The paper develops a methodology for the optimal sizing of a generic wind farms, focusing primarily on reliability aspects, besides the traditional economic ones. A specific objective function is proposed in order to ...The paper develops a methodology for the optimal sizing of a generic wind farms, focusing primarily on reliability aspects, besides the traditional economic ones. A specific objective function is proposed in order to select the better wind farm configuration, based upon the profits related to the economic trading in the deregulated electric market and the costs due to investment, operation & management, and to system unavailability. This objective function is accurately investigated as a function of the turbines number in order to derive the most convenient alternative, which implies also the optimal choice of the single wind generators size. The ranking coming out from this assessment is then compared with that one established in terms of expected load not supplied. A compromise choice, between the best alternatives provided by the two criteria has finally adopted. A simple numerical application is reported in the last part of the paper for testing the validity of the proposed approach. Also uncertainty aspects in the basic input parameters are taken into account and possible way of dealing with them is briefly illustrated.展开更多
The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medici...The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medicinal product and re-evaluation of generic medicinal product.In China,RLDs are sourced from various origins,but their quality and market availability can be constrained by multiple factors,including emergent issues such as nitrosamine impurities.Five classes of medicinal products have been reported to be at risk for containing nitrosamine impurities:sartan-based medicines,metformin-containing products,ranitidine medicines,rifampicin medicines,and Champix.This paper explores the control strategies implemented by drug regulatory agencies in the United States and the European Union to manage nitrosamine impurities and assesses their impact on the market availability and quality of RLDs in China.The aim is to offer valuable insights for generic drug manufacturers and regulatory bodies both domestically and internationally.展开更多
Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a...Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a decrease in the volume of pediatric heart transplantation to the lowest volume in a decade.Organ availability remains a major limiting factor affecting transplant volume.This mandates that innovation must take place to increase the supply of donor organs.While some strategies such as donation after cardiac death,hepatitis C virus+transplantation,and ABO-incompatible transplantation have increased the pool for donation,it still falls short of meeting the demand.Other proposed strategies include splitting the donor heart to provide multiple partial heart transplants,domino partial heart transplantation,changes in legislation including opt-out legislation,and xenotransplantation.Further evolution and refinement of these strategies will make a meaningful impact on patients awaiting life-saving heart transplants.展开更多
Recent work analysing magnesium hydrogenation using Reflecting Electron Energy Loss Spectroscopy(REELS)and Density Function Theory(DFT)has indicated interfacial polarisation and interstitial hydrogen clustering influe...Recent work analysing magnesium hydrogenation using Reflecting Electron Energy Loss Spectroscopy(REELS)and Density Function Theory(DFT)has indicated interfacial polarisation and interstitial hydrogen clustering influence the reaction rate.The site availability model has been modified to include interstitial hydrogen clustering within the site availability factor and interface polarisation using interface treatment.The new model,SAM-CV-S,has demonstrated improved modelling of magnesium hydrogenation across wide operating conditions,such as temperatures from 330 to 400℃and pressures up to 40 bar.This wide applicability makes it a robust model that can be used to simulate bed performance in solid-state hydrogen stores.Thus,the site availability factor successfully combines interstitial hydrogen clustering with thermal resistance effects,which are known to strongly influence metal hydride reactor designs at scale.The next phase of the model is to incorporate a predictive hydrogen capacity method into the model.展开更多
Precipitation projections over the Tibetan Plateau(TP)show diversity among existing studies,partly due to model uncertainty.How to develop a reliable projection remains inconclusive.Here,based on the IPCC AR6–assesse...Precipitation projections over the Tibetan Plateau(TP)show diversity among existing studies,partly due to model uncertainty.How to develop a reliable projection remains inconclusive.Here,based on the IPCC AR6–assessed likely range of equilibrium climate sensitivity(ECS)and the climatological precipitation performance,the authors constrain the CMIP6(phase 6 of the Coupled Model Intercomparison Project)model projection of summer precipitation and water availability over the TP.The best estimates of precipitation changes are 0.24,0.25,and 0.45 mm d^(−1)(5.9%,6.1%,and 11.2%)under the Shared Socioeconomic Pathway(SSP)scenarios of SSP1–2.6,SSP2–4.5,and SSP5–8.5 from 2050–2099 relative to 1965–2014,respectively.The corresponding constrained projections of water availability measured by precipitation minus evaporation(P–E)are 0.10,0.09,and 0.22 mm d^(−1)(5.7%,4.9%,and 13.2%),respectively.The increase of precipitation and P–E projected by the high-ECS models,whose ECS values are higher than the upper limit of the likely range,are about 1.7 times larger than those estimated by constrained projections.Spatially,there is a larger increase in precipitation and P–E over the eastern TP,while the western part shows a relatively weak difference in precipitation and a drier trend in P–E.The wetter TP projected by the high-ECS models resulted from both an approximately 1.2–1.4 times stronger hydrological sensitivity and additional warming of 0.6℃–1.2℃under all three scenarios during 2050–2099.This study emphasizes that selecting climate models with climate sensitivity within the likely range is crucial to reducing the uncertainty in the projection of TP precipitation and water availability changes.展开更多
Applying organic waste and inorganic additives during composting can be an effective and easy-to-control strategy for optimizing humification,maturation,and the availability of essential mineral elements in compost.In...Applying organic waste and inorganic additives during composting can be an effective and easy-to-control strategy for optimizing humification,maturation,and the availability of essential mineral elements in compost.In this respect,this study aims to evaluate the effect of organic(olive-mill waste and horse manure)and inorganic(phosphogypsum)additives on the evolution of maturity indices,aromatic compounds,and nutrient availability during composting.Four mixtures[horse manure+green waste(M1),olive-mill+green waste(M2),sewage-sludge+phos-phogypsum+green waste(M3),and green waste(M4)]were carried out.Physicochemical(temperature,pH,phosphorus,nitrogen,and carbon-to-nitrogen(C/N)ratio),infrared-spectroscopic,and phytotoxicity were monitored.The results showed that(in)organic additives have a positive effect on maturity and humification indices,pH stability,and the phosphorus and nitrogen availability in the composts produced.The horse manure additive reduced the carbon and increased the nitrogen,reducing the C/N ratio.Phosphogypsum and olive-mill reduced phytotoxicity,boosting the nitrogen and phosphorus availability of in composts.Fourier transform infrared spectroscopy(FT-IR)analysis revealed that phosphogypsum and olive-mill addition improved the aromatic compounds and reduced the aliphatic ones in M3 and M4 com-posts.These results suggest new approaches to promoting maturity and stability,as well as phosphorus and nitrogen availability in composts,through better use of organic waste and inorganic additives in composting.展开更多
As an apex predator in arid steppe,saker falcon plays a crucial role in maintaining ecosystem balance.Understanding their movement patterns concerning conspecific competition and prey availability is important for the...As an apex predator in arid steppe,saker falcon plays a crucial role in maintaining ecosystem balance.Understanding their movement patterns concerning conspecific competition and prey availability is important for their conservation.We aim to understand how movement pattern of breeding saker falcons relates to prey availability.Twelve adult sakers were tracked during the breeding seasons,using satellite transmitters.Throughout the breeding season,sakers exhibited territorial behavior,with minimal overlap in range use among neighboring conspecifics.Males occupied larger areas(mean=2,397 ha,median=1,221 ha),compared to females(mean=1,241 ha,median=554 ha),and it remained consistent throughout breeding season.Female home range size increased notably during a late nestling stage and post-fledging dependence periods,indicating release from brooding constraints.Notably,we found a negative relationship between male home range size and prey availability.In high rodent density areas,males occupied smaller areas(mean=1,135 ha,median=1,034 ha),contrasting with low rodent density areas(mean=6,815 ha,median=6,516 ha).However,no significant relationship was observed between female home range size and prey availability.We also noted instances of nest abandonment and early dispersal behavior in some females,potentially influenced by a handicapping effect of tagging.Our findings offer valuable insight into how prey availability shapes saker falcon space use and defines their spatial requirements for successful breeding.This knowledge is crucial for the conservation and management of globally endangered saker falcons,informing targeted habitat protection and resource management strategies.展开更多
Currently,distributed routing protocols are constrained by offering a single path between any pair of nodes,thereby limiting the potential throughput and overall network performance.This approach not only restricts th...Currently,distributed routing protocols are constrained by offering a single path between any pair of nodes,thereby limiting the potential throughput and overall network performance.This approach not only restricts the flow of data but also makes the network susceptible to failures in case the primary path is disrupted.In contrast,routing protocols that leverage multiple paths within the network offer a more resilient and efficient solution.Multipath routing,as a fundamental concept,surpasses the limitations of traditional shortest path first protocols.It not only redirects traffic to unused resources,effectively mitigating network congestion,but also ensures load balancing across the network.This optimization significantly improves network utilization and boosts the overall performance,making it a widely recognized efficient method for enhancing network reliability.To further strengthen network resilience against failures,we introduce a routing scheme known as Multiple Nodes with at least Two Choices(MNTC).This innovative approach aims to significantly enhance network availability by providing each node with at least two routing choices.By doing so,it not only reduces the dependency on a single path but also creates redundant paths that can be utilized in case of failures,thereby enhancing the overall resilience of the network.To ensure the optimal placement of nodes,we propose three incremental deployment algorithms.These algorithms carefully select the most suitable set of nodes for deployment,taking into account various factors such as node connectivity,traffic patterns,and network topology.By deployingMNTCon a carefully chosen set of nodes,we can significantly enhance network reliability without the need for a complete overhaul of the existing infrastructure.We have conducted extensive evaluations of MNTC in diverse topological spaces,demonstrating its effectiveness in maintaining high network availability with minimal path stretch.The results are impressive,showing that even when implemented on just 60%of nodes,our incremental deployment method significantly boosts network availability.This underscores the potential of MNTC in enhancing network resilience and performance,making it a viable solution for modern networks facing increasing demands and complexities.The algorithms OSPF,TBFH,DC and LFC perform fast rerouting based on strict conditions,while MNTC is not restricted by these conditions.In five real network topologies,the average network availability ofMNTCis improved by 14.68%,6.28%,4.76%and 2.84%,respectively,compared with OSPF,TBFH,DC and LFC.展开更多
Toilet facilities in public places are a necessity and are supposed to be present in any public place where people visit. Despite the importance of toilet facilities in public places, there is limited access to toilet...Toilet facilities in public places are a necessity and are supposed to be present in any public place where people visit. Despite the importance of toilet facilities in public places, there is limited access to toilet facilities in public places in Sub-Saharan Africa and this has been a persistent issue. Given that limited studies have been done on availability and use of toilets in public places, this study aimed to fill this research gap. To achieve the objective of the study, a cross-sectional study was used to select participants from the study site. The sample size was 400 after adjustment for non-response. Results from the study showed promising as 95% of public places had a toilet and water for hand washing. However, most of the toilet facilities lacked soap. Toilets in offices and hospitals were perceived to be cleaner and of good quality compared to those in markets and travel agencies. Results also showed that participants hardly used toilets in markets and travel agencies. Toilet facilities in offices and churches were most used, as office toilets were rated clean and of good quality by the participants. The study recommends the need for routine checks by the council to ensure the presence of toilet facilities in public places and the need to sensitise business owners on the importance of having and maintaining toilet facilities in their business establishments.展开更多
Cloud computing allows scalability at a lower cost for data analytics in a big data environment. This paradigm considers the dimensioning of resources to process different volumes of data, minimizing the response time...Cloud computing allows scalability at a lower cost for data analytics in a big data environment. This paradigm considers the dimensioning of resources to process different volumes of data, minimizing the response time of big data. This work proposes a performance and availability evaluation of big data environments in the private cloud through a methodology and stochastic and combinatorial models considering performance metrics such as execution times, processor utilization, memory utilization, and availability. The proposed methodology considers objective activities, performance, and availability modeling to evaluate the private cloud environment. A performance model based on stochastic Petrinets is adopted to evaluate the big data environment on the private cloud. Reliability block diagram models are adopted to evaluate the availability of big environment data in the private cloud. Two case studies based on the CloudStack platform and Hadoop cluster are adopted to demonstrate the viability of the proposed methodologies and models. Case Study 1 evaluated the performance metrics of the Hadoop cluster in the private cloud, considering different service offerings, workloads, and the number of data sets. The sentiment analysis technique is used in tweets from users with symptoms of depression to generate the analyzed datasets. Case Study 2 evaluated the availability of big data environments in the private cloud.展开更多
文摘The paper develops a methodology for the optimal sizing of a generic wind farms, focusing primarily on reliability aspects, besides the traditional economic ones. A specific objective function is proposed in order to select the better wind farm configuration, based upon the profits related to the economic trading in the deregulated electric market and the costs due to investment, operation & management, and to system unavailability. This objective function is accurately investigated as a function of the turbines number in order to derive the most convenient alternative, which implies also the optimal choice of the single wind generators size. The ranking coming out from this assessment is then compared with that one established in terms of expected load not supplied. A compromise choice, between the best alternatives provided by the two criteria has finally adopted. A simple numerical application is reported in the last part of the paper for testing the validity of the proposed approach. Also uncertainty aspects in the basic input parameters are taken into account and possible way of dealing with them is briefly illustrated.
基金Subject construction funding project of Institute for Chemical Drug Control(Grant No.2024HYZX42)in National Institutes for Food and Drug Control,Beijing,China。
文摘The Reference Listed drug(RLD)plays a critical role in the development and research of generic medicinal products,serving as the comparator product used in the marketing authorization application of new generic medicinal product and re-evaluation of generic medicinal product.In China,RLDs are sourced from various origins,but their quality and market availability can be constrained by multiple factors,including emergent issues such as nitrosamine impurities.Five classes of medicinal products have been reported to be at risk for containing nitrosamine impurities:sartan-based medicines,metformin-containing products,ranitidine medicines,rifampicin medicines,and Champix.This paper explores the control strategies implemented by drug regulatory agencies in the United States and the European Union to manage nitrosamine impurities and assesses their impact on the market availability and quality of RLDs in China.The aim is to offer valuable insights for generic drug manufacturers and regulatory bodies both domestically and internationally.
文摘Heart transplantation is a life-saving procedure for many people throughout the world.Data shows that in 2024,there was an increase in the volume of adult heart transplantation in the United States even as there was a decrease in the volume of pediatric heart transplantation to the lowest volume in a decade.Organ availability remains a major limiting factor affecting transplant volume.This mandates that innovation must take place to increase the supply of donor organs.While some strategies such as donation after cardiac death,hepatitis C virus+transplantation,and ABO-incompatible transplantation have increased the pool for donation,it still falls short of meeting the demand.Other proposed strategies include splitting the donor heart to provide multiple partial heart transplants,domino partial heart transplantation,changes in legislation including opt-out legislation,and xenotransplantation.Further evolution and refinement of these strategies will make a meaningful impact on patients awaiting life-saving heart transplants.
基金funded through Engineering and Physical Sciences Research Council(EPSRC)[grant numbers EP/W005131/1,EP/V042556/1].
文摘Recent work analysing magnesium hydrogenation using Reflecting Electron Energy Loss Spectroscopy(REELS)and Density Function Theory(DFT)has indicated interfacial polarisation and interstitial hydrogen clustering influence the reaction rate.The site availability model has been modified to include interstitial hydrogen clustering within the site availability factor and interface polarisation using interface treatment.The new model,SAM-CV-S,has demonstrated improved modelling of magnesium hydrogenation across wide operating conditions,such as temperatures from 330 to 400℃and pressures up to 40 bar.This wide applicability makes it a robust model that can be used to simulate bed performance in solid-state hydrogen stores.Thus,the site availability factor successfully combines interstitial hydrogen clustering with thermal resistance effects,which are known to strongly influence metal hydride reactor designs at scale.The next phase of the model is to incorporate a predictive hydrogen capacity method into the model.
基金supported by the Second Tibetan Plateau Scientific Expedition and Research(STEP)program[grant number 2019QZKK0102]the Chinese Academy of Sciences[grant number 060GJHZ2023079GC].
文摘Precipitation projections over the Tibetan Plateau(TP)show diversity among existing studies,partly due to model uncertainty.How to develop a reliable projection remains inconclusive.Here,based on the IPCC AR6–assessed likely range of equilibrium climate sensitivity(ECS)and the climatological precipitation performance,the authors constrain the CMIP6(phase 6 of the Coupled Model Intercomparison Project)model projection of summer precipitation and water availability over the TP.The best estimates of precipitation changes are 0.24,0.25,and 0.45 mm d^(−1)(5.9%,6.1%,and 11.2%)under the Shared Socioeconomic Pathway(SSP)scenarios of SSP1–2.6,SSP2–4.5,and SSP5–8.5 from 2050–2099 relative to 1965–2014,respectively.The corresponding constrained projections of water availability measured by precipitation minus evaporation(P–E)are 0.10,0.09,and 0.22 mm d^(−1)(5.7%,4.9%,and 13.2%),respectively.The increase of precipitation and P–E projected by the high-ECS models,whose ECS values are higher than the upper limit of the likely range,are about 1.7 times larger than those estimated by constrained projections.Spatially,there is a larger increase in precipitation and P–E over the eastern TP,while the western part shows a relatively weak difference in precipitation and a drier trend in P–E.The wetter TP projected by the high-ECS models resulted from both an approximately 1.2–1.4 times stronger hydrological sensitivity and additional warming of 0.6℃–1.2℃under all three scenarios during 2050–2099.This study emphasizes that selecting climate models with climate sensitivity within the likely range is crucial to reducing the uncertainty in the projection of TP precipitation and water availability changes.
文摘Applying organic waste and inorganic additives during composting can be an effective and easy-to-control strategy for optimizing humification,maturation,and the availability of essential mineral elements in compost.In this respect,this study aims to evaluate the effect of organic(olive-mill waste and horse manure)and inorganic(phosphogypsum)additives on the evolution of maturity indices,aromatic compounds,and nutrient availability during composting.Four mixtures[horse manure+green waste(M1),olive-mill+green waste(M2),sewage-sludge+phos-phogypsum+green waste(M3),and green waste(M4)]were carried out.Physicochemical(temperature,pH,phosphorus,nitrogen,and carbon-to-nitrogen(C/N)ratio),infrared-spectroscopic,and phytotoxicity were monitored.The results showed that(in)organic additives have a positive effect on maturity and humification indices,pH stability,and the phosphorus and nitrogen availability in the composts produced.The horse manure additive reduced the carbon and increased the nitrogen,reducing the C/N ratio.Phosphogypsum and olive-mill reduced phytotoxicity,boosting the nitrogen and phosphorus availability of in composts.Fourier transform infrared spectroscopy(FT-IR)analysis revealed that phosphogypsum and olive-mill addition improved the aromatic compounds and reduced the aliphatic ones in M3 and M4 com-posts.These results suggest new approaches to promoting maturity and stability,as well as phosphorus and nitrogen availability in composts,through better use of organic waste and inorganic additives in composting.
基金funded by and undertaken on behalf of the Environment Agency Abu Dhabi(EAD)under a memorandum of understanding with Mongolia’s Ministry of Environment and Green Development(MEGD)supported by the National Natural Science Foundation of China(31930013,32361133559)+1 种基金the Third Xinjiang Scientifc Expedition Program(grant no.2022xjkk0801)the CASTWAS President’s Fellowship Programme(BB).
文摘As an apex predator in arid steppe,saker falcon plays a crucial role in maintaining ecosystem balance.Understanding their movement patterns concerning conspecific competition and prey availability is important for their conservation.We aim to understand how movement pattern of breeding saker falcons relates to prey availability.Twelve adult sakers were tracked during the breeding seasons,using satellite transmitters.Throughout the breeding season,sakers exhibited territorial behavior,with minimal overlap in range use among neighboring conspecifics.Males occupied larger areas(mean=2,397 ha,median=1,221 ha),compared to females(mean=1,241 ha,median=554 ha),and it remained consistent throughout breeding season.Female home range size increased notably during a late nestling stage and post-fledging dependence periods,indicating release from brooding constraints.Notably,we found a negative relationship between male home range size and prey availability.In high rodent density areas,males occupied smaller areas(mean=1,135 ha,median=1,034 ha),contrasting with low rodent density areas(mean=6,815 ha,median=6,516 ha).However,no significant relationship was observed between female home range size and prey availability.We also noted instances of nest abandonment and early dispersal behavior in some females,potentially influenced by a handicapping effect of tagging.Our findings offer valuable insight into how prey availability shapes saker falcon space use and defines their spatial requirements for successful breeding.This knowledge is crucial for the conservation and management of globally endangered saker falcons,informing targeted habitat protection and resource management strategies.
基金supported by Fundamental Research Program of Shanxi Province(No.20210302123444)the Research Project at the College Level of China Institute of Labor Relations(No.23XYJS018)+2 种基金the ICH Digitalization and Multi-Source Information Fusion Fujian Provincial University Engineering Research Center 2022 Open Fund Project(G3-KF2207)the China University Industry University Research Innovation Fund(No.2021FNA02009)the Key R&D Program(International Science and Technology Cooperation Project)of Shanxi Province China(No.201903D421003).
文摘Currently,distributed routing protocols are constrained by offering a single path between any pair of nodes,thereby limiting the potential throughput and overall network performance.This approach not only restricts the flow of data but also makes the network susceptible to failures in case the primary path is disrupted.In contrast,routing protocols that leverage multiple paths within the network offer a more resilient and efficient solution.Multipath routing,as a fundamental concept,surpasses the limitations of traditional shortest path first protocols.It not only redirects traffic to unused resources,effectively mitigating network congestion,but also ensures load balancing across the network.This optimization significantly improves network utilization and boosts the overall performance,making it a widely recognized efficient method for enhancing network reliability.To further strengthen network resilience against failures,we introduce a routing scheme known as Multiple Nodes with at least Two Choices(MNTC).This innovative approach aims to significantly enhance network availability by providing each node with at least two routing choices.By doing so,it not only reduces the dependency on a single path but also creates redundant paths that can be utilized in case of failures,thereby enhancing the overall resilience of the network.To ensure the optimal placement of nodes,we propose three incremental deployment algorithms.These algorithms carefully select the most suitable set of nodes for deployment,taking into account various factors such as node connectivity,traffic patterns,and network topology.By deployingMNTCon a carefully chosen set of nodes,we can significantly enhance network reliability without the need for a complete overhaul of the existing infrastructure.We have conducted extensive evaluations of MNTC in diverse topological spaces,demonstrating its effectiveness in maintaining high network availability with minimal path stretch.The results are impressive,showing that even when implemented on just 60%of nodes,our incremental deployment method significantly boosts network availability.This underscores the potential of MNTC in enhancing network resilience and performance,making it a viable solution for modern networks facing increasing demands and complexities.The algorithms OSPF,TBFH,DC and LFC perform fast rerouting based on strict conditions,while MNTC is not restricted by these conditions.In five real network topologies,the average network availability ofMNTCis improved by 14.68%,6.28%,4.76%and 2.84%,respectively,compared with OSPF,TBFH,DC and LFC.
文摘Toilet facilities in public places are a necessity and are supposed to be present in any public place where people visit. Despite the importance of toilet facilities in public places, there is limited access to toilet facilities in public places in Sub-Saharan Africa and this has been a persistent issue. Given that limited studies have been done on availability and use of toilets in public places, this study aimed to fill this research gap. To achieve the objective of the study, a cross-sectional study was used to select participants from the study site. The sample size was 400 after adjustment for non-response. Results from the study showed promising as 95% of public places had a toilet and water for hand washing. However, most of the toilet facilities lacked soap. Toilets in offices and hospitals were perceived to be cleaner and of good quality compared to those in markets and travel agencies. Results also showed that participants hardly used toilets in markets and travel agencies. Toilet facilities in offices and churches were most used, as office toilets were rated clean and of good quality by the participants. The study recommends the need for routine checks by the council to ensure the presence of toilet facilities in public places and the need to sensitise business owners on the importance of having and maintaining toilet facilities in their business establishments.
文摘Cloud computing allows scalability at a lower cost for data analytics in a big data environment. This paradigm considers the dimensioning of resources to process different volumes of data, minimizing the response time of big data. This work proposes a performance and availability evaluation of big data environments in the private cloud through a methodology and stochastic and combinatorial models considering performance metrics such as execution times, processor utilization, memory utilization, and availability. The proposed methodology considers objective activities, performance, and availability modeling to evaluate the private cloud environment. A performance model based on stochastic Petrinets is adopted to evaluate the big data environment on the private cloud. Reliability block diagram models are adopted to evaluate the availability of big environment data in the private cloud. Two case studies based on the CloudStack platform and Hadoop cluster are adopted to demonstrate the viability of the proposed methodologies and models. Case Study 1 evaluated the performance metrics of the Hadoop cluster in the private cloud, considering different service offerings, workloads, and the number of data sets. The sentiment analysis technique is used in tweets from users with symptoms of depression to generate the analyzed datasets. Case Study 2 evaluated the availability of big data environments in the private cloud.