Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz ba...Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz band,which utilizes the tunable properties of Dirac semimetals(DSM)to create a novel multilayer structure.By incorporating both geometric and propagating phases into the metasurface design,we can effectively control the electromagnetic wave.When the Fermi level(EF)of the DSM is set at 6 meV,the electromagnetic wave is manipulated by the gold patch embedded in the DSM film,operating at a frequency of 1.3 THz.When the EF of the DSM is set at 80 meV,the electromagnetic wave is manipulated by the DSM patch,operating at a frequency of 1.4 THz.Both modes enable independent control of beam splitting under left-rotating circularly polarized(LCP)and rightrotating circularly polarized(RCP)wave excitation,resulting in the generation of vortex beams with distinct orbital angular momentum(OAM)modes.The findings of this study hold significant potential for enhancing information capacity and polarization multiplexing techniques in wireless communications.展开更多
The properties of cancer stem cells(CSCs),such as self-renewal,drug resistance,and metastasis,have been indicated to be responsible for the poor prognosis of patients with colon cancers.The epigenetic regulatory netwo...The properties of cancer stem cells(CSCs),such as self-renewal,drug resistance,and metastasis,have been indicated to be responsible for the poor prognosis of patients with colon cancers.The epigenetic regulatory network plays a crucial role in CSC properties.Regulatory non-coding RNA(ncRNA),including microRNAs,long noncoding RNAs,and circular RNAs,have an important influence on cell physiopathology.They modulate cells by regulating gene expression in different ways.This review discusses the basic characteristics and the physiological functions of colorectal cancer(CRC)stem cells.Elucidation of these ncRNAs will help us understand the pathological mechanism of CRC progression,and they could become a new target for cancer treatment.展开更多
This paper proposes a simple method to achieve the optical transfer function of a circular pupil wavefront coding system with a separable phase mask in Cartesian coordinates. Based on the stationary phase method, the ...This paper proposes a simple method to achieve the optical transfer function of a circular pupil wavefront coding system with a separable phase mask in Cartesian coordinates. Based on the stationary phase method, the optical transfer function of the circular pupil system can be easily obtained from the optical transfer function of the rectangular pupil system by modifying the cut-off frequency and the on-axial modulation transfer function. Finally, a system with a cubic phase mask is used as an example to illustrate the way to achieve the optical transfer function of the circular pupil system from the rectangular pupil system.展开更多
We study embeddings of the n-dimensional hypercube into the circuit with 2nvertices.We prove that the circular wirelength attains a minimum by gray coding;that was called the CT conjecture by Chavez and Trapp(Discrete...We study embeddings of the n-dimensional hypercube into the circuit with 2nvertices.We prove that the circular wirelength attains a minimum by gray coding;that was called the CT conjecture by Chavez and Trapp(Discrete Applied Mathematics,1998).This problem had claimed to be settled by Ching-Jung Guu in her doctoral dissertation“The circular wirelength problem for hypercubes”(University of California,Riverside,1997).Many argue there are gaps in her proof.We eliminate the gaps in her dissertation.展开更多
Koetzig put forward a question on strongly-regular self-complementary graphs, that is, for any natural number k, whether there exists a strongLy-regular self- complementary graph whose order is 4k ＋ 1, where 4k ＋ 1 ...Koetzig put forward a question on strongly-regular self-complementary graphs, that is, for any natural number k, whether there exists a strongLy-regular self- complementary graph whose order is 4k ＋ 1, where 4k ＋ 1 = x^2 ＋ y^2, x and y are positive integers; what is the minimum number that made there exist at least two non-isomorphic strongly-regular self-complementary graphs. In this paper, we use two famous lemmas to generalize the existential conditions for strongly-regular self-complementary circular graphs with 4k ＋ 1 orders.展开更多
Interaction between multiple curved rigid line and circular inclusion in antiplane loading condition was considered. Two kinds of elementary solutions corresponding to a concentrated force applying at inclusion and ma...Interaction between multiple curved rigid line and circular inclusion in antiplane loading condition was considered. Two kinds of elementary solutions corresponding to a concentrated force applying at inclusion and matrix material respectively were presented. Utilizing the elementary solutions and taking density function of traction difference along curved rigid line, a group of weakly singular integral equations with log kernels can be obtained. After the numerical solution of the integral equations, the discrete values of density functions of traction difference are obtainable. So stress singularity coefficients at rigid line tips can be calculated, and several numerical examples are given.展开更多
In this paper the authors explore the Global Positioning System （GPS） signal acquisition and tracking algorithms used in software GPS receiver. Acquisition time is the most important parameter in evaluating the perf...In this paper the authors explore the Global Positioning System （GPS） signal acquisition and tracking algorithms used in software GPS receiver. Acquisition time is the most important parameter in evaluating the performance of a software GPS receiver in terms of its speed. A trade-off study is done to seek a good balance between the acquisition accuracy and the processing time. The frequency-domain acquisition method by circular correlation, used in a software GPS receiver, has been improved by studying the power spectrum of the Coarse Acquisition （C/A） code alone. The analysis of C/A code reveals that its power spectrum is symmetrical; hence only half the points are required to perform circular correlation. Besides, either half of the spectrum is asymmetrical where a larger amount of power is concentrated in almost one-quarter of the spectrum on its either sides. This further reduces the number of points used to perform correlation. Comparative results of MATLAB simulation of full-size, half-size and quarter-size circular correlation done on actual data stored on hard disk are provided, and they agree with those obtained using GPS receiver. Further reduction in acquisition time has been achieved by investigating the effect of length of the noncoherent pre-integration period. The improved acquisition methods pave way for further development of new algorithms to enhance software GPS receiver performance.展开更多
背景:近几年有很多关于外泌体非编码RNA与妊娠期糖尿病发生机制的研究,但缺乏不同来源尤其是胎盘来源外泌体的最新系统综述。目的:文章对微小RNA、长链非编码RNA和环状RNA以及外泌体在妊娠期糖尿病中的变化情况及对疾病发生发展的可能...背景:近几年有很多关于外泌体非编码RNA与妊娠期糖尿病发生机制的研究,但缺乏不同来源尤其是胎盘来源外泌体的最新系统综述。目的:文章对微小RNA、长链非编码RNA和环状RNA以及外泌体在妊娠期糖尿病中的变化情况及对疾病发生发展的可能作用进行综述,为临床妊娠期糖尿病的早期筛查与治疗提供潜在靶标。方法:从PubMed、Web of Science、中国知网、万方数据及维普数据库进行非编码RNA或外泌体非编码RNA与妊娠期糖尿病相关文献进行检索,最终纳入74篇文献进行综述。结果与结论:①非编码RNA通过调节各种生理功能参与了妊娠期糖尿病的发生发展,为妊娠期糖尿病的研究提供了新的方向。②外泌体在人体中广泛存在,红细胞、上皮细胞和胎盘细胞等均可分泌外泌体,这些不同来源外泌体中的非编码RNA被证明可以在妊娠期糖尿病的发病机制、诊断以及治疗方法中发挥一定的作用。③微小RNA与妊娠期糖尿病:外周血微小RNA在妊娠期糖尿病中的作用主要是影响滋养层细胞、胰腺β细胞功能以及妊娠期糖尿病血糖水平;胎盘微小RNA可反映妊娠期糖尿病的严重程度,并损伤滋养层细胞的功能。④长链非编码RNA与妊娠期糖尿病:外周血长链非编码RNA可以通过磷脂酰肌醇3激酶/蛋白激酶B通路诱导胰岛素抵抗并且有可能为妊娠期糖尿病的诊断与治疗提供新的思路;胎盘长链非编码RNA可以调控妊娠期糖尿病胎盘滋养层细胞增殖迁移,促进妊娠期糖尿病的发生发展。⑤环状RNA与妊娠期糖尿病:外周血和胎盘环状RNA可通过损伤胎盘滋养层细胞增殖迁移与代谢等功能诱导糖尿病的发生发展。⑥外泌体非编码RNA与妊娠期糖尿病:外周血外泌体非编码RNA可影响妊娠期糖尿病血糖水平和葡萄糖稳态,通过影响胎盘功能参与妊娠期糖尿病的发生发展。⑦非编码RNA有潜力成为妊娠期糖尿病早期诊断的标志物,此外工程化的外泌体能更好地实现妊娠期糖尿病的靶向治疗等,这些最新信息为妊娠期糖尿病的基础研究和临床转化提供了参考依据。⑧未来还需改进外周血外泌体的提取和纯化方法,并排除种族、饮食和体力活动等因素以提高结果的可重复性,而循环非编码RNA及外泌体在妊娠期糖尿病的预测和诊断中的临床应用还需要更多的前瞻性临床研究。展开更多
文摘Multiple functional metasurfaces with high information capacity have attracted considerable attention from researchers.This study proposes a 2-bit tunable spin-decoupled coded metasurface designed for the terahertz band,which utilizes the tunable properties of Dirac semimetals(DSM)to create a novel multilayer structure.By incorporating both geometric and propagating phases into the metasurface design,we can effectively control the electromagnetic wave.When the Fermi level(EF)of the DSM is set at 6 meV,the electromagnetic wave is manipulated by the gold patch embedded in the DSM film,operating at a frequency of 1.3 THz.When the EF of the DSM is set at 80 meV,the electromagnetic wave is manipulated by the DSM patch,operating at a frequency of 1.4 THz.Both modes enable independent control of beam splitting under left-rotating circularly polarized(LCP)and rightrotating circularly polarized(RCP)wave excitation,resulting in the generation of vortex beams with distinct orbital angular momentum(OAM)modes.The findings of this study hold significant potential for enhancing information capacity and polarization multiplexing techniques in wireless communications.
文摘The properties of cancer stem cells(CSCs),such as self-renewal,drug resistance,and metastasis,have been indicated to be responsible for the poor prognosis of patients with colon cancers.The epigenetic regulatory network plays a crucial role in CSC properties.Regulatory non-coding RNA(ncRNA),including microRNAs,long noncoding RNAs,and circular RNAs,have an important influence on cell physiopathology.They modulate cells by regulating gene expression in different ways.This review discusses the basic characteristics and the physiological functions of colorectal cancer(CRC)stem cells.Elucidation of these ncRNAs will help us understand the pathological mechanism of CRC progression,and they could become a new target for cancer treatment.
基金Project supported by the Natural Science Foundation of Zhejiang Province,China (Grant No. Y1110455)the Scientific Research Fund of Educational Department of Zhejiang Province,China (Grant No. Y200909691)the Science Foundation of Zhejiang Sci-Tech University (Grant No. 0913849-Y)
文摘This paper proposes a simple method to achieve the optical transfer function of a circular pupil wavefront coding system with a separable phase mask in Cartesian coordinates. Based on the stationary phase method, the optical transfer function of the circular pupil system can be easily obtained from the optical transfer function of the rectangular pupil system by modifying the cut-off frequency and the on-axial modulation transfer function. Finally, a system with a cubic phase mask is used as an example to illustrate the way to achieve the optical transfer function of the circular pupil system from the rectangular pupil system.
文摘We study embeddings of the n-dimensional hypercube into the circuit with 2nvertices.We prove that the circular wirelength attains a minimum by gray coding;that was called the CT conjecture by Chavez and Trapp(Discrete Applied Mathematics,1998).This problem had claimed to be settled by Ching-Jung Guu in her doctoral dissertation“The circular wirelength problem for hypercubes”(University of California,Riverside,1997).Many argue there are gaps in her proof.We eliminate the gaps in her dissertation.
文摘Koetzig put forward a question on strongly-regular self-complementary graphs, that is, for any natural number k, whether there exists a strongLy-regular self- complementary graph whose order is 4k ＋ 1, where 4k ＋ 1 = x^2 ＋ y^2, x and y are positive integers; what is the minimum number that made there exist at least two non-isomorphic strongly-regular self-complementary graphs. In this paper, we use two famous lemmas to generalize the existential conditions for strongly-regular self-complementary circular graphs with 4k ＋ 1 orders.
文摘Interaction between multiple curved rigid line and circular inclusion in antiplane loading condition was considered. Two kinds of elementary solutions corresponding to a concentrated force applying at inclusion and matrix material respectively were presented. Utilizing the elementary solutions and taking density function of traction difference along curved rigid line, a group of weakly singular integral equations with log kernels can be obtained. After the numerical solution of the integral equations, the discrete values of density functions of traction difference are obtainable. So stress singularity coefficients at rigid line tips can be calculated, and several numerical examples are given.
文摘In this paper the authors explore the Global Positioning System （GPS） signal acquisition and tracking algorithms used in software GPS receiver. Acquisition time is the most important parameter in evaluating the performance of a software GPS receiver in terms of its speed. A trade-off study is done to seek a good balance between the acquisition accuracy and the processing time. The frequency-domain acquisition method by circular correlation, used in a software GPS receiver, has been improved by studying the power spectrum of the Coarse Acquisition （C/A） code alone. The analysis of C/A code reveals that its power spectrum is symmetrical; hence only half the points are required to perform circular correlation. Besides, either half of the spectrum is asymmetrical where a larger amount of power is concentrated in almost one-quarter of the spectrum on its either sides. This further reduces the number of points used to perform correlation. Comparative results of MATLAB simulation of full-size, half-size and quarter-size circular correlation done on actual data stored on hard disk are provided, and they agree with those obtained using GPS receiver. Further reduction in acquisition time has been achieved by investigating the effect of length of the noncoherent pre-integration period. The improved acquisition methods pave way for further development of new algorithms to enhance software GPS receiver performance.
文摘背景:近几年有很多关于外泌体非编码RNA与妊娠期糖尿病发生机制的研究,但缺乏不同来源尤其是胎盘来源外泌体的最新系统综述。目的:文章对微小RNA、长链非编码RNA和环状RNA以及外泌体在妊娠期糖尿病中的变化情况及对疾病发生发展的可能作用进行综述,为临床妊娠期糖尿病的早期筛查与治疗提供潜在靶标。方法:从PubMed、Web of Science、中国知网、万方数据及维普数据库进行非编码RNA或外泌体非编码RNA与妊娠期糖尿病相关文献进行检索,最终纳入74篇文献进行综述。结果与结论:①非编码RNA通过调节各种生理功能参与了妊娠期糖尿病的发生发展,为妊娠期糖尿病的研究提供了新的方向。②外泌体在人体中广泛存在,红细胞、上皮细胞和胎盘细胞等均可分泌外泌体,这些不同来源外泌体中的非编码RNA被证明可以在妊娠期糖尿病的发病机制、诊断以及治疗方法中发挥一定的作用。③微小RNA与妊娠期糖尿病:外周血微小RNA在妊娠期糖尿病中的作用主要是影响滋养层细胞、胰腺β细胞功能以及妊娠期糖尿病血糖水平;胎盘微小RNA可反映妊娠期糖尿病的严重程度,并损伤滋养层细胞的功能。④长链非编码RNA与妊娠期糖尿病:外周血长链非编码RNA可以通过磷脂酰肌醇3激酶/蛋白激酶B通路诱导胰岛素抵抗并且有可能为妊娠期糖尿病的诊断与治疗提供新的思路;胎盘长链非编码RNA可以调控妊娠期糖尿病胎盘滋养层细胞增殖迁移,促进妊娠期糖尿病的发生发展。⑤环状RNA与妊娠期糖尿病:外周血和胎盘环状RNA可通过损伤胎盘滋养层细胞增殖迁移与代谢等功能诱导糖尿病的发生发展。⑥外泌体非编码RNA与妊娠期糖尿病:外周血外泌体非编码RNA可影响妊娠期糖尿病血糖水平和葡萄糖稳态,通过影响胎盘功能参与妊娠期糖尿病的发生发展。⑦非编码RNA有潜力成为妊娠期糖尿病早期诊断的标志物,此外工程化的外泌体能更好地实现妊娠期糖尿病的靶向治疗等,这些最新信息为妊娠期糖尿病的基础研究和临床转化提供了参考依据。⑧未来还需改进外周血外泌体的提取和纯化方法,并排除种族、饮食和体力活动等因素以提高结果的可重复性,而循环非编码RNA及外泌体在妊娠期糖尿病的预测和诊断中的临床应用还需要更多的前瞻性临床研究。
