目的:分析儿童IgA血管炎(immunoglobulin Avasculitis,IgAV)、IgA血管炎肾炎(immunoglobulin A vasculitis with nephritis,IgAVN)外周血红细胞分布宽度变异系数(RDW-CV)的变化特点,并探讨其对儿童IgAV肾损伤的诊断价值。方法:回顾性地...目的:分析儿童IgA血管炎(immunoglobulin Avasculitis,IgAV)、IgA血管炎肾炎(immunoglobulin A vasculitis with nephritis,IgAVN)外周血红细胞分布宽度变异系数(RDW-CV)的变化特点,并探讨其对儿童IgAV肾损伤的诊断价值。方法:回顾性地收集2017年11月-2023年12月在我院儿科住院年龄为4~14岁的IgAV患儿134例,IgAVN患儿120例;同时期健康儿童107例为对照组。利用SPSS21.0进行统计学分析血常规中NEU、LYM、RDW-CV,血Fib、D-D,尿ALB、IgG、Cr。结果:①IgAV组和IgAVN组NEU、RDW-CV均高于对照组,差异均有统计学意义(P<0.05)。②IgAVN组NEU、RDW-CV高于IgAV组,LYM低于IgAV组,差异均有统计学意义(P<0.05)。③IgAV及IgAVN患儿外周血RDW-CV水平与尿ALB/Cr、IgG/Cr呈中度正相关,未发现其与NEU、LYM、Fib、D-D之间的相关性。结论:RDW-CV在IgAV及IgAVN患儿中呈逐渐升高趋势,且IgAVN患儿高于IgAV,对患儿肾损伤的评估优于NEU、LYM,可用于监测IgAV患儿的病程进展和肾损伤的早期诊断。展开更多
介绍:本研究旨在评估红细胞体积大小的变异系数(RDW-CV)与老年人髋部骨折全因死亡率之间的关系。方法:对2015年1月至2019年9月期间在西安市红会医院接受治疗的老年髋部骨折患者进行筛选。收集患者的年龄、性别等人群特征,以及损伤机制...介绍:本研究旨在评估红细胞体积大小的变异系数(RDW-CV)与老年人髋部骨折全因死亡率之间的关系。方法:对2015年1月至2019年9月期间在西安市红会医院接受治疗的老年髋部骨折患者进行筛选。收集患者的年龄、性别等人群特征,以及损伤机制、入院基础疾病、骨折分类、从入院时间到手术、RDW-CV、手术时间、失血量、输液量、输血量、治疗策略、住院时间,随访时间等临床特征。使用多因素Cox回归模型来确定这些患者的RDW-CV和死亡率之间的关系。所有分析均使用EmpowerStats和R软件进行。结果:本回顾性队列研究共纳入2303例患者,并根据其RDW-CV水平分为三组。平均随访时间为39.23个月。RDW-CV的平均值为13.24 ± 0.48。患者一年后的全因死亡数为707例(30.69%)。多因素Cox回归模型显示,在排除了其他影响因素后,RDW-CV与老年髋部骨折患者的死亡率(风险比 = 1.13,95%置信区间:1.07~1.18,P Introduction: The purpose of our study was to evaluate the relationship between the coefficient of variation of red blood cell volume (RDW-CV) and the all-cause mortality of hip fracture in the elderly. Methods: The elderly patients with hip fracture who were treated in Xi’an Honghui Hospital from January 2015 to September 2019 were screened. The age, gender and other population characteristics of the patients were collected, as well as the injury mechanism, basic diseases at admission, fracture classification, RDW-CV, operation time, blood loss, infusion volume, blood transfusion volume, treatment strategy, hospitalization time, follow-up time and other clinical characteristics from admission time to operation. Multivariate Cox regression models were used to determine the relationship between RDW-CV and mortality in these patients. All analyses were performed using EmpowerStats and R software. Results: A total of 2303 patients were included in this retrospective cohort study and divided into three groups according to their RDW-CV levels. The average follow-up time was 39.23 months. The mean value of RDW-CV was 13.24 ± 0.48. The number of all-cause deaths after 1 year was 707 (30.69%). Multivariate Cox regression model showed that after excluding other influencing factors, RDW-CV was associated with mortality in elderly patients with hip fracture (hazard ratio = 1.13, 95% confidence interval: 1.07~1.18, P < 0.0001). When RDW-CV increased by 1%, the risk of death increased by 13%. Conclusion: The coefficient of variation of red blood cell volume size (RDW-CV) is associated with all-cause mortality in elderly patients with hip fracture, and RDW-CV can be considered as a predictor of death risk.展开更多
目的 本研究旨在分析瘢痕子宫再次妊娠时血栓弹力图(thromboelasmography,TEG)及红细胞分布宽度变异系数(red blood cell distribution width coefficient of variation,RDW-CV)、中性粒细胞/淋巴细胞比值(neutrophil to lymphocyte rat...目的 本研究旨在分析瘢痕子宫再次妊娠时血栓弹力图(thromboelasmography,TEG)及红细胞分布宽度变异系数(red blood cell distribution width coefficient of variation,RDW-CV)、中性粒细胞/淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)、单核细胞/淋巴细胞比值(monocyte lymphocyte ratio,MLR)以及全身免疫炎症指数(systemic immune-inflammation index,SII)等指标的变化情况,探讨凝血相关指标及炎症相关指标对瘢痕子宫再次妊娠风险预测价值。方法 回顾2021年3月1日至2024年3月1日在延安市人民医院产科住院的孕妇临床资料168例。比较瘢痕子宫不同妊娠阶段TEG及RDW-CV、NLR、MLR、SII等炎症指标的变化;比较瘢痕子宫孕妇与健康孕妇TEG及RDW-CV、NLR、MLR、SII等炎症指标的变化情况。结果 瘢痕子宫孕妇中,与中孕组相比,晚孕组孕妇TEG中的R值增加,Angle角、MA值减少(均P<0.05);NLR、MLR增高(P<0.05)。瘢痕子宫孕妇与健康孕妇相比,瘢痕子宫TEG中的R值、K值、Angle角、MA值的差异无统计学意义(均P>0.05);NLR、MLR差异有统计学意义(P<0.05)。结论 瘢痕子宫再次妊娠对TEG及部分炎症指标有影响,随着孕周数增加TEG指标与炎症指标有所变化;TEG及炎症指标联合检测可对瘢痕子宫再次妊娠风险作出预测。展开更多
文摘目的:分析儿童IgA血管炎(immunoglobulin Avasculitis,IgAV)、IgA血管炎肾炎(immunoglobulin A vasculitis with nephritis,IgAVN)外周血红细胞分布宽度变异系数(RDW-CV)的变化特点,并探讨其对儿童IgAV肾损伤的诊断价值。方法:回顾性地收集2017年11月-2023年12月在我院儿科住院年龄为4~14岁的IgAV患儿134例,IgAVN患儿120例;同时期健康儿童107例为对照组。利用SPSS21.0进行统计学分析血常规中NEU、LYM、RDW-CV,血Fib、D-D,尿ALB、IgG、Cr。结果:①IgAV组和IgAVN组NEU、RDW-CV均高于对照组,差异均有统计学意义(P<0.05)。②IgAVN组NEU、RDW-CV高于IgAV组,LYM低于IgAV组,差异均有统计学意义(P<0.05)。③IgAV及IgAVN患儿外周血RDW-CV水平与尿ALB/Cr、IgG/Cr呈中度正相关,未发现其与NEU、LYM、Fib、D-D之间的相关性。结论:RDW-CV在IgAV及IgAVN患儿中呈逐渐升高趋势,且IgAVN患儿高于IgAV,对患儿肾损伤的评估优于NEU、LYM,可用于监测IgAV患儿的病程进展和肾损伤的早期诊断。
文摘介绍:本研究旨在评估红细胞体积大小的变异系数(RDW-CV)与老年人髋部骨折全因死亡率之间的关系。方法:对2015年1月至2019年9月期间在西安市红会医院接受治疗的老年髋部骨折患者进行筛选。收集患者的年龄、性别等人群特征,以及损伤机制、入院基础疾病、骨折分类、从入院时间到手术、RDW-CV、手术时间、失血量、输液量、输血量、治疗策略、住院时间,随访时间等临床特征。使用多因素Cox回归模型来确定这些患者的RDW-CV和死亡率之间的关系。所有分析均使用EmpowerStats和R软件进行。结果:本回顾性队列研究共纳入2303例患者,并根据其RDW-CV水平分为三组。平均随访时间为39.23个月。RDW-CV的平均值为13.24 ± 0.48。患者一年后的全因死亡数为707例(30.69%)。多因素Cox回归模型显示,在排除了其他影响因素后,RDW-CV与老年髋部骨折患者的死亡率(风险比 = 1.13,95%置信区间:1.07~1.18,P Introduction: The purpose of our study was to evaluate the relationship between the coefficient of variation of red blood cell volume (RDW-CV) and the all-cause mortality of hip fracture in the elderly. Methods: The elderly patients with hip fracture who were treated in Xi’an Honghui Hospital from January 2015 to September 2019 were screened. The age, gender and other population characteristics of the patients were collected, as well as the injury mechanism, basic diseases at admission, fracture classification, RDW-CV, operation time, blood loss, infusion volume, blood transfusion volume, treatment strategy, hospitalization time, follow-up time and other clinical characteristics from admission time to operation. Multivariate Cox regression models were used to determine the relationship between RDW-CV and mortality in these patients. All analyses were performed using EmpowerStats and R software. Results: A total of 2303 patients were included in this retrospective cohort study and divided into three groups according to their RDW-CV levels. The average follow-up time was 39.23 months. The mean value of RDW-CV was 13.24 ± 0.48. The number of all-cause deaths after 1 year was 707 (30.69%). Multivariate Cox regression model showed that after excluding other influencing factors, RDW-CV was associated with mortality in elderly patients with hip fracture (hazard ratio = 1.13, 95% confidence interval: 1.07~1.18, P < 0.0001). When RDW-CV increased by 1%, the risk of death increased by 13%. Conclusion: The coefficient of variation of red blood cell volume size (RDW-CV) is associated with all-cause mortality in elderly patients with hip fracture, and RDW-CV can be considered as a predictor of death risk.
