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Decision-making Principles and Evaluation Frame of Harmonious Fiscal Policy
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作者 Xiang Hongqiao 《Ecological Economy》 2005年第4期76-79,共4页
Harmonious fiscal policy is the Inner requirement for Constructing Harmonious society and is an important means of realiziug such society. The harmonious fiscal policy should realize the harmony of “two hands”, the ... Harmonious fiscal policy is the Inner requirement for Constructing Harmonious society and is an important means of realiziug such society. The harmonious fiscal policy should realize the harmony of “two hands”, the harmony of values, the unity of short-term and long-term harmony the unity of parts and the whole harmony, the unity of internal and external efficacy harmony. To scientifically evaluate harmony of fiscal policy is the prerequisite to bring harmonious fiscal policy to its full play. 展开更多
关键词 harmonious fiscal policy internal harmony external efficacy harmony decision-making principles evaluation frame
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An Integrated Approach to Condition-Based Maintenance Decision-Making of Planetary Gearboxes: Combining Temporal Convolutional Network Auto Encoders with Wiener Process
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作者 Bo Zhu Enzhi Dong +3 位作者 Zhonghua Cheng Xianbiao Zhan Kexin Jiang Rongcai Wang 《Computers, Materials & Continua》 2026年第1期661-686,共26页
With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance s... With the increasing complexity of industrial automation,planetary gearboxes play a vital role in largescale equipment transmission systems,directly impacting operational efficiency and safety.Traditional maintenance strategies often struggle to accurately predict the degradation process of equipment,leading to excessive maintenance costs or potential failure risks.However,existing prediction methods based on statistical models are difficult to adapt to nonlinear degradation processes.To address these challenges,this study proposes a novel condition-based maintenance framework for planetary gearboxes.A comprehensive full-lifecycle degradation experiment was conducted to collect raw vibration signals,which were then processed using a temporal convolutional network autoencoder with multi-scale perception capability to extract deep temporal degradation features,enabling the collaborative extraction of longperiod meshing frequencies and short-term impact features from the vibration signals.Kernel principal component analysis was employed to fuse and normalize these features,enhancing the characterization of degradation progression.A nonlinear Wiener process was used to model the degradation trajectory,with a threshold decay function introduced to dynamically adjust maintenance strategies,and model parameters optimized through maximum likelihood estimation.Meanwhile,the maintenance strategy was optimized to minimize costs per unit time,determining the optimal maintenance timing and preventive maintenance threshold.The comprehensive indicator of degradation trends extracted by this method reaches 0.756,which is 41.2%higher than that of traditional time-domain features;the dynamic threshold strategy reduces the maintenance cost per unit time to 55.56,which is 8.9%better than that of the static threshold optimization.Experimental results demonstrate significant reductions in maintenance costs while enhancing system reliability and safety.This study realizes the organic integration of deep learning and reliability theory in the maintenance of planetary gearboxes,provides an interpretable solution for the predictive maintenance of complex mechanical systems,and promotes the development of condition-based maintenance strategies for planetary gearboxes. 展开更多
关键词 Temporal convolutional network autoencoder full lifecycle degradation experiment nonlinear Wiener process condition-based maintenance decision-making fault monitoring
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Thermally Drawn Flexible Fiber Sensors:Principles,Materials,Structures,and Applications
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作者 ZhaoLun Zhang Yuchang Xue +7 位作者 Pengyu Zhang Xiao Yang Xishun Wang Chunyang Wang Haisheng Chen Xinghua Zheng Xin Yin Ting Zhang 《Nano-Micro Letters》 2026年第1期95-129,共35页
Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexib... Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexible fiber sensors.Through the preform-tofiber manufacturing technique,a variety of fiber sensors with complex functionalities spanning from the nanoscale to kilometer scale can be automated in a short time.Examples include temperature,acoustic,mechanical,chemical,biological,optoelectronic,and multifunctional sensors,which operate on diverse sensing principles such as resistance,capacitance,piezoelectricity,triboelectricity,photoelectricity,and thermoelectricity.This review outlines the principles of the thermal drawing process and provides a detailed overview of the latest advancements in various thermally drawn fiber sensors.Finally,the future developments of thermally drawn fiber sensors are discussed. 展开更多
关键词 Thermally drawn fiber sensors Sensing principles Temperature sensors Mechanical sensors Multifunctional sensors
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Voices that matter:The impact of patient-reported outcome measures on clinical decision-making 被引量:1
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作者 Naveen Jeyaraman Madhan Jeyaraman +2 位作者 Swaminathan Ramasubramanian Sangeetha Balaji Sathish Muthu 《World Journal of Methodology》 2025年第2期54-61,共8页
The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a pati... The critical role of patient-reported outcome measures(PROMs)in enhancing clinical decision-making and promoting patient-centered care has gained a profound significance in scientific research.PROMs encapsulate a patient's health status directly from their perspective,encompassing various domains such as symptom severity,functional status,and overall quality of life.By integrating PROMs into routine clinical practice and research,healthcare providers can achieve a more nuanced understanding of patient experiences and tailor treatments accordingly.The deployment of PROMs supports dynamic patient-provider interactions,fostering better patient engagement and adherence to tre-atment plans.Moreover,PROMs are pivotal in clinical settings for monitoring disease progression and treatment efficacy,particularly in chronic and mental health conditions.However,challenges in implementing PROMs include data collection and management,integration into existing health systems,and acceptance by patients and providers.Overcoming these barriers necessitates technological advancements,policy development,and continuous education to enhance the acceptability and effectiveness of PROMs.The paper concludes with recommendations for future research and policy-making aimed at optimizing the use and impact of PROMs across healthcare settings. 展开更多
关键词 Patient-reported outcome measures Clinical decision-making Patient-centered care Healthcare technology Data management Policy development
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Rule-Guidance Reinforcement Learning for Lane Change Decision-making:A Risk Assessment Approach 被引量:1
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作者 Lu Xiong Zhuoren Li +2 位作者 Danyang Zhong Puhang Xu Chen Tang 《Chinese Journal of Mechanical Engineering》 2025年第2期344-359,共16页
To solve problems of poor security guarantee and insufficient training efficiency in the conventional reinforcement learning methods for decision-making,this study proposes a hybrid framework to combine deep reinforce... To solve problems of poor security guarantee and insufficient training efficiency in the conventional reinforcement learning methods for decision-making,this study proposes a hybrid framework to combine deep reinforcement learning with rule-based decision-making methods.A risk assessment model for lane-change maneuvers considering uncertain predictions of surrounding vehicles is established as a safety filter to improve learning efficiency while correcting dangerous actions for safety enhancement.On this basis,a Risk-fused DDQN is constructed utilizing the model-based risk assessment and supervision mechanism.The proposed reinforcement learning algorithm sets up a separate experience buffer for dangerous trials and punishes such actions,which is shown to improve the sampling efficiency and training outcomes.Compared with conventional DDQN methods,the proposed algorithm improves the convergence value of cumulated reward by 7.6%and 2.2%in the two constructed scenarios in the simulation study and reduces the number of training episodes by 52.2%and 66.8%respectively.The success rate of lane change is improved by 57.3%while the time headway is increased at least by 16.5%in real vehicle tests,which confirms the higher training efficiency,scenario adaptability,and security of the proposed Risk-fused DDQN. 展开更多
关键词 Autonomous driving Reinforcement learning decision-making Risk assessment Safety filter
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The Credit Risk Assessment Model of Internet Supply Chain Finance: Multi-Criteria Decision-Making Model with the Principle of Variable Weight 被引量:1
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作者 Yueliang Su Baoyu Zhong 《Journal of Computer and Communications》 2017年第1期20-30,共11页
The characteristics of the financing model are firstly analyzed when the e-commerce enterprises participate in the supply chain finance. Internet supply chain finance models are divided into three categories with the ... The characteristics of the financing model are firstly analyzed when the e-commerce enterprises participate in the supply chain finance. Internet supply chain finance models are divided into three categories with the standard of whether the electronic commerce enterprises provide funds for small and medium enterprises instead of banks. And then we further study the financing process and the functions of the e-commerce platform with specific examples. Finally, combined with the characteristics of the supply chain finance model, we set up a small and medium enterprises credit evaluation model based on the principle of variable weight with its dynamic data. At the same time, a multi-time points and multi-indicators decision-making method based on the principle of variable weight is proposed and a specific example is presented. In this paper, the multi-criteria decision-making model with the principle of variable weight has been used two times. At last, a typical case has been analyzed based on this model with a higher accuracy rate of credit risk assessment. 展开更多
关键词 CREDIT Risk Assessment MODEL MULTI-CRITERIA decision-making MODEL Variable principlE
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A Synergistic Multi-Attribute Decision-Making Method for Educational Institutions Evaluation Using Similarity Measures of Possibility Pythagorean Fuzzy Hypersoft Sets
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作者 Khuram Ali Khan Saba Mubeen Ishfaq +1 位作者 Atiqe Ur Rahman Salwa El-Morsy 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期501-530,共30页
Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pP... Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison. 展开更多
关键词 Hypersoft set Pythagorean fuzzy hypersoft set computational complexity multi-attribute decision-making optimization similarity measures uncertainty
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Medical Diagnosis Based on Multi-Attribute Group Decision-Making Using Extension Fuzzy Sets,Aggregation Operators and Basic Uncertainty Information Granule
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作者 Anastasios Dounis Ioannis Palaiothodoros Anna Panagiotou 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期759-811,共53页
Accurate medical diagnosis,which involves identifying diseases based on patient symptoms,is often hindered by uncertainties in data interpretation and retrieval.Advanced fuzzy set theories have emerged as effective to... Accurate medical diagnosis,which involves identifying diseases based on patient symptoms,is often hindered by uncertainties in data interpretation and retrieval.Advanced fuzzy set theories have emerged as effective tools to address these challenges.In this paper,new mathematical approaches for handling uncertainty in medical diagnosis are introduced using q-rung orthopair fuzzy sets(q-ROFS)and interval-valued q-rung orthopair fuzzy sets(IVq-ROFS).Three aggregation operators are proposed in our methodologies:the q-ROF weighted averaging(q-ROFWA),the q-ROF weighted geometric(q-ROFWG),and the q-ROF weighted neutrality averaging(qROFWNA),which enhance decision-making under uncertainty.These operators are paired with ranking methods such as the similarity measure,score function,and inverse score function to improve the accuracy of disease identification.Additionally,the impact of varying q-rung values is explored through a sensitivity analysis,extending the analysis beyond the typical maximum value of 3.The Basic Uncertain Information(BUI)method is employed to simulate expert opinions,and aggregation operators are used to combine these opinions in a group decisionmaking context.Our results provide a comprehensive comparison of methodologies,highlighting their strengths and limitations in diagnosing diseases based on uncertain patient data. 展开更多
关键词 Medical diagnosis multi-attribute group decision-making(MAGDM) q-ROFS IVq-ROFS BUI aggregation operators similarity measures inverse score function
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The Credit Risk Assessment Model of Internet Supply Chain Finance: Multi-Criteria Decision-Making Model with the Principle of Variable Weight 被引量:1
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作者 Yueliang Su Baoyu Zhong 《Journal of Computer and Communications》 2016年第16期1-11,共11页
The characteristics of the financing model are firstly analyzed when the e-commerce enterprises participate in the supply chain finance. Internet supply chain finance models are divided into three categories with the ... The characteristics of the financing model are firstly analyzed when the e-commerce enterprises participate in the supply chain finance. Internet supply chain finance models are divided into three categories with the standard of whether the Electronic commerce enterprises provide funds for small and medium enterprises instead of banks. And then we further study the financing process and the functions of the e-commerce platform with specific examples. Finally, combined with the characteristics of the supply chain finance model, we set up a small and medium enterprises credit evaluation model based on the principle of variable weight with its dynamic data. At the same time, a multi time points and multi indicators decision-making method based on the principle of variable weight is proposed and a specific example is presented. In this paper, the Multi-criteria decision-making model with the principle of variable weight has been used two times. At last, a typical case has been analyzed based on this model with a higher accuracy rate of credit risk assessment. 展开更多
关键词 Credit Risk Assessment Model Multi-Criteria decision-making Model Variable principle
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Healthcare providers’perspectives on factors influencing their critical care decision-making during the COVID-19 pandemic:An international pilot survey
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作者 Sonali Vadi Neha Sanwalka Pramod Thaker 《World Journal of Critical Care Medicine》 2025年第1期100-110,共11页
BACKGROUND Understanding a patient's clinical status and setting priorities for their care are two aspects of the constantly changing process of clinical decision-making.One analytical technique that can be helpfu... BACKGROUND Understanding a patient's clinical status and setting priorities for their care are two aspects of the constantly changing process of clinical decision-making.One analytical technique that can be helpful in uncertain situations is clinical judgment.Clinicians must deal with contradictory information,lack of time to make decisions,and long-term factors when emergencies occur.AIM To examine the ethical issues healthcare professionals faced during the coronavirus disease 2019(COVID-19)pandemic and the factors affecting clinical decision-making.METHODS This pilot study,which means it was a preliminary investigation to gather information and test the feasibility of a larger investigation was conducted over 6 months and we invited responses from clinicians worldwide who managed patients with COVID-19.The survey focused on topics related to their professional roles and personal relationships.We examined five core areas influencing critical care decision-making:Patients'personal factors,family-related factors,informed consent,communication and media,and hospital administrative policies on clinical decision-making.The collected data were analyzed using the χ^(2) test for categorical variables.RESULTS A total of 102 clinicians from 23 specialties and 17 countries responded to the survey.Age was a significant factor in treatment planning(n=88)and ventilator access(n=78).Sex had no bearing on how decisions were made.Most doctors reported maintaining patient confidentiality regarding privacy and informed consent.Approximately 50%of clinicians reported a moderate influence of clinical work,with many citing it as one of the most important factors affecting their health and relationships.Clinicians from developing countries had a significantly higher score for considering a patient's financial status when creating a treatment plan than their counterparts from developed countries.Regarding personal experiences,some respondents noted that treatment plans and preferences changed from wave to wave,and that there was a rapid turnover of studies and evidence.Hospital and government policies also played a role in critical decision-making.Rather than assessing the appropriateness of treatment,some doctors observed that hospital policies regarding medications were driven by patient demand.CONCLUSION Factors other than medical considerations frequently affect management choices.The disparity in treatment choices,became more apparent during the pandemic.We highlight the difficulties and contradictions between moral standards and the realities physicians encountered during this medical emergency.False information,large patient populations,and limited resources caused problems for clinicians.These factors impacted decision-making,which,in turn,affected patient care and healthcare staff well-being. 展开更多
关键词 SURVEY Clinical decision-making COVID-19 pandemic
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First-principles study on the structure-property relationship of AlX and InX(X=N,P,As,Sb)
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作者 HE Zhihao DING Jiafu +1 位作者 WANG Yunjie SU Xin 《无机化学学报》 北大核心 2025年第5期1007-1019,共13页
This paper delves into the theoretical mechanisms of the electronic structure and optical properties of aluminum-based semiconductors(AlX,X=N,P,As,Sb)and indium-based semiconductors(InX,X=N,P,As,Sb)as potential materi... This paper delves into the theoretical mechanisms of the electronic structure and optical properties of aluminum-based semiconductors(AlX,X=N,P,As,Sb)and indium-based semiconductors(InX,X=N,P,As,Sb)as potential materials for optical devices.Band structure calculations reveal that,except for InSb,all other compounds are direct bandgap semiconductors,with AlN exhibiting a bandgap of 3.245 eV.The valence band maximum of these eight compounds primarily stems from the p-orbitals of Al/In and X.In contrast,the conduction band minimum is influenced by all orbitals,with a predominant contribution from the p-orbitals.The static dielectric constant increased with the expansion of the unit cell volume.Compared to AlX and InX with larger X atoms,AlN and InN showed broader absorption spectra in the near-ultraviolet region and higher photoelectric conductance.Regarding mechanical properties,AlN and InN displayed greater shear and bulk modulus than the other compounds.Moreover,among these eight crystal types,a higher modulus was associated with a lower light loss function value,indicating that AlN and InN have superior transmission efficiency and a wider spectral range in optoelectronic material applications. 展开更多
关键词 aluminium‑based semiconductor indium‑based semiconductor first principle electronic structure optical property
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The relationship between proxy decision-making content and cues by families of patients with malignant brain tumor: A descriptive qualitative study
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作者 Runa Tokunaga Fumiyo Ishikawa 《International Journal of Nursing Sciences》 2025年第2期169-175,共7页
Objectives This study aimed to clarify the relationship between the content of proxy decision-making made by families of patients with malignant brain tumors regarding treatment policies and daily care and the cues le... Objectives This study aimed to clarify the relationship between the content of proxy decision-making made by families of patients with malignant brain tumors regarding treatment policies and daily care and the cues leading to those decisions.Methods Semi-structured personal interviews were used to collect data.Seven family members of patients with malignant brain tumors were selected to participate in the study by purposive sampling method from June to August 2022 in the Patient Family Association of Japan.Responses were content analyzed to explore the relationship between the content of decisions regarding“treatment policies”and“daily care”and the cues influencing those decisions.Semi-structured interviews were analyzed by using thematic analysis.Results The contents of proxy decisions regarding“treatment policies”included implementation,interruption,and termination of initial treatments,free medical treatments,use of respirators,and end-of-life sedation and included six cues:treatment policies suggested by the primary physician,information and knowledge about the disease and treatment obtained by the family from limited resources,perceived life threat from symptom worsening,words and reactions from the patient regarding treatment,patient’s personality and way of life inferred from their treatment preferences,family’s thoughts and values hoping for better treatment for the patient.Decisions for“daily care”included meal content and methods,excretion,mobility,maintaining cleanliness,rehabilitation,continuation or resignation from work,treatment settings(outpatient or inpatient),and ways to spend time outside and included seven cues:words and thoughts from the patient about their way of life,patient’s reactions and life history inferred from their preferred way of living,things the patient can do to maintain daily life and roles,awareness of the increasing inability to do things in daily life,family’s underlying thoughts and values about how to spend the remaining time,approval from family members regarding the care setting,advice from medical professionals on living at home.Conclusions For“treatment policies,”guidelines from medical professionals were a key cue,while for“daily care,”the small signs from the patients in their daily lives served as cues for proxy decision-making.This may be due to the lack of information available to families and the limited time available for discussion with the patient.Families of patients with malignant brain tumors repeatedly use multiple cues to make proxy decision-making under high uncertainty.Therefore,nurses supporting proxy decision-making should assess the family’s situation and provide cues that facilitate informed and confident decisions. 展开更多
关键词 Brain neoplasms FAMILY Nurses CUES Proxy decision-making
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First-principles Investigation of Heavy Metal Adsorption on C-lignin
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作者 WANG Juan JIA Leiyu +3 位作者 XU Yao ZHANG Zhenzhen DUAN Ziyu ALBINA Jan-Michael 《Journal of Wuhan University of Technology(Materials Science)》 2025年第6期1790-1794,共5页
We investigated the adsorption mechanisms including physical and chemical adsorption for heavy metals(Cd,Pb,Zn,Co,Cu)on C-lignin using density functional theory(DFT)simulations.Physical adsorption,involving metal atom... We investigated the adsorption mechanisms including physical and chemical adsorption for heavy metals(Cd,Pb,Zn,Co,Cu)on C-lignin using density functional theory(DFT)simulations.Physical adsorption,involving metal atoms near carbon atoms,is found to be endothermic;meanwhile,chemical adsorption,where hydroxyl groups replace metal ions,is exothermic and spontaneous.Pb exhibits the highest physical adsorption potential,while Cu and Co demonstrate the strongest chemical adsorption due to their highly negative adsorption energies.These findings provide valuable insights into the design of eco-friendly nano lignocellulosic composite films for effective heavy metal removal from contaminated water sources.Key words:C-lignin;adsorption;We investigated the adsorption mechanisms including physical and chemical adsorption for heavy metals(Cd,Pb,Zn,Co,Cu)on C-lignin using density functional theory(DFT)simulations.Physical adsorption,involving metal atoms near carbon atoms,is found to be endothermic;meanwhile,chemical adsorption,where hydroxyl groups replace metal ions,is exothermic and spontaneous.Pb exhibits the highest physical adsorption potential,while Cu and Co demonstrate the strongest chemical adsorption due to their highly negative adsorption energies.These findings provide valuable insights into the design of eco-friendly nano lignocellulosic composite films for effective heavy metal removal from contaminated water sources. 展开更多
关键词 C-lignin ADSORPTION heavy metal ions first principles calculations metal ions first principles calculations
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Sexually differentiated decision-making involves faster recruitment in the early stages for the Tibetan antelopes Pantholops hodgsonii
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作者 Qin Zhu Jian Guan +6 位作者 Tianya Lei Kun Xuan Sile Guo Yumeng Zhao Changjian Fu Le Yang Zhongqiu Li 《Current Zoology》 2025年第1期124-135,共12页
Group living is widespread across diverse taxa,and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding the dynamics of group stability.While studie... Group living is widespread across diverse taxa,and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding the dynamics of group stability.While studies on collective behavior in small animals such as fish and insects are well-established,similar research on large wild animals remains challenging due to the limited availability of sufficient and systematic field data.Here,we aimed to explore the collective decision-making pattern and its sexual difference for the dimorphic Tibetan antelopes Pantholops hodgsonii(chiru)in Xizang Autonomous Region,China,by analyzing individual leadership distribution,as well as the joining process,considering factors such as calving stages and joining ranks.The distinct correlations of decision participants’ratio with group size and decision duration underscore the trade-off between accuracy and speed in decision-making.Male antelopes display a more democratic decision-making pattern,while females exhibit more prompt responses after calving at an early stage.This study uncovers a partially shared decision-making strategy among Tibetan antelopes,suggesting flexible self-organization in group decision processes aligned with animal life cycle progression. 展开更多
关键词 calving stage decision-making LEADERSHIP sexual differences Tibetan antelopes
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UNCERTAINTY PRINCIPLES AND SIGNAL RECOVERY RELATED TO THE CANONICAL FOURIER-BESSEL TRANSFORM
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作者 Jihed SAHBANI Lazhar DHAOUADI 《Acta Mathematica Scientia》 2025年第5期2190-2207,共18页
The aim of this paper is to prove another variation on the Heisenberg uncertainty principle,we generalize the quantitative uncertainty relations in n different(time-frequency)domains and we will give an algorithm for ... The aim of this paper is to prove another variation on the Heisenberg uncertainty principle,we generalize the quantitative uncertainty relations in n different(time-frequency)domains and we will give an algorithm for the signal recovery related to the canonical Fourier-Bessel transform. 展开更多
关键词 Fourier Bessel transform linear canonical transform quantitative uncertainty principles Heisenberg uncertainty principle signal recovery
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Shared decision-making improves adherence to mesalamine in ulcerative colitis:A prospective,multicenter,non-interventional cohort study in Germany
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作者 Wolfgang Kruis Petra Jessen +3 位作者 Julia Morgenstern Birgitta Reimers Nike Müller-Grage Bernd Bokemeyer 《World Journal of Gastroenterology》 2025年第22期49-59,共11页
BACKGROUND Mesalamine is the recommended first-line treatment for inducing and maintaining remission in mild-to-moderate ulcerative colitis(UC).However,adherence in real-world settings is frequently suboptimal.Encoura... BACKGROUND Mesalamine is the recommended first-line treatment for inducing and maintaining remission in mild-to-moderate ulcerative colitis(UC).However,adherence in real-world settings is frequently suboptimal.Encouraging collaborative patient-provider relationships may foster better adherence and patient outcomes.AIM To quantify the association between patient participation in treatment decisionmaking and adherence to oral mesalamine in UC.METHODS We conducted a 12-month,prospective,non-interventional cohort study at 113 gastroenterology practices in Germany.Eligible patients were aged≥18 years,had a confirmed UC diagnosis,had no prior mesalamine treatment,and provided informed consent.At the first visit,we collected data on demographics,clinical characteristics,patient preference for mesalamine formulation(tablets or granules),and disease knowledge.Self-reported adherence and disease activity were assessed at all visits.Correlation analyses and logistic regression were used to examine associations between adherence and various factors.RESULTS Of the 605 consecutively screened patients,520 were included in the study.The median age was 41 years(range:18-91),with a male-to-female ratio of 1.1:1.0.Approximately 75%of patients reported good adherence at each study visit.In correlation analyses,patient participation in treatment decision-making was significantly associated with better adherence across all visits(P=0.04).In the regression analysis at 12 months,this association was evident among patients who both preferred and received prolonged-release mesalamine granules(odds ratio=2.73,P=0.001).Patients reporting good adherence also experienced significant improvements in disease activity over 12 months(P<0.001).CONCLUSION Facilitating patient participation in treatment decisions and accommodating medication preferences may improve adherence to mesalamine.This may require additional effort but has the potential to improve long-term management of UC. 展开更多
关键词 Ulcerative colitis ADHERENCE Shared decision-making MESALAMINE Drug formulation GRANULES
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AGU Posts Principles to Guide-and Foster-Geoengineering Research
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作者 Sean Cummings 《Engineering》 2025年第9期10-13,共4页
On 17 October 2024,the American Geophysical Union(AGU)in Washington,DC,USA,released the Ethical Framework Principles for Climate Intervention Research[1],a set of guidelines designed to help scientists,funders,policym... On 17 October 2024,the American Geophysical Union(AGU)in Washington,DC,USA,released the Ethical Framework Principles for Climate Intervention Research[1],a set of guidelines designed to help scientists,funders,policymakers,and private entities research and govern geoengineering technologies as ethically as possible.Commissioned in 2022 by the AGU Board of Directors and produced with internal funding only,the document advocates that geoengineering research projects fully consider all possible risks and benefits-environmental,sociocultural,and geopolitical-and include input from any groups such projects might impact. 展开更多
关键词 ethical framework environmental risks GEOENGINEERING geopolitical considerations research principles climate intervention sociocultural impacts ethical framework principles
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Data-Driven Component-Level Decision-Making for Online Remanufacturing of Gas-Insulated Switchgear
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作者 Hansam Cho Seokho Moon +2 位作者 Sunhyeok Hwang Seoung Bum Kim Younghoon Kim 《Computer Modeling in Engineering & Sciences》 2025年第11期1941-1967,共27页
Accurately determining when and what to remanufacture is essential for maximizing the lifecycle value of industrial equipment.However,existing approaches face three significant limitations:(1)reliance on predefined ma... Accurately determining when and what to remanufacture is essential for maximizing the lifecycle value of industrial equipment.However,existing approaches face three significant limitations:(1)reliance on predefined mathematical models that often fail to capture equipment-specific degradation,(2)offline optimization methods that assume access to future data,and(3)the absence of component-level guidance.To address these challenges,we propose a data-driven framework for component-level decision-making.The framework leverages streaming sensor data to predict the remaining useful life(RUL)without relying on mathematical models,employs an online optimization algorithm suitable for practical settings,and,through remanufacturing simulations,provides guidance on which components should be replaced.In a case study on gas-insulated switchgear,the proposed framework achieved RUL prediction performance comparable to an oracle model in an online setting without relying on predefined mathematical models.Furthermore,by employing online optimization,it determined a remanufacturing timing close to the global optimum using only past and current data.In addition,unlike previous studies,the framework enables component-level decision-making,allowing for more detailed and actionable remanufacturing guidance in practical applications. 展开更多
关键词 REMANUFACTURING online decision-making gas-insulated switchgear online learning
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Influence of negative information dissemination and vaccination behavioral decision-making on epidemic spreading in a three-layer network
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作者 Liang'an Huo Leyao Yin 《Chinese Physics B》 2025年第6期667-681,共15页
Information plays a crucial role in guiding behavioral decisions during public health emergencies. Individuals communicate to acquire relevant knowledge about an epidemic, which influences their decisions to adopt pro... Information plays a crucial role in guiding behavioral decisions during public health emergencies. Individuals communicate to acquire relevant knowledge about an epidemic, which influences their decisions to adopt protective measures.However, whether to disseminate specific information is also a behavioral decision. In light of this understanding, we develop a coupled information–vaccination–epidemic model to depict these co-evolutionary dynamics in a three-layer network. Negative information dissemination and vaccination are treated as separate decision-making processes. We then examine the combined effects of herd and risk motives on information dissemination and vaccination decisions through the lens of game theory. The microscopic Markov chain approach(MMCA) is used to describe the dynamic process and to derive the epidemic threshold. Simulation results indicate that increasing the cost of negative information dissemination and providing timely clarification can effectively control the epidemic. Furthermore, a phenomenon of diminishing marginal utility is observed as the cost of dissemination increases, suggesting that authorities do not need to overinvest in suppressing negative information. Conversely, reducing the cost of vaccination and increasing vaccine efficacy emerge as more effective strategies for outbreak control. In addition, we find that the scale of the epidemic is greater when the herd motive dominates behavioral decision-making. In conclusion, this study provides a new perspective for understanding the complexity of epidemic spreading by starting with the construction of different behavioral decisions. 展开更多
关键词 negative information VACCINATION epidemic spreading behavioral decision-making three-layer network
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