BACKGROUND Atrial fibrillation,affecting approximately 33 million people globally,is the most common sustained arrhythmia,increasing risks of stroke,heart failure,and mortality.Pulmonary vein isolation via catheter ab...BACKGROUND Atrial fibrillation,affecting approximately 33 million people globally,is the most common sustained arrhythmia,increasing risks of stroke,heart failure,and mortality.Pulmonary vein isolation via catheter ablation is a key rhythm control strategy,with cryoballoon ablation(CBA)being a standard thermal method but associated with risks like phrenic nerve palsy(5%-10%),esophageal injury,and vein stenosis.Pulsed field ablation(PFA),a non-thermal technique using electrical pulses for selective electroporation,offers potential for shorter procedures and improved safety.Limited direct comparisons between PFA and CBA necessitate a systematic evaluation of their efficacy and safety.AIM To compare the procedural success,safety,and 1-year arrhythmia-free survival of PFA vs CBA for first-time pulmonary vein isolation in adults with paroxysmal or persistent atrial fibrillation.METHODS A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review and metaanalysis was conducted,searching PubMed,EMBASE,Web of Science,and other databases up to August 2025 for comparative studies.Pooled mean difference for continuous outcomes and odds ratio(OR)for dichotomous outcomes were calculated using random-effects models.Study quality was assessed with the Newcastle-Ottawa Scale,heterogeneity with I2,and publication bias with funnel plots.RESULTS Seven studies(six cohorts,one randomized controlled trial)were included,with a mean age of approximately 66 years,59%-78%male,and high prevalence of hypertension and diabetes.PFA significantly reduced procedure time(mean difference=-15.24 minutes,95%CI:-16.63 to-13.85,P<0.00001;I2=89%),improved arrhythmia-free survival(OR=1.27,95%CI:1.04-1.55,P=0.02;I2=45%),and lowered phrenic nerve palsy risk(OR=0.17,95%CI:0.04-0.63,P=0.008;I2=0%).No significant differences were found in fluoroscopy time,cardiac tamponade,repeat ablation,or vascular complications.CONCLUSION PFA demonstrates shorter procedure times,reduced phrenic nerve palsy,and better arrhythmia control compared to CBA,with comparable safety profiles.However,evidence is limited by observational study designs,heterogeneity,and potential bias.Large-scale randomized controlled trials with extended follow-up are needed to confirm these findings and guide clinical practice.展开更多
In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain ...In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain value abruptly, the charging current in the circuit is very large at the rising and falling edges. This large charging current makes measurement of the actual emissive current from the cathode difficult, constitutes a threat to the components in the circuit and causes attenuation of the emissive current within the pulse. To alleviate these drawbacks, trapezoid voltage pulses, whose rising edges are extended dramatically in comparison with square voltage pulses, are employed to extract the field emission. Under a trapezoid voltage pulse, the charging current is clearly lowered as expected. Furthermore, the heat generated by the charging current under the trapezoid voltage pulse is much smaller than that under the square voltage pulse. Hence the emissive current does not show any attenuation within the pulse. Finally, the average emissive currents are found to decrease with the repetition frequency of the pulses.展开更多
Pulsed field ablation(PFA),a promising technology for ablating arrhythmias,has significantly better efficiency and potentially greater safety than traditional ablation techniques using thermal injury.However,most clin...Pulsed field ablation(PFA),a promising technology for ablating arrhythmias,has significantly better efficiency and potentially greater safety than traditional ablation techniques using thermal injury.However,most clinical research on PFA for ablation to date has used basket-or flower-shaped catheters,thus requiring a large introducing sheath and catheter location under fluoroscopic guidance.Herein,we describe our initial experience in using a three-dimensional PFA system integrating mapping and ablation,and an annular catheter.展开更多
The increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology.Pulsed field ablation(...The increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology.Pulsed field ablation(PFA),a novel recently developed non-thermal energy-based technique,uses trains of microsecond duration high-amplitude pulses to ablate target cells.Several preclinical and clinical studies have demonstrated that PFA is a promising tool for cardiac ablation to treat arrhythmia.In addition to being an effective tissue ablation technique,PFA is safe,because it avoids damage to the surrounding cells/tissues.This review focuses on efficacy and safety outcomes reported in preclinical and clinical studies evaluating the effects of PFA on arrhythmia,and discusses limitations and potential future directions of PFA.展开更多
Split pulsed magnets are widely employed in high temperature superconducting(HTS)motor armature winding as magnetizing coils to implement in-situ pulsed field magnetization(PFM)for HTS field pole magnets.We have desig...Split pulsed magnets are widely employed in high temperature superconducting(HTS)motor armature winding as magnetizing coils to implement in-situ pulsed field magnetization(PFM)for HTS field pole magnets.We have designed and developed a compact and portable split pulsed magnet,that balances a peak central magnetic field of nearly 7 T and a rise time of 24 ms,making it particularly suitable for PFM of HTS materials at lower temperatures.Single and two-step PFM experiments of HTS GdBa_(2)Cu_(3)O_(7-δ)(GdBCO)bulk in different temperature ranges are conducted and the maximum trapped fields B_(t)are observed to be>3 T in the 40-50 K temperature range and nearly 4 T at 30 K in a 30 mm diameter GdBCO bulk.The trapped field results validate the excellent PFM ability of this designed split pulsed magnet and indicate a high trapped field(close to 4 T)can also be obtained in a coreless double armature.Moreover,multi-physical field responses of the split pulsed magnet during discharge are analyzed by a 3D field-circuit coupling model,which manifests that the split pulsed magnet is in a stable and safe operating state even under the highest charge voltage.Finally,this study may provide a novel clue for the development of coreless HTS bulk motors and suggest that HTS coreless motors can maintain a high air gap magnetic field while avoiding losses and thrust or torque fluctuations caused by iron core saturation under high magnetic fields.展开更多
In this work,we aim to develop a novel post-treatment process combining cryogenic and pulsed electric field treatment to enhance WC-Co cemented carbides.The results show a 15.62%increase in hardness from 1831.38 to 21...In this work,we aim to develop a novel post-treatment process combining cryogenic and pulsed electric field treatment to enhance WC-Co cemented carbides.The results show a 15.62%increase in hardness from 1831.38 to 2117.38 HV30,a 9.60%rise in fracture toughness from 9.06 to 9.93 MPa·m^(1/2),while the friction coefficient decreases from 0.63 to 0.47.Through the residual stress evolution,WC orientation change and the martensitic transformation of Co,and the internal enhancement mechanism of cryogenic combined with pulsed electric field treatment are revealed.The electron wind generated by the pulsed electric field can efficiently reduce the residual stress induced by cryogenic process.The evolution of residual stress promotes the base slip of WC,increasing the degree of{0001}orientation.In addition,the degree of martensitic transformation of Co intensifies,with the hcp-Co/fcc-Co ratio rising from 0.41%to 17.86%.The enhanced WC{0001}orientation and increased hcp-Co content contribute to significant improvements in hardness and wear resistance.This work provides a novel efficient enhancement strategy for ceramics and alloys,with the potential to be a mainstream strengthening method in the future.展开更多
Pulsed magnet technology is the only way to generate ultra-strong magnetic fields higher than 45 T so far.However,the inherently fast-changing field strength(typically on the order of 1000 T/s)poses significant challe...Pulsed magnet technology is the only way to generate ultra-strong magnetic fields higher than 45 T so far.However,the inherently fast-changing field strength(typically on the order of 1000 T/s)poses significant challenges for spectroscopic measurements which rely on time integration of signals to improve spectral qualities.In this work,we report high-sensitivity spectroscopic measurements under pulsed high magnetic fields employing the long flat-top pulsed magnetic field technique.By means of a multiple-capacitor power supply,we were able to generate pulsed high magnetic fields with controllable flat-top pulse width and field stabilities.By synchronizing spectroscopic measurements with the waveform of the flattop magnetic field,the integration time of each spectrum can be increased by up to 100 times compared with that of the conventional spectroscopic measurements under pulsed magnetic fields,thus enabling high-sensitivity spectroscopic measurements under ultra-strong pulsed magnetic fields.These findings promise an efficient way to significantly improve the performance and extend the application of optical measurements under pulsed high magnetic fields.展开更多
In recent years,the effect of pulsed magnetic fields on improving the solidification structure of alloys has attracted significant attention.A GH4738 nickel-based alloy smelted using a self-designed 20-kg electromagne...In recent years,the effect of pulsed magnetic fields on improving the solidification structure of alloys has attracted significant attention.A GH4738 nickel-based alloy smelted using a self-designed 20-kg electromagnetic casting system was taken as the research object.Finite element software was used to numerically simulate the magnetic field intensity,distribution,and temperature field of the casting device.The effect of the pulsed magnetic field on the solidification process of the GH4738 alloy was studied by means of low-magnification microstructural analysis.The measured magnetic field shows that when the duty cycle is 20%,the pulse frequency is 50 Hz,the output current is in the range of 150–250 A,and the peak magnetic field intensity of the crucible center is 68–116 mT.The crucible temperature is heated to 600℃and the melt center solidification time is 12.844 s.The microstructural analysis of the ingot shows that its shrinkage hole is reduced from 130 to 100 mm,and the equiaxed crystal area is increased from 2275 to 3150 mm^(2).The solidification angle of the dendrite is changed under the action of the pulsed magnetic field,and the tilt angle is 45°.The results show that the pulsed magnetic field promotes the primary crystal core of the GH4738 alloy,improves the nucleation rate of the melt,reduces the size difference of the solidification structure between the center and the edge of the ingot,and improves the uniformity of the solidification structure.展开更多
The corrosion resistance of cobalt-based alloy cladding layers is crucial for the long-term reliability of materials in the nuclear power industry,where they are exposed to highly aggressive environmental conditions.A...The corrosion resistance of cobalt-based alloy cladding layers is crucial for the long-term reliability of materials in the nuclear power industry,where they are exposed to highly aggressive environmental conditions.A major challenge to their performance is the corrosion occurring at phase boundaries under harsh operating conditions.This study investigates the effects of pulsed magnetic field treatment(PMT)on improving corrosion resistance at phase boundaries,specifically at the carbide/matrix Co interface,and seeks to clarify the underlying mechanisms.Advanced characterization techniques,including scanning electron microscopy(SEM),in situ transmission electron microscopy(TEM),in situ scanning kelvin probe force microscopy(SKPFM),and density functional theory(DFT)calculations,were employed.PMT samples exhibited no interface corrosion cracking or carbide spalling and showed a significant reduction in corrosion depth.TEM analysis revealed reduced lattice distortion at phase boundaries and a partial transformation of face-centered cubic(FCC)Co to hexagonal closepacked(HCP)Co.The enhanced corrosion resistance at phase boundaries is attributed to changes in the electronic work function(EWF),as determined by SKPFM measurements and DFT calculations.展开更多
During direct chilling(DC)casting of ZK61 alloys,the primary and secondary cooling causes strong thermal gradients,which leads to the uneven crystallization rate and thermal contraction in different positions of the i...During direct chilling(DC)casting of ZK61 alloys,the primary and secondary cooling causes strong thermal gradients,which leads to the uneven crystallization rate and thermal contraction in different positions of the ingot.The consequences manifested appearance of heterogeneous grains,huge casting stresses,and even hot cracking flaws.In this paper,chemical and physical methods were integrated to produce large-scale magnesium(Mg)alloy ingots.A φ525 mm ZK61-RE alloy ingot that was refined,homogeneous,and free from hot cracking was obtained via the DC process coupled with a differential low frequency pulsed magnetic field(DLPM).The effects of rare earth(RE)and DLPM on the hot cracking tendency were investigated,and the mechanism of hot cracking formation and modification in largescale ingots was revealed.The findings indicate that the addition of moderate amounts of RE lessens the tendency of hot cracking in large-scale ZK61 alloy ingots.This is mainly attributed to the addition of RE increases the content of the second phase,thus enhancing the ability of the eutectic liquid phase to feed the cracking.With the introduction of DLPM,the grain sizes are significantly refined and homogenized,and there is no obvious hot cracking observed in the ingot.This is because the coupling of the DLPM provides a more homogeneous temperature field,leading to the synchronization of the solidification process,and the consequent reduction of the casting stress,thus reducing the driving force for the formation of hot cracking.In addition,the casting conditions are modified to enhance the ability of solidification feeding and the resistance to hot cracking.This work provides theoretical and practical references for the preparation of large-scale high-quality Mg alloy ingots.展开更多
The effects of a low-voltage pulsed magnetic field on the solidified structure and mechanical properties of DC casting AZ80 magnesium alloy were investigated.The results showed that the solidified structure of the DC ...The effects of a low-voltage pulsed magnetic field on the solidified structure and mechanical properties of DC casting AZ80 magnesium alloy were investigated.The results showed that the solidified structure of the DC casting AZ80 magnesium alloy was refined obviously by the low-voltage pulsed magnetic field and significant grain refinement in the DC casting ingot of AZ80 magnesium alloy was achieved.Meanwhile,the morphology of the dentritic in the DC casting ingot was transformed from coarse dentritic to fine rosette with the application of low-voltage pulsed magnetic field.The ability of deformation of the ingot was enhanced and especially the plasticity of the ingot center after upsetting was improved greatly by more than 80%after deformation.展开更多
The grain refinement of superalloy IN718 under the action of low voltage pulsed magnetic field was investigated. The experimental results show that fine equiaxed grains are acquired under the action of low voltage pul...The grain refinement of superalloy IN718 under the action of low voltage pulsed magnetic field was investigated. The experimental results show that fine equiaxed grains are acquired under the action of low voltage pulsed magnetic field. The refinement effect of the pulsed magnetic field is affected by the melt cooling rate and superheating. The decrease of cooling rate and superheating enhance the refinement effect of the low voltage pulsed magnetic field. The magnetic force and the melt flow during solidification are modeled and simulated to reveal the grain refinement mechanism. It is considered that the melt convection caused by the pulsed magnetic field, as well as cooling rate and superheating contributes to the refinement of solidified grains.展开更多
The combined effects of direct current pulsed magnetic field （DC-PMF） and inoculation on pure aluminum were investigated, the grain refinement behavior of DC-PMF and inoculation was discussed. The experimental resul...The combined effects of direct current pulsed magnetic field （DC-PMF） and inoculation on pure aluminum were investigated, the grain refinement behavior of DC-PMF and inoculation was discussed. The experimental results indicate that the solidification micro structure of pure aluminum can be greatly refined under DC-PMF. Refinement of pure aluminum is attributed to electromagnetic undercooling and forced convection caused by DC-PMF. With single DC-PMF, the grain size in the equiaxed zone is uneven. However, under DC-PMF, by adding 0.05% （mass fraction） Al5Ti-B, the grain size of the sample is smaller, and the size distribution is more uniform than that of single DC-PMF. Furthermore, under the combination of DC-PMF and inoculation, with the increase of output current, the grain size is further reduced. When the output current increases to 100 A, the average grain size can decrease to 113 μn.展开更多
Pulsed field gel electrophoresis(PFGE) has been firstly introduced in characterization of the pathogenic fungi Penicillium marne f fei and Exophiala dermatitidis genomes.The numbers and sizes of their chromosomes have...Pulsed field gel electrophoresis(PFGE) has been firstly introduced in characterization of the pathogenic fungi Penicillium marne f fei and Exophiala dermatitidis genomes.The numbers and sizes of their chromosomes have been detected.Polymorphism was identified on the smallest chromosome of E.dermatitidis.The result shows that PFGE for characterization of large molecular DNA pathogenic fungi is very suitable,it is more simple and more efficacy.The result also shows the diversity of pathogenic fungi is relative common even in rare occurred pathogenic fungi such as E.dermatitidis.展开更多
Clinical outcomes of catheter ablation remain suboptimal in patients with atrial fibrillation(AF),particularly in those with persistent AF,despite decades of research,clinical trials,and technological advancements.Rec...Clinical outcomes of catheter ablation remain suboptimal in patients with atrial fibrillation(AF),particularly in those with persistent AF,despite decades of research,clinical trials,and technological advancements.Recently,pulsed-field ablation(PFA),a promising non-thermal technology,has been introduced to improve procedural outcomes.Its unique feature of myocardial selectivity offers safety advantages by avoiding potential harm to vulnerable adjacent structures during AF ablation.However,despite the global enthusiasm within the electro-physiology community,recent data indicate that PFA is still far from being a“magic wand”for addressing such a complex and challenging arrhythmia as AF.More progress is needed in mapping processes rather than in ablation technology.This editorial reviews relevant available data and explores future research directions for PFA.展开更多
An array of three GdBa_(2)Cu_(3)O_(7‐δ)bulk high‐temperature superconductors(HTS)that mimic the field pole of a high‐power superconducting motor had been magnetized by pulsed field magnetization(PFM)while cooled b...An array of three GdBa_(2)Cu_(3)O_(7‐δ)bulk high‐temperature superconductors(HTS)that mimic the field pole of a high‐power superconducting motor had been magnetized by pulsed field magnetization(PFM)while cooled by liquid nitrogen.The bulk array was magnetized by a passive PFM technique using three vortex‐type coils placed over each individual bulk and connected in series.The trapped magnetic flux density distribution was comparable to the distribution obtained with more traditional quasi‐static magnetization such as field‐cooling.This suggests that the use of PFM technique on arrays of HTS bulks is possible.PFM has also been performed using each coil individually,to magnetize each bulk sequentially.The magnetization sequences showed a maximum reduction of the peak trapped magnetic flux density of 12%due to the demagnetization effect of the magnetization sequence,while the trapped magnetization distribution was improved.展开更多
The structures and macro-segregation of 2124 Al-alloy were studied when a pulsed magnetic field (PMF) was applied during solidification. It is found through experi-ments that a remarkable change occurs in the solidifi...The structures and macro-segregation of 2124 Al-alloy were studied when a pulsed magnetic field (PMF) was applied during solidification. It is found through experi-ments that a remarkable change occurs in the solidification structures of 2124 Al-alloy under pulsed magnetic field. The eutectic phase at grain boundaries change from thick continuous eutectic network to thin discontinuous one, and the distribution of solute elements was also homogenized. The typical negative segregation phenomenon of Cu in common solidification condition was restrained, and the segregation of Mg decreased.展开更多
The effects of a pulsed magnetic field （PMF） on the microsegregation of solute elements during directional solidification of a Ni-based single crystal superalloy were experimentally investigated, and the results sho...The effects of a pulsed magnetic field （PMF） on the microsegregation of solute elements during directional solidification of a Ni-based single crystal superalloy were experimentally investigated, and the results show that the PMF significantly affects the microsegregation of Al, Ti, Co, Mo and W elements in the alloy. However, the distribution behavior differs for both positive and negative segregation elements. With the PMF, the microsegregation of negative segregation elements, Co and W, was restrained effectively, while that of positive segregation elements, A1, Ti and Mo, was aggravated. A segregation model was estab- lished to reveal the distribution mechanism of the elements with PME It is considered that, under the action of PME the jumping of solute atoms from the liquid phase to solid phase is hindered, but the jumping of solute atoms from the solid phase into liquid phase is promoted during solidification. As a result, the effective distribution coefficient of the solute atoms is reduced, which leads to the reduction of microsegregation of negative segregation elements and aggravation of microsegregation of positive segregation elements.展开更多
The effects of a pulsed magnetic field on the solidified microstructure of an AZ31 magnesium alloy were investigated.The experimental results show that the remarkable microstructural refinement is achieved when the pu...The effects of a pulsed magnetic field on the solidified microstructure of an AZ31 magnesium alloy were investigated.The experimental results show that the remarkable microstructural refinement is achieved when the pulsed magnetic field is applied to the solidification of the AZ31 alloy.The average grain size of the as-cast microstructure of the AZ31 alloy is refined to 107 μm.By quenching the AZ31 alloy, the different primary α-Mg microstructures are preserved during the course of solidification.The microstructure evolution reveals that the primary α-Mg generates and grows in globular shape with pulsed magnetic field, contrast with the dendritic shape without pulsed magnetic field.The pulsed magnetic field causes melt convection during solidification, which makes the temperature of the whole melt homogenized, and produces an undercooling zone in front of the liquid/solid interface, which makes the nucleation rate increased and big dendrites prohibited.In addition, the Joule heat effect induced in the melt also strengthens the grain refinement effect and spheroidization of dendrite arms.展开更多
The low voltage pulsed magnetic field(LVPMF)disrupts the columnar dendrite growth,and the columnarto-equiaxed transition(CET)occurs during the directional solidification of superalloy K4169.Within the pulse voltage ra...The low voltage pulsed magnetic field(LVPMF)disrupts the columnar dendrite growth,and the columnarto-equiaxed transition(CET)occurs during the directional solidification of superalloy K4169.Within the pulse voltage ranging from 100Vto 200 V,a transition from columnar to equiaxed grain was observed,and the grain size decreased as the pulse voltage rised.As the pulse frequency increased,the CET occurred,and the grains were refined.However,the grains became coarse,and the solidification structure was columnar crystal again when frequency increased to 10 Hz.The LVPMF had an optimal frequency to promote CET.The LVPMF on the CET was affected by the withdrawal speed and increasing the withdrawal speed enhances the CET.The distribution of electromagnetic force and flow field in the melt under the LVPMF were modeled and simulated to reveal the CET mechanism.It is considered that the CET should be attributed to the coupling effects of magnetic vibration and melt convection induced by the LVPMF.展开更多
文摘BACKGROUND Atrial fibrillation,affecting approximately 33 million people globally,is the most common sustained arrhythmia,increasing risks of stroke,heart failure,and mortality.Pulmonary vein isolation via catheter ablation is a key rhythm control strategy,with cryoballoon ablation(CBA)being a standard thermal method but associated with risks like phrenic nerve palsy(5%-10%),esophageal injury,and vein stenosis.Pulsed field ablation(PFA),a non-thermal technique using electrical pulses for selective electroporation,offers potential for shorter procedures and improved safety.Limited direct comparisons between PFA and CBA necessitate a systematic evaluation of their efficacy and safety.AIM To compare the procedural success,safety,and 1-year arrhythmia-free survival of PFA vs CBA for first-time pulmonary vein isolation in adults with paroxysmal or persistent atrial fibrillation.METHODS A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review and metaanalysis was conducted,searching PubMed,EMBASE,Web of Science,and other databases up to August 2025 for comparative studies.Pooled mean difference for continuous outcomes and odds ratio(OR)for dichotomous outcomes were calculated using random-effects models.Study quality was assessed with the Newcastle-Ottawa Scale,heterogeneity with I2,and publication bias with funnel plots.RESULTS Seven studies(six cohorts,one randomized controlled trial)were included,with a mean age of approximately 66 years,59%-78%male,and high prevalence of hypertension and diabetes.PFA significantly reduced procedure time(mean difference=-15.24 minutes,95%CI:-16.63 to-13.85,P<0.00001;I2=89%),improved arrhythmia-free survival(OR=1.27,95%CI:1.04-1.55,P=0.02;I2=45%),and lowered phrenic nerve palsy risk(OR=0.17,95%CI:0.04-0.63,P=0.008;I2=0%).No significant differences were found in fluoroscopy time,cardiac tamponade,repeat ablation,or vascular complications.CONCLUSION PFA demonstrates shorter procedure times,reduced phrenic nerve palsy,and better arrhythmia control compared to CBA,with comparable safety profiles.However,evidence is limited by observational study designs,heterogeneity,and potential bias.Large-scale randomized controlled trials with extended follow-up are needed to confirm these findings and guide clinical practice.
基金Supported by the Natural Science Foundation of Jiangsu Province of China under Grant Nos BK20161243 and BK20161242the National Natural Science Foundation of China under Grant No 61774007
文摘In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain value abruptly, the charging current in the circuit is very large at the rising and falling edges. This large charging current makes measurement of the actual emissive current from the cathode difficult, constitutes a threat to the components in the circuit and causes attenuation of the emissive current within the pulse. To alleviate these drawbacks, trapezoid voltage pulses, whose rising edges are extended dramatically in comparison with square voltage pulses, are employed to extract the field emission. Under a trapezoid voltage pulse, the charging current is clearly lowered as expected. Furthermore, the heat generated by the charging current under the trapezoid voltage pulse is much smaller than that under the square voltage pulse. Hence the emissive current does not show any attenuation within the pulse. Finally, the average emissive currents are found to decrease with the repetition frequency of the pulses.
文摘Pulsed field ablation(PFA),a promising technology for ablating arrhythmias,has significantly better efficiency and potentially greater safety than traditional ablation techniques using thermal injury.However,most clinical research on PFA for ablation to date has used basket-or flower-shaped catheters,thus requiring a large introducing sheath and catheter location under fluoroscopic guidance.Herein,we describe our initial experience in using a three-dimensional PFA system integrating mapping and ablation,and an annular catheter.
基金This work was supported by grants from National Natural Science Foundation of China(No.81871486,82270532,81970287,82100530,and 82200556)the Foundation for Innovative Research Groups of Natural Science Foundation of Hubei Province,China(2021CFA010).
文摘The increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology.Pulsed field ablation(PFA),a novel recently developed non-thermal energy-based technique,uses trains of microsecond duration high-amplitude pulses to ablate target cells.Several preclinical and clinical studies have demonstrated that PFA is a promising tool for cardiac ablation to treat arrhythmia.In addition to being an effective tissue ablation technique,PFA is safe,because it avoids damage to the surrounding cells/tissues.This review focuses on efficacy and safety outcomes reported in preclinical and clinical studies evaluating the effects of PFA on arrhythmia,and discusses limitations and potential future directions of PFA.
基金supported by the National Natural Science Foundation of China(52377021).
文摘Split pulsed magnets are widely employed in high temperature superconducting(HTS)motor armature winding as magnetizing coils to implement in-situ pulsed field magnetization(PFM)for HTS field pole magnets.We have designed and developed a compact and portable split pulsed magnet,that balances a peak central magnetic field of nearly 7 T and a rise time of 24 ms,making it particularly suitable for PFM of HTS materials at lower temperatures.Single and two-step PFM experiments of HTS GdBa_(2)Cu_(3)O_(7-δ)(GdBCO)bulk in different temperature ranges are conducted and the maximum trapped fields B_(t)are observed to be>3 T in the 40-50 K temperature range and nearly 4 T at 30 K in a 30 mm diameter GdBCO bulk.The trapped field results validate the excellent PFM ability of this designed split pulsed magnet and indicate a high trapped field(close to 4 T)can also be obtained in a coreless double armature.Moreover,multi-physical field responses of the split pulsed magnet during discharge are analyzed by a 3D field-circuit coupling model,which manifests that the split pulsed magnet is in a stable and safe operating state even under the highest charge voltage.Finally,this study may provide a novel clue for the development of coreless HTS bulk motors and suggest that HTS coreless motors can maintain a high air gap magnetic field while avoiding losses and thrust or torque fluctuations caused by iron core saturation under high magnetic fields.
基金supported by the National Natural Science Foundation of China(Nos.U21A20399 and 52274407)Liaoning Province Applied Basic Research Program(No.2022JH2/101300212).
文摘In this work,we aim to develop a novel post-treatment process combining cryogenic and pulsed electric field treatment to enhance WC-Co cemented carbides.The results show a 15.62%increase in hardness from 1831.38 to 2117.38 HV30,a 9.60%rise in fracture toughness from 9.06 to 9.93 MPa·m^(1/2),while the friction coefficient decreases from 0.63 to 0.47.Through the residual stress evolution,WC orientation change and the martensitic transformation of Co,and the internal enhancement mechanism of cryogenic combined with pulsed electric field treatment are revealed.The electron wind generated by the pulsed electric field can efficiently reduce the residual stress induced by cryogenic process.The evolution of residual stress promotes the base slip of WC,increasing the degree of{0001}orientation.In addition,the degree of martensitic transformation of Co intensifies,with the hcp-Co/fcc-Co ratio rising from 0.41%to 17.86%.The enhanced WC{0001}orientation and increased hcp-Co content contribute to significant improvements in hardness and wear resistance.This work provides a novel efficient enhancement strategy for ceramics and alloys,with the potential to be a mainstream strengthening method in the future.
基金financially supported by the National Key Research and Development Program of China(Grant No.2022YFA1602700)the National Natural Science Foundation of China(Grant No.12274159)。
文摘Pulsed magnet technology is the only way to generate ultra-strong magnetic fields higher than 45 T so far.However,the inherently fast-changing field strength(typically on the order of 1000 T/s)poses significant challenges for spectroscopic measurements which rely on time integration of signals to improve spectral qualities.In this work,we report high-sensitivity spectroscopic measurements under pulsed high magnetic fields employing the long flat-top pulsed magnetic field technique.By means of a multiple-capacitor power supply,we were able to generate pulsed high magnetic fields with controllable flat-top pulse width and field stabilities.By synchronizing spectroscopic measurements with the waveform of the flattop magnetic field,the integration time of each spectrum can be increased by up to 100 times compared with that of the conventional spectroscopic measurements under pulsed magnetic fields,thus enabling high-sensitivity spectroscopic measurements under ultra-strong pulsed magnetic fields.These findings promise an efficient way to significantly improve the performance and extend the application of optical measurements under pulsed high magnetic fields.
基金supported by National Natural Science Foundation of China(No.52074092)the Fundamental Research Funds for Inner Mongolia University of Science&Technology(No.2023QNJS007)+1 种基金Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(No.NJYT23115)the Inner Mongolia Natural Science Foundation(No.2022MS05039).
文摘In recent years,the effect of pulsed magnetic fields on improving the solidification structure of alloys has attracted significant attention.A GH4738 nickel-based alloy smelted using a self-designed 20-kg electromagnetic casting system was taken as the research object.Finite element software was used to numerically simulate the magnetic field intensity,distribution,and temperature field of the casting device.The effect of the pulsed magnetic field on the solidification process of the GH4738 alloy was studied by means of low-magnification microstructural analysis.The measured magnetic field shows that when the duty cycle is 20%,the pulse frequency is 50 Hz,the output current is in the range of 150–250 A,and the peak magnetic field intensity of the crucible center is 68–116 mT.The crucible temperature is heated to 600℃and the melt center solidification time is 12.844 s.The microstructural analysis of the ingot shows that its shrinkage hole is reduced from 130 to 100 mm,and the equiaxed crystal area is increased from 2275 to 3150 mm^(2).The solidification angle of the dendrite is changed under the action of the pulsed magnetic field,and the tilt angle is 45°.The results show that the pulsed magnetic field promotes the primary crystal core of the GH4738 alloy,improves the nucleation rate of the melt,reduces the size difference of the solidification structure between the center and the edge of the ingot,and improves the uniformity of the solidification structure.
基金financially supported by the National Key Research and Development Program of China(No.2020YFA0714900)the Joint Fund of the Ministry of Education(No.8091B012201)
文摘The corrosion resistance of cobalt-based alloy cladding layers is crucial for the long-term reliability of materials in the nuclear power industry,where they are exposed to highly aggressive environmental conditions.A major challenge to their performance is the corrosion occurring at phase boundaries under harsh operating conditions.This study investigates the effects of pulsed magnetic field treatment(PMT)on improving corrosion resistance at phase boundaries,specifically at the carbide/matrix Co interface,and seeks to clarify the underlying mechanisms.Advanced characterization techniques,including scanning electron microscopy(SEM),in situ transmission electron microscopy(TEM),in situ scanning kelvin probe force microscopy(SKPFM),and density functional theory(DFT)calculations,were employed.PMT samples exhibited no interface corrosion cracking or carbide spalling and showed a significant reduction in corrosion depth.TEM analysis revealed reduced lattice distortion at phase boundaries and a partial transformation of face-centered cubic(FCC)Co to hexagonal closepacked(HCP)Co.The enhanced corrosion resistance at phase boundaries is attributed to changes in the electronic work function(EWF),as determined by SKPFM measurements and DFT calculations.
基金Project supported by the Jiangxi Province Key Laboratory of Light Alloy(2024SSY05031)the National Natural Science Foundation of China(52061028)+1 种基金the National Key Research and Development Program of China(2021YFB3501001)the Major Research and Development Projects of Jiangxi Province(20223BBE51021,20213AAE02014)。
文摘During direct chilling(DC)casting of ZK61 alloys,the primary and secondary cooling causes strong thermal gradients,which leads to the uneven crystallization rate and thermal contraction in different positions of the ingot.The consequences manifested appearance of heterogeneous grains,huge casting stresses,and even hot cracking flaws.In this paper,chemical and physical methods were integrated to produce large-scale magnesium(Mg)alloy ingots.A φ525 mm ZK61-RE alloy ingot that was refined,homogeneous,and free from hot cracking was obtained via the DC process coupled with a differential low frequency pulsed magnetic field(DLPM).The effects of rare earth(RE)and DLPM on the hot cracking tendency were investigated,and the mechanism of hot cracking formation and modification in largescale ingots was revealed.The findings indicate that the addition of moderate amounts of RE lessens the tendency of hot cracking in large-scale ZK61 alloy ingots.This is mainly attributed to the addition of RE increases the content of the second phase,thus enhancing the ability of the eutectic liquid phase to feed the cracking.With the introduction of DLPM,the grain sizes are significantly refined and homogenized,and there is no obvious hot cracking observed in the ingot.This is because the coupling of the DLPM provides a more homogeneous temperature field,leading to the synchronization of the solidification process,and the consequent reduction of the casting stress,thus reducing the driving force for the formation of hot cracking.In addition,the casting conditions are modified to enhance the ability of solidification feeding and the resistance to hot cracking.This work provides theoretical and practical references for the preparation of large-scale high-quality Mg alloy ingots.
基金Project(51034012)supported by the the National Natural Science Foundation of ChinaProject(2013CB632205)supported by the National Basic Research Program of China
文摘The effects of a low-voltage pulsed magnetic field on the solidified structure and mechanical properties of DC casting AZ80 magnesium alloy were investigated.The results showed that the solidified structure of the DC casting AZ80 magnesium alloy was refined obviously by the low-voltage pulsed magnetic field and significant grain refinement in the DC casting ingot of AZ80 magnesium alloy was achieved.Meanwhile,the morphology of the dentritic in the DC casting ingot was transformed from coarse dentritic to fine rosette with the application of low-voltage pulsed magnetic field.The ability of deformation of the ingot was enhanced and especially the plasticity of the ingot center after upsetting was improved greatly by more than 80%after deformation.
基金Project(2010CB631205)supported by the National Basic Research Program of ChinaProject(51034012)supported by the National Natural Science Foundation of China
文摘The grain refinement of superalloy IN718 under the action of low voltage pulsed magnetic field was investigated. The experimental results show that fine equiaxed grains are acquired under the action of low voltage pulsed magnetic field. The refinement effect of the pulsed magnetic field is affected by the melt cooling rate and superheating. The decrease of cooling rate and superheating enhance the refinement effect of the low voltage pulsed magnetic field. The magnetic force and the melt flow during solidification are modeled and simulated to reveal the grain refinement mechanism. It is considered that the melt convection caused by the pulsed magnetic field, as well as cooling rate and superheating contributes to the refinement of solidified grains.
基金Projects(51074031,51271042,50874022)supported by the National Natural Science Foundation of ChinaProject(2013M530913)supported by the China Postdoctoral Science FoundationProject(DUT12RC(3)35)supported by the Fundamental Research Funds for the Central Universities of China
文摘The combined effects of direct current pulsed magnetic field （DC-PMF） and inoculation on pure aluminum were investigated, the grain refinement behavior of DC-PMF and inoculation was discussed. The experimental results indicate that the solidification micro structure of pure aluminum can be greatly refined under DC-PMF. Refinement of pure aluminum is attributed to electromagnetic undercooling and forced convection caused by DC-PMF. With single DC-PMF, the grain size in the equiaxed zone is uneven. However, under DC-PMF, by adding 0.05% （mass fraction） Al5Ti-B, the grain size of the sample is smaller, and the size distribution is more uniform than that of single DC-PMF. Furthermore, under the combination of DC-PMF and inoculation, with the increase of output current, the grain size is further reduced. When the output current increases to 100 A, the average grain size can decrease to 113 μn.
文摘Pulsed field gel electrophoresis(PFGE) has been firstly introduced in characterization of the pathogenic fungi Penicillium marne f fei and Exophiala dermatitidis genomes.The numbers and sizes of their chromosomes have been detected.Polymorphism was identified on the smallest chromosome of E.dermatitidis.The result shows that PFGE for characterization of large molecular DNA pathogenic fungi is very suitable,it is more simple and more efficacy.The result also shows the diversity of pathogenic fungi is relative common even in rare occurred pathogenic fungi such as E.dermatitidis.
文摘Clinical outcomes of catheter ablation remain suboptimal in patients with atrial fibrillation(AF),particularly in those with persistent AF,despite decades of research,clinical trials,and technological advancements.Recently,pulsed-field ablation(PFA),a promising non-thermal technology,has been introduced to improve procedural outcomes.Its unique feature of myocardial selectivity offers safety advantages by avoiding potential harm to vulnerable adjacent structures during AF ablation.However,despite the global enthusiasm within the electro-physiology community,recent data indicate that PFA is still far from being a“magic wand”for addressing such a complex and challenging arrhythmia as AF.More progress is needed in mapping processes rather than in ablation technology.This editorial reviews relevant available data and explores future research directions for PFA.
基金supported by JSPS KAKENHI Grant Numbers 20K21044(2020–2022).
文摘An array of three GdBa_(2)Cu_(3)O_(7‐δ)bulk high‐temperature superconductors(HTS)that mimic the field pole of a high‐power superconducting motor had been magnetized by pulsed field magnetization(PFM)while cooled by liquid nitrogen.The bulk array was magnetized by a passive PFM technique using three vortex‐type coils placed over each individual bulk and connected in series.The trapped magnetic flux density distribution was comparable to the distribution obtained with more traditional quasi‐static magnetization such as field‐cooling.This suggests that the use of PFM technique on arrays of HTS bulks is possible.PFM has also been performed using each coil individually,to magnetize each bulk sequentially.The magnetization sequences showed a maximum reduction of the peak trapped magnetic flux density of 12%due to the demagnetization effect of the magnetization sequence,while the trapped magnetization distribution was improved.
基金This research was supported by National Key Basic Research and Development Programme of China "973" (No. G19990649051).
文摘The structures and macro-segregation of 2124 Al-alloy were studied when a pulsed magnetic field (PMF) was applied during solidification. It is found through experi-ments that a remarkable change occurs in the solidification structures of 2124 Al-alloy under pulsed magnetic field. The eutectic phase at grain boundaries change from thick continuous eutectic network to thin discontinuous one, and the distribution of solute elements was also homogenized. The typical negative segregation phenomenon of Cu in common solidification condition was restrained, and the segregation of Mg decreased.
基金the financial support from the National Natural Science Foundation of China(No.51034012)the National Basic Research Program of China(No.2010CB631205)
文摘The effects of a pulsed magnetic field （PMF） on the microsegregation of solute elements during directional solidification of a Ni-based single crystal superalloy were experimentally investigated, and the results show that the PMF significantly affects the microsegregation of Al, Ti, Co, Mo and W elements in the alloy. However, the distribution behavior differs for both positive and negative segregation elements. With the PMF, the microsegregation of negative segregation elements, Co and W, was restrained effectively, while that of positive segregation elements, A1, Ti and Mo, was aggravated. A segregation model was estab- lished to reveal the distribution mechanism of the elements with PME It is considered that, under the action of PME the jumping of solute atoms from the liquid phase to solid phase is hindered, but the jumping of solute atoms from the solid phase into liquid phase is promoted during solidification. As a result, the effective distribution coefficient of the solute atoms is reduced, which leads to the reduction of microsegregation of negative segregation elements and aggravation of microsegregation of positive segregation elements.
基金Project(ZC304009103) supported by the Doctoral Fund of Zhejiang Normal University,ChinaProject(KYJ06Y09157) supported by School-level Project of Zhejiang Normal University,China
文摘The effects of a pulsed magnetic field on the solidified microstructure of an AZ31 magnesium alloy were investigated.The experimental results show that the remarkable microstructural refinement is achieved when the pulsed magnetic field is applied to the solidification of the AZ31 alloy.The average grain size of the as-cast microstructure of the AZ31 alloy is refined to 107 μm.By quenching the AZ31 alloy, the different primary α-Mg microstructures are preserved during the course of solidification.The microstructure evolution reveals that the primary α-Mg generates and grows in globular shape with pulsed magnetic field, contrast with the dendritic shape without pulsed magnetic field.The pulsed magnetic field causes melt convection during solidification, which makes the temperature of the whole melt homogenized, and produces an undercooling zone in front of the liquid/solid interface, which makes the nucleation rate increased and big dendrites prohibited.In addition, the Joule heat effect induced in the melt also strengthens the grain refinement effect and spheroidization of dendrite arms.
基金supported by the National Natural Science Foundation of China(No.51674236)the Key Research and Development Program of Liaoning Province(2019JH2/10100009)+1 种基金the National Science and Technology Major Project(No.2017-VI-00-0073)the National Key Research and Development Program(No.2018YFA0702900).
文摘The low voltage pulsed magnetic field(LVPMF)disrupts the columnar dendrite growth,and the columnarto-equiaxed transition(CET)occurs during the directional solidification of superalloy K4169.Within the pulse voltage ranging from 100Vto 200 V,a transition from columnar to equiaxed grain was observed,and the grain size decreased as the pulse voltage rised.As the pulse frequency increased,the CET occurred,and the grains were refined.However,the grains became coarse,and the solidification structure was columnar crystal again when frequency increased to 10 Hz.The LVPMF had an optimal frequency to promote CET.The LVPMF on the CET was affected by the withdrawal speed and increasing the withdrawal speed enhances the CET.The distribution of electromagnetic force and flow field in the melt under the LVPMF were modeled and simulated to reveal the CET mechanism.It is considered that the CET should be attributed to the coupling effects of magnetic vibration and melt convection induced by the LVPMF.
