There are many problems in English Vocabulary Teaching in rural primary schools. In order to solve these problems, create a situation suitable for rural children's English learning, more in line with rural childre...There are many problems in English Vocabulary Teaching in rural primary schools. In order to solve these problems, create a situation suitable for rural children's English learning, more in line with rural children’s life experience, and design activities to improve learning interest and efficiency, three English teachers from two rural primary schools in Jianyang City, Sichuan Province (Pingwu Jiuyi school and Pingxi Jiuyi school) conducted the following research: 1. Study two rural schools, grade 3-5, and nine class farmers English vocabulary learning of village students. 2. Combined with the materials about the creation of English situation and activity design in primary schools, we discuss how to create English vocabulary activity teaching situation and activity plan suitable for rural children after studying the teaching materials. Then, using the method of collective lesson preparation, this paper sorts out the vocabulary teaching plan for grade 3-5 and puts it into practice. 3. Through the data analysis of the experimental class and the control class, it is concluded that these programs can effectively improve the interest and effect of rural primary school English learning.展开更多
The title compound has been synthesized by the addition reaction of N-（4-cyanopyrazole-3-yl）-3,5-difluorophenyl-imine and diisopropyl phosphate. Its structure was confirmed by means of IR, ^1H NMR and elemental anal...The title compound has been synthesized by the addition reaction of N-（4-cyanopyrazole-3-yl）-3,5-difluorophenyl-imine and diisopropyl phosphate. Its structure was confirmed by means of IR, ^1H NMR and elemental analysis. The single-crystal structure of the title compound was determined by X-ray crystallography. The compound crystallizes in monoclinic, space group C2/c with a = 18.9959（14）, b = 9.2212（7）, c = 22.1108（16）A^°, β= 90.1540（10）°, V = 3873.0（5） A^°^3, Dc = 1.366 g/cm^3, Z = 8, μ = 0.185, F（000） = 1664, and the final R = 0.0503 and wR = 0.1539 for 2996 observed reflections （I 〉 2σ（I））. The results demonstrate that the dihedral angle between the pyrazole and benzene rings is 105.5°, and there is a full delocalized pyrazole system with sp^2 hydridization of N（3）. The crystal structure is stabilized by two intermolecular hydrogen bonds of N（1）-H（1）…O（3） and N（3）-H（3A）…N（4）. The preliminary biological test shows that the title compound has a moderate antifungal activity.展开更多
OBJECTIVE Panax ginseng C.A.Meyer(ginseng)is a well-known medicinal plant worldwide and a key ingredient in many commercially-available health products.It is used as a tonic for invigoration and for tification in time...OBJECTIVE Panax ginseng C.A.Meyer(ginseng)is a well-known medicinal plant worldwide and a key ingredient in many commercially-available health products.It is used as a tonic for invigoration and for tification in times of fatigue and debility or declining capacity for work and concentration.Previous in-house study has surveyed over three hundred ginseng and ginseng products(including P.ginseng,P.quinquefolius,P.notoginseng,P.pseudoginseng)available in Singapore.This review presents an overview of the pharmacological activities and herb-drug interactions of P.ginseng and its ginsenosides.METHODS Literature searches of PubMed and ScienceDirect were done to identify pharmacological activities and herb-drug interactions of P.ginseng,its extracts and its chemical components,including ginsenosides.Studies of whole plant extracts include both White ginseng and Red ginseng.The studies for the pharmacological activities of whole plant extract were limited to those published from 2009 to 2015.There was no restriction on the time frame of other studies.Terms such as″P.ginseng″,″Ginsenosides″were searched.Studies found included in vitro assays,in vivo animal studies,human clinical trials as well as individual case reports.RESULTS A total of 112 studies were found on whole plant extracts and 257 studies on its individual components.Whole plant extracts of ginseng were found to possess over fifty different pharmacological activities,while its individual components exhibit parts of this spectrum.P.ginseng was found to interact with drugs such as 5-fluorouracil,irinotecan,mitomycin C,docetaxel,cisplatin,alcohol,midazolam,warfarin,phenelzine,raltegravir and imatinib.CONCLUSION P.ginseng and its components exhibit a wide range of pharmacological activities and interact with some drugs.There remain much opportunities for future research.展开更多
Initiated by Chinese Red Cross Foundation and sponsored by American .General Business Association, Chinese Nuwa （a goddess-creator of the Chinese nation） Culture Large-scale Activities for Public Interests undertake...Initiated by Chinese Red Cross Foundation and sponsored by American .General Business Association, Chinese Nuwa （a goddess-creator of the Chinese nation） Culture Large-scale Activities for Public Interests undertaken by Beijing Absolute Challenge International Advertising Co., Ltd. has recently commenced in an all-round way. A grand ceremony will be held at Nuwa Plaza in Shexian County, Hebei Province on Septemper 24, 2007.展开更多
Objective： To investigate the relationship between emotional status, cold-dry environment and long-term immune responses to the stressors, and the potential pathological mechanisms between causative factors of abnorm...Objective： To investigate the relationship between emotional status, cold-dry environment and long-term immune responses to the stressors, and the potential pathological mechanisms between causative factors of abnormal Savda syndrome （ASS） and the susceptibility to disease; thus to clarify the ASS, and secondly to identify the optimal ASS animal model for further studies on traditional Uighur therapeutical formulations. Methods： Sixty mice were randomly and equally divided into 4 groups： control and 3 stress groups. The cold-dry environment was applied by keeping the mice in a climatic chamber. The emotional stress was induced by the application of the repeated electric foot-shocks in the electric foot-shock apparatus. The mice of the combined stress group underwent the repeated electric foot-shock treatment before being housed in the climatic chamber. The experimental routine was repeated for 21 days. In order to look into endocrine and immune stress responses, ELISA was used to determine the serum levels of the hormones corticotropin- releasing hormone （CRH）, adrenocorticotropic hormone （ACTH）, Beta-endorphin （13-END） and corticosterone （CORT）, of the cytokines interleukin 2 （IL-2）, interleukin 6 （IL-6）, interferon-gamma （INF- ~/） and tumor necrosis factor-alpha （TNF-or）, and of the immunoglobulins immunoglobulin A （IgA）, immunoglobulin M （IgM） and immunoglobulin G （IgG）. Lymphocyte subsets were analyzed in duplicate in order to determine differences in the T cell ratio. Results： In the cold-dry environment group, the serum levels of CRH, ACTH and CORT were significantly higher than those of the control group, whereas serum 13 -END was not found significantly different. In both the repeated electric foot-shock group as well as in the combined stress group the serum levels of CRH, ACTH, 13 -END and CORT were significantly higher. Compared to the control animals, the serum concentration of INF-,y was significantly lower in all three different stress groups. The serum level of IL-2 was decreased in the combined stress group whereas the serum TNF-~x level was significantly higher. The serum IgG level was significantly higher in all three stress groups, whereas the IgA level was lower in both chronic electric foot-shock group and combined stress group. The IgM level was found significantly higher in the combined stress group only. The percentage of CD4＋ cells in peripheral blood was dramatically decreased in mice exposed to cold- dry environment, chronic electric foot-shock and combined stress, whereas the percentage of the CD8＊ subset was not significantly different. The CD4＊/CD8~ ratios were markedly lower in both cold-dry environment group and combined stress group. （Conclusions： Combined stress can cause hyperactivity of the HPA axis, and an imbalance in the Thl/Th2 cell subset may contribute to illustrate the partial pathological mechanisms of ASS. This study identified this animal model of a combination of physical and emotional stress as an optimal model for further studies on ASS and relative therapies.展开更多
文摘There are many problems in English Vocabulary Teaching in rural primary schools. In order to solve these problems, create a situation suitable for rural children's English learning, more in line with rural children’s life experience, and design activities to improve learning interest and efficiency, three English teachers from two rural primary schools in Jianyang City, Sichuan Province (Pingwu Jiuyi school and Pingxi Jiuyi school) conducted the following research: 1. Study two rural schools, grade 3-5, and nine class farmers English vocabulary learning of village students. 2. Combined with the materials about the creation of English situation and activity design in primary schools, we discuss how to create English vocabulary activity teaching situation and activity plan suitable for rural children after studying the teaching materials. Then, using the method of collective lesson preparation, this paper sorts out the vocabulary teaching plan for grade 3-5 and puts it into practice. 3. Through the data analysis of the experimental class and the control class, it is concluded that these programs can effectively improve the interest and effect of rural primary school English learning.
基金supported by the Youth Foundation of Jiangxi Agricultural University (No. 20051527)
文摘The title compound has been synthesized by the addition reaction of N-（4-cyanopyrazole-3-yl）-3,5-difluorophenyl-imine and diisopropyl phosphate. Its structure was confirmed by means of IR, ^1H NMR and elemental analysis. The single-crystal structure of the title compound was determined by X-ray crystallography. The compound crystallizes in monoclinic, space group C2/c with a = 18.9959（14）, b = 9.2212（7）, c = 22.1108（16）A^°, β= 90.1540（10）°, V = 3873.0（5） A^°^3, Dc = 1.366 g/cm^3, Z = 8, μ = 0.185, F（000） = 1664, and the final R = 0.0503 and wR = 0.1539 for 2996 observed reflections （I 〉 2σ（I））. The results demonstrate that the dihedral angle between the pyrazole and benzene rings is 105.5°, and there is a full delocalized pyrazole system with sp^2 hydridization of N（3）. The crystal structure is stabilized by two intermolecular hydrogen bonds of N（1）-H（1）…O（3） and N（3）-H（3A）…N（4）. The preliminary biological test shows that the title compound has a moderate antifungal activity.
基金The project supported by Lee Foundation Grant(TCH and KHL,R-184-000-200-720)and research scholarship(WHN)
文摘OBJECTIVE Panax ginseng C.A.Meyer(ginseng)is a well-known medicinal plant worldwide and a key ingredient in many commercially-available health products.It is used as a tonic for invigoration and for tification in times of fatigue and debility or declining capacity for work and concentration.Previous in-house study has surveyed over three hundred ginseng and ginseng products(including P.ginseng,P.quinquefolius,P.notoginseng,P.pseudoginseng)available in Singapore.This review presents an overview of the pharmacological activities and herb-drug interactions of P.ginseng and its ginsenosides.METHODS Literature searches of PubMed and ScienceDirect were done to identify pharmacological activities and herb-drug interactions of P.ginseng,its extracts and its chemical components,including ginsenosides.Studies of whole plant extracts include both White ginseng and Red ginseng.The studies for the pharmacological activities of whole plant extract were limited to those published from 2009 to 2015.There was no restriction on the time frame of other studies.Terms such as″P.ginseng″,″Ginsenosides″were searched.Studies found included in vitro assays,in vivo animal studies,human clinical trials as well as individual case reports.RESULTS A total of 112 studies were found on whole plant extracts and 257 studies on its individual components.Whole plant extracts of ginseng were found to possess over fifty different pharmacological activities,while its individual components exhibit parts of this spectrum.P.ginseng was found to interact with drugs such as 5-fluorouracil,irinotecan,mitomycin C,docetaxel,cisplatin,alcohol,midazolam,warfarin,phenelzine,raltegravir and imatinib.CONCLUSION P.ginseng and its components exhibit a wide range of pharmacological activities and interact with some drugs.There remain much opportunities for future research.
文摘Initiated by Chinese Red Cross Foundation and sponsored by American .General Business Association, Chinese Nuwa （a goddess-creator of the Chinese nation） Culture Large-scale Activities for Public Interests undertaken by Beijing Absolute Challenge International Advertising Co., Ltd. has recently commenced in an all-round way. A grand ceremony will be held at Nuwa Plaza in Shexian County, Hebei Province on Septemper 24, 2007.
基金Supported by the National Natural Science Foundation of China (No.30525023)
文摘Objective： To investigate the relationship between emotional status, cold-dry environment and long-term immune responses to the stressors, and the potential pathological mechanisms between causative factors of abnormal Savda syndrome （ASS） and the susceptibility to disease; thus to clarify the ASS, and secondly to identify the optimal ASS animal model for further studies on traditional Uighur therapeutical formulations. Methods： Sixty mice were randomly and equally divided into 4 groups： control and 3 stress groups. The cold-dry environment was applied by keeping the mice in a climatic chamber. The emotional stress was induced by the application of the repeated electric foot-shocks in the electric foot-shock apparatus. The mice of the combined stress group underwent the repeated electric foot-shock treatment before being housed in the climatic chamber. The experimental routine was repeated for 21 days. In order to look into endocrine and immune stress responses, ELISA was used to determine the serum levels of the hormones corticotropin- releasing hormone （CRH）, adrenocorticotropic hormone （ACTH）, Beta-endorphin （13-END） and corticosterone （CORT）, of the cytokines interleukin 2 （IL-2）, interleukin 6 （IL-6）, interferon-gamma （INF- ~/） and tumor necrosis factor-alpha （TNF-or）, and of the immunoglobulins immunoglobulin A （IgA）, immunoglobulin M （IgM） and immunoglobulin G （IgG）. Lymphocyte subsets were analyzed in duplicate in order to determine differences in the T cell ratio. Results： In the cold-dry environment group, the serum levels of CRH, ACTH and CORT were significantly higher than those of the control group, whereas serum 13 -END was not found significantly different. In both the repeated electric foot-shock group as well as in the combined stress group the serum levels of CRH, ACTH, 13 -END and CORT were significantly higher. Compared to the control animals, the serum concentration of INF-,y was significantly lower in all three different stress groups. The serum level of IL-2 was decreased in the combined stress group whereas the serum TNF-~x level was significantly higher. The serum IgG level was significantly higher in all three stress groups, whereas the IgA level was lower in both chronic electric foot-shock group and combined stress group. The IgM level was found significantly higher in the combined stress group only. The percentage of CD4＋ cells in peripheral blood was dramatically decreased in mice exposed to cold- dry environment, chronic electric foot-shock and combined stress, whereas the percentage of the CD8＊ subset was not significantly different. The CD4＊/CD8~ ratios were markedly lower in both cold-dry environment group and combined stress group. （Conclusions： Combined stress can cause hyperactivity of the HPA axis, and an imbalance in the Thl/Th2 cell subset may contribute to illustrate the partial pathological mechanisms of ASS. This study identified this animal model of a combination of physical and emotional stress as an optimal model for further studies on ASS and relative therapies.
