Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarctio...Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarction, and assessed outcomes according to the U.S. National Institutes of Health Stroke Score, Modified Rankin Scale, and transcranial magnetic stimulation motor-evoked potential. Compared with the control group, the clinical total effective rate and the cortical potential rise rate of the upper limbs were significantly higher, the central motor conduction time of upper limb was significantly shorter, and the upper limb motor-evoked potential amplitude was significantly increased, in the ozone group. In the ozone group, the National Institutes of Health Stroke Score was positively correlated with the central motor conduction time and the motor-evoked potential amplitude of the upper limb. Central motor conduction time and motor-evoked potential amplitude of the upper limb may be effective indicators of motor-evoked potentials to assess upper limb motor function in cerebral infarct patients. Furthermore, major ozonated autohemotherapy may promote motor function recovery of the upper limb in patients with acute cerebral infarction.展开更多
Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in...Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in patients with stroke.Methods:Twelve patients with stroke were recruited to participate in the intervention of 3 weeks.At the baseline and post intervention,two times of evaluation including Fugl-Meyer upper-extremity scale(FMS-UE),transcranial magnetic stimulation(TMS)measurement and motion evaluation were performed.Results:No significant difference was observed between two groups at baseline evaluation.After the intervention,the FMS-UE scores presented a greater improvement in the VR group compared with the control group.TMS measurement showed that there was significant difference in cortex latency and central motor conduction time between two groups after the intervention,but no significant difference in the amplitude of motor event potential was observed.In addition,there was a significant correlation between game scores and FMS-UE scores.Conclusions:The novel glasses-free VR training was at least as effective as conventional occupational therapy in upper limb motor function,improving nerve conduction time and corticospinal excitability in patient with stroke.展开更多
Objective: to analyze the effect of acupuncture combined with rehabilitation technology on upper limb motor dysfunction in the clinical treatment of stroke. Methods: a total of 80 stroke patients admitted to our hospi...Objective: to analyze the effect of acupuncture combined with rehabilitation technology on upper limb motor dysfunction in the clinical treatment of stroke. Methods: a total of 80 stroke patients admitted to our hospital from January 2018 to January 2019 were randomly divided into two groups by odd-even serial number, with 40 patients in the observation group and 40 in the control group. The control group was treated with rehabilitation technology, and the observation group was treated with acupuncture combined with rehabilitation training. After the treatment, the treatment effect of the observation group and the control group was compared, and the scores of daily living ability and limb motor function of the two groups were statistically compared and analyzed. Results: according to data analysis, there were 35 patients in the observation group with significant therapeutic effect (87.5%) and 28 patients in the control group with significant therapeutic effect (70.00%). Comparison of two groups of treatment effect, the observation group was better (P < 0.05). After treatment, the scores of daily living ability and upper limb motor function in observation group were better than those in control group (P < 0.05). Conclusion: according to the experimental results, the motor dysfunction of stroke patients has been significantly improved after acupuncture combined with rehabilitation technology treatment, and the patients' daily living ability and upper limb movement ability have been significantly improved, and the efficacy is accurate, which can be widely promoted in clinical practice.展开更多
Objective:To observe the impacts of the combined treatment of Tongdu Tiaoshen moxibustion(moxibustion for promoting the circulation of the governor vessel and regulating the spirit)and rehabilitation training on the m...Objective:To observe the impacts of the combined treatment of Tongdu Tiaoshen moxibustion(moxibustion for promoting the circulation of the governor vessel and regulating the spirit)and rehabilitation training on the motor function recovery in the patients with apoplectic hemiplegia.Methods:A total of 50 patients with apoplectic hemiplegia and qualified in the trial recruitment criteria were divided into two groups according to random number table,25 cases in each group.In the control group,the simple rehabilitation training was provided.In the observation group,on the base of the treatment as the control group,Tongdu Tiaoshen moxibustion was given.Main acupoints:Baihul(百会GV20),Fengfu(风府GV16)and Dazhui(大椎GV14).The treatment was given once a day,6 treatments a week,4 weeks as one course and two courses of treatment were required.Before and after treatment,the scores of Fugle-Meyer assessment(FMA),the modified Barthel index(MBI)and action research arm test(ARAT)were detected before and after treatment in the two groups separately.Results:After 4 and 8 weeks of treatment,the scores of FMA,MBI and ARAT were all improved obviously as compared with those before treatment respectively in patients of the two groups(all P<0.01).After8 weeks of treatment,the score of each scale in the observation group was more obviously improved as compared with the control group(all P<0.05).The difference in the clinical therapeutic effect was significant statistically between the two groups(P=0.005).Conclusion:The combined treatment of Tongdu Tiaoshen moxibustion and rehabilitation training promotes the recovery of the upper limb motor function and improves the self-ability of living activities in the patients with apoplectic hemiplegia.The long-term effect of this combined therapy is superior to that of simple rehabilitation training.展开更多
BACKGROUND:Botulinum toxin type A(BTX-A)is mostly to be used to treat various diseases of motor disorders,whereas its effect on muscle spasm after stroke and brain injury needs further observation.OBJECTIVE:To observe...BACKGROUND:Botulinum toxin type A(BTX-A)is mostly to be used to treat various diseases of motor disorders,whereas its effect on muscle spasm after stroke and brain injury needs further observation.OBJECTIVE:To observe the effect of BTX-A plus rehabilitative training on treating muscle spasm after stroke and brain injury.DESIGN:A randomized controlled observation.SETTINGS:Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University.PARTICIPANTS:Sixty inpatients with brain injury and stroke were selected from the Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University from January 2001 to August 2006.They were all confirmed by CT and MRI,and had obvious increase of spastic muscle strength in upper limbs,their Ashworth grades were grade 2 or above.The patients were randomly divided into treatment group(n=30)and control group(n=30).METHODS:①Patients in the treatment group undertook comprehensive rehabilitative trainings,and they were administrated with domestic BTX-A,which was provided by Lanzhou Institute of Biological Products,Ministry of Health(S10970037),and the muscles of flexion spasm were selected for upper limbs,20-25 IU for each site.②Patients in the treatment group were assessed before injection and at 1 and 2 weeks,1 and 3 months after injection respectively,and those in the control group were assessed at corresponding time points.The recovery of muscle spasm was assessed by modified Ashworth scale(MAS,grade 0-Ⅳ;Grade 0 for without increase of muscle strength;GradeⅣfor rigidity at passive flexion and extension);The recovery of motor function of the upper limbs was evaluated with Fugl-Meyer Assessment(FMA,total score was 226 points,including 100 for exercise,14 for balance,24 for sense,44 for joint motion,44 for pain and 66 for upper limb);The ADL were evaluated with Barthel index,the total score was 100 points,60 for mild dysfunction,60-41 for moderate dysfunction,<40 for severe dysfunction).MAIN OUTCOME MEASURES:Changes of MAS grade,FMA scores and Barthel index before and after BTX-A injection.RESULTS:All the 60 patients with brain injury and stroke were involved in the analysis of results.①FMA scores of upper limbs:The FMA score in the treatment group at 2 weeks after treatment was higher than that before treatment[(14.98±10.14),(13.10±9.28)points,P<0.05],whereas there was no significant difference at corresponding time point in the control group.The FMA scores at 1 and 3 months in the treatment group[(23.36±10.69),(35.36±11.36)points]were higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].②MAS grades of upper limbs:There were obviously fewer cases of gradeⅢin MAS at 2 weeks after treatment than before treatment in the treatment group(0,9 cases,P<0.05),whereas there was no obvious difference in the control group.There were obviously fewer cases of gradeⅢin MAS at 2 weeks and 1 month after treatment in the treatment group(0,0 case)than the control group(5,2 cases,P<0.01).③Barthel index of upper limbs:The Barthel index at 2 weeks after treatment was higher than that before treatment in the treatment group[(30.36±22.25),(28.22±26.21)points,P<0.05],whereas there was no significant difference in the control group.The Barthel indexes at 1 and 3 months after treatment in the treatment group were obviously higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].CONCLUSION:BTX-A has obvious efficacy on decreasing muscle tension after stroke and brain injury,and relieving muscle spasm;Meanwhile,the combination with rehabilitative training can effectively ameliorate the motor function of upper limbs and ADL of the patients.展开更多
Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with isc...Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with ischemic stroke were divided into the treatment group and the control group(n=38 in each). Based on the Brunnstrom's stage of Xingnao Kaiqiao acupuncture combined with rehabilitation training was used in the treatment group, and the control group was given rehabilitation training. FuglMeyer Assessment of the upper extremity(FMA-UE), Action Research Arm Test(ARAT) and Simple Test for Evaluating hand Function(STEF) were adopted separately to compare scores before treatment and 8 weeks after treatment. Results: The difference was not statistically significant in the two groups of patients for comparison of FMA-UE, ARAT and STEF scores before treatment(P>0.05). The difference was statistically significant in the two groups of score comparison of FMA-UE, ARAT and STEF after treatment(P<0.05). Conclusion: The Xingnao Kaiqiao acupuncture has its unique advantages in improving recovery of motor function of upper limb and hand in recovery period after stroke.展开更多
目的探究脑卒中患者应用虚拟现实(VR)技术结合运动训练对上肢运动功能(ULMF)康复的疗效及神经机制。方法选取2023年1月~2025年6月内,收治于我院的60例脑卒中患者,按干预方案分组,分为A组(30例,基础康复训练)和B组(30例,VR技术结合运动训...目的探究脑卒中患者应用虚拟现实(VR)技术结合运动训练对上肢运动功能(ULMF)康复的疗效及神经机制。方法选取2023年1月~2025年6月内,收治于我院的60例脑卒中患者,按干预方案分组,分为A组(30例,基础康复训练)和B组(30例,VR技术结合运动训练)。对照Box and Block测试(BBT)、Fugl-Meyer上肢部分(FMA-UE)、改良Barthel指数(MBI)等评分变化,利用功能磁共振成像(fMRI)评估ULMF、日常生活活动能力(ADL)及脑功能区激活变化。结果干预后A、B组的BBT、FMA-UE及MBI评分均高于干预前,且B组均高于A组(P<0.05)。fMRI显示B组患侧顶叶皮层、前运动皮层等区域激活明显增强,且激活强度与ULMF改善呈正相关(P<0.05)。结论脑卒中患者应用VR技术结合运动训练的疗效确切,可促进ULMF更快康复,也可提升其ADL水平,其神经机制可能与促进神经可塑性增强、镜像神经元系统激活及大脑皮层重组等有关。展开更多
背景:近年来随着脑机接口技术的发展,它在脑卒中康复过程中的疗效已得到证实,并取得了丰富成果,亟需进行可视化分析以了解研究前沿与热点。目的:应用文献计量学可视化软件分析脑机接口在脑卒中康复领域应用的前沿热点及研究趋势。方法:...背景:近年来随着脑机接口技术的发展,它在脑卒中康复过程中的疗效已得到证实,并取得了丰富成果,亟需进行可视化分析以了解研究前沿与热点。目的:应用文献计量学可视化软件分析脑机接口在脑卒中康复领域应用的前沿热点及研究趋势。方法:以Web of Science核心合集与中国知网数据库作为研究基础,利用Citespace 6.4.1、VOSviewer 1.6.20和Excel 2021工具对检索所得的与脑机接口技术在脑卒中功能恢复中应用相关的中英文相关文献进行可视化数据分析,通过科学计量手段深入剖析脑机接口技术在脑卒中康复领域的研究现状、热点议题及未来趋势。结果与结论:①共纳入2003-2025年中英文文献985篇(英文879篇,中文106篇),该领域国内外年发文量均持续增长;②中国、美国与德国是该领域年发文量最多的国家;该领域最具影响力的机构为德国图宾根大学,中文发文量最高的机构为复旦大学附属华山医院;瑞士的《FRONTIERS IN NEUROSCIENCE》是英文发文量最高的期刊,《中国康复医学杂志》为中文发文量最高的期刊;英文发文量最高的作者为德国的Birbaumer Niels,中文发文量最高的作者为贾杰;③文献分析可见,国际研究侧重理论与临床效果的验证,且关注上肢功能与神经的恢复;国内研究更关注技术与系统的优化与开发,侧重康复领域应用的广泛探索;④运动想象为中英文文献共同的高频关键词,研究热点聚焦在基于脑电图、运动想象的脑机接口系统开发;⑤多模态结合、人工智能融合、康复手段拓展及国际合作深化可能是该领域未来发展的主要趋势。展开更多
目的了解运动想象(MI)疗法在脑卒中后上肢功能康复中的研究现状,分析该领域的研究热点,探究未来发展趋势。方法在Web of Sciencee核心集中检索建库至2025年1月29日发表的相关文献,运用CiteSpace软件对纳入的文献进行可视化分析。结果共...目的了解运动想象(MI)疗法在脑卒中后上肢功能康复中的研究现状,分析该领域的研究热点,探究未来发展趋势。方法在Web of Sciencee核心集中检索建库至2025年1月29日发表的相关文献,运用CiteSpace软件对纳入的文献进行可视化分析。结果共纳入136篇文献,2004—2025年,发文量整体呈现波动增长趋势(R2=0.3723),MI疗法在脑卒中后上肢功能康复的相关研究集中在中国(24篇)、日本(15篇)、美国(14篇)和德国(11篇);对机构进行分析,复旦大学(6篇)、上海交通大学(5篇)、图宾根大学(5篇)发文量较多,处于核心地位;发文量前3位的作者是GUAN(4篇)、CUNTAI(4篇)、ANG(4篇);关键词分析结果显示,该领域的研究热点主要集中在脑机接口、分级运动想象、运动诱发电位、经颅磁刺激等。结论MI疗法在脑卒中后上肢功能康复领域的研究波动上升,国内外学者与研究机构应增进学术交流与合作,共同促进该领域的持续发展。展开更多
In this study, stroke patients received constraint-induced movement therapy for 3 weeks. Before and after constraint-induced movement therapy, the flexibility of their upper limbs on the affected side was assessed usi...In this study, stroke patients received constraint-induced movement therapy for 3 weeks. Before and after constraint-induced movement therapy, the flexibility of their upper limbs on the affected side was assessed using the Wolf motor function test, and daily use of their affected limbs was assessed using the movement activities log, and cerebral functional reorganization was assessed by functional magnetic resonance imaging. The Wolf motor function test score and the movement activities log quantity and quality scores were significantly increased, while action performance time in the Wolf motor function test was significantly decreased after constraint-induced movement therapy. By functional magnetic resonance imaging examination, only scattered activation points were visible on the affected side before therapy. In contrast, the volume of the activated area was increased after therapy. The activation volume in the sensorimotor area was significantly different before and after therapy, and the activation area increased and appeared adjusted. In addition to the activated area around the lesions being decreased, there were also some new activated areas, including the supplementary movement area, premotor area and the ipsilateral sensorimotor area. Our findings indicate that constraint-induced movement therapy significantly improves the movement ability and daily use of the affected upper limbs in stroke patients and promotes cerebral functional reorganization.展开更多
基金supported by the Guangdong Province Medical Science Research Fund, No. B200258
文摘Major ozonated autohemotherapy is classically used in treating ischemic disorder of the lower limbs In the present study, we performed major ozonated autohemotherapy treatment in patients with acute cerebral infarction, and assessed outcomes according to the U.S. National Institutes of Health Stroke Score, Modified Rankin Scale, and transcranial magnetic stimulation motor-evoked potential. Compared with the control group, the clinical total effective rate and the cortical potential rise rate of the upper limbs were significantly higher, the central motor conduction time of upper limb was significantly shorter, and the upper limb motor-evoked potential amplitude was significantly increased, in the ozone group. In the ozone group, the National Institutes of Health Stroke Score was positively correlated with the central motor conduction time and the motor-evoked potential amplitude of the upper limb. Central motor conduction time and motor-evoked potential amplitude of the upper limb may be effective indicators of motor-evoked potentials to assess upper limb motor function in cerebral infarct patients. Furthermore, major ozonated autohemotherapy may promote motor function recovery of the upper limb in patients with acute cerebral infarction.
基金This study was supported by National Natural Science Foundation of China(Nos.31771016,32071316,and 81971224)partly supported by Guangdong Basic and Applied Basic Research Foundation(No.2020A1515011356)+1 种基金Guangzhou Research Collaborative Innovation Projects(No.201907010034)the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.2020-JKCS005).
文摘Background:Virtual reality(VR)technology is increasingly used in stroke rehabilitation.This study aimed to investigate the effectiveness of using the glasses-free VR training to improve motor function of upper limb in patients with stroke.Methods:Twelve patients with stroke were recruited to participate in the intervention of 3 weeks.At the baseline and post intervention,two times of evaluation including Fugl-Meyer upper-extremity scale(FMS-UE),transcranial magnetic stimulation(TMS)measurement and motion evaluation were performed.Results:No significant difference was observed between two groups at baseline evaluation.After the intervention,the FMS-UE scores presented a greater improvement in the VR group compared with the control group.TMS measurement showed that there was significant difference in cortex latency and central motor conduction time between two groups after the intervention,but no significant difference in the amplitude of motor event potential was observed.In addition,there was a significant correlation between game scores and FMS-UE scores.Conclusions:The novel glasses-free VR training was at least as effective as conventional occupational therapy in upper limb motor function,improving nerve conduction time and corticospinal excitability in patient with stroke.
文摘Objective: to analyze the effect of acupuncture combined with rehabilitation technology on upper limb motor dysfunction in the clinical treatment of stroke. Methods: a total of 80 stroke patients admitted to our hospital from January 2018 to January 2019 were randomly divided into two groups by odd-even serial number, with 40 patients in the observation group and 40 in the control group. The control group was treated with rehabilitation technology, and the observation group was treated with acupuncture combined with rehabilitation training. After the treatment, the treatment effect of the observation group and the control group was compared, and the scores of daily living ability and limb motor function of the two groups were statistically compared and analyzed. Results: according to data analysis, there were 35 patients in the observation group with significant therapeutic effect (87.5%) and 28 patients in the control group with significant therapeutic effect (70.00%). Comparison of two groups of treatment effect, the observation group was better (P < 0.05). After treatment, the scores of daily living ability and upper limb motor function in observation group were better than those in control group (P < 0.05). Conclusion: according to the experimental results, the motor dysfunction of stroke patients has been significantly improved after acupuncture combined with rehabilitation technology treatment, and the patients' daily living ability and upper limb movement ability have been significantly improved, and the efficacy is accurate, which can be widely promoted in clinical practice.
基金Supported by Research Program of Anhui University of Traditional Chinese Medicine:2019zryb21。
文摘Objective:To observe the impacts of the combined treatment of Tongdu Tiaoshen moxibustion(moxibustion for promoting the circulation of the governor vessel and regulating the spirit)and rehabilitation training on the motor function recovery in the patients with apoplectic hemiplegia.Methods:A total of 50 patients with apoplectic hemiplegia and qualified in the trial recruitment criteria were divided into two groups according to random number table,25 cases in each group.In the control group,the simple rehabilitation training was provided.In the observation group,on the base of the treatment as the control group,Tongdu Tiaoshen moxibustion was given.Main acupoints:Baihul(百会GV20),Fengfu(风府GV16)and Dazhui(大椎GV14).The treatment was given once a day,6 treatments a week,4 weeks as one course and two courses of treatment were required.Before and after treatment,the scores of Fugle-Meyer assessment(FMA),the modified Barthel index(MBI)and action research arm test(ARAT)were detected before and after treatment in the two groups separately.Results:After 4 and 8 weeks of treatment,the scores of FMA,MBI and ARAT were all improved obviously as compared with those before treatment respectively in patients of the two groups(all P<0.01).After8 weeks of treatment,the score of each scale in the observation group was more obviously improved as compared with the control group(all P<0.05).The difference in the clinical therapeutic effect was significant statistically between the two groups(P=0.005).Conclusion:The combined treatment of Tongdu Tiaoshen moxibustion and rehabilitation training promotes the recovery of the upper limb motor function and improves the self-ability of living activities in the patients with apoplectic hemiplegia.The long-term effect of this combined therapy is superior to that of simple rehabilitation training.
基金a grant from the Tackle Key Problem and Planning Projectin Science and Technology of Hebei Province,No.052761224
文摘BACKGROUND:Botulinum toxin type A(BTX-A)is mostly to be used to treat various diseases of motor disorders,whereas its effect on muscle spasm after stroke and brain injury needs further observation.OBJECTIVE:To observe the effect of BTX-A plus rehabilitative training on treating muscle spasm after stroke and brain injury.DESIGN:A randomized controlled observation.SETTINGS:Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University.PARTICIPANTS:Sixty inpatients with brain injury and stroke were selected from the Department of Rehabilitation,Department of Neurology and Department of Neurosurgery,the Second Hospital of Hebei Medical University from January 2001 to August 2006.They were all confirmed by CT and MRI,and had obvious increase of spastic muscle strength in upper limbs,their Ashworth grades were grade 2 or above.The patients were randomly divided into treatment group(n=30)and control group(n=30).METHODS:①Patients in the treatment group undertook comprehensive rehabilitative trainings,and they were administrated with domestic BTX-A,which was provided by Lanzhou Institute of Biological Products,Ministry of Health(S10970037),and the muscles of flexion spasm were selected for upper limbs,20-25 IU for each site.②Patients in the treatment group were assessed before injection and at 1 and 2 weeks,1 and 3 months after injection respectively,and those in the control group were assessed at corresponding time points.The recovery of muscle spasm was assessed by modified Ashworth scale(MAS,grade 0-Ⅳ;Grade 0 for without increase of muscle strength;GradeⅣfor rigidity at passive flexion and extension);The recovery of motor function of the upper limbs was evaluated with Fugl-Meyer Assessment(FMA,total score was 226 points,including 100 for exercise,14 for balance,24 for sense,44 for joint motion,44 for pain and 66 for upper limb);The ADL were evaluated with Barthel index,the total score was 100 points,60 for mild dysfunction,60-41 for moderate dysfunction,<40 for severe dysfunction).MAIN OUTCOME MEASURES:Changes of MAS grade,FMA scores and Barthel index before and after BTX-A injection.RESULTS:All the 60 patients with brain injury and stroke were involved in the analysis of results.①FMA scores of upper limbs:The FMA score in the treatment group at 2 weeks after treatment was higher than that before treatment[(14.98±10.14),(13.10±9.28)points,P<0.05],whereas there was no significant difference at corresponding time point in the control group.The FMA scores at 1 and 3 months in the treatment group[(23.36±10.69),(35.36±11.36)points]were higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].②MAS grades of upper limbs:There were obviously fewer cases of gradeⅢin MAS at 2 weeks after treatment than before treatment in the treatment group(0,9 cases,P<0.05),whereas there was no obvious difference in the control group.There were obviously fewer cases of gradeⅢin MAS at 2 weeks and 1 month after treatment in the treatment group(0,0 case)than the control group(5,2 cases,P<0.01).③Barthel index of upper limbs:The Barthel index at 2 weeks after treatment was higher than that before treatment in the treatment group[(30.36±22.25),(28.22±26.21)points,P<0.05],whereas there was no significant difference in the control group.The Barthel indexes at 1 and 3 months after treatment in the treatment group were obviously higher than those in the control group[(20.55±10.22),(30.33±10.96)points,P<0.01].CONCLUSION:BTX-A has obvious efficacy on decreasing muscle tension after stroke and brain injury,and relieving muscle spasm;Meanwhile,the combination with rehabilitative training can effectively ameliorate the motor function of upper limbs and ADL of the patients.
基金Shandong Province Traditional Chinese Medicine Technology Development Program。
文摘Objective: To observe the effects of Xingnao Kaiqiao acupuncture(醒脑开窍针) on the motor function of upper limb and hand in the recovery period after stroke. Methods: Seventy-six cases of hemiplegia patients with ischemic stroke were divided into the treatment group and the control group(n=38 in each). Based on the Brunnstrom's stage of Xingnao Kaiqiao acupuncture combined with rehabilitation training was used in the treatment group, and the control group was given rehabilitation training. FuglMeyer Assessment of the upper extremity(FMA-UE), Action Research Arm Test(ARAT) and Simple Test for Evaluating hand Function(STEF) were adopted separately to compare scores before treatment and 8 weeks after treatment. Results: The difference was not statistically significant in the two groups of patients for comparison of FMA-UE, ARAT and STEF scores before treatment(P>0.05). The difference was statistically significant in the two groups of score comparison of FMA-UE, ARAT and STEF after treatment(P<0.05). Conclusion: The Xingnao Kaiqiao acupuncture has its unique advantages in improving recovery of motor function of upper limb and hand in recovery period after stroke.
文摘目的探究脑卒中患者应用虚拟现实(VR)技术结合运动训练对上肢运动功能(ULMF)康复的疗效及神经机制。方法选取2023年1月~2025年6月内,收治于我院的60例脑卒中患者,按干预方案分组,分为A组(30例,基础康复训练)和B组(30例,VR技术结合运动训练)。对照Box and Block测试(BBT)、Fugl-Meyer上肢部分(FMA-UE)、改良Barthel指数(MBI)等评分变化,利用功能磁共振成像(fMRI)评估ULMF、日常生活活动能力(ADL)及脑功能区激活变化。结果干预后A、B组的BBT、FMA-UE及MBI评分均高于干预前,且B组均高于A组(P<0.05)。fMRI显示B组患侧顶叶皮层、前运动皮层等区域激活明显增强,且激活强度与ULMF改善呈正相关(P<0.05)。结论脑卒中患者应用VR技术结合运动训练的疗效确切,可促进ULMF更快康复,也可提升其ADL水平,其神经机制可能与促进神经可塑性增强、镜像神经元系统激活及大脑皮层重组等有关。
文摘背景:近年来随着脑机接口技术的发展,它在脑卒中康复过程中的疗效已得到证实,并取得了丰富成果,亟需进行可视化分析以了解研究前沿与热点。目的:应用文献计量学可视化软件分析脑机接口在脑卒中康复领域应用的前沿热点及研究趋势。方法:以Web of Science核心合集与中国知网数据库作为研究基础,利用Citespace 6.4.1、VOSviewer 1.6.20和Excel 2021工具对检索所得的与脑机接口技术在脑卒中功能恢复中应用相关的中英文相关文献进行可视化数据分析,通过科学计量手段深入剖析脑机接口技术在脑卒中康复领域的研究现状、热点议题及未来趋势。结果与结论:①共纳入2003-2025年中英文文献985篇(英文879篇,中文106篇),该领域国内外年发文量均持续增长;②中国、美国与德国是该领域年发文量最多的国家;该领域最具影响力的机构为德国图宾根大学,中文发文量最高的机构为复旦大学附属华山医院;瑞士的《FRONTIERS IN NEUROSCIENCE》是英文发文量最高的期刊,《中国康复医学杂志》为中文发文量最高的期刊;英文发文量最高的作者为德国的Birbaumer Niels,中文发文量最高的作者为贾杰;③文献分析可见,国际研究侧重理论与临床效果的验证,且关注上肢功能与神经的恢复;国内研究更关注技术与系统的优化与开发,侧重康复领域应用的广泛探索;④运动想象为中英文文献共同的高频关键词,研究热点聚焦在基于脑电图、运动想象的脑机接口系统开发;⑤多模态结合、人工智能融合、康复手段拓展及国际合作深化可能是该领域未来发展的主要趋势。
文摘目的了解运动想象(MI)疗法在脑卒中后上肢功能康复中的研究现状,分析该领域的研究热点,探究未来发展趋势。方法在Web of Sciencee核心集中检索建库至2025年1月29日发表的相关文献,运用CiteSpace软件对纳入的文献进行可视化分析。结果共纳入136篇文献,2004—2025年,发文量整体呈现波动增长趋势(R2=0.3723),MI疗法在脑卒中后上肢功能康复的相关研究集中在中国(24篇)、日本(15篇)、美国(14篇)和德国(11篇);对机构进行分析,复旦大学(6篇)、上海交通大学(5篇)、图宾根大学(5篇)发文量较多,处于核心地位;发文量前3位的作者是GUAN(4篇)、CUNTAI(4篇)、ANG(4篇);关键词分析结果显示,该领域的研究热点主要集中在脑机接口、分级运动想象、运动诱发电位、经颅磁刺激等。结论MI疗法在脑卒中后上肢功能康复领域的研究波动上升,国内外学者与研究机构应增进学术交流与合作,共同促进该领域的持续发展。
基金funded by Capital Medical Development Foundation, No. 2009-2098
文摘In this study, stroke patients received constraint-induced movement therapy for 3 weeks. Before and after constraint-induced movement therapy, the flexibility of their upper limbs on the affected side was assessed using the Wolf motor function test, and daily use of their affected limbs was assessed using the movement activities log, and cerebral functional reorganization was assessed by functional magnetic resonance imaging. The Wolf motor function test score and the movement activities log quantity and quality scores were significantly increased, while action performance time in the Wolf motor function test was significantly decreased after constraint-induced movement therapy. By functional magnetic resonance imaging examination, only scattered activation points were visible on the affected side before therapy. In contrast, the volume of the activated area was increased after therapy. The activation volume in the sensorimotor area was significantly different before and after therapy, and the activation area increased and appeared adjusted. In addition to the activated area around the lesions being decreased, there were also some new activated areas, including the supplementary movement area, premotor area and the ipsilateral sensorimotor area. Our findings indicate that constraint-induced movement therapy significantly improves the movement ability and daily use of the affected upper limbs in stroke patients and promotes cerebral functional reorganization.
