The uptake of Radium-226,Radium-228 and potassium-40 by tomato plants as the effect of irrigation with thermal water was studied as pot experiments.Tomato seedlings were grown in 7 L pots filled with four different so...The uptake of Radium-226,Radium-228 and potassium-40 by tomato plants as the effect of irrigation with thermal water was studied as pot experiments.Tomato seedlings were grown in 7 L pots filled with four different soil textural classes collected from different locations;silt clay soil(SZ1)and sandy clay loam(SZ2)collected from Zara area at Jordan Valley with 226Ra activity 392(SZ2)and 5350(SZ1)Bq∙kg^(-1).Two control soils also were used;clay loamy soil(SW)and sandy soil(SSa)were collected from Amman with 226Ra activity about 20 Bq∙kg^(-1) for SW 8.3 Bq∙kg^(-1).Half of the treatments were irrigated with ther-mal water while the other half were irrigated with non-thermal water.The av-erage Transfer Factor(TF)for 226Ra values ranged from 0.002 to 0.91 in tomato fruits while in vegetative parts ranging from 0.003 to 2.54(stems)and from 0.014,to 4.96(leaves)as a response to irrigation with thermal water.Radium-228 was just detected in tomato leaves that were grown in sandy soil(SSa).High TF was observed for ^(40)K in tomato fruits(8.2 to 133.7)as compared to leaves(1.2 to 16.0)and in stems(1.9 to 11.3).The highest TF values for both 226Ra and ^(40)K were observed in sandy soil.Analysis indicated that source of irrigation water and soil factors affects 226Ra activity in plant tissues while ^(40)K is only af-fected by its concentration in soil.Although the pot experiment offers con-trolled conditions for testing,it does not fully replicate field conditions where root depth,soil heterogeneity,and environmental interactions may influence radionuclide uptake.Therefore,the findings should be interpreted with this limitation in mind.展开更多
目的探究CDC40在结直肠癌组织中的表达特征及其与临床病理特征的相关性,为结直肠癌的早期诊断、靶向治疗及预后评估提供依据。方法采用免疫组织化学染色评估70例结直肠癌患者组织中CDC40表达水平,并分析其与临床病理特征关系;运用R软件...目的探究CDC40在结直肠癌组织中的表达特征及其与临床病理特征的相关性,为结直肠癌的早期诊断、靶向治疗及预后评估提供依据。方法采用免疫组织化学染色评估70例结直肠癌患者组织中CDC40表达水平,并分析其与临床病理特征关系;运用R软件包进行生存曲线和多因素预后分析;使用结直肠癌细胞系SW620和Caco-2进行细胞培养、CDC40质粒转染、细胞增殖实验、蛋白质印迹及裸鼠成瘤实验,以验证CDC40对细胞增殖的影响,实验数据采用IBM SPSS Statistics Version 22软件进行统计分析。结果70例患者中CDC40高表达组占51.4%,其表达高低与肿瘤分化程度、T分期、淋巴结转移及增殖指数Ki67水平相关,与性别、年龄、远处转移无关;多因素和单因素生存分析显示CDC40高表达与患者更差的生存预后相关;体外实验中过表达CDC40促进结直肠癌细胞系增殖;裸鼠成瘤实验表明过表达CDC40促进肿瘤生长。结论CDC40在结直肠癌发生发展中起重要作用,可作为潜在分子标志物和治疗靶点。展开更多
文摘The uptake of Radium-226,Radium-228 and potassium-40 by tomato plants as the effect of irrigation with thermal water was studied as pot experiments.Tomato seedlings were grown in 7 L pots filled with four different soil textural classes collected from different locations;silt clay soil(SZ1)and sandy clay loam(SZ2)collected from Zara area at Jordan Valley with 226Ra activity 392(SZ2)and 5350(SZ1)Bq∙kg^(-1).Two control soils also were used;clay loamy soil(SW)and sandy soil(SSa)were collected from Amman with 226Ra activity about 20 Bq∙kg^(-1) for SW 8.3 Bq∙kg^(-1).Half of the treatments were irrigated with ther-mal water while the other half were irrigated with non-thermal water.The av-erage Transfer Factor(TF)for 226Ra values ranged from 0.002 to 0.91 in tomato fruits while in vegetative parts ranging from 0.003 to 2.54(stems)and from 0.014,to 4.96(leaves)as a response to irrigation with thermal water.Radium-228 was just detected in tomato leaves that were grown in sandy soil(SSa).High TF was observed for ^(40)K in tomato fruits(8.2 to 133.7)as compared to leaves(1.2 to 16.0)and in stems(1.9 to 11.3).The highest TF values for both 226Ra and ^(40)K were observed in sandy soil.Analysis indicated that source of irrigation water and soil factors affects 226Ra activity in plant tissues while ^(40)K is only af-fected by its concentration in soil.Although the pot experiment offers con-trolled conditions for testing,it does not fully replicate field conditions where root depth,soil heterogeneity,and environmental interactions may influence radionuclide uptake.Therefore,the findings should be interpreted with this limitation in mind.
文摘目的探究CDC40在结直肠癌组织中的表达特征及其与临床病理特征的相关性,为结直肠癌的早期诊断、靶向治疗及预后评估提供依据。方法采用免疫组织化学染色评估70例结直肠癌患者组织中CDC40表达水平,并分析其与临床病理特征关系;运用R软件包进行生存曲线和多因素预后分析;使用结直肠癌细胞系SW620和Caco-2进行细胞培养、CDC40质粒转染、细胞增殖实验、蛋白质印迹及裸鼠成瘤实验,以验证CDC40对细胞增殖的影响,实验数据采用IBM SPSS Statistics Version 22软件进行统计分析。结果70例患者中CDC40高表达组占51.4%,其表达高低与肿瘤分化程度、T分期、淋巴结转移及增殖指数Ki67水平相关,与性别、年龄、远处转移无关;多因素和单因素生存分析显示CDC40高表达与患者更差的生存预后相关;体外实验中过表达CDC40促进结直肠癌细胞系增殖;裸鼠成瘤实验表明过表达CDC40促进肿瘤生长。结论CDC40在结直肠癌发生发展中起重要作用,可作为潜在分子标志物和治疗靶点。
