Dental implants have restored masticatory function to over 100000000 individuals,yet almost 1000000 implants fail each year due to peri-implantitis,a disease triggered by peri-implant microbial dysbiosis.Our ability t...Dental implants have restored masticatory function to over 100000000 individuals,yet almost 1000000 implants fail each year due to peri-implantitis,a disease triggered by peri-implant microbial dysbiosis.Our ability to prevent and treat peri-implantitis is hampered by a paucity of knowledge of how these biomes are acquired and the factors that engender normobiosis.Therefore,we combined a 3-month interventional study of 15 systemically and periodontally healthy adults with whole genome sequencing,finescale enumeration and graph theoretics to interrogate colonization dynamics in the pristine peri-implant sulcus.We discovered that colonization trajectories of implants differ substantially from adjoining teeth in acquisition of new members and development of functional synergies.Source-tracking algorithms revealed that this niche is initially seeded by bacteria trapped within the coverscrew chamber during implant placement.These pioneer species stably colonize the microbiome and exert a sustained influence on the ecosystem by serving as anchors of influential hubs and by providing functions that enable cell replication and biofilm maturation.Unlike the periodontal microbiome,recruitment of new members to the peri-implant community occurs on nepotistic principles.Maturation is accompanied by a progressive increase in anaerobiosis,however,the predominant functionalities are oxygen-dependent over the 12-weeks.The peri-implant community is easily perturbed following crown placement,but demonstrates remarkable resilience;returning to pre-perturbation states within three weeks.This study highlights important differences in the development of the periodontal and peri-implant ecosystems,and signposts the importance of placing implants in periodontally healthy individuals or following the successful resolution of periodontal disease.展开更多
Peri-implant keratinized mucosa(PIKM)augmentation refers to surgical procedures aimed at increasing the width of PIKM.Consensus reports emphasize the necessity of maintaining a minimum width of PIKM to ensure long-ter...Peri-implant keratinized mucosa(PIKM)augmentation refers to surgical procedures aimed at increasing the width of PIKM.Consensus reports emphasize the necessity of maintaining a minimum width of PIKM to ensure long-term peri-implant health.Currently,several surgical techniques have been validated for their effectiveness in increasing PIKM.However,the selection and application of PIKM augmentation methods may present challenges for dental practitioners due to heterogeneity in surgical techniques,variations in clinical scenarios,and anatomical differences.Therefore,clear guidelines and considerations for PIKM augmentation are needed.This expert consensus focuses on the commonly employed surgical techniques for PIKM augmentation and the factors influencing their selection at second-stage surgery.It aims to establish a standardized framework for assessing,planning,and executing PIKM augmentation procedures,with the goal of offering evidence-based guidance to enhance the predictability and success of PIKM augmentation.展开更多
The warm needling and acupoint injection of medicine are combined to treat scapulo-humeral periarthritis with marked analgesic effect because they have the efficacies of reinforcing defi-ciency and supporting the heal...The warm needling and acupoint injection of medicine are combined to treat scapulo-humeral periarthritis with marked analgesic effect because they have the efficacies of reinforcing defi-ciency and supporting the healthy energy,and eliminating the pathogens ans dredging the meridiansand collaterals.The quick and fair therapeutical effect will be obtained when the needling sensation ispropagated to the focus of disease.展开更多
AIM:To evaluate whether the application of sorafenib during the peri-operative period of liver transplantation improves prognosis in liver cancer patients.METHODS:We searched Pub Med,EMBASE and MEDLINE for eligible ar...AIM:To evaluate whether the application of sorafenib during the peri-operative period of liver transplantation improves prognosis in liver cancer patients.METHODS:We searched Pub Med,EMBASE and MEDLINE for eligible articles.A total of 4 studieswere found that fulfilled the previously agreed-upon standards.We then performed a systematic review and meta-analysis on the enrolled trials that met the inclusion criteria.RESULTS:Out of the 104 studies identified in the database,82 were not clinical experiments,and 18 did not fit the inclusion standards.Among the remaining 4 articles,only 1 was related to the preoperative use of sorafenib,whereas the other 3 were related to its postoperative use.As the heterogeneity among the 4 studies was high,with an I2 of 86%,a randomized effect model was applied to pool the data.The application of sorafenib before liver transplantation had a hazard ratio(HR) of 3.29 with a 95% confidence interval(CI) of 0.33-32.56.The use of sorafenib after liver transplantation had an HR of 1.44(95%CI:0.27-7.71).The overall pooled HR was 1.68(95%CI:0.41-6.91).CONCLUSION:The results showed that the use of sorafenib during the peri-operative period of liver transplantation did not improve patient survival significantly.In fact,sorafenib could even lead to a worse prognosis,as its use may increase the hazard of poor survival.展开更多
Studies on peri urban farming in Zambia have not adequately tackled the issues pertaining to heavy metal contaminated wastewater irrigation farming. The study investigated heavy metal contamination of water, soils and...Studies on peri urban farming in Zambia have not adequately tackled the issues pertaining to heavy metal contaminated wastewater irrigation farming. The study investigated heavy metal contamination of water, soils and crops at two peri urban areas in Zambia. Two study sites were New Farm Extension in Mufulira Town in the Copperbelt Province and Chilumba Gardens in Kafue Town in Lusaka Province. The heavy metals investigated were lead, copper, cobalt, nickel and chromium. These heavy metals were found to be higher than acceptable limits in wastewater used to irrigate crops and there are potential human health risks associated with consumption of heavy metal contaminated food crops which have implications on the livelihoods of people. Samples of water, soil and crops were collected and analysed for lead (Pb), copper (Cu), chromium (Cr), cobalt (Co) and nickel (Ni) using the Atomic Absorption Spectrometer (AAS). The data on heavy metals was analysed using mean, standard error and T-test. The results indicated that the levels of heavy metals in wastewater, soil and food crops were above acceptable limits at two study sites. It can be concluded that there was heavy metal contamination of wastewater, soil and food crops at the two peri-urban areas in Zambia. The study highlighted the actual levels of heavy metal contaminant uptake in food crops consumed by the peri urban population. The information from this study can be used by the relevant authorities to develop appropriate measures for monitoring and control of heavy metal contamination in wastewater irrigation farming systems in peri urban areas inZambia.展开更多
Introduction: Perioperative hypothermia in cardiac surgery is associated with adverse outcome. The aim of this investigation was to study whether an underbody forced-air warming blanket during coronary artery bypass g...Introduction: Perioperative hypothermia in cardiac surgery is associated with adverse outcome. The aim of this investigation was to study whether an underbody forced-air warming blanket during coronary artery bypass graft surgery with normothermic cardiopulmonary bypass can prevent postoperative hypothermia. Methods: After Medical Ethics Committee approval, 60 low-risk cardiac surgery patients at random were assigned into a group that received standard thermal care management (control group n = 30) and a group that received the underbody forced-air warming system plus the standard thermal care (intervention group n = 30). Results: The temperature after-drop from the end of cardiopulmonary bypass to arrival in the ICU was less in the intervention group versus control group (0.4°C ± 0.3°C vs 0.6°C ± 0.4°C;P = 0.027). Out of the intervention group, 27 patients arrived in the ICU with a bladder temperature ? 36°C (90%) as compared to 14 patients (46.7%) from the control group (P < 0.001). The peripheral temperature was significantly higher in the intervention group as compared to the control group (P < 0.001). Conclusions: A full underbody forced-air warming blanket prevents postoperative hypothermia in normothermic coronary artery bypass graft surgery patients.展开更多
BACKGROUND Percutaneous drainage(PCD)and endoscopic approaches have largely replaced surgical drainage as the initial approach for(peri)pancreatic fluid collections(PFC)s,while complications associated with endoscopic...BACKGROUND Percutaneous drainage(PCD)and endoscopic approaches have largely replaced surgical drainage as the initial approach for(peri)pancreatic fluid collections(PFC)s,while complications associated with endoscopic stent implantation are common.AIM To introduce a novel endoscopic therapy named endoscopic transgastric fenestration(ETGF),which involves resection of tissue by endoscopic accessory between gastric and PFCs without stent implantation,and to evaluate its efficacy and safety compared with PCD for the management of PFCs adjacent to the gastric wall.METHODS Patients diagnosed with PFCs adjacent to the gastric wall and who subsequently received ETGF or PCD were restrospectively enrolled.Indications for intervention were consistent with related guidelines.We analyzed patients baseline characteristics,technical and clinical success rate,recurrence and reintervention rate,procedure-related complications and adverse events.RESULTS Seventy-two eligible patients were retrospectively identified(ETGF=34,PCD=38)from October 2017 to May 2021.Patients in the ETGF group had a significantly higher clinical success rate than those in the PCD group(97.1 vs 76.3%,P=0.01).There were no statistically significant differences regarding recurrence,reintervention and incidence of complication between the two groups.While long-term catheter drainage was very common in the PCD group.CONCLUSION Compared with PCD,ETGF has a higher clinical success rate in the management of PFCs adjacent to the gastric wall.ETGF is an alternative effective strategy for the treatment of PFCs adjacent to the gastric wall.展开更多
Pericardiocentesis is a common therapeutic procedure for pericardial tamponade due to pericardial effusion as well as a diagnostic procedure to obtain fluid for cytopathologic examination.Standard methods include ultr...Pericardiocentesis is a common therapeutic procedure for pericardial tamponade due to pericardial effusion as well as a diagnostic procedure to obtain fluid for cytopathologic examination.Standard methods include ultrasound or fluoroscopic guidance,which generally result in high success rates(over 95%).[1,2].The complication rate of pericardiocentesis is low with reported incidences of l%-2%.[3]In the past,the most common indications for pericardiocentesis include uremia,tuberculous pericarditis or malignant pericardial effusions.However,with the increasing number of catheter-based interventional cardiac procedures,iatrogenic pericardial effusions are becoming more frequent[4-6].展开更多
Epi continental arc system is a series of arcuate structures along coastlines of the mainland and behind the island arc system on the margin of the Northwest peri Pacific region. Epi continental arc is similar to t...Epi continental arc system is a series of arcuate structures along coastlines of the mainland and behind the island arc system on the margin of the Northwest peri Pacific region. Epi continental arc is similar to the island arc in geometery and kinematics, but it was characterised by an arcuate fracture zone and compensated front sag, basic volcanic activity, shallow earthquake belt and the latest active tectonics. The eastern China continent is dominated by the coastal epi continental arc of Southeast China. Its front arc is situated along the coastline of Zhejiang, Fujian and eastern Guangdong provinces which is convex to SE. The left NW trending flank extended along the NW trending coast line of northern Jiangsu and traversed Shangdong Peninsula to northern Hebei and Shanxi provinces; and the right E W trending flank along the western Guangdong, southern Guangxi, northern Hainan coastlines extended to northern Hanoi. This arc controlls activities of the most modern intense earthquakes in eastern China continents. The compressing thrust type earthquakes occurred along the front arc, especially the 'collison belt', and the strike slip type earthquakes along the both flanks sinistral and dextral strike slip faults respectively. Earthquakes of epi continental arc type is characterised by segmentation in space and periodicity in time.展开更多
The perioperative management of 81 cases with pheochromocytoma was reviewed including blood pressure and arrhythmia control, blood volume expansion, patient′s general condition improvement and vital signs monitoring....The perioperative management of 81 cases with pheochromocytoma was reviewed including blood pressure and arrhythmia control, blood volume expansion, patient′s general condition improvement and vital signs monitoring. It was stressed that pre and intra operative management was of prime importance in the treatment of pheochromocytoma.展开更多
<strong>Objective:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""> This work aimed to evaluate the epidemiological clinical aspects and evolu...<strong>Objective:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""> This work aimed to evaluate the epidemiological clinical aspects and evolutionary aspects of peri partum cardiomyopathy (PPCM) in the cardiology department of the CHU Point G. <b>Materials and Methods:</b> This was a descriptive cross-sectional study from </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">0</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">1 January 2019 to 31 December 2019, including all patients admitted for heart failure during this period.<b> Results:</b> The study involved 40 patients out of 1187 admissions, a hospital prevalence of PPCM was 3.36%. The average age was 26 years plus or minus 7 years with extremes of 16 years and 38 years. The age group between 16 and 20 years was the most represented with 32.5% of cases. Housewives were in the majority with 87.6%;residing in rural areas 62.5%, with a low socio-economic standard of living 32.5% of cases. Multiparous in our context were dominant 42.5%, followed by pauci pares and primiparous with 32.5% and 25% frequency respectively. All our patients, 100% had their first symptom after childbirth, functional signs were dominated by dyspnea of effort present in 100% of patients, followed cough (40%) and chest pain (27.5%). On physical examination there was Tachycardia in 82.5%, Galop B3 (45%) and auscultatory arrhythmia in 5%. Signs of pulmonary condensation (82.5%) and pleural fluid effusion (25%). Hepatomegaly was present in 72.5% of patients. It was overall heart failure in 72.5% of cases. On the electrocardiogram there was sinus tachycardia (75%) and atrial fibrillation arrhythmia (5%). On cardiac Doppler ultrasound the left ventricle was dilated with a low systolic ejection fraction in 100% of patients, the four cavities were dilated in 32.5%, a left intraventricular thrombus in 7.5% of cases and a pericardial fluid effusion in 5% of cases. Biology noted anemia in 22.5% of patients. Treatment was classic for heart failure. The course was punctuated by complications in 42.5% of cases, such as thromboembolic disease (22.5%), ischemic stroke (12.5%), complete arrhythmia by atrial fibrillation (ACFA 5%) and cardiogenic shock (2.5%). Hospital mortality was 7.5% with 67% of deaths observed in the 16</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">-</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">22 age group. </span><span style="white-space:normal;font-size:10pt;font-family:;" "=""><b>Conclusion:</b> PPCM is a common sub-Saharan pathology, low socioeconomic status, young age and multiparity were factors dominant in our context.</span>展开更多
Objective: to study the practical value of rapid rehabilitation nursing for patients undergoing radical prostatectomy. Methods: the control group received routine nursing. The rehabilitation group received rapid rehab...Objective: to study the practical value of rapid rehabilitation nursing for patients undergoing radical prostatectomy. Methods: the control group received routine nursing. The rehabilitation group received rapid rehabilitation nursing. Results: all indexes of rehabilitation group were better than those of control group (P<0.05). Conclusion: rapid rehabilitation nursing has better nursing effect. It is suggested to use it for reference in nursing work.展开更多
基金supported by National Institutes of Health R03DE027492 to Shareef Dabdoubsupported by National Institutes of Health,project number 7R01DE027857-06supported by National Institutes of Health R56DE033913 awarded to Purnima Kumar.
文摘Dental implants have restored masticatory function to over 100000000 individuals,yet almost 1000000 implants fail each year due to peri-implantitis,a disease triggered by peri-implant microbial dysbiosis.Our ability to prevent and treat peri-implantitis is hampered by a paucity of knowledge of how these biomes are acquired and the factors that engender normobiosis.Therefore,we combined a 3-month interventional study of 15 systemically and periodontally healthy adults with whole genome sequencing,finescale enumeration and graph theoretics to interrogate colonization dynamics in the pristine peri-implant sulcus.We discovered that colonization trajectories of implants differ substantially from adjoining teeth in acquisition of new members and development of functional synergies.Source-tracking algorithms revealed that this niche is initially seeded by bacteria trapped within the coverscrew chamber during implant placement.These pioneer species stably colonize the microbiome and exert a sustained influence on the ecosystem by serving as anchors of influential hubs and by providing functions that enable cell replication and biofilm maturation.Unlike the periodontal microbiome,recruitment of new members to the peri-implant community occurs on nepotistic principles.Maturation is accompanied by a progressive increase in anaerobiosis,however,the predominant functionalities are oxygen-dependent over the 12-weeks.The peri-implant community is easily perturbed following crown placement,but demonstrates remarkable resilience;returning to pre-perturbation states within three weeks.This study highlights important differences in the development of the periodontal and peri-implant ecosystems,and signposts the importance of placing implants in periodontally healthy individuals or following the successful resolution of periodontal disease.
基金supported by the Natural Science Foundation of Sichuan Province(grant number:25NSFSC0265).
文摘Peri-implant keratinized mucosa(PIKM)augmentation refers to surgical procedures aimed at increasing the width of PIKM.Consensus reports emphasize the necessity of maintaining a minimum width of PIKM to ensure long-term peri-implant health.Currently,several surgical techniques have been validated for their effectiveness in increasing PIKM.However,the selection and application of PIKM augmentation methods may present challenges for dental practitioners due to heterogeneity in surgical techniques,variations in clinical scenarios,and anatomical differences.Therefore,clear guidelines and considerations for PIKM augmentation are needed.This expert consensus focuses on the commonly employed surgical techniques for PIKM augmentation and the factors influencing their selection at second-stage surgery.It aims to establish a standardized framework for assessing,planning,and executing PIKM augmentation procedures,with the goal of offering evidence-based guidance to enhance the predictability and success of PIKM augmentation.
文摘The warm needling and acupoint injection of medicine are combined to treat scapulo-humeral periarthritis with marked analgesic effect because they have the efficacies of reinforcing defi-ciency and supporting the healthy energy,and eliminating the pathogens ans dredging the meridiansand collaterals.The quick and fair therapeutical effect will be obtained when the needling sensation ispropagated to the focus of disease.
基金Supported by National Natural Science Foundation of China,No.81172349 and No.30872491
文摘AIM:To evaluate whether the application of sorafenib during the peri-operative period of liver transplantation improves prognosis in liver cancer patients.METHODS:We searched Pub Med,EMBASE and MEDLINE for eligible articles.A total of 4 studieswere found that fulfilled the previously agreed-upon standards.We then performed a systematic review and meta-analysis on the enrolled trials that met the inclusion criteria.RESULTS:Out of the 104 studies identified in the database,82 were not clinical experiments,and 18 did not fit the inclusion standards.Among the remaining 4 articles,only 1 was related to the preoperative use of sorafenib,whereas the other 3 were related to its postoperative use.As the heterogeneity among the 4 studies was high,with an I2 of 86%,a randomized effect model was applied to pool the data.The application of sorafenib before liver transplantation had a hazard ratio(HR) of 3.29 with a 95% confidence interval(CI) of 0.33-32.56.The use of sorafenib after liver transplantation had an HR of 1.44(95%CI:0.27-7.71).The overall pooled HR was 1.68(95%CI:0.41-6.91).CONCLUSION:The results showed that the use of sorafenib during the peri-operative period of liver transplantation did not improve patient survival significantly.In fact,sorafenib could even lead to a worse prognosis,as its use may increase the hazard of poor survival.
文摘Studies on peri urban farming in Zambia have not adequately tackled the issues pertaining to heavy metal contaminated wastewater irrigation farming. The study investigated heavy metal contamination of water, soils and crops at two peri urban areas in Zambia. Two study sites were New Farm Extension in Mufulira Town in the Copperbelt Province and Chilumba Gardens in Kafue Town in Lusaka Province. The heavy metals investigated were lead, copper, cobalt, nickel and chromium. These heavy metals were found to be higher than acceptable limits in wastewater used to irrigate crops and there are potential human health risks associated with consumption of heavy metal contaminated food crops which have implications on the livelihoods of people. Samples of water, soil and crops were collected and analysed for lead (Pb), copper (Cu), chromium (Cr), cobalt (Co) and nickel (Ni) using the Atomic Absorption Spectrometer (AAS). The data on heavy metals was analysed using mean, standard error and T-test. The results indicated that the levels of heavy metals in wastewater, soil and food crops were above acceptable limits at two study sites. It can be concluded that there was heavy metal contamination of wastewater, soil and food crops at the two peri-urban areas in Zambia. The study highlighted the actual levels of heavy metal contaminant uptake in food crops consumed by the peri urban population. The information from this study can be used by the relevant authorities to develop appropriate measures for monitoring and control of heavy metal contamination in wastewater irrigation farming systems in peri urban areas inZambia.
文摘Introduction: Perioperative hypothermia in cardiac surgery is associated with adverse outcome. The aim of this investigation was to study whether an underbody forced-air warming blanket during coronary artery bypass graft surgery with normothermic cardiopulmonary bypass can prevent postoperative hypothermia. Methods: After Medical Ethics Committee approval, 60 low-risk cardiac surgery patients at random were assigned into a group that received standard thermal care management (control group n = 30) and a group that received the underbody forced-air warming system plus the standard thermal care (intervention group n = 30). Results: The temperature after-drop from the end of cardiopulmonary bypass to arrival in the ICU was less in the intervention group versus control group (0.4°C ± 0.3°C vs 0.6°C ± 0.4°C;P = 0.027). Out of the intervention group, 27 patients arrived in the ICU with a bladder temperature ? 36°C (90%) as compared to 14 patients (46.7%) from the control group (P < 0.001). The peripheral temperature was significantly higher in the intervention group as compared to the control group (P < 0.001). Conclusions: A full underbody forced-air warming blanket prevents postoperative hypothermia in normothermic coronary artery bypass graft surgery patients.
基金Zhongyuan Talent Program,No.ZYYCYU202012113The Key R and D Program of Henan Province,No.222102310038.
文摘BACKGROUND Percutaneous drainage(PCD)and endoscopic approaches have largely replaced surgical drainage as the initial approach for(peri)pancreatic fluid collections(PFC)s,while complications associated with endoscopic stent implantation are common.AIM To introduce a novel endoscopic therapy named endoscopic transgastric fenestration(ETGF),which involves resection of tissue by endoscopic accessory between gastric and PFCs without stent implantation,and to evaluate its efficacy and safety compared with PCD for the management of PFCs adjacent to the gastric wall.METHODS Patients diagnosed with PFCs adjacent to the gastric wall and who subsequently received ETGF or PCD were restrospectively enrolled.Indications for intervention were consistent with related guidelines.We analyzed patients baseline characteristics,technical and clinical success rate,recurrence and reintervention rate,procedure-related complications and adverse events.RESULTS Seventy-two eligible patients were retrospectively identified(ETGF=34,PCD=38)from October 2017 to May 2021.Patients in the ETGF group had a significantly higher clinical success rate than those in the PCD group(97.1 vs 76.3%,P=0.01).There were no statistically significant differences regarding recurrence,reintervention and incidence of complication between the two groups.While long-term catheter drainage was very common in the PCD group.CONCLUSION Compared with PCD,ETGF has a higher clinical success rate in the management of PFCs adjacent to the gastric wall.ETGF is an alternative effective strategy for the treatment of PFCs adjacent to the gastric wall.
文摘Pericardiocentesis is a common therapeutic procedure for pericardial tamponade due to pericardial effusion as well as a diagnostic procedure to obtain fluid for cytopathologic examination.Standard methods include ultrasound or fluoroscopic guidance,which generally result in high success rates(over 95%).[1,2].The complication rate of pericardiocentesis is low with reported incidences of l%-2%.[3]In the past,the most common indications for pericardiocentesis include uremia,tuberculous pericarditis or malignant pericardial effusions.However,with the increasing number of catheter-based interventional cardiac procedures,iatrogenic pericardial effusions are becoming more frequent[4-6].
文摘Epi continental arc system is a series of arcuate structures along coastlines of the mainland and behind the island arc system on the margin of the Northwest peri Pacific region. Epi continental arc is similar to the island arc in geometery and kinematics, but it was characterised by an arcuate fracture zone and compensated front sag, basic volcanic activity, shallow earthquake belt and the latest active tectonics. The eastern China continent is dominated by the coastal epi continental arc of Southeast China. Its front arc is situated along the coastline of Zhejiang, Fujian and eastern Guangdong provinces which is convex to SE. The left NW trending flank extended along the NW trending coast line of northern Jiangsu and traversed Shangdong Peninsula to northern Hebei and Shanxi provinces; and the right E W trending flank along the western Guangdong, southern Guangxi, northern Hainan coastlines extended to northern Hanoi. This arc controlls activities of the most modern intense earthquakes in eastern China continents. The compressing thrust type earthquakes occurred along the front arc, especially the 'collison belt', and the strike slip type earthquakes along the both flanks sinistral and dextral strike slip faults respectively. Earthquakes of epi continental arc type is characterised by segmentation in space and periodicity in time.
文摘The perioperative management of 81 cases with pheochromocytoma was reviewed including blood pressure and arrhythmia control, blood volume expansion, patient′s general condition improvement and vital signs monitoring. It was stressed that pre and intra operative management was of prime importance in the treatment of pheochromocytoma.
文摘<strong>Objective:</strong><span style="white-space:normal;font-size:10pt;font-family:;" "=""> This work aimed to evaluate the epidemiological clinical aspects and evolutionary aspects of peri partum cardiomyopathy (PPCM) in the cardiology department of the CHU Point G. <b>Materials and Methods:</b> This was a descriptive cross-sectional study from </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">0</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">1 January 2019 to 31 December 2019, including all patients admitted for heart failure during this period.<b> Results:</b> The study involved 40 patients out of 1187 admissions, a hospital prevalence of PPCM was 3.36%. The average age was 26 years plus or minus 7 years with extremes of 16 years and 38 years. The age group between 16 and 20 years was the most represented with 32.5% of cases. Housewives were in the majority with 87.6%;residing in rural areas 62.5%, with a low socio-economic standard of living 32.5% of cases. Multiparous in our context were dominant 42.5%, followed by pauci pares and primiparous with 32.5% and 25% frequency respectively. All our patients, 100% had their first symptom after childbirth, functional signs were dominated by dyspnea of effort present in 100% of patients, followed cough (40%) and chest pain (27.5%). On physical examination there was Tachycardia in 82.5%, Galop B3 (45%) and auscultatory arrhythmia in 5%. Signs of pulmonary condensation (82.5%) and pleural fluid effusion (25%). Hepatomegaly was present in 72.5% of patients. It was overall heart failure in 72.5% of cases. On the electrocardiogram there was sinus tachycardia (75%) and atrial fibrillation arrhythmia (5%). On cardiac Doppler ultrasound the left ventricle was dilated with a low systolic ejection fraction in 100% of patients, the four cavities were dilated in 32.5%, a left intraventricular thrombus in 7.5% of cases and a pericardial fluid effusion in 5% of cases. Biology noted anemia in 22.5% of patients. Treatment was classic for heart failure. The course was punctuated by complications in 42.5% of cases, such as thromboembolic disease (22.5%), ischemic stroke (12.5%), complete arrhythmia by atrial fibrillation (ACFA 5%) and cardiogenic shock (2.5%). Hospital mortality was 7.5% with 67% of deaths observed in the 16</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">-</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">22 age group. </span><span style="white-space:normal;font-size:10pt;font-family:;" "=""><b>Conclusion:</b> PPCM is a common sub-Saharan pathology, low socioeconomic status, young age and multiparity were factors dominant in our context.</span>
文摘Objective: to study the practical value of rapid rehabilitation nursing for patients undergoing radical prostatectomy. Methods: the control group received routine nursing. The rehabilitation group received rapid rehabilitation nursing. Results: all indexes of rehabilitation group were better than those of control group (P<0.05). Conclusion: rapid rehabilitation nursing has better nursing effect. It is suggested to use it for reference in nursing work.
