目的:为进一步开发与应用儿童生存质量测量量表(PedsQL)提供参考。方法:以“PedsQL”为检索词系统检索Medline、ScienceDirect、Cochrane图书馆、ISI Web of Science、SpringerLink、Embase、中国知网、万方数据、维普网、中国生物医学...目的:为进一步开发与应用儿童生存质量测量量表(PedsQL)提供参考。方法:以“PedsQL”为检索词系统检索Medline、ScienceDirect、Cochrane图书馆、ISI Web of Science、SpringerLink、Embase、中国知网、万方数据、维普网、中国生物医学文献服务系统等中英文数据库,对发表日期为1999年1月-2019年12月的有关PedsQL在国内外的应用研究文献进行检索。结果与结论:共纳入文献2117篇,其中国外文献1836篇、国内文献281篇(中文242篇、英文39篇);文献发表数量基本呈现逐年增长的趋势。PedsQL量表在国内外应用广泛,依据用途可划分为4个主要领域,分别为健康影响因素分析(63项研究)、疾病负担评估(1720项研究)、干预措施效果评价(285项研究)、其他量表的理论研究(49项研究)。PedsQL量表应用于临床研究进展迅速,但我国研究仍存在量表的选择与使用方法不当、在儿科临床实践领域应用偏少、对干预措施评价不够全面的问题。建议学者未来在选用工具时同时考虑普适性与疾病特异性、自填与家长代理版本PedsQL量表,应用PedsQL量表实施常规的临床健康相关生存质量筛查以优化儿科卫生资源使用效率,构建基于我国人群偏好的PedsQL量表映射函数以进行药物干预措施的经济学评价。展开更多
Although refugee adolescents and children are recognised as a health risk population, few studies have explored their Health-related Quality of Life (HRQOL). The present study investigated 1) the sociodemographic pred...Although refugee adolescents and children are recognised as a health risk population, few studies have explored their Health-related Quality of Life (HRQOL). The present study investigated 1) the sociodemographic predictors of HRQOL such as ethnicity, trauma exposure, and length of residency in Australia in a multiethnic paediatric population with refugee experiences and 2) the relationship between mental healthcare utilisation and HRQOL. Method: Participants were 458 adolescents and children, aged 4 - 17 years, living in South Australia. Parents provided data across the sample and adolescents also completed questionnaires. Overall HRQOL and its composite functional dimensions were assessed using the Paediatric Quality of Life (PedsQL) instrument. Questions from the Child and Adolescent Component of the Australian National Survey of Mental Health and Wellbeing were used to assess service utilisation. Results: Migration region/ethnicity predicted better HRQOL as well as physical, emotional and psychosocial functioning for both children and adolescents. African youths indicated higher HRQOL than those from the former Yugoslavia and the Middle East/South Asia respectively. Pre-migration trauma exposure was associated with lower HRQOL;and longer stay in Australia was related to lower emotional functioning in children. There was a negative association between healthcare service utilisation and PedsQL scores, with participants accessing services demonstrating lower HRQOL. Conclusion: Using more rigorous methods, future research is needed to investigate additional sociodemographic predictors of HRQOL, and protective/risk factors that impact on HRQOL of young refugees.展开更多
目的：探讨下肢A型肉毒毒素（botulinum toxin type A，BTX—A）注射治疗对痉挛型双瘫患儿躯体运动功能和健康相关生活质量的影响。方法：51例2岁1个月～9岁6个月痉挛型双瘫患儿随机分为BTX—A注射组26例和对照组25例。患儿均给予系统...目的：探讨下肢A型肉毒毒素（botulinum toxin type A，BTX—A）注射治疗对痉挛型双瘫患儿躯体运动功能和健康相关生活质量的影响。方法：51例2岁1个月～9岁6个月痉挛型双瘫患儿随机分为BTX—A注射组26例和对照组25例。患儿均给予系统性康复治疗6个月，注射组在人组第一天给予1次BTX—A注射治疗。在治疗前，治疗后1个月、3个月、6个月对患儿运动功能和生活质量进干亍评估。结果：注射组与对照组相比用改良Ashworth量表（Modified Ashworth Scale，MAS）量化评分组间差异有统计学意义（P〈0．05）；注射组与对照组相比粗大运动功能评分（Gross Motor Function Measure，GMFM）走跑跳功能评分组间差异有统计学意义（P〈0．05）；儿科生活质量调查表（The Pediatric Quality of Life Inventory Measurement Models, PedsQL）生理领域的时间因素以及时间凶素和分组的交互作用比较有统计学意义（P〈0．05），注射组提高趋势更明显。而心理领域差异无统计学意义（P〉0．05）。结论：A型肉毒毒素辅助治疗能更有效改善脑瘫患儿的肌肉痉挛和运动功能，但是短时间内对其社会、心理、情感等方面的功能无明显改善作用。展开更多
文摘目的:为进一步开发与应用儿童生存质量测量量表(PedsQL)提供参考。方法:以“PedsQL”为检索词系统检索Medline、ScienceDirect、Cochrane图书馆、ISI Web of Science、SpringerLink、Embase、中国知网、万方数据、维普网、中国生物医学文献服务系统等中英文数据库,对发表日期为1999年1月-2019年12月的有关PedsQL在国内外的应用研究文献进行检索。结果与结论:共纳入文献2117篇,其中国外文献1836篇、国内文献281篇(中文242篇、英文39篇);文献发表数量基本呈现逐年增长的趋势。PedsQL量表在国内外应用广泛,依据用途可划分为4个主要领域,分别为健康影响因素分析(63项研究)、疾病负担评估(1720项研究)、干预措施效果评价(285项研究)、其他量表的理论研究(49项研究)。PedsQL量表应用于临床研究进展迅速,但我国研究仍存在量表的选择与使用方法不当、在儿科临床实践领域应用偏少、对干预措施评价不够全面的问题。建议学者未来在选用工具时同时考虑普适性与疾病特异性、自填与家长代理版本PedsQL量表,应用PedsQL量表实施常规的临床健康相关生存质量筛查以优化儿科卫生资源使用效率,构建基于我国人群偏好的PedsQL量表映射函数以进行药物干预措施的经济学评价。
文摘Although refugee adolescents and children are recognised as a health risk population, few studies have explored their Health-related Quality of Life (HRQOL). The present study investigated 1) the sociodemographic predictors of HRQOL such as ethnicity, trauma exposure, and length of residency in Australia in a multiethnic paediatric population with refugee experiences and 2) the relationship between mental healthcare utilisation and HRQOL. Method: Participants were 458 adolescents and children, aged 4 - 17 years, living in South Australia. Parents provided data across the sample and adolescents also completed questionnaires. Overall HRQOL and its composite functional dimensions were assessed using the Paediatric Quality of Life (PedsQL) instrument. Questions from the Child and Adolescent Component of the Australian National Survey of Mental Health and Wellbeing were used to assess service utilisation. Results: Migration region/ethnicity predicted better HRQOL as well as physical, emotional and psychosocial functioning for both children and adolescents. African youths indicated higher HRQOL than those from the former Yugoslavia and the Middle East/South Asia respectively. Pre-migration trauma exposure was associated with lower HRQOL;and longer stay in Australia was related to lower emotional functioning in children. There was a negative association between healthcare service utilisation and PedsQL scores, with participants accessing services demonstrating lower HRQOL. Conclusion: Using more rigorous methods, future research is needed to investigate additional sociodemographic predictors of HRQOL, and protective/risk factors that impact on HRQOL of young refugees.
文摘目的：探讨下肢A型肉毒毒素（botulinum toxin type A，BTX—A）注射治疗对痉挛型双瘫患儿躯体运动功能和健康相关生活质量的影响。方法：51例2岁1个月～9岁6个月痉挛型双瘫患儿随机分为BTX—A注射组26例和对照组25例。患儿均给予系统性康复治疗6个月，注射组在人组第一天给予1次BTX—A注射治疗。在治疗前，治疗后1个月、3个月、6个月对患儿运动功能和生活质量进干亍评估。结果：注射组与对照组相比用改良Ashworth量表（Modified Ashworth Scale，MAS）量化评分组间差异有统计学意义（P〈0．05）；注射组与对照组相比粗大运动功能评分（Gross Motor Function Measure，GMFM）走跑跳功能评分组间差异有统计学意义（P〈0．05）；儿科生活质量调查表（The Pediatric Quality of Life Inventory Measurement Models, PedsQL）生理领域的时间因素以及时间凶素和分组的交互作用比较有统计学意义（P〈0．05），注射组提高趋势更明显。而心理领域差异无统计学意义（P〉0．05）。结论：A型肉毒毒素辅助治疗能更有效改善脑瘫患儿的肌肉痉挛和运动功能，但是短时间内对其社会、心理、情感等方面的功能无明显改善作用。
