Need等[1]于2012年发现,由NGLY1基因突变导致的N-糖苷酶缺陷,会引起一种新的糖基化障碍(congenital disorder of glycosylation,CDG)。后续的研究发现,该病为常染色体隐性遗传性疾病[1-4],又命名为NGLY1型先天性去糖基化障碍(NGLY1-rela...Need等[1]于2012年发现,由NGLY1基因突变导致的N-糖苷酶缺陷,会引起一种新的糖基化障碍(congenital disorder of glycosylation,CDG)。后续的研究发现,该病为常染色体隐性遗传性疾病[1-4],又命名为NGLY1型先天性去糖基化障碍(NGLY1-related congenital disorder of deglycosylation,简写为NGLY1-CDDG)[4]。展开更多
In the present study, a great effort was made to improve the performance of an industrial liquefied petroleum gas(LPG) and natural gas liquid(NGL) production unit in one of the major gas refinery located at Pars speci...In the present study, a great effort was made to improve the performance of an industrial liquefied petroleum gas(LPG) and natural gas liquid(NGL) production unit in one of the major gas refinery located at Pars special economic zone in Iran. To demonstrate and obtain the optimal condition, the unit was simulated by using a steady-state flowsheet simulator, i.e. Aspen Plus, under different operational conditions. According to the simulation results,the unit was not operational under its optimal conditions due to some defects in the cooling system at top stage of the debutanizer tower(DBT) during hot and humid seasons. Additionally, the vapor pressure of produced LPG and accordingly the amount of its flaring were decreased by reducing the temperature of debutanizer tower at top stages. In the optimization section, the DBT condenser and reboiler heat duty, temperature, and pressure were regulated as adjustable parameters. The simulation results demonstrated that by applying the optimum suggestion in the hot months, the reflux stream temperature was reached about 55 ℃ which caused an efficient increment in LPG production(about 4%) with adjusting the propane component in LPG, based on the standard range as the plant criteria. Moreover, after applying modifications, about 750 t of LPG product was saved from flaring during five hot months of the year, which resulted in 360000 USD extra annual income for the company.Finally, from environmental point of view, this optimization caused to reduce 81 t of CO_2 emission to the environment. Therefore, the current investigation must be introduced as a friendly environmentally process.展开更多
文摘Need等[1]于2012年发现,由NGLY1基因突变导致的N-糖苷酶缺陷,会引起一种新的糖基化障碍(congenital disorder of glycosylation,CDG)。后续的研究发现,该病为常染色体隐性遗传性疾病[1-4],又命名为NGLY1型先天性去糖基化障碍(NGLY1-related congenital disorder of deglycosylation,简写为NGLY1-CDDG)[4]。
文摘In the present study, a great effort was made to improve the performance of an industrial liquefied petroleum gas(LPG) and natural gas liquid(NGL) production unit in one of the major gas refinery located at Pars special economic zone in Iran. To demonstrate and obtain the optimal condition, the unit was simulated by using a steady-state flowsheet simulator, i.e. Aspen Plus, under different operational conditions. According to the simulation results,the unit was not operational under its optimal conditions due to some defects in the cooling system at top stage of the debutanizer tower(DBT) during hot and humid seasons. Additionally, the vapor pressure of produced LPG and accordingly the amount of its flaring were decreased by reducing the temperature of debutanizer tower at top stages. In the optimization section, the DBT condenser and reboiler heat duty, temperature, and pressure were regulated as adjustable parameters. The simulation results demonstrated that by applying the optimum suggestion in the hot months, the reflux stream temperature was reached about 55 ℃ which caused an efficient increment in LPG production(about 4%) with adjusting the propane component in LPG, based on the standard range as the plant criteria. Moreover, after applying modifications, about 750 t of LPG product was saved from flaring during five hot months of the year, which resulted in 360000 USD extra annual income for the company.Finally, from environmental point of view, this optimization caused to reduce 81 t of CO_2 emission to the environment. Therefore, the current investigation must be introduced as a friendly environmentally process.
