ObjectiveTo present the geographical map of malaria and identify some of the important environmental factors of this disease in Sistan and Baluchistan province, Iran.MethodsWe used the registered malaria data to compu...ObjectiveTo present the geographical map of malaria and identify some of the important environmental factors of this disease in Sistan and Baluchistan province, Iran.MethodsWe used the registered malaria data to compute the standard incidence rates (SIRs) of malaria in different areas of Sistan and Baluchistan province for a nine-year period (from 2001 to 2009). Statistical analyses consisted of two different parts: geographical mapping of malaria incidence rates, and modeling the environmental factors. The empirical Bayesian estimates of malaria SIRs were utilized for geographical mapping of malaria and a Poisson random effects model was used for assessing the effect of environmental factors on malaria SIRs.ResultsIn general, 64 926 new cases of malaria were registered in Sistan and Baluchistan Province from 2001 to 2009. Among them, 42 695 patients (65.8%) were male and 22 231 patients (34.2%) were female. Modeling the environmental factors showed that malaria incidence rates had positive relationship with humidity, elevation, average minimum temperature and average maximum temperature, while rainfall had negative effect on malaria SIRs in this province.ConclusionsThe results of the present study reveals that malaria is still a serious health problem in Sistan and Baluchistan province, Iran. Geographical map and related environmental factors of malaria can help the health policy makers to intervene in high risk areas more efficiently and allocate the resources in a proper manner.展开更多
Background: Liver weight is a complex trait, controlled by polygenic factors and differs within populations. Dissecting the genetic architecture underlying these variations will facilitate the search for key role cand...Background: Liver weight is a complex trait, controlled by polygenic factors and differs within populations. Dissecting the genetic architecture underlying these variations will facilitate the search for key role candidate genes involved directly in the hepatomegaly process and indirectly involved in related diseases etiology.Methods: Liver weight of 506 mice generated from 39 different Collaborative Cross(CC) lines with both sexes at age 20 weeks old was determined using an electronic balance. Genomic DNA of the CC lines was genotyped with high-density single nucleotide polymorphic markers.Results: Statistical analysis revealed a significant(P < 0.05) variation of liver weight between the CC lines, with broad sense heritability(H^2) of 0.32 and genetic coefficient of variation(CV_G) of 0.28. Subsequently, quantitative trait locus(QTL) mapping was performed, and results showed a significant QTL only for females on chromosome 8 at genomic interval 88.61-93.38 Mb(4.77 Mb). Three suggestive QTL were mapped at chromosomes 4, 12 and 13. The four QTL were designated as LWL1-LWL4 referring to liver weight loci 1-4 on chromosomes 8, 4, 12 and 13,respectively.Conclusion: To our knowledge, this report presents, for the first time, the utilization of the CC for mapping QTL associated with baseline liver weight in mice. Our findings demonstrate that liver weight is a complex trait controlled by multiple genetic factors that differ significantly between sexes.展开更多
Image encryption using chaotic maps has been established a great way. The study shows that a number of functional architecture has already been proposed that utilize the process of diffusion and confusion. However, pe...Image encryption using chaotic maps has been established a great way. The study shows that a number of functional architecture has already been proposed that utilize the process of diffusion and confusion. However, permutation and diffusion are considered as two separate stages, both requiring image-scanning to obtain pixel values. If these two stages are mutual, the duplicate scanning effort can be minimized and the encryption can be accelerated. This paper presents a technique which replaces the traditional preprocessing complex system and utilizes the basic operations like confusion, diffusion which provide same or better encryption using cascading of 3D standard and 3D cat map. We generate diffusion template using 3D standard map and rotate image by using vertically and horizontally red and green plane of the input image. We then shuffle the red, green, and blue plane by using 3D Cat map and standard map. Finally the Image is encrypted by performing XOR operation on the shuffled image and diffusion template. Theoretical analyses and computer simulations on the basis of Key space Analysis, statistical analysis, histogram analysis, Information entropy analysis, Correlation Analysis and Differential Analysis confirm that the new algorithm that minimizes the possibility of brute force attack for decryption and very fast for practical image展开更多
An-Najaf province is situated in south-western part of Iraq. It is 70 meters above the sea level in the dry desert environment. The city is considered as one of the most important cities in Iraq, facing a fast populat...An-Najaf province is situated in south-western part of Iraq. It is 70 meters above the sea level in the dry desert environment. The city is considered as one of the most important cities in Iraq, facing a fast population growth and continuous development in constructions such as residential complexes, hotels, bridges and shopping malls. Soil investigation data for An-Najaf Province (An-Najaf and Kufa cities) from 464 boreholes drilled by the Na-tional Centre for Construction Laboratories & Researches (NCCLR)/Babylon laboratory were used in this research. The data were analysed and possessed using Excel program then represented on the Geographical Information System (GIS) program by Inverse Distance Weighted (IDW) tool to create an allowable bearing capacity map for the soil at depths 0 - 2 meters. The allowable bearing capacity is one of the most important soil characteristics to be considered when making a database for An-Najaf city soil. Geographical Information System GIS program enables to create reliable database for any characteristic and it is one of the best programs to produce an accurate map and allow ease in dealing with it. Those maps cover all the studied areas and by using contour lines, approximate values for no-data areas can be obtained. The results show that the allowable bearing capacity range is 5 - 20 Ton/m2 for both An-Najaf and Kufa cities. Kufa city has the range 5 - 9 Ton/m2. An-Najaf city has the range 7 - 18 at the center, 8 - 10 Ton/m2 at the north eastern part, 7 - 14 Ton/m2 for the north western part, 6 - 12 Ton/m2 at the south eastern and 12 - 19 Ton/m2 at the south western.展开更多
Guwahati, the major city in the North Eastern region of India is growing rapidly in every aspect with major infrastructures like sports complex, educational institutions, hospitals, flyovers, multiplex halls, etc. Kno...Guwahati, the major city in the North Eastern region of India is growing rapidly in every aspect with major infrastructures like sports complex, educational institutions, hospitals, flyovers, multiplex halls, etc. Knowledge of the subsurface soil condition is necessary to ensure the structural safety and serviceability of the above mentioned structures before any construction. Therefore, contour maps of Standard penetration test N value, ground water table and shear wave velocity map using Geographical Information System (GIS) platform will be of great help to the foundation designers at the initial stage for site selection and preliminary foundation design under static and seismic condition. Contour maps of Standard penetration test N value at different depth and average contour map of N value of Guwahati city have been prepared. Standard penetration Test N values and depth of water table were taken from a data base of 200 boreholes up to 30 meter depth to prepare N value contour map of Guwahati city. A regression equation between shear wave velocity V<sub>s</sub> and Standard penetration test N value based on twenty seven previous similar correlations was also developed. This regression equation was used to determine shear wave velocity of Guwahati city. The average shear wave velocities for 30 m depth for all locations had been determined and used to generate map on (GIS) platform. Other subsurface geotechnical information of Guwahati city like soil classification and depth to water level from ground surface is also presented in the form of GIS based maps in order to form a data base.展开更多
文摘ObjectiveTo present the geographical map of malaria and identify some of the important environmental factors of this disease in Sistan and Baluchistan province, Iran.MethodsWe used the registered malaria data to compute the standard incidence rates (SIRs) of malaria in different areas of Sistan and Baluchistan province for a nine-year period (from 2001 to 2009). Statistical analyses consisted of two different parts: geographical mapping of malaria incidence rates, and modeling the environmental factors. The empirical Bayesian estimates of malaria SIRs were utilized for geographical mapping of malaria and a Poisson random effects model was used for assessing the effect of environmental factors on malaria SIRs.ResultsIn general, 64 926 new cases of malaria were registered in Sistan and Baluchistan Province from 2001 to 2009. Among them, 42 695 patients (65.8%) were male and 22 231 patients (34.2%) were female. Modeling the environmental factors showed that malaria incidence rates had positive relationship with humidity, elevation, average minimum temperature and average maximum temperature, while rainfall had negative effect on malaria SIRs in this province.ConclusionsThe results of the present study reveals that malaria is still a serious health problem in Sistan and Baluchistan province, Iran. Geographical map and related environmental factors of malaria can help the health policy makers to intervene in high risk areas more efficiently and allocate the resources in a proper manner.
基金Israeli Centers of Research ExcellenceWellcome Trust,Grant/Award Number:085906/Z/08/Z,075491/Z/04,090532/Z/09/Z+1 种基金Edmond J.Safra Center for Bioinformatics at Tel-Aviv UniversityTel-Aviv University
文摘Background: Liver weight is a complex trait, controlled by polygenic factors and differs within populations. Dissecting the genetic architecture underlying these variations will facilitate the search for key role candidate genes involved directly in the hepatomegaly process and indirectly involved in related diseases etiology.Methods: Liver weight of 506 mice generated from 39 different Collaborative Cross(CC) lines with both sexes at age 20 weeks old was determined using an electronic balance. Genomic DNA of the CC lines was genotyped with high-density single nucleotide polymorphic markers.Results: Statistical analysis revealed a significant(P < 0.05) variation of liver weight between the CC lines, with broad sense heritability(H^2) of 0.32 and genetic coefficient of variation(CV_G) of 0.28. Subsequently, quantitative trait locus(QTL) mapping was performed, and results showed a significant QTL only for females on chromosome 8 at genomic interval 88.61-93.38 Mb(4.77 Mb). Three suggestive QTL were mapped at chromosomes 4, 12 and 13. The four QTL were designated as LWL1-LWL4 referring to liver weight loci 1-4 on chromosomes 8, 4, 12 and 13,respectively.Conclusion: To our knowledge, this report presents, for the first time, the utilization of the CC for mapping QTL associated with baseline liver weight in mice. Our findings demonstrate that liver weight is a complex trait controlled by multiple genetic factors that differ significantly between sexes.
文摘Image encryption using chaotic maps has been established a great way. The study shows that a number of functional architecture has already been proposed that utilize the process of diffusion and confusion. However, permutation and diffusion are considered as two separate stages, both requiring image-scanning to obtain pixel values. If these two stages are mutual, the duplicate scanning effort can be minimized and the encryption can be accelerated. This paper presents a technique which replaces the traditional preprocessing complex system and utilizes the basic operations like confusion, diffusion which provide same or better encryption using cascading of 3D standard and 3D cat map. We generate diffusion template using 3D standard map and rotate image by using vertically and horizontally red and green plane of the input image. We then shuffle the red, green, and blue plane by using 3D Cat map and standard map. Finally the Image is encrypted by performing XOR operation on the shuffled image and diffusion template. Theoretical analyses and computer simulations on the basis of Key space Analysis, statistical analysis, histogram analysis, Information entropy analysis, Correlation Analysis and Differential Analysis confirm that the new algorithm that minimizes the possibility of brute force attack for decryption and very fast for practical image
文摘An-Najaf province is situated in south-western part of Iraq. It is 70 meters above the sea level in the dry desert environment. The city is considered as one of the most important cities in Iraq, facing a fast population growth and continuous development in constructions such as residential complexes, hotels, bridges and shopping malls. Soil investigation data for An-Najaf Province (An-Najaf and Kufa cities) from 464 boreholes drilled by the Na-tional Centre for Construction Laboratories & Researches (NCCLR)/Babylon laboratory were used in this research. The data were analysed and possessed using Excel program then represented on the Geographical Information System (GIS) program by Inverse Distance Weighted (IDW) tool to create an allowable bearing capacity map for the soil at depths 0 - 2 meters. The allowable bearing capacity is one of the most important soil characteristics to be considered when making a database for An-Najaf city soil. Geographical Information System GIS program enables to create reliable database for any characteristic and it is one of the best programs to produce an accurate map and allow ease in dealing with it. Those maps cover all the studied areas and by using contour lines, approximate values for no-data areas can be obtained. The results show that the allowable bearing capacity range is 5 - 20 Ton/m2 for both An-Najaf and Kufa cities. Kufa city has the range 5 - 9 Ton/m2. An-Najaf city has the range 7 - 18 at the center, 8 - 10 Ton/m2 at the north eastern part, 7 - 14 Ton/m2 for the north western part, 6 - 12 Ton/m2 at the south eastern and 12 - 19 Ton/m2 at the south western.
文摘Guwahati, the major city in the North Eastern region of India is growing rapidly in every aspect with major infrastructures like sports complex, educational institutions, hospitals, flyovers, multiplex halls, etc. Knowledge of the subsurface soil condition is necessary to ensure the structural safety and serviceability of the above mentioned structures before any construction. Therefore, contour maps of Standard penetration test N value, ground water table and shear wave velocity map using Geographical Information System (GIS) platform will be of great help to the foundation designers at the initial stage for site selection and preliminary foundation design under static and seismic condition. Contour maps of Standard penetration test N value at different depth and average contour map of N value of Guwahati city have been prepared. Standard penetration Test N values and depth of water table were taken from a data base of 200 boreholes up to 30 meter depth to prepare N value contour map of Guwahati city. A regression equation between shear wave velocity V<sub>s</sub> and Standard penetration test N value based on twenty seven previous similar correlations was also developed. This regression equation was used to determine shear wave velocity of Guwahati city. The average shear wave velocities for 30 m depth for all locations had been determined and used to generate map on (GIS) platform. Other subsurface geotechnical information of Guwahati city like soil classification and depth to water level from ground surface is also presented in the form of GIS based maps in order to form a data base.
