To researching the damage characteristics of typical logical chip modules in spacecraft due to plasma generated by hypervelocity impacts,we have established a triple Langmuir probe diagnostic system and a logical chip...To researching the damage characteristics of typical logical chip modules in spacecraft due to plasma generated by hypervelocity impacts,we have established a triple Langmuir probe diagnostic system and a logical chips measurement system,which were used to diagnose plasma characteristic parameters and the logical chip module＇s logical state changes due to the plasma created by a 7075 aluminum projectile hypervelocity impact on the 2A12 aluminum target.Three sets of experiments were performed with the collision speeds of 2.85 km/s,3.1 km/s and2.20 km/s,at the same incident angles of 30 degrees and logical chip module＇s positions by using a two-stage light gas gun loading system,a plasma characteristic parameters diagnostic system and a logical chip module＇s logical state measurement system,respectively.Electron temperature and density were measured at given position and azimuth,and damage estimation was performed for the logical chip module by using the data acquisition system.Experimental results showed that temporary damage could be induced on logical chip modules in spacecraft by plasma generated by hypervelocity impacts under the given experimental conditions and the sensors＇ position and azimuth.展开更多
High-temperature,high-power converters have gained importance in industrial applications given their ability to operate in adverse environments,such as in petroleum exploration,multi-electric aircrafts,and electric ve...High-temperature,high-power converters have gained importance in industrial applications given their ability to operate in adverse environments,such as in petroleum exploration,multi-electric aircrafts,and electric vehicles.SiC metaloxide-semiconductor field-effect transistor(MOSFET),a new,wide bandgap,high-temperature device,is the key component of these converters.In this study,the static and dynamic characteristics of the SiC MOSFET,half-bridge module,are investigated at the junction temperature of 180℃.A simplified experimental method is then proposed pertaining to the power operation of the SiC module at 180℃.This method is based on the use of a thermal resistance test platform and is proven convenient for the study of heat dissipation characteristics.The high-temperature characteristics of the module are verified based on the conducted experiments.Accordingly,a 100 kW high-temperature converter is built,and the test results show that the SiC converter can operate at a junction temperature of 180℃in a stable manner in compliance with the requirements of high-temperature,high-power applications.展开更多
Cholesteric liquid crystals（CLCs） have recently sparked an enormous amount of interest in the development of soft matter materials due to their unique ability to self-organize into a helical supra-molecular architec...Cholesteric liquid crystals（CLCs） have recently sparked an enormous amount of interest in the development of soft matter materials due to their unique ability to self-organize into a helical supra-molecular architecture and their excellent selective reflection of light based on the Bragg relationship.Nowadays,by the virtue of building the self-organized nanostructures with pitch gradient or non-uniform pitch distribution,extensive work has already been performed to obtain CLC films with a broad reflection band.Based on authors＇ many years＇ research experience,this critical review systematically summarizes the physical and optical background of the CLCs with broadband reflection characteristics,methods to obtain broadband reflection of CLCs,as well as the application in the field of intelligent optical modulation materials.Combined with the research status and the advantages in the field,the important basic and applied scientific problems in the research direction are also introduced.展开更多
This paper conducts a research on modulation characteristics of blue light-emitting diodes (LEDs) used in a visible-light communication (VLC) system. Through analysis of the modulation characteristics of LEDs with dif...This paper conducts a research on modulation characteristics of blue light-emitting diodes (LEDs) used in a visible-light communication (VLC) system. Through analysis of the modulation characteristics of LEDs with different emitting sizes, we find that there is a similar linear relationship between LED’s 3dB bandwidth and the operation current density. This experiment also shows that high series resistance is one major issue that limits our LED's modulation speed. To further improve the LED bandwidth, the resistance can be reduced by optimizing device layout as well as reducing material bulk resistance. Clearly, this study provides an approach to increase the modulation bandwidth of GaN-based LEDs for VLC systems.展开更多
It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enha...It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enhanced the secretion of MSC-derived exosomes with stronger anti-inflammatory protein,cytokine profiles,and functional RNA via altering COX2/PGE2 pathway.Recently,accumulating evidence has also revealed that biophysical cues(especially biomechanical cues)in cell microenvironment have significant effects not only on cells but also on their exosomes.It has been reported that applying bi-axial strain to MSCs induces formation of a stiffer cytoskeleton through mTORC2 signaling,which biases against adipogenic differentiation and toward osteoblastogenesis.At the same time,For example,dimensionality,composition and stiffness of the extracellular matrix(ECM)has been proved to affect the size and composition of exosomes secreted by cancer cells.However,the effects of biomechanical cues in the three-dimensional(3D)microenvironment on stem cell-derived exosomes remains to be unveiled.Therefore,it is important to understand the roles of 3D cell mechanical microenvironment in regulating the characteristics of stem cell-derived exosomes and develop more efficient approaches to enhance their functions.This study aimed to explore the changes in characteristics of exosomes secreted by MSCs in periodontium in response to the matrix strain in 3D.Periodontal ligament stem cells(PDLSCs)were cultured in a 3D strain microenvironment engineered with microscale magnetically stretched collagen hydrogels.The morphology,particle distribution,marker protein expression of PDLSC-derived exosomes were analyzed.Then the pro-osteogenic property of exosomes was evaluated by assessing cell viability,proliferation,migration and osteogenic differentiation of target cells,for instance human bone marrow mesenchymal stem cells(hBMSCs).Detailed characterizations revealed that PDLSC-derived exosomes in the 3D strain mi-croenvironment were with similar morphology,particle distribution and surface markers.Notably,Exosomes secreted by PDLSCs in strain microenvironment were more endocytosed by hBMSCs and were more potent in improving proliferation and migration of hBMSCs,comparing with PDLSCs in non-strain environment.Alizarin red staining and molecular biology experiments confirmed that treatment of exosomes secreted by PDLSCs under mechanical stimulation led to a significant increase in osteogenic differentiation of hBMSCs in vitro.Meanwhile,in vivo study also indicated that PDLSC-derived exosomes obtained from the 3D strain microenvironment could obviously promote new bone formation.Our findings revealed that mechanical cues profoundly affected the characteristics of PDLSC-derived exosomes,especially for their bio-activity,providing a foundation for using the 3D mechanical microenvironment to enhance the osteo-inductive functions of stem cell-derived exosomes in cell-free therapy for bone regeneration.展开更多
Based on the scattering characteristic,the comparison of RCS(radar cross-section)at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the entity....Based on the scattering characteristic,the comparison of RCS(radar cross-section)at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the entity.A simulation method of aerial&space targets echo characteristics(A&STEC)is proposed that is universal to aerial and space targets.We utilize a fixed-wing UAV(unmanned aerial vehicle)and typical missiles in simulation.The echo signal modulation characteristic parameters are calculated theoretically by the atmospheric attenuation model,the finite element method and a MUMPS solver.The verification simulations show that this method can analyze the influence of the target shape,incident direction,detection position and detection frequency on echo waveform,intensity and energy distribution.The results show that the profile of echo waveform can invert the general shape of the target.The relationship between time and intensity can determine whether the target is moving towards or away from the detector in addition.These conclusions can provide a reference for the ballistic missile target tracking and the defense against UVA intrusion in theory.展开更多
The electrical modulation valve can provide proportional output valve element displacement,flow,or pressure according to a continuously changing input electrical signal.It is the core component of electro-hydraulic pr...The electrical modulation valve can provide proportional output valve element displacement,flow,or pressure according to a continuously changing input electrical signal.It is the core component of electro-hydraulic proportional control technology.To remove the influence of pressure difference changes on the output flow,the traditional scheme is to use a pressure compensation valve,which increases the difficulty of both manufacturing and maintaining the valve.To solve this problem,a method of digital and mechanical redundancy control flow is proposed.Pressure sensors are installed at the inlet and outlet of the valve,and the controller adjusts the displacement of the valve element according to the pressure difference between the valve ports to realize high-precision control of the flow.A pressure compensation valve is installed in front of the valve,and a three-way solenoid valve is used to control the working of the compensation valve.In the case of sensor failure,the valve is switched to the mechanical compensation differential pressure mode,to control the flow and to achieve redundancy control.The system security is thereby improved.The feasibility of this scheme is verified through simulation and tests.The results show that,both for digital compensation and mechanical compensation,the output flow can be kept constant when the pressure difference changes,and the system has good static and dynamic characteristics.The principle can be applied to the displacement-flow feedback type electrical modulation valve,and can realize accurate control of the flow of the pilot valve and,finally,accurate control of the flow in the main valve.展开更多
Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-sig...Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-signal modulation characteristics of the simultaneous ground-state （GS） and the excited-state （ES） lasing in InAs/OaAs quantum dot laser diodes. The large-signal modulation capability of total light intensity in the transition regime from OS lasing to two-state lasing is unchanged as the bias-current increases. However, GS and ES large-signal eye diagrams show obvious variations during the transition. Relaxation oscillations and large-signal eye diagrams for OS, ES, and total light intensities are numerically simulated and analyzed in detail by using a rate-equation model. The -ndings show that a complementary relationship between the light intensities for OS and ES lasing exists in both the transition regime and the two-state lasing regime, leading to a much smaller overshooting power and a shorter settling time for the total light intensity. Therefore, the eye diagrams of GS or ES lasing are diffuse whereas those of total light intensity are constant as the bias-current increases in the transition regime.展开更多
To reduce thrust ripple and cost and improve the average thrust of permanent magnet linear motors,a modular dual-field modulation permanent magnet linear motor was studied,and the parameters were optimized.First,sensi...To reduce thrust ripple and cost and improve the average thrust of permanent magnet linear motors,a modular dual-field modulation permanent magnet linear motor was studied,and the parameters were optimized.First,sensitive parameters were selected using the Taguchi method,and then the optimal variables were sampled using the optimal Latin hypercube experimental design method and an ensemble of surrogates model of optimization objectives,and its accuracy was verified.Next,a multi-objective particle swarm optimization algorithm was used to optimize the purpose of“maximum average thrust and minimum thrust ripple”,and the Pareto front of average thrust and thrust ripple was obtained.Finite element analysis showed that the optimized modular dual flux-modulation permanent magnet linear motor(MDFMPMLM)had a 29.5%reduction in thrust ripple and a 5%increase in average thrust compared to the original motor.This study provided an effective method for improving the performance of permanent magnet linear motors.展开更多
Natural properties of high speed on-off valves can be described through their on-off behavior and spool movement (static and oscillating) characteristics. High speed on-off valves can be combined with actuators in sys...Natural properties of high speed on-off valves can be described through their on-off behavior and spool movement (static and oscillating) characteristics. High speed on-off valves can be combined with actuators in systems into four typical types of composite valves whose static characteristics are related not only to the structures of the single valves and the composite ones, but also to the PWM control modes. It is proved that the composite valves have similar features as those of servo valves. The nonlinear specific properties of single valves composited can be completely compensated by the suitable PWM control modes.展开更多
A numerical model and transmission characteristic analysis of DPSK （differential phase shift keying） pressure signals in mud channels is introduced. With the control logic analysis of the rotary valve mud telemetry,...A numerical model and transmission characteristic analysis of DPSK （differential phase shift keying） pressure signals in mud channels is introduced. With the control logic analysis of the rotary valve mud telemetry, a logical control signal is built from a Gate function sequence according to the binary symbols of transmitted data and a phase-shift function is obtained by integrating the logical control signal. A mathematical model of the DPSK pressure signal is built based on principles of communications by modulating carrier phase with the phase-shift function and a numerical simulation of the pressure wave is implemented with the mathematical model by MATLAB programming. Considering drillpipe pressure and drilling fluid temperature profile along drillpipes, the drillpipe of a vertical well is divided into a number of sections. With water-based drilling fluids, the impacts of travel distance, carrier frequency, drillpipe size, and drilling fluids on the signal transmission were studied by signal transmission characteristic analysis for all the sections. Numerical calculation results indicate that the influences of the viscosity of drilling fluids and volume fraction of gas in drilling fluids on the DPSK signal transmission are more notable than the others and the signal will distort in waveform with differential attenuations of the signal frequent component.展开更多
Cold atmospheric plasma(CAP)jet has wide applications in various fields including advanced materials synthesis and modifications,biomedicine,environmental protection and energy saving,etc.Appropriate control on the vo...Cold atmospheric plasma(CAP)jet has wide applications in various fields including advanced materials synthesis and modifications,biomedicine,environmental protection and energy saving,etc.Appropriate control on the volume,temperature and chemically reactive species concentratio ns of the CAP jet is of great importance in actual applications.In this paper,an radio-frequency atmospheric-pressure glow discharge(RF-APGD)plasma generator with a hybrid cross-linear-field electrode configuration is proposed.The experimental results show that,with the aid of the copper mesh located at the downstream of the traditional co-axial-type plasma generator with a cross-field electrode configuration,a linear field between the inner powered electrode of the traditional plasma generator and the copper mesh can be established.This linerfield can,to some extent,enhance the discharges at the upstream of the copper mesh,resulting in small increments(all less than 12.5%)of the species emission intensities,electron excitation temperatures and gas temperatures by keeping other parameters being unchanged.And due to the intrinsic transparent and conducting features of the grounded copper mesh to the gas flowing,electric current and heat flux of the plasma plumes,a plasma region with higher concentrations of chemically reactive species and larger plasma plume diameters is obtained at the downstream of the grounded copper mesh on the same level of the gas temperature and electron excitation temperature compared to those of the plasma free jet.In addition,the charged particle number densities at the same downstream axial location of the grounded copper mesh decrease significantly compared to those of the plasma free jet.This means that the copper mesh is also,to some extent,helpful for separating the chemically reactive neutral species from the charged particles in side a plasma environment.The preceding results indicate that the cross-linear-field electrode configuration of the plasma generator is an effective approach for tuning the characteristics of the RF-APGD plasma jet in order to obtain an appropriate combination of the plasma jet properties with higher chemically reactive species concentrations,especially relative higher number densities of neutral species,larger plasma volumes and lower gas temperatures.展开更多
Aiming at solving the problem of strong coupling characteristic of the key parameters of high-speed pneumatic pulse width modulation( PWM) on / off valve, a general lumped parameter mathematical model based on the val...Aiming at solving the problem of strong coupling characteristic of the key parameters of high-speed pneumatic pulse width modulation( PWM) on / off valve, a general lumped parameter mathematical model based on the valves time periods was well developed. With this model,the mass flow rate and dynamic pressure characteristics of constant volumes controlled by high-speed pneumatic PWM on /off valves was well described. A variable flow rate coefficient model was proposed to substitute for the constant one used in most of the prior works to investigate PWM on /off valves' dynamical pressure response, and a formula for disclosing the inherent relationship among the PWM command signal,static mass flow rate,and sonic conductance of the valve was newly derived.Finally,an extensive set of analytical experimental comparisons were implemented to verify the validity of the proposed mathematica model. With the proposed model, PWM on /off valves' characteristics,such as mass flow rate,step pressure response of the valve control system,mean pressure and ripple amplitude,not only in the linear range,but also in the nonlinear range can be wel predicted; Good agreement between measured and calculated results was obtained,which proved that the model is helpful for designing a control strategy in a closed loop control system.展开更多
It is adopted the single-diode solar cell model and extended for a PV module. The current vs. voltage (I-V) characteristic based on the Lambert W-function was used. The estimation parameters for the simulation approac...It is adopted the single-diode solar cell model and extended for a PV module. The current vs. voltage (I-V) characteristic based on the Lambert W-function was used. The estimation parameters for the simulation approach of the photovoltaic (PV) module make use of Levenberg-Marquardt method. It was considered an industrial polycrystalline silicon photovoltaic (PV) module and the simulated results were compared with the experimental ones extracted from a specific datasheet. The I-V characteristic for the analysed PV module and its maximum output power are investigated for different operating conditions of incident solar radiation flux and temperature, as well as parameters related to the solar cells material and technology (series resistance, shunt resistance and gamma factor). The analysis gives indications and limitations for design and optimization of the performance for industrial PV modules. This study can be implemented in any type of PV module.展开更多
Solid-state batteries(SSBs) with high safety are promising for the energy fields,but the development has long been limited by machinability and interfacial problems.Hence,self-supporting,flexible Nano LLZO CSEs are pr...Solid-state batteries(SSBs) with high safety are promising for the energy fields,but the development has long been limited by machinability and interfacial problems.Hence,self-supporting,flexible Nano LLZO CSEs are prepared with a solvent-free method at 25℃.The 99.8 wt% contents of Nano LLZO particles enable the Nano LLZO CSEs to maintain good thermal stability while exhibiting a wide electrochemical window of 5.0 V and a high Li~+ transfer number of 0.8.The mean modulus reaches 4376 MPa.Benefiting from the interfacial modulation,the Li|Li symmetric batteries based on the Nano LLZO CSEs show benign stability with lithium at the current densities of 0.1 mA cm^(-2),0.2 mA cm^(-2),and 0.5 mA cm^(-2).In addition,the Li|LiFePO_(4)(LFP) SSBs achieve favorable cycling performance:the specific capacity reaches128.1 mAh g^(-1) at 0.5 C rate,with a capacity retention of about 80% after 600 cycles.In the further tests of the LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811) cathodes with higher energy density,the Nano LLZO CSEs also demonstrate good compatibility:the specific capacities of NCM811-based SSBs reach 177.9 mAh g^(-1) at 0.5 C rate,while the capacity retention is over 96% after 150 cycles.Furthermore,the Li|LFP soft-pack SSBs verify the safety characteristics and the potential for application,which have a desirable prospect.展开更多
The characteristic tilting modules of quasi-hereditary algebras which are dual extensions of directed monomial algebras are explicitly constructed; and it is shown that the Ringel dual of the dual extension of an arbi...The characteristic tilting modules of quasi-hereditary algebras which are dual extensions of directed monomial algebras are explicitly constructed; and it is shown that the Ringel dual of the dual extension of an arbitrary hereditary algebra has triangular decomposition and bipartite quiver.展开更多
Silicone gel is a prevailing material for encapsulation in insulated gate bipolar transistor(IGBT)power modules.The space charge transport behavior in silicone gel is significant to evaluate the electrical insulation ...Silicone gel is a prevailing material for encapsulation in insulated gate bipolar transistor(IGBT)power modules.The space charge transport behavior in silicone gel is significant to evaluate the electrical insulation characteristics.This paper focuses on the trap characteristics and electrical properties of the silicone gel,which were rarely studied before.The experiments are performed on the surface potential decay of silicone gel after the charge injection.Then,the energy distributions of electron or hole traps are determined by a double-trap energy level model,which can be fitted by the Gaussian distribution.In addition,the mobilities of positive and negative charges are determined,which are 1.38×10^(-12) m^(2)·V^(-1)·s^(-1) and 1.74×10^(12) m^(2)·V^(-1)·s^(-1),respectively.Furthermore,considering the heat as a byproduct resulting in thermal issues,the temperature-dependence of surface potential decay characteristics are also studied in this paper.When temperature rises,the decay rate of surface potential increases,especially when the temperature is higher than 80℃.Finally,the contrastive analysis illustrates that the trap characteristics of silicone gel are between the trap characteristics in liquid-state material and solid-state material,which supports the phenomenon that silicone gel is more resistive to the sharp edges in power modules.This work can provide a useful reference for the design of encapsulation in high-voltage IGBT power modules.展开更多
Associated with each finite directed quiver Q is a quasi-hereditary algebra. the so-called twisted double of the path algebra kQ. Characteristic tilting modules over this class of quasi-hereditary algebras are constru...Associated with each finite directed quiver Q is a quasi-hereditary algebra. the so-called twisted double of the path algebra kQ. Characteristic tilting modules over this class of quasi-hereditary algebras are constructed. Their endonorphism algebras are explicitly described. It turns out that this class of quasi-hereditary algebras is closed under taking the Ringel dual.展开更多
基金supported by National Natural Science Foundation of China(Nos.10972145,11272218,11472178)Program for Liaoning Excellent Talents in University of China(No.LR2013008)Open Foundation of Key Laboratory of Liaoning Weapon Science and Technology,Liaoning Province Talents Engineering Projects of China(No.2012921044)
文摘To researching the damage characteristics of typical logical chip modules in spacecraft due to plasma generated by hypervelocity impacts,we have established a triple Langmuir probe diagnostic system and a logical chips measurement system,which were used to diagnose plasma characteristic parameters and the logical chip module＇s logical state changes due to the plasma created by a 7075 aluminum projectile hypervelocity impact on the 2A12 aluminum target.Three sets of experiments were performed with the collision speeds of 2.85 km/s,3.1 km/s and2.20 km/s,at the same incident angles of 30 degrees and logical chip module＇s positions by using a two-stage light gas gun loading system,a plasma characteristic parameters diagnostic system and a logical chip module＇s logical state measurement system,respectively.Electron temperature and density were measured at given position and azimuth,and damage estimation was performed for the logical chip module by using the data acquisition system.Experimental results showed that temporary damage could be induced on logical chip modules in spacecraft by plasma generated by hypervelocity impacts under the given experimental conditions and the sensors＇ position and azimuth.
基金supported by the National Key R&D Program of China (grant no. 2017YFB0903303)
文摘High-temperature,high-power converters have gained importance in industrial applications given their ability to operate in adverse environments,such as in petroleum exploration,multi-electric aircrafts,and electric vehicles.SiC metaloxide-semiconductor field-effect transistor(MOSFET),a new,wide bandgap,high-temperature device,is the key component of these converters.In this study,the static and dynamic characteristics of the SiC MOSFET,half-bridge module,are investigated at the junction temperature of 180℃.A simplified experimental method is then proposed pertaining to the power operation of the SiC module at 180℃.This method is based on the use of a thermal resistance test platform and is proven convenient for the study of heat dissipation characteristics.The high-temperature characteristics of the module are verified based on the conducted experiments.Accordingly,a 100 kW high-temperature converter is built,and the test results show that the SiC converter can operate at a junction temperature of 180℃in a stable manner in compliance with the requirements of high-temperature,high-power applications.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.51573006,51573003,51203003,51303008,51302006,51402006,51272026,and 51273022)the Major Project of Beijing Science and Technology Program,China(Grant Nos.Z151100003315023 and Z141100003814011)the Fok Ying Tung Education Foundation,China(Grant No.142009)
文摘Cholesteric liquid crystals（CLCs） have recently sparked an enormous amount of interest in the development of soft matter materials due to their unique ability to self-organize into a helical supra-molecular architecture and their excellent selective reflection of light based on the Bragg relationship.Nowadays,by the virtue of building the self-organized nanostructures with pitch gradient or non-uniform pitch distribution,extensive work has already been performed to obtain CLC films with a broad reflection band.Based on authors＇ many years＇ research experience,this critical review systematically summarizes the physical and optical background of the CLCs with broadband reflection characteristics,methods to obtain broadband reflection of CLCs,as well as the application in the field of intelligent optical modulation materials.Combined with the research status and the advantages in the field,the important basic and applied scientific problems in the research direction are also introduced.
文摘This paper conducts a research on modulation characteristics of blue light-emitting diodes (LEDs) used in a visible-light communication (VLC) system. Through analysis of the modulation characteristics of LEDs with different emitting sizes, we find that there is a similar linear relationship between LED’s 3dB bandwidth and the operation current density. This experiment also shows that high series resistance is one major issue that limits our LED's modulation speed. To further improve the LED bandwidth, the resistance can be reduced by optimizing device layout as well as reducing material bulk resistance. Clearly, this study provides an approach to increase the modulation bandwidth of GaN-based LEDs for VLC systems.
基金financially supported by the Young Elite Scientist Sponsorship Program by CAST ( 2018QNRC001)the China Postdoctoral Science Foundation ( 2018M631172)
文摘It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enhanced the secretion of MSC-derived exosomes with stronger anti-inflammatory protein,cytokine profiles,and functional RNA via altering COX2/PGE2 pathway.Recently,accumulating evidence has also revealed that biophysical cues(especially biomechanical cues)in cell microenvironment have significant effects not only on cells but also on their exosomes.It has been reported that applying bi-axial strain to MSCs induces formation of a stiffer cytoskeleton through mTORC2 signaling,which biases against adipogenic differentiation and toward osteoblastogenesis.At the same time,For example,dimensionality,composition and stiffness of the extracellular matrix(ECM)has been proved to affect the size and composition of exosomes secreted by cancer cells.However,the effects of biomechanical cues in the three-dimensional(3D)microenvironment on stem cell-derived exosomes remains to be unveiled.Therefore,it is important to understand the roles of 3D cell mechanical microenvironment in regulating the characteristics of stem cell-derived exosomes and develop more efficient approaches to enhance their functions.This study aimed to explore the changes in characteristics of exosomes secreted by MSCs in periodontium in response to the matrix strain in 3D.Periodontal ligament stem cells(PDLSCs)were cultured in a 3D strain microenvironment engineered with microscale magnetically stretched collagen hydrogels.The morphology,particle distribution,marker protein expression of PDLSC-derived exosomes were analyzed.Then the pro-osteogenic property of exosomes was evaluated by assessing cell viability,proliferation,migration and osteogenic differentiation of target cells,for instance human bone marrow mesenchymal stem cells(hBMSCs).Detailed characterizations revealed that PDLSC-derived exosomes in the 3D strain mi-croenvironment were with similar morphology,particle distribution and surface markers.Notably,Exosomes secreted by PDLSCs in strain microenvironment were more endocytosed by hBMSCs and were more potent in improving proliferation and migration of hBMSCs,comparing with PDLSCs in non-strain environment.Alizarin red staining and molecular biology experiments confirmed that treatment of exosomes secreted by PDLSCs under mechanical stimulation led to a significant increase in osteogenic differentiation of hBMSCs in vitro.Meanwhile,in vivo study also indicated that PDLSC-derived exosomes obtained from the 3D strain microenvironment could obviously promote new bone formation.Our findings revealed that mechanical cues profoundly affected the characteristics of PDLSC-derived exosomes,especially for their bio-activity,providing a foundation for using the 3D mechanical microenvironment to enhance the osteo-inductive functions of stem cell-derived exosomes in cell-free therapy for bone regeneration.
文摘Based on the scattering characteristic,the comparison of RCS(radar cross-section)at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the entity.A simulation method of aerial&space targets echo characteristics(A&STEC)is proposed that is universal to aerial and space targets.We utilize a fixed-wing UAV(unmanned aerial vehicle)and typical missiles in simulation.The echo signal modulation characteristic parameters are calculated theoretically by the atmospheric attenuation model,the finite element method and a MUMPS solver.The verification simulations show that this method can analyze the influence of the target shape,incident direction,detection position and detection frequency on echo waveform,intensity and energy distribution.The results show that the profile of echo waveform can invert the general shape of the target.The relationship between time and intensity can determine whether the target is moving towards or away from the detector in addition.These conclusions can provide a reference for the ballistic missile target tracking and the defense against UVA intrusion in theory.
基金supported by the National Key Research and Development Program of China(No.2019YFB2004502)the National Natural Science Foundation of China(No.51975397)the Key Research and Development Program of Shanxi Province(No.201903D111007),China。
文摘The electrical modulation valve can provide proportional output valve element displacement,flow,or pressure according to a continuously changing input electrical signal.It is the core component of electro-hydraulic proportional control technology.To remove the influence of pressure difference changes on the output flow,the traditional scheme is to use a pressure compensation valve,which increases the difficulty of both manufacturing and maintaining the valve.To solve this problem,a method of digital and mechanical redundancy control flow is proposed.Pressure sensors are installed at the inlet and outlet of the valve,and the controller adjusts the displacement of the valve element according to the pressure difference between the valve ports to realize high-precision control of the flow.A pressure compensation valve is installed in front of the valve,and a three-way solenoid valve is used to control the working of the compensation valve.In the case of sensor failure,the valve is switched to the mechanical compensation differential pressure mode,to control the flow and to achieve redundancy control.The system security is thereby improved.The feasibility of this scheme is verified through simulation and tests.The results show that,both for digital compensation and mechanical compensation,the output flow can be kept constant when the pressure difference changes,and the system has good static and dynamic characteristics.The principle can be applied to the displacement-flow feedback type electrical modulation valve,and can realize accurate control of the flow of the pilot valve and,finally,accurate control of the flow in the main valve.
基金Supported by the National Key Research and Development Program of China under Grant No 2016YFB0402302the National Natural Science Foundation of China under Grant No 91433206
文摘Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-signal modulation characteristics of the simultaneous ground-state （GS） and the excited-state （ES） lasing in InAs/OaAs quantum dot laser diodes. The large-signal modulation capability of total light intensity in the transition regime from OS lasing to two-state lasing is unchanged as the bias-current increases. However, GS and ES large-signal eye diagrams show obvious variations during the transition. Relaxation oscillations and large-signal eye diagrams for OS, ES, and total light intensities are numerically simulated and analyzed in detail by using a rate-equation model. The -ndings show that a complementary relationship between the light intensities for OS and ES lasing exists in both the transition regime and the two-state lasing regime, leading to a much smaller overshooting power and a shorter settling time for the total light intensity. Therefore, the eye diagrams of GS or ES lasing are diffuse whereas those of total light intensity are constant as the bias-current increases in the transition regime.
文摘To reduce thrust ripple and cost and improve the average thrust of permanent magnet linear motors,a modular dual-field modulation permanent magnet linear motor was studied,and the parameters were optimized.First,sensitive parameters were selected using the Taguchi method,and then the optimal variables were sampled using the optimal Latin hypercube experimental design method and an ensemble of surrogates model of optimization objectives,and its accuracy was verified.Next,a multi-objective particle swarm optimization algorithm was used to optimize the purpose of“maximum average thrust and minimum thrust ripple”,and the Pareto front of average thrust and thrust ripple was obtained.Finite element analysis showed that the optimized modular dual flux-modulation permanent magnet linear motor(MDFMPMLM)had a 29.5%reduction in thrust ripple and a 5%increase in average thrust compared to the original motor.This study provided an effective method for improving the performance of permanent magnet linear motors.
文摘Natural properties of high speed on-off valves can be described through their on-off behavior and spool movement (static and oscillating) characteristics. High speed on-off valves can be combined with actuators in systems into four typical types of composite valves whose static characteristics are related not only to the structures of the single valves and the composite ones, but also to the PWM control modes. It is proved that the composite valves have similar features as those of servo valves. The nonlinear specific properties of single valves composited can be completely compensated by the suitable PWM control modes.
基金supported by High Technology Research and Development Program of China(No.2006AA06A101).
文摘A numerical model and transmission characteristic analysis of DPSK （differential phase shift keying） pressure signals in mud channels is introduced. With the control logic analysis of the rotary valve mud telemetry, a logical control signal is built from a Gate function sequence according to the binary symbols of transmitted data and a phase-shift function is obtained by integrating the logical control signal. A mathematical model of the DPSK pressure signal is built based on principles of communications by modulating carrier phase with the phase-shift function and a numerical simulation of the pressure wave is implemented with the mathematical model by MATLAB programming. Considering drillpipe pressure and drilling fluid temperature profile along drillpipes, the drillpipe of a vertical well is divided into a number of sections. With water-based drilling fluids, the impacts of travel distance, carrier frequency, drillpipe size, and drilling fluids on the signal transmission were studied by signal transmission characteristic analysis for all the sections. Numerical calculation results indicate that the influences of the viscosity of drilling fluids and volume fraction of gas in drilling fluids on the DPSK signal transmission are more notable than the others and the signal will distort in waveform with differential attenuations of the signal frequent component.
基金supported by National Natural Science Foundation of China(Nos.11475103,21627812)the National Key Research and Development Program of China(No.2016YFD0102106)Tsinghua University Initiative Scientific Program(20161080108)
文摘Cold atmospheric plasma(CAP)jet has wide applications in various fields including advanced materials synthesis and modifications,biomedicine,environmental protection and energy saving,etc.Appropriate control on the volume,temperature and chemically reactive species concentratio ns of the CAP jet is of great importance in actual applications.In this paper,an radio-frequency atmospheric-pressure glow discharge(RF-APGD)plasma generator with a hybrid cross-linear-field electrode configuration is proposed.The experimental results show that,with the aid of the copper mesh located at the downstream of the traditional co-axial-type plasma generator with a cross-field electrode configuration,a linear field between the inner powered electrode of the traditional plasma generator and the copper mesh can be established.This linerfield can,to some extent,enhance the discharges at the upstream of the copper mesh,resulting in small increments(all less than 12.5%)of the species emission intensities,electron excitation temperatures and gas temperatures by keeping other parameters being unchanged.And due to the intrinsic transparent and conducting features of the grounded copper mesh to the gas flowing,electric current and heat flux of the plasma plumes,a plasma region with higher concentrations of chemically reactive species and larger plasma plume diameters is obtained at the downstream of the grounded copper mesh on the same level of the gas temperature and electron excitation temperature compared to those of the plasma free jet.In addition,the charged particle number densities at the same downstream axial location of the grounded copper mesh decrease significantly compared to those of the plasma free jet.This means that the copper mesh is also,to some extent,helpful for separating the chemically reactive neutral species from the charged particles in side a plasma environment.The preceding results indicate that the cross-linear-field electrode configuration of the plasma generator is an effective approach for tuning the characteristics of the RF-APGD plasma jet in order to obtain an appropriate combination of the plasma jet properties with higher chemically reactive species concentrations,especially relative higher number densities of neutral species,larger plasma volumes and lower gas temperatures.
基金National Natural Science Foundation of China(No.51205362)Zhejiang Provincial National Science Foundation of China(No.LQ12E05017)
文摘Aiming at solving the problem of strong coupling characteristic of the key parameters of high-speed pneumatic pulse width modulation( PWM) on / off valve, a general lumped parameter mathematical model based on the valves time periods was well developed. With this model,the mass flow rate and dynamic pressure characteristics of constant volumes controlled by high-speed pneumatic PWM on /off valves was well described. A variable flow rate coefficient model was proposed to substitute for the constant one used in most of the prior works to investigate PWM on /off valves' dynamical pressure response, and a formula for disclosing the inherent relationship among the PWM command signal,static mass flow rate,and sonic conductance of the valve was newly derived.Finally,an extensive set of analytical experimental comparisons were implemented to verify the validity of the proposed mathematica model. With the proposed model, PWM on /off valves' characteristics,such as mass flow rate,step pressure response of the valve control system,mean pressure and ripple amplitude,not only in the linear range,but also in the nonlinear range can be wel predicted; Good agreement between measured and calculated results was obtained,which proved that the model is helpful for designing a control strategy in a closed loop control system.
基金This research was conducted under the research project“High-performance tandem heterojunction solar cells for specific applications(SOLHET)”,funded by the Research Council of Norway(RCN),project no.251789 the Romanian Executive Agency for Higher Education,Research,Development and Innovation Funding(UEFISCDI),project no.34/2016 and 35/2016,through the M-Era.net program.
文摘It is adopted the single-diode solar cell model and extended for a PV module. The current vs. voltage (I-V) characteristic based on the Lambert W-function was used. The estimation parameters for the simulation approach of the photovoltaic (PV) module make use of Levenberg-Marquardt method. It was considered an industrial polycrystalline silicon photovoltaic (PV) module and the simulated results were compared with the experimental ones extracted from a specific datasheet. The I-V characteristic for the analysed PV module and its maximum output power are investigated for different operating conditions of incident solar radiation flux and temperature, as well as parameters related to the solar cells material and technology (series resistance, shunt resistance and gamma factor). The analysis gives indications and limitations for design and optimization of the performance for industrial PV modules. This study can be implemented in any type of PV module.
基金supported by Science and Technology Project of China Southern Power Grid (SZKJXM20230049/090000KC23010038)。
文摘Solid-state batteries(SSBs) with high safety are promising for the energy fields,but the development has long been limited by machinability and interfacial problems.Hence,self-supporting,flexible Nano LLZO CSEs are prepared with a solvent-free method at 25℃.The 99.8 wt% contents of Nano LLZO particles enable the Nano LLZO CSEs to maintain good thermal stability while exhibiting a wide electrochemical window of 5.0 V and a high Li~+ transfer number of 0.8.The mean modulus reaches 4376 MPa.Benefiting from the interfacial modulation,the Li|Li symmetric batteries based on the Nano LLZO CSEs show benign stability with lithium at the current densities of 0.1 mA cm^(-2),0.2 mA cm^(-2),and 0.5 mA cm^(-2).In addition,the Li|LiFePO_(4)(LFP) SSBs achieve favorable cycling performance:the specific capacity reaches128.1 mAh g^(-1) at 0.5 C rate,with a capacity retention of about 80% after 600 cycles.In the further tests of the LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811) cathodes with higher energy density,the Nano LLZO CSEs also demonstrate good compatibility:the specific capacities of NCM811-based SSBs reach 177.9 mAh g^(-1) at 0.5 C rate,while the capacity retention is over 96% after 150 cycles.Furthermore,the Li|LFP soft-pack SSBs verify the safety characteristics and the potential for application,which have a desirable prospect.
文摘The characteristic tilting modules of quasi-hereditary algebras which are dual extensions of directed monomial algebras are explicitly constructed; and it is shown that the Ringel dual of the dual extension of an arbitrary hereditary algebra has triangular decomposition and bipartite quiver.
基金This work was supported by the National Natural Science Foundation of China-the State Grid Corporation Joint Fund for Smart Grid(U1766219)the Fundamental Research Funds for the Central Universities(2019QN120).
文摘Silicone gel is a prevailing material for encapsulation in insulated gate bipolar transistor(IGBT)power modules.The space charge transport behavior in silicone gel is significant to evaluate the electrical insulation characteristics.This paper focuses on the trap characteristics and electrical properties of the silicone gel,which were rarely studied before.The experiments are performed on the surface potential decay of silicone gel after the charge injection.Then,the energy distributions of electron or hole traps are determined by a double-trap energy level model,which can be fitted by the Gaussian distribution.In addition,the mobilities of positive and negative charges are determined,which are 1.38×10^(-12) m^(2)·V^(-1)·s^(-1) and 1.74×10^(12) m^(2)·V^(-1)·s^(-1),respectively.Furthermore,considering the heat as a byproduct resulting in thermal issues,the temperature-dependence of surface potential decay characteristics are also studied in this paper.When temperature rises,the decay rate of surface potential increases,especially when the temperature is higher than 80℃.Finally,the contrastive analysis illustrates that the trap characteristics of silicone gel are between the trap characteristics in liquid-state material and solid-state material,which supports the phenomenon that silicone gel is more resistive to the sharp edges in power modules.This work can provide a useful reference for the design of encapsulation in high-voltage IGBT power modules.
基金Supported partially by Alexander von Humboldt FoundationNational Natural Science Foundation of China (Grant No. 19971009).
文摘Associated with each finite directed quiver Q is a quasi-hereditary algebra. the so-called twisted double of the path algebra kQ. Characteristic tilting modules over this class of quasi-hereditary algebras are constructed. Their endonorphism algebras are explicitly described. It turns out that this class of quasi-hereditary algebras is closed under taking the Ringel dual.
