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Improved expert system of rockburst intensity level prediction based on machine learning and data-driven:Supported by 1114 rockburst cases in 197 rock underground projects
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作者 PANG Hong-li GONG Feng-qiang +1 位作者 GAO Ming-zhong DAI Jin-hao 《Journal of Central South University》 2026年第1期335-356,共22页
Accurate prediction of rockburst intensity levels is crucial for ensuring the safety of deep hard rock engineering construction.This paper introduced an expert system for rockburst intensity level prediction that empl... Accurate prediction of rockburst intensity levels is crucial for ensuring the safety of deep hard rock engineering construction.This paper introduced an expert system for rockburst intensity level prediction that employs machine learning algorithms as the basis for its inference rules.The system comprises four modules:a database,a repository,an inference engine,and an interpreter.A database containing 1114 rockburst cases was used to construct 357 datasets that serve as the repository for the expert system.Additionally,19 types of machine learning algorithms were used to establish 6783 micro-models to construct cognitive rules within the inference engine.By integrating probability theory and marginal analysis,a fuzzy scoring method based on the SoftMax function was developed and applied to the interpreter for rockburst intensity level prediction,effectively restoring the continuity of rockburst characteristics.The research results indicate that ensemble algorithms based on decision trees are more effective in capturing the characteristics of rockburst.Key factors for accurate prediction of rockburst intensity include uniaxial compressive strength,elastic energy index,the maximum principal stress,tangential stress,and their composite indicators.The accuracy of the proposed rockburst intensity level prediction expert system was verified using 20 engineering rockburst cases,with predictions aligning closely with the actual rockburst intensity levels. 展开更多
关键词 rock mechanics rockBURST rockburst intensity level prediction expert system machine learning supervised learning
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Energy relief effect of real-time drilling to prevent rockburst in high-stress rock
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作者 Zhichao He Fengqiang Gong +2 位作者 Li Ren Weimin Yang Xuezhen Wu 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第2期1460-1475,共16页
To investigate the energy relief effect of real-time drilling in preventing rockburst in high-stress rock,a series of high-stress real-time drilling uniaxial compression tests were conducted on red sandstone specimens... To investigate the energy relief effect of real-time drilling in preventing rockburst in high-stress rock,a series of high-stress real-time drilling uniaxial compression tests were conducted on red sandstone specimens using the SG4500 drilling rig.Results showed that the mechanical behavior(i.e.peak strength and rockburst intensity)of the rock was weakened under high-stress real-time drilling and exhibited a downward trend as the drilling diameter increased.The real-time drilling energy dissipation index(ERD)was proposed to characterize the energy relief during high-stress real-time drilling.The ERD exhibited a linear increase with the real-time drilling diameter.Furthermore,the elastic strain energy of post-drilling rock showed a linear relationship with the square of stress across different stress levels,which also applied to the peak elastic strain energy and the square of peak stress.This findingreveals the intrinsic link between the weakening effect of peak elastic strain energy and peak strength due to high-stress real-time drilling,confirmingthe consistency between energy relief and pressure relief effects.By establishing relationships among rockburst proneness,peak elastic strain energy,and peak strength,it was demonstrated that high-stress real-time drilling reduces rockburst proneness through energy dissipation.Specifically,both peak elastic strain energy and rockburst proneness decreased with larger drill bit diameters,consistent with reductions in peak strength,rockburst intensity,and fractal dimensions of high-stress real-time drilled rock.These results validate the energy relief mechanism of real-time drilling in mitigating rockburst risks. 展开更多
关键词 rock mechanics rockBURST Real-time drilling Drilling energy relief Energy storage capacity rockburst proneness
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血根碱调节RhoA/ROCK信号通路对糖尿病性骨质疏松症大鼠骨代谢和炎性损伤的影响
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作者 周飞 易松 +1 位作者 岳建彪 张上上 《免疫学杂志》 2026年第2期81-86,共6页
目的探究血根碱调节Ras同源基因家族成员A(RhoA)/Rho相关激酶(ROCK)信号通路对糖尿病性骨质疏松症大鼠骨代谢和炎性损伤的影响。方法取60只健康雄性8周龄SD大鼠,分为正常组(未予任何处理)、模型组(腹腔注射60 mg/kg 0.2%链脲佐菌素+骨... 目的探究血根碱调节Ras同源基因家族成员A(RhoA)/Rho相关激酶(ROCK)信号通路对糖尿病性骨质疏松症大鼠骨代谢和炎性损伤的影响。方法取60只健康雄性8周龄SD大鼠,分为正常组(未予任何处理)、模型组(腹腔注射60 mg/kg 0.2%链脲佐菌素+骨密度降低)、低剂量血根碱组(L-血根碱组)、高剂量血根碱组(H-血根碱组)、H-血根碱+抑制剂组,每组12只,L-血根碱组、H-血根碱组和H-血根碱+抑制剂组分别为造模成功大鼠予2.50 mg/(kg·d)血根碱灌胃+等量0.9%氯化钠注射液腹腔注射、6.25 mg/(kg·d)血根碱灌胃+等量0.9%氯化钠注射液腹腔注射、6.25 mg/(kg·d)血根碱灌胃+40 mg/(kg·d)Rhosin腹腔注射。各组大鼠处理8周后,使用双能X线吸收测定扫描系统测量骨密度;检测血清钙、骨钙素(OC)、骨保护素(OPG)、碱性磷酸酶(ALP)水平;行生物力学测试检测各组大鼠股骨最大载荷;HE染色观察各组大鼠胰腺组织病理学变化与股骨组织形态学;酶联免疫吸附试验检测各组大鼠血清肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)水平;Western blot实验检测各组大鼠股骨组织RhoA、ROCK1和ROCK2蛋白表达。结果与正常组相比,模型组大鼠骨密度和股骨最大载荷降低,胰岛和股骨组织被破坏,血清钙、OC、OPG含量及股骨组织RhoA、ROCK1、ROCK2蛋白表达降低,血清ALP、IL-1β、TNF-α、IL-6水平升高(P<0.05);与模型组相比,L-血根碱组、H-血根碱组大鼠骨密度和股骨最大载荷升高,胰岛和股骨组织损伤减轻,血清钙、OC、OPG含量及股骨组织RhoA、ROCK1、ROCK2蛋白表达升高,血清ALP、IL-1β、TNF-α、IL-6水平降低,且H-血根碱组上述指标变化更显著(P<0.05);与H-血根碱组相比,H-血根碱+抑制剂组逆转了血根碱对大鼠骨代谢和炎性损伤的影响。结论血根碱通过激活RhoA/ROCK信号通路改善糖尿病性骨质疏松症大鼠骨代谢,并减轻了其炎性损伤。 展开更多
关键词 骨质疏松症 糖尿病性 血根碱 大鼠 RhoA/rock信号通路 骨代谢 炎性损伤
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Early Warning of Rock Collapse Based on Precursor Identification in the Detachment Phase
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作者 Yan Du Mengjia Lyu +4 位作者 Mowen Xie Yujing Jiang Santos Daniel Chicas Hongda Zhang Jingnan Liu 《Journal of Earth Science》 2026年第1期373-380,共8页
0 INTRODUCTION Due to the sudden and highly destructive nature of slope rock collapse,developing effective early warning systems has become an urgent challenge in geotechnical engineering(Cai and Detournay,2024;Loew e... 0 INTRODUCTION Due to the sudden and highly destructive nature of slope rock collapse,developing effective early warning systems has become an urgent challenge in geotechnical engineering(Cai and Detournay,2024;Loew et al.,2017).Traditional monitoring methods primarily target the acceleration stage preceding disasters(such as displacement monitoring for landslides and debris flows),which is effective for early warning of plastic collapse disasters but often inadequate for brittle failure modes(Walter et al.,2019;Chao et al.,2018;Crosta et al.,2017). 展开更多
关键词 precursor identification monitoring methods displacement monitoring geotechnical engineering cai early warning detachment phase slope rock collapsedeveloping rock collapse
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Fragmentation characteristics and mechanical response of hard rock indented by cutting picks:Effects of confinement,spacing,and pre-grooving
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作者 Pingkuang Luo Diyuan Li +1 位作者 Hiroyuki Noda Ruiyuan Li 《International Journal of Mining Science and Technology》 2026年第3期615-633,共19页
Efficient hard-rock fragmentation remains a critical challenge in mechanized mining.This study designed an adjustable-spacing mold and conducted double cutting pick indentation tests on granite.Mechanical responses an... Efficient hard-rock fragmentation remains a critical challenge in mechanized mining.This study designed an adjustable-spacing mold and conducted double cutting pick indentation tests on granite.Mechanical responses and fragmentation characteristics under varying horizontal stresses,pick spacings,and groove depths were systematically analyzed.Unidirectional stress concentration altered the rock fragmentation modes,exhibiting a dual effect on the fragmentation process.The maximum indentation force(F_(max)),indentation hardness index(IHI),indentation modulus(IM),and indentation energy(W)initially increased and then decreased with rising horizontal stress.Appropriate spacing promoted radial crack coalescence,whereas too small a spacing(20 mm)caused repetitive re-fragmentation of rock chips,and too large a spacing(50 mm)resulted in unbroken ridges.Pre-cut grooves weakened the rock,reducing F_(max) and specific energy(SE),thus improving fragmentation efficiency,although the improvement slowed beyond a 10-mm groove depth.Based on the results and rock-mass conditioning assisted fragmentation mechanism,a“stress-structure dual control”assisted fragmentation mechanism was proposed,and a“pre-drilling unloading−alternate stopping”mining scheme was exploratorily designed.This approach creates favorable conditions for rock fragmentation by reducing stress levels and rock mass integrity in target zones,providing theoretical support and an engineering paradigm for mecheanized mining of deep resources. 展开更多
关键词 Hard rock fragmentation Indentation tests Cutting pick rock mass conditioning Mechanized mining scheme
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Effect of high-frequency microseismicity on shear strength of interlayer structural planes of bedding rock landslides
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作者 Shan Dong Xi Hu +2 位作者 Tingting Shi Qihua Zhang Zhijie Mai 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第3期1719-1735,共17页
Water storage in the Three Gorges Reservoir in China has increased the regional microseismicity.Bedding-rock landslides,one of the most common slope structures in the Three Gorges Reservoir,are highly prone to sliding... Water storage in the Three Gorges Reservoir in China has increased the regional microseismicity.Bedding-rock landslides,one of the most common slope structures in the Three Gorges Reservoir,are highly prone to sliding under seismic loading.Existing research primarily focuses on the stability of bedding rock landslides under strong earthquakes,while studies on the cumulative damage and long-term stability of bedding rock landslides under high-frequency microseismicity remain immature.In this study,we considered bedding rock landslides under high-frequency microseismicity in the Three Gorges Reservoir area as the research subject and equivalent microseismicity as pre-peak cyclic loading.First,we analyzed the shear strength deterioration of rock mass structural planes under pre-peak cyclic loading conditions and found that the deformation and failure of structural planes involve contact and damage effects.The shear strength of the rock mass structural planes under pre-peak cyclic loading conditions is affected by the confining pressure,loading rate,loading amplitude,and number of loading cycles.Among these factors,the shear strength of the structural planes was the most sensitive to the number of loading cycles.As the number of cycles increased,the rock mass structural planes underwent three stages:stress adjustment(increase in shear strength),fatigue damage(gradual decrease in shear strength),and structural failure(rapid decrease in shear strength).The stability of bedding rock landslides under high-frequency microseismicity was analyzed,revealing that the stability of bedding rock landslides under high-frequency microseismicity can be divided into three stages:short-term enhancement,gradual degradation,and rapid deterioration,exhibiting characteristics of gradual and sudden changes. 展开更多
关键词 High-frequency microseismicity rock mass structural plane Shear strength deterioration Bedding rock landslides Stability analysis
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RhoA/ROCK信号通路在椎间盘退变中的作用
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作者 杜健强 郭子煜 +3 位作者 姚晨阳 冯其金 古恩鹏 王琳珏 《生理科学进展》 北大核心 2026年第1期52-59,共8页
椎间盘由髓核、纤维环和软骨终板组成,对维持脊柱正常生理功能至关重要。椎间盘退变(intervertebral disc degeneration,IDD)是导致腰背痛等脊柱退行性疾病的主要病理基础,给人们的健康状况造成极大的困扰。然而目前对IDD的分子机制仍... 椎间盘由髓核、纤维环和软骨终板组成,对维持脊柱正常生理功能至关重要。椎间盘退变(intervertebral disc degeneration,IDD)是导致腰背痛等脊柱退行性疾病的主要病理基础,给人们的健康状况造成极大的困扰。然而目前对IDD的分子机制仍然缺乏清晰的了解,导致缺乏有效的靶向干预措施。RAS同源家族成员A(RAS homolog family member A,RhoA)/Rho相关蛋白激酶(Rho-associated protein kinase,ROCK)信号通路是调节细胞收缩、迁移和生长的经典通路。其被激活后可参与调控细胞骨架重塑、细胞外基质代谢、生物钟节律、细胞表型改变、细胞衰老及死亡等环节,进而影响IDD的病理进程。深入探究RhoA/ROCK信号通路在IDD中的作用,不仅能揭示疾病发生的分子生物学机制,也有望为研发靶向该通路的治疗策略提供理论依据。 展开更多
关键词 椎间盘退变 RhoA/rock 信号传导 作用机制
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温阳利水方通过激活RhoA/ROCK通路改善慢性肺源性心脏病小鼠心肌细胞焦亡的机制
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作者 陈昕芳 李红 +2 位作者 苏士成 吴峰妹 黄辉 《辽宁中医杂志》 北大核心 2026年第2期204-208,F0003,共6页
目的探讨温阳利水方通过激活RhoA/ROCK通路改善慢性肺源性心脏病小鼠心肌细胞焦亡的机制。方法60只健康雄性C57BL/6小鼠用于实验研究。将小鼠暴露于烟雾和高压氧舱中诱导慢性肺源性心脏病(chronic pulmonary heart disease,CPHD)模型。... 目的探讨温阳利水方通过激活RhoA/ROCK通路改善慢性肺源性心脏病小鼠心肌细胞焦亡的机制。方法60只健康雄性C57BL/6小鼠用于实验研究。将小鼠暴露于烟雾和高压氧舱中诱导慢性肺源性心脏病(chronic pulmonary heart disease,CPHD)模型。将小鼠分为以下3组:对照组(正常条件下饲养的小鼠,接受清洁空气和0.9%氯化钠溶液作为模型组和温阳利水方组的对照,n=20),模型组(如前所述建立的CPF模型,n=20),温阳利水方组(在模型小鼠的基础上给予温阳利水方药剂治疗,n=20)。通过qPCR分析RhoA、ROCK1和ROCK2 mRNA表达。通过蛋白质印迹分析小鼠心肌组织p-MBS/t-MBS比值。通过酶联免疫吸附测定(ELISA)检测小鼠外周血炎症因子肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、白细胞介素1β(interleukin-1β,IL-1β)和白细胞介素6(interleukin-6,IL-6)水平。组织学分析小鼠心肌受损情况。通过超声心动图检测小鼠心肌功能。通过PI染色检测焦亡细胞。通过蛋白质印迹分析焦亡相关因子高迁移率族蛋白(HMGB1)和热休克蛋白70(HSP70)的表达。结果模型组RhoA、ROCK1和ROCK2 mRNA表达较对照组升高(P<0.05),温阳利水方组RhoA、ROCK1和ROCK2 mRNA表达较模型组降低(P<0.05)。模型组p-MBS/t-MBS比值较对照组升高(P<0.05),温阳利水方组p-MBS/t-MBS比值较模型组降低(P<0.05)。模型组TNF-α、IL-1β和IL-6水平较对照组升高(P<0.05),温阳利水方组TNF-α、IL-1β和IL-6水平较模型组降低(P<0.05)。HE染色显示,与对照组小鼠心肌相比,模型组小鼠心肌细胞排列紊乱,细胞肥大,炎症细胞浸润明显(P<0.05),与模型组相比,温阳利水方显著改善了CPHD引起的病理改变(P<0.05)。马松染色作为纤维化的病理检查表明,CPHD可导致小鼠严重的心肌纤维化,温阳利水方治疗可显著减少胶原沉积(P<0.05)。模型组小鼠左室收缩压(left ventricular systolic pressure,LVSP)、左室射血分数(left ventricular ejection fraction,LVEF)和心搏量(stroke volume,SV)较对照组降低(P<0.05),温阳利水方组LVSP、LVEF和SV较模型组升高(P<0.05)。模型组小鼠心肌细胞焦亡率较对照组升高(P<0.05),温阳利水方组小鼠心肌细胞焦亡率较模型组降低(P<0.05)。模型组HMGB1和HSP70的表达较对照组升高(P<0.05),温阳利水方组HMGB1和HSP70的蛋白表达较模型组降低(P<0.05)。结论温阳利水方通过激活RhoA/ROCK通路,显著改善了CPHD小鼠模型中心肌细胞焦亡和心肌结构及功能。 展开更多
关键词 温阳利水方 RhoA/rock CPHD 心肌细胞焦亡
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基于RhoA/ROCKⅡ通路探讨水蛭改善脑缺血/再灌注小鼠脑损伤的机制
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作者 赵磊 曹玉爽 +4 位作者 郭莉琛 柴丽娟 王少峡 袁庆 胡利民 《中国药理学通报》 北大核心 2026年第1期100-106,共7页
目的探究水蛭提取物(leech)调控Rho激酶(Rhoassociated coiled-coil-forming kinase,ROCK)通路保护大脑中动脉闭塞/再灌注(middle cerebral artery occlusion/reperfu-sion,MCAO/R)小鼠血脑屏障及其作用机制。方法采用大脑中动脉线栓法... 目的探究水蛭提取物(leech)调控Rho激酶(Rhoassociated coiled-coil-forming kinase,ROCK)通路保护大脑中动脉闭塞/再灌注(middle cerebral artery occlusion/reperfu-sion,MCAO/R)小鼠血脑屏障及其作用机制。方法采用大脑中动脉线栓法建立MCAO/R模型后,将SPF级C57BL/6(C57BL/6JNifdc)雄性小鼠,分为假手术(Sham)组、MCAO/R组、阿司匹林组(aspirin,13 mg·kg^(-1))、水蛭提取液组(leech,0.8、1.6、2.4 mL·kg^(-1))共6组。TTC染色观察脑梗死体积,mNSS评分评价神经缺损情况;HE染色及Nissl染色观察各组小鼠脑缺血半暗带病理改变;免疫荧光检测Laminin,PDGFRβ/Biotinylated LEL免疫荧光双染检测脑缺血半暗带周细胞与脑微血管内皮细胞解离情况;Western blot检测RhoA、ROCKⅡ蛋白,紧密连接相关蛋白ZO-1、Occludin、Clau-din-5,基底膜(BM)相关蛋白层粘连蛋白(LN)、纤维连接蛋白(FN)及金属基质蛋白酶MMP-2、MMP-9蛋白,以及p-MLC/MLC蛋白表达情况。结果Leech明显改善小鼠神经缺损,减轻脑梗死体积(P<0.05,P<0.01);Western blot结果显示,leech可上调ZO-1、Occludin、Claudin-5、Laminin、Fibronectin蛋白表达,降低p-MLC/MLC、RhoA、ROCKⅡ、MMP-2、MMP-9蛋白表达(P<0.05,P<0.01);免疫荧光结果显示,leech可明显提高Laminin及PDGFRβ/Biotinylated LEL免疫荧光双染的表达。结论Leech可以改善MCAO/R小鼠脑缺血半暗带BBB损伤,其机制可能是通过调节RhoA/ROCKⅡ信号通路有关。 展开更多
关键词 水蛭 脑缺血/再灌注损伤 RhoA/rockⅡ信号通路 血脑屏障 紧密连接 基质金属蛋白酶
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FOXK1通过上调ROCK1表达促进食管鳞状细胞癌的恶性生物学行为
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作者 武俊红 杨霞 +4 位作者 许环琛 王歆皓 胡照坤 路军涛 郭炜 《临床与实验病理学杂志》 北大核心 2026年第1期29-37,共9页
目的探讨FOXK1在食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)中的表达、功能及其潜在的分子调控机制。方法常规培养ESCC细胞系KYSE-150、KYSE-170和TE-1;并使用转染试剂将核酸和质粒转染至各组细胞。结合数据库分析和qRT-... 目的探讨FOXK1在食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)中的表达、功能及其潜在的分子调控机制。方法常规培养ESCC细胞系KYSE-150、KYSE-170和TE-1;并使用转染试剂将核酸和质粒转染至各组细胞。结合数据库分析和qRT-PCR检测FOXK1在ESCC组织和细胞中的表达;开展生物信息学分析预测下游靶基因,并以ROCK1为候选基因,采用qRT-PCR检测其表达,双荧光素酶报告实验验证FOXK1对ROCK1启动子的转录调控作用。通过平板克隆实验、划痕愈合实验及Transwell小室实验检测各组细胞的克隆形成、迁移及侵袭能力。应用qRT-PCR和Western blot法检测各组细胞中上皮-间质转化(epithelialmesenchymal transition,EMT)关键分子的表达;免疫荧光实验检测F-actin的荧光强度。结果FOXK1在ESCC组织和细胞中呈高表达,其中KYSE-150、KYSE-170和TE-1细胞的表达量分别约为正常食管上皮细胞的40.0倍、17.9倍和24.8倍(P<0.05)。ROCK1为FOXK1的潜在下游靶基因,两者表达水平呈正相关(P<0.05),且ROCK1在ESCC细胞系中亦高表达。过表达及敲低FOXK1会相应上调或下调ROCK1的表达,并证实FOXK1可结合ROCK1启动子发挥转录调控作用。功能方面,过表达FOXK1促进ESCC细胞增殖、迁移和侵袭,敲低ROCK1抑制上述表型,两者同时作用可部分逆转由FOXK1过表达所引起的促肿瘤效应。机制层面,敲低ROCK1使EMT进程关键分子CDH2、vimentin和ZEB1的mRNA及蛋白水平均下降;过表达FOXK1增强F-actin的聚合,敲低ROCK1削弱F-actin的聚合,两者同时作用可部分逆转FOXK1对F-actin的促聚合效应。结论FOXK1通过上调ROCK1的表达促进ESCC细胞的迁移和侵袭,提示FOXK1可能作为ESCC的潜在诊断和治疗靶点。 展开更多
关键词 食管肿瘤 鳞状细胞癌 FOXK1 rock1 上皮-间质转化 细胞骨架
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Zircon U-Pb ages of the volcanic rocks and their constraints on the ending of the Huoshiling Formation in the southeastern of Songliao Basin,NE China 被引量:1
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作者 Xue-jiao Qu Ming-kai Zhang +5 位作者 Pu-jun Wang Zhuo-long Yang You-feng Gao Kang-jun Wu Jia Wang Xian-feng Tan 《China Geology》 2026年第1期214-216,I0023,共4页
1.Objective The Songliao Basin(SB)is situated on the eastern margin of Eurasia continent(Northeast Asia).During the Late Jurassic to Early Cretaceous,hundreds of rifting basins developed in this area,and the SB is a u... 1.Objective The Songliao Basin(SB)is situated on the eastern margin of Eurasia continent(Northeast Asia).During the Late Jurassic to Early Cretaceous,hundreds of rifting basins developed in this area,and the SB is a unique case among them as it evolved into the largest rift basin.The rift basin filling of SB includes Huoshiling Formation,Shahezi Formation,and Yingcheng Formation in ascending order.The mega-rifting was controlled by the Mongol-Okhotsk Collisional Belt to the north and northwest and the Pacific Subduction Zone to the east(Wang PJ et al.,2016).As the first rifting succession,the Huoshiling Formation contains key information about the formation of the rifting basins and records the evolution of the Mongol-Okhotsk Collisional Belt and the Pacific Subduction Zone.However,the geological period of the Huoshiling Formation has not been well constrained for two main reasons.First,it is easily confused with the Yingcheng Formation,as both are dominated by volcanogenic-sedimentary successions.Second,there is lack of reliable dating samples from the uppermost part of the Huoshiling Formation due to its considerable burial depth. 展开更多
关键词 rift basin rift basinthe yingcheng formation ZIRCON U Pb ages rifting basins volcanic rocks huoshiling formationshahezi formationand
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Quantitative principles of dynamic interaction between rock support and surrounding rock in rockburst roadways 被引量:6
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作者 Lianpeng Dai Dingjie Feng +4 位作者 Yishan Pan Aiwen Wang Ying Ma Yonghui Xiao Jianzhuo Zhang 《International Journal of Mining Science and Technology》 2025年第1期41-55,共15页
Rockbursts, which mainly affect mining roadways, are dynamic disasters arising from the surrounding rock under high stress. Understanding the interaction between supports and the surrounding rock is necessary for effe... Rockbursts, which mainly affect mining roadways, are dynamic disasters arising from the surrounding rock under high stress. Understanding the interaction between supports and the surrounding rock is necessary for effective rockburst control. In this study, the squeezing behavior of the surrounding rock is analyzed in rockburst roadways, and a mechanical model of rockbursts is established considering the dynamic support stress, thus deriving formulas and providing characteristic curves for describing the interaction between the support and surrounding rock. Design principles and parameters of supports for rockburst control are proposed. The results show that only when the geostress magnitude exceeds a critical value can it drive the formation of rockburst conditions. The main factors influencing the convergence response and rockburst occurrence around roadways are geostress, rock brittleness, uniaxial compressive strength, and roadway excavation size. Roadway support devices can play a role in controlling rockburst by suppressing the squeezing evolution of the surrounding rock towards instability points of rockburst. Further, the higher the strength and the longer the impact stroke of support devices with constant resistance, the more easily multiple balance points can be formed with the surrounding rock to control rockburst occurrence. Supports with long impact stroke allow adaptation to varying geostress levels around the roadway, aiding in rockburst control. The results offer a quantitative method for designing support systems for rockburst-prone roadways. The design criterion of supports is determined by the intersection between the convergence curve of the surrounding rock and the squeezing deformation curve of the support devices. 展开更多
关键词 Deep roadway rockBURST Dynamic interaction rock support Surrounding rock rockburst control
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基于RhoA/ROCK1通路探讨花旗松素对缺氧/复氧诱导的心肌细胞损伤的影响
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作者 徐颖 李丽华 +1 位作者 刘晨 张宁 《河北医学》 2026年第2期240-247,共8页
目的:基于RhoA/ROCK1通路,探讨花旗松素(TAX)对缺氧/复氧(H/R)诱导的心肌细胞损伤的影响。方法:CCK-8筛选TAX处理H/R诱导H9C2的最佳浓度;H9C2细胞分为正常组、H/R组、H/R+TAX组、H/R+ROCK抑制剂(Y-27632)组、H/R+TAX+RhoA激活剂溶血磷脂... 目的:基于RhoA/ROCK1通路,探讨花旗松素(TAX)对缺氧/复氧(H/R)诱导的心肌细胞损伤的影响。方法:CCK-8筛选TAX处理H/R诱导H9C2的最佳浓度;H9C2细胞分为正常组、H/R组、H/R+TAX组、H/R+ROCK抑制剂(Y-27632)组、H/R+TAX+RhoA激活剂溶血磷脂酸(LPA)组。台盼蓝染色检测各组H9C2细胞存活率;试剂盒检测各组H9C2细胞LDH释放率;流式细胞仪和TUENL染色检测各组H9C2细胞凋亡率;DCFH-DA法和ELISA检测各组H9C2细胞氧化应激和炎症反应;Western blot检测各组H9C2细胞RhoA/ROCK1通路相关蛋白表达。结果:与对照组比较,H/R组H9C2细胞存活率明显降低(P<0.05);与H/R组比较,H/R+TAX 20μmoL/L组和H/R+TAX 40μmoL/L组H9C2细胞存活率明显升高(P<0.05);与H/R+TAX 40μmoL/L组比较,H/R+TAX 80μmoL/L组H9C2细胞存活率明显降低(P<0.05)。与对照组比较,H/R组H9C2细胞存活率、GSH-Px下调,LDH释放率、凋亡率以及TUENL阳性细胞数、ROS荧光强度、MDA、NOX4、IL-6、TNF-α、NLRP3、ICAM-1、RhoA、ROCK1、p-MLC2/MLC2上调(P<0.05);与H/R组比较,H/R+TAX组和H/R+Y-27632组H9C2细胞存活率、GSH-Px上调,LDH释放率、凋亡率以及TUENL阳性细胞数、ROS荧光强度、MDA、NOX4、IL-6、TNF-α、NLRP3、ICAM-1、ROCK1、p-MLC2/MLC2下调(P<0.05);与H/R+TAX组比较,H/R+TAX+LPA组H9C2细胞存活率、GSH-Px下调,LDH释放率、凋亡率以及TUENL阳性细胞数、ROS荧光强度、MDA、NOX4、IL-6、TNF-α、NLRP3、ICAM-1、RhoA、ROCK1、p-MLC2/MLC2上调(P<0.05)。结论:TAX通过抑制RhoA/ROCK1通路调控氧化应激、炎症反应和细胞凋亡,缓解H/R诱导的心肌细胞损伤。 展开更多
关键词 花旗松素 缺氧/复氧 心肌细胞 RhoA/rock1通路
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深成侵入岩类不平衡岩石图像数据集PlutonicRocks-13
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作者 陈忠良 胡召齐 郑超杰 《中国科学数据(中英文网络版)》 2026年第1期3-18,共16页
岩性识别是地质工作者的基本技能之一。随着人工智能的兴起,如何把地质专业人员识别岩性的能力转化成人工智能模型,提供岩性智能识别服务,让地学爱好者或者非地质专业人员也能较准确地识别岩性,成为地学领域智能服务需求之一。自然条件... 岩性识别是地质工作者的基本技能之一。随着人工智能的兴起,如何把地质专业人员识别岩性的能力转化成人工智能模型,提供岩性智能识别服务,让地学爱好者或者非地质专业人员也能较准确地识别岩性,成为地学领域智能服务需求之一。自然条件下,由于地表岩石分布不均,岩石图像数据集属于典型的长尾分布。本研究以深成侵入岩为例,选择于炳松等主编的《岩石学》中的岩石分类和命名方案,构建类不平衡的岩石图像识别研究数据集PlutonicRocks-13。本数据集包含13种常见的深成侵入岩,共4785张图片,原始图像共2.49 GB,主要岩石类型包括橄榄岩、辉石岩、角闪石岩、辉长岩、闪长岩、二长岩、正长岩、霞石正长岩、花岗闪长岩、二长花岗岩、正长花岗岩、斜长花岗岩、文象花岗岩。岩石图像主要从野外和馆藏机构采集露头和手标本图像,辅以网络渠道收集。经过筛选、处理和标注后,图像最终形成能为岩石图像分类任务提供基础数据的数据集。同时,采用岩石薄片鉴定和基于深度学习可解释性分析的数据集偏见检测等方法开展数据标注质量控制和评估。采用标注标签转换为问答对的方式,还可构建面向岩石图像分类任务的微调指令,为多模态模型的岩石图像分类任务提供指令微调数据集。本图像数据集可为岩石图像自动识别研究提供可靠的数据支撑,对地质调查、地表基质调查和地质科普等有重要的参考价值。 展开更多
关键词 岩浆岩 侵入岩 长尾分布 类不平衡 图像分类
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A rock physics model-based approach to delineate deep and tight sand reservoir heterogeneity in the Bohai Bay Basin,China
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作者 Donghong Zhou Qifeng Dou +5 位作者 Jiaqi Jiang Yihao Deng Xiaodong Wei Xingrui Dou Yuhui Zhao Fengyang Dong 《Energy Geoscience》 2026年第1期72-80,共9页
Delineating sweet spots is critical for the exploration and production of oil and gas in deep and tight sand reservoirs.The lack of advanced and reliable methods makes this a challenge for geologists and geophysicists... Delineating sweet spots is critical for the exploration and production of oil and gas in deep and tight sand reservoirs.The lack of advanced and reliable methods makes this a challenge for geologists and geophysicists.This study introduces,for the first time,an integrated workflow that combines pre-stack seismic inversion with rock physics modeling to predict reservoir porosity and shale volume(V-shale)for sweet spot identification in tight sand reservoirs.A new elastic parameter,the density calculation index(DCI),is introduced which links acoustic and shear impedance for seismic density inversion,thereby addressing the long-standing problem of poor density inversion accuracy.A novel combined Sun–Walsh rock physics model,developed as part of this study,significantly improves V-shale evaluation from seismic data.The proposed three-step seismic inversion approach includes:(1)deriving acoustic and shear impedance from angle-stack seismic data using model-based inversion;(2)calculating density using shear impedance constrained by DCI,followed by porosity estimation from the density–porosity relation;and(3)evaluating V-shale using theα-parameter derived from the Sun–Walsh model and pre-stack inversion results.This integrated workflow provides an effective tool for building accurate 3D reservoir models,and is especially applicable to deep,low-porosity,tight sand reservoirs worldwide. 展开更多
关键词 rock physics model Seismic inversion Sand reservoir POROSITY V-shale
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An attention module integrated hybrid model for recognizing microseismic signals induced by high-pressure grouting in deep rock layers
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作者 Yongshu Zhang Lianchong Li +2 位作者 Wenqiang Mu Jian Chen Peng Chen 《International Journal of Mining Science and Technology》 2026年第3期595-613,共19页
Microseismic(MS)monitoring is an effective technique to detect mining-induced rock fractures.However,recognizing grouting-induced signals is challenging due to complex geological conditions in deep rock plates.Therefo... Microseismic(MS)monitoring is an effective technique to detect mining-induced rock fractures.However,recognizing grouting-induced signals is challenging due to complex geological conditions in deep rock plates.Therefore,a hybrid model(WM-ResNet50)integrating data enhancement,a deep convolutional neural network(CNN),and convolutional block attention modules(CBAM)was proposed.Firstly,an MS system was established at the Xieqiao coal mine in Anhui Province,China.MS waveforms and injection parameters were acquired during grouting.Secondly,signals were categorized based on time-frequency characteristics to build a dataset,which was divided into training,validation,and test sets at a ratio of 4:1:1.Subsequently,the performance of WM-ResNet50 was evaluated based on indices such as individual precision,total accuracy,recall,and loss function.The results indicated that WMResNet50 achieved an average recognition accuracy of 94.38%,surpassing that of a simple CNN(90.04%),ResNet18(91.72%),and ResNet50(92.48%).Finally,WM-ResNet50 was applied to monitor the whole process at laboratory tests and field cases.Both results affirmed the feasibility and effectiveness of MS inversion in predicting actual slurry diffusion ranges within deep rock layers.By comparison,it was revealed that the MS sources classified by WM-ResNet50 matched grouting records well.A solution to address insufficient diffusion under long-borehole grouting has been proposed.WM-ResNet50′s accuracy was validated through in-situ coring and XRD analysis for cement-based hydration products.This study provides a beneficial reference for similar rock signal processing and in-field grouting practices. 展开更多
关键词 Attention module Convolutional neural network Microseismic rock Grouting-induced signals Slurry diffusion
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Rock strength assessment in tectonically deformed calcareous rocks integrating equotip,ultrasound velocity,and geo-structural fracture analysis
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作者 Elisa Mammoliti Danica Jablonská +3 位作者 Antonio Ferretti Michele Morici Stefano Mazzoli Mirko Francioni 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期196-213,共18页
In complex geological environments,the analysis of drill cores to determine rock strength can be challenging due to the wide variability in the degree of fracturing,leading to subjectivity in the collection of represe... In complex geological environments,the analysis of drill cores to determine rock strength can be challenging due to the wide variability in the degree of fracturing,leading to subjectivity in the collection of representative samples for uniaxial compressive strength testing.This study evaluates non-destructive techniques on calcareous rocks with different tectonic deformations,including Equotip hardness,ultrasound P-wave velocity,thin section analysis,and calcimetry,integrated with photogrammetric fracture analysis.The investigated carbonate rock samples are sourced from drill cores derived from the Umbria-Marche fold and thrust belt(northern Apennines,Italy),including a gently dipping limb of an anticline,a hinge zone of an anticline,and a fault zone associated with a thrust.Fracture intensity,quantified by the P21 parameter using photogrammetric techniques on pre-loading rock samples,is assessed alongside macroscopic identification of discontinuities(such as stylolites,veins,and joints)using marker colours to monitor failures during uniaxial compression testing.Empirical correlations depicted by single and multi-linear relationships indicate a strong dependence between the mechanical and physical properties of limestones.Both Equotip and P-wave velocity are influenced by fracture intensity,but P-wave velocity varies significantly with discontinuity orientation,especially at 45°-90°.To refine uniaxial compressive strength predictions and mitigate multicollinearity,statistical approaches,including linear and multilinear regression,Principal Component Analysis and Gaussian Process Regression,were tested.Findings improve the reliability of non-destructive techniques for assessing rock strength in structurally complex settings,with implications for geotechnical applications. 展开更多
关键词 Non-destructive testing Uniaxial compressive strength Equotip Ultrasound pulse velocity FRACTURING Calcareous rocks
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Petrogenesis and tectonic significance of the Paleoproterozoic Chibaisong meta-mafic rocks in the northeastern Jiao-Liao-Ji Belt
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作者 ZHANG Jirui YU Hongchao +2 位作者 LIU Jin ZHANG Hongxiang ZHANG Yuanzhuhui 《Global Geology》 2026年第1期68-85,共18页
The Jiao-Liao-Ji Belt within the North China Craton had undergone a complex tectonic evolution,marked by extensive Paleoproterozoic magmatism that produced a diverse range of mafic to felsic magmatic rocks.These event... The Jiao-Liao-Ji Belt within the North China Craton had undergone a complex tectonic evolution,marked by extensive Paleoproterozoic magmatism that produced a diverse range of mafic to felsic magmatic rocks.These events provide valuable geological records for understanding the tectonic evolution of the Jiao-Liao-Ji Belt.This study focuses on the Paleoproterozoic Chibaisong meta-gabbro in southern Jilin,investigating the source of mafic magma,petrogenesis,and tectonic setting through systematic petrological analysis,zircon U-Pb dating,and geochemical studies.The findings contribute to constraining the dynamic mechanisms of Paleoproterozoic extensional rifting in the Jiao-Liao-Ji orogenic belt.Geochemical data indicate that the samples exhibit low SiO₂(47.99–50.66 wt.%),TiO₂(0.75–3.20 wt.%),Nb(3.22–8.09 ppm),and Ta(0.22–0.51 ppm)contents,along with high TFeO₃(11.97–15.82 wt.%)and MgO(5.67–12.66 wt.%)concentrations.They also show low Nb/La ratios and high(Th/Nb)N values,consistent with the geochemical characteristics of tholeiitic basalts.The samples display low total rare earth element concentrations,weak or absent Eu anomalies,slight enrichment in light rare earth elements,relatively flat heavy rare earth element patterns,and depletion in Nb,Ta,and Ti.The meta-gabbro from southern Jilin exhibits geochemical similarities to Paleoproterozoic metamafic rocks from other regions of the Jiao-Liao-Ji Belt,resembling enriched mid-ocean ridge basalts(E-MORB)with Nb,Ta,and Ti depletion.Integration of previous studies and geochemical data suggests that the 2.16–2.10 Ga metamafic rocks in the Jiao-Liao-Ji Belt experienced contamination by older crustal material.These results indicate that the 2.16–2.10 Ga metamafic rocks are unlikely to be associated with island arc,continental arc,or mid-ocean ridge settings.Instead,they are more likely related to intraplate magmatism associated with continental rifting. 展开更多
关键词 Jiao-Liao-Ji Belt North China Craton PALEOPROTEROZOIC southern Jilin region metamafic rocks
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Stress-path dependency of rock shear strength influencedby shear surface integrity:Experimental and numerical investigations
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作者 Tao Li Qiang Zhang +3 位作者 Guilei Han Hongying Wang Linpo Shi Sizhe Ye 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第2期1073-1089,共17页
Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear stre... Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear strength.To further investigate this phenomenon,this study investigates the shear behaviour of rocks with different shear surface integrities under the influenceof different stress paths through laboratory tests and numerical simulations.The results indicate that the shear strength depends on the stress path and a decrease in the shear surface integrity reduces the degree of dependence.The cohesion and friction angle of the Mohr‒Coulomb criterion decrease with weakening of the shear surface integrity.For different stress paths,the direct shear strength is always greater than that of other shear stress paths.The pattern of changes in the acoustic emission count and cumulative count indirectly reflectsthe above findings.Numerical simulations further indicate that the different principal stress states and normal suppression effects during the shearing process lead to changes in the factors of crack propagation,resulting in different mechanical behaviours under various stress paths.For rocks with different integrity levels,the main reason for the different path dependences of shear strength is that the size of the area affected by shear is different.Shear failure will concentrate on the shear plane when the normal inhibition effect is greater.This study explores the mechanism of rock shear behaviour,providing a theoretical basis for establishing more accurate constitutive models and strength criteria. 展开更多
关键词 rock integrity Stress path Shear strength Crack propagation Principal stress state
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Acoustic emission characteristics of rock salt under multistage creep-fatigue loading at various temperatures
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作者 Hang Li Chunhe Yang +5 位作者 Hongling Ma Jiangyu Fang Rui Liang Wentao Li Kai Zhao J.J.K.Daemen 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期364-379,共16页
With the growing global demand for energy,deep underground salt caverns are emerging as a potential solution for large-scale energy storage.In this study,multistage cyclic loading tests were conducted on rock salt at ... With the growing global demand for energy,deep underground salt caverns are emerging as a potential solution for large-scale energy storage.In this study,multistage cyclic loading tests were conducted on rock salt at different temperatures in combination with real-time acoustic emission(AE)monitoring.The results show that the cumulative AE count increases stepwise with increasing cyclic stress.The peak frequency is concentrated primarily in the medium-frequency range,exhibiting a band distribution across low-,medium-,and high-frequency ranges.As the temperature increases,the proportion of low-frequency signals decreases from 14.32%to 5.76%,whereas the proportion of medium-frequency signals increases from 85.48%to 94.1%.The proportion of high-frequency signals remains relatively constant between 0.1%and 0.2%.The amplitude-count relationship of the AE signals demonstrates a strong negative power-law correlation.Furthermore,with increasing temperature,the negative power-law exponent of the amplitude gradually decreases,with the b value decreasing from 1.096 to 0.837 and the a value decreasing from 7.4871 to 6.6982.Under all four temperature conditions,the dominant failure mode in rock salt is tensile cracking.However,as the temperature increases,the proportion of tensile cracks decreases from 88.59%to 75.12%,whereas the proportion of shear cracks at 80℃is nearly double that at 20℃.This finding indicates that as the temperature increases,the ductility of the material increases,and the crack propagation mode shifts from tensile to shear.This research provides valuable insights for the design and stability assessment of salt cavern reservoirs for deep underground energy storage systems. 展开更多
关键词 rock salt Cyclic loading Temperature Acoustic emission(AE) Crack type
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