1 Introduction As already known, complex prescription has been the outstanding feature of traditional Chinese medicine（TCM）. This fact therefore brings complicated formula with multicomponents from multimaterals, wh...1 Introduction As already known, complex prescription has been the outstanding feature of traditional Chinese medicine（TCM）. This fact therefore brings complicated formula with multicomponents from multimaterals, which produces some difficulties to detect the components and to control the quality. Shuanghuanglian preparations（SHLs）, including oral liquid, injection powder, capsule, and tablet, belong to a family of refined traditional Chinese patent medicine and a combined herbal remedy comprised of three herbs：展开更多
目的 分析金雀花乙醇提取物的化学成分。方法 采用超高效液相色谱-四极杆-飞行时间串联质谱(Ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry, UPLC-Q-TOF-MS/MS)技术,使用A...目的 分析金雀花乙醇提取物的化学成分。方法 采用超高效液相色谱-四极杆-飞行时间串联质谱(Ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry, UPLC-Q-TOF-MS/MS)技术,使用ACQUITY UPLC BEH C18色谱柱,流动相为0.1%甲酸水溶液和乙腈,线性梯度洗脱;采用电喷雾离子源在m/z50~1 500范围内采集数据;采用UNIFI V 1.9.2软件对数据进行预处理、峰检测、分子式推测,通过高分辨质谱数据结合数据库、文献和对照品进行对比,分析金雀花乙醇提取物中的化学成分。结果 共分析出47种化学成分,包括27种黄酮类、13种皂苷类、7种其他类成分,其中包括山奈酚-3-O-芸香糖苷、牡荆素、金丝桃苷、山奈苷、水仙苷、芹菜素、槲皮素、金合欢素等成分。结论 本研究分析了金雀花乙醇提取物中的化学成分,为后续金雀花的开发与利用提供了理论基础。展开更多
基金Supported by the National S&T Supporting Project in the 11th Five-Year Period(No.2006BAI08B04-01).
文摘1 Introduction As already known, complex prescription has been the outstanding feature of traditional Chinese medicine（TCM）. This fact therefore brings complicated formula with multicomponents from multimaterals, which produces some difficulties to detect the components and to control the quality. Shuanghuanglian preparations（SHLs）, including oral liquid, injection powder, capsule, and tablet, belong to a family of refined traditional Chinese patent medicine and a combined herbal remedy comprised of three herbs：
