BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also...BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also induces anxiety,which may hinder recovery.Although previous studies have addressed postoperative thirst,research specifically examining thirst experiences and nursing needs in older patients remains limited.AIM To explore thirst experiences and nursing needs of older PACU patients following gastrointestinal surgery,aiming to inform targeted interventions.METHODS This study employed a phenomenological approach within a qualitative research framework.A purposeful sampling method was used to select 12 older patients who underwent gastrointestinal surgery under general anesthesia at a tertiary hospital in Shanghai between November and December 2024.Data were collected through semi-structured interviews and analyzed using Colaizzi’s seven-step method.Themes were extracted from the interview data.RESULTS Analysis of the interview data identified four main themes and eight subthemes:(1)Intense sensations of thirst post-surgery(subjective experience of thirst and duration of thirst);(2)Emotional experiences of thirst-related discomfort(anxiety,irritability,and helplessness);(3)Practical challenges in relieving thirst(limitations of current interventions and nursing response time);and(4)Patient expectations of nursing care(desire for more timely interventions and expectation for more proactive attention from nursing staff).CONCLUSION Older patients frequently experience substantial thirst discomfort after gastrointestinal surgery under general anesthesia.A multidisciplinary perioperative intervention plan is essential to alleviate these symptoms and enhance postoperative comfort.展开更多
BACKGROUND Thirst management in convalescent patients recovering from a digestive surgery performed under general anesthesia requires attention.A simple,practical,and safe method can effectively relieve thirst symptom...BACKGROUND Thirst management in convalescent patients recovering from a digestive surgery performed under general anesthesia requires attention.A simple,practical,and safe method can effectively relieve thirst symptoms in such patients.AIM To evaluate the enhanced recovery after surgery(ERAS)-based evidence-based care(EBC)plus ice stimulation therapy for thirst management of convalescent patients following digestive surgery performed under general anesthesia.METHODS A total of 191 patients convalescing after digestive surgery performed under general anesthesia between March 2020 and February 2023 and experiencing thirst were selected.In total,89 patients and 102 patients in the control and research groups received routine care and ERAS-based EBC plus ice stimulation therapy,respectively.The following data were comparatively analyzed:(1)Thirst degree(thirst intensity numerical rating scale)and thirst distress(TD)degree(TD scale);(2)Oral mucosal wetness;(3)Unstimulated whole salivary flow rate(UWSFR);(4)Adverse reactions(palpitation,fatigue,chapped lips,and nausea and vomiting);and(5)Nursing satisfaction.RESULTS After nursing,thirst degree and distress were statistically lower in the research group than in the control group.Additionally,compared with the control group,the research group exhibited a lower degree of oral mucosal wetness,higher UWSFR,fewer adverse reactions,and more total nursing satisfaction.CONCLUSION ERAS-based EBC plus ice stimulation therapy can effectively alleviate thirst in convalescent patients recovering from a digestive surgery performed under general anesthesia.It can alleviate xerostomia symptoms,reduce adverse reactions,and improve patient comfort.展开更多
AIM: To contrast the effects of various modifications of body fluid volumes on thirst as reported by healthy volunteers. METHODS: Ten male volunteers aged between 19 and 37 years(mean 22 years) underwent four experime...AIM: To contrast the effects of various modifications of body fluid volumes on thirst as reported by healthy volunteers. METHODS: Ten male volunteers aged between 19 and 37 years(mean 22 years) underwent four experiments each, which comprised infusion of 400-800 m L of acetated Ringer's solution and intake of 600 m L of tap water. Half of the experiments were preceded by volume depletion(median 1.7 L) with furosemide. A visual analogue scale(0-100 mm) was used to assess perceived thirst during each experiment. RESULTS: Volume depletion(P < 0.001) and tap water(P < 0.03) both affected thirst by 13 mm per L of fluid, whereas spontaneous diuresis and infusion of Ringer's acetate did not significantly change the thirst rating(multiple regressions). More detailed analyses showed that the volume depletion increased the median(25th-75th percentiles) thirst rating from 28 mm(21-43) to 59 mm(46-72, P < 0.001) while no change occurred in those who were only slightly thirsty(< 30 mm) before the volume depletion began. Ringer's solution alleviated thirst in those who were very thirsty, but tended to increase thirst in the volunteers who were not thirsty before the infusion. Similarly, hydration with tap water decreased thirst(by 24 mm, P < 0.04) in those who were thirsty(> 60 mm) while the others reported no change.展开更多
Thirst, which provides the motivation to drink, is an important component of the coordinated sequence of physiological responses that maintain the volume and composition of body fluids. Special structures in the centr...Thirst, which provides the motivation to drink, is an important component of the coordinated sequence of physiological responses that maintain the volume and composition of body fluids. Special structures in the central nervous system like periventricular organs detect changes in these parameters continuously. The present study investigated the interaction between dopaminergic and angiotensinergic systems on water intake in adult male rats. Intracerebroventricular (ICV) injections were carried out in all experiments after 24 h deprivation of water intake. After the deprivation interval, the volume of consumed water was measured for 1h. Administration the angiotensinergic (AT1) receptor antagonist Losartan (45 μg/rat), and the dopaminergic antagonist Chlorpromazine (40 μg/rat) significantly decreased water intake when compared to saline-treated controls. In contrast, ICV microinjection of the dopaminergic agonist Bromocriptine (10 μg/rat) significantly increased water intake when compared to saline-treated controls. ICV injection of Bromocriptine 15min after Losartan administration was able to attenuate the inhibitory effect of Losartan on water intake, whereas administration of Chlorpromazine 15 min after Losartan was unable to change the Losartan effect. These results suggest that the dopaminergic system interactions with the angiotensinergic system to regulate water intake through circumventricular organs. Dopaminergic and angiotensinergic neurons can monitor and regulate water intake via the stimulatory and inhibitory effects on each other, respectively.展开更多
China accounts for more than 20 percent of the world’s global energy demand.As it is known to all that China surpassed the U.S.to become the world’s biggest energy consumer in 2009.Today the race is still neck and n...China accounts for more than 20 percent of the world’s global energy demand.As it is known to all that China surpassed the U.S.to become the world’s biggest energy consumer in 2009.Today the race is still neck and neck.CNPC in running for Iran energy projects Chinese oil giant among 29 firms to bid for tenders as a nation recovers from international sanctions展开更多
Objective: to investigate the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabetic nephropathy by observing the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabe...Objective: to investigate the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabetic nephropathy by observing the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabetic nephropathy patients with deficiency of spleen and kidney and blood stasis blocking collaterals. Methods: 60 cases of diabetic nephropathy diagnosed in the First Affiliated Hospital of Traditional Chinese Medicine of Guangxi University were randomly divided into treatment group and control group, 30 cases in each group. The control group was given losartan potassium tablets, and the treatment group was given cough relieving glucose-lowering prescription on this basis. The changes of CHOL, TG, LDL-C, CFR, BUN, SCR and 24-hour urinary protein were detected at the first, second and third month, respectively. Results: the index of cholesterol, triglyceride and low density lipoprotein cholesterol decreased in the treatment group after treatment (P < 0.05), but not in the control group before and after treatment (P > 0.05). Conclusion: it can effectively relieve clinical symptoms, regulate blood glucose, improve abnormal lipid metabolism, and improve glomerular filtration rate, urinary microalbumin and other indicators of renal function, and delay the deterioration of renal function.展开更多
IMAGINE Beijingers drinking water brought to the capital from more than 1,000 km away. from the Danjiangkou Reservoir on a branch of the Yangtze River in Hubei Province! Incredible but now it becomes true.
目的:重症监护病房(Intensive Care Unit,ICU)经口气管插管患者因机械通气、禁食等因素易诱发口渴不适,管理不当可导致焦虑、非计划性拔管等不良事件发生。本研究旨在构建ICU经口气管插管患者口渴管理的审查指标,了解最佳证据的临床应...目的:重症监护病房(Intensive Care Unit,ICU)经口气管插管患者因机械通气、禁食等因素易诱发口渴不适,管理不当可导致焦虑、非计划性拔管等不良事件发生。本研究旨在构建ICU经口气管插管患者口渴管理的审查指标,了解最佳证据的临床应用现状,并通过系统性分析,识别和评估影响证据转化的障碍因素,以促进临床实践的改进。方法:根据已发表的ICU经口气管插管患者口渴管理的最佳证据,通过严格的文献质量评价,对汇总的26条最佳证据进行证据适用性分析并制订审查指标,在江苏省无锡市某三甲医院ICU环境下进行基线审查,以评估当前实践与最佳证据之间的差距。结果:最终对适用的17条证据制订了16个审查指标。审查结果显示:11个审查指标的执行率低于60%,其中9个执行率为0。障碍因素主要集中于护理人员开展证据转化过程中,未充分重视口渴管理,对相关知识了解不全面,科室缺乏口渴评估工具,科室没有随时可调配使用的口渴保湿材料及缺乏具体的口腔护理保湿推荐方案,科室未及时更新口渴相关的流程规范,缺乏与家属宣教、沟通口渴相关的宣教材料等。结论:ICU经口气管插管患者口渴管理的临床实践与最佳证据之间存在较大差距。临床护理人员应积极应用最佳证据,改善ICU经口气管插管患者的口渴症状。展开更多
文摘BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also induces anxiety,which may hinder recovery.Although previous studies have addressed postoperative thirst,research specifically examining thirst experiences and nursing needs in older patients remains limited.AIM To explore thirst experiences and nursing needs of older PACU patients following gastrointestinal surgery,aiming to inform targeted interventions.METHODS This study employed a phenomenological approach within a qualitative research framework.A purposeful sampling method was used to select 12 older patients who underwent gastrointestinal surgery under general anesthesia at a tertiary hospital in Shanghai between November and December 2024.Data were collected through semi-structured interviews and analyzed using Colaizzi’s seven-step method.Themes were extracted from the interview data.RESULTS Analysis of the interview data identified four main themes and eight subthemes:(1)Intense sensations of thirst post-surgery(subjective experience of thirst and duration of thirst);(2)Emotional experiences of thirst-related discomfort(anxiety,irritability,and helplessness);(3)Practical challenges in relieving thirst(limitations of current interventions and nursing response time);and(4)Patient expectations of nursing care(desire for more timely interventions and expectation for more proactive attention from nursing staff).CONCLUSION Older patients frequently experience substantial thirst discomfort after gastrointestinal surgery under general anesthesia.A multidisciplinary perioperative intervention plan is essential to alleviate these symptoms and enhance postoperative comfort.
文摘BACKGROUND Thirst management in convalescent patients recovering from a digestive surgery performed under general anesthesia requires attention.A simple,practical,and safe method can effectively relieve thirst symptoms in such patients.AIM To evaluate the enhanced recovery after surgery(ERAS)-based evidence-based care(EBC)plus ice stimulation therapy for thirst management of convalescent patients following digestive surgery performed under general anesthesia.METHODS A total of 191 patients convalescing after digestive surgery performed under general anesthesia between March 2020 and February 2023 and experiencing thirst were selected.In total,89 patients and 102 patients in the control and research groups received routine care and ERAS-based EBC plus ice stimulation therapy,respectively.The following data were comparatively analyzed:(1)Thirst degree(thirst intensity numerical rating scale)and thirst distress(TD)degree(TD scale);(2)Oral mucosal wetness;(3)Unstimulated whole salivary flow rate(UWSFR);(4)Adverse reactions(palpitation,fatigue,chapped lips,and nausea and vomiting);and(5)Nursing satisfaction.RESULTS After nursing,thirst degree and distress were statistically lower in the research group than in the control group.Additionally,compared with the control group,the research group exhibited a lower degree of oral mucosal wetness,higher UWSFR,fewer adverse reactions,and more total nursing satisfaction.CONCLUSION ERAS-based EBC plus ice stimulation therapy can effectively alleviate thirst in convalescent patients recovering from a digestive surgery performed under general anesthesia.It can alleviate xerostomia symptoms,reduce adverse reactions,and improve patient comfort.
文摘AIM: To contrast the effects of various modifications of body fluid volumes on thirst as reported by healthy volunteers. METHODS: Ten male volunteers aged between 19 and 37 years(mean 22 years) underwent four experiments each, which comprised infusion of 400-800 m L of acetated Ringer's solution and intake of 600 m L of tap water. Half of the experiments were preceded by volume depletion(median 1.7 L) with furosemide. A visual analogue scale(0-100 mm) was used to assess perceived thirst during each experiment. RESULTS: Volume depletion(P < 0.001) and tap water(P < 0.03) both affected thirst by 13 mm per L of fluid, whereas spontaneous diuresis and infusion of Ringer's acetate did not significantly change the thirst rating(multiple regressions). More detailed analyses showed that the volume depletion increased the median(25th-75th percentiles) thirst rating from 28 mm(21-43) to 59 mm(46-72, P < 0.001) while no change occurred in those who were only slightly thirsty(< 30 mm) before the volume depletion began. Ringer's solution alleviated thirst in those who were very thirsty, but tended to increase thirst in the volunteers who were not thirsty before the infusion. Similarly, hydration with tap water decreased thirst(by 24 mm, P < 0.04) in those who were thirsty(> 60 mm) while the others reported no change.
文摘Thirst, which provides the motivation to drink, is an important component of the coordinated sequence of physiological responses that maintain the volume and composition of body fluids. Special structures in the central nervous system like periventricular organs detect changes in these parameters continuously. The present study investigated the interaction between dopaminergic and angiotensinergic systems on water intake in adult male rats. Intracerebroventricular (ICV) injections were carried out in all experiments after 24 h deprivation of water intake. After the deprivation interval, the volume of consumed water was measured for 1h. Administration the angiotensinergic (AT1) receptor antagonist Losartan (45 μg/rat), and the dopaminergic antagonist Chlorpromazine (40 μg/rat) significantly decreased water intake when compared to saline-treated controls. In contrast, ICV microinjection of the dopaminergic agonist Bromocriptine (10 μg/rat) significantly increased water intake when compared to saline-treated controls. ICV injection of Bromocriptine 15min after Losartan administration was able to attenuate the inhibitory effect of Losartan on water intake, whereas administration of Chlorpromazine 15 min after Losartan was unable to change the Losartan effect. These results suggest that the dopaminergic system interactions with the angiotensinergic system to regulate water intake through circumventricular organs. Dopaminergic and angiotensinergic neurons can monitor and regulate water intake via the stimulatory and inhibitory effects on each other, respectively.
文摘China accounts for more than 20 percent of the world’s global energy demand.As it is known to all that China surpassed the U.S.to become the world’s biggest energy consumer in 2009.Today the race is still neck and neck.CNPC in running for Iran energy projects Chinese oil giant among 29 firms to bid for tenders as a nation recovers from international sanctions
文摘Objective: to investigate the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabetic nephropathy by observing the clinical effect of quench thirst and Jiangtang prescription on stage ⅲ diabetic nephropathy patients with deficiency of spleen and kidney and blood stasis blocking collaterals. Methods: 60 cases of diabetic nephropathy diagnosed in the First Affiliated Hospital of Traditional Chinese Medicine of Guangxi University were randomly divided into treatment group and control group, 30 cases in each group. The control group was given losartan potassium tablets, and the treatment group was given cough relieving glucose-lowering prescription on this basis. The changes of CHOL, TG, LDL-C, CFR, BUN, SCR and 24-hour urinary protein were detected at the first, second and third month, respectively. Results: the index of cholesterol, triglyceride and low density lipoprotein cholesterol decreased in the treatment group after treatment (P < 0.05), but not in the control group before and after treatment (P > 0.05). Conclusion: it can effectively relieve clinical symptoms, regulate blood glucose, improve abnormal lipid metabolism, and improve glomerular filtration rate, urinary microalbumin and other indicators of renal function, and delay the deterioration of renal function.
文摘IMAGINE Beijingers drinking water brought to the capital from more than 1,000 km away. from the Danjiangkou Reservoir on a branch of the Yangtze River in Hubei Province! Incredible but now it becomes true.
文摘目的:重症监护病房(Intensive Care Unit,ICU)经口气管插管患者因机械通气、禁食等因素易诱发口渴不适,管理不当可导致焦虑、非计划性拔管等不良事件发生。本研究旨在构建ICU经口气管插管患者口渴管理的审查指标,了解最佳证据的临床应用现状,并通过系统性分析,识别和评估影响证据转化的障碍因素,以促进临床实践的改进。方法:根据已发表的ICU经口气管插管患者口渴管理的最佳证据,通过严格的文献质量评价,对汇总的26条最佳证据进行证据适用性分析并制订审查指标,在江苏省无锡市某三甲医院ICU环境下进行基线审查,以评估当前实践与最佳证据之间的差距。结果:最终对适用的17条证据制订了16个审查指标。审查结果显示:11个审查指标的执行率低于60%,其中9个执行率为0。障碍因素主要集中于护理人员开展证据转化过程中,未充分重视口渴管理,对相关知识了解不全面,科室缺乏口渴评估工具,科室没有随时可调配使用的口渴保湿材料及缺乏具体的口腔护理保湿推荐方案,科室未及时更新口渴相关的流程规范,缺乏与家属宣教、沟通口渴相关的宣教材料等。结论:ICU经口气管插管患者口渴管理的临床实践与最佳证据之间存在较大差距。临床护理人员应积极应用最佳证据,改善ICU经口气管插管患者的口渴症状。
