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LA、ANA、ACA及β2-GPⅠ与复发性流产免疫失衡和妊娠结局的关系
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作者 宋珍珍 王倩 黄银娟 《分子诊断与治疗杂志》 2025年第9期1733-1735,1739,共4页
目的 探讨狼疮抗凝物(LA)、抗核抗体(ANA)、抗心磷脂抗体(ACA)及β2糖蛋白1抗体(β2-GPⅠ)与复发性流产(RSA)免疫失衡和妊娠结局的关系。方法 选取2021年8月至2024年8月郑州市第七人民医院收治的RSA患者102例为RSA组,同期无不良孕产史... 目的 探讨狼疮抗凝物(LA)、抗核抗体(ANA)、抗心磷脂抗体(ACA)及β2糖蛋白1抗体(β2-GPⅠ)与复发性流产(RSA)免疫失衡和妊娠结局的关系。方法 选取2021年8月至2024年8月郑州市第七人民医院收治的RSA患者102例为RSA组,同期无不良孕产史的健康女性102例为对照组,比较两组LA、ANA、ACA、β2-GPⅠ表达水平,免疫指标。Spearman分析RSA患者LA、ANA、ACA、β2-GPⅠ与免疫失衡的相关性。绘制受试者工作特征曲线(ROC)曲线分析LA、ANA、ACA、β2-GPⅠ对RSA患者妊娠结局的预测价值。结果 RSA组LA、ANA、ACA、β2-GPⅠ表达水平高于对照组,差异有统计学意义(P<0.05)。RSA组Th17/Treg、NK、CD4^(+)/CD8^(+)、CD56^(+)高于对照组,差异有统计学意义(P<0.05)。Spearman相关性分析显示,LA、ANA、ACA、β2-GPⅠ与辅助性T细胞17/调节性T细胞(Th17/Treg)、CD56^(+)、自然杀伤细胞(NK)、CD4^(+)/CD8^(+)呈正相关(P<0.05)。LA、ANA、ACA、β2-GPⅠ联合检测预测RSA患者妊娠结局的曲线下面积、敏感度、特异度为0.973、0.951、0.971,优于单一检测(P<0.05)。结论 LA、ANA、ACA、β2-GPⅠ可以作为RSA的早期诊断指标,与患者免疫失衡和妊娠结局密切相关。 展开更多
关键词 狼疮抗凝物 抗核抗体 抗心磷脂抗体 抗Β2糖蛋白1抗体 复发性流产
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An Approximation Method for Singular Trudinger-Moser Inequality
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作者 ZHU Maochun XU Wenyan JIANG Rou 《应用数学》 北大核心 2025年第1期64-70,共7页
In this paper,we construct a power type functional which is the approximation functional of the Singular Trudinger-Moser functional.Moreover,we obtain the concentration level of the functional and show it converges to... In this paper,we construct a power type functional which is the approximation functional of the Singular Trudinger-Moser functional.Moreover,we obtain the concentration level of the functional and show it converges to the concentration level of singular Trudinger-Moser functional on the unit ball. 展开更多
关键词 Singular Trudinger-Moser inequality approximation functional Concentration level
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Statistical analysis on the validity of the cold plasma approximation for chorus waves based on Van Allen Probe observations and their effects on radiation belt electrons
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作者 AoJun Ren Jiang Yu +2 位作者 Jing Wang ZuZheng Chen XiaoMan Liu 《Earth and Planetary Physics》 EI CAS 2025年第1期159-170,共12页
Theoretical analysis has demonstrated that the dispersion relation of chorus waves plays an essential role in the resonant interaction and energy transformation between the waves and magnetospheric electrons.Previous ... Theoretical analysis has demonstrated that the dispersion relation of chorus waves plays an essential role in the resonant interaction and energy transformation between the waves and magnetospheric electrons.Previous quantitative analyses often simplified the chorus dispersion relation by using the cold plasma assumption.However,the applicability of the cold plasma assumption is doubtful,especially during geomagnetic disturbances.We here present a systematic statistical analysis on the validity of the cold plasma dispersion relation of chorus waves based on observations from the Van Allen Probes over the period from 2012 to 2018.The statistical results show that the observed magnetic field intensities deviate substantially from those calculated from the cold plasma dispersion relation and that they become more pronounced with an increase in geomagnetic activity or a decrease in background plasma density.The region with large deviations is mainly concentrated in the nightside and expands in both the radial and azimuthal directions as the geomagnetic activity increases or the background plasma density decreases.In addition,the bounce-averaged electron scattering rates are computed by using the observed and cold plasma dispersion relation of chorus waves.Compared with usage of the cold plasma dispersion relation,usage of the observed dispersion relation considerably lowers the minimum resonant energy of electrons and lowers the scattering rates of electrons above tens of kiloelectronvolts but enhances those below.Furthermore,these differences are more pronounced with the enhancement of geomagnetic activity or the decrease in background plasma density. 展开更多
关键词 chorus waves cold plasma approximation dispersion relations scattering rates
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Exceptional Set for Diophantine Approximation with Primes of Two Squares and Three Biquadrates
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作者 LIU Minmin ZHANG Min LI Jinjiang 《数学进展》 北大核心 2025年第1期18-36,共19页
Suppose thatλ_(1),λ_(2),λ_(3),λ_(4),λ_(5)are nonzero real numbers,not all of the same sign,andλ_(1)/λ_(2)is irrational and algebraic.Let V be a well-spaced sequence,δ>0.In this paper,it is proved that,for ... Suppose thatλ_(1),λ_(2),λ_(3),λ_(4),λ_(5)are nonzero real numbers,not all of the same sign,andλ_(1)/λ_(2)is irrational and algebraic.Let V be a well-spaced sequence,δ>0.In this paper,it is proved that,for anyε>0,the number of v∈V with v≤N such that the following inequality|λ_(1)p_(1)~2+λ_(2)p_(2)~2+λ_(3)p_(3)~4+λ_(4)p_(4)~4+λ_5p_5~4-v|<v^(-δ)has no solution in prime variables p_(1),p_(2),p_(3),p_(4),p_(5)does not exceed O(N^(29/32+2δ+ε)). 展开更多
关键词 Diophantine approximation exponential sum Davenport-Heilbronn method prime variable
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Smoluchowski-Kramers Approximation for Stochastic Differential Equations under Discretization
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作者 Li Ge 《应用概率统计》 北大核心 2025年第4期622-635,共14页
This paper studies the Smoluchowski–Kramers approximation for a discrete-time dynamical system modeled as the motion of a particle in a force field.We show that the approximation holds for the drift-implicit Euler–M... This paper studies the Smoluchowski–Kramers approximation for a discrete-time dynamical system modeled as the motion of a particle in a force field.We show that the approximation holds for the drift-implicit Euler–Maruyama discretization and derive its convergence rate.In particular,the solution of the discretized system converges to the solution of the first-order limit equation in the mean-square sense,and this convergence is independent of the order in which the mass parameterμand the step size h tend to zero. 展开更多
关键词 stochastic differential equations Smoluchowski-Kramers approximation driftimplicit Euler-Maruyama scheme convergence rate
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A reconfigurable array with adaptive approximation using dual threshold accuracy
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作者 SHAN Rui SONG Yupeng LIAO Wang 《High Technology Letters》 2025年第3期226-237,共12页
With the growing demand for compute-intensive applications such as artificial intelligence(AI)and video processing,traditional reconfigurable array processors fail to meet the requirements of high-performance computin... With the growing demand for compute-intensive applications such as artificial intelligence(AI)and video processing,traditional reconfigurable array processors fail to meet the requirements of high-performance computing and related domains,primarily due to their high power consumption and low energy efficiency.To address this limitation,this paper proposes an accuracy-adaptive approxi-mate reconfigurable array architecture featuring preset dual thresholds and support for four computa-tional accuracy levels,enabling flexible adaptation to diverse application needs.The architecture in-tegrates a self-adaptive mechanism that dynamically adjusts computational precision based on real-time error threshold feedback.To evaluate the proposed architecture,the you only look once version 5(YOLOv5)deep neural network algorithm is parallelized and deployed on the approximate recon-figurable array.Experimental results demonstrate that the architecture achieves an 18.93%reduc-tion in power consumption compared with conventional reconfigurable structures operating in full-pre-cision mode.Additionally,the design exhibits superior energy efficiency and reduced computational resource utilization,thereby significantly enhancing the overall performance and applicability of reconfigurable array processors in power-sensitive scenarios. 展开更多
关键词 reconfigurable computing approximate computing low power ENERGY-EFFICIENT
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急性脑梗死伴认知功能障碍患者血清IL-8、MMP-9、ACA表达意义及影响因素分析
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作者 魏晓梅 张美玲 +1 位作者 邹玉环 郭洪升 《分子诊断与治疗杂志》 2025年第10期1936-1938,1942,共4页
目的探究急性脑梗死(ACI)伴认知功能障碍患者血清白细胞介素-8(IL-8)、基质金属蛋白酶-9(MMP-9)、抗心磷脂抗体(ACA)表达意义及认知功能障碍的影响因素。方法选取2022年6月至2024年4月青岛市胶州中心医院154例ACI患者,根据蒙特利尔认知... 目的探究急性脑梗死(ACI)伴认知功能障碍患者血清白细胞介素-8(IL-8)、基质金属蛋白酶-9(MMP-9)、抗心磷脂抗体(ACA)表达意义及认知功能障碍的影响因素。方法选取2022年6月至2024年4月青岛市胶州中心医院154例ACI患者,根据蒙特利尔认知评估量表(MOCA)评分不同分组,其中伴认知功能障碍(MOCA评分<26分)患者49例作为研究组,无认知功能障碍(MOCA评分≥26分)患者105例作为对照组。比较两组血清IL-8、MMP-9、ACA水平、MOCA、简易智能精神状态检查量表(MMSE)评分,分析血清IL-8、MMP-9、ACA水平诊断ACI伴认知功能障碍价值及与MOCA、MMSE评分的相关性,分析ACI伴认知功能障碍影响因素。结果研究组血清IL-8、MMP-9、ACA水平高于对照组,差异有统计学意义(P<0.05);血清IL-8、MMP-9、ACA联合诊断ACI伴认知功能障碍的曲线下面积(AUC)为0.882,大于单一诊断(P<0.05);研究组MOCA、MMSE评分低于对照组,差异有统计学意义(P<0.05);ACI伴认知功能障碍患者血清IL-8、MMP-9、ACA水平与MOCA、MMSE评分间存在负相关关系(P<0.05);经Logistic回归分析发现,年龄≥68岁、糖尿病、NIHSS评分>7分均为ACI伴认知功能障碍发生危险因素(P<0.05)。结论血清IL-8、MMP-9、ACA为ACI伴认知功能障碍发生危险因素,且能辅助临床诊断ACI伴认知功能障碍。 展开更多
关键词 急性脑梗死 认知功能障碍 白细胞介素-8 基质金属蛋白酶-9 抗心磷脂抗体
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On approximation of Bernstein-Stancu operators in movable interval
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作者 WAGN Feng-feng YU Dan-sheng 《Applied Mathematics(A Journal of Chinese Universities)》 2025年第1期85-101,共17页
In the present paper,we obtain the converse results of approximation of a newly introduced genuine Bernstein-Durrmeyer operators in movable interval.We also get the moments properties of an auxiliary operator which ha... In the present paper,we obtain the converse results of approximation of a newly introduced genuine Bernstein-Durrmeyer operators in movable interval.We also get the moments properties of an auxiliary operator which has its own independent values.The moments of the auxiliary operators play important roles in establishing the main result(Theorem 4). 展开更多
关键词 Bernstein-Stancu operators movable interval approximation rates Voronovskaja's asymptotic estimate
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A new oolitic content test method for green sand by repeated approximation
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作者 Yu-yang Qi Jian-xin Zhou +6 位作者 Xin Peng Si-yuan Pan Ya-jun Yin Xiao-yuan Ji Yuan-cai Li Peng-fei Lin Peng Wan 《China Foundry》 2025年第6期701-709,共9页
The reuse of green sand in casting production is hindered by the accumulation of oolitic deposits,primarily composed of clay binder with surface degradation,which may adversely affect the the moulding sand performance... The reuse of green sand in casting production is hindered by the accumulation of oolitic deposits,primarily composed of clay binder with surface degradation,which may adversely affect the the moulding sand performance.Currently,there is a lack of standardized methods for quantifying the oolitic content.Accurate measurement of oolitic content is of great significance to the reuse of green sand.Attempts to determine oolitic content using potassium hydroxide(KOH)and phosphoric acid(H_(3)PO_(4))methods encounter challenges due to their excessive reactions with SiO_(2) in the sand.In this study,an improved method for measuring the oolitic content of green sand with repeated approximations was proposed.This method judges the chemical activity of the sample surface through the change of its mass to accurately obtain the mass of the reaction oolitic deposits.The test result of the used sand samples from the foundry shows that the oolitic deposits are completely removed after reacting with KOH solution three times at 300℃ for 20 min.SEM and EDS also show that after three times of reactions,the surface of green sand becomes smooth and the content of Al-containing oolitic deposits is very low.This indicates that the method can accurately control the extent of the reaction.Implementation of this method at Huangshi Dongbei Casting Co.,Ltd.has yielded consistent and reliable test results,effectively mirroring variations in green sand oolitic content on the production line.This new method is expected to be widely adopted to improve the efficiency and quality of reused green sand in casting operations. 展开更多
关键词 green sand oolitic content repeated approximation reuse of green sand
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Adaptive polynomial approximation-based virtual coupled cooperative control for high-speed trains
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作者 Kai-Xiang Wang Ming-Yue Ren +1 位作者 Qian-Ling Wang Xue Lin 《Chinese Physics B》 2025年第10期589-596,共8页
Virtual coupling is a novel technology that enables trains to run closely together without physical connections through communication and automation systems.The paper addresses an adaptive polynomial approximation alg... Virtual coupling is a novel technology that enables trains to run closely together without physical connections through communication and automation systems.The paper addresses an adaptive polynomial approximation algorithm for the cooperative control of high-speed trains(HSTs)under virtual coupling.It aims to solve the cooperative tracking control problem of HST formation operations under various scenarios,including known and unknown parameters.To enable the HST formation system to achieve cooperative operation while ensuring an appropriate spacing distance,the tracking errors of displacement and speed throughout the entire operation converge to zero.The proposed control strategy focuses on adopting polynomial approximation to handle unknown parameters,which are estimated via adaptive laws.Additionally,the unknown parameters of the HSTs are estimated online through adaptive laws.Experimental results verify the effectiveness of this method. 展开更多
关键词 high-speed trains(HSTs) cooperative operation adaptive polynomial approximation virtual coupling
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Optimal convex approximations of qubit states based on l_(1)-norm of coherence
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作者 Li-Qiang Zhang Yan-Dong Du Chang-Shui Yu 《Chinese Physics B》 2025年第8期475-491,共17页
Determining the minimal distance between the target state and the convex combination of given states is a fundamental problem in quantum resource theory,offering critical guidance for experimental implementations.In t... Determining the minimal distance between the target state and the convex combination of given states is a fundamental problem in quantum resource theory,offering critical guidance for experimental implementations.In this paper,we embark on an in-depth exploration of the use of a quantum state prepared by the convex combination of given qubit states to optimally approximate the l_(1)-norm of coherence of the target quantum state,striving to make the prepared state and the target state as similar as possible.Here,we present the analytical solution for the optimal distance for any N given quantum states.We find that the optimal approximation problem for any N>4 quantum states can be transformed into an optimal approximation problem for no more than four quantum states,which not only significantly streamlines the problem but also proves advantageous for laboratories in terms of material conservation.Ultimately,a one-to-one comparison between the analytical and numerical solutions verifies the effectiveness of our approach. 展开更多
关键词 quantum information processing quantum resource theory quantum coherence optimal convex approximations
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Multi-Interval-Aggregation Failure Point Approximation for Remaining Useful Life Prediction
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作者 Linchuan Fan Xiaolong Chen +1 位作者 Shuo Li Yi Chai 《IEEE/CAA Journal of Automatica Sinica》 2025年第3期639-641,共3页
Dear Editor,This letter focuses on the remaining useful life(RUL)prediction task under limited labeled samples.Existing machine-learning-based RUL prediction methods for this task usually pay attention to mining degra... Dear Editor,This letter focuses on the remaining useful life(RUL)prediction task under limited labeled samples.Existing machine-learning-based RUL prediction methods for this task usually pay attention to mining degradation information to improve the prediction accuracy of degradation value or health indicator for the next epoch.However,they ignore the cumulative prediction error caused by iterations before reaching the failure point. 展开更多
关键词 remaining useful life prediction failure point degradation value health indicator multi interval aggregation failure point approximation machine learning based mining degradation information
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Fast Ion Gates without the Lamb-Dicke Approximation by Robust Quantum Optimal Control
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作者 Ran Liu Xiaodong Yang +2 位作者 Yiheng Lin Yao Lu Jun Li 《Chinese Physics Letters》 2025年第8期75-82,共8页
We present a robust quantum optimal control framework for implementing fast entangling gates on ion-trap quantum processors.The framework leverages tailored laser pulses to drive the multiple vibrational sidebands of ... We present a robust quantum optimal control framework for implementing fast entangling gates on ion-trap quantum processors.The framework leverages tailored laser pulses to drive the multiple vibrational sidebands of the ions to create phonon-mediated entangling gates and,unlike the state of the art,requires neither weakcoupling Lamb-Dicke approximation nor perturbation treatment.With the application of gradient-based optimal control,it enables finding amplitude-and phase-modulated laser control protocols that work without the Lamb-Dicke approximation,promising gate speeds on the order of microseconds comparable to the characteristic trap frequencies.Also,robustness requirements on the temperature of the ions and initial optical phase can be conveniently included to pursue high-quality fast gates against experimental imperfections.Our approach represents a step in speeding up quantum gates to achieve larger quantum circuits for quantum computation and simulation,and thus can find applications in near-future experiments. 展开更多
关键词 quantum optimal control framework gradient based optimal control quantum computation Lamb Dicke approximation fast ion gates tailored laser pulses entangling gates robust quantum optimal control
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ACA基因启动子的克隆及功能初探 被引量:6
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作者 刘召华 郭洪年 +1 位作者 郑光宇 田颖川 《生物工程学报》 CAS CSCD 北大核心 2005年第1期139-143,共5页
根据已知的ACA基因的 5 '端序列设计三个基因特异的反向引物 (GSP_1,GSP_2 ,GSP_3)分别与 11个简并引物 (AD1_AD11)配对 ,进行热不对称嵌套PCR(ThermalasymmetricinterlacedPCR ,TAIL_PCR)扩增 ,获得了ACA基因起始密码子上游约70 0b... 根据已知的ACA基因的 5 '端序列设计三个基因特异的反向引物 (GSP_1,GSP_2 ,GSP_3)分别与 11个简并引物 (AD1_AD11)配对 ,进行热不对称嵌套PCR(ThermalasymmetricinterlacedPCR ,TAIL_PCR)扩增 ,获得了ACA基因起始密码子上游约70 0bp的片段。为检测其表达特性 ,构建了该片段与Gus嵌合基因的表达载体pBpAG ,在真空条件下通过农杆菌介导 ,转化了植物的叶、果实、种子三种不同组织 ,Gus瞬时表达染色结果显示 ,该DNA片段具有种子特异的启动子活性。对该启动子的一些顺式元件进行了讨论。 展开更多
关键词 TAIL-PCR aca启动子 GUS 种子特异表达
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ACA离子取代凝胶多价离子置换性能研究 被引量:4
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作者 陈益清 孙多先 孙绵方 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2002年第6期133-136,共4页
考察了海藻酸 -壳聚糖 -海藻酸 ( ACA)离子取代凝胶对几种二价金属离子的置换行为。实验结果表明 ,海藻酸钙凝胶和海藻酸 -壳聚糖 -海藻酸凝胶微球 ( ACA- Ca)也能吸附 Pb2 +、Cu2 +和 Al3+,其中 Pb2 +、Cu2 +和 Al3+取代了凝胶中的 Ca2... 考察了海藻酸 -壳聚糖 -海藻酸 ( ACA)离子取代凝胶对几种二价金属离子的置换行为。实验结果表明 ,海藻酸钙凝胶和海藻酸 -壳聚糖 -海藻酸凝胶微球 ( ACA- Ca)也能吸附 Pb2 +、Cu2 +和 Al3+,其中 Pb2 +、Cu2 +和 Al3+取代了凝胶中的 Ca2 +,并且其置换速率要大大快于离子交换树脂 ,而其平衡取代量与 ACA微胶囊相当 ,因此 ,海藻酸钙凝胶也能作为离子吸附剂应用于吸附某些重金属离子。此外 ,Pb2 +也能置换海藻酸锌中的 Zn2 +,Ca2 +能置换海藻酸亚铁中的 Fe2 +。Pb2 +对海藻酸钙凝胶中的 Ca2 +的置换不仅包括Pb2 +对 Ca2 +的置换 ,还存在对 Pb2 展开更多
关键词 aca 离子 取代凝胶 多价离子 置换性能 研究 海藻酸
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AsAb、AcA与反复自然流产关系的探讨 被引量:11
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作者 陈永珍 朱旻 +1 位作者 张苏 李颖 《苏州大学学报(医学版)》 CAS 2002年第1期19-21,共3页
目的 探讨抗精子抗体 (AsAb) ,抗心磷脂抗体 (AcA)与反复自然流产的关系。方法 采用ELISA法测定反复自然流产病人血清中AsAb、AcA的含量。结果 流产组血清AsAb、AcA明显高于对照组 (P <0 .0 1) ,出现显著性差异。结论 抗精子抗... 目的 探讨抗精子抗体 (AsAb) ,抗心磷脂抗体 (AcA)与反复自然流产的关系。方法 采用ELISA法测定反复自然流产病人血清中AsAb、AcA的含量。结果 流产组血清AsAb、AcA明显高于对照组 (P <0 .0 1) ,出现显著性差异。结论 抗精子抗体和抗心磷脂抗体与反复自然流产有着密切的关系。 展开更多
关键词 AsAb aca 反复自然流产 抗精子抗体 抗心磷脂抗体
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β-葡萄糖苷酶ACA微胶囊固定化实验研究 被引量:2
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作者 周亚军 王淑杰 +2 位作者 苏丹 李宏谕 杨旭升 《现代化工》 CAS CSCD 北大核心 2009年第10期51-54,共4页
对壳聚糖为壁材的共价交联固定、海藻酸钠为壁材的包埋固定及壳聚糖和海藻酸钠共用的新型复合载体(ACA)固定的β-葡萄糖苷酶进行了对比研究,得出ACA微胶囊固定化的酶具有较好的催化活性、重复使用和低温贮藏性能。醋酸和戊二醛及CaCl2... 对壳聚糖为壁材的共价交联固定、海藻酸钠为壁材的包埋固定及壳聚糖和海藻酸钠共用的新型复合载体(ACA)固定的β-葡萄糖苷酶进行了对比研究,得出ACA微胶囊固定化的酶具有较好的催化活性、重复使用和低温贮藏性能。醋酸和戊二醛及CaCl2的浓度、壳聚糖和海藻酸钠用量、引发和交联时间对ACA微胶囊固定酶的形态和性能影响较大,葡萄糖转化率随醋酸与戊二醛和CaCl2浓度的增加、壳聚糖和海藻酸钠用量的增大、交联和引发时间的延长呈先增大后减小的变化趋势,并于不同特定值达到最大。 展开更多
关键词 Β-葡萄糖苷酶 aca微胶囊固定化 烷基糖苷 葡萄糖转化率
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情报学学科结构的ABCA及ACA对比研究——以2000-2010年数据为例 被引量:5
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作者 朱红艳 章丹 《情报杂志》 CSSCI 北大核心 2014年第8期76-83,共8页
以SCI&SSCI 2000-2010年间情报学的相关数据为样本,结合传统的ACA(作者共被引)方法,以ABCA(作者文献耦合分析)方法为研究视角,探析2000-2010情报学的学科结构,并进行ABCA与ACA的比较研究。研究探测到了情报学的几位具有较强研究活... 以SCI&SSCI 2000-2010年间情报学的相关数据为样本,结合传统的ACA(作者共被引)方法,以ABCA(作者文献耦合分析)方法为研究视角,探析2000-2010情报学的学科结构,并进行ABCA与ACA的比较研究。研究探测到了情报学的几位具有较强研究活力以及广泛影响力的学者,如Thelwall,M、Leydesdorff,L、Cronin,B、White,HD、Meho,LI等。探寻到情报学的7个主要研究主题:科学计量学、网络资源管理与配置、信息检索、信息系统、知识管理、用户交互与服务、科学评价,其中科学计量学和网络资源管理与配置是2个主流研究主题;研究认为,各研究主题之间的融合还有待于进一步加强。在研究主题探测方面,ABCA是以当前活跃的作者的角度进行分析;ACA则是以对情报学产生持续影响的作者为角度。ABCA可以探寻到更多的研究主题,但ABCA与ACA探测到的主题内容没有太大出入。 展开更多
关键词 ABCA aca 情报学 学科结构
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GL-7-ACA酰化酶基因片段的酶谱分析及基因定位 被引量:3
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作者 杨蕴刘 恽定芳 +1 位作者 彭惠琳 焦瑞身 《生物工程学报》 CAS CSCD 北大核心 1992年第1期15-22,共8页
本文报道了从假单胞菌130菌株(Pseudomonas sp.130)染色体上克隆得到的6.8kb的GL-7-ACA酰化酶基因片段的限制酶谱,基因定位以及在不同的大肠杆菌基因启动子控制下酰化酶基因的表达水平。结果表明,所克隆的片段上,不存在EcoR Ⅰ、Hind Ⅱ... 本文报道了从假单胞菌130菌株(Pseudomonas sp.130)染色体上克隆得到的6.8kb的GL-7-ACA酰化酶基因片段的限制酶谱,基因定位以及在不同的大肠杆菌基因启动子控制下酰化酶基因的表达水平。结果表明,所克隆的片段上,不存在EcoR Ⅰ、Hind Ⅱ、Cla Ⅰ切点,分别具有一个Hpa Ⅰ、两个Xho Ⅰ、三个BamH Ⅰ以及四个Pst Ⅰ切点,同时初步确定了这些酶切位点之间的相对位置。经过一系列次级克隆研究,GL-7-ACA酰化酶基因已被定位在3.0kb的B_2-B_3-Hpa Ⅰ片段上。实验比较了以pACYC184、pDR540、pUC10等为载体的次级克隆株(分别为pMR9、pMR10和pMR11)在大肠杆菌中酰化酶基因的表达水平,测定数据表明tac启动子的启动活力比tet启动子强,即pMR10的产酶量比pMR9高一倍,而当tac启动子前再串接一个lac启动子时(pMR11),产酶水平并不进一步提高。本文还对假单胞菌基因在大肠杆菌中的表达进行了讨论。 展开更多
关键词 基因定位 基因表达 GL7aca酰化酶
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我国情报学研究分析:以ACA为方法 被引量:59
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作者 马费成 宋恩梅 《情报学报》 CSSCI 北大核心 2006年第3期259-268,共10页
ACA属于同被引分析法,其全称是作者同被引分析(Author Co—citation Analysis)。这种方法从特定学科或特定领域的核心著者的同被引入手,探讨学科结构和流派等问题。本文以ACA为方法,选取1994—2005年间的数据,对我国情报学领域的... ACA属于同被引分析法,其全称是作者同被引分析(Author Co—citation Analysis)。这种方法从特定学科或特定领域的核心著者的同被引入手,探讨学科结构和流派等问题。本文以ACA为方法,选取1994—2005年间的数据,对我国情报学领域的核心著者进行了同被引分析,以此揭示出我国情报学学科的结构和研究状况。 展开更多
关键词 情报学研究 aca分析 学术集团 中国 作者同被引分析 核心著者
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