Congenital myopathies are a group of minimally progressive or non-progressive neuromuscular conditions which is present from birth. A classical type of congenital myopathy is called central core disease. This conditio...Congenital myopathies are a group of minimally progressive or non-progressive neuromuscular conditions which is present from birth. A classical type of congenital myopathy is called central core disease. This condition is often confused with muscular dystrophy. Central core disease can be associated with comorbidities which affect pregnancy and its management. In this case series, we describe two cases, who are siblings affected by the same condition but at varied levels and their management during pregnancy. We also would like to illustrate a management plan for congenital myopathy during pregnancy, for a good maternal and fetal outcome.展开更多
As a potential mineral resource, the clay minerals enriched in rare earth elements including yttrium（REY） in the deep sea have been attracting great attention. However, the enrichment mechanism of REY remains unclea...As a potential mineral resource, the clay minerals enriched in rare earth elements including yttrium（REY） in the deep sea have been attracting great attention. However, the enrichment mechanism of REY remains unclear. To understand the geochemical characteristics and factors controlling REY enrichment in zeolite clay in the deep sea, we conducted mineral identification by XRD, major and trace element measurements by XRF and REY analyses by ICP-MS on a 1.4-m-long sediment core（GC02） located in the Central Indian Oceanic Basin（CIOB）. The main findings include：（1） the core sediments in GC02 possess elevated REY contents and exhibited a strong negative Ce anomaly, an apparent MREE bulge and positive Y anomaly. These were comparable with typical REY-rich clays in the Pacific Ocean, indicating the similar REY enrichment mechanism and the presence of REY-rich clays in the CIOB;（2） in comparison with the dataset from the Wharton Basin and DSDP site 213, the higher content of REY and stronger PAAS（Post Archean Australian Shale） normalization patterns in the GC02 sediments were likely caused by the weaker impact of terrigenous materials of GC02. The CIOB was suggested to be a promising place hosting REY rich pelagic sediments.展开更多
The As-level topology is a hotspot of the recent reseaches. We can understand the centralization of the network clearly by researching the evolvement trend of the Internet macroscopic topology. The massive data we use...The As-level topology is a hotspot of the recent reseaches. We can understand the centralization of the network clearly by researching the evolvement trend of the Internet macroscopic topology. The massive data we use in this paper is from CAIDA (The Cooperative Association for Internet Data Analysis) Skitter project. And the time span of the data is from July, 2001 to January, 2008. This paper introduces the background of the AS-level topology at first, then carries out the evolvement of degree, core and layer. It is believed that the influence of the top-degree nodes on the other nodes decreases and the centralization of network is going to fall off with the decrease of the core. And the nucleus status of network declines.展开更多
The Kathmandu valley is an intermountain basin located at about 1300 and surounded by mountains around 2400m.Thick fluvio\|lacustrine sediments from late Pliocene to Quaternary are accumulated there under monsoon clim...The Kathmandu valley is an intermountain basin located at about 1300 and surounded by mountains around 2400m.Thick fluvio\|lacustrine sediments from late Pliocene to Quaternary are accumulated there under monsoon climate.We undertook palynological and sedimentological studies on 284\|m\|long drilled core that reaches the basement of the kathmandu basin,in order to clarify the paleoclimatic changes and their tectonic link with uplifting of the Himalayas..The core is lithologically divided into three members:sand predominant lower member (51m),slit and clay dominant middle member (182m) and organic silty clay predominant upper member (45m).We analyzed fossil pollens contained in muddy samples which were taken from the middle and upper member in every one meter interval.The pollen assemblage is characterized by predominance of \%Quercus,\%30%～80% of the all arboreal pollen.We inferred paleoclimatic changes on the basis of comparison between present vegetation and climate of Kathmandu valley and surrounded mountains and pollen diagram which we obtained.For the purpose of inference of paleoclimate,we used the following genera as climatic index:\%Pinus\% for cold climate, \%Quercus\% and \%Cyclobalanopsis\% for warm climate, Alnus for wet climate and Gramineae for dry climate.As the reference.we also examined amount of another eight genera,two family and all spores.The pollen diagram shows two pattern of paleoclimatic changes:oscillation pattern with seven times fluctuation of warm and cold climate in younger period (ca.115m in depth),and older less fluctuated pattern of warm climate.During the older period (209～215m in depth),one cold stage was recognized,and is characterized by predominance of Pinus and occurrence of Tsuga .展开更多
文摘Congenital myopathies are a group of minimally progressive or non-progressive neuromuscular conditions which is present from birth. A classical type of congenital myopathy is called central core disease. This condition is often confused with muscular dystrophy. Central core disease can be associated with comorbidities which affect pregnancy and its management. In this case series, we describe two cases, who are siblings affected by the same condition but at varied levels and their management during pregnancy. We also would like to illustrate a management plan for congenital myopathy during pregnancy, for a good maternal and fetal outcome.
基金supported by the National Natural Science Foundation of China(41773005)China Ocean Mineral Resources R&D Association(COMRA)Research Program(DY125-11-R-01,DY125-22-02),the Research Center for Air Pollution and Health(RCAPH)of Zhejiang University
文摘As a potential mineral resource, the clay minerals enriched in rare earth elements including yttrium（REY） in the deep sea have been attracting great attention. However, the enrichment mechanism of REY remains unclear. To understand the geochemical characteristics and factors controlling REY enrichment in zeolite clay in the deep sea, we conducted mineral identification by XRD, major and trace element measurements by XRF and REY analyses by ICP-MS on a 1.4-m-long sediment core（GC02） located in the Central Indian Oceanic Basin（CIOB）. The main findings include：（1） the core sediments in GC02 possess elevated REY contents and exhibited a strong negative Ce anomaly, an apparent MREE bulge and positive Y anomaly. These were comparable with typical REY-rich clays in the Pacific Ocean, indicating the similar REY enrichment mechanism and the presence of REY-rich clays in the CIOB;（2） in comparison with the dataset from the Wharton Basin and DSDP site 213, the higher content of REY and stronger PAAS（Post Archean Australian Shale） normalization patterns in the GC02 sediments were likely caused by the weaker impact of terrigenous materials of GC02. The CIOB was suggested to be a promising place hosting REY rich pelagic sediments.
文摘The As-level topology is a hotspot of the recent reseaches. We can understand the centralization of the network clearly by researching the evolvement trend of the Internet macroscopic topology. The massive data we use in this paper is from CAIDA (The Cooperative Association for Internet Data Analysis) Skitter project. And the time span of the data is from July, 2001 to January, 2008. This paper introduces the background of the AS-level topology at first, then carries out the evolvement of degree, core and layer. It is believed that the influence of the top-degree nodes on the other nodes decreases and the centralization of network is going to fall off with the decrease of the core. And the nucleus status of network declines.
文摘The Kathmandu valley is an intermountain basin located at about 1300 and surounded by mountains around 2400m.Thick fluvio\|lacustrine sediments from late Pliocene to Quaternary are accumulated there under monsoon climate.We undertook palynological and sedimentological studies on 284\|m\|long drilled core that reaches the basement of the kathmandu basin,in order to clarify the paleoclimatic changes and their tectonic link with uplifting of the Himalayas..The core is lithologically divided into three members:sand predominant lower member (51m),slit and clay dominant middle member (182m) and organic silty clay predominant upper member (45m).We analyzed fossil pollens contained in muddy samples which were taken from the middle and upper member in every one meter interval.The pollen assemblage is characterized by predominance of \%Quercus,\%30%～80% of the all arboreal pollen.We inferred paleoclimatic changes on the basis of comparison between present vegetation and climate of Kathmandu valley and surrounded mountains and pollen diagram which we obtained.For the purpose of inference of paleoclimate,we used the following genera as climatic index:\%Pinus\% for cold climate, \%Quercus\% and \%Cyclobalanopsis\% for warm climate, Alnus for wet climate and Gramineae for dry climate.As the reference.we also examined amount of another eight genera,two family and all spores.The pollen diagram shows two pattern of paleoclimatic changes:oscillation pattern with seven times fluctuation of warm and cold climate in younger period (ca.115m in depth),and older less fluctuated pattern of warm climate.During the older period (209～215m in depth),one cold stage was recognized,and is characterized by predominance of Pinus and occurrence of Tsuga .
