Mobile crowdsensing(MCS)has become an effective paradigm to facilitate urban sensing.However,mobile users participating in sensing tasks will face the risk of location privacy leakage when uploading their actual sensi...Mobile crowdsensing(MCS)has become an effective paradigm to facilitate urban sensing.However,mobile users participating in sensing tasks will face the risk of location privacy leakage when uploading their actual sensing location data.In the application of mobile crowdsensing,most location privacy protection studies do not consider the temporal correlations between locations,so they are vulnerable to various inference attacks,and there is the problem of low data availability.In order to solve the above problems,this paper proposes a dynamic differential location privacy data publishing framework(DDLP)that protects privacy while publishing locations continuously.Firstly,the corresponding Markov transition matrices are established according to different times of historical trajectories,and then the protection location set is generated based on the current location at each timestamp.Moreover,using the exponential mechanism in differential privacy perturbs the true location by designing the utility function.Finally,experiments on the real-world trajectory dataset show that our method not only provides strong privacy guarantees,but also outperforms existing methods in terms of data availability and computational efficiency.展开更多
针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供...针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供电波动抑制及转速信号稳定输出3个方面分析LPS冗余供电在稳定性改造方面的应用,并结合工程实例对改造效果进行对比分析。结果表明,引入LPS冗余供电能够有效提升偏航转速传感器运行稳定性,具有良好的工程应用价值。展开更多
Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in rece...Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in recent research as a crucial mediator of the inflammatory pathways underlying sepsis.In this study,we used a murine model of lipopolysaccharide(LPS)-induced endotoxemia to assess the therapeutic potential of 6H2,a monoclonal antibody that targets A-FABP.In comparison to untreated septic mice,6H2 treatment significantly increased survival rates,decreased histopathological damage in the liver,lungs,kidneys,and heart,and reduced systemic inflammation.According to biochemical analyses,6H2 treatment decreased circulating levels of A-FABP,and this was associated with a reduction in inflammatory markers.These results indicate that A-FABP inhibition is a potentially effective treatment approach for sepsis,with 6H2 demonstrating strong therapeutic efficacy.展开更多
Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions....Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions.To address this issue,this paper employs a combined approach of theoretical analysis and case study,introducing the SICAS(Sense-Interest-Connection-Action-Share)user consumption behavior analysis model and selecting“CITIC Academy”as the case study subject.It systematically examines and summarizes the platform’s operational practices and specific strategies,aiming to offer strategic insights and practical references for the operational improvement and sustainable,high-quality development of trade publishing knowledge service platforms.展开更多
基金supported by the Inner Mongolia Natural Science Foundation(Grant No.2023MS06022)the University Youth Science and Technology Talent Development Project(Innovation Group Development Plan)of Inner Mongolia A.R.of China(Grant No.NMGIRT2318)+1 种基金the“Inner Mongolia Science and Technology Achievement Transfer and Transformation Demonstration Zone,University Collaborative Innovation Base,and University Entrepreneurship Training Base”Construction Project(Supercomputing Power Project)(Grant No.21300-231510)the Engineering Research Center of Ecological Big Data,Ministry of Education.
文摘Mobile crowdsensing(MCS)has become an effective paradigm to facilitate urban sensing.However,mobile users participating in sensing tasks will face the risk of location privacy leakage when uploading their actual sensing location data.In the application of mobile crowdsensing,most location privacy protection studies do not consider the temporal correlations between locations,so they are vulnerable to various inference attacks,and there is the problem of low data availability.In order to solve the above problems,this paper proposes a dynamic differential location privacy data publishing framework(DDLP)that protects privacy while publishing locations continuously.Firstly,the corresponding Markov transition matrices are established according to different times of historical trajectories,and then the protection location set is generated based on the current location at each timestamp.Moreover,using the exponential mechanism in differential privacy perturbs the true location by designing the utility function.Finally,experiments on the real-world trajectory dataset show that our method not only provides strong privacy guarantees,but also outperforms existing methods in terms of data availability and computational efficiency.
文摘针对风机偏航转速传感器在长期运行中受偏航旋转工况影响易出现供电不连续与电压波动的问题,开展基于有限电源(Limited Power Source,LPS)冗余供电的稳定性改造应用研究。通过在传感器供电侧引入LPS冗余供电方式,从供电连续性增强、供电波动抑制及转速信号稳定输出3个方面分析LPS冗余供电在稳定性改造方面的应用,并结合工程实例对改造效果进行对比分析。结果表明,引入LPS冗余供电能够有效提升偏航转速传感器运行稳定性,具有良好的工程应用价值。
文摘Dysregulated inflammation and multi-organ failure are hallmarks of sepsis,a potentially fatal illness for which there are currently no effective treatments.Fatty acid-binding protein(A-FABP)has been identified in recent research as a crucial mediator of the inflammatory pathways underlying sepsis.In this study,we used a murine model of lipopolysaccharide(LPS)-induced endotoxemia to assess the therapeutic potential of 6H2,a monoclonal antibody that targets A-FABP.In comparison to untreated septic mice,6H2 treatment significantly increased survival rates,decreased histopathological damage in the liver,lungs,kidneys,and heart,and reduced systemic inflammation.According to biochemical analyses,6H2 treatment decreased circulating levels of A-FABP,and this was associated with a reduction in inflammatory markers.These results indicate that A-FABP inhibition is a potentially effective treatment approach for sepsis,with 6H2 demonstrating strong therapeutic efficacy.
文摘Amidst evolving user behavior driven by the development of the internet,enhancing the operational quality of trade publishing knowledge service platforms has become a significant challenge for publishing institutions.To address this issue,this paper employs a combined approach of theoretical analysis and case study,introducing the SICAS(Sense-Interest-Connection-Action-Share)user consumption behavior analysis model and selecting“CITIC Academy”as the case study subject.It systematically examines and summarizes the platform’s operational practices and specific strategies,aiming to offer strategic insights and practical references for the operational improvement and sustainable,high-quality development of trade publishing knowledge service platforms.