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Cancer stem cells in hepatocellular carcinoma:platforms,updates,challenges and future perspectives
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作者 Jingyi Lu Diana Chui-Yee O +1 位作者 Yu-Man Tsui Irene Oi-Lin Ng 《Cancer Biology & Medicine》 2026年第1期1-7,共7页
Hepatocellular carcinoma(HCC)is a pressing global health problem and is the sixth most common cancer and the third leading cause of cancer mortality worldwide.Despite continuous advances in treatment modalities,the 5-... Hepatocellular carcinoma(HCC)is a pressing global health problem and is the sixth most common cancer and the third leading cause of cancer mortality worldwide.Despite continuous advances in treatment modalities,the 5-year survival rate is low with a high propensity for recurrence and metastasis1.This clinical challenge in treating HCC is largely attributed to the heterogeneity and intrinsic therapy resistance of cancer stem cells(CSCs),which are a subpopulation of cells with self-renewal capability and multidirectional differentiation potential to induce tumorigenicity2.The behavior and maintenance of CSCs are not autonomous but critically dependent on the complex bidirectional crosstalk between CSCs and the tumor immune microenvironment(TIME)1.In this review we first summarize the recent progress in characterizing CSCs and the interactions between CSCs and the TIME in HCC.Next,we discuss the emerging therapeutic strategies targeting CSC populations with the ongoing challenges.Finally,we give our perspectives on the future directions in HCC CSC research. 展开更多
关键词 future perspectives hepatocellular carcinoma cancer stem cells cscs which cancer stem cells CHALLENGES therapeutic strategies hepatocellular carcinoma hcc tumor immune microenvironment
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Laparoendoscopic surgery in gastrointestinal diseases:Status and future perspectives
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作者 Kush Satyen Parikh Payal Kaw Ashok Kumar 《World Journal of Gastrointestinal Endoscopy》 2025年第8期28-39,共12页
Laparoscopic and endoscopic cooperative surgery(LECS)is a hybrid minimally invasive technique originally developed for treatment of gastric submucosal tumors.Several modifications of LECS—including inverted LECS,non-... Laparoscopic and endoscopic cooperative surgery(LECS)is a hybrid minimally invasive technique originally developed for treatment of gastric submucosal tumors.Several modifications of LECS—including inverted LECS,non-exposed endoscopic wall-inversion surgery,and closed LECS have evolved over a period of time to address the earlier concerns about peritoneal contamination and tumor seeding.These innovations have led to the application of combined laparoendoscopic techniques to several gastrointestinal(GI)lesions such as the duodenum,colon,and rectum.This minireview explores the evolution,current applications,and future potential of laparoendoscopic surgery in GI diseases. 展开更多
关键词 Laparoscopic surgery Endoscopic surgery Laparoscopic and endoscopic cooperative surgery Gastrointestinal diseases Current status future perspective
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New era towards autonomous additive manufacturing:a review of recent trends and future perspectives
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作者 Haolin Fan Chenshu Liu +10 位作者 Shijie Bian Changyu Ma Junlin Huang Xuan Liu Marshall Doyle Thomas Lu Edward Chow Lianyi Chen Jerry Ying Hsi Fuh Wen Feng Lu Bingbing Li 《International Journal of Extreme Manufacturing》 2025年第3期183-230,共48页
The additive manufacturing(AM)landscape has significantly transformed in alignment with Industry 4.0 principles,primarily driven by the integration of artificial intelligence(AI)and digital twins(DT).However,current i... The additive manufacturing(AM)landscape has significantly transformed in alignment with Industry 4.0 principles,primarily driven by the integration of artificial intelligence(AI)and digital twins(DT).However,current intelligent AM(IAM)systems face limitations such as fragmented AI tool usage and suboptimal human-machine interaction.This paper reviews existing IAM solutions,emphasizing control,monitoring,process autonomy,and end-to-end integration,and identifies key limitations,such as the absence of a high-level controller for global decision-making.To address these gaps,we propose a transition from IAM to autonomous AM,featuring a hierarchical framework with four integrated layers:knowledge,generative solution,operational,and cognitive.In the cognitive layer,AI agents notably enable machines to independently observe,analyze,plan,and execute operations that traditionally require human intervention.These capabilities streamline production processes and expand the possibilities for innovation,particularly in sectors like in-space manufacturing.Additionally,this paper discusses the role of AI in self-optimization and lifelong learning,positing that the future of AM will be characterized by a symbiotic relationship between human expertise and advanced autonomy,fostering a more adaptive,resilient manufacturing ecosystem. 展开更多
关键词 future manufacturing autonomous additive manufacturing artificial intelligence agent large multimodal models knowledge graphs
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Call for Papers from Journal of Future Foods
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《肉类研究》 北大核心 2026年第4期I0012-I0012,共1页
Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belongi... Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Sciences.Production and Hosting:Elsevier B.V.on behalf of KeAi Communications Co.,Ltd.)is an international,peer-reviewed open access journal belonging to the discipline of food science and technology.The aim of the journal is to report latest research results of high-tech in food science.We welcome submissions that drive the field of food science towards whole food nutrition,intelligence and high technology. 展开更多
关键词 Journal of future Foods
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Call for Papers from Journal of Future Foods
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《食品科学》 北大核心 2026年第2期I0027-I0027,共1页
Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Scicnces.Production and Hosting:Elsevier B.V.on bchalf of KeAi Communications Co.,Ltd)is an international,peer reviewed open access joumal belonging... Journal of Future Foods(ISSN 2772-5669.Owner:Beijing Academy of Food Scicnces.Production and Hosting:Elsevier B.V.on bchalf of KeAi Communications Co.,Ltd)is an international,peer reviewed open access joumal belonging to the discipline of food science and technology.The aim of the joumal is to report latest research results of high-tech in food science.We welcone submissions that drive the ficld of food scicnce towards whole food nutrition,intelligence and high technology. 展开更多
关键词 high technology open access ficld food scicnce JOURNAL whole food nutrition technology future foods food science
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The youth sail for their future career through joining the competition
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作者 Fang Luofan 《China Standardization》 2026年第1期52-53,共2页
During the final of the International Standardization Youth Star Competition 2025,China Standardization interviewed several teams.In these young students,we see stories of their exploration,perseverance and dreams.The... During the final of the International Standardization Youth Star Competition 2025,China Standardization interviewed several teams.In these young students,we see stories of their exploration,perseverance and dreams.The competition has come to an end,but the real journey has just begun:How will this experience change their future pursuit? 展开更多
关键词 CAREER exploration future standardization COMPETITION dreams PERSEVERANCE YOUTH
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Fueling the Future: AAetok’s New Road to Openness
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作者 Xu Lindi(Text/Photos) Zhang Xu(Text/Photos) +1 位作者 Li Yilei(Text/Photos) Li Nan(Translated) 《China's Tibet》 2026年第1期29-35,共7页
Metok,located in Nyingchi,the Xizang Autonomous Region,is known as the last county in China to be connected by road.Poor transportation and limited access to petroleum were two obstacles to its development.As soon as ... Metok,located in Nyingchi,the Xizang Autonomous Region,is known as the last county in China to be connected by road.Poor transportation and limited access to petroleum were two obstacles to its development.As soon as the highway connecting Metok and the outside world was completed in 2014,China National Petroleum Corporation’s(CNPC)first gas station in the county was put into operation,providing the momentum for this"secret land of Lotus"and helping it embark on a journey toward openness and prosperity. 展开更多
关键词 Metok ROAD Nyingchi future OPENNESS FUELING gas station Xizang
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China-Laos Relations in the New Era of Building a Community with a Shared Future Congratulatory message from Chinese Ambassador to Laos Fang Hong on the 65th anniversary of the establishment of diplomatic relations between China and Laos
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《China Report ASEAN》 2026年第1期18-18,共1页
On the occasion of the 65th anniversary of the establishment of diplomatic relations between China and Laos,I wish to express,on behalf of the Embassy of the People's Republic of China in the Lao People's Demo... On the occasion of the 65th anniversary of the establishment of diplomatic relations between China and Laos,I wish to express,on behalf of the Embassy of the People's Republic of China in the Lao People's Democratic Republic,our sincere gratitude and highest respect to all friends and personages from various sectors in both countries who have long cared about and supported the development of our bilateral relations. 展开更多
关键词 ANNIVERSARY diplomatic relations China Laos community shared future
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The Relationship between Peer Victimization and Non-Suicidal Self-Injury Behavior among Middle School Students:The Mediating Role of Future Orientation and Social Withdrawal
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作者 Biao Li Xiao Hu +1 位作者 Pengzhan Wei Yunbin Deng 《International Journal of Mental Health Promotion》 2026年第2期157-170,共14页
Objectives:Non-suicidal self-injury(NSSI)represents a prominent and escalating concern within mental health,associated with considerable psychological and physical dangers.Peer victimization is identified as a signifi... Objectives:Non-suicidal self-injury(NSSI)represents a prominent and escalating concern within mental health,associated with considerable psychological and physical dangers.Peer victimization is identified as a significant predictor of NSSI behavior.Although prior research has explored the association between peer victimization and NSSI,the mechanisms underlying this relationship remain insufficiently understood.Utilizing social information processing theory frameworks,the present study seeks to examine the sequential mediating roles of a cognitive factor,future orientation,and a behavioral factor,social withdrawal,in middle school students.Methods:A cross-sectional survey was administered in China,involving 528 participants(261 females and 267 males;Meanage=13.71,standard deviation[SD]=0.93).Participants completed self-report measures assessing peer victimization via the Delaware Bullying Victimization Scale-Student Version,NSSI via the Adolescents Self-Harm Scale,future orientation via the Adolescent Future Orientation Questionnaire,and social withdrawal via the Social Withdrawal Questionnaire.Results:Findings indicated a significant positive correlation between peer victimization and NSSI(r=0.30,p<0.01).Additionally,future orientation and social withdrawal functioned as serial mediators,with an indirect effect of 0.01(95%CI:[0.01,0.02]),representing 2.70%of the total effect(𝛽=0.37,95%CI:[0.25,0.47]).Conclusions:The findings endorse a theoretical framework in which negative future outlook and social withdrawal are sequentially linked within the relationship between peer victimization and NSSI.Although the serial indirect effect observed is modest,it delineates a distinct associative pattern that characterizes adolescents subjected to victimization.These results carry practical significance for school-based intervention programs,indicating that targeting future perspectives and social connections may enhance strategies for preventing NSSI. 展开更多
关键词 Peer victimization non-suicidal self-injurious future orientation social withdrawal
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Asia Pacific Hope for a Sustainable Future
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作者 James D.Sellmann 《Philosophy Study》 2026年第1期45-57,共13页
This paper expands Prasenjit Duara’s proposal that Asian religions and philosophies offer hope for a sustainable future.After outlining Duara’s sociology of history that describes the crisis of global modernity in t... This paper expands Prasenjit Duara’s proposal that Asian religions and philosophies offer hope for a sustainable future.After outlining Duara’s sociology of history that describes the crisis of global modernity in terms of three global changes,namely the rise of non-western nations,the crisis of climate change,and the decline of religious or transcendent sources of authority,Duara proposes that grassroots organizations coupled with Asian religious and philosophical beliefs and practices offer different ways of understanding the relationship between the person and the environment,and between our universal-planetary interests and our national interests.Drawing from Asian and Pacific indigenous teachings,I propose a type of depth ecology called“existential parity”that all things and creatures have value,generating a moral corollary called the“existential commitment”that humans take responsibility for the environment and each other.The existential commitment offers an environmental ethics that promotes sustainable agriculture to feed the world’s population.Pacific agroforestry practices can be implemented in urban settings to help mitigate climate change and food shortages. 展开更多
关键词 depth ecology AGROFORESTRY Asia Pacific food ethics sustainable future
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Standards help shape the future responsibly
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作者 Erik Vladimir Simic 《China Standardization》 2026年第1期50-51,共2页
I come from Slovenia,a small but ambitious country from Central Europe.I study at the Faculty of Electrical Engineering at the University of Ljublgana.I have the privilege of being one of the first young ambassadors o... I come from Slovenia,a small but ambitious country from Central Europe.I study at the Faculty of Electrical Engineering at the University of Ljublgana.I have the privilege of being one of the first young ambassadors of standardization not only in Slovenia but of this generation across the entire world. 展开更多
关键词 STANDARDS UNIVERSITY RESPONSIBILITY electrical engineering young ambassadors future slovenia central europe
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New Journey Toward a China-Laos Community with a Shared Future Exclusive interview with Deputy Minister of Foreign Affairs of Laos Phongsavanh Sisoulath
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作者 Guo Xixian 《China Report ASEAN》 2026年第1期19-21,共3页
The year 2026 marks the 65th anniversary of the establishment of diplomatic relations between China and Laos.The bilateral relations are now at a new starting point where the past has been inherited and a course for t... The year 2026 marks the 65th anniversary of the establishment of diplomatic relations between China and Laos.The bilateral relations are now at a new starting point where the past has been inherited and a course for the future has been set.Looking back,China and Laos have weathered storms together and stood by each other. 展开更多
关键词 shared future diplomatic relations ANNIVERSARY cooperation bilateral relations China establishment diplomatic relations Laos
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The Electric Wave:Battery-powered vessels and smart systems are directing China’s rivers towards a sustainable future
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作者 GE LIJUN 《ChinAfrica》 2026年第2期49-51,共3页
Each morning at Yangluo Port in Wuhan,Hubei Province,the all-electric cargo vessel Huahang Xinneng No.1 completes a battery swap in under 10 minutes before returning to service with nearly 8,000 kWh of power onboard。
关键词 yangluo port china WUHAN battery swap battery powered vessels sustainable future smart systems electric waves
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SEEKING SHARED PROSPERITY Dialogue on Building a China-Laos Community with a Shared Future held in Vientiane
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作者 Gao Yuan 《China Report ASEAN》 2026年第3期46-47,共2页
On February 5, the Dialogue on Building a China-Laos Community with a Shared Future, themed “Focusing on the ‘Action Plan,’ Creating a Better Future Together,” took place in Vientiane, Laos.The opening ceremony fe... On February 5, the Dialogue on Building a China-Laos Community with a Shared Future, themed “Focusing on the ‘Action Plan,’ Creating a Better Future Together,” took place in Vientiane, Laos.The opening ceremony featured speeches by several distinguished vips including Fang Hong, Chinese ambassador to Laos, Daosavanh Kheugmixai, vice president of the Lao National Academy of Politics and Public Administration, Yu Yunquan, vice president of the China International Communications Group (CICG),Sakhon Phommalat, deputy head of the Propaganda and Training Board of the Lao People’s Revolutionary Party (LPRP) Central Committee, Sun Jisheng, vice president of China Foreign Affairs University (CFAU),and Vadthuninyom Duangmala,president of the Diplomatic Academy of Laos. 展开更多
关键词 shared future action plan shared prosperity DIALOGUE china international communications group china laos community
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The Diplomatic Power of Proverbs--Xi Jinping’s African discourse harmonises Chinese and African wisdom and boosts the construction of a China-Africa community with a shared future
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作者 ETIENNE BANKUWIHA 《ChinAfrica》 2026年第1期23-25,共3页
As a Burundian doctoral student at Nanjing University,my personal journey is closely intertwined with China’s development in the new era and the deepening China-Africa partnership.Recently,my experiences have given m... As a Burundian doctoral student at Nanjing University,my personal journey is closely intertwined with China’s development in the new era and the deepening China-Africa partnership.Recently,my experiences have given me a deeper appreciation of the importance of people-to-people exchanges between China and Africa. 展开更多
关键词 shared future china africa community diplomatic power african wisdom african discourse chinese wisdom proverbs xi jinping
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Pioneering a Shared Future China-Laos ties under a new blueprint
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作者 Guo Yanjun Li Zhengyang 《China Report ASEAN》 2026年第1期22-25,共4页
As China and Laos mark the 65th anniversary of their diplomatic relations,the two socialist neighbors stand at a new historical starting point.From revolutionary comrades-in-arms to comprehensive strategic partners,Ch... As China and Laos mark the 65th anniversary of their diplomatic relations,the two socialist neighbors stand at a new historical starting point.From revolutionary comrades-in-arms to comprehensive strategic partners,China and Laos have steadily deepened their bond as"good neighbors,good friends,good comrades,and good partners." 展开更多
关键词 shared future diplomatic relations good neighbors China good friends socialist neighbors comprehensive strategic partners good comrades
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Growing a Rural Future--A young Ugandan channels insights from China’s model villages to build a more resilient,cooperative and forward-looking Busoga
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作者 LI XIAOYU 《ChinAfrica》 2026年第1期56-57,共2页
In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with t... In the lush heart of Uganda’s Busoga sub-region,Isaac Imaka is charting a new course for rural development.After seven years in national media,he left the newsroom and stepped into the soil.The former reporter with the Daily Monitor was driven by the belief that communities like his in Jinja North deserved more than chronic poverty and hand-to-mouth survival. 展开更多
关键词 community resilience Uganda rural development model villages rural future Busoga sub region cooperative development rural journalism
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Towards a Cooperative Global Future——China’s Global Governance Initiative lays emphasis on concrete actions aimed at promoting peace and development rather than on symbolic declarations
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作者 BUSANI NGCAWENI 《ChinAfrica》 2026年第2期16-17,共2页
As we enter the year 2026,the international system continues to receive shocks from Donald Trump,arguably the 21st century’s most disruptive US leader.His return to the White House in 2025 coincided with the 80th ann... As we enter the year 2026,the international system continues to receive shocks from Donald Trump,arguably the 21st century’s most disruptive US leader.His return to the White House in 2025 coincided with the 80th anniversary of the defeat of fascism and the establishment of the United Nations,the multilateral platform that carried the world’s hope for peace,restraint and collective security.The coincidence was unsettling.A world order designed to limit power now confronts a moment in which power is exercised openly,transactionally and unapologetically. 展开更多
关键词 multilateral platform cooperative global future development Donald Trump united nationsthe PEACE Chinas global governance initiative symbolic declarations
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Navigating physical activity research in complex terrains:Reflections on the challenges,opportunities,and future directions
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作者 Ding Ding 《Journal of Sport and Health Science》 2026年第3期3-5,共3页
In 2025,I had the honor of delivering keynote speeches at the conferences of the International Society for Diet and Activity Methods in Toronto,Canada,and the International Society of Behavioural Nutrition and Physica... In 2025,I had the honor of delivering keynote speeches at the conferences of the International Society for Diet and Activity Methods in Toronto,Canada,and the International Society of Behavioural Nutrition and Physical Activity in Auckland,Aotearoa,New Zealand.These opportunities prompted deep reflection on scientific research in general,and on physical activity and health research specifically. 展开更多
关键词 scientific research complex terrains future directions diet activity methods research challenges physical activity behavioural nutrition physical activity
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HANDS ACROSS THE SEA“Forward Together”Dialogue on Building Brunei-China Community with a Shared Future held in Brunei
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作者 Zhu Mengxiao 《China Report ASEAN》 2026年第3期50-51,共2页
The“Forward Together”Dialogue on Building a China-Brunei Community with a Shared Future was held on the morning of February 7 at Universiti Brunei Darussalam(UBD)in Bandar Seri Begawan.Scheduled for the lead-up to t... The“Forward Together”Dialogue on Building a China-Brunei Community with a Shared Future was held on the morning of February 7 at Universiti Brunei Darussalam(UBD)in Bandar Seri Begawan.Scheduled for the lead-up to the 35th anniversary of diplomatic relations between China and Brunei in 2026,the event aimed to deepen strategic mutual trust,build broader consensus on cooperation,and generate both intellectual momentum and practical proposals for advancing a closer China-Brunei community with a shared future. 展开更多
关键词 shared future forward together cooperation DIALOGUE universiti brunei darussalam ubd momentum practical proposals strategic mutual trust deepen strategic mutual trustbuild
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