The crossover between short-range and long-range(LR)universal behaviors remains a central theme in the physics of LR interacting systems.The competition between LR coupling and the Berezinskii-Kosterlitz-Thouless mech...The crossover between short-range and long-range(LR)universal behaviors remains a central theme in the physics of LR interacting systems.The competition between LR coupling and the Berezinskii-Kosterlitz-Thouless mechanism makes the problem more subtle and less understood in the two-dimensional(2D)XY model,a cornerstone for investigating low-dimensional phenomena and their implications in quantum computation.We study the 2D XY model with algebraically decaying interaction~1/r^(2+σ).Utilizing an advanced update strategy,we conduct LR Monte Carlo simulations of the model up to a linear size of L=8192.Our results demonstrate continuous phase transitions into a ferromagnetic phase forσ<2,which exhibit the simultaneous emergence of a long-ranged order and a power-law decaying correlation function due to the Goldstone mode.Furthermore,we fnd logarithmic scaling behaviors in the low-temperature phase atσ=2.The observed scaling behaviors in the low-temperature phase forσ≤2 agree with our theoretical analysis.Our fndings request further theoretical understanding and can be of practical application in cutting-edge experiments like Rydberg atom arrays.展开更多
Moiré superlattices provide a new platform to engineer various many-body problems. In this work, we consider arrays of quantum dots(QD) realized on semiconductor moiré superlattices with a deep moiré po...Moiré superlattices provide a new platform to engineer various many-body problems. In this work, we consider arrays of quantum dots(QD) realized on semiconductor moiré superlattices with a deep moiré potential. We diagonalize single QD with multiple electrons, and find degenerate ground states serving as local degrees of freedom(qudits) in the superlattice. With a deep moiré potential, the hopping and exchange interaction between nearby QDs become irrelevant,and the direct Coulomb interaction of the density–density type dominates. Therefore, nearby QDs must arrange the spatial densities to optimize the Coulomb energy. When the local Hilbert space has a two-fold orbital degeneracy, we find that a square superlattice realizes an anisotropic XY model, while a triangular superlattice realizes a generalized XY model with geometric frustration.展开更多
46,XY性发育异常(disorders/differences of sex development,DSD)是一组核型为46,XY,染色体、性腺和表型不匹配的先天性疾病,约占所有DSD患者的50%[1-3]。该类疾病表型谱复杂,可从轻度男性化不全到完全女性表型,如尿道下裂、小阴茎、...46,XY性发育异常(disorders/differences of sex development,DSD)是一组核型为46,XY,染色体、性腺和表型不匹配的先天性疾病,约占所有DSD患者的50%[1-3]。该类疾病表型谱复杂,可从轻度男性化不全到完全女性表型,如尿道下裂、小阴茎、隐睾、女性化外生殖器、第二性征不发育等。DSD病因复杂,既包括外源性因素,如母体因素、化学制剂及环境干扰物等;又有内源性因素.展开更多
目的分析45,X/46,XY嵌合体患儿的临床资料,总结其临床特征并探讨其性腺及残留苗勒氏管组织的外科治疗方法。方法本研究为回顾性研究,以2011年3月至2023年7月就诊于湖南省儿童医院泌尿外科、核型为45,X/46,XY嵌合体患儿为研究对象,患儿...目的分析45,X/46,XY嵌合体患儿的临床资料,总结其临床特征并探讨其性腺及残留苗勒氏管组织的外科治疗方法。方法本研究为回顾性研究,以2011年3月至2023年7月就诊于湖南省儿童医院泌尿外科、核型为45,X/46,XY嵌合体患儿为研究对象,患儿均行人绒毛膜促性腺激素(human chorionic gonadotrophin,HCG)刺激试验、腹腔镜探查、膀胱镜探查及双侧性腺活检术;经过多学科联合会诊(multidisciplinary team,MDT),部分患儿行性腺切除及外阴整形手术。收集患儿临床、实验室检查结果以及随访特征等资料。结果本研究共纳入23例45,X/46,XY嵌合体患儿,初诊年龄为1岁4个月(10个月,11岁11个月)。8例患儿出生后社会性别为女性,且都保持女性性别抚养,外部男性化评分(external masculinization score,EMS)为1(0,3)分。15例出生后社会性别为男性,11例保持男性性别抚养,EMS为4.5(2.7,8.4)分;4例按中性性别抚养,EMS为3.7(3.0,8.6)分。性染色体结构异常(B=3.499,β=0.555,P=0.019)是生殖器异常的严重程度的影响因素,嵌合比例(B=-3.454,β=-0.297,P=0.189)和HCG刺激试验(B=0.162,β=0.051,P=0.800)均不是生殖器异常严重程度的影响因素。按性腺类型分类:完全性性腺发育不良3例,混合性性腺发育不良12例,部分性腺发育不良6例,双侧正常睾丸1例,卵睾型性发育异常(differences of sex development,DSD)1例。8例患儿选择维持女性性别抚养,其中3例接受了双侧性腺切除和生殖器整形手术。11例选择维持男性性别抚养的患儿,其中4例混合性性腺发育不良的患儿接受了单侧条纹性腺切除术,1例部分性腺发育不良的患儿接受了单侧发育不良睾丸切除术,1例卵睾型DSD患儿接受了右侧卵巢切除术。在随访期间,有2例患儿自发进入了青春期。13例患儿接受了生殖器整形手术,其中9例保留了子宫和阴道结构,未出现任何并发症。结论尿道下裂合并隐睾症和残留苗勒氏管结构是45,X/46,XY嵌合体患儿的常见表型,应在进行全面评估后谨慎选择性别,同时可考虑对部分患者进行生殖器整形手术。对于选择男性性别的儿童,可保留苗勒氏管结构。展开更多
女性性发育异常(disorders of sex development,DSD)患者表现出性染色体、性腺、外生殖器及第二性征等方面一项或多项的异常或不相符。其包含一大类疾病,分类较复杂,目前临床较为认可的是根据染色体核型分为3类:46,XX型DSD、46,XY型DSD...女性性发育异常(disorders of sex development,DSD)患者表现出性染色体、性腺、外生殖器及第二性征等方面一项或多项的异常或不相符。其包含一大类疾病,分类较复杂,目前临床较为认可的是根据染色体核型分为3类:46,XX型DSD、46,XY型DSD及染色体异常型DSD。本文报告1例染色体核型为45,X/46,XY嵌合体的混合性性腺发育不全,同时合并性腺恶变的18岁患者,通过整理相关文献资料,以期为该类疾病的诊断、治疗及预后等提供临床经验。展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.12204173 and 12275263)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0301900)supported by the Natural Science Foundation of Fujian Province 802 of China(Grant No.2023J02032)。
文摘The crossover between short-range and long-range(LR)universal behaviors remains a central theme in the physics of LR interacting systems.The competition between LR coupling and the Berezinskii-Kosterlitz-Thouless mechanism makes the problem more subtle and less understood in the two-dimensional(2D)XY model,a cornerstone for investigating low-dimensional phenomena and their implications in quantum computation.We study the 2D XY model with algebraically decaying interaction~1/r^(2+σ).Utilizing an advanced update strategy,we conduct LR Monte Carlo simulations of the model up to a linear size of L=8192.Our results demonstrate continuous phase transitions into a ferromagnetic phase forσ<2,which exhibit the simultaneous emergence of a long-ranged order and a power-law decaying correlation function due to the Goldstone mode.Furthermore,we fnd logarithmic scaling behaviors in the low-temperature phase atσ=2.The observed scaling behaviors in the low-temperature phase forσ≤2 agree with our theoretical analysis.Our fndings request further theoretical understanding and can be of practical application in cutting-edge experiments like Rydberg atom arrays.
基金Project supported by the National Natural Science Foundation of China (Grant No. 12274005)the National Key Research and Development Program of China (Grant No. 2021YFA1401903)Innovation Program for Quantum Science and Technology (Grant No. 2021ZD0302403)。
文摘Moiré superlattices provide a new platform to engineer various many-body problems. In this work, we consider arrays of quantum dots(QD) realized on semiconductor moiré superlattices with a deep moiré potential. We diagonalize single QD with multiple electrons, and find degenerate ground states serving as local degrees of freedom(qudits) in the superlattice. With a deep moiré potential, the hopping and exchange interaction between nearby QDs become irrelevant,and the direct Coulomb interaction of the density–density type dominates. Therefore, nearby QDs must arrange the spatial densities to optimize the Coulomb energy. When the local Hilbert space has a two-fold orbital degeneracy, we find that a square superlattice realizes an anisotropic XY model, while a triangular superlattice realizes a generalized XY model with geometric frustration.
文摘46,XY性发育异常(disorders/differences of sex development,DSD)是一组核型为46,XY,染色体、性腺和表型不匹配的先天性疾病,约占所有DSD患者的50%[1-3]。该类疾病表型谱复杂,可从轻度男性化不全到完全女性表型,如尿道下裂、小阴茎、隐睾、女性化外生殖器、第二性征不发育等。DSD病因复杂,既包括外源性因素,如母体因素、化学制剂及环境干扰物等;又有内源性因素.
文摘目的分析45,X/46,XY嵌合体患儿的临床资料,总结其临床特征并探讨其性腺及残留苗勒氏管组织的外科治疗方法。方法本研究为回顾性研究,以2011年3月至2023年7月就诊于湖南省儿童医院泌尿外科、核型为45,X/46,XY嵌合体患儿为研究对象,患儿均行人绒毛膜促性腺激素(human chorionic gonadotrophin,HCG)刺激试验、腹腔镜探查、膀胱镜探查及双侧性腺活检术;经过多学科联合会诊(multidisciplinary team,MDT),部分患儿行性腺切除及外阴整形手术。收集患儿临床、实验室检查结果以及随访特征等资料。结果本研究共纳入23例45,X/46,XY嵌合体患儿,初诊年龄为1岁4个月(10个月,11岁11个月)。8例患儿出生后社会性别为女性,且都保持女性性别抚养,外部男性化评分(external masculinization score,EMS)为1(0,3)分。15例出生后社会性别为男性,11例保持男性性别抚养,EMS为4.5(2.7,8.4)分;4例按中性性别抚养,EMS为3.7(3.0,8.6)分。性染色体结构异常(B=3.499,β=0.555,P=0.019)是生殖器异常的严重程度的影响因素,嵌合比例(B=-3.454,β=-0.297,P=0.189)和HCG刺激试验(B=0.162,β=0.051,P=0.800)均不是生殖器异常严重程度的影响因素。按性腺类型分类:完全性性腺发育不良3例,混合性性腺发育不良12例,部分性腺发育不良6例,双侧正常睾丸1例,卵睾型性发育异常(differences of sex development,DSD)1例。8例患儿选择维持女性性别抚养,其中3例接受了双侧性腺切除和生殖器整形手术。11例选择维持男性性别抚养的患儿,其中4例混合性性腺发育不良的患儿接受了单侧条纹性腺切除术,1例部分性腺发育不良的患儿接受了单侧发育不良睾丸切除术,1例卵睾型DSD患儿接受了右侧卵巢切除术。在随访期间,有2例患儿自发进入了青春期。13例患儿接受了生殖器整形手术,其中9例保留了子宫和阴道结构,未出现任何并发症。结论尿道下裂合并隐睾症和残留苗勒氏管结构是45,X/46,XY嵌合体患儿的常见表型,应在进行全面评估后谨慎选择性别,同时可考虑对部分患者进行生殖器整形手术。对于选择男性性别的儿童,可保留苗勒氏管结构。
文摘女性性发育异常(disorders of sex development,DSD)患者表现出性染色体、性腺、外生殖器及第二性征等方面一项或多项的异常或不相符。其包含一大类疾病,分类较复杂,目前临床较为认可的是根据染色体核型分为3类:46,XX型DSD、46,XY型DSD及染色体异常型DSD。本文报告1例染色体核型为45,X/46,XY嵌合体的混合性性腺发育不全,同时合并性腺恶变的18岁患者,通过整理相关文献资料,以期为该类疾病的诊断、治疗及预后等提供临床经验。
