China is one of the countries with the longest history in the world.The protection and development of historical and cultural resources is an issue worthy of attention in the fields of economic geography and urban-rur...China is one of the countries with the longest history in the world.The protection and development of historical and cultural resources is an issue worthy of attention in the fields of economic geography and urban-rural planning at the present stage.This study takes the Zhongyuan Urban Agglomeration,which is rich in historical and cultural heritage,as a specific case,analyzes the characteristics of the spatial-temporal distribution pattern of its historical and cultural resources.The results show that the distribution structure of historical and cultural element resources within the Zhongyuan Urban Agglomeration presents significant regional agglomeration and combination characteristics.In response to the analysis results,the study formulates an optimization strategy for the regional development pattern supported by the protection and development of historical and cultural resources,and initially proposes a matching spatial development pattern plan and policy recommendations for coordinated development.展开更多
Global industrial chains(GICs)have become a hallmark of the world economy underpinning the global production cycle.Since the reform and opening up was introduced in 1978,China has taken an active role in global value ...Global industrial chains(GICs)have become a hallmark of the world economy underpinning the global production cycle.Since the reform and opening up was introduced in 1978,China has taken an active role in global value chains(GVCs)and become the world’s factory floor.Under the external shocks to GICs,such as US trade frictions with China and the COVID-19 pandemic,China’s traditional comparative advantages in manufacturing which include its labor force and costs are waning.This has manifested in a wave of industrial relocations from China to other countries as well as China’s weakening international competitiveness.We took stock of the concepts and journey of GVCs and elaborated the intrinsic relationship between GVCs and the new development pattern of“dual circulations”.We also analyzed the trends of GVCs,the current status and problems of China’s industrial chains,and China’s market heft,complete industrial chains and the digital economy as new strengths for industrial chain upgrade.In our conclusion,this paper put forth some policy recommendations for China’s industrial chain upgrade in the context of dual circulations.展开更多
The development pattern, development situation, and existing problems of land exploitation in Zigui County, Three Gorges Reservoir Areas of China were presented. The sustainable development mode and its strategy in th...The development pattern, development situation, and existing problems of land exploitation in Zigui County, Three Gorges Reservoir Areas of China were presented. The sustainable development mode and its strategy in the Three Gorges Reservoir Areas was also discussed. A sustainable development framework for low mountain regions, middle mountain regions and high mountain regions was developed, and management countermeasures for structural optimization of complex ecosystems were advanced.展开更多
The study profiles and explains the significant changes that have taken place in China's spatial development patterns since the inception of its economic reform and opening two decades ago. Principal component an...The study profiles and explains the significant changes that have taken place in China's spatial development patterns since the inception of its economic reform and opening two decades ago. Principal component analysis is used to delineate spatial patterns. The analyses show that prior to the reform China's spatial development pattern was characterized by the dominance of the three municipalities and the Northeast, as well as by both the coast-interior and the north-south disparities. Northern provinces were generally more industrialized and economically powerful than the southern ones. After two decades of reform, regional development has become multi-centered with South China, the Yangtze Delta and the Beijing-Tianjin area being the three most important regions of the country. The coastal provinces as a whole rose to prominence on China's economic map while the Northeast has diminished its clout. The coast-interior gap not only remains but may have widened. The north-south disparity also still exists but there has been a role reversal with the south now in the lead position. Virtually all inland provinces now find themselves at or near the low end of the development spectrum. We argue that the major reason for the recent shifts in Chinese space economy is the spatially differentiated economic growth resulted from the reform and open door policy and from the new, uneven development strategy adopted by the Chinese government. The paper discusses four specific factors that have reshaped China's spatial development patterns.展开更多
"Three new developments"is the guiding ideology of Chinese-style high-quality development in the new era.Jujube(Zizyphus jujube Mill.)is a plant of Zizyphus of Rhamnaceae,which originated in China and has be..."Three new developments"is the guiding ideology of Chinese-style high-quality development in the new era.Jujube(Zizyphus jujube Mill.)is a plant of Zizyphus of Rhamnaceae,which originated in China and has been listed as one of the"five fruits"since ancient times.Xinjiang is the most important jujube producing area in China,and its yield has accounted for 50%of the national jujube yield.In the five prefectures and cities of southern Xinjiang,as well as the regimental farms of southern and eastern Xinjiang of Xinjiang Production and Construction Corps,the jujube industry is an advantageous characteristic industry in agriculture.This paper studied Xinjiang jujube industry and its agricultural intellectual property resources,analyzed six major issues to be further implemented,such as the"three new developments"thinking and the strategy of building an intellectual property power,and puts forward eight strategies such as coordinating the two markets and two resources to accelerate the construction of a new development pattern and dual circulation of jujube.展开更多
This paper examines China’s flying geese paradigm that serves as a key driver of a new pattern of the country’s economic development.Our results suggest that such a major power’s flying geese paradigm has taken sha...This paper examines China’s flying geese paradigm that serves as a key driver of a new pattern of the country’s economic development.Our results suggest that such a major power’s flying geese paradigm has taken shape in the aftermath of the global financial crisis in 2008.However,this paradigm has provincial heterogeneity in that industrial relocation varies across provinces.For instance,China’s central and western regions have shown differences while serving as destinations for labor-intensive industries and processing trade.This flying geese paradigm evolves in a slow and nonlinear manner,and may be subject to stagnation and even reversal.展开更多
On the way to the construction of new countryside, Henan province has been exploring its own new construction development pattern actively. This paper analyzes the four development patterns-Xingyang mode, Zhongmou mod...On the way to the construction of new countryside, Henan province has been exploring its own new construction development pattern actively. This paper analyzes the four development patterns-Xingyang mode, Zhongmou mode,Xinmi mode and Gongyi mode --from the perspective of ecological civilization development on the basis of sufficient data and extensive research. This also concludes their experience to realize the sustainable development of the new construction of new countryside.展开更多
In coping with the global financial crisis, all levels of the Chinese government and foreign trade firms have not only created new practices but have also changed their goal from transforming the growth pattern of for...In coping with the global financial crisis, all levels of the Chinese government and foreign trade firms have not only created new practices but have also changed their goal from transforming the growth pattern of foreign trade to transforming the development pattern of joreign trade. China＇s experience shows that economic instruments such as Net Barter Terms of Trade （NBTT） and the smile curve theory have limitations when it comes to interpreting foreign trade. If used improperly, scientific theories often lead to.fallacies. Transjbrming the development pattern of China＇s .foreign trade requires the following changes： national income distribution, foreign trade competition, market exploration, and resource utilization. We advise that competent authorities create a reasonable and operational system of assessment indicators.展开更多
Taking rural sports development model in Xvchang as the research object, the article has given an investigation on status of rural sports development in Xvchang with the literature material method, interviewing method...Taking rural sports development model in Xvchang as the research object, the article has given an investigation on status of rural sports development in Xvchang with the literature material method, interviewing method, questionnaire survey, and analyzed the influential factors to offer the development pattern, which also provides reference for the rapid development of new rural sports and the relevant departments to formulate corresponding policies.展开更多
The urban construction of Shanghai will come into a new area since China has deciared to exploit and open Pudong. Based on the analysis on economic development of China and the world, the developmental strategy for Sh...The urban construction of Shanghai will come into a new area since China has deciared to exploit and open Pudong. Based on the analysis on economic development of China and the world, the developmental strategy for Shanghai should take the following contents into consideration: 1) Shanghai should be built into one of the most important intemational and modern supercity in Asian-Pacifie Region. 2) Shanghai should keep the position of the largest economic center of China and important port city for international trade. 3) Shanghai should be taken as growth pole of the Changjiang River Delta. According to the considderations mentioned above, the spatial distribution patten and the management of environment are discassed.展开更多
China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in...China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in poverty elimination,there is a lack of quantitative studies categorizing and comparing poverty-elimination counties(PECs)based on their processes.This study proposes an innovative framework for analyzing PECs’development paths from the perspective of population-land-industry(PLI).We quantify the PLI matching degree of PECs in China during the critical phase of the battle against poverty through a multivariate matching model,classify PECs via K-means clustering according to the consistency in PLI matching degree evolution,and summarize the typical development patterns of PECs.Results indicate that the PLI matching degree of PECs in China increased substantially from 2015 to 2020,particularly in eastern areas,while the western region,including the Qinghai-Xizang Plateau and southwestern Xinjiang,shows untapped potential for improvement.Five types of PECs are identified,with the majority(30.1%)showing sustained moderate PLI matching and a minority(9.6%)experiencing long-term PLI mismatch.Industry is the shortfall of various PECs,and effective strategies to facilitate all types of PECs include the development of emerging businesses and the expansion of secondary and tertiary industries.Additionally,enriching rural labor force and increasing farmland use efficiency are essential for optimal PLI matching and positive interaction,ultimately ensuring poverty elimination and sustainable development.展开更多
Beginning with increasing effective demand,thedemand-sidereformadvocates for the strategy to expand domestic demand,rectifies distortions in the demand structure,and further aligns demand and supply by reforming the m...Beginning with increasing effective demand,thedemand-sidereformadvocates for the strategy to expand domestic demand,rectifies distortions in the demand structure,and further aligns demand and supply by reforming the mechanisms for demand formation and regulation,matching supply and demand structures,and easing restrictions on demand.This will enhance economic growth potential and operational efficiency.The demandside reform contributes to developing a super-large-scale market and optimize market functions to form a unified national market.It also helps address significant structural distortions within domestic circulation and move faster to form a new development pattern of dual circulation.As demand-side reform inevitably deals with the vested interests of stakeholders,it presents challenges on par with supplyside structural reform.Therefore,due attention must be given in terms of priority and weight by increasing operational and property household income,transforming governmentt functions,rectifying any excessive market-orientedreforms in certain public service sectors,among others.展开更多
In recent years,the changes in the external environment and domestic development conditions have promoted the transformation of China's economy to one dominated by domestic circulation.In December 2020,the Communi...In recent years,the changes in the external environment and domestic development conditions have promoted the transformation of China's economy to one dominated by domestic circulation.In December 2020,the Communist Party of China Central Committee put forward the demand-side reform for the first time in order to prepare China for the new development stage of the 14th Five-Year Plan(2021-2025)and to promote the new strategic deployment of China's high-quality development.Based on the paths and direction of the current 14thFive-YearPlan(2021-2015)tobuild a new development pattern,this paper elaborates on the theoretical connotations of the demand-side reform,points out the bottlenecks such as the unreasonable demand structure in China,the mismatch between the industrial system and the high-level demand,the resulting demand spillovers,the poor demand channels,and puts forward the current approaches to thedemand-sideereform in China.展开更多
Considering some advantages of Rana nigromaculata as an experimental species, we propose that this species, like Xenopus laevis, could be used to assay thyroid hormone（TH） signaling disrupting actions. To validate t...Considering some advantages of Rana nigromaculata as an experimental species, we propose that this species, like Xenopus laevis, could be used to assay thyroid hormone（TH） signaling disrupting actions. To validate the utilizability of R. nigromaculata, we investigated the responsiveness of R. nigromaculata to a TH receptor（TR） agonist（T3） and antagonist（amiodarone） by analyzing expression, based on characterizing TR cDNA and developmental expression patterns. With high levels of identity with the corresponding genes in X. laevis, both TRα and TRβ in R. nigromaculata exhibited roughly similar developmental expression patterns to those of X. laevis, in spite of some species-specific differences. Both TRα and TRβ expression had greater changes in the liver and intestine than in the tail and brain during metamorphosis. T3 exposure for 2 days induced more dramatic increases of TRβ expression in stage 27 than in stage34 tadpoles but not in stage 42 tadpoles, showing that the responsiveness of R. nigromaculata to TH decreased with development and disappeared at the onset of metamorphic climax.Corresponding to greater changes of TRβ expression in the liver and intestine than in the tail and brain during metamorphosis, the liver and intestine had higher responsiveness to exogenous T3 than the tail and brain. Amiodarone inhibited T3-induced TRβ expression. Our results show that R. nigromaculata can be used as a model species for assaying TH signaling disrupting actions by analyzing TRβ expression, and intestine tissues at stage 27 are ideal test materials due to high responsiveness and easy accessibility.展开更多
The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Prov...The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Province and tried to find the generation mechanisms of current non-balanced economic development of Shandong Province.And then approaches to regional development were put forward according to the theory of regional development pattern as a whole.展开更多
Foeused on the lack of proper organization for patterns in the development of pattern based software, a POMSDP model with layered tree structure for organizing patterns during the process of development was put torwar...Foeused on the lack of proper organization for patterns in the development of pattern based software, a POMSDP model with layered tree structure for organizing patterns during the process of development was put torward. The model and its interrelated eoneepts were strictly defined and introduced by applying the theory of set, symbolie logic and pattern, which ensures the correctness, maturity and expansibility of the model. The expansibility of the model was discussed mainly. The basic realization and the application in the automatic query system were presented. Based on the existing software development methods, the POMSDP model resolves the problem of chaos in the application of patterns, strengthens the controllability of the system, and facilitates the improvement, maintenance, expansion, and especially the reengineering of the software system.展开更多
Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncert...Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncertainty.The fact that the Ukrainian Crisis has dragged on for long and that展开更多
Consumption pattern of beta carotene rich foods from 500 households of Coimbatore district was elicited. Through market surveys in four seasons namely: summer, south-west monsoon, north-east monsoon and winter, a year...Consumption pattern of beta carotene rich foods from 500 households of Coimbatore district was elicited. Through market surveys in four seasons namely: summer, south-west monsoon, north-east monsoon and winter, a year calendar of beta carotene rich foods was developed. The total and beta carotene contents of five commonly consumed beta carotene rich foods both in raw and cooked states were determined. Results indicated that greens were mainly purchased from market and consumed 2-3 times per week. Cooking loss was maximum in boiling and minimum in shallow fat frying. Curry leaves (Murraya koenigii),amaranth tender (Amaranthus gangeticus), agathi (Sesbania grandopra), and ponnanganni (Alternanthera sessilis) were the carotene rich foods available round the year. Cost of most greens was highest in summer and lowest in north-east monsoon. Within a cost of 13-14 ps in summer, 4-10 ps in south-west monsoon and north-west monsoon and 4-12 ps in winter season, the entire day's requirement of beta carotene (2400μg) could be obtained in the form of agathi/amaranth throughout the year: in the form of drumstick leaves and mint in south-west monsoon; as curry leaves and coriander leaves in winter and as agathi,paruppukeerai and amaranth in summer. From this year calendar, according to seasonal availability and cost, low-cost high carotene foods can be selected and used for increasing the beta carotene intake in the intervention programmes and in the community展开更多
基金Major Program of National Fund of Philosophy and Social Science of China(24&ZD148).
文摘China is one of the countries with the longest history in the world.The protection and development of historical and cultural resources is an issue worthy of attention in the fields of economic geography and urban-rural planning at the present stage.This study takes the Zhongyuan Urban Agglomeration,which is rich in historical and cultural heritage,as a specific case,analyzes the characteristics of the spatial-temporal distribution pattern of its historical and cultural resources.The results show that the distribution structure of historical and cultural element resources within the Zhongyuan Urban Agglomeration presents significant regional agglomeration and combination characteristics.In response to the analysis results,the study formulates an optimization strategy for the regional development pattern supported by the protection and development of historical and cultural resources,and initially proposes a matching spatial development pattern plan and policy recommendations for coordinated development.
文摘Global industrial chains(GICs)have become a hallmark of the world economy underpinning the global production cycle.Since the reform and opening up was introduced in 1978,China has taken an active role in global value chains(GVCs)and become the world’s factory floor.Under the external shocks to GICs,such as US trade frictions with China and the COVID-19 pandemic,China’s traditional comparative advantages in manufacturing which include its labor force and costs are waning.This has manifested in a wave of industrial relocations from China to other countries as well as China’s weakening international competitiveness.We took stock of the concepts and journey of GVCs and elaborated the intrinsic relationship between GVCs and the new development pattern of“dual circulations”.We also analyzed the trends of GVCs,the current status and problems of China’s industrial chains,and China’s market heft,complete industrial chains and the digital economy as new strengths for industrial chain upgrade.In our conclusion,this paper put forth some policy recommendations for China’s industrial chain upgrade in the context of dual circulations.
文摘The development pattern, development situation, and existing problems of land exploitation in Zigui County, Three Gorges Reservoir Areas of China were presented. The sustainable development mode and its strategy in the Three Gorges Reservoir Areas was also discussed. A sustainable development framework for low mountain regions, middle mountain regions and high mountain regions was developed, and management countermeasures for structural optimization of complex ecosystems were advanced.
文摘The study profiles and explains the significant changes that have taken place in China's spatial development patterns since the inception of its economic reform and opening two decades ago. Principal component analysis is used to delineate spatial patterns. The analyses show that prior to the reform China's spatial development pattern was characterized by the dominance of the three municipalities and the Northeast, as well as by both the coast-interior and the north-south disparities. Northern provinces were generally more industrialized and economically powerful than the southern ones. After two decades of reform, regional development has become multi-centered with South China, the Yangtze Delta and the Beijing-Tianjin area being the three most important regions of the country. The coastal provinces as a whole rose to prominence on China's economic map while the Northeast has diminished its clout. The coast-interior gap not only remains but may have widened. The north-south disparity also still exists but there has been a role reversal with the south now in the lead position. Virtually all inland provinces now find themselves at or near the low end of the development spectrum. We argue that the major reason for the recent shifts in Chinese space economy is the spatially differentiated economic growth resulted from the reform and open door policy and from the new, uneven development strategy adopted by the Chinese government. The paper discusses four specific factors that have reshaped China's spatial development patterns.
基金Supported by Youth Project of National Social Science Fund of China(22CMZ015)。
文摘"Three new developments"is the guiding ideology of Chinese-style high-quality development in the new era.Jujube(Zizyphus jujube Mill.)is a plant of Zizyphus of Rhamnaceae,which originated in China and has been listed as one of the"five fruits"since ancient times.Xinjiang is the most important jujube producing area in China,and its yield has accounted for 50%of the national jujube yield.In the five prefectures and cities of southern Xinjiang,as well as the regimental farms of southern and eastern Xinjiang of Xinjiang Production and Construction Corps,the jujube industry is an advantageous characteristic industry in agriculture.This paper studied Xinjiang jujube industry and its agricultural intellectual property resources,analyzed six major issues to be further implemented,such as the"three new developments"thinking and the strategy of building an intellectual property power,and puts forward eight strategies such as coordinating the two markets and two resources to accelerate the construction of a new development pattern and dual circulation of jujube.
文摘This paper examines China’s flying geese paradigm that serves as a key driver of a new pattern of the country’s economic development.Our results suggest that such a major power’s flying geese paradigm has taken shape in the aftermath of the global financial crisis in 2008.However,this paradigm has provincial heterogeneity in that industrial relocation varies across provinces.For instance,China’s central and western regions have shown differences while serving as destinations for labor-intensive industries and processing trade.This flying geese paradigm evolves in a slow and nonlinear manner,and may be subject to stagnation and even reversal.
文摘On the way to the construction of new countryside, Henan province has been exploring its own new construction development pattern actively. This paper analyzes the four development patterns-Xingyang mode, Zhongmou mode,Xinmi mode and Gongyi mode --from the perspective of ecological civilization development on the basis of sufficient data and extensive research. This also concludes their experience to realize the sustainable development of the new construction of new countryside.
文摘In coping with the global financial crisis, all levels of the Chinese government and foreign trade firms have not only created new practices but have also changed their goal from transforming the growth pattern of foreign trade to transforming the development pattern of joreign trade. China＇s experience shows that economic instruments such as Net Barter Terms of Trade （NBTT） and the smile curve theory have limitations when it comes to interpreting foreign trade. If used improperly, scientific theories often lead to.fallacies. Transjbrming the development pattern of China＇s .foreign trade requires the following changes： national income distribution, foreign trade competition, market exploration, and resource utilization. We advise that competent authorities create a reasonable and operational system of assessment indicators.
文摘Taking rural sports development model in Xvchang as the research object, the article has given an investigation on status of rural sports development in Xvchang with the literature material method, interviewing method, questionnaire survey, and analyzed the influential factors to offer the development pattern, which also provides reference for the rapid development of new rural sports and the relevant departments to formulate corresponding policies.
文摘The urban construction of Shanghai will come into a new area since China has deciared to exploit and open Pudong. Based on the analysis on economic development of China and the world, the developmental strategy for Shanghai should take the following contents into consideration: 1) Shanghai should be built into one of the most important intemational and modern supercity in Asian-Pacifie Region. 2) Shanghai should keep the position of the largest economic center of China and important port city for international trade. 3) Shanghai should be taken as growth pole of the Changjiang River Delta. According to the considderations mentioned above, the spatial distribution patten and the management of environment are discassed.
基金supported by the National Natural Science Foundation of China(Grants No.41931293,42271279,42293271,and 41801175).
文摘China has achieved the poverty reduction goal of the United Nations 2030 Agenda for Sustainable Development 10 years ahead of schedule,contributing significantly to global poverty reduction.Despite extended efforts in poverty elimination,there is a lack of quantitative studies categorizing and comparing poverty-elimination counties(PECs)based on their processes.This study proposes an innovative framework for analyzing PECs’development paths from the perspective of population-land-industry(PLI).We quantify the PLI matching degree of PECs in China during the critical phase of the battle against poverty through a multivariate matching model,classify PECs via K-means clustering according to the consistency in PLI matching degree evolution,and summarize the typical development patterns of PECs.Results indicate that the PLI matching degree of PECs in China increased substantially from 2015 to 2020,particularly in eastern areas,while the western region,including the Qinghai-Xizang Plateau and southwestern Xinjiang,shows untapped potential for improvement.Five types of PECs are identified,with the majority(30.1%)showing sustained moderate PLI matching and a minority(9.6%)experiencing long-term PLI mismatch.Industry is the shortfall of various PECs,and effective strategies to facilitate all types of PECs include the development of emerging businesses and the expansion of secondary and tertiary industries.Additionally,enriching rural labor force and increasing farmland use efficiency are essential for optimal PLI matching and positive interaction,ultimately ensuring poverty elimination and sustainable development.
文摘Beginning with increasing effective demand,thedemand-sidereformadvocates for the strategy to expand domestic demand,rectifies distortions in the demand structure,and further aligns demand and supply by reforming the mechanisms for demand formation and regulation,matching supply and demand structures,and easing restrictions on demand.This will enhance economic growth potential and operational efficiency.The demandside reform contributes to developing a super-large-scale market and optimize market functions to form a unified national market.It also helps address significant structural distortions within domestic circulation and move faster to form a new development pattern of dual circulation.As demand-side reform inevitably deals with the vested interests of stakeholders,it presents challenges on par with supplyside structural reform.Therefore,due attention must be given in terms of priority and weight by increasing operational and property household income,transforming governmentt functions,rectifying any excessive market-orientedreforms in certain public service sectors,among others.
文摘In recent years,the changes in the external environment and domestic development conditions have promoted the transformation of China's economy to one dominated by domestic circulation.In December 2020,the Communist Party of China Central Committee put forward the demand-side reform for the first time in order to prepare China for the new development stage of the 14th Five-Year Plan(2021-2025)and to promote the new strategic deployment of China's high-quality development.Based on the paths and direction of the current 14thFive-YearPlan(2021-2015)tobuild a new development pattern,this paper elaborates on the theoretical connotations of the demand-side reform,points out the bottlenecks such as the unreasonable demand structure in China,the mismatch between the industrial system and the high-level demand,the resulting demand spillovers,the poor demand channels,and puts forward the current approaches to thedemand-sideereform in China.
基金supported by the Public Welfare Research Project for Environmental Protection (No. 201109048)the National High Technology Research and Development Program (863) of China (No. 2012AA06A302)the National Natural Science Foundation of China (No. 21077125)
文摘Considering some advantages of Rana nigromaculata as an experimental species, we propose that this species, like Xenopus laevis, could be used to assay thyroid hormone（TH） signaling disrupting actions. To validate the utilizability of R. nigromaculata, we investigated the responsiveness of R. nigromaculata to a TH receptor（TR） agonist（T3） and antagonist（amiodarone） by analyzing expression, based on characterizing TR cDNA and developmental expression patterns. With high levels of identity with the corresponding genes in X. laevis, both TRα and TRβ in R. nigromaculata exhibited roughly similar developmental expression patterns to those of X. laevis, in spite of some species-specific differences. Both TRα and TRβ expression had greater changes in the liver and intestine than in the tail and brain during metamorphosis. T3 exposure for 2 days induced more dramatic increases of TRβ expression in stage 27 than in stage34 tadpoles but not in stage 42 tadpoles, showing that the responsiveness of R. nigromaculata to TH decreased with development and disappeared at the onset of metamorphic climax.Corresponding to greater changes of TRβ expression in the liver and intestine than in the tail and brain during metamorphosis, the liver and intestine had higher responsiveness to exogenous T3 than the tail and brain. Amiodarone inhibited T3-induced TRβ expression. Our results show that R. nigromaculata can be used as a model species for assaying TH signaling disrupting actions by analyzing TRβ expression, and intestine tissues at stage 27 are ideal test materials due to high responsiveness and easy accessibility.
文摘The overall regional development planning pattern has been considered to be a new and effective pattern as for development of provincial economy.The article analyzed the current conditions of the west of Shandong Province and tried to find the generation mechanisms of current non-balanced economic development of Shandong Province.And then approaches to regional development were put forward according to the theory of regional development pattern as a whole.
文摘Foeused on the lack of proper organization for patterns in the development of pattern based software, a POMSDP model with layered tree structure for organizing patterns during the process of development was put torward. The model and its interrelated eoneepts were strictly defined and introduced by applying the theory of set, symbolie logic and pattern, which ensures the correctness, maturity and expansibility of the model. The expansibility of the model was discussed mainly. The basic realization and the application in the automatic query system were presented. Based on the existing software development methods, the POMSDP model resolves the problem of chaos in the application of patterns, strengthens the controllability of the system, and facilitates the improvement, maintenance, expansion, and especially the reengineering of the software system.
文摘Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncertainty.The fact that the Ukrainian Crisis has dragged on for long and that
文摘Consumption pattern of beta carotene rich foods from 500 households of Coimbatore district was elicited. Through market surveys in four seasons namely: summer, south-west monsoon, north-east monsoon and winter, a year calendar of beta carotene rich foods was developed. The total and beta carotene contents of five commonly consumed beta carotene rich foods both in raw and cooked states were determined. Results indicated that greens were mainly purchased from market and consumed 2-3 times per week. Cooking loss was maximum in boiling and minimum in shallow fat frying. Curry leaves (Murraya koenigii),amaranth tender (Amaranthus gangeticus), agathi (Sesbania grandopra), and ponnanganni (Alternanthera sessilis) were the carotene rich foods available round the year. Cost of most greens was highest in summer and lowest in north-east monsoon. Within a cost of 13-14 ps in summer, 4-10 ps in south-west monsoon and north-west monsoon and 4-12 ps in winter season, the entire day's requirement of beta carotene (2400μg) could be obtained in the form of agathi/amaranth throughout the year: in the form of drumstick leaves and mint in south-west monsoon; as curry leaves and coriander leaves in winter and as agathi,paruppukeerai and amaranth in summer. From this year calendar, according to seasonal availability and cost, low-cost high carotene foods can be selected and used for increasing the beta carotene intake in the intervention programmes and in the community
