The development of cost-effective,strong,and ductile alloys for various temperatures is crucial but challenging for the modern industry.In this study,we designed a series of novel L1_(2)-strengthened(Fe_(58.98)Ni_(31....The development of cost-effective,strong,and ductile alloys for various temperatures is crucial but challenging for the modern industry.In this study,we designed a series of novel L1_(2)-strengthened(Fe_(58.98)Ni_(31.7)Al_(6)Ti_(3)Zr_(0.1)C_(0.2)B_(0.02))_(100-x)Cr_(x)(x=0,4,8,and 13 at%)Fe-based medium-entropy alloys(MEAs).The alloy with 8%Cr content demonstrated optimal mechanical properties from-196℃to 700℃,outperforming numerous MEAs and austenitic stainless steels.At 25℃,it exhibited a yield strength and elongation of~843 MPa and 23%,respectively.Both strength and ductility improved as the temperature decreased from 25℃to-196℃.The excellent mechanical properties at 25℃are attributed to the synergistic effects of L1_(2)nanoprecipitates,dislocations,slip bands,and stacking faults.In the sample deformed at-196℃,Lomer-Cottrell locks were also observed.Furthermore,at 700℃,the MEA maintains a high yield strength of~766 MPa and elongations of 26%,which is attributed to the shearing of L1_(2)precipitate and dislocation slips.This study provides a foundation for developing advanced alloys for use across a wide temperature range.展开更多
Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening pa...Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%.展开更多
British Prime Minister Keir Starmer’s China visit has yielded a new commitment to a long-term stable comprehensive strategic partnership,with significant breakthroughs in financial cooperation including a newly estab...British Prime Minister Keir Starmer’s China visit has yielded a new commitment to a long-term stable comprehensive strategic partnership,with significant breakthroughs in financial cooperation including a newly established financial working group.THE four-day visit of British Prime Minister Keir Starmer to China-the first by a U.K.Prime Minister in eight years-has marked a significant step toward stabilizing and deepening bilateral relations.展开更多
Introducing B2 ordering can effectively improve the mechanical properties of lightweight refractory high-entropy alloys(LRHEAs).However,(Zr,Al)-enriched B2 precipitates generally reduce the ductility because their ord...Introducing B2 ordering can effectively improve the mechanical properties of lightweight refractory high-entropy alloys(LRHEAs).However,(Zr,Al)-enriched B2 precipitates generally reduce the ductility because their ordering characteristic is destroyed after dislocation shearing.Meanwhile,the local chemical order(LCO)cannot provide an adequate strengthening effect due to its small size.展开更多
With the increase in power of the industrial gas turbine and thrust-weight ratio of aeroengine,the conventional strengthening method of adding refractory elements into superalloys has become difficult to meet the dema...With the increase in power of the industrial gas turbine and thrust-weight ratio of aeroengine,the conventional strengthening method of adding refractory elements into superalloys has become difficult to meet the demands for the higher mechanical properties.A novel Ni-based superalloy was designed with enhanced strength and hardness based on the graphene nanosheets(GNs)synergistic in-situ nano-carbides strengthening in the present work.Nano-carbides were induced by in-situ reaction of the GNs with alloy powders during additive manufacturing.The microstructure and thermophysical properties of different alloys with 0.1wt.%GNs and without GNs were investigated by SEM,EBSD,TEM,differential scanning calorimetry(DSC),and small angle neutron scattering(SANS).Residual GNs were also detected by SANS and DSC.The nano-carbides are uniformly distributed in the matrix and combine with residual GNs to refine the cellular structure.Compared with the original alloy(ASE100),the hardness of the alloy with 0.1wt.%GNs(ASE100-0.1GN)is increased by 31 HV(from 315 HV to 346 HV),and the yield tensile strength is increased by 86 MPa(from 756 MPa to 842 MPa).The GNs react with alloy melt in the molten pools to generate nano-carbides under the Marangoni effect during manufacturing process.The dispersion nano-carbides are distributed at both grain boundaries and within grains,effectively hindering the movement of dislocation and enhancing the strength of alloy.展开更多
As a typical tungsten-based composite consisting of tungsten(W)particles and matrix phase,tungsten heavy alloys(WHAs)are extensively utilized in the military due to their exceptional strength and high density.However,...As a typical tungsten-based composite consisting of tungsten(W)particles and matrix phase,tungsten heavy alloys(WHAs)are extensively utilized in the military due to their exceptional strength and high density.However,the large grain size(>30μm)of powder metallurgy liquid phase sintered(LPS)WHAs and the low strength of the matrix phase limit the further improvement of the alloy.In this work,high-density ultrafine WHAs were fabricated by two-step low-temperature sintering,and the density of the alloy reached 17 g/cm^(3) with an average W particle size of 7.81μm.Additionally,the eutectic reaction be-tween Ni and Ta was controlled to generate dispersed nano-Ni_(3)Ta phases in situ in the matrix phase,fur-ther improving the strength of the alloy.Under the synergistic strengthening effect of fine-grain strength-ening,dispersion strengthening,and solid solution strengthening,the average ultimate tensile strength of the alloy reached 1190.39 MPa.At the same time,the alloy maintained good elongation with a total elon-gation of 20.8%due to the good co-grid interface orientation between the Ni_(3)Ta phase and the matrix phase.This study provides a new idea for developing high-strength WHAs and has a guiding significance for developing Ni-based alloys.展开更多
China National Intellectual Property Administration(CNIPA) issued the"Notice on Strengthening Management of Trademark Use"(Notice) on November 17,2025.This directive aims to guide the business community,part...China National Intellectual Property Administration(CNIPA) issued the"Notice on Strengthening Management of Trademark Use"(Notice) on November 17,2025.This directive aims to guide the business community,particularly the trademark users and trademark law practitioners,toward stricter compliance,focusing on curbing deceptive practices and enhancing fair competition.展开更多
Ni/TiAl composite brazed joints could significantly reduce the aircraft’s weight.However,low interfacial adhesion,coarse and brittle-hard intermetallic compounds(IMCs)seriously limited the application of Ni/TiAl comp...Ni/TiAl composite brazed joints could significantly reduce the aircraft’s weight.However,low interfacial adhesion,coarse and brittle-hard intermetallic compounds(IMCs)seriously limited the application of Ni/TiAl composite joints in the next generation of aerospace applications.So enhanced K4169/TiAl composite joints were investigated by vacuum brazed with(Ni_(53.33)Cr_(20)B_(16.67)Si_(10)/Zr_(25)Ti_(18.75)Ta_(12.5)Ni_(25)Cu_(18.75))composite filler metal(CFM)designed based on cluster-plus-glue-atom model.The shear strength of the joint reached 485 MPa,comparable to the 491 MPa of TiAl substrate.The flat and brittle-hard diffusion reaction layer between Zones I and II was eliminated,simultaneously generating CrB4 dispersion strengthening due to the CFM developed with the interfacial solid-liquid space-time hysteresis effect.In Zones II and III,IMCs all transformed into Niss(Cr,Fe)_([0–88]),Niss(Ti,Al)_([004]),and Niss(Zr,Si)_([11–2])of circular and oval shapes through isothermal solidification.Meanwhile,the residual stresses and hardness were distributed in reticulated cladding characteristics.Thereby,lattice distortion led to solid solution strengthening and increased plastic toughness through crack termination and bridging mechanisms,which inhibited dislocations from plugging and crack propagation.Various interfaces in ZoneⅣwere regulated into semi-and coherent interfaces.Ni3(Ti,Al)/(Ni,Ti,Al)and(Ni,Ti,Al)/AlNi_(2)Ti were composed of higher interfacial bonding energy(2.771 J/m^(2),2.547 J/m^(2))and Ni-Ni covalent bonds.Interfacial covalent bonding and large interfacial bonding energy coupling strengthened Zone IV.Consequently,cracks initiated at the(Ni,Ti,Al)[013]/Ti3Al_([010])and expanded rapidly into TiAl substrate.Therefore,applying this method to design CFMs and regulate the phase,grain morphology,and interface’s fine structure could provide new pathways for dissimilar hard-to-join metals.展开更多
This study demonstrates simultaneous enhancement of magnetic and mechanical properties in NdFeB magnets through Ti addition.The coercivity increases by 1.1 kOe without compromising remanence,while bending strength imp...This study demonstrates simultaneous enhancement of magnetic and mechanical properties in NdFeB magnets through Ti addition.The coercivity increases by 1.1 kOe without compromising remanence,while bending strength improves by 159.05%.Analytical results reveal that Ti predominantly combines with free B atoms to form TiB_(2)phases,which reduce the brittleness of grain boundary(GB)phase and impede dislocation motion.The superposition of stress fields around dislocations generates reactive forces that counteract external loads,thereby enhancing GB strength.Concurrently,B depletion in GB phases induces amorphous transformation,further enhancing boundary strength.A minor fraction of Ti incorporates into the main phase,enhancing covalent bond strength and forming a reinforced main phase.Additionally,Ti addition promotes grain refinement and increases GB density,significantly improving bending strength.The synergistic effects of heterogeneous phase formation,amorphous transformation,main phase reinforcement,and grain refinement collectively enable coordinated strengthening between the main phase and GBs.This multi-mechanism approach provides novel insights for mechanical property optimization in Nd FeB magnets.展开更多
Magnesium-lithium(Mg-Li) alloy,as the lightest metal structure material,has unparalleled market prospects in aerospace,weapons and equipment,electronic technology,transportation,and many other fields.However,it is har...Magnesium-lithium(Mg-Li) alloy,as the lightest metal structure material,has unparalleled market prospects in aerospace,weapons and equipment,electronic technology,transportation,and many other fields.However,it is hard to balance the superlight and high strength of Mg-Li alloy,and the inferior high-temperature strength and poor high-temperature stability limit the wide application of Mg-Li alloy.At present,the main methods to improve the mechanical properties of Mg-Li alloy are alloying,grain refinement,and compound strengthening.The domestic and overseas research progress in the strengthening and toughening methods and mechanisms of Mg-Li alloy are reviewed,and the future development of the high strength and high toughness Mg-Li alloy is prospected.展开更多
Refractory high/medium-entropy alloys(RH/MEAs)are known for their outstanding performance at el-evated temperatures;however,they usually exhibit poor room-temperature plasticity,which can be at-tributed to the non-uni...Refractory high/medium-entropy alloys(RH/MEAs)are known for their outstanding performance at el-evated temperatures;however,they usually exhibit poor room-temperature plasticity,which can be at-tributed to the non-uniform deformation that occurs at room temperature.Once cracks nucleate,they will rapidly propagate into vertical splitting cracks.Here,we introduce multiple phases including FCC and HCP phases into the NbMoTa RMEA via appropriate addition of carbon.The results show that multiple-phase synergy effectively suppresses non-uniform deformation,thereby delaying the onset of vertical splitting cracks.An optimal combination of compressive strength-plasticity is achieved by the(NbMoTa)_(92.5)C_(7.5) alloy.The significant improvement in room-temperature mechanical properties can be attributed to its hierarchical microstructure:in the mesoscale,the BCC matrix is divided by eutectic structures;while at the microscale,the BCC matrix is further refined by abundant lath-like FCC precipitates.The FCC precip-itates contain high-density stacking faults,acting as a dislocation source under compressive loading.The HCP phase in the eutectic microstructures,in turn,acts as a strong barrier to dislocation movement and simultaneously increases the dislocation storage capacity.These findings open a new route to tailor the microstructure and mechanical properties of RH/MEAs.展开更多
This paper examines the effect of Fe addition on the microstructure characterized by scanning electron microscopy/electron backscattered diffraction,neutron diffraction,and synchrotron X-ray tomography and the mechani...This paper examines the effect of Fe addition on the microstructure characterized by scanning electron microscopy/electron backscattered diffraction,neutron diffraction,and synchrotron X-ray tomography and the mechanical properties of Al-Mg-Mn-Fe-Cu alloys.The findings reveal that the microstructures of the alloys consisted of an Al matrix,Al_(6)(FeMn),and Al_(2)CuMg phase particles.The addition of Fe significantly increased the yield strength(YS),and ultimate tensile strength(UTS)of the alloys,while reducing elongation.The transformation of the 3D morphology of the Al_(6)(FeMn)phase from separated and fine particles with Chinese-script morphology to interconnected rod-like structure as Fe content increased from 0.1%to 0.8%.This strengthening effect was attributed to the slip lines being blocked at the vicinity of the inter-connected Fe-rich phase,leading to grain rotation and dislocation density increment around the Fe-rich phase,ultimately improving the strength of the alloys.However,the Fe-rich phases and Al_(2)CuMg phases were found to be prone to cracking under tensile stress,resulting in decreased elongation of the alloys.This study provides a potential application in the design and manufacturing of new non-heat-treatable Al alloys for the automotive industry.展开更多
To effectively regulate the grain boundary infiltration in CoCrFeMnNi high-entropy alloy(Cantor alloys,HEA)caused by the violent atomic interdiffusion,the higher configuration entropy on Cantor alloys surface was desi...To effectively regulate the grain boundary infiltration in CoCrFeMnNi high-entropy alloy(Cantor alloys,HEA)caused by the violent atomic interdiffusion,the higher configuration entropy on Cantor alloys surface was designed and realized via eutectic high-entropy(EHEA)transformation.Meanwhile,to effectively alleviate the residual stress caused by the notable difference in the thermal expansion coefficient(CTE)between Cantor alloys and Zr-3 alloys,a cladding layer was applied to the HEA surface using laser cladding technology of Nb,followed by brazing to Zr-3 alloys with Zr63.2Cu filler.The cladding layer’s microstructure comprised Nbss and FCC+(Co,Ni)_(2) Nb eutectic structure,resulting from an in-situ reaction between Cantor alloys and Nb.The Nbss and FCC demonstrated good plasticity,and the(Co,Ni)_(2) Nb Laves phase provided increased strength,endowing both good plastic deformation ability and strength of the cladding layer.Notably,the existence of EHEA in the laser cladding layer made the Cantor alloy entropy from 1.61 R to 1.77 R,greatly enhancing its thermal stability and suppressing the grave grain boundary infiltration.Joints produced via laser cladding with Nb-assisted brazing exhibited a complex microstructure(HEA/Nbss+FCC+(Co,Ni)_(2)Nb/(Zr,Nb)(Cr,Mn)_(2)+(Zr,Nb)ss/(Zr,Nb)_(2)(Cu,Ni,Co,Fe)+(Zr,Nb)(Cr,Mn)_(2)+(Zr,Nb)ss/Zr-3) and a significantly improved shear strength of 242.8 MPa at 1010℃ for 10 min,42.4%higher than that of directly brazed joints.This improvement was attributed to reduced grain boundary infiltration,alleviated residual stress due to CTE disparity,and eliminated micro-cracks in the brazing seam.This study presents an effective solution for reducing residual stresses and achieving reliable bonding between Cantor alloys and Zr-3 alloys,with potential applications in brazing CoCrFeNi-based HEA and Zr-3 due to the beneficial eutectic reaction between CoCrFeNi and Nb.展开更多
The microstructure evolution and strengthening mechanism of WE54 alloy with different hard-plate rolling(HPR)processes were systematically investigated.The results suggest that the mechanical properties of the as-roll...The microstructure evolution and strengthening mechanism of WE54 alloy with different hard-plate rolling(HPR)processes were systematically investigated.The results suggest that the mechanical properties of the as-rolled alloys are significantly enhanced compared to those of the as-cast alloy.When subjected to three rolling passes at 450℃ and 490℃,grain refinement occurs due to dynamic recrystallization.A mixed-grain structure is formed after a single pass rolling with a substantial reduction(65%)at 490℃.The dynamic recrystallization(DRX)mechanism of the alloy during the HPR includes continuous dynamic recrystallization(CDRX),discontinuous dynamic recrystallization(DDRX),and twin-induced recrystallization(TDRX).The WE54 alloy exhibits the highest strength after three passes of HPR at 450℃,with tensile strength and yield strength of 374 and 323 MPa,respectively.The significant improvement in the mechanical properties of the alloy is primarily attributed to fine-grain strengthening,solid solution strengthening,and dislocation strengthening.展开更多
The unique structure and formation mechanism of medium-entropy alloys(MEAs)generally result in bet-ter comprehensive properties than traditional alloys.However,the strength-ductility trade-offremains a bottleneck,whic...The unique structure and formation mechanism of medium-entropy alloys(MEAs)generally result in bet-ter comprehensive properties than traditional alloys.However,the strength-ductility trade-offremains a bottleneck,which limits their applications.In this study,we designed novel high-performance CrNiCu x MEAs with a heterophase composition by incorporating a Cu-rich phase,and they were fabricated using laser-directed energy deposition(LDED).The results show that synergistic strengthening from multiple phases significantly improved the mechanical properties of the alloys,resulting in a tensile strength of 675 MPa and a ductility of 34.4%,demonstrating an excellent combination of high tensile strength and ductility.The improved mechanical properties of the CrNiCu x medium-entropy alloys are primarily due to the heterophase interfacial strengthening mechanism.In the alloy,numerous semi-coherent and coher-ent interfaces formed between the Cr-rich phase,Cu-rich phase,and the matrix,creating extensive lattice distortions at the interfaces.An increase in the Cu-rich phase content promoted the interaction between phases,enhancing the strain energy of the alloy and the barrier strength of the interfaces.The calcu-latedτint values,ranging from approximately 5.92-6.69 GPa,are significantly higher than those found in traditional alloys,providing a benchmark for designing new high-performance medium-entropy alloys.展开更多
Fe-28Mn-(10-12)Al-(0.8-1.4)C(wt.%)steels were designed to investigate the influence of varying Al and C content on precipitation behavior ofκ-carbide and its contribution to the strength of high-Mn low-density steels...Fe-28Mn-(10-12)Al-(0.8-1.4)C(wt.%)steels were designed to investigate the influence of varying Al and C content on precipitation behavior ofκ-carbide and its contribution to the strength of high-Mn low-density steels.Results reveal that both Al and C elements promoteκ-carbide precipitation,with C having a more pronounced effect.In near-rapidly solidified 10Al steel strips,increasing C content from 0.8wt.%to 1.4wt.%raises theκ-carbide size from 9.6 nm to 38.2 nm,accompanied by volume fraction increase from 10.2vol.%to 29.8vol.%.In comparison,the average size and volume fraction ofκ-carbides in 12Al0.8C steel are only 11.4 nm and 17.8vol.%,respectively.Higher Al and C content reduces the lattice mismatch between austenite andκ-carbides,thus promoting nucleation ofκ-carbides.Notably,the increase in C content results in a greater reduction in the Gibbs free energy ofκ-carbide,leading to a stronger driving force forκ-carbide formation.Consequently,as the C content increases from 0.8wt.%to 1.4wt.%,the interaction betweenκ-carbides and dislocations transforms from particle cutting to bypassing,and the maximum precipitation strengthening ofκ-carbides reaches 583 MPa.The construction of the relationship between Al and C content andκ-carbide precipitation in this study would provide valuable insights for alloy design of high-Mn steels.展开更多
OBJECTIVE:To evaluate the 10-year therapeutic efficacy of Traditional Chinese Medicine(TCM)using the Strengthening Spleen and Draining Dampness therapy in the management of idiopathic membranous nephropathy(IMN).METHO...OBJECTIVE:To evaluate the 10-year therapeutic efficacy of Traditional Chinese Medicine(TCM)using the Strengthening Spleen and Draining Dampness therapy in the management of idiopathic membranous nephropathy(IMN).METHODS:A single-center,retrospective analysis was conducted on patients diagnosed with IMN who met predefined inclusion and exclusion criteria.Data were collected from the Department of Nephrology at Longhua Hospital,affiliated with Shanghai University of Traditional Chinese Medicine,between January 2007 and December 2011.Clinical parameters including 24-h urinary protein,serum albumin,serum creatinine,and estimated glomerular filtration rate(e GFR,EPI)were assessed at baseline and at 1,3,5,and 10 years of follow-up.The efficacy of the Strengthening Spleen and Draining Dampness therapy was analyzed using repeated measures analysis of variance(ANOVA).Kaplan-Meier survival curves and multivariate proportional hazards model(Cox regression models)were employed to identify factors associated with treatment outcomes.RESULTS:A total of 265 patients were included,with a median follow-up duration of 96 months(36,122).TCM treatment significantly reduced 24-h urinary protein levels(P<0.001),and increased serum albumin levels(P<0.001),while serum creatinine remained stable(P=0.187).Remission rates at 1,3,5,and 10 years were 52.81%,69.71%,68.39%,and 72.36%,respectively,and the rates of avoiding composite outcome events at the same intervals were 98.27%,94.29%,94.19%,and 93.50%.In the subgroup receiving TCM only,remission rates were 56.67%,84.44%,76.32%,and 82.86%.For patients treated initially with Western Medicine followed by TCM,the rates were 52.83%,65.85%,67.47%and 67.75%.In the cohort of patients who received TCM as their first-line therapy,remission rates were 49.23%,62.50%,61.76%,and 69.23%.Multivariate Cox regression analysis revealed that the duration of TCM treatment[hazard ratio(HR)=0.826,95%confidence interval(CI)(0.779,0.876),P<0.001],presence of hypertension[HR=1.912,95%CI(1.181,3.094),P=0.008],baseline serum albumin level[HR=0.930,95%CI(0.894,0.969),P<0.001],and the rate of serum albumin increase within the first year of treatment[HR=0.930,95%CI(0.909,0.957),P<0.001]were significantly associated with clinical outcomes.CONCLUSION:The Strengthening Spleen and Draining Dampness therapy demonstrated robust short-and longterm efficacy in treating IMN,with high rates of remission and renal survival over 10 years.Key factors influencing clinical remission included the duration of TCM treatment,baseline serum albumin levels,the presence of hypertension,and the rate of increase in serum albumin within the first year.These findings suggest that this TCM approach provides a viable long-term treatment option for IMN.展开更多
Martensite is an important microstructure in ultrahigh-strength steels,and enhancing the strength of martensitic steels often involves the introduction of precipitated phases within the martensitic matrix.Despite cons...Martensite is an important microstructure in ultrahigh-strength steels,and enhancing the strength of martensitic steels often involves the introduction of precipitated phases within the martensitic matrix.Despite considerable research efforts devoted to this area,a systematic summary of these advancements is lacking.This review focuses on the precipitates prevalent in ultrahigh-strength martensitic steel,primarily carbides(e.g.,MC,M_(2)C,and M_(3)C)and intermetallic compounds(e.g.,Ni Al,Ni_(3)X,and Fe_(2)Mo).The precipitation-strengthening effect of these precipitates on ultrahigh-strength martensitic steel is discussed from the aspects of heat treatment processes,microstructure of precipitate-strengthened martensite matrix,and mechanical performance.Finally,a perspective on the development of precipitation-strengthened martensitic steel is presented to contribute to the advancement of ultrahigh-strength martensitic steel.This review highlights significant findings,ongoing challenges,and opportunities in the development of ultrahigh-strength martensitic steel.展开更多
93W-4.9Ni-2.1Fe alloys strengthened by nanoscale ZrC particles were prepared by spark-plasma-sintering(SPS)and hot rotary swaging,separately.Results show that the addition of a small number of ZrC nanoparticles can re...93W-4.9Ni-2.1Fe alloys strengthened by nanoscale ZrC particles were prepared by spark-plasma-sintering(SPS)and hot rotary swaging,separately.Results show that the addition of a small number of ZrC nanoparticles can refine grains and increase the hardness of the WNiFe alloys,but hinder the formation of theγ-(Ni,Fe)phase during SPS.SPSed WNiFe and WNiFe-ZrC alloys are brittle at room temperature,while the swaged WNiFe and WNiFe-0.5ZrC(wt%)alloys are ductile.At 400°C,the swaged WNiFe-0.5ZrC alloy exhibits both higher tensile strength and better ductility than the swaged WNiFe.The nanoscale particles distributed in the W grains andγ-(Ni,Fe)phase provide a good pinning effect,which enhances the strength.The thermal conductivity of swaged WNiFe-0.5ZrC is only 71 W·m^(-1)·K^(-1)at room temperature,but it increases to about 100 W·m^(-1)·K^(-1)at 800°C,which is close to that of pure W(121 W·m^(-1)·K^(-1)).These results show the potential of WNiFe alloys as plasma-facing materials in fusion reactor.展开更多
The extraordinary strength of metal/graphene composites is significantly determined by the characteristic size,distribution and morphology of graphene.However,the effect of the graphene size/distribution on the mechan...The extraordinary strength of metal/graphene composites is significantly determined by the characteristic size,distribution and morphology of graphene.However,the effect of the graphene size/distribution on the mechanical properties and related strengthening mechanisms has not been fully elucidated.Herein,under the same volume fraction and distribution conditions of graphene,molecular dynamics simulations were used to investigate the effect of graphene sheet size on the hardness and deformation behavior of Cu/graphene composites under complex stress field.Two models of pure single crystalline Cu and graphene fully covered Cu matrix composite were constructed for comparison.The results show that the strengthening effect changes with varying the graphene sheet size.Besides the graphene dislocation blocking effect and the load-bearing effect,the deformation mechanisms change from stacking fault tetrahedron,dislocation bypassing and dislocation cutting to dislocation nucleation in turn with decreasing the graphene sheet size.The hardness of Cu/graphene composite,with the graphene sheet not completely covering the metal matrix,can even be higher than that of the fully covered composite.The extra strengthening mechanisms of dislocation bypassing mechanism and the stacking fault tetrahedra pinning dislocation mechanism contribute to the increase in hardness.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.52101053,52371078)。
文摘The development of cost-effective,strong,and ductile alloys for various temperatures is crucial but challenging for the modern industry.In this study,we designed a series of novel L1_(2)-strengthened(Fe_(58.98)Ni_(31.7)Al_(6)Ti_(3)Zr_(0.1)C_(0.2)B_(0.02))_(100-x)Cr_(x)(x=0,4,8,and 13 at%)Fe-based medium-entropy alloys(MEAs).The alloy with 8%Cr content demonstrated optimal mechanical properties from-196℃to 700℃,outperforming numerous MEAs and austenitic stainless steels.At 25℃,it exhibited a yield strength and elongation of~843 MPa and 23%,respectively.Both strength and ductility improved as the temperature decreased from 25℃to-196℃.The excellent mechanical properties at 25℃are attributed to the synergistic effects of L1_(2)nanoprecipitates,dislocations,slip bands,and stacking faults.In the sample deformed at-196℃,Lomer-Cottrell locks were also observed.Furthermore,at 700℃,the MEA maintains a high yield strength of~766 MPa and elongations of 26%,which is attributed to the shearing of L1_(2)precipitate and dislocation slips.This study provides a foundation for developing advanced alloys for use across a wide temperature range.
基金financial support of the National Natural Science Foundation of China(No.52371103)the Fundamental Research Funds for the Central Universities,China(No.2242023K40028)+1 种基金the Open Research Fund of Jiangsu Key Laboratory for Advanced Metallic Materials,China(No.AMM2023B01).financial support of the Research Fund of Shihezi Key Laboratory of AluminumBased Advanced Materials,China(No.2023PT02)financial support of Guangdong Province Science and Technology Major Project,China(No.2021B0301030005)。
文摘Oxide dispersion strengthened(ODS)alloys are extensively used owing to high thermostability and creep strength contributed from uniformly dispersed fine oxides particles.However,the existence of these strengthening particles also deteriorates the processability and it is of great importance to establish accurate processing maps to guide the thermomechanical processes to enhance the formability.In this study,we performed particle swarm optimization-based back propagation artificial neural network model to predict the high temperature flow behavior of 0.25wt%Al2O3 particle-reinforced Cu alloys,and compared the accuracy with that of derived by Arrhenius-type constitutive model and back propagation artificial neural network model.To train these models,we obtained the raw data by fabricating ODS Cu alloys using the internal oxidation and reduction method,and conducting systematic hot compression tests between 400 and800℃with strain rates of 10^(-2)-10 S^(-1).At last,processing maps for ODS Cu alloys were proposed by combining processing parameters,mechanical behavior,microstructure characterization,and the modeling results achieved a coefficient of determination higher than>99%.
文摘British Prime Minister Keir Starmer’s China visit has yielded a new commitment to a long-term stable comprehensive strategic partnership,with significant breakthroughs in financial cooperation including a newly established financial working group.THE four-day visit of British Prime Minister Keir Starmer to China-the first by a U.K.Prime Minister in eight years-has marked a significant step toward stabilizing and deepening bilateral relations.
基金supported by the National Natural Science Foundation of China(Nos.52171166 and U20A20231)the Natural Science Foundation of Hunan Province,China(Nos.2024JJ2060 and 2024JJ5406)+1 种基金the Key Laboratory of Materials in Dynamic Extremes of Sichuan Province(No.2023SCKT1102)the Postgraduate Scientific Research Innovation Project of National University of Defense Technology(No.XJJC2024065).
文摘Introducing B2 ordering can effectively improve the mechanical properties of lightweight refractory high-entropy alloys(LRHEAs).However,(Zr,Al)-enriched B2 precipitates generally reduce the ductility because their ordering characteristic is destroyed after dislocation shearing.Meanwhile,the local chemical order(LCO)cannot provide an adequate strengthening effect due to its small size.
基金sponsored by the Leading Project of Chinese Academy of Sciences(No.XDC0160000)the Fundamental Research Project of China National Nuclear Corporation(No.FK010261123429)the National Natural Science Foundation of China(No.12375305).
文摘With the increase in power of the industrial gas turbine and thrust-weight ratio of aeroengine,the conventional strengthening method of adding refractory elements into superalloys has become difficult to meet the demands for the higher mechanical properties.A novel Ni-based superalloy was designed with enhanced strength and hardness based on the graphene nanosheets(GNs)synergistic in-situ nano-carbides strengthening in the present work.Nano-carbides were induced by in-situ reaction of the GNs with alloy powders during additive manufacturing.The microstructure and thermophysical properties of different alloys with 0.1wt.%GNs and without GNs were investigated by SEM,EBSD,TEM,differential scanning calorimetry(DSC),and small angle neutron scattering(SANS).Residual GNs were also detected by SANS and DSC.The nano-carbides are uniformly distributed in the matrix and combine with residual GNs to refine the cellular structure.Compared with the original alloy(ASE100),the hardness of the alloy with 0.1wt.%GNs(ASE100-0.1GN)is increased by 31 HV(from 315 HV to 346 HV),and the yield tensile strength is increased by 86 MPa(from 756 MPa to 842 MPa).The GNs react with alloy melt in the molten pools to generate nano-carbides under the Marangoni effect during manufacturing process.The dispersion nano-carbides are distributed at both grain boundaries and within grains,effectively hindering the movement of dislocation and enhancing the strength of alloy.
基金supported by the National Natural Science Foundation of China(No.51701242,51931012)the Science and Technology Innovation Program of Hunan Province(No.2023RC3068).
文摘As a typical tungsten-based composite consisting of tungsten(W)particles and matrix phase,tungsten heavy alloys(WHAs)are extensively utilized in the military due to their exceptional strength and high density.However,the large grain size(>30μm)of powder metallurgy liquid phase sintered(LPS)WHAs and the low strength of the matrix phase limit the further improvement of the alloy.In this work,high-density ultrafine WHAs were fabricated by two-step low-temperature sintering,and the density of the alloy reached 17 g/cm^(3) with an average W particle size of 7.81μm.Additionally,the eutectic reaction be-tween Ni and Ta was controlled to generate dispersed nano-Ni_(3)Ta phases in situ in the matrix phase,fur-ther improving the strength of the alloy.Under the synergistic strengthening effect of fine-grain strength-ening,dispersion strengthening,and solid solution strengthening,the average ultimate tensile strength of the alloy reached 1190.39 MPa.At the same time,the alloy maintained good elongation with a total elon-gation of 20.8%due to the good co-grid interface orientation between the Ni_(3)Ta phase and the matrix phase.This study provides a new idea for developing high-strength WHAs and has a guiding significance for developing Ni-based alloys.
文摘China National Intellectual Property Administration(CNIPA) issued the"Notice on Strengthening Management of Trademark Use"(Notice) on November 17,2025.This directive aims to guide the business community,particularly the trademark users and trademark law practitioners,toward stricter compliance,focusing on curbing deceptive practices and enhancing fair competition.
基金financially supported by the National Natural Science Foundation of China(Nos.52275314 and 52075074).
文摘Ni/TiAl composite brazed joints could significantly reduce the aircraft’s weight.However,low interfacial adhesion,coarse and brittle-hard intermetallic compounds(IMCs)seriously limited the application of Ni/TiAl composite joints in the next generation of aerospace applications.So enhanced K4169/TiAl composite joints were investigated by vacuum brazed with(Ni_(53.33)Cr_(20)B_(16.67)Si_(10)/Zr_(25)Ti_(18.75)Ta_(12.5)Ni_(25)Cu_(18.75))composite filler metal(CFM)designed based on cluster-plus-glue-atom model.The shear strength of the joint reached 485 MPa,comparable to the 491 MPa of TiAl substrate.The flat and brittle-hard diffusion reaction layer between Zones I and II was eliminated,simultaneously generating CrB4 dispersion strengthening due to the CFM developed with the interfacial solid-liquid space-time hysteresis effect.In Zones II and III,IMCs all transformed into Niss(Cr,Fe)_([0–88]),Niss(Ti,Al)_([004]),and Niss(Zr,Si)_([11–2])of circular and oval shapes through isothermal solidification.Meanwhile,the residual stresses and hardness were distributed in reticulated cladding characteristics.Thereby,lattice distortion led to solid solution strengthening and increased plastic toughness through crack termination and bridging mechanisms,which inhibited dislocations from plugging and crack propagation.Various interfaces in ZoneⅣwere regulated into semi-and coherent interfaces.Ni3(Ti,Al)/(Ni,Ti,Al)and(Ni,Ti,Al)/AlNi_(2)Ti were composed of higher interfacial bonding energy(2.771 J/m^(2),2.547 J/m^(2))and Ni-Ni covalent bonds.Interfacial covalent bonding and large interfacial bonding energy coupling strengthened Zone IV.Consequently,cracks initiated at the(Ni,Ti,Al)[013]/Ti3Al_([010])and expanded rapidly into TiAl substrate.Therefore,applying this method to design CFMs and regulate the phase,grain morphology,and interface’s fine structure could provide new pathways for dissimilar hard-to-join metals.
基金financially supported by the National Natural Science Foundation of China(No.52361033)National Key Research and Development Program(No.2022YFB3505400)+6 种基金Ministry of Industry and Information Technology Heavy Rare Earth Special use of Sintered NdFeB Project(No.TC220H06J)Academic and Technical Leaders in Major Disciplines in Jiangxi Province(No.20225BCJ23007)Jiangxi Natural Science Foundation Youth Fund(No.20232BAB214011)the Young Elite Scientists Sponsorship Program by CAST(No.2022QNRC001)Research Projects of Ganjiang Innovation Academy,Chinese Academy of Sciences(No.E255J001)Science and Technology Major Project of Ganzhou(No.202101064871)Program for Excellent Young Talents(No.JXUSTQJYC2024003)
文摘This study demonstrates simultaneous enhancement of magnetic and mechanical properties in NdFeB magnets through Ti addition.The coercivity increases by 1.1 kOe without compromising remanence,while bending strength improves by 159.05%.Analytical results reveal that Ti predominantly combines with free B atoms to form TiB_(2)phases,which reduce the brittleness of grain boundary(GB)phase and impede dislocation motion.The superposition of stress fields around dislocations generates reactive forces that counteract external loads,thereby enhancing GB strength.Concurrently,B depletion in GB phases induces amorphous transformation,further enhancing boundary strength.A minor fraction of Ti incorporates into the main phase,enhancing covalent bond strength and forming a reinforced main phase.Additionally,Ti addition promotes grain refinement and increases GB density,significantly improving bending strength.The synergistic effects of heterogeneous phase formation,amorphous transformation,main phase reinforcement,and grain refinement collectively enable coordinated strengthening between the main phase and GBs.This multi-mechanism approach provides novel insights for mechanical property optimization in Nd FeB magnets.
基金the National Natural Science Foundation of China(Nos.51771115,51775334,51821001 and U2037601)the Joint Fund for Space Science and Technology(No.6141B06310106)。
文摘Magnesium-lithium(Mg-Li) alloy,as the lightest metal structure material,has unparalleled market prospects in aerospace,weapons and equipment,electronic technology,transportation,and many other fields.However,it is hard to balance the superlight and high strength of Mg-Li alloy,and the inferior high-temperature strength and poor high-temperature stability limit the wide application of Mg-Li alloy.At present,the main methods to improve the mechanical properties of Mg-Li alloy are alloying,grain refinement,and compound strengthening.The domestic and overseas research progress in the strengthening and toughening methods and mechanisms of Mg-Li alloy are reviewed,and the future development of the high strength and high toughness Mg-Li alloy is prospected.
基金financial support from the Na-tional Natural Science Foundation of China(No.52231006)National Key Research and Development Program of China(No.2017YFB0702003)the National Natural Science Foundation of China(No.51871217).
文摘Refractory high/medium-entropy alloys(RH/MEAs)are known for their outstanding performance at el-evated temperatures;however,they usually exhibit poor room-temperature plasticity,which can be at-tributed to the non-uniform deformation that occurs at room temperature.Once cracks nucleate,they will rapidly propagate into vertical splitting cracks.Here,we introduce multiple phases including FCC and HCP phases into the NbMoTa RMEA via appropriate addition of carbon.The results show that multiple-phase synergy effectively suppresses non-uniform deformation,thereby delaying the onset of vertical splitting cracks.An optimal combination of compressive strength-plasticity is achieved by the(NbMoTa)_(92.5)C_(7.5) alloy.The significant improvement in room-temperature mechanical properties can be attributed to its hierarchical microstructure:in the mesoscale,the BCC matrix is divided by eutectic structures;while at the microscale,the BCC matrix is further refined by abundant lath-like FCC precipitates.The FCC precip-itates contain high-density stacking faults,acting as a dislocation source under compressive loading.The HCP phase in the eutectic microstructures,in turn,acts as a strong barrier to dislocation movement and simultaneously increases the dislocation storage capacity.These findings open a new route to tailor the microstructure and mechanical properties of RH/MEAs.
基金support from the Natural Science Foundation of China(Nos.52104373,52074131,and 51974092)the Basic and Applied Basic Foundation of Guangdong Province(No.2020B1515120065)。
文摘This paper examines the effect of Fe addition on the microstructure characterized by scanning electron microscopy/electron backscattered diffraction,neutron diffraction,and synchrotron X-ray tomography and the mechanical properties of Al-Mg-Mn-Fe-Cu alloys.The findings reveal that the microstructures of the alloys consisted of an Al matrix,Al_(6)(FeMn),and Al_(2)CuMg phase particles.The addition of Fe significantly increased the yield strength(YS),and ultimate tensile strength(UTS)of the alloys,while reducing elongation.The transformation of the 3D morphology of the Al_(6)(FeMn)phase from separated and fine particles with Chinese-script morphology to interconnected rod-like structure as Fe content increased from 0.1%to 0.8%.This strengthening effect was attributed to the slip lines being blocked at the vicinity of the inter-connected Fe-rich phase,leading to grain rotation and dislocation density increment around the Fe-rich phase,ultimately improving the strength of the alloys.However,the Fe-rich phases and Al_(2)CuMg phases were found to be prone to cracking under tensile stress,resulting in decreased elongation of the alloys.This study provides a potential application in the design and manufacturing of new non-heat-treatable Al alloys for the automotive industry.
基金supported by the National Natural Science Foundation of China(Grant Nos.52275321 and 52205348)the Shandong Natural Science Foundation(Grant No.ZR2023JQ021)+3 种基金the Taishan Scholars Foundation of Shandong Province(No.tsqn 201812128)the Innovation Scientists and Technicians Troop Projects of Henan Province(No.204200510031)the Heilongjiang Touyan Innovation Team Program(No.HITTY-20190013)supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIP)(Nos.NRF-2021R1A2C3006662 and NRF-2022R1A5A1030054).
文摘To effectively regulate the grain boundary infiltration in CoCrFeMnNi high-entropy alloy(Cantor alloys,HEA)caused by the violent atomic interdiffusion,the higher configuration entropy on Cantor alloys surface was designed and realized via eutectic high-entropy(EHEA)transformation.Meanwhile,to effectively alleviate the residual stress caused by the notable difference in the thermal expansion coefficient(CTE)between Cantor alloys and Zr-3 alloys,a cladding layer was applied to the HEA surface using laser cladding technology of Nb,followed by brazing to Zr-3 alloys with Zr63.2Cu filler.The cladding layer’s microstructure comprised Nbss and FCC+(Co,Ni)_(2) Nb eutectic structure,resulting from an in-situ reaction between Cantor alloys and Nb.The Nbss and FCC demonstrated good plasticity,and the(Co,Ni)_(2) Nb Laves phase provided increased strength,endowing both good plastic deformation ability and strength of the cladding layer.Notably,the existence of EHEA in the laser cladding layer made the Cantor alloy entropy from 1.61 R to 1.77 R,greatly enhancing its thermal stability and suppressing the grave grain boundary infiltration.Joints produced via laser cladding with Nb-assisted brazing exhibited a complex microstructure(HEA/Nbss+FCC+(Co,Ni)_(2)Nb/(Zr,Nb)(Cr,Mn)_(2)+(Zr,Nb)ss/(Zr,Nb)_(2)(Cu,Ni,Co,Fe)+(Zr,Nb)(Cr,Mn)_(2)+(Zr,Nb)ss/Zr-3) and a significantly improved shear strength of 242.8 MPa at 1010℃ for 10 min,42.4%higher than that of directly brazed joints.This improvement was attributed to reduced grain boundary infiltration,alleviated residual stress due to CTE disparity,and eliminated micro-cracks in the brazing seam.This study presents an effective solution for reducing residual stresses and achieving reliable bonding between Cantor alloys and Zr-3 alloys,with potential applications in brazing CoCrFeNi-based HEA and Zr-3 due to the beneficial eutectic reaction between CoCrFeNi and Nb.
基金financially supported by the Natural Science Basic Research Program of Shaanxi Province,China(No.2023-JC-QN-0581)Advanced Power Specialty,China(No.YK22C-9)。
文摘The microstructure evolution and strengthening mechanism of WE54 alloy with different hard-plate rolling(HPR)processes were systematically investigated.The results suggest that the mechanical properties of the as-rolled alloys are significantly enhanced compared to those of the as-cast alloy.When subjected to three rolling passes at 450℃ and 490℃,grain refinement occurs due to dynamic recrystallization.A mixed-grain structure is formed after a single pass rolling with a substantial reduction(65%)at 490℃.The dynamic recrystallization(DRX)mechanism of the alloy during the HPR includes continuous dynamic recrystallization(CDRX),discontinuous dynamic recrystallization(DDRX),and twin-induced recrystallization(TDRX).The WE54 alloy exhibits the highest strength after three passes of HPR at 450℃,with tensile strength and yield strength of 374 and 323 MPa,respectively.The significant improvement in the mechanical properties of the alloy is primarily attributed to fine-grain strengthening,solid solution strengthening,and dislocation strengthening.
基金supported by the National Natural Science Foundation of China(Grant No.U2341254)the National Natural Science Foundation of China(Grant No.52071124),the Natural Science Foundation of Jiangsu Province(No.BK20230502)the Jiangsu Funding Program for Excellent Postdoctoral Talent(No.2022ZB547).
文摘The unique structure and formation mechanism of medium-entropy alloys(MEAs)generally result in bet-ter comprehensive properties than traditional alloys.However,the strength-ductility trade-offremains a bottleneck,which limits their applications.In this study,we designed novel high-performance CrNiCu x MEAs with a heterophase composition by incorporating a Cu-rich phase,and they were fabricated using laser-directed energy deposition(LDED).The results show that synergistic strengthening from multiple phases significantly improved the mechanical properties of the alloys,resulting in a tensile strength of 675 MPa and a ductility of 34.4%,demonstrating an excellent combination of high tensile strength and ductility.The improved mechanical properties of the CrNiCu x medium-entropy alloys are primarily due to the heterophase interfacial strengthening mechanism.In the alloy,numerous semi-coherent and coher-ent interfaces formed between the Cr-rich phase,Cu-rich phase,and the matrix,creating extensive lattice distortions at the interfaces.An increase in the Cu-rich phase content promoted the interaction between phases,enhancing the strain energy of the alloy and the barrier strength of the interfaces.The calcu-latedτint values,ranging from approximately 5.92-6.69 GPa,are significantly higher than those found in traditional alloys,providing a benchmark for designing new high-performance medium-entropy alloys.
基金supported by the National Natural Science Foundation of China(Nos.52301058 and 52271034)the China Postdoctoral Science Foundation(No.2023M732183)+3 种基金the Postdoctoral Fellowship Program of CPSF(No.GZB20230399)the Key scientific and technological project in Ningbo City(No.2022Z056)supported by the Independent Research Project of State Key Laboratory of the Advanced Special Steel,Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS 2023-Z12)the Science and Technology Commission of Shanghai Municipality(No.19DZ2270200).
文摘Fe-28Mn-(10-12)Al-(0.8-1.4)C(wt.%)steels were designed to investigate the influence of varying Al and C content on precipitation behavior ofκ-carbide and its contribution to the strength of high-Mn low-density steels.Results reveal that both Al and C elements promoteκ-carbide precipitation,with C having a more pronounced effect.In near-rapidly solidified 10Al steel strips,increasing C content from 0.8wt.%to 1.4wt.%raises theκ-carbide size from 9.6 nm to 38.2 nm,accompanied by volume fraction increase from 10.2vol.%to 29.8vol.%.In comparison,the average size and volume fraction ofκ-carbides in 12Al0.8C steel are only 11.4 nm and 17.8vol.%,respectively.Higher Al and C content reduces the lattice mismatch between austenite andκ-carbides,thus promoting nucleation ofκ-carbides.Notably,the increase in C content results in a greater reduction in the Gibbs free energy ofκ-carbide,leading to a stronger driving force forκ-carbide formation.Consequently,as the C content increases from 0.8wt.%to 1.4wt.%,the interaction betweenκ-carbides and dislocations transforms from particle cutting to bypassing,and the maximum precipitation strengthening ofκ-carbides reaches 583 MPa.The construction of the relationship between Al and C content andκ-carbide precipitation in this study would provide valuable insights for alloy design of high-Mn steels.
基金Supported by the National Key Research and Development Project,Clinical Study on the Treatment of Refractory Membranous Nephropathy with the Treatment of Strengthening Spleen and Draining Dampness in Method using Single Group Target Value Method(No.2019YFC1709403)Systematic Study on the Diagnosis and Treatment Rules of Membranous Nephropathy in Traditional Chinese Medicine(No.2023YFC35033501,No.2023YFC35033503)。
文摘OBJECTIVE:To evaluate the 10-year therapeutic efficacy of Traditional Chinese Medicine(TCM)using the Strengthening Spleen and Draining Dampness therapy in the management of idiopathic membranous nephropathy(IMN).METHODS:A single-center,retrospective analysis was conducted on patients diagnosed with IMN who met predefined inclusion and exclusion criteria.Data were collected from the Department of Nephrology at Longhua Hospital,affiliated with Shanghai University of Traditional Chinese Medicine,between January 2007 and December 2011.Clinical parameters including 24-h urinary protein,serum albumin,serum creatinine,and estimated glomerular filtration rate(e GFR,EPI)were assessed at baseline and at 1,3,5,and 10 years of follow-up.The efficacy of the Strengthening Spleen and Draining Dampness therapy was analyzed using repeated measures analysis of variance(ANOVA).Kaplan-Meier survival curves and multivariate proportional hazards model(Cox regression models)were employed to identify factors associated with treatment outcomes.RESULTS:A total of 265 patients were included,with a median follow-up duration of 96 months(36,122).TCM treatment significantly reduced 24-h urinary protein levels(P<0.001),and increased serum albumin levels(P<0.001),while serum creatinine remained stable(P=0.187).Remission rates at 1,3,5,and 10 years were 52.81%,69.71%,68.39%,and 72.36%,respectively,and the rates of avoiding composite outcome events at the same intervals were 98.27%,94.29%,94.19%,and 93.50%.In the subgroup receiving TCM only,remission rates were 56.67%,84.44%,76.32%,and 82.86%.For patients treated initially with Western Medicine followed by TCM,the rates were 52.83%,65.85%,67.47%and 67.75%.In the cohort of patients who received TCM as their first-line therapy,remission rates were 49.23%,62.50%,61.76%,and 69.23%.Multivariate Cox regression analysis revealed that the duration of TCM treatment[hazard ratio(HR)=0.826,95%confidence interval(CI)(0.779,0.876),P<0.001],presence of hypertension[HR=1.912,95%CI(1.181,3.094),P=0.008],baseline serum albumin level[HR=0.930,95%CI(0.894,0.969),P<0.001],and the rate of serum albumin increase within the first year of treatment[HR=0.930,95%CI(0.909,0.957),P<0.001]were significantly associated with clinical outcomes.CONCLUSION:The Strengthening Spleen and Draining Dampness therapy demonstrated robust short-and longterm efficacy in treating IMN,with high rates of remission and renal survival over 10 years.Key factors influencing clinical remission included the duration of TCM treatment,baseline serum albumin levels,the presence of hypertension,and the rate of increase in serum albumin within the first year.These findings suggest that this TCM approach provides a viable long-term treatment option for IMN.
基金supported by the National Natural Science Foundation of China(Nos.52122408 and 52071023)financial support from the Fundamental Research Funds for the Central Universities(University of Science and Technology Beijing,No.FRF-TP-2021-04C1,and 06500135)。
文摘Martensite is an important microstructure in ultrahigh-strength steels,and enhancing the strength of martensitic steels often involves the introduction of precipitated phases within the martensitic matrix.Despite considerable research efforts devoted to this area,a systematic summary of these advancements is lacking.This review focuses on the precipitates prevalent in ultrahigh-strength martensitic steel,primarily carbides(e.g.,MC,M_(2)C,and M_(3)C)and intermetallic compounds(e.g.,Ni Al,Ni_(3)X,and Fe_(2)Mo).The precipitation-strengthening effect of these precipitates on ultrahigh-strength martensitic steel is discussed from the aspects of heat treatment processes,microstructure of precipitate-strengthened martensite matrix,and mechanical performance.Finally,a perspective on the development of precipitation-strengthened martensitic steel is presented to contribute to the advancement of ultrahigh-strength martensitic steel.This review highlights significant findings,ongoing challenges,and opportunities in the development of ultrahigh-strength martensitic steel.
基金National Key Research and Development Program of China(2022YFE03140002,2019YFE03110200)National Natural Science Foundation of China(52273320,52173303,52325103,52171084)+2 种基金Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0470000)Anhui Provincial Natural Science Foundation(2308085J07)HFIPS Director's Fund(YZJJ202102,YZJJQY202306,YZJJKX202202)。
文摘93W-4.9Ni-2.1Fe alloys strengthened by nanoscale ZrC particles were prepared by spark-plasma-sintering(SPS)and hot rotary swaging,separately.Results show that the addition of a small number of ZrC nanoparticles can refine grains and increase the hardness of the WNiFe alloys,but hinder the formation of theγ-(Ni,Fe)phase during SPS.SPSed WNiFe and WNiFe-ZrC alloys are brittle at room temperature,while the swaged WNiFe and WNiFe-0.5ZrC(wt%)alloys are ductile.At 400°C,the swaged WNiFe-0.5ZrC alloy exhibits both higher tensile strength and better ductility than the swaged WNiFe.The nanoscale particles distributed in the W grains andγ-(Ni,Fe)phase provide a good pinning effect,which enhances the strength.The thermal conductivity of swaged WNiFe-0.5ZrC is only 71 W·m^(-1)·K^(-1)at room temperature,but it increases to about 100 W·m^(-1)·K^(-1)at 800°C,which is close to that of pure W(121 W·m^(-1)·K^(-1)).These results show the potential of WNiFe alloys as plasma-facing materials in fusion reactor.
基金Foundation of Northwest Institute for Nonferrous Metal Research(ZZXJ2203)Capital Projects of Financial Department of Shaanxi Province(YK22C-12)+3 种基金Innovation Capability Support Plan in Shaanxi Province(2023KJXX-083)Key Research and Development Projects of Shaanxi Province(2024GXYBXM-351,2024GX-YBXM-356)National Natural Science Foundation of China(62204207,12204383)Xi'an Postdoctoral Innovation Base Funding Program。
文摘The extraordinary strength of metal/graphene composites is significantly determined by the characteristic size,distribution and morphology of graphene.However,the effect of the graphene size/distribution on the mechanical properties and related strengthening mechanisms has not been fully elucidated.Herein,under the same volume fraction and distribution conditions of graphene,molecular dynamics simulations were used to investigate the effect of graphene sheet size on the hardness and deformation behavior of Cu/graphene composites under complex stress field.Two models of pure single crystalline Cu and graphene fully covered Cu matrix composite were constructed for comparison.The results show that the strengthening effect changes with varying the graphene sheet size.Besides the graphene dislocation blocking effect and the load-bearing effect,the deformation mechanisms change from stacking fault tetrahedron,dislocation bypassing and dislocation cutting to dislocation nucleation in turn with decreasing the graphene sheet size.The hardness of Cu/graphene composite,with the graphene sheet not completely covering the metal matrix,can even be higher than that of the fully covered composite.The extra strengthening mechanisms of dislocation bypassing mechanism and the stacking fault tetrahedra pinning dislocation mechanism contribute to the increase in hardness.
