particularly challenging because ...BACKGROUND Cervical spondylosis(CS)frequently co-occurs with generalized anxiety disorder(GAD),presenting a complex clinical challenge.Managing CS-related pain in patients with GAD is particularly challenging because of the bidirectional relationship between pain and anxiety,necessitating integrated treatment strategies.AIM To evaluate the efficacy of electroacupuncture(EA)in treating CS-related pain and anxiety in patients with GAD.METHODS This retrospective cohort study analyzed data from 83 patients with CS-related pain and GAD who received EA treatment over 2-year period.Pain intensity was assessed using the visual analog scale,and anxiety symptoms were measured using the Hamilton Anxiety Rating Scale.Additionally,neuroinflammatory markers,including interleukin-6,tumor necrosis factor-alpha,and high-sensitivity C-reactive protein,were examined.Outcomes were evaluated at baseline,after 4 weeks,and after 8 weeks of treatment.RESULTS EA treatment significantly reduced CS-related pain(mean visual analog scale reduction:3.24±1.18;P<0.001)and improved anxiety symptoms(mean Hamilton Anxiety Rating Scale reduction:7.83±2.65;P<0.001)after 8 weeks of treatment.Neuroinflammatory markers also showed significant reductions,with interleukin-6 and tumor necrosis factor-alpha levels decreasing by 32.7%and 28.5%,respectively(P<0.01).Pain reduction was significantly correlated with improvements in anxiety symptoms(r=0.68;P<0.001)and a decrease in inflammatory markers(r=0.54;P<0.01).CONCLUSION EA demonstrates significant efficacy in reducing CS-related pain in patients with comorbid GAD,along with concurrent improvements in anxiety symptoms and neuroinflammatory profiles.These findings suggest that EA may offer a valuable integrative approach for managing this complex clinical presentation,potentially addressing both pain and anxiety through the modulation of neuroinflammatory pathways.展开更多
We construct the quantum fields presentation of the generalized universal character and the generalized B-type universal character,and by acting the quantum fields presentations to the constant 1,the generating functi...We construct the quantum fields presentation of the generalized universal character and the generalized B-type universal character,and by acting the quantum fields presentations to the constant 1,the generating functions are derived.Furthermore,we introduce two integrable systems known as the generalized UC(GUC)hierarchy and the generalized Btype UC(GBUC)hierarchy satisfied by the generalized universal character and the generalized B-type universal character,respectively.Based on infinite sequences of complex numbers,we further establish the multiparameter generalized universal character and the multiparameter generalized B-type universal character,which have been proved to be solutions of the GUC hierarchy and the GBUC hierarchy,respectively.展开更多
As space equipment become larger in size and more flexible,generalized mechanisms are being widely used in space-deployable structures.Dynamic modeling of large-scale generalized space-deployable mechanisms is challen...As space equipment become larger in size and more flexible,generalized mechanisms are being widely used in space-deployable structures.Dynamic modeling of large-scale generalized space-deployable mechanisms is challenging owing to the coupling between the deformation of flexible links and rigid body motion.This study develops a dynamic modeling method for generalized mechanisms using the local frame of the SE(3)Lie group.The model represents both rigid and flexible links within a unified Lie group setting.The expressions for the velocities of rigid links and deformation of flexible links are derived using the Lie algebra framework.The nonuniqueness of the degrees of freedom of generalized kinematic pairs is considered,and the velocity fields of kinematic pairs in different situations are expressed.The equations of motion are derived using Hamilton’s principle.Because the velocities are expressed in the local frame,the mass matrix in the equation is constant,which yields a compact and unified expression for the dynamic equation.A Lie group generalized-αtime integration method is adopted to ensure numerical stability and efficiency in simulating multibody systems with large rotations and deformations.Two numerical examples are studied to demonstrate a formulation that reflects the motion responses under varying configurations and loading conditions.This study broadens the application of the local frame of the Lie group formulation in space mechanisms and provides a new concept for dynamic modeling of generalized mechanisms.展开更多
Fractional calculus is widely used to deal with nonconservative dynamics because of its memorability and non-local properties.In this paper,the Herglotz principle with generalized operators is discussed,and the Herglo...Fractional calculus is widely used to deal with nonconservative dynamics because of its memorability and non-local properties.In this paper,the Herglotz principle with generalized operators is discussed,and the Herglotz type equations for nonholonomic systems are established.Then,the Noether symmetries are studied,and the conserved quantities are obtained.The results are extended to nonholonomic canonical systems,and the Herglotz type canonical equations and the Noether theorems are obtained.Two examples are provided to demonstrate the validity of the methods and results.展开更多
The existing analytical models for umbrella arch method(UAM)based on elastic foundation beams often overlook the influence of the surrounding soil beyond the beam edges on the shear stresses acting on the beam.Consequ...The existing analytical models for umbrella arch method(UAM)based on elastic foundation beams often overlook the influence of the surrounding soil beyond the beam edges on the shear stresses acting on the beam.Consequently,such models fail to adequately reflect the continuity characteristics of soil deformation.Leveraging the Pasternak foundation-Euler beam model,this study considers the generalized shear force on the beam to account for the influence of soil outside the beam ends on the shear stress.An analytical model for the deformation and internal forces of finite-length beams subjected to arbitrary loads is derived based on the initial parameter method under various conditions.The mechanical model of the elastic foundation beam for advanced umbrella arch under typical tunnel excavation cycles is established,yielding analytical solutions for the longitudinal response of the umbrella arch.The reliability of the analytical model is verified with the existing test data.The improved model addresses anomalies in existing models,such as abnormal upward deformation in the loosened segment and maximum deflection occurring within the soil mass.Additionally,dimensionless characteristic parameters reflecting the relative stiffness between the umbrella arch structure and the foundation soil are proposed.Results indicate that the magnitude of soil characteristic parameters significantly influences the deformation and internal forces of the umbrella arch.Within common ranges of soil values,the maximum deformation and internal forces of the umbrella arch under semi-logarithmic coordinates exhibit nearly linear decay with decreasing soil characteristic parameters.The impact of tunnel excavation height on the stress of unsupported sections of the umbrella arch is minor,but it is more significant for umbrella arch buried within the soil mass.Conversely,the influence of tunnel excavation advance on the umbrella arch is opposite.展开更多
In this present work,we propose the expected Bayesian and hierarchical Bayesian approaches to estimate the shape parameter and hazard rate under a generalized progressive hybrid censoring scheme for the Kumaraswamy di...In this present work,we propose the expected Bayesian and hierarchical Bayesian approaches to estimate the shape parameter and hazard rate under a generalized progressive hybrid censoring scheme for the Kumaraswamy distribution.These estimates have been obtained using gamma priors based on various loss functions such as squared error,entropy,weighted balance,and minimum expected loss functions.An investigation is carried out using Monte Carlo simulation to evaluate the effectiveness of the suggested estimators.The simulation provides a quantitative assessment of the estimates accuracy and efficiency under various conditions by comparing them in terms of mean squared error.Additionally,the monthly water capacity of the Shasta reservoir is examined to offer real-world examples of how the suggested estimations may be used and performed.展开更多
Background Polycystic ovarian syndrome(PCOS),a common endocrine disorder in reproductive-aged women,has substantial physical and psychological impacts.While the physical manifestations of PCOS are well established,the...Background Polycystic ovarian syndrome(PCOS),a common endocrine disorder in reproductive-aged women,has substantial physical and psychological impacts.While the physical manifestations of PCOS are well established,the psychological burden,especially anxiety,is understudied in Saudi Arabia.This study aimed to assess the prevalence of generalized anxiety disorder among females with PCOS compared to those without PCOS,and to identify the clinical and sociodemographic factors associated with anxiety in the Jazan region of Saudi Arabia.Methods A cross-sectional study was conducted between January and March 2023 using an Arabic self-administered online questionnaire distributed via social media platforms.The study recruited 410 reproductive-age females(≥18 years)from the Jazan region using convenience sampling.The questionnaire encompassed socio-demographic characteristics,economic indicators,medical history,PCOS symptoms,and the validated Generalized Anxiety Disorder-7(GAD-7)assessment tool.Results The prevalence of PCOS in the study population was 22.44%.Women with PCOS showed significantly higher anxiety levels compared to controls without PCOS(32.61%vs.22.33%).Biochemical hyperandrogenism was the strongest predictor of anxiety(OR=4.179).Menstrual irregularities demonstrated a dose-dependent relationship with anxiety risk,wherein participants with 2–3 months and≥3 months of amenorrhea had 2.5-and 3.3-times higher odds of anxiety compared to those with regular cycles(OR=2.451 and 3.314).Other PCOS-related dermatological manifestations were also associated with increased anxiety,including hirsutism(OR=1.745),alopecia(OR=2.285)and acne(OR=1.723).Marital status was a significant factor,with divorced/widowed females having 4.4-fold higher anxiety odds compared to single females(OR=4.371).Conclusion PCOS presents a significant psychological burden in Saudi women,with anxiety prevalence higher than the general population.The robust associations between PCOS manifestations and anxiety emphasize the need for integrated healthcare approaches that address both endocrine and mental health aspects.Routine psychological screening and support services should be incorporated into PCOS management protocols.展开更多
BACKGROUND Postpartum women are at an increased risk of generalized anxiety disorder(GAD),which can negatively affect both mental health and physical recovery.Pelvic floor dysfunction,common in this population,can exa...BACKGROUND Postpartum women are at an increased risk of generalized anxiety disorder(GAD),which can negatively affect both mental health and physical recovery.Pelvic floor dysfunction,common in this population,can exacerbate psychological distress.Although pelvic floor rehabilitation is effective in physical recovery,its potential to improve psychological outcomes,especially in women with GAD,remains underexplored.AIM To evaluate the effectiveness of an individualized pelvic floor rehabilitation program in improving anxiety,pelvic floor function,and quality of life in postpartum women with GAD.METHODS A retrospective study was performed to analyze 80 postpartum women with GAD who completed a 12-week individualized pelvic floor rehabilitation program(January 2020-December 2024),combining supervised pelvic floor muscle training and psychological support.Primary outcomes were changes in GAD-7 and Hamilton anxiety rating scale(HAM-A)scores and pelvic floor function measured by surface electromyography(sEMG).Secondary outcomes included World Health Organization quality of life-BREF,pelvic floor symptom severity,and impact on daily activities(pelvic floor impact questionnaire).Assessments were conducted at baseline and 6 and 12 weeks during the intervention period.RESULTS Significant improvements were observed in anxiety measures,with mean GAD-7 scores decreasing from 14.8±3.2 at baseline to 8.2±2.9 at week 12(P<0.001)and HAM-A scores decreasing from 22.6±4.5 to 12.4±3.8(P<0.001).Pelvic floor function showed substantial enhancement,with sEMG amplitude increasing from 22.4±5.6μV to 35.9±6.8μV(P<0.001).Quality of life improved across all domains,with the most significant improvements in psychological(28.5%increase)and physical health(25.8%increase).Program adherence was 91.5%for the supervised sessions,and no serious adverse events were reported.CONCLUSION Individualized pelvic floor rehabilitation training effectively improves both psychological and functional outcomes in postpartum women with GAD.The high adherence and significant outcomes make this integrated approach feasible and effective.展开更多
基金Supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(No.HR20C0026)the National Research Foundation of Korea(NRF)(No.RS-2023-00247504)the Patient-Centered Clinical Research Coordinating Center,funded by the Ministry of Health&Welfare,Republic of Korea(No.HC19C0276).
文摘AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.
基金Project supported by the Guangdong Basic and Applied Basic Research Foundation of China(No.2023A1515012809)the Natural Science Foundation of Shaanxi Province of China(No.2023-JC-YB-073)the Fundamental Research Funds for the Central Universities of China(No.D5000230066)。
文摘With the miniaturization of devices and the development of modern heating technologies,the generalization of heat conduction and thermoelastic coupling has become crucial,effectively emulating the thermodynamic behavior of materials in ultrashort time scales.Theoretically,generalized heat conductive models are considered in this work.By analogy with mechanical viscoelastic models,this paper further enriches the heat conduction models and gives their one-dimensional physical expression.Numerically,the transient thermoelastic response of the slim strip material under thermal shock is investigated by applying the proposed models.First,the analytical solution in the Laplace domain is obtained by the Laplace transform.Then,the numerical results of the transient responses are obtained by the numerical inverse Laplace transform.Finally,the transient responses of different models are analyzed and compared,and the effects of material parameters are discussed.This work not only opens up new research perspectives on generalized heat conductive and thermoelastic coupling theories,but also is expected to be beneficial for the deeper understanding of the heat wave theory.
文摘Let X be a real uniformly convex and uniformly smooth Banach space and C a nonempty closed and convex subset of X.Let Π_(C):X→C denote the generalized metric projection operator introduced by Alber in[1].In this paper,we define the Gâteaux directional differentiability of Π_(C).We investigate some properties of the Gâteaux directional differentiability of Π_(C).In particular,if C is a closed ball,or a closed and convex cone(including proper closed subspaces),or a closed and convex cylinder,then,we give the exact representations of the directional derivatives of Π_(C).By comparing the results in[12]and this paper,we see the significant difference between the directional derivatives of the generalized metric projection operator Π_(C) and the Gâteaux directional derivatives of the standard metric projection operator PC.
基金supported by the Fundamental Research Funds for the Chinese MOE Project of Key Research Institute of Humanities and Social Sciences at Universities(22JJD720022)the Central Universities of Jinan University(Grant No.23JNQMX55).
文摘This study aims to reveal the prototypical argumentative patterns employed in situations where patient distrust arises in China.Based on the quantitative analysis of data from a general social survey,we focus on a distinctive phenomenon that while a majority of Chinese respondents trust the medical profession as a whole,significant distrust exists toward doctors'skills and ethics,particularly among older,urban,and higher income populations.Qualtatively,we employ Generalized Argumentation Theory to analyze Chinese clinical dialogues,identifying three kinds of prototypical argumentative patterns in situations of patient distrust.Methodologically,this article shows the value of combining statistical analysis with goal-oriented Generalized Argumentation research to reconcile the tricky trust phenomenon of Chinese doctor-patient communication.
基金Supported by the Key Project of the Education Department of Fujian Province(JZ230054)the Sanming University's High-Level Talent Introduction Project(23YG09)the Natural Science Foundation of Fujian Province(2024J01903)。
文摘This paper considers compactness of the commutator[b,I_(α)]i(i=1,2),where I_(α)is a bilinear fractional integral operator,and b is a function in generalized Campanato spaces with variable growth condition.The author gives sufficient conditions for the compactness of[b,I_(α)],(i=1,2)from the product of generalized Morrey spaces to generalized Morrey spaces.
文摘To study the Poisson theory of the generalized Birkhoff systems, the Lie algebra and the Poisson brackets were used to establish the Poisson theorem. The generalized Poisson condition for the first integral and the generalized Poisson theorem of the generalized Birkhoff systems are obtained. An example is given to illustrate the application of the result.
文摘Among all statements of Second Law, the existence and uniqueness of stable equilibrium, for each given value of energy content and composition of constituents of any system, have been adopted to define thermodynamic entropy by means of the impossibility of Perpetual Motion Machine of the Second Kind (PMM2) which is a consequence of the Second Law. Equality of temperature, chemical potential and pressure in many-particle systems are proved to be necessary conditions for the stable equilibrium. The proofs assume the stable equilibrium and derive, by means of the Highest-Entropy Principle, equality of temperature, chemical potential and pressure as a consequence. A first novelty of the present research is to demonstrate that equality is also a sufficient condition, in addition to necessity, for stable equilibrium implying that stable equilibrium is a condition also necessary, in addition to sufficiency, for equality of temperature potential and pressure addressed to as generalized potential. The second novelty is that the proof of sufficiency of equality, or necessity of stable equilibrium, is achieved by means of a generalization of entropy property, derived from a generalized definition of exergy, both being state and additive properties accounting for heat, mass and work interactions of the system underpinning the definition of Highest-Generalized-Entropy Principle adopted in the proof.
基金Supported by the Major Science and Technology Project of Jilin Province(20220301010GX)the International Scientific and Technological Cooperation(20240402071GH).
文摘The liquid cooling system(LCS)of fuel cells is challenged by significant time delays,model uncertainties,pump and fan coupling,and frequent disturbances,leading to overshoot and control oscillations that degrade temperature regulation performance.To address these challenges,we propose a composite control scheme combining fuzzy logic and a variable-gain generalized supertwisting algorithm(VG-GSTA).Firstly,a one-dimensional(1D)fuzzy logic controler(FLC)for the pump ensures stable coolant flow,while a two-dimensional(2D)FLC for the fan regulates the stack temperature near the reference value.The VG-GSTA is then introduced to eliminate steady-state errors,offering resistance to disturbances and minimizing control oscillations.The equilibrium optimizer is used to fine-tune VG-GSTA parameters.Co-simulation verifies the effectiveness of our method,demonstrating its advantages in terms of disturbance immunity,overshoot suppression,tracking accuracy and response speed.
基金supported by the National Key Research and Development Program of China(2023YFA1010200,2020YFA0713100)the National Natural Science Foundation of China(12071453)the Innovation Program for Quantum Science and Technology(2021ZD0302902).
文摘Given two graphs G and H,the Ramsey number R(G,H)is the smallest positive integer N such that every 2-coloring of the edges of K_(N)contains either a red G or a blue H.Let K_(N-1)■K_(1,k)be the graph obtained from K_(N-1)by adding anew vertexνconnecting k vertices of K_(N-1).A graph G withχ(G)=k+1 is called edge-critical if G contains an edge e such thatχ(G-e)=k.A considerable amount of research has been conducted by previous scholars on Ramsey numbers ofgraphs.In this study,we show that for an edge-critical graph G with x(G)=k+1,when k≥2,1≥2,and n is sufficiently large,R(G,K_(1)+nK_(t))=knt+1 and r,(G,K_(1)+nK_(t))=(k-1)nt+1.
基金Supported by NSF of Jiangsu Province(No.BK20171421)。
文摘This paper introduced the concept of generalized quasidiagonal extension of C^(*)-algebras and gave some basic properties.We show that the extension algebra preserves quasidiagonality and finitary in generalized quasidiagonal extension.We give also an example of generalized quasidiagonal extension,which is not quasidiagonal extension.
基金Ming Chen was supported by National Key Research and Development Program of China(No.2024YFA1013900)。
文摘A dominating induced matching(DIM)of G is an induced matching that dominates every edge of G.In this note,we completely determine the number of DIMs in the generalized Petersen graph P(n,k).We prove that if P(n,k)is a generalized Petersen graph with n=0(mod 5)and k=2,3(mod 5),then E(P(n,k))can be partitioned into five DIMs.Meanwhile,in the left cases k=0,1,4(mod 5),we build some counterexamples to show that there exist some P(n,k)'s which are DIM-free.
基金co-supported by the National Natural Science Foundation of China(No.62303246,No.62103204)the China Postdoctoral Science Foundation(No.2023M731788)。
文摘For nonlinear state estimation driven by non-Gaussian noise,the estimator is required to be updated iteratively.Since the iterative update approximates a linear process,it fails to capture the nonlinearity of observation models,and this further degrades filtering accuracy and consistency.Given the flaws of nonlinear iteration,this work incorporates a recursive strategy into generalized M-estimation rather than the iterative strategy.The proposed algorithm extends nonlinear recursion to nonlinear systems using the statistical linear regression method.The recursion allows for the gradual release of observation information and consequently enables the update to proceed along the nonlinear direction.Considering the correlated state and observation noise induced by recursions,a separately reweighting strategy is adopted to build a robust nonlinear system.Analogous to the nonlinear recursion,a robust nonlinear recursive update strategy is proposed,where the associated covariances and the observation noise statistics are updated recursively to ensure the consistency of observation noise statistics,thereby completing the nonlinear solution of the robust system.Compared with the iterative update strategies under non-Gaussian observation noise,the recursive update strategy can facilitate the estimator to achieve higher filtering accuracy,stronger robustness,and better consistency.Therefore,the proposed strategy is more suitable for the robust nonlinear filtering framework.
文摘BACKGROUND Cervical spondylosis(CS)frequently co-occurs with generalized anxiety disorder(GAD),presenting a complex clinical challenge.Managing CS-related pain in patients with GAD is particularly challenging because of the bidirectional relationship between pain and anxiety,necessitating integrated treatment strategies.AIM To evaluate the efficacy of electroacupuncture(EA)in treating CS-related pain and anxiety in patients with GAD.METHODS This retrospective cohort study analyzed data from 83 patients with CS-related pain and GAD who received EA treatment over 2-year period.Pain intensity was assessed using the visual analog scale,and anxiety symptoms were measured using the Hamilton Anxiety Rating Scale.Additionally,neuroinflammatory markers,including interleukin-6,tumor necrosis factor-alpha,and high-sensitivity C-reactive protein,were examined.Outcomes were evaluated at baseline,after 4 weeks,and after 8 weeks of treatment.RESULTS EA treatment significantly reduced CS-related pain(mean visual analog scale reduction:3.24±1.18;P<0.001)and improved anxiety symptoms(mean Hamilton Anxiety Rating Scale reduction:7.83±2.65;P<0.001)after 8 weeks of treatment.Neuroinflammatory markers also showed significant reductions,with interleukin-6 and tumor necrosis factor-alpha levels decreasing by 32.7%and 28.5%,respectively(P<0.01).Pain reduction was significantly correlated with improvements in anxiety symptoms(r=0.68;P<0.001)and a decrease in inflammatory markers(r=0.54;P<0.01).CONCLUSION EA demonstrates significant efficacy in reducing CS-related pain in patients with comorbid GAD,along with concurrent improvements in anxiety symptoms and neuroinflammatory profiles.These findings suggest that EA may offer a valuable integrative approach for managing this complex clinical presentation,potentially addressing both pain and anxiety through the modulation of neuroinflammatory pathways.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12461048 and 12061051)the Natural Science Foundation of Inner Mongolia Autonomous Region(Grant No.2023MS01003)+2 种基金the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(Grant No.NJYT23096)the financial support from the Program of China Scholarships Council(Grant No.202306810054)for one year study at the University of Leedsthe support of Professor Ke Wu and Professor Weizhong Zhao at Capital Normal University,China。
文摘We construct the quantum fields presentation of the generalized universal character and the generalized B-type universal character,and by acting the quantum fields presentations to the constant 1,the generating functions are derived.Furthermore,we introduce two integrable systems known as the generalized UC(GUC)hierarchy and the generalized Btype UC(GBUC)hierarchy satisfied by the generalized universal character and the generalized B-type universal character,respectively.Based on infinite sequences of complex numbers,we further establish the multiparameter generalized universal character and the multiparameter generalized B-type universal character,which have been proved to be solutions of the GUC hierarchy and the GBUC hierarchy,respectively.
基金Supported by National Natural Science Foundation of China(Grant No.52475280)Key Laboratory Project of the Key Program of the Natural Science Basic Research Program of Shaanxi Province of China(Grant No.2025SYS-SYSZD-105)+1 种基金Natural Science Foundation of Shaanxi Province of China(Grant No.2025JC-YBQN-505)China Postdoctoral Science Foundation(Grant No.2024M752510).
文摘As space equipment become larger in size and more flexible,generalized mechanisms are being widely used in space-deployable structures.Dynamic modeling of large-scale generalized space-deployable mechanisms is challenging owing to the coupling between the deformation of flexible links and rigid body motion.This study develops a dynamic modeling method for generalized mechanisms using the local frame of the SE(3)Lie group.The model represents both rigid and flexible links within a unified Lie group setting.The expressions for the velocities of rigid links and deformation of flexible links are derived using the Lie algebra framework.The nonuniqueness of the degrees of freedom of generalized kinematic pairs is considered,and the velocity fields of kinematic pairs in different situations are expressed.The equations of motion are derived using Hamilton’s principle.Because the velocities are expressed in the local frame,the mass matrix in the equation is constant,which yields a compact and unified expression for the dynamic equation.A Lie group generalized-αtime integration method is adopted to ensure numerical stability and efficiency in simulating multibody systems with large rotations and deformations.Two numerical examples are studied to demonstrate a formulation that reflects the motion responses under varying configurations and loading conditions.This study broadens the application of the local frame of the Lie group formulation in space mechanisms and provides a new concept for dynamic modeling of generalized mechanisms.
基金supported by the National Natural Science Foundation of China(Grant No.12272248)the Postgraduate Research and Practice Innovation Program of Jiangsu Province of China(Grant No.KYCX23_3296).
文摘Fractional calculus is widely used to deal with nonconservative dynamics because of its memorability and non-local properties.In this paper,the Herglotz principle with generalized operators is discussed,and the Herglotz type equations for nonholonomic systems are established.Then,the Noether symmetries are studied,and the conserved quantities are obtained.The results are extended to nonholonomic canonical systems,and the Herglotz type canonical equations and the Noether theorems are obtained.Two examples are provided to demonstrate the validity of the methods and results.
基金Projects(52008403,52378421)supported by the National Natural Science Foundation of ChinaProject(2022-Key-10)supported by the Science and Technology Research and Development Program Project of China Railway Group LimitedProject(202207)supported by the Hunan Provincial Transportation Science and Technology,China。
文摘The existing analytical models for umbrella arch method(UAM)based on elastic foundation beams often overlook the influence of the surrounding soil beyond the beam edges on the shear stresses acting on the beam.Consequently,such models fail to adequately reflect the continuity characteristics of soil deformation.Leveraging the Pasternak foundation-Euler beam model,this study considers the generalized shear force on the beam to account for the influence of soil outside the beam ends on the shear stress.An analytical model for the deformation and internal forces of finite-length beams subjected to arbitrary loads is derived based on the initial parameter method under various conditions.The mechanical model of the elastic foundation beam for advanced umbrella arch under typical tunnel excavation cycles is established,yielding analytical solutions for the longitudinal response of the umbrella arch.The reliability of the analytical model is verified with the existing test data.The improved model addresses anomalies in existing models,such as abnormal upward deformation in the loosened segment and maximum deflection occurring within the soil mass.Additionally,dimensionless characteristic parameters reflecting the relative stiffness between the umbrella arch structure and the foundation soil are proposed.Results indicate that the magnitude of soil characteristic parameters significantly influences the deformation and internal forces of the umbrella arch.Within common ranges of soil values,the maximum deformation and internal forces of the umbrella arch under semi-logarithmic coordinates exhibit nearly linear decay with decreasing soil characteristic parameters.The impact of tunnel excavation height on the stress of unsupported sections of the umbrella arch is minor,but it is more significant for umbrella arch buried within the soil mass.Conversely,the influence of tunnel excavation advance on the umbrella arch is opposite.
基金funded by Researchers Supporting Project number(RSPD2025R969),King Saud University,Riyadh,Saudi Arabia.
文摘In this present work,we propose the expected Bayesian and hierarchical Bayesian approaches to estimate the shape parameter and hazard rate under a generalized progressive hybrid censoring scheme for the Kumaraswamy distribution.These estimates have been obtained using gamma priors based on various loss functions such as squared error,entropy,weighted balance,and minimum expected loss functions.An investigation is carried out using Monte Carlo simulation to evaluate the effectiveness of the suggested estimators.The simulation provides a quantitative assessment of the estimates accuracy and efficiency under various conditions by comparing them in terms of mean squared error.Additionally,the monthly water capacity of the Shasta reservoir is examined to offer real-world examples of how the suggested estimations may be used and performed.
文摘Background Polycystic ovarian syndrome(PCOS),a common endocrine disorder in reproductive-aged women,has substantial physical and psychological impacts.While the physical manifestations of PCOS are well established,the psychological burden,especially anxiety,is understudied in Saudi Arabia.This study aimed to assess the prevalence of generalized anxiety disorder among females with PCOS compared to those without PCOS,and to identify the clinical and sociodemographic factors associated with anxiety in the Jazan region of Saudi Arabia.Methods A cross-sectional study was conducted between January and March 2023 using an Arabic self-administered online questionnaire distributed via social media platforms.The study recruited 410 reproductive-age females(≥18 years)from the Jazan region using convenience sampling.The questionnaire encompassed socio-demographic characteristics,economic indicators,medical history,PCOS symptoms,and the validated Generalized Anxiety Disorder-7(GAD-7)assessment tool.Results The prevalence of PCOS in the study population was 22.44%.Women with PCOS showed significantly higher anxiety levels compared to controls without PCOS(32.61%vs.22.33%).Biochemical hyperandrogenism was the strongest predictor of anxiety(OR=4.179).Menstrual irregularities demonstrated a dose-dependent relationship with anxiety risk,wherein participants with 2–3 months and≥3 months of amenorrhea had 2.5-and 3.3-times higher odds of anxiety compared to those with regular cycles(OR=2.451 and 3.314).Other PCOS-related dermatological manifestations were also associated with increased anxiety,including hirsutism(OR=1.745),alopecia(OR=2.285)and acne(OR=1.723).Marital status was a significant factor,with divorced/widowed females having 4.4-fold higher anxiety odds compared to single females(OR=4.371).Conclusion PCOS presents a significant psychological burden in Saudi women,with anxiety prevalence higher than the general population.The robust associations between PCOS manifestations and anxiety emphasize the need for integrated healthcare approaches that address both endocrine and mental health aspects.Routine psychological screening and support services should be incorporated into PCOS management protocols.
基金2022 Annual Medical Science Research Project Plan of Hebei Province,No.20221111.
文摘BACKGROUND Postpartum women are at an increased risk of generalized anxiety disorder(GAD),which can negatively affect both mental health and physical recovery.Pelvic floor dysfunction,common in this population,can exacerbate psychological distress.Although pelvic floor rehabilitation is effective in physical recovery,its potential to improve psychological outcomes,especially in women with GAD,remains underexplored.AIM To evaluate the effectiveness of an individualized pelvic floor rehabilitation program in improving anxiety,pelvic floor function,and quality of life in postpartum women with GAD.METHODS A retrospective study was performed to analyze 80 postpartum women with GAD who completed a 12-week individualized pelvic floor rehabilitation program(January 2020-December 2024),combining supervised pelvic floor muscle training and psychological support.Primary outcomes were changes in GAD-7 and Hamilton anxiety rating scale(HAM-A)scores and pelvic floor function measured by surface electromyography(sEMG).Secondary outcomes included World Health Organization quality of life-BREF,pelvic floor symptom severity,and impact on daily activities(pelvic floor impact questionnaire).Assessments were conducted at baseline and 6 and 12 weeks during the intervention period.RESULTS Significant improvements were observed in anxiety measures,with mean GAD-7 scores decreasing from 14.8±3.2 at baseline to 8.2±2.9 at week 12(P<0.001)and HAM-A scores decreasing from 22.6±4.5 to 12.4±3.8(P<0.001).Pelvic floor function showed substantial enhancement,with sEMG amplitude increasing from 22.4±5.6μV to 35.9±6.8μV(P<0.001).Quality of life improved across all domains,with the most significant improvements in psychological(28.5%increase)and physical health(25.8%increase).Program adherence was 91.5%for the supervised sessions,and no serious adverse events were reported.CONCLUSION Individualized pelvic floor rehabilitation training effectively improves both psychological and functional outcomes in postpartum women with GAD.The high adherence and significant outcomes make this integrated approach feasible and effective.
