目的:探讨基于诺丁斯关怀教育理论的亲情式护理模式在学龄期Tourette综合征(Tourette syndrome,TS)患儿中的应用效果。方法:选择2024年1月至12月我院收治的学龄期TS患儿60例为研究对象,采用随机数字表法分为2组,各30例。对照组采用常规...目的:探讨基于诺丁斯关怀教育理论的亲情式护理模式在学龄期Tourette综合征(Tourette syndrome,TS)患儿中的应用效果。方法:选择2024年1月至12月我院收治的学龄期TS患儿60例为研究对象,采用随机数字表法分为2组,各30例。对照组采用常规护理模式,观察组在对照组基础上采用基于诺丁斯关怀教育理论的亲情式护理模式。比较2组护理效果(总有效率)、临床症状[Yale-Brown强迫量表(Yale Global Tic Severity Scale,Y-BOCS)、耶鲁抽动症整体严重程度量表(Yale-Brown Obsessive Compulsive Scale,YGTSS)、中文版注意缺陷多动障碍评定量表-父母版(Swanson,Nolan,and Pelham Rating Scale,SNAP-Ⅳ)]、智力水平[中国-韦氏儿童智力量表(Chinese version of Wechsler Intelligence Scale for Children,C-WISC)]、自我意识[Piers-Harris儿童自我意识量表(Piers-Harris Children's Self-Concept Scale,PHCCS)]、生活质量[儿少主观生活质量问卷(Inventory of Subjective Life Quality,ISLQ)]评分及家属对护理的总满意度。结果:观察组护理总有效率高于对照组(P<0.05);护理后观察组YGTSS、Y-BOCS、SNAP-Ⅳ评分低于对照组(P<0.05),C-WISC、PHCCS、ISLQ评分高于对照组(P<0.05);观察组家属对护理的总满意度高于对照组(P<0.05)。结论:基于诺丁斯关怀教育理论的亲情式护理模式能有效改善学龄期TS患儿的临床症状,可能通过榜样示范、关怀对话和正向证实等途径提升其智力水平和自我意识,从而显著提高生活质量及家属满意度。展开更多
OBJECTIVE:To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome.METHODS:We randomly divided 600 patients at a ratio of 1∶1∶1 i...OBJECTIVE:To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome.METHODS:We randomly divided 600 patients at a ratio of 1∶1∶1 into three groups:group A(acupuncture combined with atlantoaxial joint bone setting therapy group),group B(acupuncture group),and group C(tiapride group).After two months of treatment,the Yale global tic severity scale(YGTSS)score reduction,improvement in social function impairment,clinical efficacy,and long-term efficacy in the three groups were compared.RESULTS:After treatment,in the analysis of YGTSS score reduction,social function impairment improvement,the clinical control rate,and long-term efficacy,the results were all Group A>Group B>Group C,with a statistically significant difference(P<0.05).However,the total clinical efficacy of treatment in group A(94.9%)was not significantly different from that in group B(91.8%).Adverse reactions did not occur in groups A and B,and several adverse reactions occurred in 29%(n=58)of the group C patients.CONCLUSION:Compared with traditional drug therapy,acupuncture combined with atlantoaxial joint bone setting therapy has better clinical and long-term efficacy.This treatment strategy can improve the social function of children and prevent adverse reactions to drugs.展开更多
目的图雷特综合征(Tourette syndrome,TS)是一类起病于儿童青少年时期的神经发育障碍。有部分患者经过多种药物系统治疗,症状无改善,本研究探讨导致疾病难治性的相关因素。方法使用美国精神障碍诊断与统计手册第4版(Diagnostic and Stat...目的图雷特综合征(Tourette syndrome,TS)是一类起病于儿童青少年时期的神经发育障碍。有部分患者经过多种药物系统治疗,症状无改善,本研究探讨导致疾病难治性的相关因素。方法使用美国精神障碍诊断与统计手册第4版(Diagnostic and Statistical Manual of Mental Disorders,Forth Edition,DSM-IV)、综合抽动严重程度量表(Yale Global Tic Severity Scale,YGTSS)对患者进行诊断与评估。随访6个月,根据疗效将患者分为难治性和非难治性患者,进行单因素及多元回归分析寻找导致疾病难治的危险因素。结果单因素分析显示,母孕期不良事件、出生时危险因素、既往重大疾病史、家族史、特殊饮食偏好、依从性、抽动首发部位、各类共患病、年龄、起病年龄、病程、运动抽动及发声抽动次数及频率、发声抽动强度与复杂性、干扰及缺损是TS难治性的相关因素。进一步多元回归分析显示,母孕期不良事件、依从性、起病年龄、病程、发声强度、共患强迫障碍及情绪障碍是TS难治性的相关因素。结论TS难治性的相关因素包括母孕期不良事件(包括严重妊娠反应、吸烟、严重躯体疾病、精神疾病、长期精神刺激、物理损伤、堕胎未成、先兆流产等)、依从性差、起病年龄较早、病程较长、共患强迫障碍、情绪障碍、发声抽动强度评分高。展开更多
文摘目的:探讨基于诺丁斯关怀教育理论的亲情式护理模式在学龄期Tourette综合征(Tourette syndrome,TS)患儿中的应用效果。方法:选择2024年1月至12月我院收治的学龄期TS患儿60例为研究对象,采用随机数字表法分为2组,各30例。对照组采用常规护理模式,观察组在对照组基础上采用基于诺丁斯关怀教育理论的亲情式护理模式。比较2组护理效果(总有效率)、临床症状[Yale-Brown强迫量表(Yale Global Tic Severity Scale,Y-BOCS)、耶鲁抽动症整体严重程度量表(Yale-Brown Obsessive Compulsive Scale,YGTSS)、中文版注意缺陷多动障碍评定量表-父母版(Swanson,Nolan,and Pelham Rating Scale,SNAP-Ⅳ)]、智力水平[中国-韦氏儿童智力量表(Chinese version of Wechsler Intelligence Scale for Children,C-WISC)]、自我意识[Piers-Harris儿童自我意识量表(Piers-Harris Children's Self-Concept Scale,PHCCS)]、生活质量[儿少主观生活质量问卷(Inventory of Subjective Life Quality,ISLQ)]评分及家属对护理的总满意度。结果:观察组护理总有效率高于对照组(P<0.05);护理后观察组YGTSS、Y-BOCS、SNAP-Ⅳ评分低于对照组(P<0.05),C-WISC、PHCCS、ISLQ评分高于对照组(P<0.05);观察组家属对护理的总满意度高于对照组(P<0.05)。结论:基于诺丁斯关怀教育理论的亲情式护理模式能有效改善学龄期TS患儿的临床症状,可能通过榜样示范、关怀对话和正向证实等途径提升其智力水平和自我意识,从而显著提高生活质量及家属满意度。
基金Supported by Traditional Chinese medicine foundation of Zhejiang province:Clinical Study on the Correlation Between Tourette Syndrome and Anatomical Changes in the Atlantoaxial Joint(2010ZB162)Medical Health Science and Technology Project of Zhejiang Provincial Health Commission:Study on Protein Fingerprinting of Tourette Syndrome(2011KYB142)+1 种基金Renowned Traditional Chinese Medicine Expert Inheritance Studio Construction Project of Zhejiang province(No.GZS2020049)Key Disciplines of Traditional Chinese Medicine Foundation of Zhejiang Province(2012-XK-D20)。
文摘OBJECTIVE:To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome.METHODS:We randomly divided 600 patients at a ratio of 1∶1∶1 into three groups:group A(acupuncture combined with atlantoaxial joint bone setting therapy group),group B(acupuncture group),and group C(tiapride group).After two months of treatment,the Yale global tic severity scale(YGTSS)score reduction,improvement in social function impairment,clinical efficacy,and long-term efficacy in the three groups were compared.RESULTS:After treatment,in the analysis of YGTSS score reduction,social function impairment improvement,the clinical control rate,and long-term efficacy,the results were all Group A>Group B>Group C,with a statistically significant difference(P<0.05).However,the total clinical efficacy of treatment in group A(94.9%)was not significantly different from that in group B(91.8%).Adverse reactions did not occur in groups A and B,and several adverse reactions occurred in 29%(n=58)of the group C patients.CONCLUSION:Compared with traditional drug therapy,acupuncture combined with atlantoaxial joint bone setting therapy has better clinical and long-term efficacy.This treatment strategy can improve the social function of children and prevent adverse reactions to drugs.
文摘目的图雷特综合征(Tourette syndrome,TS)是一类起病于儿童青少年时期的神经发育障碍。有部分患者经过多种药物系统治疗,症状无改善,本研究探讨导致疾病难治性的相关因素。方法使用美国精神障碍诊断与统计手册第4版(Diagnostic and Statistical Manual of Mental Disorders,Forth Edition,DSM-IV)、综合抽动严重程度量表(Yale Global Tic Severity Scale,YGTSS)对患者进行诊断与评估。随访6个月,根据疗效将患者分为难治性和非难治性患者,进行单因素及多元回归分析寻找导致疾病难治的危险因素。结果单因素分析显示,母孕期不良事件、出生时危险因素、既往重大疾病史、家族史、特殊饮食偏好、依从性、抽动首发部位、各类共患病、年龄、起病年龄、病程、运动抽动及发声抽动次数及频率、发声抽动强度与复杂性、干扰及缺损是TS难治性的相关因素。进一步多元回归分析显示,母孕期不良事件、依从性、起病年龄、病程、发声强度、共患强迫障碍及情绪障碍是TS难治性的相关因素。结论TS难治性的相关因素包括母孕期不良事件(包括严重妊娠反应、吸烟、严重躯体疾病、精神疾病、长期精神刺激、物理损伤、堕胎未成、先兆流产等)、依从性差、起病年龄较早、病程较长、共患强迫障碍、情绪障碍、发声抽动强度评分高。
