Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent d...Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent data in the field of tumor cell therapy in China,the patent map method was used to construct a scientific technical information analysis model.Then,the technical status of new drug research and development in this field was explored to identify technical opportunities.Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage.The technical innovation regions are mainly distributed in the east and innovative entities are enterprises.Technology hotspots are concentrated in areas such as A61P35,C12N5,and the patented technical efficacy is high.Besides,the technical research and development opportunities identified are closely related to the background in this field.To better promote the development of the industry,enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile,they should pay attention to technical efficacy analysis to identify more technical opportunities,thereby effectively guiding innovation strategic decisions.展开更多
Objective To study the patent map and the relevant theories of the patent development of biopharmaceutical industry for conducting a comprehensive and in-depth analysis of the problems in patent application in Liaonin...Objective To study the patent map and the relevant theories of the patent development of biopharmaceutical industry for conducting a comprehensive and in-depth analysis of the problems in patent application in Liaoning biopharmaceutical industry.Methods Literature review,information visualization method,empirical analysis method and comparative analysis method were used to research the problems in the patent application.Results and Conclusion While developing biopharmaceutical industry,Liaoning provincial government should strengthen the protection of pharmaceutical patents,creating a new R&D mode of“university+research institutes+enterprises+individuals”to broaden the scope of technical fields.Then,its biopharmaceutical industry will be developed in an all-round way.Besides,it should closely follow the national development direction so that the biopharmaceutical industry in Liaoning Province will have a bright future.展开更多
Purpose： First, to review the state-of-the-art in patent citation analysis, particularly characteristics of patent citations to scientific literature （scientific non-patent references, SNPRs）. Second, to present a ...Purpose： First, to review the state-of-the-art in patent citation analysis, particularly characteristics of patent citations to scientific literature （scientific non-patent references, SNPRs）. Second, to present a novel mapping approach to identify technology-relevant research based on the papers cited by and referring to the SNPRs. Design/methodology/approach： In the review part we discuss the context of SNPRs such as the time lags between scientific achievements and inventions. Also patent-to-patent citation is addressed particularly because this type of patent citation analysis is a major element in the assessment of the economic value of patents. We also review the research on the role of universities and researchers in technological development, with important issues such as universities as sources of technological knowledge and inventor-author relations. We conclude the review part of this paper with an overview of recent research on mapping and network analysis of the science and technology interface and of technological progress in interaction with science. In the second part we apply new techniques for the direct visualization of the cited and citing relations of SNPRs, the mapping of the landscape around SNPRs by bibliographic coupling and co-citation analysis, and the mapping of the conceptual environment of SNPRs by keyword co-occurrence analysis. Findings： We discuss several properties of SNPRs. Only a small minority of publications covered by the Web of Science or Scopus are cited by patents, about 3%-4%. However, for publications based on university-industry collaboration the number of SNPRs is considerably higher, around 15%. The proposed mapping methodology based on a ＂second order SNPR approach＂ enables a better assessment of the technological relevance of research. Research limitations： The main limitation is that a more advanced merging of patent and publication data, in particular unification of author and inventor names, in still a necessity. Practical implications： The proposed mapping methodology enables the creation of a database of technology-relevant papers （TRPs）. In a bibliometric assessment the publications of research groups, research programs or institutes can be matched with the TRPs and thus the extent to which the work of groups, programs or institutes are relevant for technological development can be measured. Originality/value： The review part examines a wide range of findings in the research of patent citation analysis. The mapping approach to identify a broad range of technologyrelevant papers is novel and offers new opportunities in research evaluation practices.展开更多
In view of the lack of patent big data in research on technology foresight in the industrial robot field, this paper introduces an improved method based on patent mining and knowledge map. Firstly, SAO structure is ex...In view of the lack of patent big data in research on technology foresight in the industrial robot field, this paper introduces an improved method based on patent mining and knowledge map. Firstly, SAO structure is extracted from selected patents, secondly, the similarity between patents is calculated based on extracted SAO structure, thirdly, patent network and patent map are drawn based on calculated patent similarity matrix, technology evolution process and future trends of industrial robot are summarized from patent network, and future potential technology opportunities are predicted based on technological vacancies identified from patent map. Finally, this paper identifies six key technical areas and four potential technical opportunities in the field of the industrial robot.展开更多
目的运用文献计量学方法分析贝母属Fritillaria植物的研究现状与发展趋势,并通过专利分析得到贝母属植物的成果转化情况,为未来的开发应用提供方向参考。方法在中国知网数据库、万方数据库、维普数据库、Web of Science核心合集数据库,...目的运用文献计量学方法分析贝母属Fritillaria植物的研究现状与发展趋势,并通过专利分析得到贝母属植物的成果转化情况,为未来的开发应用提供方向参考。方法在中国知网数据库、万方数据库、维普数据库、Web of Science核心合集数据库,以贝母和Fritillaria为主题检索词收集相关文献,导入NoteExpress文献管理软件中进行查重、筛选和格式转换;使用Excel、CiteSpace、VOSviewer软件对中英文文献的年度发文趋势、合作网络、研究热点等进行可视化分析。通过Incopat专利数据库从专利申请趋势、专利申请地域分布、专利申请人等方面对贝母属植物专利申请情况进行分析。结果共纳入符合标准的中文文献1511篇,英文文献805篇。贝母属发文量大体呈现上升的趋势,共有56个国家参与贝母属的研究,发文国家以中国为主。英文文献涉及学科以植物科学为主。中、英文发文量最多的作者分别是周浓和Li Ping,最多的机构分别是中国中医科学院和Chinese Academy of Sciences(中国科学院),部分发文作者间已形成研究团队,发文机构间的合作关系较分散。基于Incopat专利数据库检索得到专利数据10292件,国内专利有9980件,占比96.97%,占据绝对的主导地位。结论贝母属植物的研究处于不断拓展与上升阶段,其研究核心物种为浙贝母和川贝母,热点方向为生物碱等活性成分、药理作用与分子机制、生长栽培与资源保护等。贝母属植物专利在全球分布差距明显,我国的专利申请量占据绝对主导地位,但当前仍面临申请活跃度不足、有效率较低、技术构成单一以及竞争力不强等问题。展开更多
钻井作为油气勘探开发的核心环节之一,随着大数据、人工智能技术在钻井领域的深入应用,智能钻井技术不断取得突破。以德温特创新索引国际专利数据库(DII)为数据来源,利用Derwent Data Analyzer(DDA)、Derwent Innovation(DI)等专利分析...钻井作为油气勘探开发的核心环节之一,随着大数据、人工智能技术在钻井领域的深入应用,智能钻井技术不断取得突破。以德温特创新索引国际专利数据库(DII)为数据来源,利用Derwent Data Analyzer(DDA)、Derwent Innovation(DI)等专利分析工具和平台,对智能钻井领域的专利申请进行了系统分析。结果表明,智能钻井领域专利申请主要集中在中国、美国和加拿大,但美国核心专利数量占据绝对优势。主要研发机构包括中国石油、中国石化、中海油、西南石油大学、哈里伯顿能源服务公司等。技术布局主要集中在利用旋转钻井、测试操作和设备、海洋钻井结构和设备、其他钻井方法和设备、钻井液、打捞和回收工具、缆索钻井等。展开更多
为了探析玉竹的研究现状、热点和发展趋势,为进一步开展研究提供参考,运用CiteSpace软件对中国知网(China National Knowledge Infrastructure,CNKI)和科学网(Web of Science,WOS)核心集数据库中玉竹相关文献的发文量、关键词、作者、...为了探析玉竹的研究现状、热点和发展趋势,为进一步开展研究提供参考,运用CiteSpace软件对中国知网(China National Knowledge Infrastructure,CNKI)和科学网(Web of Science,WOS)核心集数据库中玉竹相关文献的发文量、关键词、作者、机构、国家等进行可视化分析,并结合IncoPat专利数据库分析玉竹相关专利的申请趋势、全球地域分布、申请人、总体技术构成。结果显示:玉竹相关文献的年发文量整体呈上升趋势,中英文发文量最多的作者分别为刘塔斯(19篇)、金晨钟(6篇)和胡一鸿(6篇),发文量最多的机构分别为吉林农业科技学院(37篇)、湖南中医药大学(7篇)和天津中医药大学(7篇)及湖南人文科技学院(7篇);中英文关键词显示,玉竹的研究热点集中于化学成分、药理作用和组方规律。目前玉竹专利处于下行趋势,以中国申请的专利数量最多,申请人类型以企业为主,技术构成以玉竹的组方配伍为主。综合分析,化学成分、药理作用和组方规律等是目前玉竹的研究热点,也是未来的研究趋势,特别是主要药效成分多糖和甾体皂苷及其抗氧化和抗肿瘤作用;玉竹专利方面则应加强企业与科研机构之间的交流,进行产学研合作,聚焦新技术、新方法的突破。展开更多
文摘Objective To analyze the technical information in the field of tumor cell therapy in China,and to provide reference for identifying technical trends and predicting technical opportunities.Methods Based on the patent data in the field of tumor cell therapy in China,the patent map method was used to construct a scientific technical information analysis model.Then,the technical status of new drug research and development in this field was explored to identify technical opportunities.Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage.The technical innovation regions are mainly distributed in the east and innovative entities are enterprises.Technology hotspots are concentrated in areas such as A61P35,C12N5,and the patented technical efficacy is high.Besides,the technical research and development opportunities identified are closely related to the background in this field.To better promote the development of the industry,enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile,they should pay attention to technical efficacy analysis to identify more technical opportunities,thereby effectively guiding innovation strategic decisions.
文摘Objective To study the patent map and the relevant theories of the patent development of biopharmaceutical industry for conducting a comprehensive and in-depth analysis of the problems in patent application in Liaoning biopharmaceutical industry.Methods Literature review,information visualization method,empirical analysis method and comparative analysis method were used to research the problems in the patent application.Results and Conclusion While developing biopharmaceutical industry,Liaoning provincial government should strengthen the protection of pharmaceutical patents,creating a new R&D mode of“university+research institutes+enterprises+individuals”to broaden the scope of technical fields.Then,its biopharmaceutical industry will be developed in an all-round way.Besides,it should closely follow the national development direction so that the biopharmaceutical industry in Liaoning Province will have a bright future.
文摘Purpose： First, to review the state-of-the-art in patent citation analysis, particularly characteristics of patent citations to scientific literature （scientific non-patent references, SNPRs）. Second, to present a novel mapping approach to identify technology-relevant research based on the papers cited by and referring to the SNPRs. Design/methodology/approach： In the review part we discuss the context of SNPRs such as the time lags between scientific achievements and inventions. Also patent-to-patent citation is addressed particularly because this type of patent citation analysis is a major element in the assessment of the economic value of patents. We also review the research on the role of universities and researchers in technological development, with important issues such as universities as sources of technological knowledge and inventor-author relations. We conclude the review part of this paper with an overview of recent research on mapping and network analysis of the science and technology interface and of technological progress in interaction with science. In the second part we apply new techniques for the direct visualization of the cited and citing relations of SNPRs, the mapping of the landscape around SNPRs by bibliographic coupling and co-citation analysis, and the mapping of the conceptual environment of SNPRs by keyword co-occurrence analysis. Findings： We discuss several properties of SNPRs. Only a small minority of publications covered by the Web of Science or Scopus are cited by patents, about 3%-4%. However, for publications based on university-industry collaboration the number of SNPRs is considerably higher, around 15%. The proposed mapping methodology based on a ＂second order SNPR approach＂ enables a better assessment of the technological relevance of research. Research limitations： The main limitation is that a more advanced merging of patent and publication data, in particular unification of author and inventor names, in still a necessity. Practical implications： The proposed mapping methodology enables the creation of a database of technology-relevant papers （TRPs）. In a bibliometric assessment the publications of research groups, research programs or institutes can be matched with the TRPs and thus the extent to which the work of groups, programs or institutes are relevant for technological development can be measured. Originality/value： The review part examines a wide range of findings in the research of patent citation analysis. The mapping approach to identify a broad range of technologyrelevant papers is novel and offers new opportunities in research evaluation practices.
文摘In view of the lack of patent big data in research on technology foresight in the industrial robot field, this paper introduces an improved method based on patent mining and knowledge map. Firstly, SAO structure is extracted from selected patents, secondly, the similarity between patents is calculated based on extracted SAO structure, thirdly, patent network and patent map are drawn based on calculated patent similarity matrix, technology evolution process and future trends of industrial robot are summarized from patent network, and future potential technology opportunities are predicted based on technological vacancies identified from patent map. Finally, this paper identifies six key technical areas and four potential technical opportunities in the field of the industrial robot.
文摘运用证据图系统检索与梳理口服中成药治疗脑出血(intracerebral hemorrhage,ICH)的临床研究证据,了解该领域现有证据分布及质量。通过检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Web of Science、EMbase、Cochrane Library数据库,建库至2024年7月5日发表的相关文献,采用图、表结合文字形式展示数据分布特征。共检索到35种中成药,纳入261篇文献,将中成药的基本信息、发文趋势、中医证型、干预措施、结局指标等进行对比和分析,并对文献方法学质量进行评价。结果显示,治疗ICH的中成药临床定位宽泛;未充分体现中医优势与特色;安全性信息尚不完善;结局指标评价方面评价标准不统一,对认知功能、心理学方面关注略显不足;文献方法学质量较低。建议在今后的临床研究中,规范试验设计,突出中医特色;将中医证候评价作为重要结局指标,并统一评价标准,多关注患者认知功能与心理学情况;建议治疗ICH中成药的上市许可持有人按照国家药品监督管理局相关要求,规范临床定位,修订完善说明书中安全性信息;提高医保目录中甲类中成药占比,合理配置有限的医疗资源。
文摘目的运用文献计量学方法分析贝母属Fritillaria植物的研究现状与发展趋势,并通过专利分析得到贝母属植物的成果转化情况,为未来的开发应用提供方向参考。方法在中国知网数据库、万方数据库、维普数据库、Web of Science核心合集数据库,以贝母和Fritillaria为主题检索词收集相关文献,导入NoteExpress文献管理软件中进行查重、筛选和格式转换;使用Excel、CiteSpace、VOSviewer软件对中英文文献的年度发文趋势、合作网络、研究热点等进行可视化分析。通过Incopat专利数据库从专利申请趋势、专利申请地域分布、专利申请人等方面对贝母属植物专利申请情况进行分析。结果共纳入符合标准的中文文献1511篇,英文文献805篇。贝母属发文量大体呈现上升的趋势,共有56个国家参与贝母属的研究,发文国家以中国为主。英文文献涉及学科以植物科学为主。中、英文发文量最多的作者分别是周浓和Li Ping,最多的机构分别是中国中医科学院和Chinese Academy of Sciences(中国科学院),部分发文作者间已形成研究团队,发文机构间的合作关系较分散。基于Incopat专利数据库检索得到专利数据10292件,国内专利有9980件,占比96.97%,占据绝对的主导地位。结论贝母属植物的研究处于不断拓展与上升阶段,其研究核心物种为浙贝母和川贝母,热点方向为生物碱等活性成分、药理作用与分子机制、生长栽培与资源保护等。贝母属植物专利在全球分布差距明显,我国的专利申请量占据绝对主导地位,但当前仍面临申请活跃度不足、有效率较低、技术构成单一以及竞争力不强等问题。
文摘钻井作为油气勘探开发的核心环节之一,随着大数据、人工智能技术在钻井领域的深入应用,智能钻井技术不断取得突破。以德温特创新索引国际专利数据库(DII)为数据来源,利用Derwent Data Analyzer(DDA)、Derwent Innovation(DI)等专利分析工具和平台,对智能钻井领域的专利申请进行了系统分析。结果表明,智能钻井领域专利申请主要集中在中国、美国和加拿大,但美国核心专利数量占据绝对优势。主要研发机构包括中国石油、中国石化、中海油、西南石油大学、哈里伯顿能源服务公司等。技术布局主要集中在利用旋转钻井、测试操作和设备、海洋钻井结构和设备、其他钻井方法和设备、钻井液、打捞和回收工具、缆索钻井等。
文摘为了探析玉竹的研究现状、热点和发展趋势,为进一步开展研究提供参考,运用CiteSpace软件对中国知网(China National Knowledge Infrastructure,CNKI)和科学网(Web of Science,WOS)核心集数据库中玉竹相关文献的发文量、关键词、作者、机构、国家等进行可视化分析,并结合IncoPat专利数据库分析玉竹相关专利的申请趋势、全球地域分布、申请人、总体技术构成。结果显示:玉竹相关文献的年发文量整体呈上升趋势,中英文发文量最多的作者分别为刘塔斯(19篇)、金晨钟(6篇)和胡一鸿(6篇),发文量最多的机构分别为吉林农业科技学院(37篇)、湖南中医药大学(7篇)和天津中医药大学(7篇)及湖南人文科技学院(7篇);中英文关键词显示,玉竹的研究热点集中于化学成分、药理作用和组方规律。目前玉竹专利处于下行趋势,以中国申请的专利数量最多,申请人类型以企业为主,技术构成以玉竹的组方配伍为主。综合分析,化学成分、药理作用和组方规律等是目前玉竹的研究热点,也是未来的研究趋势,特别是主要药效成分多糖和甾体皂苷及其抗氧化和抗肿瘤作用;玉竹专利方面则应加强企业与科研机构之间的交流,进行产学研合作,聚焦新技术、新方法的突破。
