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Mesh repair of sacrococcygeal hernia via a combined laparoscopic and sacrococcygeal approach: A case report 被引量:1
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作者 Yuan-Qiang Dong Li-Jia Liu +1 位作者 Zan Fu Si-Meng Chen 《World Journal of Clinical Cases》 SCIE 2020年第2期362-369,共8页
BACKGROUND Sacrococcygeal hernia is a very rare condition that is usually secondary to sacrococcygectomy, and its ideal treatment regimen is unclear. Herein, we report a case of sacrococcygeal hernia occurring in a pa... BACKGROUND Sacrococcygeal hernia is a very rare condition that is usually secondary to sacrococcygectomy, and its ideal treatment regimen is unclear. Herein, we report a case of sacrococcygeal hernia occurring in a patient who had no history of sacrococcygeal operation, present the operative procedures of mesh repair via a combined laparoscopic and sacrococcygeal approach that has not been described,and discuss our experience in diagnosis and treatment with a review of the literature.CASE SUMMARY A 54-year-old woman who chiefly complained of a 10-year history of a reversible bulge in her right sacrococcygeal region was admitted to our hospital. The physical examination revealed a bulge in the right sacrococcygeal region upon standing, which disappeared in the prone position but relapsed when performing the Valsalva manoeuvre. Computed tomography displayed an abnormality in the structure of the tissues between the midline of the sacrococcygeal region and the right gluteus muscle. The patient was diagnosed with sacrococcygeal hernia and received hernia repair with mesh through a combined laparoscopic and sacrococcygeal approach. On laparoscopy, the rectum was dissected posterolaterally, and a defect was identified in the right anterior sacrococcygeal region through which part of the rectum protruded. This was followed by the placement of a self-gripping polyester mesh via a sacrococcygeal approach. There were no postoperative complications. The patient was discharged on postoperative day 7 and was followed for more than 6 mo with no recurrence.CONCLUSION Laparoscopic mesh repair is recommended as a priority of surgical options for sacrococcygeal hernias, while choosing a self-gripping mesh can help avoid the risk of presacral vessel injury by reducing suture fixation. 展开更多
关键词 Sacrococcygeal region HERNIA Mesh repair Surgical approach LAPAROSCOPY case report
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A Case Study of TESOL Approaches in Australia and Its Implication
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作者 马之成 《海外英语》 2017年第3期235-238,共4页
Based on a case study of TESOL approaches applied in several Australian institutions,this paper gives critical analysis of the approaches by comparing them with the one encountered in the situation in which the author... Based on a case study of TESOL approaches applied in several Australian institutions,this paper gives critical analysis of the approaches by comparing them with the one encountered in the situation in which the author has been working.A further implication of those approaches is also examined. 展开更多
关键词 case study TESOL approaches in Australia IMPLICATION
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Successful minimal approach transcatheter aortic valve replacement in an allograft heart recipient 19 years post transplantation for severe aortic stenosis: A case report
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作者 Sravani Avula Sudhir Mungee Marco A Barzallo 《World Journal of Cardiology》 CAS 2019年第8期209-212,共4页
BACKGROUND Aortic stenosis is one of the rare valvular complications in a transplanted heart.Over the past 8 years,transcatheter approach for aortic valve replacement(TAVR)has been slowly evolving to be the preferred ... BACKGROUND Aortic stenosis is one of the rare valvular complications in a transplanted heart.Over the past 8 years,transcatheter approach for aortic valve replacement(TAVR)has been slowly evolving to be the preferred approach in these patient population when compared to the surgical approach.We report a second case in the United States with successful transfemoral minimal approach with minimal sedation for TAVR in a heart transplant recipient 19 years post transplantation for severe symptomatic calcified aortic stenosis.CASE SUMMARY We present a case of 73-year-old male who has undergone successful minimal approach transcatheter aortic valve replacement in an allograft heart.Patient had received orthotopic heart transplantation 19 years ago for non-ischemic cardiomyopathy.Follow up transthoracic echocardiograms as per routine protocol did not show any aortic valve disease until 15 years post transplantation.Aortic valve was noted to be mildly sclerotic at that time and gradually progressed to severe symptomatic aortic stenosis over the next 4 years.Patient had complaints of worsening shortness of breath that limited his functional capacity.Overall his post heart transplantation period has been mostly uneventful except for allograft non occlusive vasculopathy and aortic stenosis.His Society of Thoracic Surgery risk score was 12.205%and he was considered to be a high-risk surgical candidate by surgeon.Decision was made to undergo transcatheter aortic valve replacement.CONCLUSION With the improved survival of these patients,we think it is time to look intopathophysiology of valvular disease in transplant heart recipients.Some other unanswered questions include,underlying donor and recipient risk factors for valvular diseases in heart transplant recipients. 展开更多
关键词 Transcatheter AORTIC VALVE REPLACEMENT HEART transplant MINIMAL approach VALVE REPLACEMENT Severe AORTIC stenosis case report
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Recurrent aggressive mesenteric desmoid tumor successfully treated with sorafenib: A case report and literature review 被引量:4
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作者 Aikaterini Mastoraki Dimitrios Schizas +7 位作者 Chrysovalantis Vergadis Leon Naar Alexios Strimpakos Michail G Vailas Natasha Hasemaki George Agrogiannis Theodore Liakakos Nikolaos Arkadopoulos 《World Journal of Clinical Oncology》 CAS 2019年第4期183-191,共9页
BACKGROUND Desmoid tumors(DT) are locally advanced but histologically benign monoclonal neoplasms that can occur from any musculoaponeurotic structure. The aim of this report is to analyze a rare clinical case of an a... BACKGROUND Desmoid tumors(DT) are locally advanced but histologically benign monoclonal neoplasms that can occur from any musculoaponeurotic structure. The aim of this report is to analyze a rare clinical case of an aggressive intra-abdominal DT successfully treated with sorafenib.CASE SUMMARY A 36-year-old man presented with increasing colicky abdominal pain and a selfpalpable mass in his left abdomen. Fourteen years earlier he was diagnosed with a large intra-abdominal tumor, which adhered to the left colonic flexure, part of the major gastric curvature and the spleen. Subsequent exploratory laparotomy revealed a voluminous mass in the epigastrium, arising from the posterior surface of the stomach and invading the superior mesenteric vessels, transverse mesocolon and the small bowel mesentery. As the tumor was unresectable, a jejunojejunal bypass was performed. Traditional therapeutic interventions proved insufficient, and the patient was started on sorafenib with a subsequent fulldisease response.CONCLUSIONDT's pathogenesis has been associated with mutations in the adenomatous polyposis coli(APC) gene or beta-catenin gene CTNNB1, sex steroids or previous surgical trauma. Local treatment modalities, such as surgery or radiotherapy, are implemented in aggressively progressing or symptomatic patients. Sorafenib is a hopeful therapeutic option against DTs, while several pharmacological agents have been successfully used. 展开更多
关键词 DESMOID tumor AGGRESSIVE FIBROMATOSIS case report PATHOGENESIS Therapeutic approach SORAFENIB treatment
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Brachiocephalic artery stenting through the carotid artery: A case report and review of the literature 被引量:2
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作者 Fang Xu Feng Wang Yong-Sheng Liu 《World Journal of Clinical Cases》 SCIE 2019年第17期2644-2651,共8页
BACKGROUND As the population ages and people’s living standards gradually improve,the incidence of cerebrovascular disease in China is increasing annually,posing a serious threat to people’s health.The incidence of ... BACKGROUND As the population ages and people’s living standards gradually improve,the incidence of cerebrovascular disease in China is increasing annually,posing a serious threat to people’s health.The incidence of brachiocephalic artery stenosis in ischemic cerebrovascular disease is relatively low,accounting for 0.5% to 2% of patients,but its consequences are very serious.Herein,we report a case of brachiocephalic artery stenting through the carotid artery.CASE SUMMARY The patient was a 66-year-old man.He came to our hospital because of repeated dizziness and was diagnosed with ischemic cerebrovascular disease (stenosis at the beginning of the brachiocephalic artery).Cerebral angiography suggested that the stenosis of the brachiocephalic artery had almost occluded it.Contrast agent threaded a line through the stenosis,and there was reversed blood flow through the right vertebral artery to compensate for the subclavian steal syndrome in the right subclavian artery.To improve the symptoms,we placed an Express LD (8 mm × 37 mm) balloon expanding stent in the stenosis section.After the operation,the patient’s dizziness significantly improved.However,after 6 mo,the patient was re-admitted to the hospital due to dizziness.A computed tomography scan of the head revealed multiple cerebral infarctions in bilateral basal ganglia and the right lateral ventricle.An auxiliary examination including computerized tomography angiography of the vessels of the head and cerebral angiography both showed severe stenosis in the brachiocephalic artery stent.During the operation,the guidewire and catheter were matched to reach the opening of the brachiocephalic artery.Therefore,we decided to use a right carotid artery approach to complete the operation.We sutured the neck puncture point with a vascular stapler and then ended the operation.After the operation,the patient recovered well,his symptoms related to dizziness disappeared,and his right radial artery pulsation could be detected.CONCLUSION In patients with brachial artery stenosis,when the femoral artery approach is difficult,the carotid artery is an unconventional but safe and effective approach.At the same time,the use of vascular suturing devices to suture a carotid puncture point is also commendable.Although it is beyond the published scope of the application,when used cautiously,it can effectively avoid cerebral ischemia caused by prolonged artificial compression,and improper suturing can lead to stenosis of the puncture site and improper blood pressure,resulting in the formation of a hematoma.Finally,satisfactory hemostasis can be achieved. 展开更多
关键词 STENOSIS of the brachiocephalic ARTERY Trans-carotid approach VASCULAR STAPLER case report
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A Case Retrieval Projection Pursuit Model for Configuration Design of a Product Family 被引量:1
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作者 XU Zi-rong ZHANG Yi-fei 《International Journal of Plant Engineering and Management》 2011年第3期186-192,共7页
The paper studies on case-based reasoning of uncertain product attributes in configuration design of a product family. Interval numbers characterize uncertain product attributes. By interpolating a number of certain v... The paper studies on case-based reasoning of uncertain product attributes in configuration design of a product family. Interval numbers characterize uncertain product attributes. By interpolating a number of certain values randomly to replace interval numbers and making projection pursuit analysis on source cases and target cases of expanded numbers, we can get a projection value in the optimal projection direction. Based on projection value, we can construct a case retrieval model of projection pursuit that can handle coexisting certain and uncertain product attributes. The application examples of chainsaw configuration design show that case retrieval is highly sensitive to reliable results. 展开更多
关键词 configuration design of a product family uncertain product attributes case retrieval projection pursuit approach
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Successful management of adhesion related small bowel ischemia without intestinal resection: A case report and review of literature
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作者 Pantelis Vassiliu Vasiliki Ntella +5 位作者 George Theodoroleas Zisis Mantanis Ioanna Pentara Eleni Papoutsi Aikaterini Mastoraki Nikolaos Arkadopoulos 《World Journal of Gastrointestinal Pathophysiology》 CAS 2019年第2期29-35,共7页
BACKGROUND Intraabdominal adhesions develop spontaneously or after an inflammatory process or surgical procedure in the abdomen.They are the most common cause of small bowel obstruction(SBO).SBO occasionally leads to ... BACKGROUND Intraabdominal adhesions develop spontaneously or after an inflammatory process or surgical procedure in the abdomen.They are the most common cause of small bowel obstruction(SBO).SBO occasionally leads to intestinal ischemia(In Is)which can be a life-threatening condition that requires management as soon as possible.We herein report a case of SBO with In Is presented in our institution and treated without intestinal resection.CASE SUMMARY A 34-year-old man presented at the emergency department after a 12-h-onset diffuse abdominal pain,bloating and nausea.He had a history of traumatic right hepatectomy 11 years ago as well as adhesiolysis and resection of a long part of small bowel 2 years ago.An abdominal computed tomography(CT)showed dilated loops that led to the diagnosis of SBO.Due to deteriorating lactic acidosis,the patient was operated.Torsion of the small bowel around an adhesion led to2.30 m of ischemic ileum.After the application of N/S 40°C for 20 min,the intestine showed signs of improvement and it was decided to avoid resection and instead temporary close the abdomen with vacuum-pack technique.At the second-look laparotomy 48 h later,the intestine appeared normal.The patient was discharged on the 8 th post-op day in excellent condition.CONCLUSION In case of SBO caused by adhesions,extreme caution is needed if In Is is present,as the clinical signs are mild and you should rely for diagnosis in CT findings and lactate levels.Conservative surgical approach could reverse the effects of In Is,if performed quickly,so that intestinal resection is avoided and should be used even when minimum signs of viability are present. 展开更多
关键词 INTRAABDOMINAL ADHESIONS Intestinal ISCHEMIA Small BOWEL OBSTRUCTION Vacuum-pack technique case report Conservative surgical approach
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经腋窝后缘入路与肩胛骨外侧缘入路治疗肩胛骨骨折的对照研究 被引量:1
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作者 李冰 徐鹏 +2 位作者 袁亚兵 张兴州 何樟宁 《中国骨伤》 2025年第3期231-237,共7页
目的:比较经腋窝后缘入路与经肩胛骨外侧缘入路治疗MillerⅡ、Ⅳ型肩胛骨骨折的临床疗效。方法:回顾性分析自2020年6月至2024年6月采用切开复位锁定钢板内固定治疗的28例新鲜肩胛骨骨折(MillerⅡ、Ⅳ型)患者,按手术入路方式不同分为两... 目的:比较经腋窝后缘入路与经肩胛骨外侧缘入路治疗MillerⅡ、Ⅳ型肩胛骨骨折的临床疗效。方法:回顾性分析自2020年6月至2024年6月采用切开复位锁定钢板内固定治疗的28例新鲜肩胛骨骨折(MillerⅡ、Ⅳ型)患者,按手术入路方式不同分为两组。腋窝后缘组13例,男8例,女5例;年龄26~71(39.2±6.5)岁;Miller分型,Ⅱ型5例,Ⅳ型8例;摔伤9例,车祸伤4例;右侧7例,左侧6例;受伤至手术时间3~5(4.07±0.86)d。肩胛骨外侧缘组15例,男10例,女5例;年龄27~63(43.6±8.5)岁;Miller分型,Ⅱ型7例,Ⅳ型8例;摔伤10例,车祸伤5例;右侧6例,左侧9例;受伤至手术时间3~5(4.20±0.67)d。比较两组手术时间、术中失血量、骨折愈合时间、术后即刻盂极角(glenopolar angle,GPA)等情况。分别于术后3、6个月时采用疼痛视觉模拟评分(visual analogue scale,VAS)、Constant-Murley肩关节功能评分进行临床疗效评价,并于术后6个月评价关节活动度情况。结果:所有患者未出现伤口感染、血管和神经损伤、内固定松动或断裂。两组均获得随访,时间8~12(9.6±1.5)个月。腋窝后缘组手术时间、术中失血量分别为(76.92±5.60)min、(84.86±10.08)ml,优于肩胛骨外侧缘组(84.67±6.93)min、(115.00±12.39)ml,差异有统计学意义(P<0.05)。腋窝后缘组、肩胛骨外侧缘组术后即刻GPA[(36.62±0.87)°、(36.20±0.82)°]较术前[(16.10±1.14)°、(16.20±1.20)°]显著改善,差异有统计学意义(P<0.05),但两组间比较差异无统计学意义(P>0.05)。两组骨折愈合时间及术后3、6个月VAS比较,差异均无统计学意义(P>0.05)。术后3个月腋窝后缘组Constant-Murley评分(75.00±4.02)分高于肩胛骨外侧缘组(70.86±4.24)分,差异有统计学意义(P<0.05),术后6个月两组比较差异无统计学意义(P>0.05)。术后6个月,腋窝后缘组关节活动度前屈(160.38±13.61)°、外展(154.61±13.91)°、外旋(83.08±2.53)°、内旋(62.69±2.59)°、后伸(51.54±3.15)°,大于肩胛骨外侧缘组(148.00±15.44)°、(144.00±11.05)°、(79.67±3.99)°、(57.33±4.95)°、(47.33±4.16)°,差异有统计学意义(P<0.05)。结论:与肩胛骨外侧缘肌间隙入路相比,经腋窝后缘入路Buttress固定治疗MillerⅡ、Ⅳ型肩胛骨骨折,术中视野暴露广泛,骨折支撑固定稳固,手术创伤小,手术时间短,术中出血量少,为治疗复杂肩胛骨骨折提供新的借鉴。 展开更多
关键词 肩胛骨骨折 腋窝后缘入路 肩胛骨外侧缘入路 病例对照研究
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基于案例式、启发式、探究式的设计素描教学方法与实践
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作者 薛生健 郭丹 《湖北开放职业学院学报》 2025年第9期172-175,共4页
人工智能时代的设计教育需求背景下,设计素描课程的教学观念、教学形式与教学体系都发生了相应的变化。基于此,案例式、启发式、探究式教学模式,旨在构建一个能够全面提升学生设计思维与实际操作能力的课程训练体系。强调通过自主探究... 人工智能时代的设计教育需求背景下,设计素描课程的教学观念、教学形式与教学体系都发生了相应的变化。基于此,案例式、启发式、探究式教学模式,旨在构建一个能够全面提升学生设计思维与实际操作能力的课程训练体系。强调通过自主探究、发现规律的过程,强调的是体验,而不是模仿,强调的不是模式,而是思路,重视的不是结果,而是过程。以此强化设计素描课程训练中的“设计性”“创造性”,实现从“教师中心”向“学生中心”的转变,促进设计素描课程教学质量与效果的全面提升。 展开更多
关键词 案例式 启发式 探究式 设计素描 教学方法
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司法精神病重复鉴定8例及原因分析
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作者 范华 朱明霞 +1 位作者 杨会 陈顺驰 《中国法医学杂志》 2025年第2期237-240,共4页
重复鉴定一直是司法界的难题,某些重大、复杂、疑难等刑事案件,因鉴定意见存在异议,为确保鉴定意见的公正性和客观性,办案机关往往仍需提请重新鉴定。本文结合案例,对多次鉴定案件的鉴定思路,提出若干分析意见,供同行参考讨论。
关键词 三次及以上鉴定 刑事案件 鉴定思路
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中国海洋文化遗产调查路径与实践新探
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作者 马树华 滕浩然 任环宇 《文化软实力研究》 2025年第1期5-13,共9页
调查研究是海洋文化遗产保护和传承的基础,也是目前较为薄弱的领域。既有的文化遗产调查大多以价值导向、行业导向、名录导向和消费导向展开,取得了显著成效。海洋文化遗产是具有独特风格的遗产形态,这些既有方法不能完全适用于其历史... 调查研究是海洋文化遗产保护和传承的基础,也是目前较为薄弱的领域。既有的文化遗产调查大多以价值导向、行业导向、名录导向和消费导向展开,取得了显著成效。海洋文化遗产是具有独特风格的遗产形态,这些既有方法不能完全适用于其历史文化价值的挖掘。因此,不拘泥于单一导向,从元问题出发,遵循“审慎舍弃”原则,围绕“三板块”和“六要素”展开调查研究,回到海洋文化遗产生成的现场与本源,发掘海洋文化遗产各要素之间的关系,可以为探索海洋文化遗产的挖掘、保护与活化利用提供国家战略、文化体制改革以及学术创新等层面的参考。 展开更多
关键词 海洋文化遗产 元问题 调查路径 案例
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以需求为导向的动态全程个案管理在膀胱癌输尿管皮肤造口患者中的应用
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作者 刘洁 王雪静 +2 位作者 严艳红 姜巧玲 周珊 《河北医药》 2025年第11期1855-1858,共4页
目的评价以需求为导向的动态全程个案管理在膀胱癌输尿管皮肤造口患者中的应用效果。方法选取2023年1月至2024年2月南京医科大学第一附属医院收治的膀胱癌输尿管皮肤造口患者96例为研究对象,随机分2组,每组48例。对照组采取常规干预,观... 目的评价以需求为导向的动态全程个案管理在膀胱癌输尿管皮肤造口患者中的应用效果。方法选取2023年1月至2024年2月南京医科大学第一附属医院收治的膀胱癌输尿管皮肤造口患者96例为研究对象,随机分2组,每组48例。对照组采取常规干预,观察组实施以需求为导向的动态全程个案管理,比较2组的病耻感、自护能力和自护知识评分、术后造口相关并发症和周围感染发生情况、生活质量评分、护理满意度评分。结果社会影响量表(SIS)各维度评分观察组和对照组比较,2组干预后均低于干预前,且观察组SIS各维度评分低于对照组(P<0.05)。自护能力和自护知识评分观察组和对照组比较,2组干预后均高于干预前,观察组高于对照组(P<0.05)。观察组和对照组的术后造口相关并发症发生率分别为2.08%和16.67%,造口周围感染发生率分别为4.17%和20.83%,观察组低于对照组(P<0.05)。生活质量评分比较,与干预前比较,2组干预后均升高,观察组较对照组更高(P<0.05)。观察组满意度评分高于对照组(P<0.05)。结论膀胱癌输尿管皮肤造口患者实施以需求为导向的动态全程个案管理,可增强患者自护知识,减轻患者病耻感,减少术后造口周围感染率和相关并发症,能有效促进患者生活质量和自护能力得到提升,患者的护理满意度高。 展开更多
关键词 输尿管 膀胱癌 以需求为导向 皮肤造口 个案管理
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CBL联合Peyton四步教学法在住培生血常规轮转培训中的应用与成效评估
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作者 于连辉 黄媛 +1 位作者 王庚 秦绪珍 《标记免疫分析与临床》 2025年第11期2386-2390,共5页
目的探讨案例教学法(CBL)联合Peyton四步教学法在检验科住院医师(住培生)血常规轮转培训中的应用效果,并评估其在提升住培生血常规审核、散点图识别及临床思维能力方面的成效。方法选取2024年2月至2025年6月于北京协和医院检验科血常规... 目的探讨案例教学法(CBL)联合Peyton四步教学法在检验科住院医师(住培生)血常规轮转培训中的应用效果,并评估其在提升住培生血常规审核、散点图识别及临床思维能力方面的成效。方法选取2024年2月至2025年6月于北京协和医院检验科血常规岗轮转的15名住培生为研究对象。运用CBL与Peyton四步教学法相结合的新教学模式,并采用报告单初审+即时指正和出组前病例汇报等特色教学环节,根据住培生初审血常规报告的错误率及出组前病例汇报情况,量化评估教学效果。结果住培生共完成3206例血常规报告初审,总错误率为6.39%。平均错误率培训初期为6.04%,培训末期为3.33%(P<0.01)。12名住培生(80%)的住培生错误率有所下降,9名住培生(60%)在轮转结束时实现零错误审核。病例汇报中,50%的住培生汇报内容涉及血常规及其散点图解读,锻炼临床思维与检验技能相结合。结论CBL联合Peyton四步教学法,结合特色“初审”和“病例汇报”模式,能有效提升住培生血常规报告的审核准确性和临床思维能力,对培养高素质检验人才、保障医疗质量具有积极的推动作用,具有推广价值。 展开更多
关键词 案例教学法 Peyton四步教学法 住院医师培训 血常规轮转培训 教学效果评估
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1例具有肾病家族史疑似Alport综合征的诊疗思路探讨
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作者 杨雯尹 倪杰 +2 位作者 许陵冬 孙伟 赵静 《四川中医》 2025年第11期146-154,共9页
回顾性分析1例慢性肾脏病4期,但其临床表现疑似Alport综合征(AS)的病案,其具有特征性慢性肾脏病家族史临床资料。临床表现为肾功能下降、耳鸣,神经性耳聋,但未见明显血尿或蛋白尿。值得注意的是,该患者具有感音神经性耳聋家族史,其肾病... 回顾性分析1例慢性肾脏病4期,但其临床表现疑似Alport综合征(AS)的病案,其具有特征性慢性肾脏病家族史临床资料。临床表现为肾功能下降、耳鸣,神经性耳聋,但未见明显血尿或蛋白尿。值得注意的是,该患者具有感音神经性耳聋家族史,其肾病家族系谱提示可疑常染色体隐性遗传。经过中西医结合治疗后,肾功能相关指标较前好转。因此,本文基于详细的病史采集、综合分析及鉴别诊断,对该病例展开探讨。该案例凸显了在精准医学时代,传统的临床资料采集、详细的家族史追溯和严密的逻辑推理,在面对罕见病诊断困境时,依然是不可或缺的关键环节。同时,本文也初步探讨益肾泄浊法延缓AS引起的慢性肾衰竭的可能性,以期为中医治疗AS提供新思路。 展开更多
关键词 ALPORT综合征 家族性肾病 病例报告 诊疗思路
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《医学心悟》辨治便秘思路探究及临证举隅
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作者 汪承芳 夏勇 +3 位作者 董昌武 尹刚 汪丽姣 黄孝周 《基层中医药》 2025年第6期32-36,共5页
通过对程国彭临床经典著作《医学心悟》的研读,发现程氏对便秘的辨治思路和特点鲜明:首先,审证求因,归纳出“实闭”为阳明胃实,腑气不通;“虚闭”为精亏血少,肠枯不润;“热闭”为邪热内盛,肠滞不下;“冷闭”为中虚脏寒,肠凝不运等四大... 通过对程国彭临床经典著作《医学心悟》的研读,发现程氏对便秘的辨治思路和特点鲜明:首先,审证求因,归纳出“实闭”为阳明胃实,腑气不通;“虚闭”为精亏血少,肠枯不润;“热闭”为邪热内盛,肠滞不下;“冷闭”为中虚脏寒,肠凝不运等四大病因病机。其次,因证施治,分别治以泻下除满,荡涤通腑;补血益精,润肠通便;清热消积,泻下除滞;温中散寒,健脾运肠。最后,还需量虚实用,视病性之虚实、病情之轻重及素体之羸硕,酌情攻下,中病即止,切勿滥用。笔者将其辨治思路应用于临床,体会一二,现略作阐述,以期对临床有所启悟。 展开更多
关键词 医学心悟 便秘 辨治思路 临证举隅
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融合多维空间相似理论与机器学习算法的山区铁路桥梁智能选型方法 被引量:2
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作者 李媛 韩峰 +1 位作者 白如博 魏昊 《铁道标准设计》 北大核心 2025年第4期93-101,共9页
为充分挖掘既有桥梁案例知识与专家经验,模拟专业工程师进行桥梁选型,提高桥梁选型水平和效率,提出融合多维空间相似理论与机器学习算法的山区铁路桥梁智能选型研究方法。综合考虑工程资料、地形地质、水文气象3个层面,选取11个特征属... 为充分挖掘既有桥梁案例知识与专家经验,模拟专业工程师进行桥梁选型,提高桥梁选型水平和效率,提出融合多维空间相似理论与机器学习算法的山区铁路桥梁智能选型研究方法。综合考虑工程资料、地形地质、水文气象3个层面,选取11个特征属性构建山区铁路桥梁选型的层次指标体系,并利用组合赋权法确定各指标权重。以历史桥梁案例资料为基础,按照一定的入库规则与案例表征方法进行案例表征。应用GIS划分既有案例的属性单元并设计入库规则,融合多维空间相似理论建立山区铁路桥梁GIS案例库,计算目标案例与既有案例的相似度,设计案例的相似性判别准则,进行案例的检索与推荐应用。将最近邻检索策略引入案例检索过程中,以检索得到的既有案例为样本数据集,设计BP神经网络模型模拟人脑训练和学习,进行铁路桥型智能选择研究。同时采用决策树、K近邻与支持向量机3种回归预测方法进行铁路桥梁的智能选型,选型结果与BP神经网络算法的预测准确度进行对比。以某山区铁路大桥为工程实例,进行方法验证。研究结果表明:模型选型结果与实际桥型一致,方法可用于西部艰险山区铁路桥梁选型,同时为智能化选线设计提供了新思路。 展开更多
关键词 多维空间相似理论 机器学习算法 桥梁智能选型 GIS案例库 相似性判别准则 组合赋权法
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案例驱动《化工过程设计及节能技术》课堂教学——合成氨工艺节能减碳
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作者 颜婷珪 徐梅松 陈政 《广东化工》 2025年第14期165-167,145,共4页
在新工科背景下,为提升学生解决实际工程问题的能力,教学改革选取了合成氨工艺的节能减碳案例,围绕该案例设计了基础、综合、实践、创新等不同层级的问题体系,融入《化工过程设计及节能技术》课程,针对煤气化、变换反应、合成氨反应的... 在新工科背景下,为提升学生解决实际工程问题的能力,教学改革选取了合成氨工艺的节能减碳案例,围绕该案例设计了基础、综合、实践、创新等不同层级的问题体系,融入《化工过程设计及节能技术》课程,针对煤气化、变换反应、合成氨反应的设计及分析和全过程系统的换热网络设计及能量优化环节建立了围绕各工段的设计任务,通过多层次目标问题完善了多元化考核评价机制,验证案例教学在提升学生学习效果中的有效性。 展开更多
关键词 问题导向 实践能力 案例教学 节能降碳
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城市更新多元协同治理的实践路径与内在机制——基于杭州的探索性案例研究 被引量:5
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作者 徐可西 苏婕妤 鲍海君 《自然资源学报》 北大核心 2025年第6期1451-1467,共17页
创新多元协同治理模式是应对中国城市更新价值转变与破解发展困局的重要抓手,是推动城市高质量发展的迫切需要。从治理要素的整体协同视角出发,运用案例研究和归纳分析法,以杭州为典型案例,系统解析城市更新协同治理的实践路径与内在机... 创新多元协同治理模式是应对中国城市更新价值转变与破解发展困局的重要抓手,是推动城市高质量发展的迫切需要。从治理要素的整体协同视角出发,运用案例研究和归纳分析法,以杭州为典型案例,系统解析城市更新协同治理的实践路径与内在机制。结果表明:(1)杭州城市更新形成了统筹管理体制与多元政策工具的治理环境建设、“政府、市场、居民、社会”四心协同的治理结构搭建、“知识—话语”与“实体技术”协同的治理手段应用、“发展、民生、保护”多目标协同的治理结果达成等四条多元协同治理路径。(2)城市更新多元协同治理应是涵盖“协同环境—协同结构—协同手段—协同结果”的整体协同,通过自洽型统筹管理与协调型政策创新的环境协同机制、多元化利益协调与差异化权力配置的结构协同机制、规范性程序驱动与激励性刚弹管控的手段协同机制、冲突性目标共生与差异性全民共享的结果协同机制,实现城市更新高质量发展目标。基于此,提出以责权协调与动态调适为原则,协同创新统筹型管理体制与政策工具;根据角色定位差异化配置主体权力,形成兼容型城市更新治理共同体;以规范与激励为基点,创新刚弹结合的城市更新治理手段;兼顾效率与公平,促进经济、社会、环境等多维目标协调发展等治理启示,为新发展阶段下的城市更新治理提供经验借鉴。 展开更多
关键词 城市更新 实践路径 内在机制 多元协同治理 案例研究 杭州
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PBL联合CBL教学法用于骨关节外科住院医师规范化培训教学的效果
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作者 李俊杰 李坤 高帅 《中国卫生产业》 2025年第15期150-153,共4页
目的探究在骨关节外科住院医师规范化培训(简称住培)中应用问题教学法(problem-based learning,PBL)结合案例教学法(case-based learning,CBL)的效果。方法选取2022年6月—2024年3月山东第二医科大学附属医院骨关节外科的25名住培医师,... 目的探究在骨关节外科住院医师规范化培训(简称住培)中应用问题教学法(problem-based learning,PBL)结合案例教学法(case-based learning,CBL)的效果。方法选取2022年6月—2024年3月山东第二医科大学附属医院骨关节外科的25名住培医师,依据随机数字表法分为两组。对照组(12名)采用传统教学法;观察组(13名)采用PBL结合CBL教学法。对比两组考核成绩、自我导向学习能力、教学满意度。结果观察组的理论知识、临床技能、综合能力分别为(94.22±2.48)分、(94.24±3.70)分、(93.61±2.12)分,均高于对照组的(91.13±3.54)分、(88.50±3.86)分、(90.98±3.08)分,差异均有统计学意义(t=2.545,3.796,2.504;P均<0.05)。观察组教学后的自我导向学习能力和教学满意度高于对照组,差异均有统计学意义(P均<0.05)。结论在骨关节外科住院医师规范化培训教学时采用PBL与CBL联合教学法,可提高住培医师的考核成绩,增强自我导向学习能力,对教学更加满意。 展开更多
关键词 问题教学法 案例教学法 骨关节外科 住院医师规范化培训 考核成绩
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谈药剂学教学案例的设计——以“基于氢为治疗物质的药物制剂及其设计”为例
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作者 郝吉福 何玉静 +2 位作者 毕研平 王建筑 刘腾 《药学教育》 2025年第4期116-119,共4页
案例教学作为药学专业学位研究生教育中重要的教学方法,能够有效地推动药学高层次人才培养模式的落实。而教学案例的设计是开展案例教学的基础。本文以授权的发明专利“基于氢为治疗物质的药物制剂及其设计”为例,阐述药剂学教学案例建... 案例教学作为药学专业学位研究生教育中重要的教学方法,能够有效地推动药学高层次人才培养模式的落实。而教学案例的设计是开展案例教学的基础。本文以授权的发明专利“基于氢为治疗物质的药物制剂及其设计”为例,阐述药剂学教学案例建设的必要性与可行性,以及如何合理地设计药剂学教学案例。以期通过教学案例的构建将优质的科研资源转化为教学资源,达到培养应用型研究人才的目的。 展开更多
关键词 药学专业学位 药剂学 教学案例 教学方法
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