Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cycl...Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cyclization of intramolecule at room temperature in aqueous solution. The advantages of the novel protocol are the mild reaction condition, free organic solvent, simple final treatment, easy isolation of products and excellent yields.展开更多
As one of the countries that use the most concrete in the world, the development of concrete industry plays an important role in promoting the economic development of our country. Therefore, the actual operation of ea...As one of the countries that use the most concrete in the world, the development of concrete industry plays an important role in promoting the economic development of our country. Therefore, the actual operation of each concrete enterprise should be paid sufficient attention to. If the actual effect of concrete enterprises can be truly brought into full play, it will have an important impact on promoting the promotion of China's comprehensive national strength. But in the development process of concrete enterprises, they often have a great impact on the natural environment. Because the concrete enterprise is a very consumption of water resources industry. In the concrete pump pipe cleaning process, it will produce a large number of waste water waste residue, these waste water and waste residue will not only produce huge pollution to the surrounding residents of water resources, but also cause a great waste of water resources. At the same time, the production of a large number of industrial waste water will also have a bad effect on the development of concrete enterprises.展开更多
目的总结外固定支架针位护理最佳证据,为临床护理实践提供参考。方法基于“6S”证据资源金字塔模型,系统检索JBI循证卫生保健中心数据库、BMJ Best Practice、PubMed、Cochrane Library、UpToDate、NICE、医脉通、中国知网、万方知识数...目的总结外固定支架针位护理最佳证据,为临床护理实践提供参考。方法基于“6S”证据资源金字塔模型,系统检索JBI循证卫生保健中心数据库、BMJ Best Practice、PubMed、Cochrane Library、UpToDate、NICE、医脉通、中国知网、万方知识数据服务平台等数据库中与外固定支架针位护理相关的所有文献,文献类型包括指南、系统评价、专家共识、证据总结、随机对照试验等。检索时限为建库至2022年12月31日。由课题组成员根据相关文献质量评价标准独立进行质量评价,并结合专业判断对最终纳入文献进行提取整合、证据级别评定及汇总。结果共纳入文献13篇,并汇总13条证据,包括6个方面:外固定支架针位清洗液的选择、护理频次、敷料的选择、针道结痂的管理、是否按摩/按压针道位置及洗浴。结论该研究总结了外固定支架针位护理的最佳证据,建议临床医务人员结合临床实际选择性应用最佳证据,减少并发症的发生,改善患者结局。展开更多
基金Financial support from the National Natural Science Foundation of China(No.20802049) and Program for New Century Excellent Talents in University of Tianjin City
文摘Calix[4]-crown-5-sulfonyl cyclothiourea derivatives 6 and 7 were synthesized from calix[4]-crown-5-monosulfonylethylenediamine derivatives 4 and 5 and carbon disulfide through nucleophilic addition and subsequent cyclization of intramolecule at room temperature in aqueous solution. The advantages of the novel protocol are the mild reaction condition, free organic solvent, simple final treatment, easy isolation of products and excellent yields.
文摘As one of the countries that use the most concrete in the world, the development of concrete industry plays an important role in promoting the economic development of our country. Therefore, the actual operation of each concrete enterprise should be paid sufficient attention to. If the actual effect of concrete enterprises can be truly brought into full play, it will have an important impact on promoting the promotion of China's comprehensive national strength. But in the development process of concrete enterprises, they often have a great impact on the natural environment. Because the concrete enterprise is a very consumption of water resources industry. In the concrete pump pipe cleaning process, it will produce a large number of waste water waste residue, these waste water and waste residue will not only produce huge pollution to the surrounding residents of water resources, but also cause a great waste of water resources. At the same time, the production of a large number of industrial waste water will also have a bad effect on the development of concrete enterprises.
文摘目的总结外固定支架针位护理最佳证据,为临床护理实践提供参考。方法基于“6S”证据资源金字塔模型,系统检索JBI循证卫生保健中心数据库、BMJ Best Practice、PubMed、Cochrane Library、UpToDate、NICE、医脉通、中国知网、万方知识数据服务平台等数据库中与外固定支架针位护理相关的所有文献,文献类型包括指南、系统评价、专家共识、证据总结、随机对照试验等。检索时限为建库至2022年12月31日。由课题组成员根据相关文献质量评价标准独立进行质量评价,并结合专业判断对最终纳入文献进行提取整合、证据级别评定及汇总。结果共纳入文献13篇,并汇总13条证据,包括6个方面:外固定支架针位清洗液的选择、护理频次、敷料的选择、针道结痂的管理、是否按摩/按压针道位置及洗浴。结论该研究总结了外固定支架针位护理的最佳证据,建议临床医务人员结合临床实际选择性应用最佳证据,减少并发症的发生,改善患者结局。
