2型糖尿病(T2DM)已经成为全球范围内一个日益严峻的健康问题,其发病机制的复杂性涉及众多生理和病理过程的相互作用。在近年来的研究中,越来越多的科学家和医学专家开始关注睡眠障碍,特别是失眠和阻塞性睡眠呼吸暂停(OSA)这两种普遍存...2型糖尿病(T2DM)已经成为全球范围内一个日益严峻的健康问题,其发病机制的复杂性涉及众多生理和病理过程的相互作用。在近年来的研究中,越来越多的科学家和医学专家开始关注睡眠障碍,特别是失眠和阻塞性睡眠呼吸暂停(OSA)这两种普遍存在的睡眠障碍类型。这些睡眠问题与2型糖尿病之间存在着紧密的关联。本文旨在综述该领域最新的机制研究以及治疗进展,深入探讨失眠和OSA在T2DM的发病机制,以及疾病进展对T2DM患者的影响,并对相关的治疗策略进行讨论。Type 2 diabetes mellitus (T2DM) has become a growing health problem worldwide, and the complexity of its pathogenesis involves the interaction of numerous physiologic and pathologic processes. In recent years, an increasing number of scientists and medical experts have begun to focus on sleep disorders, particularly insomnia and obstructive sleep apnea (OSA), two prevalent types of sleep disorders. There is a strong association between these sleep problems and type 2 diabetes. The aim of this paper is to review the latest mechanistic studies as well as therapeutic advances in this field, to provide insights into the pathogenesis of insomnia and OSA in T2DM, as well as the impact of disease progression on patients with T2DM, and to discuss related therapeutic strategies.展开更多
文摘2型糖尿病(T2DM)已经成为全球范围内一个日益严峻的健康问题,其发病机制的复杂性涉及众多生理和病理过程的相互作用。在近年来的研究中,越来越多的科学家和医学专家开始关注睡眠障碍,特别是失眠和阻塞性睡眠呼吸暂停(OSA)这两种普遍存在的睡眠障碍类型。这些睡眠问题与2型糖尿病之间存在着紧密的关联。本文旨在综述该领域最新的机制研究以及治疗进展,深入探讨失眠和OSA在T2DM的发病机制,以及疾病进展对T2DM患者的影响,并对相关的治疗策略进行讨论。Type 2 diabetes mellitus (T2DM) has become a growing health problem worldwide, and the complexity of its pathogenesis involves the interaction of numerous physiologic and pathologic processes. In recent years, an increasing number of scientists and medical experts have begun to focus on sleep disorders, particularly insomnia and obstructive sleep apnea (OSA), two prevalent types of sleep disorders. There is a strong association between these sleep problems and type 2 diabetes. The aim of this paper is to review the latest mechanistic studies as well as therapeutic advances in this field, to provide insights into the pathogenesis of insomnia and OSA in T2DM, as well as the impact of disease progression on patients with T2DM, and to discuss related therapeutic strategies.
