1文献来源FRENCH C A,KUTOK J L,FAQUIN W C,et al.Midline carcinoma of children and young adults with NUT rearrangement[J].J Clin Oncol,2004,22(20):4135-4139.doi:10.1200/JCO.2004.02.107.2研究背景既往病例报道描述了一种罕...1文献来源FRENCH C A,KUTOK J L,FAQUIN W C,et al.Midline carcinoma of children and young adults with NUT rearrangement[J].J Clin Oncol,2004,22(20):4135-4139.doi:10.1200/JCO.2004.02.107.2研究背景既往病例报道描述了一种罕见的癌症--NUT癌,它常发生在年轻人中并具有t(15;19)染色体易位的特征,该特征似乎与高致死性的临床进程相关。特殊的染色体易位是其独特标识,但大多数癌具有高度的同源性及多重核型,诊断性染色体平衡易位较缺乏。就细胞遗传学特征而言,NUT癌更类似于淋巴瘤及肉瘤。仅有的文献表明,该癌肿属于主要起源于胸腺或呼吸道上皮的实体瘤,对放化疗无明显效应,具有高度致命性,但这种疾病的临床病理特征仍不明确,需要进一步研究探索。展开更多
Purpose: The purpose of this study was to examine the association between almond consumption, the most widely consumed tree nut in the US, and nutrient intake, nutrient adequacy, diet quality, and weight/adiposity in ...Purpose: The purpose of this study was to examine the association between almond consumption, the most widely consumed tree nut in the US, and nutrient intake, nutrient adequacy, diet quality, and weight/adiposity in adults. Methods: Data from adults (N=24,808), 19+ years, participating in the NHANES 2001-2010 were used. The NCI method was used to estimate the usual intake of almonds and selected nutrients. Almond consumers were defined as those consuming any amount of almonds/almond butter. Percentages of the consumers/non-consumers below the Estimated Average Requirement (EAR) or above the Adequate Intake (AI) for select nutrients were determined. To assess significant differences for the percentage of almond consumers vs. non-consumers with intakes less than the EAR or above the AI, a Z-statistic for differences in population proportions was used. Covariate-controlled linear regression was used to determine differences in diet quality, measured by the Healthy Eating Index-2010 (HEI-2010), between the consumer groups. Body mass indices and waist circumference were assessed. P was set at p < 0.01. Results: Almond consumers were more likely to be non-Hispanic white, older, of higher income, more physically active, and were less likely to be a current smoker than non-consumers. Usual intake of almonds among consumers was 29.5 ± 1.5 g/day. Usual intake of protein;dietary fiber;vitamins A, D, E, and C;thiamin;niacin;riboflavin;folate, calcium, copper, magnesium, iron, phosphorus, selenium, zinc, and potassium was higher in almond consumers. Almond consumers were less likely to be below the EAR for protein, vitamins A, D, E, B12, and C;riboflavin;calcium;copper;magnesium;iron;phosphorus;and zinc. They were also more likely to be above the AI for dietary fiber and potassium. Total HEI-2010 scores were approximately 15 points higher in almond consumers. Body mass indices and waist circumference measures were lower in almond consumers. Conclusions: Moderate consumption of almonds should be encouraged as part of a healthy diet.展开更多
伴睾丸核蛋白(nuclear protein in testis,NUT)基因重排的中线癌又称NUT癌,是一种罕见的高度侵袭性肿瘤,根据NUT中线癌家族成员1(NUT midline carcinoma family member 1,NUTM1)基因发生重排或突变定义。常规治疗方法对NUT癌效果欠佳,...伴睾丸核蛋白(nuclear protein in testis,NUT)基因重排的中线癌又称NUT癌,是一种罕见的高度侵袭性肿瘤,根据NUT中线癌家族成员1(NUT midline carcinoma family member 1,NUTM1)基因发生重排或突变定义。常规治疗方法对NUT癌效果欠佳,绝大多数患者预后差。现阶段对该基因变异的认识不足是制约NUT癌诊治取得进展的主要障碍。目前在临床实践中缺乏针对NUT癌临床特征、诊断及治疗方法的标准化指南,限制了临床医师对该疾病的充分认识。为了给临床医师提供更加明确规范的诊断参考依据,中国抗癌协会肿瘤基因诊断专业委员会中线(NUT)癌基因诊断工作组及中国抗癌协会肿瘤标志专业委员会组织了临床、病理、分子检测和生物信息分析等领域专家,综合国内外NUT癌临床应用的共识指南、重要文献及临床实践经验,共同制定了本共识,对NUT癌临床诊疗给出专家组意见,期望为临床医师提供NUT癌诊疗指导意见,降低NUT癌误诊率,提高治疗效果和预后。展开更多
In order to improve the yield and quality of 5 new Castanea mollissima varieties “Zipo”, “Zunyu” and traditional Yan Mountain Castanea mollissima cultivars “Duanci”, “Yanhong” and “Donglingmingzhu”, we carri...In order to improve the yield and quality of 5 new Castanea mollissima varieties “Zipo”, “Zunyu” and traditional Yan Mountain Castanea mollissima cultivars “Duanci”, “Yanhong” and “Donglingmingzhu”, we carried out an experiment to study effect from different varieties configuration on yield of Yan Mountain chestnut. The result indicated that: cross-pollination had a significant impact on both fruiting rate and seed-setting rate;cross-pollination improved the nut number in each burr of each variety, in which “Duanci” was the biggest beneficiary, whose number of nut per burr increased from 1.08 to 2.77, 156% higher than that of the self-pollination combination;nut weight showed no significant difference in Xenia Effection;“Zunyu” improved the yield of “Yanhong” most;“Donglingmingzhu” was regarded as the best tree to improve “Zunyu”’s yield;the best variety to improve yield of “Zipo” was “Zunyu”;“Donglingmingzhu” and “Duanci” improved yield of each other most.展开更多
In order to screen herbicides with ideal safety characteristics to control malignant weed nut grass in sugarcane field, 20% thifensulfuron methyl WP and 65% MCPA·ametryne·diuron WP were selected for the fiel...In order to screen herbicides with ideal safety characteristics to control malignant weed nut grass in sugarcane field, 20% thifensulfuron methyl WP and 65% MCPA·ametryne·diuron WP were selected for the field efficacy trial. The results showed that 20% thifensulfuron methyl WP and 65% MCPA·ametryne·diuron WP had good control effect on nut grass. The optimum dosage of 20% thifensulfuron methyl WP and 65% MCPA.ametryne-diuron WP was 1 125 g/hm^2 （effective ingredients 225 g） and 3 150 g/hm^2 （effective ingredients 2 047.5 g）, respectively. These two herbicides should be dissolved in 675 kg water per hectare and applied in the vigorous growth period of nut grass （height 10-15 cm） with oriented stem leaf spraying. The control effect after 15 days could be above 87.9%.展开更多
While some reports show that physical characteristics of the baru fruits (Dipteryx alata Vog.) differ within and among the Brazilian Savanna regions, a study shows that there are differences in the nutritional composi...While some reports show that physical characteristics of the baru fruits (Dipteryx alata Vog.) differ within and among the Brazilian Savanna regions, a study shows that there are differences in the nutritional composition of baru almonds from different trees from the same Savanna area. It is unknown, however, whether the Savanna’s region influences the nutritional quality of this native almond. Thus, we evaluated the influence of East, Southeast and West regions of the Brazilian Savanna on physical characteristics, nutrient composition and protein quality of the baru almond. Chemical composition and amino acid profile were analyzed, and Amino Acid Score (AAS), Net Protein Ratio (NPR), and Protein Digestibility–Corrected Amino Acid Score (PDCAAS) were estimated. The physical characteristics significantly differed within but not among regions. The protein (310 g kg-1), lipid (410 g·kg-1), fiber (120 g·kg-1) and calcium (1,300 mg·kg-1) contents of baru almonds were high, with significant differences among regions for insoluble fiber content (94.3 - 128.3 g·kg-1) and amino acid profile (AAS = 77% - 89%). The relative NPR (RNPR) values were similar among regions (mean value of RNPR = 71%), and the PDCAAS values ranged from 65 to 73%. The region of the Brazilian Savanna influences the fiber and amino acid profiles, but not the total content of nutrients, the protein quality and the physical characteristics of the native baru almonds. The baru almond is a potential food as source of complementary protein for healthy diets and as a nutritious raw material for various food systems.展开更多
NUT癌(NUT carcinoma)又称为伴睾丸核蛋白(the nuclear protein of the testis,NUT)基因重排的中线癌,它是一种组织起源不明的高度侵袭性的恶性肿瘤,非常罕见。以前人们认为该病仅发生于中线器官,但随着病例的积累,现在认为它不仅发生...NUT癌(NUT carcinoma)又称为伴睾丸核蛋白(the nuclear protein of the testis,NUT)基因重排的中线癌,它是一种组织起源不明的高度侵袭性的恶性肿瘤,非常罕见。以前人们认为该病仅发生于中线器官,但随着病例的积累,现在认为它不仅发生于中线器官,还可以发生于非中线器官,如腮腺、颌下腺等。展开更多
文摘1文献来源FRENCH C A,KUTOK J L,FAQUIN W C,et al.Midline carcinoma of children and young adults with NUT rearrangement[J].J Clin Oncol,2004,22(20):4135-4139.doi:10.1200/JCO.2004.02.107.2研究背景既往病例报道描述了一种罕见的癌症--NUT癌,它常发生在年轻人中并具有t(15;19)染色体易位的特征,该特征似乎与高致死性的临床进程相关。特殊的染色体易位是其独特标识,但大多数癌具有高度的同源性及多重核型,诊断性染色体平衡易位较缺乏。就细胞遗传学特征而言,NUT癌更类似于淋巴瘤及肉瘤。仅有的文献表明,该癌肿属于主要起源于胸腺或呼吸道上皮的实体瘤,对放化疗无明显效应,具有高度致命性,但这种疾病的临床病理特征仍不明确,需要进一步研究探索。
文摘Purpose: The purpose of this study was to examine the association between almond consumption, the most widely consumed tree nut in the US, and nutrient intake, nutrient adequacy, diet quality, and weight/adiposity in adults. Methods: Data from adults (N=24,808), 19+ years, participating in the NHANES 2001-2010 were used. The NCI method was used to estimate the usual intake of almonds and selected nutrients. Almond consumers were defined as those consuming any amount of almonds/almond butter. Percentages of the consumers/non-consumers below the Estimated Average Requirement (EAR) or above the Adequate Intake (AI) for select nutrients were determined. To assess significant differences for the percentage of almond consumers vs. non-consumers with intakes less than the EAR or above the AI, a Z-statistic for differences in population proportions was used. Covariate-controlled linear regression was used to determine differences in diet quality, measured by the Healthy Eating Index-2010 (HEI-2010), between the consumer groups. Body mass indices and waist circumference were assessed. P was set at p < 0.01. Results: Almond consumers were more likely to be non-Hispanic white, older, of higher income, more physically active, and were less likely to be a current smoker than non-consumers. Usual intake of almonds among consumers was 29.5 ± 1.5 g/day. Usual intake of protein;dietary fiber;vitamins A, D, E, and C;thiamin;niacin;riboflavin;folate, calcium, copper, magnesium, iron, phosphorus, selenium, zinc, and potassium was higher in almond consumers. Almond consumers were less likely to be below the EAR for protein, vitamins A, D, E, B12, and C;riboflavin;calcium;copper;magnesium;iron;phosphorus;and zinc. They were also more likely to be above the AI for dietary fiber and potassium. Total HEI-2010 scores were approximately 15 points higher in almond consumers. Body mass indices and waist circumference measures were lower in almond consumers. Conclusions: Moderate consumption of almonds should be encouraged as part of a healthy diet.
文摘伴睾丸核蛋白(nuclear protein in testis,NUT)基因重排的中线癌又称NUT癌,是一种罕见的高度侵袭性肿瘤,根据NUT中线癌家族成员1(NUT midline carcinoma family member 1,NUTM1)基因发生重排或突变定义。常规治疗方法对NUT癌效果欠佳,绝大多数患者预后差。现阶段对该基因变异的认识不足是制约NUT癌诊治取得进展的主要障碍。目前在临床实践中缺乏针对NUT癌临床特征、诊断及治疗方法的标准化指南,限制了临床医师对该疾病的充分认识。为了给临床医师提供更加明确规范的诊断参考依据,中国抗癌协会肿瘤基因诊断专业委员会中线(NUT)癌基因诊断工作组及中国抗癌协会肿瘤标志专业委员会组织了临床、病理、分子检测和生物信息分析等领域专家,综合国内外NUT癌临床应用的共识指南、重要文献及临床实践经验,共同制定了本共识,对NUT癌临床诊疗给出专家组意见,期望为临床医师提供NUT癌诊疗指导意见,降低NUT癌误诊率,提高治疗效果和预后。
文摘In order to improve the yield and quality of 5 new Castanea mollissima varieties “Zipo”, “Zunyu” and traditional Yan Mountain Castanea mollissima cultivars “Duanci”, “Yanhong” and “Donglingmingzhu”, we carried out an experiment to study effect from different varieties configuration on yield of Yan Mountain chestnut. The result indicated that: cross-pollination had a significant impact on both fruiting rate and seed-setting rate;cross-pollination improved the nut number in each burr of each variety, in which “Duanci” was the biggest beneficiary, whose number of nut per burr increased from 1.08 to 2.77, 156% higher than that of the self-pollination combination;nut weight showed no significant difference in Xenia Effection;“Zunyu” improved the yield of “Yanhong” most;“Donglingmingzhu” was regarded as the best tree to improve “Zunyu”’s yield;the best variety to improve yield of “Zipo” was “Zunyu”;“Donglingmingzhu” and “Duanci” improved yield of each other most.
基金Supported by Earmarked Fund for China Agriculture Research System(CARS-20-2-2)Project for Yunnan Provincial Modern Agricultural Industry Technology System(YNGZTX-4-92)~~
文摘In order to screen herbicides with ideal safety characteristics to control malignant weed nut grass in sugarcane field, 20% thifensulfuron methyl WP and 65% MCPA·ametryne·diuron WP were selected for the field efficacy trial. The results showed that 20% thifensulfuron methyl WP and 65% MCPA·ametryne·diuron WP had good control effect on nut grass. The optimum dosage of 20% thifensulfuron methyl WP and 65% MCPA.ametryne-diuron WP was 1 125 g/hm^2 （effective ingredients 225 g） and 3 150 g/hm^2 （effective ingredients 2 047.5 g）, respectively. These two herbicides should be dissolved in 675 kg water per hectare and applied in the vigorous growth period of nut grass （height 10-15 cm） with oriented stem leaf spraying. The control effect after 15 days could be above 87.9%.
文摘While some reports show that physical characteristics of the baru fruits (Dipteryx alata Vog.) differ within and among the Brazilian Savanna regions, a study shows that there are differences in the nutritional composition of baru almonds from different trees from the same Savanna area. It is unknown, however, whether the Savanna’s region influences the nutritional quality of this native almond. Thus, we evaluated the influence of East, Southeast and West regions of the Brazilian Savanna on physical characteristics, nutrient composition and protein quality of the baru almond. Chemical composition and amino acid profile were analyzed, and Amino Acid Score (AAS), Net Protein Ratio (NPR), and Protein Digestibility–Corrected Amino Acid Score (PDCAAS) were estimated. The physical characteristics significantly differed within but not among regions. The protein (310 g kg-1), lipid (410 g·kg-1), fiber (120 g·kg-1) and calcium (1,300 mg·kg-1) contents of baru almonds were high, with significant differences among regions for insoluble fiber content (94.3 - 128.3 g·kg-1) and amino acid profile (AAS = 77% - 89%). The relative NPR (RNPR) values were similar among regions (mean value of RNPR = 71%), and the PDCAAS values ranged from 65 to 73%. The region of the Brazilian Savanna influences the fiber and amino acid profiles, but not the total content of nutrients, the protein quality and the physical characteristics of the native baru almonds. The baru almond is a potential food as source of complementary protein for healthy diets and as a nutritious raw material for various food systems.
文摘NUT癌(NUT carcinoma)又称为伴睾丸核蛋白(the nuclear protein of the testis,NUT)基因重排的中线癌,它是一种组织起源不明的高度侵袭性的恶性肿瘤,非常罕见。以前人们认为该病仅发生于中线器官,但随着病例的积累,现在认为它不仅发生于中线器官,还可以发生于非中线器官,如腮腺、颌下腺等。
