In this paper,the authors construct a class of fractal surfaces,Bush type surfaces,based on the Bush type functions.The Box dimension,Packing dimension and Hausdorff dimension of such surfaces are investigated.
Severe fever with thrombocytopenia syndrome(SFTS)is an emerging infectious disease with high mortality(12%–30%).The mechanism by which the SFTS bunyavirus(SFTSV)causes severe illness remains unclear.To evaluate the p...Severe fever with thrombocytopenia syndrome(SFTS)is an emerging infectious disease with high mortality(12%–30%).The mechanism by which the SFTS bunyavirus(SFTSV)causes severe illness remains unclear.To evaluate the phenotypic and functional characteristics of the NK cell subsets in SFTS patients,twenty-nine SFTS patients were sequentially sampled from admission until recovery.Phenotypic and functional characteristics of NK cell subsets in circulating blood were analysed via flow cytometry.Then,correlations between NK cell subset frequencies and the SFTS index(SFTSI)were evaluated in all SFTS patients(15 mild,14 severe)upon admission.The frequencies of CD56dimCD16+NK cells were greatly decreased in early SFTSV infection and were negatively correlated with disease severity.Additionally,higher Ki-67 and granzyme B expression and relatively lower NKG2 A expression in CD56dimCD16+NK cells were observed in acute infection.Moreover,the effector function of CD56dimNK cells was increased in the acute phase compared with the recovery phase in nine severe SFTS patients.Additionally,interleukin(IL)-15,interferon(IFN)-a,IL-18 and IFN-c secretion was markedly increased during early infection.Collectively,despite depletion of CD56dimCD16+NK cells,activation and functional enhancement of CD56dimCD16+NK cells were still observed,suggesting their involvement in defence against early SFTSV infection.展开更多
Local dimming(区域背光调控)是改善被动发光的液晶显示器性能的重要技术。采用一套自主开发的仿真算法,在充分验证其准确性后,对液晶显示器的对比度和光晕指数随分区数的变化关系进行了计算仿真与分析,最终形成背光分区数设计指引。分...Local dimming(区域背光调控)是改善被动发光的液晶显示器性能的重要技术。采用一套自主开发的仿真算法,在充分验证其准确性后,对液晶显示器的对比度和光晕指数随分区数的变化关系进行了计算仿真与分析,最终形成背光分区数设计指引。分析结果表明:对比度随分区数的增加而增加,RTINGS棋盘格图片最大价值点(导数为1的点)为300分区,要达到足够接近最大对比度,则需要1600分区左右;背光行列分区数为8的倍数时有更好的对比度体现;光晕指数与对比度随分区数变化的趋势相似,RTINGS十字架图片最大价值点(导数为1)为500分区。展开更多
文摘In this paper,the authors construct a class of fractal surfaces,Bush type surfaces,based on the Bush type functions.The Box dimension,Packing dimension and Hausdorff dimension of such surfaces are investigated.
基金supported by the National Natural Science Foundation of China(81271884)and of Hubei(2018CFB471)
文摘Severe fever with thrombocytopenia syndrome(SFTS)is an emerging infectious disease with high mortality(12%–30%).The mechanism by which the SFTS bunyavirus(SFTSV)causes severe illness remains unclear.To evaluate the phenotypic and functional characteristics of the NK cell subsets in SFTS patients,twenty-nine SFTS patients were sequentially sampled from admission until recovery.Phenotypic and functional characteristics of NK cell subsets in circulating blood were analysed via flow cytometry.Then,correlations between NK cell subset frequencies and the SFTS index(SFTSI)were evaluated in all SFTS patients(15 mild,14 severe)upon admission.The frequencies of CD56dimCD16+NK cells were greatly decreased in early SFTSV infection and were negatively correlated with disease severity.Additionally,higher Ki-67 and granzyme B expression and relatively lower NKG2 A expression in CD56dimCD16+NK cells were observed in acute infection.Moreover,the effector function of CD56dimNK cells was increased in the acute phase compared with the recovery phase in nine severe SFTS patients.Additionally,interleukin(IL)-15,interferon(IFN)-a,IL-18 and IFN-c secretion was markedly increased during early infection.Collectively,despite depletion of CD56dimCD16+NK cells,activation and functional enhancement of CD56dimCD16+NK cells were still observed,suggesting their involvement in defence against early SFTSV infection.
