A crossbreeding program was established in 2019 to address the declining Crassostrea gigas harvests caused by Pacific Oyster Mortality Syndrome(POMS).As a part of the program,this study was performed to estimate the g...A crossbreeding program was established in 2019 to address the declining Crassostrea gigas harvests caused by Pacific Oyster Mortality Syndrome(POMS).As a part of the program,this study was performed to estimate the genetic structure underlying phenotypic variation.Fifteen complete diallel crossings of C.gigas and C.angulata,comprising 60 full-sib families,were used to evaluate the general combining ability(GCA)and specific combining ability(SCA),as well as genotype and environment interactions for shell height(SH),summer survival(SS),and thermal tolerance(TT)of reciprocal hybrids GA(C.gigas♀×C.angulata♂)and AG(C.angulata♀×C.gigas♂)grown in Rongcheng and Rushan,Shandong Province,China.The results suggested that heterosis of the reciprocal hybrids was evident for SH,SS,and TT.The hybrid GA had larger heterosis than AG in both testing environments,and can be a potential donor in the breeding program.The male C.gigas had better GCA for SH in Rongcheng,whereas male C.angulata was a good general combiner for SS and TT in both Rongcheng and Rushan.The estimate of SCA was much higher than GCA for SH and lower than GCA for TT.To harness both additive and non-additive genetic effects,combination breed-ing could be taken to develop hybrid varieties possessing both thermal tolerance and fast-growing traits.The positive correlations between SH and TT suggested that these traits could be improved simultaneously.The significant G×E interactions demonstrated the importance to undertake site-specific breeding programs in different environments.Overall,this study can provide essential information for developing crossbreeding strategies for the oyster farming industry.展开更多
Background: Sickle cell anemia(SCA), a genetic hemoglobin disorder, suggests essential inner ear compromise and poor auditory processing. In humans, auditory processing differs physiologically between males and female...Background: Sickle cell anemia(SCA), a genetic hemoglobin disorder, suggests essential inner ear compromise and poor auditory processing. In humans, auditory processing differs physiologically between males and females, possibly true for SCA due to gender-specific disease pathophysiological changes. Objective: To investigate gender differences in psychoacoustical abilities, and speech perception in noise in SCA individuals and further compare with normal healthy(NH) population. Methods: 80 SCA and 80 NH normal-hearing participants aged 15-40 years were included and further grouped based on gender. Auditory discrimination for frequency, intensity, and duration at 500Hz and 4000Hz;temporal processing(Gap detection threshold & Modulation Detection Threshold) and Speech Perception In Noise(SPIN) at 0d BSNR tests were evaluated and compared between males and females of SCA and NH population. Results: SCA performed poorer compared to NH for all experimental measures. In the NH population, males performed poorer than females in psychoacoustical measures whereas within the SCA population, the reverse was true. Female participants performed better in the SPIN test in both populations. Conclusions: The adverse impact of SCA on the auditory system due to circulatory changes might cause poorer performance in SCA. Poorer performance by Female SCA is possibly due to the contrary impact of lower Hb level overlying Sickle disease.Estrogen levels and gender preference in auditory processing might lead to better performance by females within the NH population. SPIN performance depends on different attentional demands and sensorimotor processing strategies in noise beyond psychoacoustical processing may lead to better female performance in both populations.展开更多
Objective:To assess the teaching efficacy of clinical instructors for MNS postgraduates,this study aims to gather insights into clinical educators’perceptions concerning MNS postgraduate training and identify key com...Objective:To assess the teaching efficacy of clinical instructors for MNS postgraduates,this study aims to gather insights into clinical educators’perceptions concerning MNS postgraduate training and identify key competencies required for effective teaching.Methods:This study utilized a cross-sectional design.An online questionnaire survey was distributed among clinical faculty members engaged in the education of MNS postgraduates.The survey addressed 4 areas:general teaching conditions,perceptions regarding training for MNS postgraduates,core competencies expected from clinical teachers,and implementation strategies for delivering clinical instruction tailored to these graduates.Results:A total of 143 clinical teachers supervising MNS postgraduates completed the questionnaire.Of these respondents,101(70.62%)held a bachelor’s degree while 42(29.37%)possessed a master’s degree.Although these clinicians demonstrated certain core competencies,they exhibited lower proficiency in understanding trends related to scientific advancements and current research priorities along with limited research capabilities 4.00(3.00,4.00).Notably,>95.8%of teachers recognized differences between the 2 categories of postgraduate students;only 4.2%were completely unaware of such distinctions.There was no statistically significant relationship between the demographic data of clinical educators and their core competencies(P>0.05).Conclusions:This study revealed no significant correlation between the general characteristics of clinical teachers and the core competencies of MNS postgraduates.Additionally,we identified a lack of effective communication and collaboration between MNS postgraduate supervisors and clinical educators.The findings from this research offer valuable insights for further investigation into the factors that influence the core competencies of clinical teachers,as well as strategies to enhance the clinical teaching standards for MNS postgraduates.展开更多
Geographical background and dispersal ability may strongly influence assemblage dissimilarity;however,these aspects have generally been overlooked in previous large-scale beta diversity studies.Here,we examined whethe...Geographical background and dispersal ability may strongly influence assemblage dissimilarity;however,these aspects have generally been overlooked in previous large-scale beta diversity studies.Here,we examined whether the patterns and drivers of taxonomic beta diversity(TBD)and phylogenetic beta diversity(PBD)of breeding birds in China vary across(1)regions on both sides of the Hu Line,which demarcates China’s topographical,climatic,economic,and social patterns,and(2)species with different dispersal ability.TBD and PBD were calculated and partitioned into turnover and nestedness components using a moving window approach.Variables representing climate,habitat heterogeneity,and habitat quality were employed to evaluate the effects of environmental filtering.Spatial distance was considered to assess the impact of dispersal limitation.Variance partitioning analysis was applied to assess the relative roles of these variables.In general,the values of TBD and PBD were high in mountainous areas and were largely determined by environmental filtering.However,different dominant environmental filters on either side of the Hu Line led to divergent beta diversity patterns.Specifically,climate-driven species turnover and habitat heterogeneity-related species nestedness dominated the regions east and west of the line,respectively.Additionally,bird species with stronger dispersal ability were more susceptible to environmental filtering,resulting in more homogeneous assemblages.Our results indicated that regions with distinctive geographical backgrounds may present different ecological factors that lead to divergent assemblage dissimilarity patterns,and dispersal ability determines the response of assemblages to these ecological factors.Identifying a single universal explanation for the observed pattern without considering these aspects may lead to simplistic or incomplete conclusions.Consequently,a comprehensive understanding of large-scale beta diversity patterns and effective planning of conservation strategies necessitate the consideration of both geographical background and species dispersal ability.展开更多
China has allocated a combined 10 trillion yuan(US$1.39 trillion)in new fiscal funding to replace hidden local government debt,or liabilities that local governments do not o"cially report.This marks one of the la...China has allocated a combined 10 trillion yuan(US$1.39 trillion)in new fiscal funding to replace hidden local government debt,or liabilities that local governments do not o"cially report.This marks one of the largest moves of its kind in recent years.The Standing Committee of the National People’s Congress(NPC),China’s top legislative body,approved a bill that raises the ceiling on local government debt by 6 trillion yuan(US$834 billion)to address existing hidden debt,Xu Hongcai,deputy head of the NPC’s Financial and Economic Affairs Committee,said at a press conference after the Standing Committee of the 14th NPC concluded its 12th session in Beijing on November 8.展开更多
Engaging students in the examination of the local significance of newly established historic districts within real-life contexts serves as a crucial method for exploring the geographical practical ability.This study u...Engaging students in the examination of the local significance of newly established historic districts within real-life contexts serves as a crucial method for exploring the geographical practical ability.This study utilizes Dongyi Town in Rizhao City as a case study,employing text analysis,field research,and interviews.It draws upon the theoretical frameworks of place and placelessness,while integrating research resources from two distinct perspectives:the evolution of the landscape and the emotional attitudes of various subjects towards the neighborhood.Students will be encouraged to investigate the environmental characteristics of the natural geography inherent in Dongyi Town,the current state of urban development and its implications for the local economy,culture,and environment through field visits and firsthand experiences.By employing the theory of place and placelessness,students will gain a deeper understanding of the underlying subjects and values associated with the landscape.Furthermore,they will learn to utilize this theoretical framework to reflect on the significance of districts to individuals,thereby enhancing their geographical practical abilities.展开更多
This study empirically analyzes the application effect of the integration of medical and educational models in cultivating professional abilities in traditional Chinese medicine rehabilitation techniques.The research ...This study empirically analyzes the application effect of the integration of medical and educational models in cultivating professional abilities in traditional Chinese medicine rehabilitation techniques.The research subjects are 100 students from the Traditional Chinese Medicine Rehabilitation Technology major at Y school.Through questionnaire scores,practical training results,and interview data,this study explores the outcomes of this integrated approach.The findings reveal that students in the experimental group significantly outperform those in the control group in terms of practical operation skills,professional responsibility,and communication and collaboration skills.This research confirms the notable role of the medical-educational integration model in enhancing the professional skills and accomplishments of students majoring in traditional Chinese medicine rehabilitation,providing a scientific basis for vocational education reform and the cultivation of rehabilitation technical talents.展开更多
基金founded by the National Key R&D Program of China(No.2022YFD2400305)the Earmarked Fund for Agriculture Seed Improvement Project of Shandong Province(Nos.2022LZGCQY010,2021LZGC027 and 2021ZLGX03)the China Agriculture Research System Project(No.CARS-49)。
文摘A crossbreeding program was established in 2019 to address the declining Crassostrea gigas harvests caused by Pacific Oyster Mortality Syndrome(POMS).As a part of the program,this study was performed to estimate the genetic structure underlying phenotypic variation.Fifteen complete diallel crossings of C.gigas and C.angulata,comprising 60 full-sib families,were used to evaluate the general combining ability(GCA)and specific combining ability(SCA),as well as genotype and environment interactions for shell height(SH),summer survival(SS),and thermal tolerance(TT)of reciprocal hybrids GA(C.gigas♀×C.angulata♂)and AG(C.angulata♀×C.gigas♂)grown in Rongcheng and Rushan,Shandong Province,China.The results suggested that heterosis of the reciprocal hybrids was evident for SH,SS,and TT.The hybrid GA had larger heterosis than AG in both testing environments,and can be a potential donor in the breeding program.The male C.gigas had better GCA for SH in Rongcheng,whereas male C.angulata was a good general combiner for SS and TT in both Rongcheng and Rushan.The estimate of SCA was much higher than GCA for SH and lower than GCA for TT.To harness both additive and non-additive genetic effects,combination breed-ing could be taken to develop hybrid varieties possessing both thermal tolerance and fast-growing traits.The positive correlations between SH and TT suggested that these traits could be improved simultaneously.The significant G×E interactions demonstrated the importance to undertake site-specific breeding programs in different environments.Overall,this study can provide essential information for developing crossbreeding strategies for the oyster farming industry.
文摘Background: Sickle cell anemia(SCA), a genetic hemoglobin disorder, suggests essential inner ear compromise and poor auditory processing. In humans, auditory processing differs physiologically between males and females, possibly true for SCA due to gender-specific disease pathophysiological changes. Objective: To investigate gender differences in psychoacoustical abilities, and speech perception in noise in SCA individuals and further compare with normal healthy(NH) population. Methods: 80 SCA and 80 NH normal-hearing participants aged 15-40 years were included and further grouped based on gender. Auditory discrimination for frequency, intensity, and duration at 500Hz and 4000Hz;temporal processing(Gap detection threshold & Modulation Detection Threshold) and Speech Perception In Noise(SPIN) at 0d BSNR tests were evaluated and compared between males and females of SCA and NH population. Results: SCA performed poorer compared to NH for all experimental measures. In the NH population, males performed poorer than females in psychoacoustical measures whereas within the SCA population, the reverse was true. Female participants performed better in the SPIN test in both populations. Conclusions: The adverse impact of SCA on the auditory system due to circulatory changes might cause poorer performance in SCA. Poorer performance by Female SCA is possibly due to the contrary impact of lower Hb level overlying Sickle disease.Estrogen levels and gender preference in auditory processing might lead to better performance by females within the NH population. SPIN performance depends on different attentional demands and sensorimotor processing strategies in noise beyond psychoacoustical processing may lead to better female performance in both populations.
基金supported by the Medical Education Research Initiative of Henan Province,grant funded by the Henan Provincial Health Commission(No.Wjlx2022186).
文摘Objective:To assess the teaching efficacy of clinical instructors for MNS postgraduates,this study aims to gather insights into clinical educators’perceptions concerning MNS postgraduate training and identify key competencies required for effective teaching.Methods:This study utilized a cross-sectional design.An online questionnaire survey was distributed among clinical faculty members engaged in the education of MNS postgraduates.The survey addressed 4 areas:general teaching conditions,perceptions regarding training for MNS postgraduates,core competencies expected from clinical teachers,and implementation strategies for delivering clinical instruction tailored to these graduates.Results:A total of 143 clinical teachers supervising MNS postgraduates completed the questionnaire.Of these respondents,101(70.62%)held a bachelor’s degree while 42(29.37%)possessed a master’s degree.Although these clinicians demonstrated certain core competencies,they exhibited lower proficiency in understanding trends related to scientific advancements and current research priorities along with limited research capabilities 4.00(3.00,4.00).Notably,>95.8%of teachers recognized differences between the 2 categories of postgraduate students;only 4.2%were completely unaware of such distinctions.There was no statistically significant relationship between the demographic data of clinical educators and their core competencies(P>0.05).Conclusions:This study revealed no significant correlation between the general characteristics of clinical teachers and the core competencies of MNS postgraduates.Additionally,we identified a lack of effective communication and collaboration between MNS postgraduate supervisors and clinical educators.The findings from this research offer valuable insights for further investigation into the factors that influence the core competencies of clinical teachers,as well as strategies to enhance the clinical teaching standards for MNS postgraduates.
基金supported by the National Natural Science Foundation of China(31901220)Science and Technology Planning Project of Guangdong Province,China(2019B121202004)+1 种基金Guangdong Basic and Applied Basic Research Foundation(2021A1515110744)Forestry Administration of Guangdong Province(DFGP Project of Fauna of Guangdong-202115)。
文摘Geographical background and dispersal ability may strongly influence assemblage dissimilarity;however,these aspects have generally been overlooked in previous large-scale beta diversity studies.Here,we examined whether the patterns and drivers of taxonomic beta diversity(TBD)and phylogenetic beta diversity(PBD)of breeding birds in China vary across(1)regions on both sides of the Hu Line,which demarcates China’s topographical,climatic,economic,and social patterns,and(2)species with different dispersal ability.TBD and PBD were calculated and partitioned into turnover and nestedness components using a moving window approach.Variables representing climate,habitat heterogeneity,and habitat quality were employed to evaluate the effects of environmental filtering.Spatial distance was considered to assess the impact of dispersal limitation.Variance partitioning analysis was applied to assess the relative roles of these variables.In general,the values of TBD and PBD were high in mountainous areas and were largely determined by environmental filtering.However,different dominant environmental filters on either side of the Hu Line led to divergent beta diversity patterns.Specifically,climate-driven species turnover and habitat heterogeneity-related species nestedness dominated the regions east and west of the line,respectively.Additionally,bird species with stronger dispersal ability were more susceptible to environmental filtering,resulting in more homogeneous assemblages.Our results indicated that regions with distinctive geographical backgrounds may present different ecological factors that lead to divergent assemblage dissimilarity patterns,and dispersal ability determines the response of assemblages to these ecological factors.Identifying a single universal explanation for the observed pattern without considering these aspects may lead to simplistic or incomplete conclusions.Consequently,a comprehensive understanding of large-scale beta diversity patterns and effective planning of conservation strategies necessitate the consideration of both geographical background and species dispersal ability.
文摘China has allocated a combined 10 trillion yuan(US$1.39 trillion)in new fiscal funding to replace hidden local government debt,or liabilities that local governments do not o"cially report.This marks one of the largest moves of its kind in recent years.The Standing Committee of the National People’s Congress(NPC),China’s top legislative body,approved a bill that raises the ceiling on local government debt by 6 trillion yuan(US$834 billion)to address existing hidden debt,Xu Hongcai,deputy head of the NPC’s Financial and Economic Affairs Committee,said at a press conference after the Standing Committee of the 14th NPC concluded its 12th session in Beijing on November 8.
基金Sponsored by Project of Teaching Reform Research of Education Department of Shandong Province in 2020“Innovation and Practice of Tourism Management Application-oriented Talent Training Mode under the Background of First-class Specialty Construction and International Certification”(M2020289).
文摘Engaging students in the examination of the local significance of newly established historic districts within real-life contexts serves as a crucial method for exploring the geographical practical ability.This study utilizes Dongyi Town in Rizhao City as a case study,employing text analysis,field research,and interviews.It draws upon the theoretical frameworks of place and placelessness,while integrating research resources from two distinct perspectives:the evolution of the landscape and the emotional attitudes of various subjects towards the neighborhood.Students will be encouraged to investigate the environmental characteristics of the natural geography inherent in Dongyi Town,the current state of urban development and its implications for the local economy,culture,and environment through field visits and firsthand experiences.By employing the theory of place and placelessness,students will gain a deeper understanding of the underlying subjects and values associated with the landscape.Furthermore,they will learn to utilize this theoretical framework to reflect on the significance of districts to individuals,thereby enhancing their geographical practical abilities.
基金Henan Province Higher Education Teaching Reform Research and Practice Project“Industry Guidance,Integration of Medical Education,and Professional Reality:Innovation and Practice of Medical Technology(1+2)Education Model”(2024SJGLX0725)Henan Province Medical Education Research Project“Research on the Innovation and Practice of Talent Training Model for Rehabilitation Therapy Technology Majors Based on Collaborative Education between Medicine and Education”(WJLX2023208)Zhengzhou Local College Teaching Reform Research and Practice Project“Research and Practice on the Talent Training Model of Rehabilitation Therapy Technology Based on the Integration of Industry and Education”(ZZJG-A1033)。
文摘This study empirically analyzes the application effect of the integration of medical and educational models in cultivating professional abilities in traditional Chinese medicine rehabilitation techniques.The research subjects are 100 students from the Traditional Chinese Medicine Rehabilitation Technology major at Y school.Through questionnaire scores,practical training results,and interview data,this study explores the outcomes of this integrated approach.The findings reveal that students in the experimental group significantly outperform those in the control group in terms of practical operation skills,professional responsibility,and communication and collaboration skills.This research confirms the notable role of the medical-educational integration model in enhancing the professional skills and accomplishments of students majoring in traditional Chinese medicine rehabilitation,providing a scientific basis for vocational education reform and the cultivation of rehabilitation technical talents.
