Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.展开更多
如果你是一位从DOS时代走过来的DIYer，那么一定听说过NDD(Norton Disk Doctor)的大名，它除了有与Windows自带的磁盘扫描相似的功能外，还可用于检测和修复磁盘经常出现的文件碎片丢失、交叉链接文件、文件分配表损坏等。可以说是诺顿...如果你是一位从DOS时代走过来的DIYer，那么一定听说过NDD(Norton Disk Doctor)的大名，它除了有与Windows自带的磁盘扫描相似的功能外，还可用于检测和修复磁盘经常出现的文件碎片丢失、交叉链接文件、文件分配表损坏等。可以说是诺顿工具包中一位非常专业的磁盘医生。正因为这个原因，虽然操作系统早已由DOS进入Windows时代，但NDD一直被收入Norton Utillities工具包，在Norton System Works 2004中也可以找到它的踪影，因此我们现在也可以在Windows界面下轻松使用上它。展开更多
OMG的数据发布服务(Data Delivery Service)-实时发布-订阅已经成为一个标准,它提供了一个以数据为中心的网络中间件,使得实时环境下以数据为中心的分布式应用更加高效、易于编程。作为一个比较成熟的产品,RTI的NDDS(Network Data Deliv...OMG的数据发布服务(Data Delivery Service)-实时发布-订阅已经成为一个标准,它提供了一个以数据为中心的网络中间件,使得实时环境下以数据为中心的分布式应用更加高效、易于编程。作为一个比较成熟的产品,RTI的NDDS(Network Data Delivery Service)目前已经广泛应用到了美国海、陆、空、天各个领域,并发挥了作用,证明了DDS的可靠性和稳定性。结合NDDS,研究阐述了DDS的通信机制,提出了DDS中间件的设计构想。展开更多
文摘Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables this dynamic is the white matter(WM),known to be affected in neurodevelopmental disorders(NDDs)(Rokach et al.,2024).WM formation is mediated by myelination,a multifactorial process driven by neuro-glia interactions dependent on proper neuronal functionality(Simons and Trajkovic,2006).Another key aspect of neurodevelopmental abnormalities involves neuronal dynamics and function,with recent advances significantly enhancing our understanding of both neuronal and glial mitochondrial function(Devine and Kittler,2018;Rojas-Charry et al.,2021).Energy homeostasis in neurons,attributed largely to mitochondrial function,is critical for proper functionality and interactions with oligodendrocytes(OLs),the cells forming myelin in the brain’s WM.We herein discuss the interplay between these processes and speculate on potential dysfunction in NDDs.
文摘如果你是一位从DOS时代走过来的DIYer，那么一定听说过NDD(Norton Disk Doctor)的大名，它除了有与Windows自带的磁盘扫描相似的功能外，还可用于检测和修复磁盘经常出现的文件碎片丢失、交叉链接文件、文件分配表损坏等。可以说是诺顿工具包中一位非常专业的磁盘医生。正因为这个原因，虽然操作系统早已由DOS进入Windows时代，但NDD一直被收入Norton Utillities工具包，在Norton System Works 2004中也可以找到它的踪影，因此我们现在也可以在Windows界面下轻松使用上它。
