To the Editor:Abeleda et al.[1]recently argued in a perspective article that the Philippines should do better in order to achieve its goal of reducing schistosomiasis incidence to zero in humans,animals,and snails by ...To the Editor:Abeleda et al.[1]recently argued in a perspective article that the Philippines should do better in order to achieve its goal of reducing schistosomiasis incidence to zero in humans,animals,and snails by 2025[2,3].The authors appropriately ascribed the need to ramp up surveillance,WASH(water,sanitation,and hygiene),and veterinary efforts.In this letter,I would like to add to the discussion that the key to achieving schistosomiasis elimination may be strengthening the veterinary public health sector and framing mitigation efforts within the One Health lens.Schistosoma(S.)japonicum infection is a zoonotic disease and it affects more than 40 species of animals,including livestock animals like cattle,pigs,and water buffaloes,and pets like dogs[4].In the Philippines,the prevalence of infection in animal reservoirs remains largely unknown in most endemic areas due to the lack of concerted epidemiological efforts unlike what is being done in human hosts.In areas where studies have been done,infection rates are from less than 10%to 97%in water buffaloes tested[5-7].Indeed,as Abeleda et al.[1]argued,there is a need to do better on this front.展开更多
文摘金花茶组(Sect. Chrysanthae)植物具有很高的观赏价值,但其开花习性各不相同。为探究金花茶组植物成花机制,本研究以四季金花茶(Camellia perpetua)、金花茶(C. petelotii)和淡黄金花茶(C. flavida) 3种典型的金花茶为材料,克隆了控制成花转变的关键基因FLOWERING LOCUS T (FT)和CENTRORADIALIS1(CEN1)以及它们的启动子,对基因和启动子的结构特点进行分析,并通过RT-qPCR对三种金花茶不同组织中的FT和CEN1的表达进行定量分析。结果显示三种金花茶FT和CEN1编码的氨基酸序列极为相似,推测它们的功能可能相同。基因表达分析显示三种金花茶的FT基因主要在叶片中表达,在花芽、苞片中表达量较低,其中四季金花茶的CperFT基因在嫩叶及其叶柄和幼态叶的叶柄中表达量较高;三种金花茶CEN1主要在逐渐张开、显露色泽的花蕾中表达,且在花器官中表达量各不相同,在叶片、顶芽和花芽中的表达量相对较低。启动子序列分析显示,三种金花茶FT和CEN1启动子均具有不同数量的TATA-box和CAAT-box核心元件,同时激素响应、生物和非生物胁迫响应元件也存在差异。金花茶和四季金花茶的FT和CEN1启动子序列比较接近,淡黄金花茶CflaFT和CflaCEN1与它们相差较大。本研究结果表明三种金花茶开花习性的差异可能不是由FT和CEN1编码的蛋白功能差异引起的,很可能与它们的表达模式差异有关。
文摘To the Editor:Abeleda et al.[1]recently argued in a perspective article that the Philippines should do better in order to achieve its goal of reducing schistosomiasis incidence to zero in humans,animals,and snails by 2025[2,3].The authors appropriately ascribed the need to ramp up surveillance,WASH(water,sanitation,and hygiene),and veterinary efforts.In this letter,I would like to add to the discussion that the key to achieving schistosomiasis elimination may be strengthening the veterinary public health sector and framing mitigation efforts within the One Health lens.Schistosoma(S.)japonicum infection is a zoonotic disease and it affects more than 40 species of animals,including livestock animals like cattle,pigs,and water buffaloes,and pets like dogs[4].In the Philippines,the prevalence of infection in animal reservoirs remains largely unknown in most endemic areas due to the lack of concerted epidemiological efforts unlike what is being done in human hosts.In areas where studies have been done,infection rates are from less than 10%to 97%in water buffaloes tested[5-7].Indeed,as Abeleda et al.[1]argued,there is a need to do better on this front.
