Objective:This study aims to explore the optimal selection of blending coefficients for non-linear blending(NLB)technology in dual-source dual-energy cra-nial CT angiography(CTA)to enhance image quality and contrast.M...Objective:This study aims to explore the optimal selection of blending coefficients for non-linear blending(NLB)technology in dual-source dual-energy cra-nial CT angiography(CTA)to enhance image quality and contrast.Methods:A total of 48 dual-energy head CT images with a subjective score of less than 3 points in the initial linear fusion image quality were selected for NLB processing.The fixed CTA energy was 70 and 140 kV,and the fusion center λ(0,80,150,250 HU),fusion width ω(0,100,200,300 HU)and total contrast agent(20,22,24,25 mL)were analyzed by comparing the cerebrovascular area of interest of the experimental subjects for image quality scor-ing,and the response surface method was used to determine the optimization parameters of the non-linear fusion technology of dual-energy cranial CTA.Results:According to the mean values of each factor in the orthogonal test,it was found that λ had the highest influence level in K2,ω had the highest influence level in K1,and the total amount of contrast agent K3 had the highest influence level.Range analysis revealed the order of influence as λ>contrast agent volume>ω.Through response surface analysis,the optimal parameters were identified as a blending center λ=125 HU,blending width ω=150 HU,and contrast agent volume=22.50 mL.The average subjective score of LB images was(2.62±0.49),and the subjective image quality scores were higher than those of LB images after NLB processing,with subjective quality scores of(3.79±0.65),with t=21.462 and P=0.000.Conclusion:For dual-energy cranial CTA,the optimal coefficient design for NLB technology can be achieved by selecting λ=125 HU,ω=150 HU,and a contrast agent volume of 22.50 mL,thereby improving contrast-to-noise ratio(CNR)and overall image quality.展开更多
目的探讨前循环急性大血管闭塞性脑卒中(acute large vessel occlusive stroke,ALVOS)机械取栓术后颅脑CT可逆性缺血性水肿的影响因素。方法选取2022年6月至2024年7月于嘉兴市第一医院接受机械取栓治疗的前循环ALVOS患者142例为研究对象...目的探讨前循环急性大血管闭塞性脑卒中(acute large vessel occlusive stroke,ALVOS)机械取栓术后颅脑CT可逆性缺血性水肿的影响因素。方法选取2022年6月至2024年7月于嘉兴市第一医院接受机械取栓治疗的前循环ALVOS患者142例为研究对象,根据机械取栓术后复查颅脑CT结果将其分为不可逆性缺血性水肿组(120例)和可逆性缺血性水肿组(22例)。收集患者的基线临床资料,采用多因素Logistic回归分析前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿的影响因素;构建受试者操作特征曲线(receiver operating characteristic curve,ROC曲线)评估其对可逆性缺血性水肿的预测价值。结果多因素Logistic回归分析结果显示,年龄(OR=1.057,95%CI:1.018~1.102,P=0.005)和侧支循环分级(OR=0.395,95%CI:0.186~0.769,P=0.010)均是前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿的影响因素。ROC曲线结果显示,年龄、侧支循环分级及两者联合均对前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿有一定的预测价值,年龄、侧支循环分级的曲线下面积(area under the curve,AUC)分别为0.664、0.715,两者联合的AUC为0.785,最佳截断值为0.861,敏感度为68.3%,特异性为81.8%。结论少数前循环ALVOS患者行机械取栓术后颅脑CT缺血区域低密度影是可逆的,机械取栓患者较年轻、良好的侧支循环代偿与术后颅脑CT可逆性缺血性水肿有关。展开更多
文摘Objective:This study aims to explore the optimal selection of blending coefficients for non-linear blending(NLB)technology in dual-source dual-energy cra-nial CT angiography(CTA)to enhance image quality and contrast.Methods:A total of 48 dual-energy head CT images with a subjective score of less than 3 points in the initial linear fusion image quality were selected for NLB processing.The fixed CTA energy was 70 and 140 kV,and the fusion center λ(0,80,150,250 HU),fusion width ω(0,100,200,300 HU)and total contrast agent(20,22,24,25 mL)were analyzed by comparing the cerebrovascular area of interest of the experimental subjects for image quality scor-ing,and the response surface method was used to determine the optimization parameters of the non-linear fusion technology of dual-energy cranial CTA.Results:According to the mean values of each factor in the orthogonal test,it was found that λ had the highest influence level in K2,ω had the highest influence level in K1,and the total amount of contrast agent K3 had the highest influence level.Range analysis revealed the order of influence as λ>contrast agent volume>ω.Through response surface analysis,the optimal parameters were identified as a blending center λ=125 HU,blending width ω=150 HU,and contrast agent volume=22.50 mL.The average subjective score of LB images was(2.62±0.49),and the subjective image quality scores were higher than those of LB images after NLB processing,with subjective quality scores of(3.79±0.65),with t=21.462 and P=0.000.Conclusion:For dual-energy cranial CTA,the optimal coefficient design for NLB technology can be achieved by selecting λ=125 HU,ω=150 HU,and a contrast agent volume of 22.50 mL,thereby improving contrast-to-noise ratio(CNR)and overall image quality.
文摘目的探讨前循环急性大血管闭塞性脑卒中(acute large vessel occlusive stroke,ALVOS)机械取栓术后颅脑CT可逆性缺血性水肿的影响因素。方法选取2022年6月至2024年7月于嘉兴市第一医院接受机械取栓治疗的前循环ALVOS患者142例为研究对象,根据机械取栓术后复查颅脑CT结果将其分为不可逆性缺血性水肿组(120例)和可逆性缺血性水肿组(22例)。收集患者的基线临床资料,采用多因素Logistic回归分析前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿的影响因素;构建受试者操作特征曲线(receiver operating characteristic curve,ROC曲线)评估其对可逆性缺血性水肿的预测价值。结果多因素Logistic回归分析结果显示,年龄(OR=1.057,95%CI:1.018~1.102,P=0.005)和侧支循环分级(OR=0.395,95%CI:0.186~0.769,P=0.010)均是前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿的影响因素。ROC曲线结果显示,年龄、侧支循环分级及两者联合均对前循环ALVOS患者机械取栓术后颅脑CT可逆性缺血性水肿有一定的预测价值,年龄、侧支循环分级的曲线下面积(area under the curve,AUC)分别为0.664、0.715,两者联合的AUC为0.785,最佳截断值为0.861,敏感度为68.3%,特异性为81.8%。结论少数前循环ALVOS患者行机械取栓术后颅脑CT缺血区域低密度影是可逆的,机械取栓患者较年轻、良好的侧支循环代偿与术后颅脑CT可逆性缺血性水肿有关。
