Laparoscopic and endoscopic cooperative surgery(LECS)is a hybrid minimally invasive technique originally developed for treatment of gastric submucosal tumors.Several modifications of LECS—including inverted LECS,non-...Laparoscopic and endoscopic cooperative surgery(LECS)is a hybrid minimally invasive technique originally developed for treatment of gastric submucosal tumors.Several modifications of LECS—including inverted LECS,non-exposed endoscopic wall-inversion surgery,and closed LECS have evolved over a period of time to address the earlier concerns about peritoneal contamination and tumor seeding.These innovations have led to the application of combined laparoendoscopic techniques to several gastrointestinal(GI)lesions such as the duodenum,colon,and rectum.This minireview explores the evolution,current applications,and future potential of laparoendoscopic surgery in GI diseases.展开更多
The additive manufacturing(AM)landscape has significantly transformed in alignment with Industry 4.0 principles,primarily driven by the integration of artificial intelligence(AI)and digital twins(DT).However,current i...The additive manufacturing(AM)landscape has significantly transformed in alignment with Industry 4.0 principles,primarily driven by the integration of artificial intelligence(AI)and digital twins(DT).However,current intelligent AM(IAM)systems face limitations such as fragmented AI tool usage and suboptimal human-machine interaction.This paper reviews existing IAM solutions,emphasizing control,monitoring,process autonomy,and end-to-end integration,and identifies key limitations,such as the absence of a high-level controller for global decision-making.To address these gaps,we propose a transition from IAM to autonomous AM,featuring a hierarchical framework with four integrated layers:knowledge,generative solution,operational,and cognitive.In the cognitive layer,AI agents notably enable machines to independently observe,analyze,plan,and execute operations that traditionally require human intervention.These capabilities streamline production processes and expand the possibilities for innovation,particularly in sectors like in-space manufacturing.Additionally,this paper discusses the role of AI in self-optimization and lifelong learning,positing that the future of AM will be characterized by a symbiotic relationship between human expertise and advanced autonomy,fostering a more adaptive,resilient manufacturing ecosystem.展开更多
Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical ca...Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical cancer as a major public health problem.Methods All data were extracted from the Global Cancer Observatory(GLOBOCAN)2022.Age-standardized incidence rate(ASIR)and mortality rates(ASMR)of cervical cancer were compared and linked to Human Development Index(HDI)between populations.The estimated annual percentage changes(EAPCs)were used to characterize the temporal trend in ASIR/ASMR,and demographic estimates were projected up to 2050.Results Globally,an estimated 662,044 cases(ASIR:14.12/100,000)and 348,709 deaths(ASMR:7.08/100,000)from cervical cancer occurred in 2022,corresponding to the fourth cause of cancer morbidity and mortality in women worldwide.Specifically,42%of cases and 39%of deaths occurred in China(23%and 16%)and India(19%and 23%).Both ASIR and ASMR of cervical cancer decreased with HDI,and similar decreasing links were observed for both early-onset(0–39 years)and late-onset(≥40 years)cervical cancer.Both ASIR and ASMR of overall cervical cancer showed decreasing trends during 2003–2012(EAPC:0.04%and-1.03%);however,upward trends were observed for early-onset cervical cancer(EAPC:1.16%and 0.57%).If national rates in 2022 remain stable,the estimated cases and deaths from cervical cancer are projected to increase by 56.8%and 80.7%up to 2050.Moreover,the projected increase of early-onset cervical cancer is mainly observed in transitioning countries,while decreased burden is expected in transitioned countries.Conclusions Cervical cancer remains a common cause of cancer death in many countries,especially in transitioning countries.Unless scaling-up preventive interventions,human papillomavirus(HPV)vaccination and cervical cancer screening,as well as systematic cooperation within government,civil societies,and private enterprises,the global burden of cervical cancer would be expected to increase in the future.展开更多
Ecological network(EN)identification and optimization is an essential research tool for safeguarding regional ecological security patterns and planning territorial space.Especially for the ecologically fragile inland ...Ecological network(EN)identification and optimization is an essential research tool for safeguarding regional ecological security patterns and planning territorial space.Especially for the ecologically fragile inland river basins,EN optimization is of significance in ensuring regional ecological security and virtuous cycle of ecosystems.In addition,EN is a dynamically changing structural system that is more applicable to the regional development by optimizing it from comprehensive future development perspective.EN of Shiyang River basin was constructed on account of the circuit theory,and land use/cover changes(LUCC)of the basin in 2035 was predicted by PLUS model,so as to explore the ecological conservation priorities and formulate optimization strategies.54 ecological sources(ESs)were identified,covering an area of 12,198 km^(2),mainly in the southern basin.133 ecological corridors(ECs)with an area of 3,176.92 km^(2)were extracted.38 ecological pinchpoints(EPs)and 22 ecological barriers(EBs)were identified respectively,which were mainly distributed in the lower basin.To effectively enhance the connectivity of EN in Minqin County,which has the worst ecological environment,we added five stepping stones based on the Ant Forest project.In addition,the optimal EPS is selected according to the development and limitation needs of inland river basins and the threat degree of warning points(WPs)under different scenarios.Scientific and reasonable optimization of future urban layout to prevent WPs can effectively alleviate the contradiction between ecological protection and economic development.The study is intended to provide basis for ecological sustainable development and rational planning territorial space in Shiyang River basin,as well as opinion for EN optimization in inland river basin.展开更多
Meeting the increasing demand for food and industrial products by the growing global population requires targeted efforts to improve crops,livestock,and microorganisms.Modern biotechnology,particularly genetic modific...Meeting the increasing demand for food and industrial products by the growing global population requires targeted efforts to improve crops,livestock,and microorganisms.Modern biotechnology,particularly genetic modification(GM)and genome-editing(GE)technologies,is crucial for food security and environmental sustainability.China,which is at the forefront of global biotechnological innovation and the rapid advancements in GM and GE technologies,has prioritized this field by implementing strategic programs such as the National High-tech Research&Development Program in 1986,the National Genetically Modified Organism New Variety Breeding Program in 2008,and the Biological Breeding-National Science and Technology Major Project in 2022.Many biotechnological products have been widely commercialized in China,including biofertilizers,animal feed,animal vaccines,pesticides,and GM crops such as cotton(Gossypium hirsutum),maize(Zea mays),and soybean(Glycine max).In this review,we summarize progress on the research and utilization of GM and GE organisms in China over the past 3 decades and provide perspectives on their further development.This review thus aims to promote worldwide academic exchange and contribute to the further development and commercial success of agricultural biotechnology.展开更多
Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the...Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the surgical treatment of lung cancer.Surgical resection continues to be the cornerstone of multidisciplinary treatment for patients with early-stage non-small cell lung cancer and a proportion of those with locally advanced disease.Moreover,recent years have seen developments in automatic control,biomechanics,robotics,image transmission,artificial intelligence,three-dimensional reconstruction and printing,biological pharmacy,and molecular biology.Therefore,there is now an increasing focus on how to integrate these technologies into lung cancer surgery to improve quality of life,resect the tumor accurately,expand the population that is suitable for surgical management,predict disease recurrence with better accuracy,and ultimately achieve long-term survival.This article systematically reviews the innovative achievements that may be detrimental to current clinical practice and in future clinical trials,and simultaneously provides a brief overview of the polyvagal perspective in this field.展开更多
Climate change is significantly impacting cotton production in the Tarim River Basin.The study investigated the climate change characteristics from 2021 to 2100 using climate change datasets simulated per the coupled ...Climate change is significantly impacting cotton production in the Tarim River Basin.The study investigated the climate change characteristics from 2021 to 2100 using climate change datasets simulated per the coupled model inter-comparison project phase six(CMIP6)climatic patterns under the shared socioeconomic pathways SSP2-4.5 and SSP5-8.5.The DSSAT-CROPGROCotton model,along with stepwise multiple regression analyses,was used to simulate changes in the potential yield of seed cotton due to climate change.The results show that while future temperatures in the Tarim River Basin will rise significantly,changes in precipitation and radiation during the cotton-growing season are minimal.Seed cotton yields are more sensitive to low temperatures than to precipitation and radiation.The potential yield of seed cotton under the SSP2-4.5 scenario would increase by 14.8%,23.7%,29.0%,and 29.4%in the 2030S,2050S,2070S,and 2090S,respectively.In contrast,under the SSP5-8.5 scenario,the potential yield of seed cotton would see increases of 17.5%,27.1%,30.1%,and 22.6%,respectively.Except for the 2090s under the SSP5-8.5 scenario,future seed cotton production can withstand a 10%to 20%deficit in irrigation.These findings will help develop climate change adaptation strategies for cotton cultivation.展开更多
BACKGROUND Gastrointestinal(GI)manifestations are prevalent in genetic myopathies,posing significant diagnostic and management challenges.AIM To synthesize evidence on the diagnostic approaches,management strategies,p...BACKGROUND Gastrointestinal(GI)manifestations are prevalent in genetic myopathies,posing significant diagnostic and management challenges.AIM To synthesize evidence on the diagnostic approaches,management strategies,patient perspectives,and future research directions regarding GI symptoms in genetic myopathies.METHODS A systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.We searched PubMed,Scopus,EMBASE,and Web of Science from inception to December 2024.Eligible studies reported GI manifestations in genetic myopathies,including clinical evaluations,imaging,physiological tests,histopathology,and genetic analyses.Inclusion criteria encompassed original research studies,review articles,case reports,and clinical guidelines published in peer-reviewed journals.Exclusion criteria included conference abstracts without full-text availability and non-peer-reviewed sources.Two independent reviewers screened studies and extracted data.They assessed methodological quality using the Newcastle-Ottawa Scale for observational studies,A MeaSurement Tool to Assess Systematic Reviews for systematic reviews,and the Joanna Briggs Institute checklist for case reports.A systematic narrative synthesis was employed to summarize the findings.RESULTS A total of 234 studies met the inclusion criteria.GI manifestations varied widely,with dysphagia,gastroesophageal reflux,abdominal pain,constipation,diarrhea,and fecal incontinence being the most frequently reported symptoms.The included studies highlighted a multidisciplinary diagnostic approach incorporating clinical assessment,imaging,physiological testing,histopathology,and genetic testing.Management strategies ranged from dietary interventions and rehabilitative therapies to pharmacological treatments and surgical procedures.Patient perspectives underscored the significant impact of GI symptoms on quality of life,social interactions,and emotional well-being.The main limitations of the included studies were high heterogeneity in study design,small sample sizes,and the potential risk of bias due to limited methodological rigor in some reports.CONCLUSION This review underscores the complexity of GI manifestations in genetic myopathies and the need for a comprehensive,multidisciplinary management approach.Future research should focus on elucidating molecular mechanisms,identifying biomarkers,and developing targeted therapies to improve patient outcomes.The findings have implications for both clinical practice and public health,emphasizing the necessity of early diagnosis and personalized management strategies.展开更多
Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belongi...Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.展开更多
What will our future life be like in China? We classmates imagine our future in China in our class meeting. The results are as follows:Some students think in 2030, our life will be much more colorful, and we can do al...What will our future life be like in China? We classmates imagine our future in China in our class meeting. The results are as follows:Some students think in 2030, our life will be much more colorful, and we can do almost anything(1) on the Internet including seeing a doctor. Most of us think that in 2035。展开更多
Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
The concept of a community with a shared future for humanity is the core idea of Xi Jinping thought on diplomacy.Since its introduction,this concept has been steadily advanced across various levels and sectors,yieldin...The concept of a community with a shared future for humanity is the core idea of Xi Jinping thought on diplomacy.Since its introduction,this concept has been steadily advanced across various levels and sectors,yielding tangible and meaningful results.Within Chinese academia,the idea of a community with a shared future for humanity,along with the important idea of a maritime community with a shared future,has been integrated into research on South China Sea issues.Scholars have explored China’s approach to establishing regional order in the South China Sea from multiple perspectives,including territorial dispute resolution,maritime rights and interests’protection,environmental conservation,and port cooperation.展开更多
From April 8 to 9,2025,the Cent ral Conference on Work Related to Neighboring Countries was held in Beijing.The conference systematically summarized the achievements and experience of China's neighborhood work in ...From April 8 to 9,2025,the Cent ral Conference on Work Related to Neighboring Countries was held in Beijing.The conference systematically summarized the achievements and experience of China's neighborhood work in the new era,scientifically analyzed the situation,clarified the goals,tasks,ideas,and measures for neighborhood work in the coming period,and emphasized the need to focus on building a community with a shared future with neighboring countries,striving to break new ground in neighborhood work.展开更多
As an important part of China's neighborhood,Southeast Asia has always been a high priority in China's neighborhood diplomacy,playing a benchmark and example-setting role in China's drive to build a commun...As an important part of China's neighborhood,Southeast Asia has always been a high priority in China's neighborhood diplomacy,playing a benchmark and example-setting role in China's drive to build a community with a shared future with neighboring countries.Shortly after the 2025 Central Conference on Work Related to Neighboring Countries,Chinese President Xi Jinping paid state visits to Vietnam,Malaysia,and Cambodia.展开更多
February 10-12, Sophia Antipolis, France The ETSI Artificial Intelligence Conference—How Standardization is Shaping the Future of AI will take place faceto-face on February 10-12, 2025, in France.The ETSI AI Conferen...February 10-12, Sophia Antipolis, France The ETSI Artificial Intelligence Conference—How Standardization is Shaping the Future of AI will take place faceto-face on February 10-12, 2025, in France.The ETSI AI Conference has been designed to provide attendees with the unique opportunity to exchange with AI subject-experts and learn about the state of the art work that is being done in AI-related standardization, regulation and service deployments.展开更多
Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from ...Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from the“shuttle effect”and sluggish ion transport kinetics due to the dissolution of sodium polysulfides and poor conductivity of sulfur.MXenes,as 2D transition metal carbides/nitrides,have exhibited excellent conductivity,diverse structure and tunable surface groups,particularly playing a crucial role in inhibiting polysulfide shuttle and sodium dendrite growth.In this review,achievements and advancements of MXene-based Na-S batteries are discussed,including applications of a sulfur cathode,separator,interlayer between separator and cathode,and sodium anode.In the end,perspectives and challenges on the future development of MXene-based materials in Na-S batteries are proposed.展开更多
Mental healthcare in Ethiopia is underutilized due to a lack of resources and skilled practitioners.Psychological counselling offers unique intervention possibilities because of its focus on a wide range of mental hea...Mental healthcare in Ethiopia is underutilized due to a lack of resources and skilled practitioners.Psychological counselling offers unique intervention possibilities because of its focus on a wide range of mental health and social justice issues.This literature review tracks the historical development of the profession of psychological counselling in Ethiopia to establish what has been achieved to date and the development challenges.Key achievements include recognition of the profession by the Ministry of Education,growing public awareness,and increasing capacity of practitioners skilled in psychological counselling.Challenges include limited contextually relevant training,poor representation of the profession within Ministry of Health policies,poor public and government mental health literacy,and a lack of regulatory frameworks.Postgraduate training would benefit from more culturally,contextually,and linguistically appropriate evidence-based,indigenous psychology practices.The profession would benefit from engagement in government policy development that promotes mental health,and professional regulatory bodies to hold practitioners accountable to professional standards and ethical practice.展开更多
The 2025 Central Conference on Work Related to Neighboring Countries stressed that China's neighborhood is“a vital foundation for achieving development and prosperity,a key front for safeguarding national securit...The 2025 Central Conference on Work Related to Neighboring Countries stressed that China's neighborhood is“a vital foundation for achieving development and prosperity,a key front for safeguarding national security,a priority area in managing overall diplomacy,and a crucial link in promoting the building of a community with a shared future for mankind.”展开更多
文摘Laparoscopic and endoscopic cooperative surgery(LECS)is a hybrid minimally invasive technique originally developed for treatment of gastric submucosal tumors.Several modifications of LECS—including inverted LECS,non-exposed endoscopic wall-inversion surgery,and closed LECS have evolved over a period of time to address the earlier concerns about peritoneal contamination and tumor seeding.These innovations have led to the application of combined laparoendoscopic techniques to several gastrointestinal(GI)lesions such as the duodenum,colon,and rectum.This minireview explores the evolution,current applications,and future potential of laparoendoscopic surgery in GI diseases.
基金funded by the MUREP High Volume project(80NSSC22M0132)through the U.S.NASA Office of STEM Engagementthe SMART IAC Project(DE-EE0009726)through the U.S.Department of Energy Office of Manufacturing and Energy Supply Chainssupport of San Diego Supercomputer Center(SDSC)National Research Platform(NRP)Nautilus sponsored by the U.S.NSF(2100237,2120019)。
文摘The additive manufacturing(AM)landscape has significantly transformed in alignment with Industry 4.0 principles,primarily driven by the integration of artificial intelligence(AI)and digital twins(DT).However,current intelligent AM(IAM)systems face limitations such as fragmented AI tool usage and suboptimal human-machine interaction.This paper reviews existing IAM solutions,emphasizing control,monitoring,process autonomy,and end-to-end integration,and identifies key limitations,such as the absence of a high-level controller for global decision-making.To address these gaps,we propose a transition from IAM to autonomous AM,featuring a hierarchical framework with four integrated layers:knowledge,generative solution,operational,and cognitive.In the cognitive layer,AI agents notably enable machines to independently observe,analyze,plan,and execute operations that traditionally require human intervention.These capabilities streamline production processes and expand the possibilities for innovation,particularly in sectors like in-space manufacturing.Additionally,this paper discusses the role of AI in self-optimization and lifelong learning,positing that the future of AM will be characterized by a symbiotic relationship between human expertise and advanced autonomy,fostering a more adaptive,resilient manufacturing ecosystem.
基金supported by the National Key R&D Program of China(grant number:2021YFC2500400)National Natural Science Foundation of China(grant numbers:82172894,82073028,82204121)China Postdoctoral Science Foundation(grant number:2023M742617).
文摘Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical cancer as a major public health problem.Methods All data were extracted from the Global Cancer Observatory(GLOBOCAN)2022.Age-standardized incidence rate(ASIR)and mortality rates(ASMR)of cervical cancer were compared and linked to Human Development Index(HDI)between populations.The estimated annual percentage changes(EAPCs)were used to characterize the temporal trend in ASIR/ASMR,and demographic estimates were projected up to 2050.Results Globally,an estimated 662,044 cases(ASIR:14.12/100,000)and 348,709 deaths(ASMR:7.08/100,000)from cervical cancer occurred in 2022,corresponding to the fourth cause of cancer morbidity and mortality in women worldwide.Specifically,42%of cases and 39%of deaths occurred in China(23%and 16%)and India(19%and 23%).Both ASIR and ASMR of cervical cancer decreased with HDI,and similar decreasing links were observed for both early-onset(0–39 years)and late-onset(≥40 years)cervical cancer.Both ASIR and ASMR of overall cervical cancer showed decreasing trends during 2003–2012(EAPC:0.04%and-1.03%);however,upward trends were observed for early-onset cervical cancer(EAPC:1.16%and 0.57%).If national rates in 2022 remain stable,the estimated cases and deaths from cervical cancer are projected to increase by 56.8%and 80.7%up to 2050.Moreover,the projected increase of early-onset cervical cancer is mainly observed in transitioning countries,while decreased burden is expected in transitioned countries.Conclusions Cervical cancer remains a common cause of cancer death in many countries,especially in transitioning countries.Unless scaling-up preventive interventions,human papillomavirus(HPV)vaccination and cervical cancer screening,as well as systematic cooperation within government,civil societies,and private enterprises,the global burden of cervical cancer would be expected to increase in the future.
基金funded by the National Natural Science Foundation of China(Grant No.42101276)。
文摘Ecological network(EN)identification and optimization is an essential research tool for safeguarding regional ecological security patterns and planning territorial space.Especially for the ecologically fragile inland river basins,EN optimization is of significance in ensuring regional ecological security and virtuous cycle of ecosystems.In addition,EN is a dynamically changing structural system that is more applicable to the regional development by optimizing it from comprehensive future development perspective.EN of Shiyang River basin was constructed on account of the circuit theory,and land use/cover changes(LUCC)of the basin in 2035 was predicted by PLUS model,so as to explore the ecological conservation priorities and formulate optimization strategies.54 ecological sources(ESs)were identified,covering an area of 12,198 km^(2),mainly in the southern basin.133 ecological corridors(ECs)with an area of 3,176.92 km^(2)were extracted.38 ecological pinchpoints(EPs)and 22 ecological barriers(EBs)were identified respectively,which were mainly distributed in the lower basin.To effectively enhance the connectivity of EN in Minqin County,which has the worst ecological environment,we added five stepping stones based on the Ant Forest project.In addition,the optimal EPS is selected according to the development and limitation needs of inland river basins and the threat degree of warning points(WPs)under different scenarios.Scientific and reasonable optimization of future urban layout to prevent WPs can effectively alleviate the contradiction between ecological protection and economic development.The study is intended to provide basis for ecological sustainable development and rational planning territorial space in Shiyang River basin,as well as opinion for EN optimization in inland river basin.
基金Biological Breeding-National Science and Technology Major Project(2022ZD04021).
文摘Meeting the increasing demand for food and industrial products by the growing global population requires targeted efforts to improve crops,livestock,and microorganisms.Modern biotechnology,particularly genetic modification(GM)and genome-editing(GE)technologies,is crucial for food security and environmental sustainability.China,which is at the forefront of global biotechnological innovation and the rapid advancements in GM and GE technologies,has prioritized this field by implementing strategic programs such as the National High-tech Research&Development Program in 1986,the National Genetically Modified Organism New Variety Breeding Program in 2008,and the Biological Breeding-National Science and Technology Major Project in 2022.Many biotechnological products have been widely commercialized in China,including biofertilizers,animal feed,animal vaccines,pesticides,and GM crops such as cotton(Gossypium hirsutum),maize(Zea mays),and soybean(Glycine max).In this review,we summarize progress on the research and utilization of GM and GE organisms in China over the past 3 decades and provide perspectives on their further development.This review thus aims to promote worldwide academic exchange and contribute to the further development and commercial success of agricultural biotechnology.
基金supported by grants from the Shenzhen Key Medical Discipline Construction Fund(number SZXK075)the Sanming Project of Medicine in Shenzhen(number SZSM201612097)the National Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Shenzhen(number E010322008).
文摘Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the surgical treatment of lung cancer.Surgical resection continues to be the cornerstone of multidisciplinary treatment for patients with early-stage non-small cell lung cancer and a proportion of those with locally advanced disease.Moreover,recent years have seen developments in automatic control,biomechanics,robotics,image transmission,artificial intelligence,three-dimensional reconstruction and printing,biological pharmacy,and molecular biology.Therefore,there is now an increasing focus on how to integrate these technologies into lung cancer surgery to improve quality of life,resect the tumor accurately,expand the population that is suitable for surgical management,predict disease recurrence with better accuracy,and ultimately achieve long-term survival.This article systematically reviews the innovative achievements that may be detrimental to current clinical practice and in future clinical trials,and simultaneously provides a brief overview of the polyvagal perspective in this field.
基金supported by the Science and Technology Program of Xinjiang Construction Corps(No.2024AB064)the National Natural Science Foundation of China(Nos.41975044,42001314)。
文摘Climate change is significantly impacting cotton production in the Tarim River Basin.The study investigated the climate change characteristics from 2021 to 2100 using climate change datasets simulated per the coupled model inter-comparison project phase six(CMIP6)climatic patterns under the shared socioeconomic pathways SSP2-4.5 and SSP5-8.5.The DSSAT-CROPGROCotton model,along with stepwise multiple regression analyses,was used to simulate changes in the potential yield of seed cotton due to climate change.The results show that while future temperatures in the Tarim River Basin will rise significantly,changes in precipitation and radiation during the cotton-growing season are minimal.Seed cotton yields are more sensitive to low temperatures than to precipitation and radiation.The potential yield of seed cotton under the SSP2-4.5 scenario would increase by 14.8%,23.7%,29.0%,and 29.4%in the 2030S,2050S,2070S,and 2090S,respectively.In contrast,under the SSP5-8.5 scenario,the potential yield of seed cotton would see increases of 17.5%,27.1%,30.1%,and 22.6%,respectively.Except for the 2090s under the SSP5-8.5 scenario,future seed cotton production can withstand a 10%to 20%deficit in irrigation.These findings will help develop climate change adaptation strategies for cotton cultivation.
文摘BACKGROUND Gastrointestinal(GI)manifestations are prevalent in genetic myopathies,posing significant diagnostic and management challenges.AIM To synthesize evidence on the diagnostic approaches,management strategies,patient perspectives,and future research directions regarding GI symptoms in genetic myopathies.METHODS A systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.We searched PubMed,Scopus,EMBASE,and Web of Science from inception to December 2024.Eligible studies reported GI manifestations in genetic myopathies,including clinical evaluations,imaging,physiological tests,histopathology,and genetic analyses.Inclusion criteria encompassed original research studies,review articles,case reports,and clinical guidelines published in peer-reviewed journals.Exclusion criteria included conference abstracts without full-text availability and non-peer-reviewed sources.Two independent reviewers screened studies and extracted data.They assessed methodological quality using the Newcastle-Ottawa Scale for observational studies,A MeaSurement Tool to Assess Systematic Reviews for systematic reviews,and the Joanna Briggs Institute checklist for case reports.A systematic narrative synthesis was employed to summarize the findings.RESULTS A total of 234 studies met the inclusion criteria.GI manifestations varied widely,with dysphagia,gastroesophageal reflux,abdominal pain,constipation,diarrhea,and fecal incontinence being the most frequently reported symptoms.The included studies highlighted a multidisciplinary diagnostic approach incorporating clinical assessment,imaging,physiological testing,histopathology,and genetic testing.Management strategies ranged from dietary interventions and rehabilitative therapies to pharmacological treatments and surgical procedures.Patient perspectives underscored the significant impact of GI symptoms on quality of life,social interactions,and emotional well-being.The main limitations of the included studies were high heterogeneity in study design,small sample sizes,and the potential risk of bias due to limited methodological rigor in some reports.CONCLUSION This review underscores the complexity of GI manifestations in genetic myopathies and the need for a comprehensive,multidisciplinary management approach.Future research should focus on elucidating molecular mechanisms,identifying biomarkers,and developing targeted therapies to improve patient outcomes.The findings have implications for both clinical practice and public health,emphasizing the necessity of early diagnosis and personalized management strategies.
文摘Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology.
文摘What will our future life be like in China? We classmates imagine our future in China in our class meeting. The results are as follows:Some students think in 2030, our life will be much more colorful, and we can do almost anything(1) on the Internet including seeing a doctor. Most of us think that in 2035。
文摘Hardship The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore whether enduring hardship is still a necessary path to growth in a changing world.
文摘The concept of a community with a shared future for humanity is the core idea of Xi Jinping thought on diplomacy.Since its introduction,this concept has been steadily advanced across various levels and sectors,yielding tangible and meaningful results.Within Chinese academia,the idea of a community with a shared future for humanity,along with the important idea of a maritime community with a shared future,has been integrated into research on South China Sea issues.Scholars have explored China’s approach to establishing regional order in the South China Sea from multiple perspectives,including territorial dispute resolution,maritime rights and interests’protection,environmental conservation,and port cooperation.
文摘From April 8 to 9,2025,the Cent ral Conference on Work Related to Neighboring Countries was held in Beijing.The conference systematically summarized the achievements and experience of China's neighborhood work in the new era,scientifically analyzed the situation,clarified the goals,tasks,ideas,and measures for neighborhood work in the coming period,and emphasized the need to focus on building a community with a shared future with neighboring countries,striving to break new ground in neighborhood work.
文摘As an important part of China's neighborhood,Southeast Asia has always been a high priority in China's neighborhood diplomacy,playing a benchmark and example-setting role in China's drive to build a community with a shared future with neighboring countries.Shortly after the 2025 Central Conference on Work Related to Neighboring Countries,Chinese President Xi Jinping paid state visits to Vietnam,Malaysia,and Cambodia.
文摘February 10-12, Sophia Antipolis, France The ETSI Artificial Intelligence Conference—How Standardization is Shaping the Future of AI will take place faceto-face on February 10-12, 2025, in France.The ETSI AI Conference has been designed to provide attendees with the unique opportunity to exchange with AI subject-experts and learn about the state of the art work that is being done in AI-related standardization, regulation and service deployments.
基金supported by the National Natural Science Foundation of China(Nos.51972198 and 61633015)the Natural Science Foundation of Shandong Province(No.ZR2020JQ19)+1 种基金Taishan Scholars Program of Shandong Province(No.ts20190908)Shenzhen Fundamental Research Program(No.JCYJ20190807093405503).
文摘Sodium-sulfur(Na-S)batteries are considered as a promising successor to the next-generation of high-capacity,low-cost and environmentally friendly sulfur-based battery systems.However,Na-S batteries still suffer from the“shuttle effect”and sluggish ion transport kinetics due to the dissolution of sodium polysulfides and poor conductivity of sulfur.MXenes,as 2D transition metal carbides/nitrides,have exhibited excellent conductivity,diverse structure and tunable surface groups,particularly playing a crucial role in inhibiting polysulfide shuttle and sodium dendrite growth.In this review,achievements and advancements of MXene-based Na-S batteries are discussed,including applications of a sulfur cathode,separator,interlayer between separator and cathode,and sodium anode.In the end,perspectives and challenges on the future development of MXene-based materials in Na-S batteries are proposed.
文摘Mental healthcare in Ethiopia is underutilized due to a lack of resources and skilled practitioners.Psychological counselling offers unique intervention possibilities because of its focus on a wide range of mental health and social justice issues.This literature review tracks the historical development of the profession of psychological counselling in Ethiopia to establish what has been achieved to date and the development challenges.Key achievements include recognition of the profession by the Ministry of Education,growing public awareness,and increasing capacity of practitioners skilled in psychological counselling.Challenges include limited contextually relevant training,poor representation of the profession within Ministry of Health policies,poor public and government mental health literacy,and a lack of regulatory frameworks.Postgraduate training would benefit from more culturally,contextually,and linguistically appropriate evidence-based,indigenous psychology practices.The profession would benefit from engagement in government policy development that promotes mental health,and professional regulatory bodies to hold practitioners accountable to professional standards and ethical practice.
文摘The 2025 Central Conference on Work Related to Neighboring Countries stressed that China's neighborhood is“a vital foundation for achieving development and prosperity,a key front for safeguarding national security,a priority area in managing overall diplomacy,and a crucial link in promoting the building of a community with a shared future for mankind.”
