Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tu...Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tumor were divided into three groups: prevention treatment (PT) group (n=23 cases),post chemotherapy treatment (PCT) group( n=22 cases), Western medicine (WM) group ( n=18 cases). The patients in PT, PCT and WM groups were treated respectively from the fifth day on before chemotherapy and from the first day on after chemotherapy, 18 days in all. The patients in WM group were administered Batilol and Leucogen from the first day on after chemotherapy. Changes of leukocytes and immunoglobulin before and after treatment were observed. Results: 1) Acupoint injection of Astragalus Root injectio could increase the number of leukocytes and immunoglobulin content and its effect was better than that of Western medicine (P<0.05); 2) The effect of PT group was better than that of PCT group in preventing and treating virulent and side effects of chemotherapy (P<0.05). Conclusion: It should be stressed on prevention of malignant tumor by using acupoint injection of Astragalus Root for relieving virulent and side effects of chemotherapy.展开更多
目的研究火针治疗膝骨关节炎的临床应用特点。方法检索中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库、PubMed、Embase、Web of Science核心合集数据库、Cochrane Library建库至2024年12月收录的火针治疗膝骨关节炎...目的研究火针治疗膝骨关节炎的临床应用特点。方法检索中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库、PubMed、Embase、Web of Science核心合集数据库、Cochrane Library建库至2024年12月收录的火针治疗膝骨关节炎的临床文献,建立数据库并进行频次统计、关联规则和聚类分析。结果纳入文献77篇,处方77首,腧穴27个,高频腧穴为犊鼻、内膝眼等,常用经脉是足阳明胃经和足太阴脾经,腧穴多分布于膝周,关联规则中支持度最高的穴对是内膝眼-犊鼻,聚类分析得出4个聚类群:犊鼻-内膝眼-阳陵泉-梁丘-血海-阿是穴-足三里-阴陵泉、鹤顶、膝阳关、关元-悬钟。最常使用的针具规格、临床操作及时效性参数:毫火针、0.30~0.35 mm、40 mm、红至发白、针身前中段、≤5 mm、点刺法、隔日1次、10~15次、4周、不留针。结论火针治疗膝骨关节炎以局部取穴为主,注重毫火针和点刺法的使用,选择合适的治疗时机,为临床应用提供依据。展开更多
Neuro D plays a key regulatory effect on differentiation of neural stem cells into mature neurons in the brain.Thus,we assumed that electroacupuncture at Baihui（DU20） acupoint in newborn rats exposed to in utero fet...Neuro D plays a key regulatory effect on differentiation of neural stem cells into mature neurons in the brain.Thus,we assumed that electroacupuncture at Baihui（DU20） acupoint in newborn rats exposed to in utero fetal distress would influence expression of Neuro D.Electroacupuncture at Baihui was performed for 20 minutes on 3-day-old（Day 3） newborn Sprague-Dawley rats exposed to in utero fetal distress;electroacupuncture parameters consisted of sparse and dense waves at a frequency of 2–10 Hz.Real-time fluorescent quantitative PCR results demonstrated that m RNA expression of Neuro D,a molecule that indicates Neuro D,increased with prolonged time in brains of newborn rats,and peaked on Day 22.The level of m RNA expression was similar between Day 16 and Day 35.These findings suggest that electro acupuncture at Baihui acupoint could effectively increase m RNA expression of molecules involved in Neuro D in the brains of newborn rats exposed to in utero fetal distress.展开更多
文摘Objective: To investigate the suitable time of treating virulent and side effects of chemotherapy for malignant tumor by acupoint injection of Astragalus Root injection. Methods: Sixty three patients with malignant tumor were divided into three groups: prevention treatment (PT) group (n=23 cases),post chemotherapy treatment (PCT) group( n=22 cases), Western medicine (WM) group ( n=18 cases). The patients in PT, PCT and WM groups were treated respectively from the fifth day on before chemotherapy and from the first day on after chemotherapy, 18 days in all. The patients in WM group were administered Batilol and Leucogen from the first day on after chemotherapy. Changes of leukocytes and immunoglobulin before and after treatment were observed. Results: 1) Acupoint injection of Astragalus Root injectio could increase the number of leukocytes and immunoglobulin content and its effect was better than that of Western medicine (P<0.05); 2) The effect of PT group was better than that of PCT group in preventing and treating virulent and side effects of chemotherapy (P<0.05). Conclusion: It should be stressed on prevention of malignant tumor by using acupoint injection of Astragalus Root for relieving virulent and side effects of chemotherapy.
基金supported by the Natural Science Foundation of Fujian Province of China,No.2015J01133the Professor Academic Development Foundation of Fujian Medical University of China,No.JS11003
文摘Neuro D plays a key regulatory effect on differentiation of neural stem cells into mature neurons in the brain.Thus,we assumed that electroacupuncture at Baihui（DU20） acupoint in newborn rats exposed to in utero fetal distress would influence expression of Neuro D.Electroacupuncture at Baihui was performed for 20 minutes on 3-day-old（Day 3） newborn Sprague-Dawley rats exposed to in utero fetal distress;electroacupuncture parameters consisted of sparse and dense waves at a frequency of 2–10 Hz.Real-time fluorescent quantitative PCR results demonstrated that m RNA expression of Neuro D,a molecule that indicates Neuro D,increased with prolonged time in brains of newborn rats,and peaked on Day 22.The level of m RNA expression was similar between Day 16 and Day 35.These findings suggest that electro acupuncture at Baihui acupoint could effectively increase m RNA expression of molecules involved in Neuro D in the brains of newborn rats exposed to in utero fetal distress.
文摘目的:探究择时穴位按摩联合情志干预在急性脑梗死(acute cerebral infarction,ACI)后康复期患者中的应用效果。方法:选择ACI后康复期患者96例,采用随机数字表法分成观察组和对照组各48例。对照组采用基础护理并给予情志干预,观察组在此基础上进行择时穴位按摩。比较两组患者干预前后语言功能[采用西方失语症评定法(Western aphasia battery,WAB)评估]、神经功能[采用美国国立卫生研究院卒中量表(national institutes of health stroke scale,NIHSS)评估]、运动功能[采用运动功能积分量表(fugl-meyer assessment,FMA)评估]、焦虑状态[采用焦虑自评量表(self-rating anxiety scale,SAS)评估]、抑郁状态[采用抑郁自评量表(self-rating depression scale,SDS)评估]、自我护理能力量表[采用自我护理能力量表(exercise of self-care agency scale,ESCA)评估]及生活质量[采用世界卫生组织生存质量量表简表(world health organization quality of life-brief version,WHOQOL-BREF)评估],并评估两组患者的护理满意度。结果:干预后,两组患者WAB评分、FMA上肢及下肢评分、ESCA评分、WHOQOL-BREF评分均较干预前升高(P<0.05),NIHSS评分、SAS评分、SDS评分均较干预前降低(P<0.05);且观察组上述各项指标的改善程度均优于对照组(P<0.05)。观察组操作技能、护理态度、沟通技巧维度评分均高于对照组(P<0.05),两组健康教育、出院指导维度评分比较,差异无统计学意义(P>0.05)。结论:择时穴位按摩联合情志干预可有效促进ACI康复期患者语言功能、神经功能及运动功能的恢复,改善其焦虑、抑郁等不良情绪,提升自护能力与生活质量,并提高患者对护理服务的满意度。
